California Gold Nutrition Lutein with Zeaxanthin from Marigold Extract Review

California Gold Nutrition presents its Lutein with Zeaxanthin supplement, specifically formulated with 20 mg of these vital carotenoids, available in a convenient bottle of 60 veggie softgels. This product is designed to support overall macular health and aid in recovery from exposure to blue light, a common concern in today's digital world. Lutein and Zeaxanthin are powerful antioxidant carotenoids, naturally derived from Marigold flowers (M Gold Extract), which are crucial for protecting the body's cells from the damaging effects of free radicals. Their role extends significantly to the health and wellness of our eyes, making this supplement a key addition to an adult's daily regimen for maintaining optimal vision. The formulation of California Gold Nutrition Lutein with Zeaxanthin prioritizes purity and dietary inclusivity. These softgels are non-bovine, making them suitable for both vegetarians and vegans. Furthermore, the product adheres to strict quality standards, being formulated without gluten, GMOs, or soy, catering to individuals with specific dietary sensitivities or preferences. The manufacturing process takes place in a 3rd Party Audited cGMP Registered (Certified) Facility, underscoring the brand's commitment to quality and safety. This dedication is part of what California Gold Nutrition refers to as "The Gold Standard in Dietary Supplements" and "The Gold Difference," emphasizing a focused approach to wellness and rigorous CGN Testing. Each bottle contains 60 softgels, providing 60 total servings, assuming a serving size of one softgel. The item comes in a compact bottle, with product dimensions of 3.25 x 1.75 x 1.75 inches and a weight of 1.6 ounces. First made available on September 16, 2019, this supplement from California Gold Nutrition is positioned as an antioxidant and brightening agent for adult users. It's important to note the legal disclaimer that statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Consumers are advised to read labels and directions before use, and consult with a healthcare professional for medical advice. This product aims to offer a reliable and high-quality option for those seeking to support their eye health with essential carotenoids.

Product Focus: Eye Health
Tier ⓘ
Tier 2 · Rank 4
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 4 within Tier 2 for Eye Health; 4 of 39 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
80 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
100% of 48,098
Biohacker Mentions
5 of 10
Cost per month
$10

Study, Trial or Testing Result Summary

Members Only81 human studies · 52 improved
81 human studies52 improved16 no effect125,451 people studied

This product gives 20 mg of lutein and 1 mg of zeaxanthin a day, both from marigold flowers, and both at doses that have worked in studies. A pooled analysis of 20 randomized trials with 1,764 people found these pigments raised the protective pigment in the back of the eye more than placebo [1]. A pooled analysis of 9 trials found 10 or 20 mg of lutein a day improved sharpness of vision and contrast sensitivity, with bigger effects at higher doses and longer use [2]. In 120 healthy drivers, 20 mg of lutein daily for a year improved contrast and glare sensitivity, especially at night [3]. Zeaxanthin doses as low as 1 mg taken with lutein raised eye pigment over 12 months. A review of 13 trials with 85,321 people ranked lutein and zeaxanthin second, after zinc, for improving sharpness of vision in age related macular degeneration [4]. In a large 5 year trial of 4,203 older adults, 10 mg lutein plus 2 mg zeaxanthin did not significantly slow progression to advanced macular degeneration in the main analysis [5], though later analyses suggested about 9 to 10 percent lower risk [6][7]. Lutein did not prevent eye disease in premature babies. Animal and cell studies are never counted.

See all 81 studies →Hide the studies

Review Totals and Summary

Members Only48,098 reviews · 100% positive
48,098 reviews · IHerb 48,083 · Amazon 15
100% positive0% neutral0% negative

