Nature Made Magnesium Glycinate 200 mg Review

This Amazon listing sells Nature Made Magnesium Glycinate 200 mg per Serving in a 60 count bottle of capsules, described as a 30 day supply. The product is presented as a high absorption magnesium supplement for muscle, heart and bone support, also labeled as Magnesium Bisglycinate Capsules. The page says the product helps convert food into cellular energy and supports muscle relaxation, bone health, heart health and nerve health. It describes Magnesium Glycinate as gentle on the stomach and as a highly bioavailable, chelated form of magnesium. The listing states that magnesium helps support the production of melatonin. Directions say adults take two Magnesium Bisglycinate Capsules daily with water and a meal to aid absorption. The product is described as gluten-free, with no added color and no artificial flavors. The page calls it the number 1 Pharmacist Recommended Vitamin and Supplement Brand, marked with an asterisk. The product specifications list the item form as capsule, the primary supplement type as magnesium, the flavor as unflavored, and the diet type as gluten free. The item weight is listed as 3.61 ounces, with 1 item and a unit count of 60. The features section adds that the product offers better absorption and better GI tolerance than other magnesium forms such as magnesium oxide, and that it is 100 percent chelated magnesium glycinate. The page notes that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure or prevent any disease. The manufacturer is listed as Pharmavite, and the brand is Nature Made. The sold-by and ships-from details name Amazon.com, and the item is non-returnable due to food safety reasons. Other sizes shown on the page are 110 count and 180 count bottles of the same product name. The page shows a rating of 4.6 out of 5 stars from 22,712 ratings. No star histogram or written customer reviews are visible in the scraped text.

Product Focus: SleepAlso covers:BrainMuscles and joints
Tier ⓘ
Tier 4 · Rank 3
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 3 within Tier 4 for Sleep; 20 of 44 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
51 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
81% of 24,483
Biohacker Mentions
6 of 10
Cost per month
$12

Study, Trial or Testing Result Summary

Members Only53 human studies · 29 improved

6 of these 53 human studies gave magnesium by drip, not by mouth.

53 human studies29 improved18 no effect42,801 people studied

This product gives 200 milligrams of magnesium as magnesium glycinate, close to the 226 milligrams that worked in one sleep trial, so it counts as a full dose. The evidence for sleep is mixed. A pooled analysis of three placebo-controlled trials in 151 older adults with insomnia found people fell asleep about 17 minutes faster, but the gain in total sleep was not clear and the evidence was low quality [1]. In 216 people with night leg cramps, 226 milligrams at bedtime for 60 days improved sleep quality more than placebo [2]. In 46 older adults with insomnia, 500 milligrams daily for 8 weeks improved sleep time and time to fall asleep [3]. Other trials found no benefit: 320 milligrams for 7 weeks in 100 poor sleepers did not beat placebo [4], and a 4-week trial in 94 older adults found no difference from placebo [5]. A review of 12 trials called the results inconsistent and low certainty, and did not support magnesium as a routine insomnia treatment [6]. Note that the trials used other forms of magnesium, such as oxide and citrate, not glycinate. Animal and cell studies are never counted.

See all 53 studies →Hide the studies

Review Totals and Summary

Members Only24,483 reviews · 81% positive
24,483 reviews · Amazon 22,712 · Walgreens 714 · Walmart 463 · CVS 430 · Metro Market 82 · Kroger 82
81% positive5% neutral14% negative

