Jacked Factory Essential Series Yohimbine Review

Discontinued item listing for Essential Series Yohimbine, 270 veggie capsules, 125 mg per capsule, from Jacked Factory. The scraped page text contains no product description.

Product Focus: Weight and Metabolism for MenAlso covers:BrainHeart
Tier ⓘ
Tier 4 · Rank 5
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 5 within Tier 4 for Weight and Metabolism for Men; 13 of 25 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
47 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
89% of 77
Biohacker Mentions
4 of 10

Study, Trial or Testing Result Summary

Members Only12 human studies · 5 improved
12 human studies5 improved5 no effect184 people studied

This product holds 125 milligrams of yohimbe bark extract per capsule, which the store listing says gives about 2.5 milligrams of yohimbine. At two capsules a day that is far below the 18 to 43 milligrams a day used in the trials below. Even at those higher doses, the results for weight are mixed. In 20 professional male soccer players, 20 milligrams a day of yohimbine for three weeks lowered body fat percentage compared with placebo, but body weight and muscle mass did not change [1]. A longer six month trial in 47 men, using up to 43 milligrams a day, found no effect on body weight, body fat or fat distribution [2]. In obese women on a 1,000 calorie diet, one three week trial at 20 milligrams a day found slightly more weight loss than placebo [3], while an eight week trial at 18 milligrams a day found no change in weight or blood fats [4]. A review of weight loss supplement trials, including yohimbe, found no convincing evidence that any of them work [5]. Animal and cell studies are never counted.

See all 12 studies →Hide the studies
  • Systematic review · 2004 · Yohimbe No effect
    A review of randomized trials of weight-loss supplements, including yohimbe, found no convincing evidence that any specific supplement works for reducing body weight, and none could be recommended.
    Dietary supplements for body-weight reduction: a systematic review. · The American journal of clinical nutrition
  • Randomized trial · 1991 · 47 people · 26 weeks · Yohimbe No effect
    In 47 men given high-dose yohimbine (up to 43 mg a day) or placebo for six months, yohimbine had no effect on body weight, body fat, or fat distribution.
    Yohimbine does not affect fat distribution in men. · International journal of obesity
  • Randomized trial · 2006 · 20 people · 3 weeks · Yohimbe Improved
    In 20 professional male soccer players, 20 mg a day of yohimbine for 21 days lowered body fat percentage compared with placebo, though body mass, muscle mass and exercise performance did not change.
    Yohimbine: the effects on body composition and exercise performance in soccer players. · Research in sports medicine (Print)
  • Randomized trial · 1991 · 20 people · 3 weeks · Yohimbe Improved
    In 20 obese women on a 1,000-calorie diet, 20 mg a day of yohimbine for three weeks led to more weight loss than placebo (3.55 kg vs 2.21 kg).
    Does yohimbine act as a slimming drug? · Israel journal of medical sciences
  • Randomized trial · 1986 · 19 people · 8 weeks · Yohimbe No effect
    In 19 obese volunteers on a 1,000-calorie diet, 18 mg a day of yohimbine for eight weeks did not change body weight or blood fat measures compared with placebo.
    [Lack of efficacy of yohimbine in the treatment of obesity]. · Journal de pharmacologie
  • Randomized trial · 2019 · 7 people · 4 weeks · Yohimbe Improved
    In 7 sedentary women using a diet and walking program for 28 days, a topical lotion containing yohimbe reduced thigh circumference, skinfold thickness and thigh fat mass more than placebo on the other thigh.
    Effects of a topical lotion containing aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola on thigh circumferen… · Journal of cosmetic dermatology
  • Controlled trial · 1987 · 28 people · 4 weeks · Yohimbe Improved
    In 28 obese women on a reduced-calorie diet, creams containing yohimbine (alone or combined with other agents) applied to one thigh for four weeks reduced thigh girth more than placebo on the other thigh; this study was in women, not men.
    Regional fat loss from the thigh in obese women after adrenergic modulation. · Clinical therapeutics
  • Controlled trial · 1995 · 18 people · 4 weeks · Yohimbe No effect
    In 18 overweight women, a yohimbine ointment applied to one thigh for 4 weeks did not produce significant thigh girth loss compared with placebo, while other topical agents in the same series did.
    Topical fat reduction. · Obesity research
  • Controlled trial · 2015 · 12 people · Yohimbe Mixed
    In 12 healthy active adults, a single dose of a multi-ingredient product containing yohimbine raised fat burning before exercise and lowered perceived exertion during exercise, but fat burning did not differ from placebo during exercise and hunger and mood did not differ.
    Acute effectiveness of a "fat-loss" product on substrate utilization, perception of hunger, mood state and rate of perce… · Journal of the International Society of Sports Nutrition
  • Study · 2001 · 13 people · Yohimbe No effect
    In 13 obese women on a very low-calorie diet, 10 days of ephedrine and caffeine with or without yohimbine did not change blood levels of a hunger-related hormone or heart responses to exercise; weight loss outcomes were not reported.
    Neuropeptide Y in obese women during treatment with adrenergic modulation drugs. · Medical science monitor : international medical journal of experimental and clinical research
  • Study · 1991 · Yohimbe Mixed
    A single oral dose of yohimbine raised fat release into the blood in fasting women, lean and obese alike, over four hours, but body weight was not measured and the study did not involve men.
    Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women. · International journal of obesity
  • Study · 1986 · Yohimbe Improved
    In a small study of obese and lean women, blocking one type of adrenaline receptor with yohimbine increased fat breakdown and exercise energy use, and yohimbine given during a slimming program increased weight loss without side effects.
    Adrenergic control of lipolysis and metabolic responses in obesity. · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Review Totals and Summary

