CS Health Vitalica Plus Extra Strength Physicians' Formula Review
Vitalica Plus Extra Strength from Physicians Formula is presented on this page as a sulforaphane supplement that the page says has twice the nutritional value of the regular Vitalica Plus. The page says the product converts to sulforaphane in the body. Sulforaphane is described as activating Phase II enzymes, helping to protect DNA from free radicals, and promoting immune system health. The listed benefits include support for antioxidant activity, a role as a detoxification agent, a concentration described as 1000 times more concentrated than broccoli, and a patented ingredient. The page states that the Physicians Formula label is not to be misconstrued as having a therapeutic nature. It explains that doctor customers and practitioners suggested a product with higher potency than the regular capsules, and that each capsule is twice the potency of a Vitalica Plus capsule. The product is sold with a Default Title option and a quantity selector, and the page advertises a 100% money back guarantee. A separate 30-day no hassle money back guarantee offers a full refund if the buyer does not like the product. The detoxification section explains that the body processes outside chemicals in two phases. In Phase 1, detoxifying enzymes begin processing metabolites. In Phase 2, enzymes process metabolites so they become dissolved and can be excreted. Sulforaphane is described as increasing production of Phase 2 enzymes. The page says Vitalica Plus activates Phase II enzymes, helps inactivate free radicals, and promotes immune system health. The proprietary ingredient section links sulforaphane to the body converting glucoraphanin into sulforaphane. It cites research published in 1997 in the Proceedings of the National Academy of Sciences stating that broccoli sprouts provide 73 milligrams of sulforaphane glucosinolate per 1-ounce serving. It says the greatest concentration of the precursor is found in broccoli seed, and that a particular variety was developed without genetic modification over a twelve year period. Three highlighted features are listed: full range detoxification that boosts liver detoxification enzymes, immune system support through phase II enzymes, and cell rejuvenation that helps maintain cellular health and promotes healthy cell replication.
Study, Trial or Testing Result Summary
Members OnlyHuman studies
This product contains one listed ingredient, broccoli seed raffinate, at 600 milligrams a day. The store describes it as enzyme activated broccoli that supplies glucoraphanin, which the body converts to sulforaphane. Whether 600 milligrams matches any dose used in research is unclear, because no human studies of this ingredient for joint health were found in our review. That means there are no trials showing that it improves joint pain, stiffness, mobility or any other joint outcome, and none showing that it fails to help. The evidence is simply missing rather than negative. The product has 11 ratings, about three quarters of them positive, but that is too few to draw firm conclusions. Buyers who wrote comments described long term use for general health and antioxidant support, not joint health in particular. Anyone choosing this product for joints should know that its use for this goal rests on general ideas about sulforaphane rather than on tested results in people. Until human studies on joint health are done, its benefit for this goal remains unproven. Animal and cell studies are never counted.
Review Totals and Summary
Members Only11 reviews · 75% positive
The CS Health shop shows 11 ratings in total for this product, and the themes below come from the five written reviews that could be read on its page. Praise is the only thing the written reviews contain. All five come from verified buyers, and none includes a complaint. The comments are short and enthusiastic. One buyer wrote only "Loved it," with no detail. Another, Sayla H., left two reviews: one titled "Life saver" from December 2023 and one titled "Broccoli seeds rock my world!" from March 2023, and the store replied to the second with "Thank you!" George K. called it a great product and described it as the main vitamin for the body's own antioxidant defence and for good health. Suzanne M. said she has used it for several years. Several themes recur. The first is loyalty over time, with at least one reviewer describing years of use. The second is the sense that the product supports antioxidant and general health. The third is appreciation for the broccoli-based sulforaphane story, which shows in the "Broccoli seeds" title. The fourth is satisfaction with the company itself: Suzanne M. praised the information provided on its website and said her order was delivered promptly. On complaints, there are none in the written text. This sits oddly with the overall rating of 4 out of 5 across 11 ratings. Because all five written reviews are positive, the text does not explain why the average is below 5. The page shows no star breakdown, so the share of lower ratings cannot be measured, and any lower ratings appear to have been left without written comments. As for who it seems to suit, the reviewers who wrote in appear to be people taking it long term for general health and antioxidant support, who value a product built on broccoli-derived sulforaphane and like having detailed information from the company. Nothing in the reviews points to a particular age group, condition or use case beyond that. On taste, form and value, the reviews say little. Reviewers talk about the product's purpose rather than its dose, taste, capsule size or how quickly they noticed any effect. Nothing is said about price or value for money, so the written feedback gives little practical detail on daily use. Helpful votes on the reviews are small, with counts of 2, 1, 3 and 3 shown on the page. Only capsule feedback is relevant here, and nothing on the page was identified as covering gummies, powder or any other form, so no reviews had to be left out on that basis. Overall, buyers who wrote reviews appear satisfied and describe long-term use, but the text is brief and offers few specifics beyond general praise for the product, the website information and the delivery. Only five written reviews were readable, so this summary reflects those five rather than all 11 ratings.