This Nature Made Magnesium Glycinate 200 mg product has received about 23769 ratings across various stores, with 69% of them being 4 or 5 stars. Overall, customers find it effective for several health benefits, though some common complaints exist regarding the capsule size and packaging. **What buyers say it did for them:** Many customers report significant benefits from taking these capsules. A frequent theme is improved sleep and evening relaxation, with users noting it helps them "fall asleep and stay asleep without a hangover" and "helps me to relax in the evening." It is also praised for being "Great for your stomach," with many finding it gentle and not causing upset, even when taken at night. Some reviewers highlight its effectiveness in preventing and relieving leg cramps, with one stating it "helps with my leg cramps." Other reported benefits include maintaining regularity, recuperating from muscle soreness, and even improving overall mood, with one user noting, "My overall mood has been much better." **Complaints:** The most common complaint revolves around the size of the capsules, with many finding them "Too big to swallow" and wishing the size was disclosed before purchase. Another recurring issue is a discrepancy regarding the USP verification label; some customers received bottles without the label despite website images showing it, leading to concerns about "false advertisement." Less frequent but notable complaints include receiving bottles with "packaging was damaged" or containing "a lot of powder in the bottle." One long-time user reported a possible reformulation, experiencing a "taste and smell like it was musty" and subsequent digestive upset, which was "very different than my past experiences." **Taste, smell, pill size, and form:** The product is sold as capsules. While some reviewers find the "capsules are tasteless" and have "no noticeable odour," others, as noted in store summaries, describe the taste as mild or pleasant, but some found it bitter or overpowering. One reviewer specifically mentioned a "musty or mildew like" taste and smell. As for size, it's a mixed bag: many find the pills "huge" and difficult to swallow, while others state they are "easy to swallow." It's worth noting that some reviews mentioned a gummy version of the product, but this summary focuses solely on the capsules. **Value for money:** Many customers consider this product to offer good value. Reviewers frequently describe it as a "Good Price for a good quality" magnesium glycinate, and store summaries confirm that the price is reasonable for a quality product. **Who it seems to suit and who it did not:** This magnesium glycinate appears to suit individuals seeking help with sleep, evening relaxation, leg cramps, and digestive regularity, especially those who prefer a supplement that is gentle on the stomach. It is particularly well-received by those who find the capsules easy to take despite their size. However, it may not be suitable for individuals who struggle with swallowing large pills or those who are sensitive to potential taste or smell variations. Customers concerned about packaging accuracy, such as the USP label, might also find these issues problematic.

Biohacker Summary

Members Only6 of 10 recommend it
6 of 10 biohackers on our panel recommend it

Most of the panel backs magnesium: five recommend it, four say they use it, and one warns about labels, while a couple stay neutral. The main reason is sleep, with several taking it in the evening, one suggesting 90 minutes to 2 hours before bed, and others also citing stress, muscle recovery, blood pressure and bone health. Forms vary: glycinate is favored by three of them for sleep and calm, while threonate is the most common choice among those who give a dose, usually 400 mg before bed. Daily amounts mentioned run from 300 mg at bedtime up to 400 to 600 mg a day, and one person aims for about a gram, with some pairing it with sodium and potassium in electrolyte drinks. The one caution is that some labels list the weight of the whole compound rather than the actual magnesium, which can make the dose look much larger, and one panelist adds that evidence for sleep benefits is mixed.

