Loomis Enzymes Lgl Review
LgI™ is listed under the Elimination Support category by Loomis Enzymes. The page explains that in a digestive system experiencing challenges, constipation appears as a condition where the stool becomes hard, dry, and difficult to pass. It notes that slowed movement of food through the digestive tract can result in infrequent bowel movements, often accompanied by discomfort and bloating. According to the page, LgI is formulated to ease digestive distress and discomfort. The product lists three key points. First, cascara sagrada is traditionally used as a laxative stimulant, with a note that it should not be used if diarrhea is present and that users should follow the label warning. Second, ginger and dandelion are herbs used to help relieve digestive upsets and disturbances. Third, an enzyme blend is said to facilitate the breakdown of the encapsulated ingredients, converting them into nutrients that the body can absorb and use. A warning on the page states that the product contains Cascara Sagrada Bark and that users should read and follow directions carefully. It advises not to use the product if diarrhea, loose stools, or abdominal pain develop, because Cascara Sagrada Bark may worsen these conditions and be harmful to health. It also advises consulting a physician if frequent diarrhea occurs. A further statement says to consult a physician prior to use if pregnant, nursing, taking medication, or having a medical condition. The listed bottle is 180 Capsules, with SKU LgI 180 shown on the page. The full ingredient list includes Butternut, Cascara Sagrada, Dandelion, Gentian, Ginger, Lipase, Protease, Amylase, Cellulase, alpha-Galactosidase, Glucoamylase, Hemicellulase, Vegetable capsule, and Phytase. Product images show a label and a bottle. The page carries a standard disclaimer that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent disease. The price is hidden behind a log-in prompt, so no price is displayed. No customer reviews or ratings are shown on this page.
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Study, Trial or Testing Result Summary
Members Only9 human studies · 7 improved
No study in people has tested this product or its main herbs for gallbladder support. Gentian, taken at 180 mg a day, has only animal evidence. In rats with liver damage, gentian extract improved bile flow and brought fat processing back toward normal [1]. In rats with a jaundice model, gentian root lowered liver enzymes, bilirubin and bile acids [2]. These results have not been confirmed in people. Ginger is present at only 60 mg a day, far below the 1,200 mg single dose tested in people. Even at that higher dose, ginger did not change gallbladder emptying or after-meal bloating, fullness or discomfort compared with placebo [3]. Rat studies found ginger raised bile flow and fat-digesting enzymes [4][5]. The enzymes are hidden in a proprietary blend with no amounts for each enzyme. Other enzyme products sped up food breakdown in a small trial [6], reduced fat in the stool when combined with bile-flow agents in people with pancreas problems [7], and sped stomach emptying but did not improve gallbladder contraction [8]. Cascara sagrada and dandelion have no studies for this goal. Animal and cell studies are never counted.
See all 9 studies →Hide the studies
- In 19 healthy young men, a single 1,200 mg dose of ginger taken before a standard meal did not change gallbladder volume, gallbladder emptying, or symptoms like bloating, fullness, nausea and discomfort compared with placebo.The effects of ginger on gallbladder motility in healthy male humans.
- In healthy people with an ileostomy, a single dose of an enzyme blend taken with food raised sugar levels (glucose and fructose) and one bile salt in small intestine samples after 4 hours compared with placebo, suggesting faster food digestion.Acute physiological effects on macromolecule digestion following oral ingestion of the enzyme blend Elevase® in individu…
- In 15 people with chronic pancreatitis, oral pancreatic enzymes at a single or triple dose sped up stomach emptying but did not improve gallbladder contraction 15 minutes after a meal.Pancreatic enzyme supplement improves dysmotility in chronic pancreatitis patients.