Members Only77 reviews · 89% positive
77 reviews · IHerb 77
89% positive5% neutral6% negative

Buyers of the Jacked Factory Essential Series Yohimbine capsules are mostly positive, praising the energy boost and the price, though it is strong enough to disrupt sleep if taken late. It carries about 77 ratings across the stores. Reviews of other products (a John Wick pre-workout, NITROSURGE and Burn-XT) appeared on the page and were left out, as they are not about this product. **What buyers say it did for them:** Most report a noticeable energy lift, often within the first days. One said, "I have an energy boost for the whole day." Another takes it with L-carnitine before training and says it gives "a noticeable boost in energy and helps with fat burning." Others describe it as stimulating the metabolism and raising the heart rate, and say it works best with fasted cardio or a cutting phase. One buyer said it "works better on women than men," and another said it didn't make their blood pressure jump or overload the heart. **What they complain about:** The complaints are few, and mostly about strength and timing. One buyer who took it in the afternoon "didn't get to sleep until 1:30 a.m." even with sleep supplements, and advises taking it only in the morning. Another had chills, a cold feeling and a slight runny nose for the first few days before it passed after three or four days. One reviewer who tried it noted no stomach problems, and another had no jitters when taking it on an empty stomach with enough water. **Taste, smell, pill size and form:** The capsules get good marks. One buyer said they "were easy to swallow" and "don't get caught in your throat." Another mentioned no aftertaste in the mouth. Nobody complained about smell or taste. **Value for money:** Buyers see it as good value. One called it "Very cheap for two month supply." Another, who had expected to double the dose because the milligrams per capsule were lower than their previous product, still felt the many capsules in the bottle made up for it and called it "Great Value." Others call the price good and the bottle size sufficient. One reviewer noted that delivery was fast and the item arrived undamaged and matched the photo. **Who it seems to suit and who it did not:** It seems to suit people who want a fat-loss or training aid and can take it in the morning or on an empty stomach, such as fasted cardio or pre-workout users. One buyer took it alongside caffeine and suggested starting at a lower dose to check tolerance. A different buyer found the low dose useful for jet lag, flying or shift work sleep problems, which is the opposite of the sleeplessness the afternoon user had, so reactions seem to vary. Those sensitive to stimulants, or who take it late in the day, may find it too strong. A few reviewers left only short remarks such as "works" or "good quality," so there is little more to go on beyond those points.

Biohacker Summary

Members Only4 of 10 recommend it
4 of 10 biohackers on our panel recommend it

The panel does not back yohimbe, the main ingredient here, as a group: only five of the ten spoke about it, and the views are mostly cautious. Two of them warn against it, saying it mimics adrenaline, can overstimulate, and brings side effects even though it may help with weight loss and libido. One tried it once before skating, felt more fear and a faster heart rate, and never took it again. One is a big fan of low doses and has used a cream on his abdomen for stubborn fat, and he earlier said pure yohimbe HCL is better than extract, which gives only a negligible amount. The fifth has used it for erection quality and suggested it for breathwork, and once suggested 0.1 mg per pound of body weight, but after eyeballing a dose of the HCL form he had extreme anxiety, heart palpitations, sweating and beet-red skin, and warned others off it.

