Pure Herbs SD-R Review
SD-R is sold by Pure Herbs under the Liquid Extracts category. The page lists the product description as (Hydrangea, Marshmallow, Stone Root) and states that it supports healthy bladder and kidney function. Two sizes are offered: a 1 oz bottle with SKU 1SDR priced at $13.75, and a 4 oz bottle with SKU 4SDR priced at $41.25, both shown as in stock. The page carries the standard disclaimer that these statements have not been evaluated by the Food and Drug Administration, and that the product is not intended to diagnose, treat, cure or prevent any disease. A warning states that the product is not intended for use by pregnant or nursing women, that anyone with a medical condition or taking medication should consult a doctor before use, and that use should be discontinued with a doctor consulted if any adverse reactions occur. The page shows no ingredients list beyond the herb names in the description, no UPC or barcode, no servings information, and no customer reviews or ratings.
Study, Trial or Testing Result Summary
Members OnlyHuman studies
No ingredient studies were provided for this product, so nothing here can be confirmed by research for immune system support. The label lists a single proprietary blend of 1887 milligrams per serving. The store listing names hydrangea, marshmallow and stone root as the herbs in that blend, but the label does not give the amount of each one. Because every herb is hidden inside the blend, there is no way to tell whether any of them is taken at a dose that has ever been studied. No human studies on immune function were found for these ingredients. The few written buyer comments that could be read describe the product as being used for kidney, bladder and gall stones rather than for immune health. These are personal stories, not clinical results, and they say nothing about colds, infections or immune strength. Until human studies on this blend or its herbs at known doses are available, any immune benefit remains unproven. Members who want immune support should know that this product is mainly marketed and used for a different purpose. Animal and cell studies are never counted.
Review Totals and Summary
Members Only5 reviews
Across the stores there are 5 ratings in total (all from Mountain Air Herbs), and the themes below come from the five written reviews that could be read on that page. That is a very small number of written reviews, so the picture is anecdotal and should be read that way. What buyers praise is almost entirely stone management. One reviewer says their husband went from having thousands of bladder stones to zero at every check-up, and calls the result amazing. Another says SD-R has made gallstones pretty much disappear, describing it as helping to soften the stones and move them through the system. This same reviewer says that during a flare they can use SD-R instead of going to the doctor or having surgery, and that it helps them keep their gallbladder. They give it five stars and would highly recommend trying it for several months before going to a surgery center. A third reviewer says the product seems to be working on kidney stones, and a fourth reports not having had a kidney stone since they started taking it earlier in the year. The fifth review simply says "Love it" without giving details. Overall the tone is strongly positive, with reviewers describing stones shrinking, softening, or not recurring, and a general satisfaction with the perceived effect. There are no real complaints in these reviews. No reviewer reports a problem, a side effect, or dissatisfaction of any kind. The closest thing to a criticism is a limitation in the reviews themselves: several are brief and do not say how long the product was used, what dose was taken, or whether a doctor confirmed the change. As for who it seems to suit, the reviewers are people dealing with bladder stones, kidney stones, or gallstones, including one person buying on behalf of a husband and one who wants to avoid surgery and keep their gallbladder. One reviewer suggests giving it several months of use before considering surgery, which hints that buyers see it as something taken over time rather than for a quick effect. Taste, form, and value are not covered. No reviewer mentions taste, price, shipping, packaging, dosage, or capsule size, so those aspects cannot be judged from these comments. I have only written about the liquid; no other forms of the product were separated out in these reviews, so nothing had to be left out on that basis, though one summary mentions capsule size only to note that nobody commented on it. These are personal experiences rather than clinical findings. The page itself states that its product statements have not been evaluated by the Food and Drug Administration, so the stone-related outcomes described here should not be taken as established medical results.
Biohacker Summary
Members Only0 of 10 recommend it
Our biohacker panel has not discussed this product’s ingredients yet.
RAL Summary
Members OnlyTier 4 for Immune Health
Tier 4 because no human studies on immune support were found for its ingredients and there are no counted reviews to judge it by. All herbs sit in a proprietary blend with undisclosed amounts.
- Emerging: not enough evidence to rank higher yet.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Urinary system, Digestive system, Immune system
Combine with: Because the ingredients of SD-R are unverified, confirm the full supplement facts before stacking. If your goal is cellular and DNA repair, consider evidence-based options such as NMN or nicotinamide riboside for NAD+ support, paired with trans-resveratrol or pterostilbene for sirtuin activation. Urolithin A supports mitochondrial renewal through mitophagy. Add antioxidants such as CoQ10 (ubiquinol), alpha-lipoic acid, and glutathione or NAC to reduce oxidative DNA damage. Magnesium, zinc, and folate or B12 support DNA synthesis and repair enzymes. Omega-3 fatty acids and vitamin D3 with K2 provide broader anti-inflammatory and cellular support. Consult a healthcare professional before combining supplements, especially with medications.
Possible side effects: No major side effects reported.
Supplement Facts
Proprietary Blend 1887 mg
| Proprietary Blend | 1,887 mg | † |
Directions: Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal. Shake well before use
Label source: NIH label database · Report a label change
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Where to Buy
Pure Herbs
We sell no supplements. Prices change; check the store.
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Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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