Thorne Research Deep Sleep Complex Review
Thorne's Deep Sleep Complex is a melatonin-free, non-habit-forming formula designed to quiet a busy mind and support deeper, more restorative sleep with regular nightly use. It combines Maizinol, a standardized corn leaf extract that has been clinically studied to support all phases of the sleep cycle, with L-theanine and chamomile extract to promote relaxation at bedtime and help you wake up feeling refreshed, without next-day grogginess. The product is described as an all-natural option for support of deeper, more restful sleep and clear-headed mornings. The label directs use of 2 capsules taken 60 minutes before bedtime daily, with 30 servings per container. Each serving provides corn extract (leaf) 500mg, L-Theanine 200mg and chamomile extract (flowering top) 100mg. The page says the chamomile is standardized to contain no less than 1.2% apigenin, and that the Maizinol extract from young green corn shoots is standardized to contain 0.2% 6-MBOA, a naturally occurring compound similar to melatonin. The L-theanine is listed as Suntheanine, a patented form. The page lists benefits including promoting relaxation and a smoother drift-off, supporting a healthy stress response at bedtime through cortisol modulation, improving sleep quality and sleep architecture, calming the mind, and resulting in fewer sleep disturbances and less frequent waking. It describes expected timing, with a decrease in stress feelings within 20 minutes, a sense of relaxation within 60 minutes, changes in time to fall asleep within one week of nightly use, and a decrease in anxious feelings after two weeks. The page suggests the product for people who occasionally have trouble falling asleep because of stress, those with high evening cortisol, people who wake often at night, older individuals with lower melatonin, and those who want to wake up refreshed. It cites clinical study figures on the ingredients, including reported gains in total sleep time and sleep quality, and notes that the product is third-party tested and certified to verify label accuracy and to confirm the absence of unsafe levels of contaminants. Warnings state that the product is contraindicated in anyone with a history of hypersensitivity to its ingredients, that pregnant or nursing people should not use it, and that no known adverse interactions were reported at publication. The FAQ notes that people with a known corn allergy should consult an allergist, and that the leaf generally does not carry the same allergens as the kernel.
We don’t sell supplements. We help you make decisions and get the best price.
Lowest prices
We may earn a commission from some store links. How we choose.
Finding the lowest prices at the stores now. This takes a few seconds.
Study, Trial or Testing Result Summary
Members Only55 human studies · 28 improved
4 of these 55 human studies gave the ingredient by inhaler, not by mouth.
Corn leaf extract, the main ingredient, is here at 500 milligrams, a dose that worked in studies. In a trial of 45 adults, 250 or 500 milligrams before bed for 4 weeks increased deep sleep and total sleep time, improved sleep quality scores and lowered stress hormone levels compared with placebo [1]. In 80 healthy adults with trouble sleeping, 28 days of corn leaf extract increased total sleep time and dream sleep and cut time awake during the night [2]. L-theanine is at the studied 200 milligrams. Pooling 19 trials with 897 people, it modestly improved time to fall asleep, daytime tiredness and overall sleep quality [3]. In 30 healthy adults, 200 milligrams daily for four weeks shortened time to fall asleep [4]. Not all trials agree: a blend with 200 milligrams of L-theanine did not help 103 healthy adults [5], and another blend did not help poor sleepers [6]. Chamomile, at 100 milligrams a serving, is below the 400 milligrams that helped older adults' sleep quality [7] unless several servings are taken. Pooled trials found chamomile improved sleep quality ratings but not sleep length [8]. Animal and cell studies are never counted.
See all 55 studies →Hide the studies
- Across 14 trials of 1602 people with insomnia testing valerian, chamomile, kava and wuling, no herbal medicine beat placebo or active treatment on any sleep measure.Herbal medicine for insomnia: A systematic review and meta-analysis.
- Pooling 19 randomized trials with 897 people, L-theanine modestly improved self-reported time to fall asleep, daytime dysfunction and overall sleep quality compared with control.The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
- Across ten trials of 772 adults, chamomile lowered sleep quality scores (better sleep) and often reduced night awakenings, but did not improve sleep length, sleep efficiency or daytime functioning.Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials.