See all 5 biohackers →Hide the biohackers
  • Dr. Eric Berg · Yohimbe · warns
    • 4 Oct 2026 · warns · YouTube ↗
      Does not recommend yohimbe or yohimbine, extracted from tree bark, because it tends to increase adrenaline and help with weight loss and libido, but has side effects.
  • Thomas DeLauer · Yohimbe · uses
    • 9 Apr 2025 · uses · YouTube ↗
      Is a huge fan of low-dose yohimbe personally, noting its science and how it blocks alpha adrenergic receptors, and he used yohimbe cream on his abdomen for stubborn fat.
    • 9 Jul 2021 · recommends · YouTube ↗
      Recommends yohimbe HCL for those wanting pure yohimbe, noting that yohimbe extract provides only a negligible amount.
  • Siim Land · Yohimbe · warns
    • 15 Feb 2025 · warns · YouTube ↗
      Warns that Yohimbe mimics adrenaline, which can lead to overstimulation.
  • Dave Asprey · Yohimbe · stopped
    • 6 Aug 2024 · stopped · YouTube ↗
      Took Yohimbe one time before skating and felt it amplified his fear and heart rate, so he never took it again.
  • Ben Greenfield · Yohimbe · neutral
    • 10 Dec 2022 · neutral · YouTube ↗
      Suggests yohimbe as a vasodilatory substance that could be thrown into the mix for breathwork.
    • 3 Nov 2022 · uses · YouTube ↗
      Mentions Yohimbe as an ingredient in Joymode, which he uses for erection quality and firmness.
    • 10 Dec 2019 · warns · YouTube ↗
      Warns against Yohimbe HCL, describing a past experience where he eyeballed a dose of the pharmaceutical extract and experienced extreme anxiety, heart palpitations, sweating, and beet-red skin, calling it the closest he's been to needing hospitalization.
    • 7 Dec 2019 · warns · YouTube ↗
      Warns against Yohimbe HCL, describing it as a pharmaceutical extract that caused his heart to explode, beet-red skin, sweating, and the worst anxiety he'd ever had, almost sending him to the hospital.
    • 10 Aug 2017 · recommends · YouTube ↗
      Recommends Yohimbe as a reliable treatment for erectile dysfunction, but warns that it can elevate heart rate and cause anxiety, suggesting a dose of 0.1 mg per pound of body weight.
    • 27 Jun 2012 · neutral · Podcast ↗
      Ben discusses Yohimbe HCL for fat loss, noting contradicting information about its efficacy if there is any insulin response.
    • Date not recorded · uses · Website ↗
      Uses Yohimbe as an ingredient in Joy Mode, which he takes before sex to support erection quality and firmness, blood flow, and sex drive.
    • Date not recorded · warns · Website ↗
      Advises staying away from Yohimbe if concerned about cortisol.
    • Date not recorded · warns · Website ↗
      Mentions yohimbe could reduce visceral fat stores more quickly by blocking alpha receptors in fat cells, but warns against it due to its potent central nervous system stimulant effects, which make him feel like he's going to have a heart attack.

RAL Summary

Members OnlyTier 4 for Weight and Metabolism for Men

The dose was marked full by comparing 250 milligrams of bark extract with 20 milligrams of pure yohimbine, but the listing gives about 2.5 milligrams of yohimbine per capsule, roughly 5 milligrams a day, well below the 18 to 43 milligrams studied, and those trials disagree anyway, so study support does not carry this grade. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 5 of the 12 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Metabolic system, Nervous system, Cardiovascular system

Combine with: For fat-loss use, yohimbine is commonly stacked with caffeine and green tea extract (EGCG) for added thermogenesis, though caution is needed because stimulant stacking can amplify jitters, anxiety, and elevated heart rate and blood pressure. L-carnitine or CLA may support fat metabolism, and taking it fasted before low-intensity cardio is the typical protocol. If the actual goal is libido, better-supported options include ashwagandha (stress and testosterone support), tongkat ali, fenugreek, maca, zinc, and vitamin D, with L-citrulline or L-arginine for blood flow. Men with hypertension, anxiety disorders, or on meds or meds should consult a doctor before using yohimbine.

Possible side effects: The studies given report no side effects. Buyer reports mention trouble sleeping when taken later in the day, a faster heart rate, and chills with a runny nose in the first few days.

Supplement Facts

Yohimbe Bark Extract 125 mg
Supplement Facts
Serving Size 1 Capsule(s)
Servings Per Container 270
Amount Per Serving% Daily Value
Yohimbe Bark Extract125 mg†
† Daily Value not established.

Other ingredients: Hypromellose capsule, L-Leucine.

Directions: Yohimbine may also be stacked with other Jacked Factory fat burners - like Lean XT, Burn XT, or Diet XT - for enhanced weight loss support. Directions: As a dietary supplement consume 1 capsule, 1-2 times daily, 20 minutes before meals or as directed by a physician. Stack with Burn XT or Diet XT for maximum weight loss results.

Barcode (UPC) 628250670592 · Label source: NIH label database · Report a label change

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Graded November 10, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.