Solgar Whole and Complete Pomegranate Review
Tier ⓘ
Tier 2 · Rank 37
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 37 within Tier 2 for Healthy Aging; 51 of 196 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
67 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
91% of 2,414
Biohacker Mentions
0 of 10
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Study, Trial or Testing Result Summary
Members Only46 human studies · 29 improved
46 human studies29 improved9 no effect5,813 people studied
This product gives 800 milligrams of whole fruit pomegranate extract a day, above the 500 milligrams that worked in studies. No human study has shown that pomegranate turns back biological age, and a 12 week trial in adults aged 55 to 70 found no change in telomere length, though a growth-related blood factor rose [1]. The stronger evidence is for inflammation and oxidative stress, which are markers tied to aging. A pooled analysis of 33 randomized trials found pomegranate lowered several inflammation markers and a marker of oxidative damage, and raised antioxidant capacity [2]. A pooled analysis of 21 trials found similar antioxidant gains [3]. In adults aged 55 to 70, 740 milligrams of extract daily for 12 weeks lowered inflammation markers and systolic blood pressure compared with placebo [4]. Results were not uniform. A pooled analysis of 11 trials with 484 people found no significant change in antioxidant or oxidative damage markers [5], and another pooled analysis found mixed results and judged the evidence low quality [6]. Animal and cell studies are never counted.
See all 46 studies →Hide the studies
- In 47 trials of 3852 people with rheumatoid arthritis, dietary polyphenols (pomegranate extract in only one trial) improved disease activity, inflammation and oxidative stress without more side effects.Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomiz…
- Across 11 randomized trials with 484 people, pomegranate did not significantly change antioxidant capacity, glutathione peroxidase, paraoxonase or malondialdehyde (a marker of oxidative damage).The effect of pomegranate on oxidative stress parameters: A systematic review and meta-analysis.
- In 21 randomized trials, pomegranate raised total antioxidant capacity and superoxide dismutase and lowered malondialdehyde compared with controls, with no significant change in several other antioxidant markers.Does pomegranate consumption improve oxidative stress? A systematic review and meta-analysis of randomized controlled cl…
- Pooling randomized trials with follow-up from 3 weeks to 12 months, pomegranate significantly raised glutathione peroxidase and total antioxidant capacity and lowered TBARS, but did not significantly change malondialdehyde, oxidized LDL or paraoxonase 1, and the evidence was low quality.Is Consumption of Pomegranate Supplementation Effective on Oxidative Stress Biomarkers Including MDA, ox-LDL, POX 1, GPX…
- Across 33 randomized trials in adults, pomegranate lowered C-reactive protein, interleukin-6, tumor necrosis factor alpha and malondialdehyde, and raised total antioxidant capacity.The effects of pomegranate consumption on inflammatory and oxidative stress biomarkers in adults: a systematic review an…
- In a review of 11 poor-quality trials of plant extracts for skin aging, a blend containing pomegranate extract did not significantly reduce wrinkles.Botanical extracts as anti-aging preparations for the skin: a systematic review.
- A review of studies in healthy adults found pomegranate may lower oxidative stress and inflammation and improve endurance, strength and recovery after exercise, but benefits were less likely with low-polyphenol products or short time between intake and testing.Effects of pomegranate supplementation on exercise performance and post-exercise recovery in healthy adults: a systemati…
- A review of twelve human, animal and lab studies found pomegranate reduced inflammation and oxidative stress and eased symptoms in rheumatoid arthritis, with no serious unfavourable effects reported.Potential effects of pomegranate (Punica granatum) on rheumatoid arthritis: A systematic review.
