Pure TheraPro Rx Bio Boron 5 mg Review
Boron, a crucial trace mineral, doesn't get the attention that other more recognized minerals receive. The page says that is truly unfortunate because Boron plays a very important and under-appreciated role in supporting healthy aging. Strong, healthy bones and a properly functioning immune and inflammatory system need supplemental Boron, but the page notes this mineral can be challenging for the body to absorb. Bio Boron utilizes Albion's Bororganic Glycinate, which the page says optimizes absorption and bioavailability to ensure effective supplementation. Albion is described as the leader in high-absorption minerals. Boron is described as a biologically active trace mineral that affects calcium, magnesium, phosphorus and Vitamin D metabolism, an essential nutrient that helps maintain optimal bone metabolism and supports immune and nervous system health. The page lists several benefits. It says Boron boosts calcium, magnesium and phosphorus and activates Vitamin D, stating that the soil is depleted of Boron so supplementation may prevent the loss of these minerals, and that Boron helps convert Vitamin D into its active form to enhance calcium absorption. Bone and brain support is listed as building strong bones, supporting ligaments and tendons in the bone matrix, helping maintain cell membranes, and supporting optimal brain and cognitive function. Hormone balance is also described, with Boron said to aid the production, regulation and half-life of growth and sex hormones including testosterone and estrogen, and to protect hormones from rapid breakdown. The formula is described as zero fillers: non-GMO, soy and gluten free, and without magnesium stearate, which the page says may inhibit absorption of key nutrients. Directions say to take one capsule daily or as directed by a healthcare practitioner. If detox symptoms occur, the page advises lowering the dose to a quarter capsule and slowly increasing to the full dose. Capsules can be opened and mixed into water, juice or applesauce, consumed immediately, and not heated. The product is not for children, or for individuals who are pregnant or breastfeeding, and the page advises consulting a practitioner especially with kidney disease, impaired kidney function, or medication use. Indications listed are support for bone health, cardiovascular function and immune function. The size options shown are 5 mg with 180 capsules, 10 mg with 90 capsules, and 30 mg with 90 capsules. The page also mentions third party lab testing and a 90 day return guarantee.
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Study, Trial or Testing Result Summary
Members Only6 human studies · 4 improved
The evidence that swallowed boron helps bone health is thin. This product gives boron at a full dose, well above the 250 micrograms used in the studies. In one open study of 334 women past menopause with low bone density, a daily mineral tablet with 250 micrograms of boron plus calcium, vitamin D and other minerals raised spine bone density by about 1.5% over a year while the comparison group lost bone. Because the tablet held many ingredients and there was no placebo, the gain cannot be credited to boron [1]. In a one-year controlled trial of 28 young women, boron changed blood phosphorus and magnesium but showed no clear bone benefit [2][3]. Boric acid gel placed into gum pockets during deep cleaning improved jawbone defects compared with a placebo gel in two trials [4][5], and a review of eight gum studies agreed [6]. These gum results come from a gel applied directly to diseased gums, not from swallowed capsules, so they say little about bones elsewhere in the body. Animal and cell studies are never counted.
See all 6 studies →Hide the studies
- A review of eight studies found that adding boric acid and other medicines to gum-pocket cleaning gave better clinical and X-ray bone defect results in gum furcation defects than cleaning alone.Local drug delivery in the treatment of furcation defects in periodontitis: a systematic review.
