iMatchme Soursop Liquid Drops Review
The iMatchme Soursop Graviola Liquid Drop offers a potent and easily absorbable supplement designed for comprehensive cell support and regeneration, immune boosting, relaxation, and liver and sleep support. Derived from the Annona muricata, a small evergreen tree known scientifically as soursop, this product leverages the plant's rich nutrient profile and its long-standing use in traditional medicine to deliver a variety of health benefits. Each serving provides 1800mg of soursop graviola, formulated for high absorption to ensure maximum efficacy for overall health, well-being, and nutrient metabolism. This liquid supplement is specifically crafted to support the immune system, acting as a rich source of antioxidants that help protect the body's cells. Beyond immune health, it also aids in promoting healthy digestion and oral health. Users may experience benefits related to blood pressure regulation, enhanced relaxation, improved liver function, and better sleep quality. The iMatchme Soursop Graviola Liquid Drops are designed to be inclusive, being gluten-free, vegan-friendly, and made from natural ingredients, making them suitable for a wide range of dietary preferences and lifestyles. A key advantage of this product is its liquid extract form. Liquid supplements, such as these soursop drops, are generally preferred over capsules due to their superior absorption rate. They are processed more rapidly through the digestive system and absorbed into the bloodstream much faster than other supplement forms. Scientific studies indicate that the body can absorb a significantly higher percentage of minerals and vitamins when delivered in liquid form, ensuring that users receive the full benefit of the soursop graviola. The iMatchme Soursop Graviola Liquid Drops are incredibly easy to incorporate into a daily routine. The recommended dosage is 2ml daily, providing a convenient 30-day supply per bottle. Users are advised to shake the bottle well before each use. The drops can be taken directly under the tongue for quick absorption or easily added to water or any preferred drink, making them versatile for various lifestyles. Crafted with a natural flavor and designed for high absorption, these drops aim to deliver the highest possible benefits to individuals and their families, supporting a holistic approach to health and wellness. This product is a convenient and effective way to harness the traditional medicinal properties of soursop graviola.
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Study, Trial or Testing Result Summary
Members Only39 human studies · 13 improved
2 of these 39 human studies gave the ingredient by injection, not by mouth.
Vitamin C has the strongest evidence here, though the support is modest and mostly about colds. A pooled review of 29 placebo-controlled trials with 11,306 people taking at least 200 mg daily found colds were not less common in the general public. They were about half as common in marathon runners, skiers and soldiers, and colds were 8 percent shorter in adults and 14 percent shorter in children [1]. Another review found cold severity was 15 percent lower with at least 1 gram daily [2]. A pooled analysis found a 4 percent lower risk of respiratory infections and 9 percent shorter symptoms [3]. In 1,444 army recruits taking 6,000 mg daily, cold risk was 20 percent lower than placebo [4]. However, a review of eight reviews concluded vitamin C does not prevent catching colds [5], and a trial in marine recruits found colds no less common or shorter [6]. Graviola evidence is limited to two small look-back studies where it was combined with ellagic acid, which this product does not contain. Men with a papillomavirus infection had better semen quality and less lingering virus [7]. Women with a cervical papillomavirus infection had fewer abnormal smear results but did not clear the virus more often than vaccinated women [8]. Animal and cell studies are never counted.
See all 39 studies →Hide the studies
- Across 29 placebo-controlled trials with 11,306 people taking at least 0.2 g of vitamin C daily, colds were not less common in the general public but were about half as common in marathon runners, skiers and soldiers, and colds lasted 8% shorter in adults and 14% shorter in children.Vitamin C for preventing and treating the common cold.
- A review of eight systematic reviews covering 31 randomized trials concluded that taking vitamin C does not prevent people from catching a common cold.Does vitamin C prevent the common cold?
- In a pooled analysis of randomized trials in adults, vitamin C slightly lowered the risk of respiratory infections by 4% and shortened symptoms by 9%, with a stronger prevention effect in men and in middle-income countries.Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic revie…
- In 10 placebo-controlled trials of healthy people taking at least 1 g of vitamin C daily, cold severity was 15% lower than with placebo, with a clear benefit on severe symptoms but not on mild ones.Vitamin C reduces the severity of common colds: a meta-analysis.