- In seven trials of hemodialysis patients lasting from one session to one year, pomegranate may have lowered blood pressure, oxidative stress and inflammation and improved blood fats, though few studies were available.The effect of pomegranate consumption on cardiovascular risk factors in hemodialysis patients: A systematic review of cl…
- In 120 men aged 36-55, 56 days of a pomegranate rind and cocoa seed extract blend (200 or 400 mg) reduced aging male symptom scores, raised testosterone, and improved hand-grip strength and perceived stress compared with placebo.A proprietary blend of standardized Punica granatum fruit rind and Theobroma cocoa seed extracts mitigates aging males' …
- In 114 people with type 2 diabetes, 3 months of a pomegranate, green tea and vitamin C supplement lowered a lipid damage marker and raised antioxidant defenses more than placebo.The effects of polyphenol-containing antioxidants on oxidative stress and lipid peroxidation in Type 2 diabetes mellitus…
- In 101 hemodialysis patients, one year of pomegranate juice (100 ml three times weekly) reduced oxidative stress, inflammation and infection-related hospitalizations versus placebo, and 25% had improved artery disease; benefits faded 3 months after stopping.One year of pomegranate juice intake decreases oxidative stress, inflammation, and incidence of infections in hemodialys…
- In 90 postmenopausal women, 8 weeks of a polyphenol mixture raised total cholesterol, LDL cholesterol and triglycerides compared with placebo, while lowering oxidised LDL and improving LDL quality.Polyphenols increase circulating lipids but improve LDL particle quality and reduce LDL oxidation in postmenopausal wome…
- Adults aged 55 to 70 taking 740 mg of pomegranate extract daily for 12 weeks had significant drops in the inflammatory markers IL-6 and IL-1 beta and in systolic blood pressure compared with placebo.Effects of Pomegranate Extract on Inflammatory Markers and Cardiometabolic Risk Factors in Adults Aged 55-70 Years: A Ra…
- In adults aged 55 to 70, 740 mg of pomegranate extract daily for 12 weeks raised blood levels of the growth hormone-related factor IGF-1 compared with placebo, but did not change telomere length.Effects of Pomegranate Extract on IGF-1 Levels and Telomere Length in Older Adults (55-70 Years): Findings from a Random…
- In 70 men with prostate cancer, POMx pomegranate extract tablets taken for up to 4 weeks before surgery did not significantly lower prostate tissue oxidative damage compared with placebo, though urolithin A built up in prostate tissue.A double-blind, randomized, neoadjuvant study of the tissue effects of POMx pills in men with prostate cancer before rad…
- In 60 adults with type 2 diabetes, drinking 200 ml of pomegranate juice daily for 6 weeks lowered oxidised LDL and raised total antioxidant capacity compared with the control group.Effects of pomegranate juice consumption on oxidative stress in patients with type 2 diabetes: a single-blind, randomize…
- In adults with type 2 diabetes, 250 mg of pomegranate peel extract twice daily for eight weeks lowered inflammation and oxidative stress blood markers and raised total antioxidant capacity compared with placebo.A prospective, randomized, double-blind, placebo-controlled trial of polyphenols on the outcomes of inflammatory factors…
- Taking a daily combination of 10 supplements, including 250 mg of pomegranate extract, for 24 weeks did not change arterial stiffness, blood vessel function, inflammation, oxidative stress or cardiometabolic risk factors in non-obese adults aged 38 to 55.Multiple dietary supplements do not affect metabolic and cardio-vascular health.
- In 55 adults with rheumatoid arthritis, 500 mg per day of pomegranate extract for 8 weeks reduced disease activity more than a placebo capsule and raised a blood antioxidant enzyme, but did not change CRP or MMP3.Pomegranate extract alleviates disease activity and some blood biomarkers of inflammation and oxidative stress in Rheuma…
- In a placebo-controlled trial of 48 overweight or obese adults, 1000 mg of pomegranate extract daily for 30 days lowered malondialdehyde, interleukin-6, and C-reactive protein, along with glucose, insulin and LDL cholesterol, compared with placebo.Effects of pomegranate extract supplementation on inflammation in overweight and obese individuals: A randomized control…
- In 44 overweight or obese women with polycystic ovary syndrome, 45 ml a day of concentrated pomegranate juice for 8 weeks lowered testosterone compared with no intervention, but did not change inflammation or oxidative stress markers after adjustment.The effect of concentrated pomegranate juice on biomarkers of inflammation, oxidative stress, and sex hormones in overwe…
- Hemodialysis patients drinking 100 ml of pomegranate juice after each session for 8 weeks had lower blood pressure, lower triglycerides, higher good cholesterol, higher antioxidant capacity, and lower malondialdehyde and IL-6 than during usual care.Pomegranate juice improves cardiometabolic risk factors, biomarkers of oxidative stress and inflammation in hemodialysis…
- In a double-blind trial of 40 people, drinking 50 ml of fermented pomegranate extract daily for 8 weeks improved skin moisture, brightness, elasticity and collagen density compared with baseline.Fermented pomegranate extracts protect against oxidative stress and aging of skin.