- In 39 people with gum disease, boric acid gel placed in gum pockets alongside deep cleaning reduced X-ray bone defect depth by about 37% over 6 months versus about 3% with placebo gel.Clinical efficacy of subgingivally-delivered 0.75% boric acid gel as an adjunct to mechanotherapy in chronic periodontit…
- In 28 female college students over one year, athletes had a slight rise in bone density and sedentary students a slight fall, while boron changed blood phosphorus and magnesium and urinary boron; no clear bone benefit from boron itself was reported.Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium,…
- In 48 gum furcation defects, boric acid gel with deep cleaning gave about 17% bone fill over 6 months versus about 3% with placebo gel.Boric acid gel as local drug delivery in the treatment of class II furcation defects in chronic periodontitis: a randomi…
- In athletic and sedentary women taking boron supplements, serum phosphorus fell compared with placebo and serum magnesium rose, with modest effects on mineral status; bone density was not reported in this study.Effect of boron supplementation on blood and urinary calcium, magnesium, and phosphorus, and urinary boron in athletic a…
- In 334 postmenopausal women with osteopenia, taking the vitrum osteomag tablet (which contains 250 mcg boron per tablet) for 12 months raised bone mineral density by about 1.5% in the lumbar spine, while the control group lost bone, though the trial was open-label and not placebo-controlled.[Vitrum osteomag in prevention of osteoporosis in postmenopausal women: results of the comparative open multicenter tria…
Review Totals and Summary
Members Only222 reviews · 91% positive
Across the stores there are 114 ratings in total (111 of them on the Pure TheraPro Rx website's Okendo reviews), and the themes below come from the written reviews that could be read on that page. Those written reviews are few and mostly short, so the picture is based on only a handful of voices, even though the rating count is larger. What buyers praise: the written comments are positive, and none of the readable reviews complain about the product. Kenton gives five stars and calls it a great product, without further detail. Donna M. also gives five stars and says she is feeling better since she started taking it. A quoted testimonial on the page from Annie in Texas praises the clean formula, saying it has no junky fillers or additives. She says she is tired of other companies adding starches, stearic acid and preservatives to make capsules look full. The overall themes are strong praise for the clean, filler-free formula and for bone health results that took years to appear. Bone health results: the longest reviews come from Joann B., who posted two near-identical reviews. She was diagnosed with osteoporosis years ago and began taking Pure TheraPro Bio Boron five years earlier. At first she took a daily double dose of 60 mg, and a bone scan after one year showed no change. She then kept taking 30 mg daily, and after about five years her latest scan showed an improvement of around 20 percent in some places. Her main advice is to be patient, because bone density takes time to improve. Her reviews focus on bone density outcomes rather than on the capsules themselves, such as their size, taste or ease of swallowing. Undecided or early views: Dave M. says this is his first time trying the product and that he does not yet have enough information to give a full opinion. He plans to give it time and follow up. Complaints: no written complaints appear on the page. However, the page also shows 7 one-star ratings and 3 three-star ratings that carry no written text, so the reasons behind those lower scores cannot be known from what is readable. Who it seems to suit: based on the reviews, it appeals to people interested in bone health, especially those with osteoporosis who are willing to take it daily over a long period, and to buyers who care about supplements without fillers, starches, stearic acid or preservatives. Taste, form and value: the readable reviews say nothing about taste, capsule form or price, so no conclusions can be drawn on those points. Only the capsule product is covered here, and no reviews of other forms such as gummies or powder were identified on the page, so nothing was left out on that basis.
Biohacker Summary
Members Only6 of 10 recommend it
Boron is the main ingredient here, and the panel leans strongly in favor: of the ten, five most recently recommend it, two use it, and the rest are neutral, with nobody reporting that they stopped. The most common reasons are lowering a protein called SHBG so more testosterone is free, supporting bone formation, and helping vitamin D work, with a few also calling it a longevity mineral. Doses people give range from 2 to 12 mg a day, with 6 to 12 mg most often named for testosterone, 9 to 10 mg suggested by one for men, and one panelist saying a low dose is enough. People pair it with vitamin D, vitamin K2, magnesium and zinc, and one adds herbs for testosterone, while prunes are named as the richest food source. The one caution comes from a panelist who urges watching for side effects, though another calls it unlikely to cause harm and describes it as a safer choice for testosterone support.
See all 9 biohackers →Hide the biohackers
Siim Land · Boron · neutral
- Boron is a mineral that helps with bone density and vitamin D utilization, and also helps to increase free testosterone by reducing SHBG.
- States that boron is a superstar when it comes to hormone and bone optimization.
- Notes that prunes are the highest food source of boron.
- Prunes are an excellent source of boron, providing 1.5 to 3.0 mg of boron per 3 oz serving.