See all 10 biohackers →Hide the biohackers
  • Dr. Rhonda Patrick · Magnesium · recommends
    • 8 Nov 2026 · recommends · Instagram ↗
      Explains that magnesium helps the body activate and metabolize vitamin D, and that magnesium intake has been associated with lower odds of vitamin D deficiency and insufficiency.
    • 6 Nov 2026 · neutral · Instagram ↗
      Mentions that getting too little magnesium may play a role in declining testosterone levels.
    • 3 Nov 2026 · recommends · X ↗
      Recommends getting enough magnesium, around 300–400 mg daily from diet and supplements, as it is an essential cofactor for vitamin D metabolism. Magnesium glycinate is a good form.
    • 1 Nov 2026 · neutral · YouTube ↗
      Mentions magnesium as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 31 Oct 2026 · neutral · YouTube ↗
      Explains that magnesium helps control blood pressure by boosting the production of substances that relax blood vessels and improve cardiovascular health, citing a meta-analysis that found magnesium supplementation at an average dose of 368 mg per day notably lowers both systolic and diastolic blood pressure.
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
  • Dr. Eric Berg · Magnesium · recommends
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends Magnesium glycinate, noting its high absorption rate compared to magnesium oxide, and its support for energy, sleep, muscle relaxation, and vitamin D function.
    • 7 Nov 2026 · neutral · Instagram ↗
      Dr. Berg states that when nutrients like magnesium are too low, fatigue and weakness can follow.
    • 6 Nov 2026 · recommends · Podcast ↗
      Recommends focusing on magnesium to support stronger bones if a neck hump is associated with osteoporosis.
    • 6 Nov 2026 · neutral · Instagram ↗
      Explains that leg and calf cramps are most often caused by low magnesium, with leafy greens being a top source.
    • 6 Nov 2026 · recommends · YouTube ↗
      States that magnesium is a cofactor that allows B1 to work more efficiently.
    • 4 Nov 2026 · recommends · YouTube ↗
      States that magnesium is the most important mineral for energy production, as one cannot make energy without it.
    • 1 Nov 2026 · neutral · YouTube ↗
      Magnesium is involved in 300 to 600 enzyme reactions, acts as a biological brake pedal, is the master controller over calcium, and is involved in making ATP, the energy currency of the body. It takes energy to go to sleep, and magnesium is required for relaxation and good sleep. Magnesium also helps balance cortisol levels and calm you.
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
  • Thomas DeLauer · Magnesium · recommends
    • 5 Nov 2026 · recommends · YouTube ↗
      Recommends taking magnesium glycinate and threonate at night to act as a brake on the nervous system, block excitatory signaling, help wind down, and support serotonin and melatonin production for better sleep.
    • 4 Nov 2026 · neutral · YouTube ↗
      Mentions that magnesium glycinate also helps a lot with sleep.
    • 2 Nov 2026 · neutral · YouTube ↗
      Mentions that restless leg syndrome is often treated with magnesium, but states that the sensation is actually coming from three other issues.
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 25 Sep 2026 · neutral · Facebook ↗
      Mentions that magnesium in pumpkin seeds relaxes bronchial smooth muscle.
  • Andrew Huberman · Magnesium · recommends
    • 4 Nov 2026 · recommends · Instagram ↗
      Notes that Les Spellman's team includes 'Magnesium timed right' as part of their game plan to optimize recovery in unfavorable conditions.
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 13 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 6 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 22 Jun 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
  • Dr. Mark Hyman · Magnesium · recommends
    • 4 Nov 2026 · recommends · YouTube ↗
      Recommends magnesium breakthrough advanced ten from Biooptimizers, which is their most complete magnesium formula with 10 bioavailable forms and 550 milligrams of elemental magnesium, designed to support restful restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that a lack of magnesium can cause muscles and nerves to malfunction, resulting in muscle weakness, twitching, and cramps.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 16 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
  • Dave Asprey · Magnesium · uses
    • 3 Nov 2026 · uses · Instagram ↗
      Looks at magnesium alongside protein to keep muscle for the long run.
    • 3 Nov 2026 · recommends · YouTube ↗
      Suggests adding magnesium to help keep potassium in the system longer, as they work hand in hand.
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 15 Aug 2026 · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 13 Jun 2026 · neutral · X ↗
      Notes a new study indicating that magnesium is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 17 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 10 Aug 2026 · recommends · YouTube ↗
      Notes that magnesium is important for activating thiamine into its more biologically active form, and a magnesium deficiency can impair blood sugar regulation even with adequate thiamine intake.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
    • 20 May 2024 · uses · YouTube ↗
      Takes magnesium as a straightforward supplement.
    • 28 Feb 2024 · neutral · YouTube ↗
      Mentions that magnesium intake is often super low and impactful on testosterone levels.
    • 11 Dec 2023 · uses · Facebook ↗
      Discusses the important roles of magnesium in the body, how to determine if one might be deficient, the prevalence of magnesium deficiency, and its potential cognitive benefits.

RAL Summary

Members OnlyTier 4 for Sleep

The rules read the magnesium evidence as showing no effect, but more studies found benefit than not and a pooled analysis found modestly faster sleep onset, so the evidence is mixed rather than negative. So it is graded Tier 4, as the studies disagree.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 18 of the 53 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system, Musculoskeletal system

Combine with: To enhance the sleep-promoting effects of Magnesium Glycinate, consider combining it with supplements like Melatonin, which helps regulate sleep-wake cycles, or L-Theanine, known for its calming properties without causing drowsiness. Valerian root or Chamomile can also be synergistic, offering additional natural relaxation and sleep support.

Possible side effects: No major side effects reported in the studies given. Buyer feedback summaries mention large capsules that are hard to swallow and occasional digestive upset.

Supplement Facts

Magnesium 200 mg
Supplement Facts
Serving Size 2 Capsules
Servings Per Container 30
Amount Per Serving% Daily Value
Magnesium (as Magnesium Bisglycinate)200 mg48%

Other ingredients: Hypromellose, Magnesium Stearate, Cellulose Gel, Silicon Dioxide.

Directions: SUGGESTED USE: Adults, take 2 capsules daily with water and a meal.

Label source: Naturemade · Report a label change

Sizes and barcodes: 60 Capsule(s), UPC 0 31604 04313 1 (on market)

Show entire label
The Nature Made Magnesium Glycinate 200 mg label
Magnesium Glycinate 200 mg

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Our articles on this subject

Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.