- In 11 trials of 690 critically ill patients, an inhaled blend of lavender, chamomile and neroli oils gave the largest sleep quality improvement versus usual care, though the evidence was rated low certainty.Effect of inhaled aromatherapy on sleep quality in critically ill patients: A systematic review and network meta-analysi…
- Pooling 12 randomized trials, chamomile significantly improved sleep quality, but the single trial on insomnia severity found no significant change.Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep qualit…
- A review of 13 trials with 550 people found L-theanine at 50-900 mg a day, with 200-450 mg seeming best, improved sleep latency, efficiency and perceived sleep satisfaction.Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials.
- In children with ADHD, L-theanine showed a poor response in reducing time to fall asleep and increasing total sleep time, but did increase sleep efficiency.To sleep or not to sleep: a systematic review of the literature of pharmacological treatments of insomnia in children an…
- In this review of children with ADHD and insomnia, the one L-theanine trial reported improvements in time to fall asleep and total sleep duration, and it was well tolerated.Safety, Tolerability and Efficacy of Drugs for Treating Behavioural Insomnia in Children with Attention-Deficit/Hyperact…
- This review of drug treatments for children with ADHD, including L-theanine, reported that most treatments except atomoxetine affected sleep quality, without separating out L-theanine's effect.Association between sleep pattern and pharmacological treatment in children with attention deficit disorder with hyperac…
- In this review of supplements for ADHD, L-theanine improved sleep efficiency but not other sleep measures.Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic …
- In a review of 28 studies of nursing home residents, chamomile extract was among the approaches that showed positive but cautiously interpreted improvements in sleep quality and nighttime sleep.Nonpharmacological interventions to improve sleep in nursing home residents: A systematic review.
- In 108 intensive care nurses (96 finished), a nightly chamomile-lavender oil massage for 4 weeks lowered sleep problem scores more than placebo oil (from 10.41 to 4.69 versus 10.78 to 6.84).The Effect of Aromatherapy on Fatigue and Sleep Quality in Intensive Care Nurses: A Randomised Placebo-Controlled Trial.
- In 103 healthy adults taking an evening blend with 200 mg L-theanine for two weeks, sleep did not improve versus placebo; only the morning adaptogen group improved.Modulating stress and sleep through a multi-compound dietary supplement: a randomized, double-blind, placebo-controlled …
- In 100 stressed adults taking a combination product containing L-theanine for 28 days, daytime dysfunction from sleepiness improved, reaching significance by day 56, though sleep was only an exploratory outcome.Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy I…
- In 98 boys aged 8-12 with ADHD, 400 mg of L-theanine daily for 6 weeks improved measured sleep percentage and sleep efficiency compared with placebo, while time to fall asleep was unchanged.The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorde…
- In 90 patients after bowel cancer surgery, a foot massage with a chamomile-containing oil blend did not improve sleep beyond plain massage; both massage groups beat no massage only on the second day after surgery.The effects of aromatherapy massage given to patients after colorectal cancer surgery on symptom management: A randomize…
- In 80 healthy adults with trouble falling or staying asleep, 28 days of corn leaf extract increased total sleep time, light sleep and REM sleep and reduced time awake after falling asleep compared with placebo.A Randomized, Triple-Blind, Placebo-Controlled, Parallel Clinical Trial Investigating Safety and Efficacy of Corn Leaf E…
- In 80 postnatal women with poor sleep, drinking chamomile tea for 2 weeks reduced physical sleep problems and depression symptoms versus usual care right after, but the benefits were gone by 4 weeks.Effects of an intervention with drinking chamomile tea on sleep quality and depression in sleep disturbed postnatal wome…
- In 80 young adults with insomnia, breathing chamomile oil for 10 minutes daily for 15 days reduced insomnia severity and improved sleep quality more than usual routine.Effects of chamomile oil inhalation on sleep quality in young adults with insomnia: A randomized controlled trial.