- Recommends Boron, calling it a "superhero mineral" that helps bone mineralization, improves vitamin D, improves testosterone/estrogen status, increases antioxidant defense, reduces inflammation, and reduces calcium/magnesium loss.
- Notes that Boron improves bone mineral density by improving vitamin D status and lowering inflammation, and increases testosterone and estrogen by reducing SHBG, but he stopped taking it as it didn't increase his testosterone or lower his SHBG, and it only works in particular conditions like high SHBG.
- Notes that Boron helps to lower SHBG but only to a certain degree.
- Recommends boron as a bonus to pair with a vitamin D supplement.
- Recommends boron, stating it's a mineral that helps with testosterone by lowering SHBG levels and also aids bone density, noting that many people are deficient.
- Recommends taking boron whenever taking vitamin D supplements to increase vitamin D utilization.
Dr. Eric Berg · Boron · neutral
- States that boron, along with other trace minerals, is necessary for bone formation and that K2 helps direct these minerals into the bone.
- States that Vitamin D needs K2, magnesium, zinc, B6, boron, and even vitamin A to do its job, emphasizing that vitamins rarely work alone.
- Recommends getting plenty of boron when taking vitamin D.
- Mentions that boron is a crucial nutrient needed for vitamin D to go through its biochemical reactions and maximize its effectiveness.
- Recommends taking boron as a cofactor when taking vitamin D to help shrink fibroids, suggesting the recommended dose on the bottle.
- Recommends ensuring adequate boron intake when taking vitamin D supplements.
- States that boron may help prevent calcification of the soft tissues.
- Recommends starting with 3 mg of boron three times per day to help relieve arthritis symptoms, noting that it helps keep minerals inside the bone, allows vitamin D to be activated, and helps prevent tooth decay.
- Includes Boron as a natural alternative to increase vitamin D levels and combat vitamin D resistance.
- States that boron helps override the problem of vitamin D receptor resistance.
Ben Greenfield · Boron · recommends
- Recommends using hormone building blocks like boron for hormone optimization.
- Recommends consuming boron as a building block for testosterone.
- Recommends boron as one of the foundational supplements to consider before TRT for testosterone support.
- Recommends boron as an important precursor for testosterone.
- States that boron is important for naturally increasing testosterone.
- Recommends checking boron levels and ensuring adequate intake if testosterone is low.
- Uses Boron, which he knows anecdotally helps with testosterone, but his cardiologist recommended it for heart health.
- Warns of boron deficiency on a strict carnivore diet, as it is not found in many meats or organ meats, and low intake has been linked to issues with bone health, brain health, and hormone production.
- Recommends ensuring adequate boron intake as a foundational element before considering testosterone therapy for issues like poor libido or decreased performance.
- States he gets boron from bone broth.
Dave Asprey · Boron · neutral
- Lists boron as one of the minerals needed.
- Mentions using boron.
Bryan Johnson · Boron · uses
- Takes 2 mg of Boron in the morning for longevity.
- Takes 6 mg of Boron in the morning.
- Takes 6 mg of Boron in the morning for longevity.
- Recommends boron as a mineral that, along with calcium, phosphorus, and magnesium, is deposited to fortify the bone structure.
- Mentions boron as a potential therapy that could positively influence sperm health.
Dr. Rhonda Patrick · Boron · recommends
- Recommends Boron, stating it potentially reduces SHBG levels, freeing up bound testosterone, and is particularly useful at dosages around 6-12 mg daily.
- Boron may play a supportive role for optimizing testosterone. Supplementing with 6-12 mg per day can increase free testosterone by suppressing SHBG.
- Supplementing with boron may boost free testosterone by lowering sex hormone-binding globulin (SHBG). While boron won’t increase total testosterone production, doses around 6 to 12 mg daily may help free up more testosterone by modestly reducing SHBG levels.
- Suggests Boron as a safer choice for boosting testosterone due to its safety profile, and notes that it has also been thought to potentially be a longevity molecule.
- Takes a low dose of boron.
- She occasionally uses boron, meaning about twice a week.