- In healthy adults aged 60 to 75, four weeks of a citrus and pomegranate supplement improved handgrip strength, thinking and memory scores, and a blood marker of oxidative stress compared with placebo, but did not change fitness tests or other measures.The Effect of a Citrus and Pomegranate Complex on Physical Fitness and Mental Well-Being in Healthy Elderly: A Randomize…
- In 35 healthy adults, 250 g of pomegranate juice daily for 3 weeks raised plasma antioxidant activity and lowered urinary markers of oxidative damage.Three week dietary intervention using apricots, pomegranate juice or/and fermented sour sobya and impact on biomarkers o…
- In adults on dialysis, 1000 mg of pomegranate extract daily for six months raised an antioxidant enzyme's activity and lowered blood pressure at first, but the blood pressure change did not hold after adjusting for baseline, and muscle strength and physical function did not change compared with placebo.Effects of Pomegranate Extract Supplementation on Cardiovascular Risk Factors and Physical Function in Hemodialysis Pati…
- In 31 endurance athletes, 200 ml of pomegranate juice daily for 21 days kept or lowered oxidative damage markers, while the control group's markers rose.Effects of pomegranate juice in circulating parameters, cytokines, and oxidative stress markers in endurance-based athle…
- Drinking 400 ml of pomegranate juice daily for 5 weeks did not change oxidative stress, blood markers, or breathing function compared with placebo in people with stable COPD.Pomegranate juice supplementation in chronic obstructive pulmonary disease: a 5-week randomized, double-blind, placebo-c…
- In men with low-risk prostate cancer on active surveillance, 1000 mg of pomegranate fruit extract daily for one year lowered a DNA damage marker in prostate tissue compared with baseline, but did not change blood IGF-1 or prostate-specific antigen levels compared with placebo.A phase II randomized placebo-controlled trial of pomegranate fruit extract in men with localized prostate cancer underg…
- In 27 hemodialysis patients randomized to pomegranate juice or placebo, a single dose of juice prevented the rise in oxidative stress and inflammation markers caused by intravenous iron during one dialysis session.Pomegranate juice intake attenuates the increase in oxidative stress induced by intravenous iron during hemodialysis.
- Dialysis patients taking 1,050 mg of pomegranate extract daily for 4 weeks had no change in inflammation, oxidative stress, or blood pressure, though both juice and extract were found safe and well tolerated.A pilot randomized crossover trial assessing the safety and short-term effects of pomegranate supplementation in hemodia…
- In 24 overweight adults with high cholesterol, drinking 300 mL of pomegranate juice daily for 2 weeks lowered diastolic blood pressure, bad cholesterol, and liver enzymes and raised an antioxidant enzyme's activity compared with controls, but it also reduced one omega-3 fat in the blood.Short-Term Consumption of Pomegranate Juice Alleviates Some Metabolic Disturbances in Overweight Patients with Dyslipide…
- In 24 healthy adults, a 300 mg blend containing pomegranate for 9 days improved muscle pain tolerance and sleep quality after hard exercise, but did not change inflammation, oxidative stress or muscle damage markers.The Effects of a Phytochemical Supplement Blend on Markers of Exercise-Induced Muscle Damage: A Randomised Controlled Tr…
- In 23 a med-treated adults with high cholesterol, 1 g per day of pomegranate extract for 2 months lowered reactive oxygen species in immune cells and improved blood lipid and antioxidant status compared with placebo.Read the study on PubMed (24401239) →
- Pregnant women who drank about 8 ounces of pomegranate juice daily until delivery had lower oxidative stress in their placentas than women given apple juice, and pomegranate juice also reduced cell damage in placental cells grown in the lab.Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trop…
- In a triple-blind trial of women with polycystic ovary syndrome, 300 mL of pomegranate juice daily for 8 weeks lowered malondialdehyde and raised total antioxidant capacity compared with placebo, and lowered a inflammation marker in the juice-only group.The effect of synbiotics pomegranate juice on cardiovascular risk factors in PCOS patients: a randomized, triple-blinded…
- In patients on methadone or buprenorphine for a med addiction, 250 ml of pomegranate juice daily for 120 days improved drug craving and raised blood antioxidant capacity.Read the study on PubMed (39798867) →
- A single 10 gram dose of grape and pomegranate pomace supplement did not improve glucose or insulin responses or antioxidant capacity in adults with abdominal obesity.Effects of acute intake of grape/pomegranate pomace dietary supplement on glucose metabolism and oxidative stress in adu…
- In 10 patients with carotid artery narrowing, one year of pomegranate juice reduced artery wall thickness, systolic blood pressure and LDL oxidation compared with a non-drinking control group, with the largest effects at one year.Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media t…
- In 10 adults with type 2 diabetes, 50 ml of pomegranate juice daily for three months lowered blood lipid peroxides and TBARS, raised a protective enzyme's activity and reduced oxidized cholesterol uptake in immune cells, compared with healthy controls who did not take juice.Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages.