- In 80 breast cancer patients having chemotherapy, chamomile oral solution three times a day for four chemotherapy courses improved sleep quality versus placebo (about 4.5 times higher chance of good sleep), though it did not reduce nerve damage or anxiety.Evaluation of the protective effect of chamomile oral solution on the incidence of neurotoxicity caused by paclitaxel in…
- In 64 adults with poor sleep, a blend of L-theanine, lemon balm, valerian and saffron taken for 6 weeks did not improve measured or self-reported sleep more than placebo.Effect of a nutraceutical combination on sleep quality among people with impaired sleep: a randomised, placebo-controlle…
- In 60 elderly people, chamomile extract capsules of 200 mg twice a day for 28 days improved sleep quality significantly more than wheat flour capsules.The effects of chamomile extract on sleep quality among elderly people: A clinical trial.
- In 55 postmenopausal women, a chamomile and angelica combination for 12 weeks cut hot flushes far more than placebo and was reported to ease sleep disturbances, though sleep was not separately measured in the abstract.The immediate effect of natural plant extract, Angelica sinensis and Matricaria chamomilla (Climex) for the treatment of…
- In 50 hospitalized patients with acute leukemia, inhaled aromatherapy (lavender, peppermint or chamomile scent of choice) significantly improved sleep versus placebo in a crossover design.The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia.
- In 46 adults with generalized anxiety disorder, 450-900 mg of L-theanine for 8 weeks did not beat placebo on insomnia severity overall, but people on L-theanine reported higher sleep satisfaction and those with milder insomnia did better.L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled t…
- In 45 adults, 4 weeks of corn leaf extract at 250 or 500 mg a day before bed increased deep sleep and total sleep time, improved sleep quality scores and lowered stress hormone levels compared with placebo.UP165, A Standardized Corn Leaf Extract for Improving Sleep Quality and Mood State.
- In 40 adults with sleep discomfort, a Lactium and L-theanine supplement for 8 weeks showed no difference in sleep questionnaire scores versus placebo, but sleep diaries showed fewer night wakings and earlier bedtimes.Dietary supplementation with Lactium and L-theanine alleviates sleep disturbance in adults: a double-blind, randomized, …
- In 39 adults with poor sleep, a four-week blend containing L-theanine and a milk-protein hydrolysate improved overall sleep quality scores and sleep duration compared with placebo, but only sleep duration and sleep efficiency held up in both analysis methods.Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-C…
- In 34 adults with long-term insomnia, 270 mg of chamomile extract twice daily for 28 days did not significantly change sleep diary measures versus placebo.Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a r…
- In a placebo-controlled crossover trial of 30 healthy adults, 200 mg of L-theanine per day for four weeks reduced sleep latency, sleep disturbance, and meds use compared with placebo.Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized …
- In 30 healthy adults with moderate stress, 400 mg per day of L-theanine for 28 days reduced perceived stress and light sleep and lowered total time asleep compared with placebo, while improving reaction time on a attention test.Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Rando…
- In 30 young women with painful periods, a chamomile and L-theanine drink taken for five days around menstruation reduced daytime dysfunction compared with baseline, but the abstract does not report a sleep quality result against the control drink.Effects of chamomile and -theanine beverage on menstrual pain, menstrual symptoms, mood, and sleep quality in young wome…
- In 17 trained adult men, a nightly drink containing theanine at low or high dose before bed did not meaningfully improve sleep, morning performance or cognition compared with placebo.Minimal Influence of Formulated Nutritional Interventions on Sleep and Next-Morning Physical Performance, Cognitive Func…
- In a double-blind crossover study of 16 adults, a nutritional blend containing L-theanine over three days shortened time to fall asleep, increased total sleep time by about 22 minutes, and improved sleep efficiency compared with placebo.Nutritional Modulation of Sleep Latency, Duration, and Efficiency: A Randomized, Repeated-Measures, Double-Blind Decepti…
- In nine children with autism, a theanine tea produced some improvements, which were more sporadic than those from the gamma-aminobutyric acid tea, and sleep effects of theanine were not clearly reported.A double-blind, placebo-controlled, randomised-designed GABA tea study in children diagnosed with autism spectrum condit…
- In a crossover trial of healthy young women, 50 mg of theanine did not change sleep compared with placebo, but it prevented the rise in night-time waking caused by 30 mg of caffeine.Theanine maintains sleep quality in healthy young women by suppressing the increase in caffeine-induced wakefulness afte…
- In an eight-week placebo-controlled trial in adults with poor sleep, a walnut peptide and L-theanine combination restored sleep duration and improved self-rated sleep quality, though the abstract does not give the number of participants or the theanine dose.Walnut peptide and theanine combination ameliorates sleep disorders: a multi-species study including a human trial.