This California Gold Nutrition Lutein with Zeaxanthin from Marigold Extract has received overwhelmingly positive feedback, with approximately 48098 ratings across various stores, all of which are 4 or 5 stars. This indicates a very high level of customer satisfaction. **What buyers say it did for them** Many users report positive impacts on their eye health and vision. Some experienced an "indirectly boosting night vision" and found it easier for their eyes to adapt to twilight and darkness. Others noted that their "eyes feel less tired when working on the computer" and that their "vision seems clearer, especially in the evening." The supplement is also valued for its antioxidant properties, with some taking it as a "key defenses against Age Related Macular Degeneration." It is also mentioned to help support eye muscles. **Complaints** While overall satisfaction is high, a few users expressed uncertainty about the product's immediate or significant effects. Some were "not sure - that this did much of anything for my eyes," while others stated, "I am still waiting out in the benefits." These comments often came from users who experienced no negative side effects but also hadn't perceived dramatic positive changes yet, sometimes attributing this to a need for more consistent use. **Taste, smell, pill size or form** The physical attributes of the supplement are generally well-received. Customers frequently describe the pills or softgels as "small and easy to swallow, with no unpleasant taste." Many appreciate that they are "very easy to swallow even without water." The product is made from marigold extract, and the formula is noted to be natural and free from unnecessary additives. The packaging is also described as good and strong. **Value for money** Customers consistently view this product as offering good value. Reviews frequently highlight it as "Very good value for the buck" and praise its "Excellent quality for the price." The brand's association with iHerb is also seen as a guarantee of quality, reinforcing the perception of good value. The dosage of 20mg Lutein and 1mg Zeaxanthin is considered sufficient for a day. **Who it seems to suit and who it did not** This supplement appears to be particularly beneficial for individuals experiencing specific vision challenges, such as "night blindness" or difficulty adapting to low light conditions. It also appeals to those seeking support for general eye health, including after procedures like LASIK surgery, or as a preventative measure against age-related eye conditions. Users who are consistent with their daily intake seem to report more benefits. It did not seem to suit those looking for very rapid or dramatic changes, or those who struggled with consistent daily use.