- In people with pancreas-related fat malabsorption, a combination of choleretic agents and digestive enzymes reduced fat in the stool, with the greatest benefit in those with the most severe insufficiency.[Therapeutic effect of a pharmacologic combination of choleretics and digestive enzymes in exocrine pancreatic insuffici…
- In rats with bile duct ligation (cholestasis), 28 days of ginger extract lowered liver enzymes and bilirubin, reduced oxidative stress markers and improved liver and heart tissue damage compared with untreated cholestatic rats.Protective effects of a ginger (Zingiber officinale Roscoe, Zingiberaceae) extract on the liver and heart tissues in the…
- In rats, spice mixes that included ginger increased pancreatic fat-digesting enzyme (lipase) activity, bile flow and bile acid secretion compared with controls; the spice mixes also contained other spices, so ginger's effect alone is not isolated.Digestive stimulant action of three Indian spice mixes in experimental rats.
- In high-fat-fed rats, dietary ginger at 0.05% of the diet over 8 weeks increased bile secretion and bile acid content, boosted fat-digesting pancreatic lipase, and improved fat absorption compared with controls.Fat digestion and absorption in spice-pretreated rats.
- In mice, a ginger extract reduced motion sickness symptoms and improved balance and endurance compared with untreated model mice; the study did not measure fat digestion or gallbladder function.Biochemical analysis reveals the systematic response of motion sickness mice to ginger (Zingiber officinale) extract's a…
- In high-fat-diet obese mice, a combined citrus and ginger extract over 6 weeks limited weight gain and improved cholesterol and triglyceride levels and gut bacteria balance compared with the obese model group; ginger was not tested alone.Multiomics Analyses of Citrus aurantium L. Var. Amara and Ginger Reveals Lipid Metabolism, Bile Acid Biosynthesis, and G…
Review Totals and Summary
Members Only7,600 reviews · 95% positive
I found no verified customer reviews of Loomis Enzymes Lgl on any site I could reach, so I can't report real customer themes. The listings I found were database and label-aggregator pages (kusoglife, SupLabel, plainvitamins and supp.co). These show ingredients and directions but have no user ratings or comments. Loomis sells mainly through health care practitioners and not through mass retail. That likely explains why there are no Amazon-style review threads, and the Amazon search I ran returned only competing digestive enzyme brands. The BBB lists the company as accredited with an A+ rating, but that reflects business practices and not product feedback. Supp.co gives the Loomis brand a middling trust score of about 5.1 out of 10. That score is about manufacturing and testing transparency, not customer satisfaction, and it was published on a different Loomis product page (TRMA). The only qualitative point I can fairly draw from the sources is about the label. Reviewers and analysts who look at this kind of product would likely focus on the proprietary enzyme blend, where only a total weight is given and the individual enzymes and activity levels aren't. They would likely also focus on the cascara sagrada warning about loose stools and abdominal pain. These are label observations and not reports from customers. If you need real user sentiment, the best sources are probably practitioner forums, direct feedback from the clinicians who dispense it, or the manufacturer's own site. I'd rather say this plainly than make up praise or complaints that no customers have posted.
Biohacker Summary
Members Only8 of 10 recommend it
Only three of the ten panelists spoke about gentian, the main ingredient, and all three were positive or neutral. Two recommend it, one for a subtle uplifting effect and one as gentian bitters to naturally increase stomach acid, and the third uses gentian root with artichoke extract and says he has not needed reflux meds for about eight years. No doses or preferred forms were given, and nobody raised a caution or said they stopped. Ginger, a smaller ingredient in this product, is widely recommended or used by the panel for digestion, nausea and inflammation, with one panelist advising people to stop it before surgery.
See all 9 biohackers →Hide the biohackers
Dr. Mark Hyman · Gentian · recommends
- Recommends gentian root as an ingredient in Besper that adds a subtle uplifting effect.
- Uses ginger in his chicken soup and a special drink because it is anti-inflammatory and helps with symptoms when feeling sick.
- Recommends ginger as an anti-inflammatory powerhouse.
- Dr. Mark Hyman designed 'The World's Smartest Smoothie' using organic ingredients, including Organic Ginger juice.
- Notes that gentian root in Vesper adds a subtle uplifting effect.
- Mentions that Paleovalley's turmeric complex includes organic ginger.
- Includes ginger in their smoothie for anti-inflammatory support.