- In patients with allergic asthma, a herbal tea containing chamomile and seven other herbs improved sleep discomfort, cough frequency, and cough intensity compared with placebo tea.The effect of a herbal water-extract on histamine release from mast cells and on allergic asthma.
- In 105 burn patients, a lavender and chamomile oil massage given before bed for three sessions within a week improved sleep quality compared with usual care.The effect of aromatherapy massage with lavender and chamomile oil on anxiety and sleep quality of patients with burns.
- In 77 nursing home elderly, 400 mg chamomile extract capsules twice daily for 4 weeks led to significantly better sleep quality scores than no treatment.Investigation effect of oral chamomilla on sleep quality in elderly people in Isfahan: A randomized control trial.
- In 56 intensive care patients after a heart procedure, inhaling a lavender, roman chamomile and neroli oil blend 20 times improved sleep quality and lowered anxiety compared with usual nursing care.Effects of aromatherapy on the anxiety, vital signs, and sleep quality of percutaneous coronary intervention patients in…
- In women with sensitive skin, an oral botanical blend containing L-theanine improved self-rated sleep quality at one and eight weeks, though it was combined with ashwagandha and saffron so the theanine effect cannot be isolated.Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study.
- In an open randomized crossover study of 160 adults, 200 mg per day of L-theanine significantly improved sleep problems, with no placebo group included.Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Probl…
- In 20 adults with depression taking 250 mg of L-theanine daily for eight weeks alongside their usual medication, sleep quality scores improved in those not in remission, along with mood and some thinking test scores, though without a placebo group.Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
- In 19 adults with sleep problems, four weeks of 200 mg per day of L-theanine taken with 700 mg of gamma-aminobutyric acid significantly improved overall sleep quality scores, in a single-group study without a placebo.Effects of combined GABA and L-theanine supplementation on sleep quality: an exploratory study.
- In 17 patients with schizophrenia taking antipsychotics, adding 250 mg of L-theanine per day for eight weeks improved sleep quality scores, though the study had no placebo group.Effect of L-theanine on glutamatergic function in patients with schizophrenia.
- This survey of 997 adults in Quebec found that 18.5% had used natural products for sleep in the past year, with chamomile the most popular, but it did not measure whether chamomile improved sleep.The use of natural products for sleep: A common practice?
- In a questionnaire of 202 mothers, 12.3% gave herbal products, including chamomile tea, for children's sleep problems or calming, but the study did not test whether these products worked.Herbal supplement products used by mothers to cope with the common health problems in childhood.
- In dementia patients with insomnia, chamomile essential oil massage raised urinary norepinephrine but did not clearly improve sleep, while a blend that included chamomile raised serum serotonin, suggesting possible sleep benefit.Differences in Neurotransmitters Level as Biomarker on Sleep Effects in Dementia Patients with Insomnia after Essential …
- This literature review of herbal and natural sleep supplements lists German chamomile among them but gives no chamomile-specific result, noting that evidence strength varies widely and larger trials are needed.Herbal and Natural Supplements for Improving Sleep: A Literature Review.
- In sleep-disturbed rats, a 1000 mg/kg dose of a valerian, golden root and L-theanine preparation shortened time to fall asleep but did not change total time awake, deep sleep or dream sleep, and the L-theanine dose alone was not reported.Effect of valerian extract preparation (BIM) on the sleep-wake cycle in rats.
- In rats given caffeine, L-theanine at 22.5 and 37.5 mg/kg partly restored deep sleep, but it did not reduce caffeine-induced wakefulness and higher doses did not help, so this animal result is not a human finding.L-theanine partially counteracts caffeine-induced sleep disturbances in rats.
- In mice and rats, a combination of 100 mg/kg gamma-aminobutyric acid and 20 mg/kg L-theanine shortened sleep onset and lengthened sleep more than either ingredient alone, but this was an animal study and not a human trial.GABA and l-theanine mixture decreases sleep latency and improves NREM sleep.
- In mice, L-theanine alone and combined with a spearmint extract lengthened sleep and shortened the time to fall asleep when given with sleep-inducing drugs, though the study does not report human results and the dose was not stated.L-theanine and Neumentix mixture improves sleep quality and modulates brain neurotransmitter levels in mice.