- Five small, low-quality trials with 2,655 children and adults gave vitamin C at 125 mg to 2 g daily, and the evidence was too weak to tell whether it prevents or treats pneumonia.Vitamin C supplementation for prevention and treatment of pneumonia.
- A review of 39 randomized trials of eight supplements, including vitamin C, in healthy people under stress found some signs of benefit but too many gaps to draw firm conclusions about immune protection.Select Dietary Supplement Ingredients for Preserving and Protecting the Immune System in Healthy Individuals: A Systemat…
- A review of 13 studies in healthy adults found alternative vitamin C forms often raised white blood cell vitamin C and were better tolerated, with one study showing fewer colds, but more research is needed to confirm immune benefits.Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement …
- In 1,444 army recruits taking 6,000 mg of vitamin C daily for 30 days, the risk of getting a common cold was 0.80 times that of those taking placebo.Vitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits: randomised co…
- In 868 Navajo schoolchildren given vitamin C or placebo, there was no difference in how many got ill (133 vs 129), number of illness episodes, or illness length, though blood vitamin C levels were higher.Vitamin C and acute illness in Navajo schoolchildren.
- In a randomized trial of 688 adult women, 1 gram of vitamin C daily produced a small reduction in chest colds but no effect on simple colds.A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold.
- In 674 marine recruits given 2 grams of vitamin C or placebo daily for eight weeks, colds were no less common or shorter, though the vitamin C group rated their colds as less severe.Vitamin C prophylaxis in marine recruits.
- In 595 critically ill surgical patients, early antioxidant supplementation with vitamin C and vitamin E did not significantly reduce lung complications compared with standard care, but it reduced multiple organ failure and shortened time on the ventilator and in intensive care.Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients.
- In a 5-year double-blind trial of older Japanese adults, 500 mg of vitamin C daily cut the number of people with three or more colds, compared with 50 mg daily, but did not shorten or lessen the colds.Effect of vitamin C on common cold: randomized controlled trial.
- In 275 people with early COVID-19, a 10-day combination therapy including vitamin C was safe and well tolerated, but the study did not test whether it improved immune health.Read the study on PubMed (41693032) →
- In 311 National Institutes of Health employees taking 3 g of ascorbic acid daily for nine months (with extra doses at cold onset), the vitamin had at best a minor effect on the duration and severity of colds, and the results could be explained by a break in blinding.Ascorbic acid for the common cold. A prophylactic and therapeutic trial.
- In a double-blind study of 95 identical twin pairs over 100 days, vitamin C shortened cold episodes by about 19% but had no other significant effect compared with placebo.Vitamin C and the common cold: using identical twins as controls.
- In 120 stroke patients with swallowing difficulty, vitamin C stimulation added to routine swallowing training improved swallowing tests, nutrition markers and antibody levels compared with routine training alone.Effects of vitamin C stimulation on rehabilitation of dysphagia after stroke: a randomized trial.
- In 98 adults with mild to moderate coronavirus illness, 1000 mg of vitamin C daily for 14 days had no effect on symptom progression or quality of life compared with placebo.A Pilot of a Randomized Control Trial of Melatonin and Vitamin C for Mild-to-Moderate COVID-19.
- In 60 children prone to recurrent respiratory infections, a daily orange juice providing 70 mg of vitamin C was associated with a drop in infection episodes from about 6.75 to 2.62 per child.Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: preliminary data.
- In 28 people recovering from COVID-19, a single 1000 mg dose of vitamin C reduced one type of immune-related reactive oxygen species by 45% but did not raise nitric oxide levels.A Plant-Based Dietary Supplement Exhibits Significant Effects on Markers of Oxidative Stress, Inflammation, and Immune R…
- In 24 patients receiving stem cell transplants for myeloma or lymphoma, high-dose vitamin C (20 g daily for 10 days, then 500 mg twice daily until day 100) was linked to rising natural killer and CD3 immune cell counts from day 30 to day 100 and fewer infections, compared with standard care alone.Effect of vitamin C on immune reconstitution after bone marrow transplantation.
- In 20 children having surgery, ascorbate before premedication did not change neutrophil mobility during anaesthesia or surgery, and no infections occurred.Neutrophil mobility during anaesthesia in children. A trial of ascorbate premedication.
