Nootropics Depot Vignatex Capsules Review

Product Focus: Healthy AgingAlso covers:BrainImmune systemHeart
Tier ⓘ
Tier 3 · Rank 26
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 26 within Tier 3 for Healthy Aging; 134 of 215 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
52 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
90% of 119
Biohacker Mentions
0 of 10

Study, Trial or Testing Result Summary

Members Only1 human studies · 1 improved
1 human studies1 improved

No study in people has tested this product, or either of its ingredients at the dose in it, for reversing aging or for cell and genetic repair. Passionflower is taken at 500 milligrams a day. Its only support for this goal comes from animal studies. In mice with a Parkinson's disease model, passionflower extract lowered inflammation and oxidative stress signals in brain support cells, improved markers of the cell's energy centers, restored markers of new nerve cell growth, and improved movement [1]. In rats with a testicle twisting injury, the extract improved overall antioxidant balance, lowered an inflammation signal and markers of cell death, and helped preserve tissue, though several other oxidative stress measures did not change [2]. It is not known whether these results apply to people. Mung bean extract is present at only 500 milligrams a day, far below the 10 to 15 grams of mung bean protein used in the one human trial. In that six week trial, healthy adults aged 45 to 60 had higher antioxidant enzyme activity, lower inflammation markers, and better blood vessel widening than at the start [3]. No study has measured biological age for either ingredient. Animal and cell studies are never counted.

See all 1 studies →Hide the studies

Review Totals and Summary

Members Only119 reviews · 90% positive
119 reviews · Google Shopping 119
90% positive0% neutral10% negative

Extensive customer reviews and qualitative feedback are currently being aggregated for this product. Check back soon for a detailed sentiment analysis.

Biohacker Summary

Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it

Passionflower is the main ingredient, and four of the five panelists who spoke about it recommend it, while the fifth was neutral and simply noted how it works. The most common reason is sleep and relaxation, especially for people who feel tired, wired, and stressed, and two panelists said it may raise GABA, a calming brain chemical. One recommended it as a calming tea, one as an extract to use in place of alcohol, and one for sleeping in a fasted state, while another suggested it for losing belly fat after menopause. No one gave a dose, no one named a pairing, and no one cautioned against it or said they stopped taking it. Mung bean is a smaller ingredient in this product, and the panelists who spoke about it favored sprouted or cooked mung beans as a nutritious food.

See all 5 biohackers →Hide the biohackers
  • Dr. Mark Hyman · Passionflower · recommends
    • 1 Nov 2024 · recommends · YouTube ↗
      Recommends passionflower as an herbal supplement for deep sleep and relaxation, especially for those who are tired, wired, and stressed.
    • 22 Mar 2024 · Mung Bean · recommends · YouTube ↗
      States that mung beans are good legumes.
    • 3 Dec 2021 · recommends · YouTube ↗
      Suggests using herbs like passionflower for sleep.
    • Date not recorded · Mung Bean · recommends · Website ↗
      Recommends incorporating sprouted mung beans into one's diet, as germination activates the seed's biological potential and can make certain nutrients more available.
  • Thomas DeLauer · Passionflower · recommends
    • 26 Jun 2024 · recommends · YouTube ↗
      Recommends passionflower tea as a calming tea that is often overlooked.
    • 21 Sep 2021 · Mung Bean · recommends · YouTube ↗
      Recommends sprouted mung beans, noting that sprouting them for eight days increases vitamin C content by 24 times and flavonoid content by 7 times, making them a nutritious, low-carb, high-fiber, and low-phytic acid option.
  • Dr. Eric Berg · Passionflower · recommends
    • 17 Nov 2023 · recommends · Podcast ↗
      Recommends trying passionflower to help lose belly fat after menopause.
  • Ben Greenfield · Passionflower · recommends
    • 31 Jan 2019 · recommends · YouTube ↗
      Recommends passionflower as a helpful supplement for sleep in a fasted state, noting it can increase GABA production.
    • 25 Oct 2018 · recommends · Podcast ↗
      Ben recommends Passionflower extract as an alternative to alcohol.
    • 18 Oct 2018 · Mung Bean · uses · YouTube ↗
      Used split yellow mung beans in his Kitchari, noting they are a fabulous source of protein and vitamins and are traditionally used as a liver cleanse.
    • 19 Jul 2018 · Mung Bean · neutral · Podcast ↗
      Mentions that a diet of mung beans and ghee can be used to enhance detoxification.
    • 19 Jul 2018 · Mung Bean · recommends · YouTube ↗
      States that the research on dal and mung beans is phenomenal for removing microbes in the gut and rebuilding beneficial gut bacteria.
    • 18 Jan 2018 · recommends · Podcast ↗
      Ben recommends Passionflower as a natural remedy for hot flashes.
    • 16 Nov 2017 · recommends · Podcast ↗
      Ben recommends Passionflower Extract as a recovery method.
    • 16 Nov 2017 · recommends · YouTube ↗
      Recommends passionflower as an inexpensive option for deep sleep.
    • 28 Jan 2017 · Mung Bean · recommends · YouTube ↗
      Recommends split yellow mung beans as they are one of the only beans with anti-flat factors, making them super easy to digest, powerfully anti-inflammatory, and anti-gas.
    • 3 Dec 2014 · recommends · Podcast ↗
      Ben recommends Passionflower for sleep.
    • 12 Mar 2014 · uses · Podcast ↗
      Includes Passionflower Extract as part of his "sleep chamber."
    • 12 Feb 2014 · recommends · Podcast ↗
      Ben recommends Passionflower for getting rid of candida.
    • 8 Jan 2014 · neutral · Podcast ↗
      Ben mentions Passionflower as part of a sleep hack stack.
    • 2 Oct 2013 · recommends · Podcast ↗
      In response to a question about natural approaches to anxiety, Ben Greenfield recommends PassionFlower extract.
  • Andrew Huberman · Passionflower · neutral
    • Date not recorded · neutral · Website ↗
      Mentions Passionflower as something that impacts the GABA system, increasing GABA and working on chloride channels to increase sleepiness and sleep.

RAL Summary

Members OnlyTier 3 for Healthy Aging

Tier 3 rests on 119 reviews, 90% of them positive, together with some support from animal studies of passionflower [1][2]. Mung bean is far below the dose that helped in its single human trial [3].

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system, Immune system, Cardiovascular system

Combine with: Combine with a healthy diet and lifestyle.

Possible side effects: No major side effects reported.

Supplement Facts

Mung Bean Extract 250 mg · Passionflower 10:1 Extract 250 mg
Supplement Facts
Serving Size 1 Capsule
Servings Per Container 120
Amount Per Serving% Daily Value
Mung Bean Extract (Vigna radiata) (seed)(10% Vitexin + 10% Isovitexin)250 mg†
Passionflower 10:1 Extract (Passiflora incarnata)(flower)250 mg†
† Daily Value not established.

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Vegetable Cellulose.

Directions: As a dietary supplement, take 1 capsule up to 2 times daily.

Barcode (UPC) 810215203024 · Label source: Reverseagelab · Report a label change

Show entire label
The Nootropics Depot Vignatex Capsules label, 120 Capsules
Vignatex Capsules, 120 Capsules

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Our articles on this subject

Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.