Biohacker Summary

Members Only5 of 10 recommend it
5 of 10 biohackers on our panel recommend it

Lutein and zeaxanthin, the main ingredients, drew a mostly positive but mixed response from the panel, with about half recommending them and several staying neutral. Most of those who spoke focused on eye health, describing them as pigments that gather in the retina, filter blue light and may help protect against macular degeneration, and a few also pointed to brain and cognition benefits, and one to sleep. Doses mentioned were 4 to 5 milligrams of zeaxanthin and 5 to 20 milligrams a day of lutein, with one panelist noting that studies used 10 to 20 milligrams and that the data are still emerging. Several preferred getting them from foods such as eggs, kale and green leafy vegetables, with avocado noted as helping absorption, while others take them as supplements, one as part of a combined eye formula. One panelist stopped taking 20 milligrams of lutein a day after about a year because his skin turned slightly yellow, and another described the evidence for cataract protection as mixed and weak.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Zeaxanthin · neutral
    • 14 Oct 2026 · neutral · YouTube ↗
      Notes that eggs contain zeaxanthin, which can help the retina and improve night vision.
    • 14 Oct 2026 · Lutein · neutral · YouTube ↗
      Notes that eggs contain lutein, which can help the retina and improve night vision.
    • 10 Sep 2026 · neutral · Facebook ↗
      Mentions that egg yolks provide zeaxanthin, a carotenoid that accumulates in the retina and helps support eye health.
    • 10 Sep 2026 · Lutein · neutral · Facebook ↗
      Mentions that egg yolks provide lutein, a carotenoid that accumulates in the retina and helps support eye health.
    • 9 Sep 2026 · recommends · YouTube ↗
      Mentions that eggs contain zeaxanthin, an antioxidant that blocks blue radiation from the eyes, protecting against macular degeneration.
    • 9 Sep 2026 · recommends · YouTube ↗
      Highly recommends consuming zeaxanthin from egg yolks to protect the eye.
    • 9 Sep 2026 · Lutein · recommends · YouTube ↗
      Mentions that eggs contain lutein, an antioxidant that blocks blue radiation from the eyes, protecting against macular degeneration.
    • 9 Sep 2026 · Lutein · recommends · YouTube ↗
      Highly recommends consuming lutein from egg yolks to protect the eye.
    • 14 Aug 2026 · neutral · Facebook ↗
      Dr. Berg mentions that eggs contain Zeaxanthin, which supports the eyes.
    • 14 Aug 2026 · Lutein · neutral · Facebook ↗
      Dr. Berg mentions that eggs contain Lutein, which supports the eyes.
    • 13 Jul 2026 · Lutein · recommends · Podcast ↗
      Mentions that eggs also contain lutein, which is another important nutrient that supports brain health and cognitive health.
    • 11 Jul 2026 · Lutein · recommends · YouTube ↗
      States that lutein is very important for the brain, as the brain preferentially accumulates it to protect against damage to the myelin sheath.
    • 28 Nov 2025 · neutral · YouTube ↗
      Dr. Berg notes that egg yolks have carotenoids like zeaxanthin, which are good for the internal part of the arteries.
    • 28 Nov 2025 · Lutein · neutral · YouTube ↗
      Dr. Berg notes that egg yolks have carotenoids like lutein, which are good for the internal part of the arteries.
  • Siim Land · Lutein · neutral
    • 6 Sep 2026 · neutral · X ↗
      Notes that Lutein is one of several supplements with human evidence.
    • 5 Sep 2026 · neutral · X ↗
      Supplementing lutein and zeaxanthin 5-20 mg/day improves macular pigment optical density (MPOD), a marker of eye health, in people with healthy eyes.
    • 5 Sep 2026 · Zeaxanthin · neutral · X ↗
      Supplementing lutein and zeaxanthin 5-20 mg/day improves macular pigment optical density (MPOD), a marker of eye health, in people with healthy eyes.
    • 1 Jul 2026 · uses · YouTube ↗
      Tried 20 milligrams of lutein during this period to see if it affects eye strain.
    • 1 Jul 2026 · Zeaxanthin · uses · YouTube ↗
      Tried 5 milligrams of zeaxanthin during this period to see if it affects eye strain.
    • 12 Jun 2026 · recommends · YouTube ↗
      States that the main reason people take lutein and zeaxanthin is for eye health, and there is human clinical evidence that they improve eye health, reduce eye fatigue, and digital eye strain.
    • 1 Jun 2026 · uses · YouTube ↗
      Decided to try out lutein and zeaxanthin for 30 days to see if he noticed any changes on his eyesight, and he noticed less digital eye strain, slightly less blurry vision, and less dry eyes.
    • 1 Jun 2026 · Zeaxanthin · uses · YouTube ↗
      Decided to try out lutein and zeaxanthin for 30 days to see if he noticed any changes on his eyesight, and he noticed less digital eye strain, slightly less blurry vision, and less dry eyes.
    • 5 Jan 2026 · uses · YouTube ↗
      Will be trying lutein and zeaxanthin at 20mg and 5mg a day, respectively, for eye health, reducing digital eye strain, and protecting his eyes from excessive blue artificial light.
    • 28 Dec 2025 · recommends · YouTube ↗
      Places Lutein and Zeaxanthin in the 'god tier' because several clinical trials demonstrate their effectiveness in improving eyesight.