- In 12 adults who exercised for about two hours in heat, 1500 mg of vitamin C daily for 12 days lowered the stress hormone cortisol after exercise, but did not change salivary antibody levels or cold-like symptoms compared with placebo.Vitamin C supplementation and salivary immune function following exercise-heat stress.
- In healthy adults aged 55 and older, a 12-week multivitamin and mineral supplement raised blood vitamin C and zinc levels but did not change measured immune function compared with placebo.The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomiz…
- In older adults, a 30-day course of a multi-ingredient supplement that also contained vitamin C lowered inflammatory blood markers and improved lymphocyte levels, though they did not reach the levels seen in younger people; the vitamin C dose was not stated.Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study.
- In a randomized trial of ultramarathon runners and sedentary controls, taking 600 mg of vitamin C daily was linked to fewer upper airway infection symptoms in the two weeks after a race than placebo, with 33% of supplement takers developing symptoms versus 68% of placebo takers among runners.Vitamin C supplementation reduces the incidence of postrace symptoms of upper-respiratory-tract infection in ultramarath…
- In two trials of 8-9 year old children (172 and 642) given 1000 mg vitamin C daily, cold duration and severity seemed lower but cold incidence stayed the same or rose, and the total sick days were fewer only in the smaller pilot study.Vitamin C as a preventive medicine against common colds in children.
- In about 210 students (three groups of about 70) taking 1 gram daily for 15 weeks, the D-isoascorbic acid group had 34% fewer colds than the other two groups, which included the L-ascorbic acid group, so regular vitamin C showed no clear benefit.L-Ascorbic acid and D-isoascorbic acid in a common cold survey.
- In a large double-blind trial, 1 g of vitamin C daily gave a small, non-significant reduction in colds, but more people stayed illness-free and vitamin takers had about 30% fewer days of disability from illness than placebo takers.Vitamin C and the common cold: a double-blind trial.
- In older adults, 500 mg of vitamin C injected daily for one month improved T-lymphocyte response and skin test reaction compared with placebo, but did not change antibody levels.Effect of vitamin C supplements on cell-mediated immunity in old people.
- In a small feasibility study of people with a new common cold, 250 mg of vitamin C daily for 5 days was used only as the comparison arm against a warm humidified air treatment, and the abstract reports no benefit from vitamin C itself.Randomised controlled trial of rhinothermy for treatment of the common cold: a feasibility study.
- In a study of 433 women followed for a year, those with the highest dietary vitamin C intake were less likely to have a persistent human papillomavirus infection than those with the lowest intake.Dietary intake and risk of persistent human papillomavirus (HPV) infection: the Ludwig-McGill HPV Natural History Study.
- In a retrospective study of 50 men with a sexually transmitted papillomavirus infection, taking 100 mg of annona muricata plus 100 mg of ellagic acid daily for three months was associated with better semen quality and less viral persistence in semen than no treatment.The Use of Ellagic Acid and Annona Muricata Improves Semen Quality in Men with High-Risk Papillomavirus Infection.
- In a retrospective study of 40 women with persistent cervical papillomavirus infection, those taking an ellagic acid and annona muricata tablet for 12 months had fewer abnormal cervical smear results, but they did not clear the virus more often than women who received the vaccine, which cleared it more often.A retrospective study on two cohorts of immunocompetent women treated with nonavalent HPV vaccine vs. Ellagic acid compl…
- In hospital records of patients with upper respiratory tract infection, adding vitamin C injection to Xiyanping injection did not improve cure rates compared with Xiyanping alone.[Analysis of actual effects of combining xiyanping injection with vitamin C injection in treatment of upper respiratory …
- In 24 mice with a severe malaria-like infection, graviola leaf water extract combined with standard antimalarial treatment raised a immune-guiding chemical signal in the spleen compared with controls; this has not been tested in people.Annona muricata leaf water extract in combination with artemisinin-based combination therapy for increasing CCL19 levels…
- In a laboratory and mouse study, polysaccharides from graviola leaves boosted immune cells called dendritic cells and strengthened the T-cell response when used as a vaccine adjuvant, but this has not been tested in people.Annona muricata L.-Derived Polysaccharides as a Potential Adjuvant to a Dendritic Cell-Based Vaccine in a Thymoma-Bearin…
- In laboratory and mouse studies of a parasite infection, a graviola leaf extract reduced parasite levels and improved survival, but it also lowered some inflammatory signals, and this has not been tested in people.Anti-parasitic activity of Annona muricata L. leaf ethanolic extract and its fractions against Toxoplasma gondii in vitr…
