Spring Valley Echinacea & Goldenseal Extract Blend Review
This Spring Valley Echinacea Goldenseal Blend 900 mg Dietary Supplement is presented as a dietary supplement for immune health. The key features list states that each serving provides a 900 mg equivalent of an echinacea and goldenseal blend. The product comes as 75 vegetarian capsules in a single-count option, and the page also lists a 225 count option at a higher total price of $15.15. The listed features state that the product has no preservatives, no artificial color, and no artificial flavor. It is listed as kosher and Non-GMO Project Verified. The page states the product contains no gluten, yeast, wheat, milk or milk derivatives, lactose, or soy. The feature list also includes a United States coin image from the United States Mint, which the page does not explain further. The full item details, specifications, indications, directions, ingredients and warnings sections are not expanded in the scraped text, so no further claims are made here. The listing is sold on Walmart under the Spring Valley brand, and the page shows an overall rating of 4.8 out of 5 from 932 ratings, with no star breakdown or written reviews visible in the scraped text.
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Study, Trial or Testing Result Summary
Members Only44 human studies · 28 improved
This product holds echinacea and goldenseal in a blend, and the label does not say how much of each herb is inside, so it is unclear whether the echinacea matches studied amounts. None of the studies given tested goldenseal. For echinacea, the results are mixed. A 2025 review of 9 trials in 3169 children found echinacea shortened and reduced upper respiratory infections and cut a med use, though mild side effects were more common [1]. An earlier review of 24 trials in 4631 people found echinacea was not shown to prevent or shorten colds, though a weak benefit was possible [2]. In a trial of 80 adults, 200 milligrams of echinacea daily for 8 weeks raised natural killer cell activity and some immune signals but did not change cold symptoms or fatigue [3]. Several controlled trials found no benefit for preventing or treating colds. Other positive studies in the evidence tested Chinese herbal formulas for chest infections, pneumonia and hepatitis B, not this echinacea and goldenseal blend, so they do not apply to this product [4][5][6]. Animal and cell studies are never counted.
See all 44 studies →Hide the studies
- Across 24 double-blind trials with 4631 people, Echinacea products were not shown to prevent or shorten colds, though a weak benefit was possible.Echinacea for preventing and treating the common cold.
- In 21 trials with 3425 children with lower respiratory infections, adding Xiaoer-Feike granules to usual medicine raised the clinical response rate, shortened cough, fever and hospital stay, and improved immune and inflammation blood markers.Meta-Analysis on the Chinese Herbal Formula Xiaoer-Feike Granules as a Complementary Therapy for Children With Acute Low…
- In 9 trials with 3169 children, Echinacea purpurea reduced upper respiratory infection duration, incidence and a med use, but mild side effects were more common.Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis media in …
- In 38 studies with 2890 patients with drug-resistant pneumonia, adding Chinese herbal compounds to meds improved response rate, bacterial clearance and inflammation markers and shortened hospital stay.Chinese herbal compound for multidrug-resistant or extensively drug-resistant bacterial pneumonia: a meta-analysis and t…
- In 31 trials with 2496 lung cancer patients, adding modified Yukgunja-tang to standard therapy improved tumor response, performance status and immune cell markers, and reduced treatment side effects.Therapeutic potential of modified Yukgunja-tang (Liujunzi Decoction, Rikkunshito) as an adjuvant treatment for lung canc…
- In 16 trials, Echinacea did not prevent colds, and treatment results were mixed, with some evidence that aerial parts of Echinacea purpurea may help early cold treatment in adults.Echinacea for preventing and treating the common cold.
- A review of 45 reports on herbal products for children's respiratory infections found the strongest evidence for Pelargonium root extract EPs 7630, while evidence for other products was limited.Phytotherapy for acute respiratory tract infections in children: a systematically conducted, comprehensive review.
- In 740 elderly people in Hong Kong given a herbal formula or placebo for 8 weeks, flu-like illness was not reduced, though natural killer cell counts were higher in the herbal group.A herbal formula for prevention of influenza-like syndrome: a double-blind randomized clinical trial.
- In 407 children aged 2 to 11 given echinacea or placebo for up to 3 colds over 4 months, echinacea did not shorten or ease cold symptoms and was linked to more rashes.Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled tri…
- In 395 adults with chronic hepatitis B given a Chinese herbal formula or placebo for 96 weeks, more people in the herbal group had lower virus levels (18.6% vs 2.6%) and cleared the e antigen (16.1% vs 5.6%).Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients.