Biohacker Summary
Members Only9 of 10 recommend it
Broccoli is the main ingredient here, and all ten panelists spoke about it; most recommend or use it, mainly for sulforaphane, which they link to detox pathways and antioxidant defenses, and for fiber. Sprouts are the favorite form, with several saying they hold up to 100 times more sulforaphane than mature broccoli, while others eat steamed or raw broccoli, take seed or sprout extracts, or use it in a daily vegetable breakfast. For pairing, three suggest mustard seed or mustard powder, one reporting almost five times more sulforaphane metabolites from 200 grams of cooked broccoli with one gram of mustard powder, and two advise chopping it and letting it sit for 10 to 40 minutes before cooking. Cautions came from three panelists: one says most broccoli supplements contain a precursor that may be absorbed poorly, one says many sprout seeds fail to make sulforaphane and that adult broccoli can affect the thyroid and gut, and one dislikes the taste. The same panelist who called sprouts a waste of time says he takes broccoli extracts because he finds them very useful.
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Dr. Eric Berg · Broccoli · recommends
- Dr. Eric Berg recommends pairing broccoli with mustard seeds to boost beneficial plant compounds.
- Suggests pairing broccoli with mustard for better absorption.
- Recommends broccoli sprouts for supporting heavy metal detoxification.
- Dr. Eric Berg suggests that broccoli sprouts are the best food for your liver.
- Notes that broccoli has a glycemic index of basically one.
- Recommends consuming broccoli with mustard to enhance sulforaphane.
- Recommends broccoli sprouts as one of ten foods that help lose belly fat.
- Recommends broccoli as a quercetin-rich food that supports a healthy inflammatory response and helps protect cells from oxidative stress for kidney health.
- Notes that broccoli has a glycemic index of one.
- Uses broccoli as an example, stating that if it can help prevent a disease, it would be considered a drug by the legal definition.
Dr. Rhonda Patrick · Broccoli · recommends
- States that sulforaphane, found in broccoli, activates enzymes that make plastic-associated chemicals water soluble for excretion.
- Broccoli sprout extracts increased excretion of airborne carcinogens like benzene by about 60% within 24 hours.
- States that broccoli sprouts are a concentrated source of the sulforaphane precursor glucoraphanin and are one of the best sources for boosting cellular defenses.
- Sulforaphane, found in especially high amounts in broccoli sprouts, activates NRF2, which binds to toxins and makes them water-soluble for excretion.
- Mentions that sulforaphane-rich broccoli sprout extracts boosted excretion of airborne carcinogens like benzene and acrolein by ~60% within just 24 hours.
- Recommends daily intake of sulforaphane-rich foods like broccoli, noting that human studies show it reduces oxidative DNA damage and boosts detoxification.
- Recommends broccoli sprouts as the best source of sulforaphane, containing about 100 times more of its precursor than mature broccoli, and suggests consuming 45 to 100 grams a day.
- States that broccoli sprouts are a great source of sulforaphane precursor.
- Recommends consuming freshly crushed broccoli sprouts for the best effect, as they contain glucoraphanin which converts into sulforaphane.
- For those aiming to increase sulforaphane intake, dietary sources like broccoli sprouts are excellent, providing some of the highest concentrations of glucoraphanin.
Thomas DeLauer · Broccoli · recommends
- Recommends eating steamed broccoli with brown mustard powder to activate sulforaphane, noting that 200g of cooked broccoli with one gram of mustard powder increased sulforaphane metabolites almost 5x, acting as a master switch for detox pathways.
- Eats vegetables like broccoli, emphasizing chewing through its cellular structure rather than consuming just juices.
- Recommends broccoli sprouts for lung health, as sulforaphane activates Nrf2 and can be up to 100 times more potent than mature broccoli.
- Includes broccoli for its sulforaphane, which activates Nrf2 to drive antioxidant and detox pathways, advising to chop and let it sit for ten minutes before cooking.
