PreserVision ® AREDS 2 Formula + Multivitamin Supplement Soft Gels Review

PreserVision is presented as the first leading brand to combine the AREDS2 study formula with other essential vitamins and minerals typically found in daily multivitamins. This convenient 2-in-1 formula combines the benefits of PreserVision AREDS 2 Formula plus a daily multivitamin, making it simpler to take supplements by reducing the number of pills taken each day. PreserVision AREDS 2 Formula + Multivitamin is beta carotene-free and contains a high level of Vitamin D to support the needs of older adults. The page explains that the product was created in response to consumer feedback and data, which showed that 90 percent of participants in the AREDS2 clinical study who took an AREDS supplement also took a daily multivitamin. PreserVision is described as the #1 doctor-recommended eye vitamin brand, based on two major clinical studies known as AREDS and AREDS2. The page notes that the National Eye Institute recommends people with moderate to advanced age-related macular degeneration take a supplement with a specific combination of antioxidants and zinc based on the AREDS2 study. The product listing states that PreserVision AREDS 2 + Multivitamins contain lutein, zeaxanthin, zinc, copper, vitamin C, and vitamin E to match the nutrient formula recommended by the National Eye Institute based on the Age Related Eye Disease Study 2, which helps reduce the risk of moderate to advanced AMD progression in adults aged 50 and over, while added multivitamins support overall wellness. The page describes PreserVision as based on 20 years of clinical studies conducted by the NEI and calls it the most studied eye vitamin brand based on AREDS and AREDS2 clinical studies. The suggested use is to take 2 soft gels daily with food, 1 in the morning and 1 in the evening. The page also says this supplement for adults provides essential vitamins with high-quality, clinically proven ingredients. The product is sold by Bausch + Lomb Eye Care, described as eye experts since 1853, offering trusted products from eye vitamins and supplements to lubricant eye drops and lens care. A wheel of ingredients image is provided for the AREDS 2 formula. The offer shows a price of $30.99 for a one-time purchase, or $29.49 with subscription, with delivery options every 50, 60, or 100 days, and a note that a SightMatters coupon code can save more on subscription orders. The listing is for the 100 count soft gels format.

Product Focus: Eye HealthAlso covers:DigestionBrainRanked among:Multivitamins
Tier ⓘ
Tier 2 · Rank 3
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 3 within Tier 2 for Eye Health; 3 of 39 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
88 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
93% of 56,908
Biohacker Mentions
10 of 10
Cost per month
$19

Study, Trial or Testing Result Summary

Members Only331 human studies · 170 improved

10 of these 331 human studies gave the ingredient by drip, injection or inhaler, not by mouth.

331 human studies170 improved104 no effect1,775,658 people studied

This is an eye formula for people with macular degeneration, the age-related loss of central vision, with a multivitamin added. Zeaxanthin and lutein are near the studied amounts. Reviews of many trials found they raise protective pigment in the eye and improve sharpness and contrast of vision [1][2][3]. One review ranked them second for sharper vision in macular degeneration [4]. In a large five-year trial, adding them did not clearly slow progression in the main analysis [5], but later analyses and a ten-year follow-up suggested about 10 percent lower risk of advanced disease [6][7]. Zinc, copper and vitamin C are at full studied amounts. Combined with antioxidants, they slowed progression to advanced macular degeneration and reduced vision loss [8][9][10]. Vitamin C alone did not prevent the disease [11]. Vitamin E alone did not protect vision and may slightly raise the risk of late disease [11]. Vitamin D, the B vitamins, magnesium and selenium are well below the doses studied, so their study results do not apply here. For example, B vitamins cut macular degeneration only at much higher doses [12]. Animal and cell studies are never counted.

See all 331 studies →Hide the studies

Review Totals and Summary

Members Only56,908 reviews · 93% positive
56,908 reviews · Amazon 56,638 · Shop.preservision 224 · PreserVision Shop 46
93% positive4% neutral3% negative