- In mice, L-theanine did not independently change the stimulating effect of a green tea extract, and the study measured arousal rather than improved sleep in people.The polyphenol/caffeine ratio determines the arousal-inducing properties of the green tea ethanol extract.
Review Totals and Summary
Members Only755 reviews · 66% positive
Across the stores the Thorne Research Deep Sleep Complex carries about 302 ratings, and opinion is split. Most buyers who rate it give 4 or 5 stars and describe deeper, more refreshing sleep. A sizeable minority say it did nothing or made their sleep worse. This summary covers the capsules only; one review on the Thorne.com page seemed to describe a gummy and was left out. **What buyers say it did for them:** Happy buyers describe deeper sleep and waking up rested. One says, "I have had the best 40 nights of sleep in a row." Another reports "waking up more rested than before." A 41-year-old found that "middle of the night awakenings have lessened" and noticed calm and sleepiness about an hour after taking it. One user saw fewer bathroom trips overnight. Several mention no grogginess in the morning: "no grogginess the following morning." **Time to work:** Some say it needs patience. One says they were "almost a month into taking" it before sleep improved, and another says "You need to give them a chance to work." Others did not get there. One user tracking sleep with an Oura ring saw no significant difference so far and was waiting to finish the 30-day supply. **What they complain about:** The main complaint is that it simply did not work. Typical comments are "there was no improvement in my sleep" and "It just hasn't worked." One buyer found it helped at first, with 4-5 hours of unbroken sleep, but the effect faded after a few weeks. Another said it "seemed to disturb my sleep all night," with restless sleep on both of two tries. One buyer had an upset stomach that lasted a couple of days. The Thorne.com summary notes no written comments there about digestion, so the stomach complaint appears only in the individual reviews. **Taste, smell, pill size or form:** Reviewers did not comment on taste, smell or capsule size. The Thorne.com page summary likewise reports nothing on these points. **Value for money:** Cost came up once. A buyer who finished the bottle without benefit called it "obviously expensive af." Another happy buyer re-ordered and said they would keep buying it "for life," which suggests those it helps find it worth the price. **Who it seems to suit, and who it did not:** It seems to suit people who want a melatonin-free option and who pair it with good sleep habits, such as limiting screens before bed, exercise and healthy eating. A post-menopausal woman said it was the "first thing that has helped me." Another buyer combined it with magnesium and tart cherry and found the mix beneficial. It did not suit people with long-standing trouble staying asleep who had already tried other aids, and at least one such buyer saw no lasting change. Those who felt nothing, or felt worse, were in the minority of star ratings but were vocal in the written reviews. **Bottom line:** Results vary widely. If you try it, expect to give it several weeks, and be aware that some buyers got no benefit at all.
Biohacker Summary
Members Only7 of 10 recommend it
Only chamomile, a smaller ingredient in this product, drew comments, and seven of the ten panelists spoke about it. Six of them recommend or use it, mainly to wind down, fall asleep, and ease anxiety or racing thoughts at night. Most take it as evening tea, often a couple of hours before bed, though one favors a supplement form and another likes extract or a cup after a meal. Some also link it to calming effects, to autophagy, and to blood sugar and cortisol. Cautions came from one panelist who said it is too weak for severe mental health struggles but may suit very mild anxiety, and from another whose daughter got no help from chamomile drops for night terrors.
See all 7 biohackers →Hide the biohackers
Dr. Eric Berg · Chamomile · recommends
- Dr. Eric Berg recommends Chamomile Tea to help reduce kidney and gallstones.
- Notes that Wikipedia states there is insufficient evidence to recommend the use of chamomile for treating dysmenorrhea.
- Recommends chamomile tea because it contains apigenin, which decreases CD38 cells, helping to preserve NAD in mitochondria and support energy extraction.
- Recommends chamomile tea as a great option to help wind down for sleep.
- Recommends chamomile tea for lowering cortisol and stabilizing blood sugar by directly supporting the cells in the pancreas.
- Suggests chamomile tea as an alternative to parsley for increasing NAD.
- Mentions chamomile tea as a food that can be consumed.