- In rats given 100 to 400 mg/kg of a graviola leaf extract daily for 14 days, several parts of the immune response were suppressed, suggesting the extract weakens rather than supports immunity; this has not been tested in people.Immunosuppressive Effects of Annona muricata L. Leaf Extract on Cellular and Humoral Immune Responses in Male Wistar Rat…
Review Totals and Summary
Members Only2,757 reviews · 89% positive
The iMatchme Soursop Liquid Drops have garnered significant attention, with approximately 2757 ratings across various stores. Overall, customer feedback is largely positive, with 60% of star ratings being 4 or 5 stars, indicating a generally favorable reception for this liquid supplement. This summary focuses exclusively on the liquid drops, excluding reviews for other product forms like capsules or gummies. **What it Did for Buyers** Many customers report positive effects from taking the soursop drops. Some users found it beneficial for specific health concerns, such as managing blood sugar levels. One reviewer noted their "blood sugar running about 110 after one week" of use. Others experienced relief from respiratory issues, with one stating it "works great for phelm." General positive sentiment about its effectiveness is also present, with some simply saying "it works well." **What Buyers Complain About** Despite the positive feedback, some customers expressed dissatisfaction. A few users felt the product "didn't do the job for me" as described or expected. Concerns were raised about the product's formulation, with one reviewer stating it was "not the true sour sop formula." Another significant complaint centered on ingredients, specifically the inclusion of sucralose, which one customer found "very counter productive" due to its potential as a "digestive disruptor." Logistical issues, such as missing items in an order, were also mentioned. **Taste and Form** A recurring theme in positive reviews is the pleasant taste and ease of use of the liquid drops. Many customers describe the taste as enjoyable, with comments like "Very delicious" and "tastes good." The absence of bitterness is also highlighted, with one user noting "no bitter taste!" The liquid form is generally appreciated for being "easy to take," often consumed under the tongue. **Value for Money** The cost of the iMatchme Soursop Liquid Drops is a point of consideration for some buyers. While many find the product effective, a few reviewers mentioned that it can be "A bit costly to replace" for regular, ongoing use. One customer noted that "my limited budget can't handle on a regular basis," suggesting that the price point might be a barrier for some long-term users. **Who it Suits and Who it Did Not** This supplement appears to suit individuals looking for support with blood sugar management or phlegm relief, and those who appreciate a good-tasting, easy-to-take liquid supplement. Repeat purchases, with customers stating "will order again," suggest satisfaction among a loyal user base. However, it may not be suitable for those who are sensitive to sucralose, are seeking a "true" soursop formula without additives, or those on a strict budget for regular supplementation. It also did not suit individuals who found it ineffective for their specific needs.
Biohacker Summary
Members Only0 of 10 recommend it
Vitamin C is the main ingredient in this product, and all ten panelists spoke about it, with most recommending or using it. They take it for immune support, for skin and collagen, and as an antioxidant, and several also mention it for detox, sleep, and recycling the body's own antioxidants. Many pair it with collagen, and some get it from a multivitamin or a fizzy drink; one liked a liquid liposomal form, and another favors a blend of several forms with citrus bioflavonoids. Doses named include about 250 milligrams a day, 125 to 200 milligrams a day for sleep, a gram a day in divided doses, and an extra gram a day. Cautions came from one panelist who says high doses may blunt the benefits of exercise and who questions whether ascorbic acid is true vitamin C, and one who stopped a topical serum because of its smell and said supplements beyond normal levels did not protect against cataracts.
See all 10 biohackers →Hide the biohackers
Ben Greenfield · Vitamin C · recommends
- States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
- Mentions vitamin C as part of a bare-minimum protocol.
- Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
- Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
- Recommends Vitamin C for skin repair post-tattoo.
- Does not agree that ascorbic acid is vitamin C, comparing it to calling chaff wheat, and notes that it is made from genetically modified cornstarch or corn syrup byproducts using solvents.
- Warns against ascorbic acid, stating that it does not cure scurvy and that the world has been led astray by the deception around it versus the whole food vitamin C complex.
- Warns against taking 1,000 mg of vitamin C immediately after a workout for individuals under 50, as it can dull the body's natural adaptation signal.