    • 28 Dec 2025 · Zeaxanthin · neutral · YouTube ↗
      Lists Zeaxanthin as one of his favorite 'god tier' supplements, based on research.
    • 13 Dec 2025 · uses · YouTube ↗
      Includes lutein in his 'all out' supplement stack and confirms he is currently taking it.
    • 13 Dec 2025 · Zeaxanthin · uses · YouTube ↗
      Includes zeaxanthin in his 'all out' supplement stack and confirms he is currently taking it.
    • 11 Dec 2025 · recommends · YouTube ↗
      Notes that lutein and zeaxanthin also have slight skin anti-aging benefits due to being powerful antioxidants, and improve inflammation, oxidized LDL, and blood sugar.
  • Dr. Rhonda Patrick · Zeaxanthin · neutral
    • 25 Aug 2026 · neutral · Facebook ↗
      Zeaxanthin may be among the most evidence-backed carotenoids for longevity. It accumulates in the brain, where higher levels are associated with greater crystallized intelligence, and supplementation can improve some measures of cognitive function. Evidence also suggests it may slow progression to advanced macular degeneration in high-risk individuals.
    • 25 Aug 2026 · Lutein · neutral · Facebook ↗
      Lutein may be among the most evidence-backed carotenoids for longevity. It accumulates in the brain, where higher levels are associated with greater crystallized intelligence, and supplementation can improve some measures of cognitive function. Evidence also suggests it may slow progression to advanced macular degeneration in high-risk individuals.
    • 24 Jul 2026 · Lutein · uses · Facebook ↗
      Consumes lutein through kale, noting its accumulation in the retina and brain for visual and cognitive function, and that avocado increases its absorption.
    • 29 Jun 2026 · Lutein · neutral · Facebook ↗
      Notes that lutein, a carotenoid found in kale, builds up in the retina and brain, helping to protect against macular degeneration and is linked to faster cognitive processing and better fluid intelligence.
    • 19 Jun 2026 · neutral · Facebook ↗
      Zeaxanthin may improve cognition, even in younger adults. It accumulates in the retina, where it helps neutralize light-driven oxidative damage linked to macular degeneration risk, and also accumulates in the brain, where higher blood levels are associated with better fluid and crystallized intelligence.
    • 19 Jun 2026 · Lutein · neutral · Facebook ↗
      Lutein may improve cognition, even in younger adults. It accumulates in the retina, where it helps neutralize light-driven oxidative damage linked to macular degeneration risk, and also accumulates in the brain, where higher blood levels are associated with better fluid and crystallized intelligence.
    • 5 Feb 2026 · neutral · Facebook ↗
      Zeaxanthin directly supports both vision and cognition in ways we can measure. Clinical trials show that supplementing it reduces risk of age-related macular degeneration and protects retinal function.
    • 5 Feb 2026 · Lutein · neutral · Facebook ↗
      Lutein directly supports both vision and cognition in ways we can measure. Clinical trials show that supplementing it reduces risk of age-related macular degeneration and protects retinal function.
    • 31 Oct 2025 · Lutein · neutral · Facebook ↗
      Lutein is a carotenoid essential for eye health and protection against age-related macular degeneration. It also accumulates in the brain, where it’s been shown to improve cognition in older adults.
    • 5 Aug 2025 · stopped · Podcast ↗
      Is no longer taking zeaxanthin.
    • 5 Aug 2025 · Lutein · stopped · Podcast ↗
      Is no longer taking lutein.
    • 6 May 2025 · uses · Facebook ↗
      Rhonda's current supplement routine includes Lutein & zeaxanthin.
    • 6 May 2025 · Lutein · uses · Facebook ↗
      Rhonda's current supplement routine includes Lutein & zeaxanthin.
    • 14 Apr 2025 · Lutein · neutral · Instagram ↗
      Mentions that the multivitamin used in the study contained lutein, which is known to accumulate in the brain and retina and influence cognitive and visual function.
  • Thomas DeLauer · Zeaxanthin · recommends
    • 25 Aug 2026 · recommends · YouTube ↗
      Highlights zeaxanthin as showing the strongest association with lower sleep disorder risk and recommends a dose of 4 mg, especially for those with high screen exposure, as it filters blue light at the retina level.
    • 25 Aug 2026 · Lutein · recommends · YouTube ↗
      Highlights lutein as showing the strongest association with lower sleep disorder risk and recommends a dose of 20 mg, especially for those with high screen exposure, as it filters blue light at the retina level.
    • 10 May 2026 · recommends · YouTube ↗
      Recommends zeaxanthin, found in eggs, as a carotenoid that accumulates in the brain and functions as an antioxidant, protecting neurons from inflammatory and oxidative damage.
    • 10 May 2026 · Lutein · recommends · YouTube ↗
      Recommends lutein, found in eggs, as a carotenoid that accumulates in the brain and functions as an antioxidant, protecting neurons from inflammatory and oxidative damage.
    • 29 Dec 2024 · Lutein · neutral · YouTube ↗
      Notes that lutein is beneficial for eye health and that studies have shown a correlation between higher lutein intake and less cognitive decline.
    • 29 Nov 2024 · Lutein · recommends · YouTube ↗