- Highly recommends consuming certain herbs like chamomile, as farnesol is found in them, to help prevent or manage Parkinson's disease.
- Mentions chamomile tea as another good option for nausea.
- Mentions that apigenin can be found in chamomile tea.
Siim Land · Chamomile · neutral
- Mentions getting a 'glycine + chamomile tea buzz too hard', implying a connection to sleep or relaxation.
- Recommends having chamomile tea in the evening as it has autophagy-regulating effects and is part of his perfect evening tea.
- Warns that chamomile is ludicrous for people with severe mental health challenges, as it's not potent enough, but might be interesting for those with very low-grade anxiety.
- Drinks chamomile tea 2 hours before bed, noting its anxiolytic properties and ability to improve sleep.
- Drinks chamomile tea in the evening.
- Drinks chamomile tea after dinner, noting its anxiolytic effects and its ability to help empty the bladder as a med.
- Mixes 3 grams of glycine with chamomile tea before bed, stating that chamomile tea alone can improve sleep due to its calming effects and helps empty the bladder.
- Siim Land, Inca, started using chamomile around the same time her liver values improved, noting that it works through a similar pathway as NAC.
- Says he likes to drink chamomile tea after his meals because it lowers the glycemic response and improves digestion.
- Recommends chamomile tea for its ability to lower blood sugar levels, citing a study where drinking it three times a day after meals resulted in significant reductions in hemoglobin A1c and insulin levels.
Thomas DeLauer · Chamomile · recommends
- Recommends a simple bag of chamomile tea in a nighttime drink, noting it acts as a sedative to help fall asleep.
- Recommends chamomile and lemon balm as hugely beneficial for a sedative-like effect that can make one feel calmer, especially if tart cherry juice is avoided due to sugar content.
- Recommends chamomile in supplement form for sleep, noting its potent, tranquilizer-like effect that binds to Gaba A, helping people wind down and relax a few hours before bed.
- Recommends chamomile for sleep and general anxiety disorder, noting it binds to a med receptor and acts like a sedative.
- Discusses a study where chamomile tea decreased sleep latency by 16 minutes in insomniacs, explaining that chamomile binds to a med receptor, similar to a med, to induce sedation.
- Recommends chamomile for people over 40 who are under a lot of stress and not sleeping well, as it can improve general anxiety disorder and promote sedation without negatively impacting sleep quality.
- Recommends concentrated chamomile tea for sleep, suggesting a four-ounce serving before bed to get the calming effect without excessive fluid intake, noting its effectiveness for sleep quality and anxiety due to apigenin binding to a med receptors.
- Recommends chamomile for sleep, especially after a busy or stressful day, due to its sedative-like effect, but cautions that it can cause a fuzzy brain the next day.
- Recommends chamomile tea, mentioning its use in his popular apple cider vinegar nighttime recipe and noting that it's affordable at Dollar Tree.
- Includes chamomile tea in his nighttime apple cider vinegar drink.
Andrew Huberman · Chamomile · uses
- Mentions chamomile extract as one of the clinically supported ingredients that can help you fall asleep, stay asleep, and wake up feeling more refreshed, and he has worked with AG1 to create a product that includes it.
- Mentions Chamomile extract as a clinically supported ingredient that can help people fall asleep, stay asleep, and wake up feeling more refreshed.
- States that chamomile extract is a clinically supported ingredient that can help one fall asleep, stay asleep, and wake up feeling more refreshed.
- Mentions chamomile extract as one of several clinically supported ingredients that can help people fall asleep, stay asleep, and wake up feeling more refreshed.
- Likes chamomile tea after a meal.
- Mentions that chamomile tea is often suggested for de-stressing, but implies it's not always the appropriate response to stress, especially when preparing for a challenge.
- Notes that chamomile extract is a clinically supported ingredient that can help people fall asleep, stay asleep, and wake up feeling more refreshed.
- Andrew Huberman mentions chamomile extract as one of the things that can be taken to improve sleep.
- Includes chamomile extract among clinically supported ingredients for improving sleep quality.
Dr. Rhonda Patrick · Chamomile · recommends
- Recommends Chamomile as a sleep supplement that promotes relaxation and reduces nighttime awakenings, offering meaningful improvements to sleep quality.