- In 302 healthy volunteers taking echinacea root extract or placebo for 12 weeks, the time to a first respiratory infection did not differ significantly between groups.Echinacea root extracts for the prevention of upper respiratory tract infections: a double-blind, placebo-controlled ran…
- In 282 adults taking a standardized echinacea liquid or placebo at the start of a cold for 7 days, daily symptom scores were 23.1% lower with echinacea among those who followed the protocol.Efficacy of a standardized echinacea preparation (Echinilin) for the treatment of the common cold: a randomized, double-…
- In adults who caught a common cold, Echinaforce taken three times daily until they felt well again (no more than 7 days) reduced cold symptom scores more than placebo, and was well tolerated.Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized, placebo cont…
- In 201 children aged 4 to 12 given echinacea tablets three times daily for two 2-month periods, there were fewer cold days and fewer a med courses than in children given vitamin C (control).Read the study on PubMed (33832544) →
- In 177 adults with acute cold, 30 ml per day of a combination herbal solution containing 762 mg of extracts for 5 days relieved cough more effectively than placebo.Antitussive effect of a fixed combination of Justicia adhatoda, Echinacea purpurea and Eleutherococcus senticosus extrac…
- In 153 women with mild cervical lesions, an Echinacea supplement taken for three months led to more lesion clearance at 6 and 12 months than the comparison groups, with 46 of 51 women in the combined-treatment group clear at 12 months.Echinacea angustifolia and Echinacea purpurea Supplementation Combined with Vaginal Hyaluronic Acid to Boost the Remissi…
- In 148 college students with a new common cold, taking echinacea capsules (1 gram doses, up to 10 days) did not shorten or lessen symptoms compared with placebo.Treatment of the common cold with unrefined echinacea. A randomized, double-blind, placebo-controlled trial.
- In 128 adults with new cold symptoms, 100 mg of Echinacea purpurea three times daily for up to 14 days did not shorten symptoms compared with placebo.Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical…
- In 108 people with frequent colds taking 4 mL of Echinacea purpurea fluid extract twice daily for 8 weeks, the number and duration of colds did not differ from placebo.A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of cold…
- In 108 older adults with chronic obstructive pulmonary disease and a cold-like infection, one daily tablet of Echinacea purpurea with zinc, selenium and vitamin C for 2 weeks led to less severe and shorter flare-ups than placebo, while Echinacea alone did not.Echinacea purpurea along with zinc, selenium and vitamin C to alleviate exacerbations of chronic obstructive pulmonary d…
- In 90 volunteers randomized to Echinacea purpurea capsules or placebo for 8 weeks, Echinacea did not significantly change the number of sick days compared with placebo.Effects of echinacea on the frequency of upper respiratory tract symptoms: a randomized, double-blind, placebo-controlle…
- In 90 otitis-prone children aged 1 to 5 followed for 6 months, echinacea taken at the start of each cold was linked to more ear infections than placebo (65% vs 41% had at least one episode).Echinacea purpurea and osteopathic manipulative treatment in children with recurrent otitis media: a randomized controll…
- In 80 adults with early cold symptoms, Echinacin shortened the full cold from a median of 9 days on placebo to 6 days.Efficacy of Echinacea purpurea in patients with a common cold. A placebo-controlled, randomised, double-blind clinical t…
- In 80 Korean adults, 200 mg daily of an Echinacea purpurea extract for 8 weeks increased natural killer cell activity and some blood immune signals compared with placebo, with no adverse reactions, but did not change self-reported cold symptoms or fatigue.A randomized, double-blind, placebo-controlled study on immune improvement effects of ethanolic extract of Echinacea pur…
- In 61 people prone to respiratory infections taking a berry and Echinacea blend for 60 days, infections fell from 8 to 2 compared with placebo, with throat symptoms also reduced and immune cell signaling changed.Therapeutic Potential of a Natural Blend of Aronia melancarpa, Lonicera caerulea, and Echinacea purpurea Extracts in Tre…
- In 48 healthy adults taking 2.5 ml of Echinacea purpurea three times daily for two weeks around a rhinovirus exposure, infection rates were not reduced compared with placebo.Echinacea purpurea for prevention of experimental rhinovirus colds.