Customer feedback is mixed in tone. It differs sharply by source: retailer pages are very positive, and Drugs.com is much more negative. On retailer sites such as Walmart, Sam's Club and Safeway, buyers often say an eye doctor recommended it, especially after a cataract surgery or an AMD diagnosis. Many describe taking it for years, sometimes a decade, and say their vision or diagnosis has stayed stable. Several credit it with slowing macular degeneration, though they admit they can't prove it. Others say they trust the brand and will keep buying it "just in case." Shoppers also like the value of large bottle counts and say the soft gels are easy to swallow. The "mini" size is a frequent reason people choose the standard eye-only formula. Even so, some buyers say the multivitamin version is bigger. One reviewer said it was too big to swallow and went back to the smaller eye-only product. Another, who has eosinophilic esophagitis, returned it because of the size and possibly the coating. People with swallowing trouble often praise the chewable version instead. The negative themes come mostly from Drugs.com, where the average is about 2.8 out of 10 and roughly three-quarters of reviewers report a negative experience. The most common complaints are digestive. They include nausea and constipation, and some reviewers link the nausea to the gel coating. One reviewer said switching to the chewables ended it. Several reviewers report sleep disturbance, which they attribute to the "red pill." Others mention a change in the gel's color or formulation and ask the company to rethink the formula. Some people simply stop after reading others' complaints. A few also express skepticism, since they can't tell whether it is working. They note that the benefit is long-term risk reduction, not a noticeable feeling or improved sight. Some buyers say they notice when they skip doses. A few report feeling more alert or better overall after several weeks, which fits the added multivitamin. Overall, users who tolerate it tend to be loyal, long-term and doctor-guided. Users who have stomach upset, trouble with pill size or sleep problems tend to drop it or switch to the eye-only, mini or chewable versions.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Zinc is the main ingredient here, and nine of the ten panelists spoke about it, while the tenth only said lutein has human evidence. Most of them recommend or use zinc: reasons include testosterone and prostate health, gut lining (as zinc carnosine), wound healing around surgery, helping the body absorb vitamin C, skin care, and sleep and blood vessel support. One panelist takes 15 mg in the morning for longevity, one pairs it with vitamin C for fall and winter, and another pairs it with magnesium. One panelist warns that overshooting zinc can lead to a copper deficiency, and his own surgery plan uses zinc for one week before and two weeks after the procedure. Vitamin D and magnesium, smaller ingredients in this product, drew the most comments from the panel, mainly for general health and sleep.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Zinc · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
    • 2 Nov 2026 · Vitamin D · warns · Facebook ↗
      Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
    • 31 Oct 2026 · Vitamin K · recommends · Podcast ↗
      Discusses foods that contain Vitamin K2.
    • 30 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
    • 30 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
    • 30 Oct 2026 · Magnesium · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
    • 25 Oct 2026 · Vitamin D · recommends · X ↗
      Recommends increasing vitamin D to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Vitamin K · recommends · YouTube ↗
      Recommends taking 40 to 45 milligrams of vitamin K2 daily for osteoporosis, citing a study from Japan with great results.
    • 25 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · Magnesium · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
  • Andrew Huberman · Zinc · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 22 Oct 2026 · Magnesium · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 19 Oct 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 21 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 14 Sep 2026 · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 17 Aug 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 7 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 7 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
  • Ben Greenfield · Zinc · warns
    • 29 Oct 2026 · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Copper · neutral · YouTube ↗
      Mentions that overshooting zinc can lead to a copper deficiency, highlighting the interplay between these elements.
    • 29 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Vitamin E · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 29 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 22 Oct 2026 · Magnesium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · Magnesium · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · Magnesium · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Vitamin K · neutral · Facebook ↗
      Discusses vitamin K2, specifically the menaquinone forms, as crucial for arterial health and notes that it breaks down into MK-4 and MK-7.
    • 15 Oct 2026 · Vitamin K · uses · YouTube ↗
      Explains that gut bacteria liberate K from the diet or make the K needed, and that poor absorption of vitamin K due to bacterial imbalances is linked to heart disease.
  • Thomas DeLauer · Zinc · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 28 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 24 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 23 Oct 2026 · Vitamin D · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 20 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 8 Oct 2026 · Magnesium · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 8 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
    • 6 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 6 Oct 2026 · Vitamin D · uses · YouTube ↗
      Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
  • Dave Asprey · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 1 Nov 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 31 Oct 2026 · Magnesium · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 25 Oct 2026 · Magnesium · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 9 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · Vitamin D · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin E · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
    • 7 Oct 2026 · Vitamin K · recommends · YouTube ↗
      Recommends taking vitamin K2 with vitamin D to keep calcium in the bones, and suggests kids also take it for stronger bones.
    • 7 Oct 2026 · Vitamin K · recommends · YouTube ↗
      Recommends Vitamin K2, stating it supports healthy calcium metabolism.
  • Dr. Mark Hyman · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
    • 1 Nov 2026 · Magnesium · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 26 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 21 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
    • 14 Oct 2026 · Magnesium · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 8 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
    • 7 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 7 Oct 2026 · Vitamin D · neutral · Podcast ↗
      Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
  • Dr. Rhonda Patrick · Zinc · recommends
    • 29 Sep 2026 · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 29 Oct 2026 · Magnesium · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · Magnesium · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 5 Oct 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 30 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 29 Sep 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 28 Sep 2026 · Magnesium · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 28 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 28 Sep 2026 · Folate · recommends · YouTube ↗
      Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
    • 24 Sep 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
    • 2 Sep 2026 · Magnesium · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 25 Aug 2026 · Zeaxanthin · neutral · Facebook ↗
      Zeaxanthin may be among the most evidence-backed carotenoids for longevity. It accumulates in the brain, where higher levels are associated with greater crystallized intelligence, and supplementation can improve some measures of cognitive function. Evidence also suggests it may slow progression to advanced macular degeneration in high-risk individuals.
    • 25 Aug 2026 · Lutein · neutral · Facebook ↗
      Lutein may be among the most evidence-backed carotenoids for longevity. It accumulates in the brain, where higher levels are associated with greater crystallized intelligence, and supplementation can improve some measures of cognitive function. Evidence also suggests it may slow progression to advanced macular degeneration in high-risk individuals.
  • Siim Land · Lutein · neutral
    • 6 Sep 2026 · neutral · X ↗
      Notes that Lutein is one of several supplements with human evidence.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 25 Oct 2026 · Magnesium · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 24 Oct 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 14 Oct 2026 · Copper · neutral · Instagram ↗
      Mentions that copper is a mineral necessary for making collagen.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 9 Oct 2026 · Vitamin K · neutral · Instagram ↗
      Notes that Vitamin K2 helps activate proteins involved in bone mineralization and calcium regulation.
    • 8 Oct 2026 · Vitamin K · neutral · YouTube ↗
      Mentions that prunes contain vitamin K, which is a factor in their ability to help with bone density.
    • 7 Oct 2026 · Magnesium · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 7 Oct 2026 · Vitamin K · recommends · Instagram ↗
      Recommends Vitamin K2 for bone health and calcium metabolism, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · Magnesium · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
  • Bryan Johnson · Zinc · uses
    • 4 May 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 22 Oct 2026 · Vitamin K · uses · X ↗
      Takes 90 mcg of Vitamin K2 in the morning for general health.
    • 22 Oct 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 22 Oct 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 3 Jul 2026 · Vitamin D · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · Vitamin K · uses · X ↗
      Takes 100 mcg of Vitamin K2 in the morning for longevity.
    • 4 May 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 4 May 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · Vitamin K · uses · X ↗
      He takes 100 mcg of Vitamin K2 in the morning for general health.
    • 2 May 2026 · Vitamin D · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 2 May 2026 · Magnesium · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
  • Peter Attia · Zinc · recommends
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 1 Jun 2026 · Magnesium · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · Magnesium · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 4 Jan 2026 · Vitamin D · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 17 Nov 2025 · Iodine · warns · Podcast ↗
      Discusses the dangers of supplementing with high levels of iodine.
    • 16 Nov 2025 · Vitamin D · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 16 Nov 2025 · Iodine · warns · YouTube ↗
      Warns that high-dose iodine supplementation carries a risk of autoimmune thyroid disease, citing increased incidence in Japan due to higher dietary iodine intake.
    • 16 Nov 2025 · Selenium · neutral · YouTube ↗
      Notes that several studies show patients taking selenium can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 15 Sep 2025 · Magnesium · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 6 Aug 2025 · Vitamin D · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 3 Aug 2025 · Vitamin D · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · Vitamin D · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 10 Jul 2025 · Vitamin D · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
    • 9 Jul 2025 · Magnesium · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.