- Warns that using high-dose antioxidants like vitamin C directly before or after a hyperbaric session is not a great idea, as it could impair some of the effects by reducing reactive oxygen species.
- Warns that taking a whole bunch of antioxidants like vitamin C after a workout can suppress the body's inflammatory response, which is necessary for benefits like mitochondrial proliferation and satellite cell generation for new muscle.
- Mentions soursop or graviola as being popular for its anti-cancer benefits.
Siim Land · Vitamin C · recommends
- Recommends taking vitamin C with collagen to support joint collagen synthesis.
- States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
- Lists sauerkraut and fruit as sources of Vitamin C.
- Notes that Vitamin C is one of several supplements with human evidence.
- Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
- States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
- States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
- Mentions vitamin C in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
- Was found to be vitamin C deficient by True Health and Mayo Clinic tests, and now addresses this by eating one extra kiwi fruit daily.
- States that the biggest evidence for multivitamin is that it improves cognition and enhances episodic memory in elderly people, who tend to have worse diets and are more likely to be deficient.
Dr. Eric Berg · Vitamin C · neutral
- Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
- Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
- Recommends Vitamin C as a cofactor, especially for collagen.
- States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
- Highly recommends taking natural food vitamin C, about 500 mg, at the first sign of a cold.
- Recommends consuming foods high in vitamin C to block the effects of grains.
- Recommends ensuring that collagen supplements come with vitamin C.
- Vitamin C works as an antioxidant that supports skin and artery health.
- Recommends pairing collagen with vitamin C to support absorption.
- Sauerkraut also contains vitamin C and beneficial bacteria that may support digestive health.
Thomas DeLauer · Vitamin C · recommends
- Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
- Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
- Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
- Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
- Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
- States that collagen synthesis is vitamin C dependent, in the context of glowing skin.
- Recommends Vitamin C for sleep, noting that intake in the range of 125 to 200 mg per day is associated with a lower risk of sleep disorders and sleep apnea, with the benefit plateauing beyond this range.
- Recommends consuming a little bit of vitamin C, such as a couple of berries or kiwi, along with flavanol-rich cocoa to help the delicate flavanols hold up and prevent oxidation in the gut.
- Explains that vitamin C improves the ability of neutrophils to engulf bacterial infections, and that they have a greater ability to engulf larger infections.
- Recommends using a multivitamin to ensure adequate micronutrient intake, especially when wholesome food is less available.
Dave Asprey · Vitamin C · recommends
- Recommends taking vitamin C for better skin health.
- States that currently, he is only taking vitamin C and vitamin D.
- Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
- Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
- Dave Asprey recommends taking maybe a gram of vitamin C a day in divided doses, noting that plasma levels peak around 250 milligrams twice a day.
- Recommends Qualia Vitamin C Plus, highlighting its combination of seven forms of vitamin C with 250 mg of citrus bioflavonoids, which helps with absorption and use for building collagen and a strong immune system.
- Warns that taking too much vitamin C can raise oxalate levels, emphasizing that everything has risk and reward.
- Recommends Vitamin C as the real biological fix for deep focus issues, explaining how the brain hoards it at levels 100 times higher than blood and how to bypass the blood-brain barrier.
- States that Ensure is like SlimFast but worse, and that its ingredients, including synthetic vitamins, guar gum, maltodextrin, high fructose corn syrup, and seed oils, are disgusting and should not be given to sick or well people.
- Recommends IV Vitamin C, or even oral versions, for helping the body heal and for cells to remain supple and fluid.
Dr. Mark Hyman · Vitamin C · recommends
- Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
- Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
- Mentions topical vitamin C as an antioxidant that can help skin with aging.
- Mentions that what they do when a cold comes on is not just vitamin C.
- Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
- Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
- Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
- Used intravenous vitamin C cocktails to help him detoxify and recover from chronic fatigue.
- Recommends vitamin C for immune system support and modulation.
- Relies on Big Bold Health's HTB Immune Energy Chews, which deliver 1000mg of sprouted Himalayan tardy buckwheat, along with vitamin C, D, magnesium, and zinc, to support immune balance, resilience, energy, and focus.
Dr. Rhonda Patrick · Vitamin C · neutral
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
- Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
- Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
- Notes that ~35% of Americans are low in vitamin C.
- Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
- Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
- Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory.
- Currently takes the Pure Encapsulations O.N.E Multivitamin.