      Recommends lutein, found in eggs, for both long-term and short-term memory improvement.
    • 18 Oct 2024 · Lutein · neutral · YouTube ↗
      Explains that lutein, often touted for eye health, also accumulates in the brain and is a powerful antioxidant for driving down reactive oxygen species.
    • 12 Jul 2024 · neutral · YouTube ↗
      Notes that eggs contain zeaxanthin, which is tremendous for the eyes.
    • 12 Jul 2024 · Lutein · recommends · YouTube ↗
      Recommends lutein, specifically the FloraGLO form, for its benefits in reducing visceral fat, improving body composition, and positively impacting cardiometabolic health.
    • 26 Apr 2024 · Lutein · warns · YouTube ↗
      States that lutein might be one of the most potent cardiometabolic things one could take, citing research showing a significant difference in the risk of cardiovascular disease, heart attacks, stroke, and metabolic syndrome with higher lutein levels.
    • 16 Dec 2023 · neutral · YouTube ↗
      Notes that zeaxanthin, a carotenoid, is good for eye health and accumulates in the brain, being associated with improved cognition.
    • 16 Dec 2023 · Lutein · neutral · YouTube ↗
      Notes that lutein, a carotenoid, is good for eye health and accumulates in the brain, being associated with improved cognition.
    • 28 Nov 2023 · Lutein · recommends · YouTube ↗
      Recommends lutein as an inexpensive antioxidant, particularly good for the eyes, and notes it can be found in yellow bell pepper and eggs.
    • 27 Aug 2023 · Lutein · neutral · YouTube ↗
      Notes that avocados increased the body's lutein levels, a powerful free radical scavenger, which likely contributed to the reduction in oxidized LDL.
  • Dave Asprey · Zeaxanthin · recommends
    • 2 Jul 2026 · recommends · Facebook ↗
      Recommends getting nutrients like zeaxanthin from real food or Vision 101 for eyesight.
    • 2 Jul 2026 · Lutein · recommends · Facebook ↗
      Recommends getting nutrients like lutein from real food or Vision 101 for eyesight.
    • 7 Dec 2024 · recommends · YouTube ↗
      Recommends zeaxanthin, an antioxidant related to lutein, for improving eyesight.
    • 7 Dec 2024 · Lutein · recommends · YouTube ↗
      Recommends lutein, an antioxidant stored in the retina, which acts like natural sunglasses and helps the body handle blue light.
    • 3 Aug 2024 · Lutein · recommends · YouTube ↗
      Recommends supplements like lutein and astaxanthin, which are scientifically shown to improve eye resilience and ability to see.
    • 26 Apr 2022 · Lutein · recommends · YouTube ↗
      Mentions great studies on lutein for vision and recommends looking at vision formulas that contain it.
    • 7 Apr 2022 · uses · YouTube ↗
      Mentions zeaxanthin as an important plant pigment that covers the fovea and macula in the eyes, absorbing 60% of blue light in a healthy eye. He notes that age-related macular degeneration is often linked to a lack of these nutrients and too much blue light.
    • 7 Apr 2022 · Lutein · uses · YouTube ↗
      Mentions lutein as an important plant pigment that covers the fovea and macula in the eyes, absorbing 60% of blue light in a healthy eye. He notes that age-related macular degeneration is often linked to a lack of these nutrients and too much blue light.
    • 8 Dec 2019 · Lutein · uses · YouTube ↗
      Dave Asprey takes lutein, which is also made by bacillus indicus HU36, for eye health.
    • 8 Dec 2019 · Lutein · uses · YouTube ↗
      Takes massive doses of astaxanthin, lutein, and other protective things when flying to combat increased cosmic radiation and biological stress.
  • Dr. Mark Hyman · Lutein · neutral
    • 17 Jun 2026 · neutral · YouTube ↗
      States that lutein, a carotenoid, is concentrated in the macula and protects the eye from blue light and also protects the retina and brain.
    • 17 Jun 2026 · Zeaxanthin · neutral · YouTube ↗
      States that zeaxanthin, a carotenoid, is concentrated in the macula and protects the eye from blue light and also protects the retina and brain.
    • 14 Jun 2024 · neutral · YouTube ↗
      Green leafy vegetables contain lutein, which is great for eyes.
    • 19 Jan 2024 · recommends · YouTube ↗
      Recommends lutein-rich foods as important antioxidants and anti-inflammatory compounds.
    • 21 Dec 2022 · neutral · YouTube ↗
      Notes that lutein was among the compounds identified to regulate inflammation in a clinical trial.
    • 25 Jul 2018 · recommends · YouTube ↗
      Believes that a lack of lutein from green vegetables is a factor driving Alzheimer's and dementia.
  • Ben Greenfield · Zeaxanthin · uses
    • 18 Sep 2025 · uses · YouTube ↗
      Ben Greenfield's guest was taking zeaxanthin as part of their protocol.
    • 18 Sep 2025 · Lutein · uses · YouTube ↗
      Ben Greenfield's guest was taking lutein as part of their protocol.
    • 1 May 2025 · Lutein · uses · YouTube ↗
      Includes lutein in their Lumat blue product along with methylene blue, phycocyanin, riboflavin, green tea extract, and quercetin.
    • 13 Jan 2024 · Lutein · uses · YouTube ↗
      Ben says that the little bar he took has lutein in it.
    • 13 Sep 2023 · Lutein · neutral · YouTube ↗