- Recommends consuming a handful of raw broccoli sprouts, which contain 100 times more sulforaphane than mature broccoli, to activate the NRF2 pathway and help excrete chemicals like BPAs and phthalates.
- Usually eats steak, broccoli, and blueberries for dinner.
- Recommends broccoli sprouts for detoxing plastic chemicals like BPA and BPS, noting they have 100 times more glucoraphanin, the precursor to sulforaphane, than mature broccoli.
- Recommends broccoli for its sulforaphane precursors and fiber, acknowledging its unique qualities despite not being extremely nutrient-dense.
- Recommends broccoli sprouts for NRF2 activation, which increases glutathione synthesis and phase 2 detoxification.
- Recommends broccoli as a source of soluble fiber for keto.
Siim Land · Broccoli · uses
- States that broccoli is one of the boring foods from which he gets most of his fiber.
- Lists broccoli as a food high in spermidine, providing 3 mg per 100g, which he consumes for longevity.
- Lists broccoli sprouts as a top food for sulforaphane, containing 30-100 mg/100g.
- Lists broccoli sprouts as a top food for sulforaphane, noting they contain 30-100 mg/100g.
- Recommends broccoli sprout extract as a component in a targeted detox for boosting NRF2 signaling, which is the natural endogenous antioxidant pathway signaling on a genetic level.
- Recommends broccoli as a food to hit the daily dose of polyphenols for longevity and anti-aging.
- Recommends having about 200g of broccoli with a bit of broccoli sprouts.
- Notes that Dave Pasco is stacking sulforaphane and myrosinase with a broccoli and cruciferous blend, implying redundancy.
- Includes broccoli in their diet for fiber.
- Consumes broccoli post-workout for an antioxidant and fiber boost.
Dave Asprey · Broccoli · recommends
- Mentions that the guys from Broccolite talked about sulfation and make a broccoli extract with good data for raising glutathione inside of cells and the rate of glucuronidation.
- States that broccoli sprouts are a waste of time because many seeds don't make sulforaphane, and it's a 'crap shoot' whether they will.
- Eats some broccoli.
- Takes broccoli extracts because he hates broccoli but finds it extremely useful.
- Dave Asprey explores why adult broccoli can block thyroid function and cause gut issues.
- Used to eat 2.5 pounds of broccoli in a day as a vegan and raw vegan, but no longer does so due to the presence of toxins and the impracticality of consuming such large quantities for benefit.
- Has noticed a massive difference from using Brock Elite, a broccoli extract containing sulforaphane activated by another chemical, which performs all three stages of detoxification.
- Recommends broccoli as a food with more fiber than oatmeal, advising to cook it to reduce negative effects on the thyroid.
- Warns that if one's gut bacteria produce a lot of sulfide, they should not eat broccoli, cabbage, or Brussels sprouts, as these foods contain sulfates that will increase sulfide production and cause inflammation.
- Mentions a study from China where a broccoli sprout beverage helped people clear toxins like benzenes quickly.
Dr. Mark Hyman · Broccoli · uses
- States he was using broccoli seed extract to stimulate the NRF2 pathway and open up detox.
- Recommends broccoli as a vegetable that contributes to fiber intake.
- Makes steamed broccoli with lemon, garlic, olive oil, salt, and pepper, advising not to overcook it to avoid mushiness.
- Recommends foods from the broccoli family, including broccoli, collards, kale, cabbage, and Brussels sprouts, as great foods that upregulate the body's own detoxification pathways.
- Notes that broccoli sprouts contain about a hundred times more glucoraphanin, the precursor to sulforaphane, than mature broccoli, and is trying to grow them.
- Recommends broccoli as a food that boosts the body's own detox enzymes like glutathione.
- Recommends broccoli sprouts as real longevity medicine.
- Used to sprout broccoli but no longer does due to being busy, instead opting for a sulforaphane supplement.
- Recommends 5-day-old broccoli sprouts as a huge NRF2 activator and the most bioavailable source of sulforaphane, but advises cycling them to prevent the body from shutting down the defense mechanism.
- States that broccoli sprouts are one of the most powerful foods for boosting glutathione and detoxification.
Ben Greenfield · Broccoli · warns
- Warns that most broccoli supplements do not contain active sulforaphane, but rather glucoraphanin, which has variable conversion rates in the gut, meaning users might absorb almost nothing.
- Warns that not all broccoli seeds contain glucoraphanin to produce sulforaphane, citing an experience where most sources they tested did not.
- Mentions broccoli sprouts as an example of a plant that, in large amounts, can cause oxidative stress, but in small amounts, can be beneficial.