- In 9 elite weightlifters, pomegranate juice before training reduced the rise in a blood marker of cell damage (malondialdehyde) compared with placebo and boosted antioxidant responses for up to 48 hours.Effects of Pomegranate Juice Supplementation on Oxidative Stress Biomarkers Following Weightlifting Exercise.
- In 14 healthy volunteers, daily pomegranate juice for 15 days raised blood glutathione and lowered lipid and protein oxidation, with some benefit still present a week after stopping.Pomegranate juice consumption increases GSH levels and reduces lipid and protein oxidation in human blood.
- In a small open-label pilot, patients with active rheumatoid arthritis drinking 10 ml of pomegranate extract daily for 12 weeks had lower disease activity scores and lower serum oxidative stress.Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumat…
- In a single-group study of men with rising PSA after prostate cancer treatment, daily pomegranate juice lengthened PSA doubling time from about 15 to 54 months and reduced blood markers of oxidative stress, with no serious side effects.Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for pro…
- Biscuits made with pomegranate peel powder were tested in cell cultures and by a 30-person taste panel; no human health outcome was measured, so no anti-aging benefit was shown.Recovery from Food Waste-Biscuit Doughs Enriched with Pomegranate Peel Powder as a Model of Fortified Aliment.
Review Totals and Summary
Members Only2,414 reviews · 91% positive
2,414 reviews · Amazon 2,414
91% positive6% neutral3% negative
Extensive customer reviews and qualitative feedback are currently being aggregated for this product. Check back soon for a detailed sentiment analysis.
Biohacker Summary
Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it
The panel is split on pomegranate, the main ingredient: two of the ten statements below lean toward using it, one recommends it outright, one stopped, and four stay neutral on it. Those who like it take it for heart health, blood pressure, nitric oxide, gut bacteria and as a source of urolithin A, and they favor whole seeds or pearls, with some using small amounts of juice (one tablespoon, or 60 mL stirred into a pudding) and one suggesting bitter powdered peel in capsules. Several say eating pomegranate gives uneven urolithin A because only some people have the gut bacteria to make it, and two note you would need a huge pile of fruit or about 60 pomegranates to match a direct supplement. One panelist stopped eating it after getting sore joints from the oxalates and sugar in the seeds, and others flag the sugar in juice. One mentions daily consistency to build up the right gut bacteria, and fiber from whole seeds is said to help that.
See all 8 biohackers →Hide the biohackers
Thomas DeLauer · Pomegranate · neutral
- Explains that Urolithin A is derived from pomegranates, but eating pomegranates does not provide the same absorption of Urolithin A as a pure supplement.
- Recommends consistently eating whole pomegranate pearls, rather than just the juice, because the fiber feeds the gut bacteria necessary for Urolithin A conversion, gradually shifting the microbiome towards greater production.
- Recommends consuming pomegranates consistently, even daily, to develop the gut bacteria, specifically Akkermansia, that can extract Urolithin A from them.
- Recommends pomegranate for lung health, noting that ellagitannins provide airway antioxidant defense.
- Recommends pomegranates to support specific bacteria that produce butyrate.
- Rates pomegranate arils as a 9.5, mentioning that punicalagins are converted into urolithin A by the gut, providing a super cool overall benefit.
- Notes that Urolithin A is normally produced in the gut when bacteria metabolize polyphenols from specific foods like pomegranate, but over 60% of people cannot efficiently convert pomegranate into Urolithin A.
- Recommends pomegranates for the lungs, stating that ellagitannins help protect against particles.