      States that pigments like lutein and astaxanthin are photo modulators that pick up light in various wavelengths and translate them into photonic quantum energy sources.
    • 29 Apr 2023 · Lutein · neutral · YouTube ↗
      Mentions that pigments like lutein are photo modulators that pick up light in various wavelengths and translate them into photonic quantum energy sources.
    • 23 Feb 2023 · Lutein · uses · YouTube ↗
      Ben Greenfield's dog, Homer, who has a genetic predisposition to progressive retinal atrophy, is given lutein to support his eye structure health and scavenge free radicals.
    • 12 Dec 2019 · neutral · Podcast ↗
      Eating zeaxanthin-containing foods, such as corn, saffron, and leafy greens, may help the performance of our stem cells for organ regeneration.
    • 10 Dec 2019 · Lutein · uses · YouTube ↗
      Is loving Vaso Lutein, an oral supplement, for his vision and is hopeful it will help him get rid of glasses, especially when combined with eye exercises.
    • 17 Jan 2019 · recommends · Podcast ↗
      Mentions Zeaxanthin as a plant compound known to enhance vision.
    • 17 Jan 2019 · recommends · YouTube ↗
      Recommends zeaxanthin, found in dark leafy green vegetables, as a natural vision enhancer that ancestors consumed.
    • 17 Jan 2019 · Lutein · recommends · YouTube ↗
      Recommends lutein, found in dark leafy green vegetables, as a natural vision enhancer that ancestors consumed.
    • 22 Apr 2015 · recommends · YouTube ↗
      Ben Greenfield recommends zeaxanthin as a nutrient that is really important for the retina and vision, noting that dark leafy greens and egg yolks are good sources.
    • 22 Apr 2015 · Lutein · recommends · YouTube ↗
      Ben Greenfield recommends lutein as a nutrient that is really important for the retina and vision, noting that dark leafy greens and egg yolks are good sources.
  • Andrew Huberman · Lutein · recommends
    • 24 Apr 2025 · recommends · Podcast ↗
      Discusses lutein as a supplement for maintaining long-term eye health.
    • 24 Apr 2025 · recommends · YouTube ↗
      Notes that supplementing with lutein can help offset some detrimental effects of age-related macular degeneration, but only for individuals with moderate to severe conditions, as studies did not show significant improvement for those with normal vision or low-degree degeneration.
    • 26 Jun 2023 · recommends · YouTube ↗
      Recommends lutein as part of the AREDS2 supplementation for slowing the progression of dry macular degeneration.
    • 26 Jun 2023 · Zeaxanthin · recommends · YouTube ↗
      Recommends zeaxanthin as part of the AREDS2 supplementation for slowing the progression of dry macular degeneration.
    • 27 Apr 2023 · warns · YouTube ↗
      Discusses lutein as a supplement that can potentially help with age-related macular degeneration, noting that the data are still emerging. He mentions that some people report enhanced vision from taking lutein at 20 milligrams per day, and studies have explored dosages of 10 to 20 milligrams per day.
    • 27 Apr 2023 · Zeaxanthin · warns · YouTube ↗
      Mentions zeaxanthin as a compound that, along with lutein and astaxanthin, is being explored for its potential to help with age-related macular degeneration, though he notes that the data are still emerging.
    • 21 Jun 2021 · neutral · YouTube ↗
      Corrects a previous misstatement, clarifying that Lutein (L-U-T-E-I-N) is the molecule that may help offset moderate to severe age-related macular degeneration and potential vision loss as one gets older.
    • 14 Jun 2021 · neutral · Podcast ↗
      Mentions Lutein as a compound that may assist in supporting visual health and possibly improve vision.
    • 14 Jun 2021 · recommends · YouTube ↗
      Discusses a study showing that lutein supplementation can help offset detrimental effects of age-related macular degeneration, but only for individuals with moderate to severe conditions, not for those with normal vision or low-degree macular degeneration.
    • 14 Jun 2021 · Zeaxanthin · neutral · Podcast ↗
      Mentions Zeaxanthine as a compound that may assist in supporting visual health and possibly improve vision.
    • 14 Jun 2021 · Zeaxanthin · neutral · YouTube ↗
      Mentions that Zeaxanthin has been shown to offset some of the disruption in vision that occurs with aging.
    • Date not recorded · neutral · Website ↗
      Discusses lutein as a molecule in many vision supplements, noting that studies show it can help offset detrimental effects of age-related macular degeneration, but only for individuals with moderate to severe conditions.
    • Date not recorded · Zeaxanthin · neutral · Website ↗
      Notes that supplementing with zeaxanthin can be beneficial for slowing the progression of age-related macular degeneration, though the degree of offset is slight but robust. He personally is not taking zeaxanthin at this time.
  • Peter Attia · Lutein · neutral
    • 6 Sep 2024 · neutral · YouTube ↗
      Mentions that there is mixed, weak evidence suggesting lutein and zeaxanthin might be protective for cataract, as they are also antioxidants.
  • Bryan Johnson · Lutein · stopped
    • 26 Jun 2023 · stopped · YouTube ↗
      Stopped taking lutein because it caused his skin to turn a little yellow after taking 20 milligrams a day for about a year.