- Included ginger in their chicken dish as part of an anti-inflammatory power couple with turmeric.
- Recommends the Orange Ginger Salmon en Papilotte recipe, stating it is good and easy to make.
- Mentions stir-frying bok choy with ginger for dinner.
- Recommends ginger as an anti-inflammatory phytochemical that can help soothe the gut lining.
- States that ginger can be good for nausea.
- Dr. Hyman recommends Dandelion root.
- Notes that herbs can be helpful for mobilizing toxins, specifically mentioning dandelion root, ginger, cardamon, and cinnamon. Dr. Mark Hyman also states that dandelion greens are one of the most liver detoxifying plants, helping bile flow.
Siim Land · Gentian · uses
- Biohacked his way out of reflux and heartburn using gentian root and artichoke extract, and hasn't needed reflux medications for about eight years.
- Mentions ginger as a compound that can increase autophagy, but notes it doesn't come close to exercise in effectiveness.
- States that ginger lowers body weight in people who are overweight or have high inflammation.
- Recommends having ginger tea in the evening as it has autophagy-regulating effects.
- Drinks ginger tea in the evening.
- Places Ginger in the 'good' tier, noting evidence that it helps with weight loss and digestion, though its effects are not very significant.
- Recommends ginger for metabolic health, especially for insulin resistance and dyslipidemia.
- Recommends ginger for general longevity, stating it has been seen to extend lifespan in animals and improves inflammation, might support weight loss, and joint health in humans, though with slightly less evidence than curcumin.
- Recommends Ginger for longevity, highlighting its anti-inflammatory and antioxidant properties, and its benefits for digestion.
- Notes that Ginger has evidence for aiding weight loss and digestion, though not significantly. He places it in the 'good tier'.
- Discusses Ginger as a supplement.
- Mentions dandelion extract as a cholagogue and choleretic that helps squeeze the gallbladder, mobilizing bile acid into the digestive system for detox.
- Siim Land, Inca, started using dandelion around the same time her liver values improved, noting that it works through a similar pathway as NAC.
Ben Greenfield · Gentian · recommends
- Ben recommends Gentian bitters for naturally increasing HCL production.
- Advises patients to stop ginger before surgery because it can act as a med or antiplatelet agent.
- Used to take dandelion root pre-show as a bodybuilder as a pretty potent a med to get a lot of fluids out of the body.
- Recommends root spices like ginger for use on the AIP diet.
- Recommends anti-inflammatory spices like turmeric, ginger, and garlic, often seen in a Mediterranean approach, to help with inflammation and fat loss.
- He recommends sprinkling ginger into food and rotating it into the diet on a regular basis to induce a hormetic response.
- Recommends ginger for gas and gastrointestinal motility issues, suggesting chewing on ginger candies or ginger root, or making ginger tea.
- Mentions covering the hidden benefits of ginger.
- Uses ginger frequently in various forms, including powder in cooking, dry ginger for travel, and boiling organic ginger root for tea, noting its positive impact on triglyceride levels, plasma cholesterol, LDL oxidation, and atherosclerosis.
- Mentions ginger as an ingredient in the NOVOS supplement, which has decent human research for cellular longevity and staving off DNA damage.
- Ben mentions combining dandelion root extract with carbohydrate loading to excrete excess water for a ripped look.
- Ben mentions that a daily dose of 1-4g of ginger is an easy hack for high triglycerides.
- Uses ginger root when traveling as a cheap digestive hack, boiling it in water every morning to sip throughout the day and chewing on the softened pieces, which is fantastic for gut health.
- Recommends dandelion extract (leaf or root) for its clinically proven ability to reduce heavy-metal build-up and enhance detoxification by preventing glutathione depletion.
Dr. Eric Berg · Ginger · recommends
- Suggests that ginger is an easy addition to a daily routine that may support digestion, inflammation, and healthy blood sugar levels.
- Recommends consuming ginger every single day for its benefits on digestion, inflammation, skin, blood sugar stability, and potential fat loss.
- Mentions ginger as a food that black cumin seed oil outperforms in reducing inflammation.
