Innovative Diet Labs (IDL) Stimamine Black Review
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Study, Trial or Testing Result Summary
Members OnlyHuman studies
No human studies have tested ephedra, the one named ingredient here at 50 milligrams a day, for reversing aging or repairing cells and DNA. All the evidence comes from small animal studies, and it points in opposite directions. In rats and mice harmed by a tumour, a pesticide or chemotherapy, ephedra plant extracts lowered oxidative stress, inflammation, cell death or DNA damage in the liver, kidneys or testes [1][2][3]. But ephedrine, the main active compound in ephedra, did the opposite in rats. One week of it raised oxidative stress, inflammation and cell death in the liver and impaired liver function [4]. It also damaged the retina [5]. A longer course damaged the heart [6]. The newest of these studies found harm. The animal doses were given by body weight, so it is unclear how they compare with the dose in this product. Most of the formula, 515 milligrams, is a proprietary blend called Stim Matrix 5. Its contents and doses are not disclosed, and no studies were found for it. Taken together, these studies do not show that this product helps people slow or reverse aging. Animal and cell studies are never counted.
Review Totals and Summary
Members OnlyWhat buyers say
Extensive customer reviews and qualitative feedback are currently being aggregated for this product. Check back soon for a detailed sentiment analysis.
Biohacker Summary
Members Only0 of 10 recommend it
Six of the ten panelists spoke about ephedra, the main ingredient, and none of them recommend it. Three warn against it, citing raised blood pressure, a racing heart, adrenaline stress that could lead to adrenal fatigue and weight regain, and many side effects, with one saying it should not go to anyone with high blood pressure or who is pregnant. Two said they stopped: one used it for weight loss alongside starving himself and now calls that a terrible approach, and the other found the pills too stimulating. The last two were neutral, simply describing it as a powerful plant with a long history, and nobody gave a dose, a preferred form, or anything to pair it with.
See all 6 biohackers →Hide the biohackers
Dr. Eric Berg · Ephedra · warns
- Notes that ephedra, also known as ma huang, was taken off the market because it increases adrenaline but comes with many side effects.
- Warns against using ephedra as a quick fix for weight loss because it stimulates adrenaline, which can lead to adrenal fatigue and subsequent weight gain.
- Discusses Ephedra, noting it was taken off the market and that it tends to increase blood pressure, so it should not be given to someone with high blood pressure or who is pregnant.
Thomas DeLauer · Ephedra · stopped
- Used to take Ephedra to lose weight, along with starving himself, which he now considers a terrible approach.
- Warns against Ephedra, stating that while it was effective for fat loss, it made up less than 1% of total supplement sales but 64% of all adverse effects, and animal studies showed serious neurotoxicity and changes to neurons and behavior.
Peter Attia · Ephedra · neutral
- States that ephedra is a natural plant product discovered in the 1800s to have bronchodilating properties, leading to the development of synthetic amphetamines when demand outstripped supply.
Ben Greenfield · Ephedra · warns
- Warns against using ephedra and high amounts of caffeine, advising not to destroy one's metabolism but to gently speed it up.
- Warns against using Ephedra pills, stating they can really get one's heart rate raising and do nasty things to blood pressure.
Andrew Huberman · Ephedra · stopped
- Andrew Huberman mentions that ephedra and ephedrine pills were sold over the counter when he was younger, but they always felt too stimulatory for him.
Dave Asprey · Ephedra · neutral
- Mentions Ephedra as the key ingredient in herbal ecstasy and describes it as one of the most powerful plants known to man.
RAL Summary
Members OnlyTier 4 for Healthy Aging
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system, Liver, Kidneys, Eyes, Nervous system
Combine with: Combine with a healthy diet and lifestyle.
Possible side effects: In rat studies, ephedrine caused liver, retina and heart damage, with higher oxidative stress, inflammation and cell death. No reviews were available to report side effects in people.
Supplement Facts
Total Blend 565 mg · Ephedra 50 mg · Stim Matrix 5 515 mg
| Total Blend | 565 mg | † |
| Ephedra | 50 mg | † |
| Stim Matrix 5 | 515 mg | † |
Other ingredients: Gelatin, FD&C Blue #1, FD&C Red #40, FD&C Yellow #5, Magnesium Stearate.
Directions: Never exceed the recommended maximum dosage. Do not consume synephrine, caffeine or thyroid-boosting compounds from other sources, including but not limited to, coffee, tea, soda and other dietary supplements or medications containing phenylephrine or caffeine or any stimulants whatsoever. Do not use this product for longer than 2 months. Suggested Use: As a dietary supplement consume capsule 30 minutes before eating a meal. Do not consume late evening or night time if you are sensitive to simulants as you may experience difficulty sleeping. Never take more than 1 capsule at once and never exceed 2 capsules per 24 hour period.
Barcode (UPC) 021325852518 · Label source: NIH label database · Report a label change
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Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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