RAL Summary

Members OnlyTier 2 for Eye Health

Both ingredients are at studied doses, and several pooled analyses, the largest covering 85,321 people, show lutein and zeaxanthin improve eye pigment, sharpness of vision and contrast sensitivity [4][1][2]. The tier reflects strong study support plus very positive buyer ratings.

Where the evidence disagrees: 16 of the 81 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Eyes and vision

Combine with: To enhance the benefits of Lutein and Zeaxanthin for comprehensive eye health, consider combining them with Omega-3 fatty acids (especially DHA), which are vital for retinal structure and function. Antioxidants like Vitamin C and E can offer additional protection against oxidative stress in the eyes. Zinc is also beneficial as it plays a role in eye health and the metabolism of other nutrients. For broader antioxidant support and reduced eye fatigue, Astaxanthin can be a powerful addition. Lastly, Bilberry extract is often used to support vision, particularly in low light conditions.

Possible side effects: No major side effects reported. In long term follow-up, lutein and zeaxanthin did not significantly raise lung cancer risk, unlike beta carotene.

Supplement Facts

Lutein 20 mg · Zeaxanthin 1 mg
Supplement Facts
Serving Size 1 Softgel
Servings Per Container 120
Amount Per Serving% Daily Value
Lutein (from Marigold Extract) (Tagetes erecta)(flower)20 mg†
Zeaxanthin (from Marigold Extract) (Tagetes erecta)(flower)1 mg†
† Daily Value not established.

Directions: Take 1 softgel daily, with food. Best when taken as directed by a qualified healthcare professional.

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Our articles on this subject

Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.