- Ben's favorite sprouts are broccoli, due to their umami flavor and sulforaphane benefits.
- Used the "Broccoli & Friends" mix, a blend of high-germination broccoli, alfalfa, radish and clover sprouting seeds, with a glass mason jar sprouting method for 5 days.
- Recommends that broccoli, brussel sprouts, and cabbage be avoided or, if consumed, at least steamed or sautéed to neutralize some of the effect of glucosinolates, which can be converted into sulfide gas by microbes.
- Recommends avoiding broccoli and Brussels sprouts, or at least steaming or sautéing them, if one has a specific profile with high sulfide production and high fermenters, as they can exacerbate discomfort.
- Contrasts a ribeye steak with a plate of soaked and sprouted quinoa, fermented sourdough bread, sweet potato, and a broccoli sprout smoothie, suggesting the latter is survival food.
- States that broccoli is shown to decrease the risk of hearing loss.
- Recommends chopping broccoli into small pieces about 90 minutes prior to cooking.
Andrew Huberman · Broccoli · neutral
- Notes that broccoli sprouts have up to 100 times more sulfurophane than broccoli and activate glutathione in the brain.
- Mentions that broccoli is oddly a good source of protein.
- Suggests using steamed broccoli from the freezer in a chocolate smoothie because it has very little taste.
- Despises broccoli because he remembers his mother forcing him to eat it.
- Recommends broccoli sprouts, noting they have up to 100 times more sulforaphane than broccoli and are powerful activators of the Nrf2 pathway, which is involved in detoxification and glutathione production.
- Recommends eating broccoli to reduce vulnerability to endocrine or hormone disruption.
- Andrew Huberman mentions that Dr. Zuker despises broccoli because he remembers his mother forcing him to eat it, despite it being the same sensory experience for others who like it.
Peter Attia · Broccoli · recommends
- Recommends broccoli as a fibrous carbohydrate source, noting it is about one-third fiber.
- States that broccoli is about one-third fiber and is one of the foods he eats every day.
- Consumes quite a bit of broccoli as a source of fiber.
- Mentions that broccoli has not been linked with any real increased or decreased risk for developing prostate cancer in decent follow-up studies.
- Notes that products in grape skin, broccoli, and tomato have not been linked with any real increased or decreased risk for developing prostate cancer.
- Includes quite a bit of broccoli as a source of fiber in his diet.
Bryan Johnson · Broccoli · uses
- Uses broccoli and recommends letting it sit for 40 minutes after chopping before cooking to activate the enzyme myrosinase, which unlocks sulforaphane, a strong anti-cancer compound with potential sugar-lowering and detoxifying properties.
- Includes 250g of broccoli in his Super Veggie for antioxidants, bowel health, and fiber.
- Mentions broccoli as an ingredient in Bronco Max, which he uses.
- Includes over 300 grams of pureed broccoli in his daily 'Super Veggie' breakfast for its nutrient density.
- Uses broccoli in his Super Veggies.
RAL Summary
Members OnlyTier 4 for Joints and Mobility
It sits at the emerging tier because no human studies have tested broccoli seed raffinate for joint health and there are only 11 reviews, which is not enough to rank it higher.
- Emerging: not enough evidence to rank higher yet.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Musculoskeletal system
Combine with: For joint support, pair glucosamine and chondroitin with MSM for connective tissue and inflammation support, undenatured type II collagen or hydrolyzed collagen peptides for cartilage matrix support, and omega-3 fish oil (EPA/DHA) to help modulate joint inflammation. Curcumin (with piperine or in a phytosome form) and Boswellia serrata may add anti-inflammatory support. Vitamin D3 with K2 and magnesium support bone and cartilage health, and vitamin C supports collagen synthesis. If the broader goal is cellular aging support, add separate agents with actual evidence in that area, such as NMN or NR for NAD+ support, resveratrol or quercetin, CoQ10 or ubiquinol, and alpha-lipoic acid. Check with a physician first, especially when taking meds, or if you have a shellfish allergy, diabetes, or asthma, since glucosamine is often shellfish-derived and can interact with some medications.
Possible side effects: No major side effects reported.
Supplement Facts
Broccoli seed raffinate 600 mg
| Broccoli seed raffinate | 600 mg | † |
Other ingredients: Calcium Ascorbate, Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Tapioca Dextrin.
Directions: Directions: Take one capsule on an empty stomach, or 30 minutes after last meal, with water; or as directed by your health care practitioner.
Label source: NIH label database · Report a label change
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Graded November 3, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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