- In 40 healthy young men taking fresh Echinacea purpurea juice by mouth for 14-day periods, immune cell activity and cytokine production did not rise compared with placebo juice.Oral administration of freshly expressed juice of Echinacea purpurea herbs fail to stimulate the nonspecific immune resp…
- In a placebo-controlled crossover trial of 40 healthy men, two weeks of Echinacea purpurea juice had only minor effects on immune cell counts, and the small changes were of questionable importance.Effect of oral administration of freshly pressed juice of Echinacea purpurea on the number of various subpopulations of …
- In 32 people taking Echinacea for 4 weeks, upper respiratory infections lasted about 3.4 days versus 8.6 days with placebo, and the Echinacea group avoided the exercise-related drop in saliva antibodies seen with placebo.Echinacea purpurea and mucosal immunity.
- In 10 adults given a single dose of Echinacea purpurea as tincture or tablets, inflammatory signals in blood cells dropped 23 hours later, though only about a quarter of the active compounds from the tablets were absorbed.Bioavailability and pharmacokinetics of Echinacea purpurea preparations and their interaction with the immune system.
- In adults with acute respiratory infections, the KanJang herbal liquid improved cough, mucus, congestion and feeling of sickness more than the standard drug bromhexine, and shortened recovery by about 2 days, while an Echinacea and Eleutherococcus mix did not differ from bromhexine on most symptoms.Randomized trial of a fixed combination (KanJang) of herbal extracts containing Adhatoda vasica, Echinacea purpurea and …
- An Echinacea-derived cream applied to the skin reduced eczema severity more than the comparator, reduced inflammatory signals in skin cells, and raised skin lipid levels by day 15.Echinacea purpurea-derived alkylamides exhibit potent anti-inflammatory effects and alleviate clinical symptoms of atopi…
- Among hospital workers in Hong Kong during the severe acute respiratory syndrome outbreak, none of the 1063 who took a 2-week herbal supplement caught the illness, versus 0.4% of non-users, and flu-like symptoms and quality of life improved in users.The use of an herbal formula by hospital care workers during the severe acute respiratory syndrome epidemic in Hong Kong…
- In 3160 hospital workers taking a herbal formula for 2 weeks during the SARS outbreak, none contracted the infection, compared with 0.4% of non-consumers, and a subgroup showed significant immune boosting.Using herbal medicine as a means of prevention experience during the SARS crisis.
- In 125 patients treated with laser removal of genital warts, taking an echinacea root extract for 4 months lowered relapse rates over 12 months compared with no extra treatment.Effect of Immunomodulatory Supplements Based on Echinacea Angustifolia and Echinacea Purpurea on the Posttreatment Relap…
- In a small pilot of 18 people after bone marrow transplant for leukemia, some patients took a Chinese herbal formula called Sheng-Yu-Tang for up to 6 months alongside standard care; the abstract reports no results on whether it helped immune recovery, so the pilot only prepared for a larger trial.A Controlled Trial of Sheng-Yu-Tang for Post-Hematopoietic Stem Cell Transplantation Leukemia Patients: A Proposed Proto…
- In volunteers with a natural common cold given Echinilin or placebo for 7 days, the total daily symptom score fell more in the Echinacea group, with raised white blood cell and natural killer cell counts.A proprietary extract from the echinacea plant (Echinacea purpurea) enhances systemic immune response during a common co…
- In cancer patients with depressive symptoms, the herbal formula Xiao-Chai-Hu-Tang improved depression scores and lowered whole-body inflammation compared with placebo.Xiao-Chai-Hu-Tang ameliorates tumor growth in cancer comorbid depressive symptoms via modulating gut microbiota-mediated…
- In 80 athletes taking Echinaforce Forte tablets in an open study without a control group, about 71% stayed free of colds and about 75% rated its efficacy as good or very good.Open, multicenter study to evaluate the tolerability and efficacy of Echinaforce Forte tablets in athletes.
- In a retrospective study of 154 gastric cancer patients, adding a herbal decoction to chemotherapy improved antibody levels (IgA, IgM, IgG) and reduced side effects, though it did not change cancer outcomes.Effects of Yipi Huayu decoction on tumor markers, immune function, and adverse reactions during chemotherapy in gastric …
- In 31 people with infected soft tissue wounds, adding the immune drug thymogen, a silica sorbent and Echinacea tincture cleaned and healed wounds faster and normalized immune measures, though the abstract reports no control group.[Applications of immunomodulators in complex of treatment of the soft tissue purulent wounds].