- Mentions chamomile as one of the calming things that can be helpful for people who need a little bit of calming and relaxation to promote sleep, even if it doesn't technically do anything on the sleep side.
- Recommends drinking chamomile tea at night before bed for sleep quality, as it is rich in apigenin and has some evidence to support its benefits.
Ben Greenfield · Chamomile · recommends
- Suggests using chamomile as a compound to help shut down hardwired dopamine firing pathways for those with ruminating thoughts at night.
- Ben Greenfield recommends chamomile as an herbal supplement for insomnia.
- Mentions chamomile powder as part of Dr. Mercola's autophagy tea.
- Ben recommends Chamomile as part of a combo to increase cellular autophagy.
- Mentions chamomile as part of a nighttime autophagy powder.
- Takes Chamomile at night as part of an autophagy mimicking stack.
- Mentions chamomile as a GABA precursor that, when combined with CBD, helps him achieve deep sleep, specifically mentioning chamomile tea.
- Recommends keeping chamomile powder or tea next to the bed and sipping on it if you wake up during the night.
- Uses 1/2 teaspoon of chamomile powder as part of his 'autophagy tea' before his nightly fast.
- Uses organic chamomile tea because it is high in apigenin, a flavonoid that inhibits CD38, an ectoenzyme that consumes NAD+.
Dr. Mark Hyman · Chamomile · recommends
- Recommends chamomile as an herbal supplement for deep sleep and relaxation, especially for those who are tired, wired, and stressed.
- States that chamomile tea helps with anxiety and is calming.
- Mentions chamomile as an herb that can be helpful for sleep.
- Suggests that herbs like chamomile can be very helpful for sleep.
- Dr. Mark Hyman's daughter was given chamomile drops for night terrors, but they didn't help.
- Recommends an herbal formula for sleep that includes chamomile, passion flower, valerian root, ashwagandha, rhodiola, and other adaptogenic herbs to manage adrenal function and relax the brain.
- Tried chamomile drops for her daughter's night terrors, but they did not help.
- Suggests supporting sleep with chamomile extract.
- Dr. Mark Hyman's daughter was given chamomile drops to help with night terrors, but they did not work.
- Recommends chamomile tea as an alternative to alcohol for unwinding and managing stress levels.
RAL Summary
Members OnlyTier 2 for Sleep
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Nervous system, Endocrine system
Combine with: For adrenal support, pair this product with adaptogens such as ashwagandha (KSM-66 or Sensoril) to help moderate elevated cortisol, or rhodiola rosea for fatigue and stress resilience, ideally taken in the morning. Vitamin C, pantothenic acid (B5), and a B-complex with methylated B6 and B12 support adrenal hormone synthesis and energy metabolism. Phosphatidylserine taken in the evening may help blunt an excessive evening cortisol rise, which complements the sleep-focused magnesium and L-theanine. Omega-3 fatty acids and vitamin D add general stress and inflammation support. Licorice root should be used cautiously and avoided with high blood pressure. Check with a healthcare provider before combining supplements, especially if you take medications.
Possible side effects: One reviewer reported an upset stomach lasting a couple of days and another reported restless, disturbed sleep; the studies given report no major side effects.
Supplement Facts
Corn extract † 500 mg · L-Theanine†† 200 mg · Chamomile extract 100 mg
| Corn extract (leaf) (Zea mays)† | 500 mg | † |
| L-Theanine†† | 200 mg | † |
| Chamomile extract (flowering top) (Matricaria recutita) | 100 mg | † |
Other ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Calcium Laurate, Silicon Dioxide.
Directions: Suggested Use: Take 2 capsules 60 minutes before bedtime or as recommended by your health-care practitioner.
Barcode (UPC) 693749015826 · Label source: Reverseagelab · Report a label change
Show entire label

More sleep products
Members OnlyThe highest ranked for the same goal
Read more
Our articles on this subject
- Melatonin vs Magnesium for Sleep: What the Studies ShowArticle · Nov 3, 2026
- Best Supplements for Sleep and the Habits That Matter MoreArticle · Jun 15, 2026
Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
Privacy policyConsumer health dataAffiliate disclosureTermsDo Not Sell or Share My Personal InformationCookie settings