Dr. Mark Hyman · Boron · recommends
- Recommends taking Boron if you have high sex hormone binding globulin (SHBG) to lower it and increase free testosterone.
- Mentions that sometimes antifungal medications like boronox are needed for fungal overgrowth.
- Lists boron as a critical nutrient for building strong bones.
- Mentions that boron is needed for bone formation.
- States that most people will still be lacking boron because it is very difficult to source in the diet, making it a great supplement to take.
- Mentions there is some evidence that boron can be helpful for osteoporosis.
- Lists Boron Glycinate: 2 mg by Pure Encapsulations as a product available.
Thomas DeLauer · Boron · recommends
- Recommends boron for helping with sex hormone binding globulin decreases, leading to more free androgens and potentially balancing estrogen.
- Uses a mix of magnesium, zinc, and boron, along with Tongkat Ali and Forskolii, to support testosterone levels and increase libido, especially during prolonged deficits.
- Recommends that men try supplementing with 9 milligrams of boron to help release testosterone in the form of free testosterone by unbinding it from sex hormone-binding globulin.
- Recommends that males experiment with taking boron, possibly 9 milligrams, as it has been shown to unbind testosterone from sex hormone binding globulin, helping to balance estrogen and androgen levels.
- Recommends boron, stating it doesn't increase total testosterone but unlocks bound testosterone to be free, with studies showing a significant increase in available free testosterone after one week of 10 milligrams daily.
- Recommends boron for males to unlock bound-up testosterone, leading to more muscle mass, energy, strength, and libido.
- Recommends consuming small amounts of boron, specifically six to nine milligrams a day, as studies have shown it can increase free testosterone levels.
- Recommends boron, noting that it helps the kidneys retain magnesium and sustains the half-life of vitamin D, which prevents fluctuations that can be hard on the body and helps avoid vitamin D deficiency.
- Recommends taking between 6 and 15 milligrams of boron daily to get the most impact, as studies show it increases free testosterone and decreases sex hormone binding globulin.
Andrew Huberman · Boron · recommends
- Recommends boron, at a dose of 5 to 12 milligrams per day, to acutely help lower high SHBG, noting that it's depleted in soils in many countries.
- Explains that boron, an element found in rich soils, can help regulate SHBG, and is unlikely to have a bad effect, suggesting a dose of 3 to 6 milligrams once to twice a day.
- Discusses boron in relation to nettles, the prostate, and the blood brain barrier.
- Notes that there is scientific support for boron freeing up more testosterone, with people typically taking a couple grams a day, and encourages examining potential side effects.
- Andrew Huberman has long been taking boron, at two to four milligrams per day, as part of a cocktail for testosterone augmentation.
- Andrew Huberman recommends boron in a dose of 5 to 12 milligrams per day to acutely help lower very high SHBG, though it's not a sustained effect.
RAL Summary
Members OnlyTier 4 for Bone Health
The tier rests on two trials of boric acid gel placed into gum pockets during dental cleaning, which is a local gum treatment and not a swallowed boron supplement, while the oral studies show no clear bone benefit that can be credited to boron. So it is graded Tier 4, lower than the rules alone gave.
- Emerging: not enough evidence to rank higher yet.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Skeletal system
Combine with: For bone health, pair boron with vitamin D3 (2,000-5,000 IU), vitamin K2 (MK-7, 100-200 mcg) to direct calcium into bone, magnesium glycinate or citrate, and a well-absorbed calcium source such as calcium citrate or microcrystalline hydroxyapatite if dietary intake is low. Collagen peptides and silica may add structural support. If the real goal is cellular and DNA repair, add a separate product containing NMN or NR, quercetin, resveratrol or pterostilbene, alpha-lipoic acid, and glutathione or NAC, and consult a healthcare provider before combining, especially with medications.
Possible side effects: No major side effects reported.
Supplement Facts
Boron 5 mg
| Boron | 5 mg | † |
Other ingredients: Hypromellose, Glycine.
Directions: Directions: Take one (1) capsule one to two times daily, or as directed by a healthcare practitioner.
Label source: NIH label database · Report a label change
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Graded November 10, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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