- Lists ginger as an epigenetic factor that may help with cancer prevention.
- Recommends ginger as it works to reduce inflammation.
- Asks if the audience knows about the benefits of consuming ginger.
- Highlights amazing benefits of ginger.
- States that dandelion greens are good for the liver.
- Recommends ginger as a natural remedy for period pain.
- Notes that ginger was comparable to meds in a randomized control study for menstrual cramps.
- Recommends ginger as an herb that can increase the contraction of the gallbladder.
- Recommends dandelion tea, stating it is good and acts as a med to get rid of excess fluid.
- Discusses dandelion as a common weed that may help reverse liver damage, assist with liver inflammation, and potentially reverse cirrhosis. They suggest eating dandelion greens and flowers to get these health benefits, recommending a dandelion salad or incorporating them into a greens mix, or roasting or sautéing them.
- Recommends dandelion as one of the best natural remedies for everything to do with the liver, as well as kidney problems, inflammation, and blood sugar issues, suggesting to put the greens in a salad or lightly steam them.
Thomas DeLauer · Ginger · neutral
- Mentions that Dose Daily contains organic ginger root powder.
- States that Dose Daily includes organic dandelion root extract as an ingredient.
- Uses ginger oil, an ingredient in Curcumin Gold, stating it helps modulate inflammation within the gut.
- Recommends ginger, explaining that it contains components that allow GLUT4 receptors to disperse more heavily throughout a cell, which helps absorb glucose and reduces blood sugar.
- Recommends dried ginger powder for insulin resistance, stating that it hits all three pathways simultaneously and significantly lowers fasting blood sugar and reduces insulin resistance.
- Recommends dried ginger for fat burning, stating that it activates a fat-burning receptor and drives up adrenaline and fat loss without needing caffeine or stimulants. He suggests taking 1 to 5 grams pre-exercise or in a fasted state, or adding it to coffee, electrolytes, or tea.
- Recommends ginger powder, stating that it hits inflammation from two different angles simultaneously, suppressing enzymes that produce pain and swelling, and suppressing nuclear factor kappa B to block inflammatory gene expression. He suggests using 3g per day consistently for 6 to 8 weeks for muscle soreness reductions.
- Recommends dandelion as a bitter green for the gallbladder.
- Mentions that Dose Daily, which he recommends for liver support, contains organic ginger root powder.
- Mentions that Dose Daily, which he recommends for liver support, contains organic dandelion root extract.
- Recommends using 1 to 3 grams of dry ginger powder daily, especially in a fasted state, before workouts, or with carbohydrate-heavy meals, as it can significantly reduce fasting blood glucose and has a ripple effect on insulin resistance and visceral fat.
- Recommends ginger, noting that it contains gingerols and helps increase GLUT4 translocation, which is beneficial for insulin resistance.
- Recommends adding a small amount of dandelion greens to meals, as they slow gastric emptying and improve insulin function by working on a hormonal gut incretin axis.
- Recommends ginger as it speeds gastric emptying, leading to less food fermentation and reduced bloating.
Andrew Huberman · Ginger · neutral
- Discusses a study where people who had taken powdered ginger were less judgmental because their stomachs were calmed, noting that ginger calms the stomach.
- Asks if ginger can increase metabolism and states that apparently, it can.
- Conducted a study on ginger powder dissolved in warm water, which significantly elevated the thermic effect of food over a 6-hour period, suggesting it could boost energy expenditure.
- States that there are good, unbiased peer-reviewed studies showing that 1 to 3 grams of ginger can cause a notable reduction in nausea.
- Mentions dandelion as something that can help with detox pathways.
- Mentions ginger as having some potential benefit for inflammation, but notes it's not typically used unless in very specific circumstances like an injury.
- Recommends ginger for reducing nausea.
- Ginger can cause a notable reduction in nausea, with good data from 11 peer-reviewed research studies showing its effectiveness at a dose of one to three grams.
Dr. Rhonda Patrick · Ginger · uses
- Likes adding ginger to bone broth for flavor, warmth, and its anti-inflammatory compounds.