RAL Summary

Members OnlyTier 2 for Eye Health

Several reviews of trials found that lutein and zeaxanthin improve sharpness of vision in macular degeneration, the largest covering 85,321 people [4][2]. The full-dose zinc and antioxidant formula slowed progression to advanced disease [8], and 93% of 56,908 reviews are positive.

Where the evidence disagrees: 104 of the 331 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Eyes and vision, Digestive system, Nervous system

Combine with: For its intended vision purpose, PreserVision pairs well with omega-3 fatty acids (EPA/DHA) for retinal and dry-eye support, and with a diet rich in leafy greens. Saffron extract and bilberry or astaxanthin may add further macular and antioxidant support. Take it with a meal containing some fat to improve absorption of lutein and zeaxanthin and to reduce zinc-related stomach upset. If you want post-meal upper-abdominal comfort, look at a separate digestive product such as broad-spectrum digestive enzymes, ginger, peppermint oil, or gentian and other digestive bitters, and speak with a healthcare provider if symptoms persist.

Possible side effects: Reviewers report nausea, constipation and sleep disturbance, and some find the soft gels too large to swallow. In studies, vitamin E alone may slightly raise the risk of late macular degeneration, and high-dose B vitamins were linked to more cataract surgery.

Supplement Facts

Vitamin C 250 mg · Vitamin D 7.5 mcg · Vitamin E 90 mg
Supplement Facts
Serving Size 1 Soft Gel
Amount Per Serving% Daily Value
Calories5
Total Fat0.5 g
Saturated Fat0.5 g
Total Carbohydrate1 g
Protein1 g
Vitamin C250 mg
Vitamin D7.5 mcg
Vitamin E90 mg
Vitamin K15 mcg
Thiamin0.75 mg
Riboflavin0.85 mg
Niacin10 mg
Vitamin B61 mg
Folate333 mcg DFE
Vitamin B1212.5 mcg
Biotin15 mcg
Pantothenic Acid5 mg
Iodine75 mcg
Magnesium50 mg
Zinc40 mg
Selenium9.5 mcg
Copper1 mg
Manganese1 mg
Chromium25 mcg
Molybdenum22.5 mcg
Lutein5 mg†
Zeaxanthin1 mg†
† Daily Value not established.

Directions: Take 2 soft gels daily with food; 1 in the morning, 1 in the evening.

Barcode (UPC) 324208698648 · Label source: Reverseagelab · Report a label change

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Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.