- Rhonda's current supplement routine includes Vitamin C.
Andrew Huberman · Vitamin C · uses
- Takes a multivitamin every day for longevity.
- Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
- Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
- Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
- Started taking AG1 in 2012 and still takes it every single day to ensure he meets his quota for daily vitamins and minerals and to support gut health, which is critical for proper brain function, immune system, and neurotransmitter production.
- Has been taking AG1 daily since 2012 because it is the highest quality and most complete foundational nutritional supplement, ensuring he gets all necessary vitamins, minerals, and micronutrients for daily health.
- Has been drinking AG1 since 2012, finding it difficult to get enough vitamins, minerals, micronutrients, and adaptogens from diet alone. He finds that taking AG1 daily improves all aspects of his health, including physical and mental health, performance, recovery from exercise, and immune system strength, and also notices more mental clarity and energy.
- Recommends AG1 as the highest quality and most complete foundational nutritional supplement, containing vitamins, minerals, probiotics, prebiotics, and adaptogens to cover dietary gaps and support a demanding life.
- States that AG1 is the highest quality and most complete foundational nutritional supplement available, containing vitamins, minerals, probiotics, prebiotics, and adaptogens, and that he has been taking it daily since 2012, often twice a day, to bolster his energy, immune system, and gut microbiome.
- Huberman mentions that vitamin C seems to help with the absorption or utilization of collagen protein.
Peter Attia · Vitamin C · stopped
- Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
- Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
- States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
- Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
- Notes that while vitamin C deficiency is associated with an elevated risk of cataract, supplementation to supranormal levels has been conclusively shown not to protect against cataract formation.
- Mentions that a survey of doctors showed they recommend Vitamin C for COVID-19, but notes there is no real evidence behind it.
- Expresses skepticism about 'panacea treatments' for cancer, specifically mentioning a 'twenty thousand dollars of vitamin C' treatment, implying it's an example of something he's 'squirrely' about due to cost and unproven claims.
- Asks if vitamin C matters for immune function, suggesting a need for a definitive study.
- Warns against the "total nonsense" of taking excessive amounts of vitamin C, especially in specific forms like liposomal vitamin C, for immunity, stating that it is idiotic and potentially dangerous to think it will offer immunity.
- Would love to see more research done on mega dose intravenous vitamin C for viral infections, noting some interesting but not followed-through research from the 1960s.
Bryan Johnson · Vitamin C · neutral
- Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
- Applies vitamin C after showering.
- Takes 250 milligrams of Vitamin C.
- Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
- Bryan Johnson takes Vitamin C daily as part of his Longevity Mix, which is an antioxidant-rich essential vitamin that supports immune function and metabolic energy.
- He uses Vitamin C, typically in a serum, in the morning for skin health.
RAL Summary
Members OnlyTier 2 for Immune Health
The tier rests on vitamin C, where pooled reviews, including the largest with 11,306 people, show shorter colds and fewer colds in people under heavy physical stress [1]. All 216 counted reviews are positive.
Take 2 servings a day to match the dose that worked in the studies.
Where the evidence disagrees: 14 of the 39 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Immune system, Respiratory system
Combine with: To enhance the cellular and DNA protective benefits of Soursop, consider combining it with other potent antioxidants like Resveratrol, Astaxanthin, or CoQ10 to further combat oxidative stress. For direct support of cellular repair mechanisms and energy production, NAD+ precursors such as NMN or NR, alongside PQQ and Alpha-Lipoic Acid, can be highly synergistic. Additionally, Omega-3 fatty acids can provide anti-inflammatory support crucial for overall cellular health and longevity.
Possible side effects: No major side effects reported.
Supplement Facts
Graviola 300 mg · Graviola 1500 mg · Vitamin C 80 mg
| Graviola (Soursop) (Annona muricata) (fruit) | 300 mg | † |
| Graviola (Soursop) (Annona muricata) (leaf) | 1,500 mg | † |
| Vitamin C | 80 mg | 89% |
Other ingredients: Other ingredients: Distilled Purified Water, Vegetable Glycerin.
Label source: Imatchme · Report a label change
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- What Supplements and Vitamins Should Not Be Taken TogetherArticle · Sep 7, 2026
- When Is the Best Time to Take Vitamins and Supplements?Article · Jun 15, 2026
Graded October 29, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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