- Recommends pomegranates for gut barrier integrity, noting that their polyphenols interact with signaling pathways to support intestinal integrity, and even small, consistent exposure, like a tablespoon a week, can be beneficial.
- Recommends pomegranate extract as a source of Urolithin A, which signals for autophagy, but notes that conversion to usable Urolithin A might not always occur.
Ben Greenfield · Pomegranate · neutral
- Questions the efficacy of pomegranate extract for plaque melting, asking how an enzyme can get through stomach acid and if the gut bacteria can utilize its chemical trash to make K.
- Mentions pomegranates as a food that increases angiogenesis, as outlined in Dr. William Lee's book 'Eat to Beat Disease'.
- Notes that 1,000 mg of urolithin A is equivalent to juicing 60 pomegranates, which would also result in a lot of sugar.
- Mentions that daily pomegranate juice has been shown in clinical research to slow arterial plaque progression and support healthy blood pressure.
- Revisits the powerful heart-protective hack of adding pomegranate juice to one's routine to help reduce arterial plaque and lower blood pressure.
- Recommends consuming 50 ml of pomegranate juice daily for plaque reduction, lower blood pressure, and reduced LDL oxidation, citing studies showing it can reverse plaque accumulation and improve antioxidant status.
- Mentions that pomegranate was known as the royal fruit of the Bible and that the average pomegranate contains 613 seeds, the same number of commandments in the Old Testament.
- Mentions that juicing 30 pomegranates would provide 500 milligrams of Urolithin A, highlighting the impracticality of getting sufficient amounts from food alone due to the high sugar content and effort involved.
- Recommends pomegranate juice as a nitrate-rich food that converts into nitric oxide.
- Mentions pomegranates as a sirtuin that might contribute to anti-aging by upregulating the body's own reactive oxygen species defense mechanisms.
Dave Asprey · Pomegranate · stopped
- Would have to eat a ridiculous pile of pomegranates every day to get enough Urolithin A, and they are not doing that.
- Notes that pomegranates contain compounds that gut bacteria convert into urolithin A, which activates mitophagy through a unique biological pathway.
- Dave notes that eating pomegranates or taking cheap pomegranate extract does not work for most people to produce urolithin A.
- Dave Asprey used to eat pomegranates from his backyard tree but would get sore joints because pomegranate seeds have a lot of oxalates and sugar.
- Discusses the massive problem with trying to get Urolithin A from pomegranates, as only 30% of people have the right gut bacteria to even make it.
- Mentions that one would need six cups of pomegranate juice a day to hit the minimum effective dose of Urolithin A.
- Notes that pomegranates have been used by Persian and Greek doctors for thousands of years to improve vitality, and modern science is finally catching up to why.
- Notes that pomegranates have been associated with longevity and ancient doctors used them to improve vitality, but only about 30% of people can produce urolithin A from them.
- Mentions that pomegranate juice is another substance that can reverse plaque.
- Warns that drinking pomegranate juice to get enough urolithin A is not effective due to the high sugar content and the fact that 60-70% of people lack the necessary gut bacteria to convert it.
Dr. Eric Berg · Pomegranate · recommends
- Recommends pomegranate seeds as a top food to help increase nitric oxide.
- Recommends consuming pomegranate seeds to increase nitric oxide.
- Recommends pomegranate seeds as a potent heart healer, especially for decreasing the risk of plaque, supercharging nitric oxide, and helping to reduce blood pressure.
- Recommends pomegranates as they are rich in ellagic acid, known for its anticancer properties, protecting DNA from damage and decreasing inflammation and oxidative stress.
- Recommends consuming pomegranate for its polyphenols to help detoxify aldehydes.
- Recommends pomegranate for its compound that reduces inflammation, helps mitochondria, and inhibits the spread of cancer.
- Recommends pomegranate for decreasing inflammation and preventing fat from accumulating in the liver.
- Recommends pomegranates for their ellagic acid, which has anti-cancer properties, protects DNA from damage, and decreases inflammation and oxidative stress.
- Recommends pomegranate seeds, noting they are loaded with phytonutrients, including one that helps support collagen, and expresses a personal liking for them.
- Recommends pomegranate, noting that its phytochemicals can mimic the body's estrogen in a positive way and help balance estrogen by blocking bad estrogen.