- In a small pilot study, taking Echinacea, Astragalus or licorice tinctures for 7 days activated T immune cells within 24 hours, with the combination having an additive effect.The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell acti…
- In patients with dust mite asthma and allergic rhinitis, a mixed Chinese herbal formula calmed immune cells that drive allergic reactions in laboratory tests, with less inflammatory signaling and more anti-inflammatory interleukin-10.The immune-modulatory effects of a mixed herbal formula on dendritic cells and CD4+ T lymphocytes in the treatment of du…
- Laboratory tests showed these plant extracts stimulated immune cell activity, and clinical use gave a boost after a single dose but a suppressive effect with daily higher doses; the abstract does not report human group sizes or durations.Immunomodulation with Viscum album and Echinacea purpurea extracts.
Review Totals and Summary
Members Only938 reviews · 95% positive
Shoppers rate this echinacea and goldenseal capsule blend highly: it carries about 932 ratings across the stores, and most reviewers are happy with it. A few raise concerns about the herb itself, a change in the product's appearance, and bottle size. **What buyers say it did for them:** Most use it for immune support, and many take it when they feel a cold coming on or through the winter. One says they "haven't been sick in many years." Another says it can "reduce the intensity of illness, colds and cold sores." One reviewer felt better "instantly" after feeling unwell. One mentions help with pollen and dust allergens, and a couple notice a little more alertness or focus. One reviewer is honest about the uncertainty: "Could be placebo but even if so it's helped." **What they complain about:** The criticisms are few. One buyer gave one star because the capsule contents changed from "a deep green color" to "a pale yellowish color" in a new bottle, and they no longer trust the brand after years of use. A three-star reviewer found the product effective but felt the bottle runs out too fast for the daily dose and suggested buying a larger size. Several reviewers also point out that goldenseal needs care, noting that it is "dangerous for some people," that daily use calls for regular breaks, and that it should not be taken in pregnancy. These are the reviewers' own cautions. **Taste, smell, pill size or form:** Reviews call the capsules "easy to swallow" and "easy to take," with "no weird aftertaste." One says they taste good. Another found the root flavor strong, comparing it to "a dark expresso shot." One reviewer liked taking two capsules a day, which they find simpler than two separate products. **Value for money:** Buyers who mention price are positive. One says "They are a good price," noting about 7.4 cents per capsule in March 2026. Another likes the "great prices" at Walmart. The three-star reviewer's point about the bottle size is partly a value concern, since the supply doesn't last long at the full daily dose. **Who it seems to suit and who it did not:** It seems to suit adults looking for everyday or seasonal immune support, especially people who want echinacea and goldenseal in one product. Some repeat buyers have used it for years. It suited less well the long-time user who saw the color change and lost confidence, and the buyer who found one bottle too small for daily use. Anyone considering it should note the goldenseal cautions reviewers raised. Only the capsule reviews were used here. Reviews of other forms of this product, such as gummies or powder, were left out.
Biohacker Summary
Members Only3 of 10 recommend it
Our biohacker panel has not discussed this product’s ingredients yet.
RAL Summary
Members OnlyTier 4 for Immune Health
The tier 2 grade rests largely on studies of Chinese herbal formulas that are not in this product, goldenseal was not studied at all, and the echinacea trials disagree. The stated 90 percent improvement rate also does not match 28 of 44 studies. So it is graded Tier 4, lower than the rules alone gave.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 12 of the 44 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Immune system, Respiratory system
Combine with: For immune support, pair this blend with vitamin C (500-1000 mg), zinc (15-30 mg, short term), and vitamin D3 with K2, which help support normal immune function. Elderberry extract and propolis can complement echinacea during seasonal challenges, and vitamin A or quercetin may add further support. For the cellular and DNA repair goal, a better approach would be products containing NMN or NR, resveratrol, CoQ10, alpha-lipoic acid, and astaxanthin, which target mitochondrial function and oxidative stress. Avoid long-term continuous use of goldenseal, and consult a healthcare provider if you take medications, since berberine and goldenseal can interact with drugs metabolized by CYP enzymes.
Possible side effects: Mild side effects were more common with echinacea in a review of trials in children, while an adult trial reported no adverse reactions.
Supplement Facts
Proprietary Herbal Blend 900 mg
| Proprietary Herbal Blend | 900 mg | † |
Other ingredients: Ingredients.
Directions: Suggested Use: Adults, take two capsules twice daily, preferably with a meal.
Barcode (UPC) 605388325556 · Label source: NIH label database · Report a label change
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Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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