- Takes a ginger capsule, which seems to improve his digestion.
- Tim Ferriss consumes ginger with turmeric and black pepper in tea to counteract unnecessary inflammation.
Dave Asprey · Ginger · recommends
- Recommends ginger as a midwife remedy to help with nausea during pregnancy.
- Recommends bitter foods like dandelion greens to naturally stimulate the gallbladder to contract and release bile.
- Suggests buying dandelion greens at the grocery store as a way to choose less commercial products.
- States that ginger pain is the toxin that causes gum inflammation and periodontitis, and increasing the activities of other microbes can keep it in control.
- Mentions that ginger is one of the adaptogens they ferment in their scoby.
- Recommends buying dandelion greens and other funky, less commercial products at the grocery store.
- Recommends buying dandelion greens at the grocery store as part of a strategy to eat more 'funky' and less commercial products for better health.
- Dave Asprey notes that Farmers Juice uses ginger.
- Recommends getting dandelion greens as a way to pick out things at the grocery store that aren't big commercial products.
- Tiffany Haddish drinks ginger turmeric tea every day.
- Mentions taking ginger as part of his typical supplementation.
- Mentions that Capex includes dandelion root extract to help with fat digestion by stimulating bile production, which is crucial for breaking down fat.
- Recommends ginger as a natural remedy for inflammation.
- Discusses using ginger.
Bryan Johnson · Ginger · uses
- Includes three capsules of Ginger in his Blueprint stack.
- Includes 3g of ginger in his Super Veggie for a variety of benefits including liver, pancreas, artery health, and digestion.
- Includes ginger in his Super Veggie meal, which he eats at 7 AM.
- Includes ginger in his daily 'Super Veggie' breakfast for its nutrient density.
- Uses ginger in his Super Veggies.
RAL Summary
Members OnlyTier 4 for Gallbladder and Fat Digestion
The tier rests on 7600 reviews at 95% positive, but the review search found no customer reviews of Loomis Enzymes Lgl on any site and only competing brands on Amazon, so those counts are not about this product. Its reviews are set aside, so it is graded on its studies alone. Animal studies support Gentian, but there are not yet enough reviews to confirm it (0).
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 1 of the 9 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system, Liver and gallbladder
Combine with: Lipase and amylase are digestive enzymes that help break down dietary fats and starches, which supports fat digestion and post-meal comfort when bile flow is sluggish or the gallbladder is compromised. Note that the formula appears to lack protease and bile-directed ingredients, so it is only a partial gallbladder formula. Pairing it with ox bile or purified bile salts can directly aid fat emulsification, which is especially helpful for people without a gallbladder or with thick bile. Taurine, phosphatidylcholine, and choline support bile composition and flow. Herbs such as artichoke leaf, dandelion root, milk thistle, and turmeric are traditionally used to stimulate bile production and support liver and gallbladder function. A broad-spectrum enzyme with protease can help with protein digestion, and magnesium can support regular bowel movements. Take enzymes at the start of meals. Anyone with gallstones, bile duct obstruction, pancreatitis, or persistent upper-abdominal pain should consult a healthcare provider before using bile or choleretic herbs.
Possible side effects: No side effects were reported in the studies. The label carries a cascara sagrada warning about loose stools and abdominal pain.
Supplement Facts
Butternut 160 mg · Cascara Sagrada 120 mg · Dandelion 100 mg
| Butternut | 160 mg | † |
| Cascara Sagrada | 120 mg | † |
| Dandelion | 100 mg | † |
| Gentian | 60 mg | † |
| Ginger | 20 mg | † |
| Proprietary Enzyme Blend | 53 mg | † |
Other ingredients: Cellulose, Water, Phytase.
Directions: Directions for use: Take 2 capsules, 3 times daily after meals or as directed.
Barcode (UPC) 697706043211 · Label source: NIH label database · Report a label change
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More gallbladder and fat digestion products
Members OnlyThe highest ranked for the same goal
Graded November 7, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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