Dr. Rhonda Patrick · Pomegranate · neutral
- Explains that pomegranate contains polyphenols called ellagitannins, which gut bacteria convert into Urolithin A, but there's significant individual variation in how much Urolithin A people actually produce from eating it.
- Some people produce urolithin A after eating pomegranates and walnuts, but others need to supplement directly.
- Recommends eating pomegranate, especially the arils and the bitter pith, as it is the best source of ellagitannins, which are precursors to urolithin A, and the food matrix improves bioavailability and increases beneficial gut bacteria.
- Dr. Rhonda Patrick notes that pomegranates are foods rich in ellagitannins, which gut microbes can convert into urolithin A.
Bryan Johnson · Pomegranate · uses
- Uses pomegranate juice as an ingredient in Nutty Pudding.
- Uses pomegranate seeds because they have unique polyphenols that protect cholesterol from oxidation, which improves blood flow.
- Finishes his Nutty Pudding with 60 mL of pomegranate juice for antioxidants and heart health.
- Includes pomegranate juice in his Nutty Pudding, which he consumes an hour after his Super Veggie.
- Has pomegranate seeds in his fridge.
- Includes pomegranate juice in his 'Nutty Pudding' as part of his fat profile for the third meal of the day.
- Bryan Johnson uses 60 ml of pomegranate juice in his Nutty Pudding.
Dr. Mark Hyman · Pomegranate · neutral
- Mentions that pomegranate juice has been known for a long time to be healthy and confer health benefits, but the mechanism was not clear until ellagitannins and their metabolism into urolithin A by the microbiome were discovered.
- Mentions that pomegranate has super beneficial effects on Akkermansia muciniphila, a keystone species that protects the gut lining, prevents leaky gut, reduces inflammation, and helps metabolic health.
- Uses pomegranates, specifically 1 tbsp of 100% pomegranate juice, for their polyphenols and beneficial phytonutrients without spiking blood sugar, to feed Akkermansia muciniphila.
- Was given pomegranate as part of a program to rehab his gut and rebuild bacteria.
- Dr. Hyman notes that pomegranates are a food containing polyphenols that the gut microbiome can convert into Urolithin A.
- States he took pomegranate in high doses every day in concentrates to regrow his Akkermansia when he had colitis.
- Recommends pomegranate powder as a prebiotic to feed probiotics and help rebalance the microbiome.
- Dr. Hyman explains that if one's gut microbiome can metabolize pomegranate ellagitannins, it produces Urolithin A, which has beneficial effects on rejuvenating and cleaning up mitochondria.
- Recommends pomegranate as an awesome food that helps blood flow and circulation.
- Mentions that his mother was given pomegranate juice and other foods to help grow good bacteria, which contributed to the successful elimination of her cancer through immunotherapy.
Siim Land · Pomegranate · uses
- Pomegranate seeds are one of Siim Land's go-to fruits.
- Loves pomegranates because they are loaded with urolithin, which she tries to get in food form for longevity.
- Lists pomegranate as a food that contains nitrates and helps with nitric oxide production.
- Mentions pomegranate as an example of a food containing dark phenols that helps glucose function.
- Recommends powdered pomegranate peels, rich in ellagic acid and ellagitannins, which convert to urolithin A by the microbiome, for profound benefits and autophagy activation, noting they are very bitter and should be capsuled.
RAL Summary
Members OnlyTier 2 for Healthy Aging
Most human trials, including a pooled analysis of 33 randomized trials and a trial in older adults, show improvements in inflammation and oxidative stress markers, and 91% of 2414 reviews are positive. There is no evidence that it reverses biological age.
Where the evidence disagrees: 9 of the 46 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Immune system, Cardiovascular system
Combine with: Combine with a healthy diet and lifestyle.
Possible side effects: No major side effects reported.
Supplement Facts
Total Carbohydrates 1 g · standardized Pomegranate whole fruit extract 800 mg
Supplement Facts
Serving Size 2 Vegetarian Capsule(s)
Servings Per Container 30
Amount Per Serving% Daily Value
| Total Carbohydrates | 1 g | |
| standardized Pomegranate whole fruit extract | 800 mg | † |
† Daily Value not established.
Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silica.
Directions: Suggested Use: As a dietary supplement for adults, take two (2) vegetable capsules daily, preferably at mealtime, or as directed by a healthcare practitioner.
Barcode (UPC) 033984022447 · Label source: NIH label database · Report a label change
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Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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