Thorne Ovarian Care Review

Ovarian Care is a Thorne supplement presented as a mixed-berry flavored powder designed to promote healthy ovarian function and support natural fertility, with a focus on hormonal balance and family planning. The product page describes a blend of nutrients and plant extracts intended to help maintain menstrual regularity, support a healthy insulin response, and provide antioxidant protection to help preserve egg quality and reproductive health. The formula is built around clinically studied ratios of myo-inositol and D-chiro-inositol, a CoQ10 phytosome, methylated folate, and polyphenols from wild blueberry, pomegranate and green tea. The label lists 2000 mg of myo-inositol, 50 mg of D-chiro-inositol, 150 mg of CoQ10 phytosome, 667 mcg DFE of folate as 5-MTHF, 50 mg of green tea extract, 25 mg of pomegranate extract and 50 mg of wild blueberry complex per one scoop serving, with 60 servings per container. The recommended use is to mix one scoop with at least eight ounces of water two times daily. Other ingredients are citric acid, flavor, medium chain triglyceride oil and rebaudioside A from stevia. The page states that the product is gluten-free, dairy-free, soy-free, and contains only natural colors and flavors. It is described as third-party tested for purity and potency. Thorne says the formula received the 2024 Women's Health Innovation Award from MedTech Breakthrough. The product is presented as a powder so that buyers do not need to take many capsules, while still providing what the page calls a sufficient amount of each nutrient used in clinical studies. The details section explains the inositol ratio of 40:1 myo-inositol to D-chiro-inositol and says it may enhance insulin sensitivity, support balanced hormone levels to promote ovulation and menstrual regularity, and benefit clear skin and healthy hair growth where wanted. The CoQ10 phytosome is described as supporting mitochondrial energy production, reproductive health, ovarian response during assisted reproduction, and protection of ovarian reserve. The folate is presented as methylfolate for people with challenged folate metabolism, including those with an MTHFR polymorphism. The polyphenols are described as antioxidants that support a healthy inflammatory response. The warnings section says the product is contraindicated for anyone with a history of hypersensitivity to any ingredient. Pregnant users are advised to consult a health-care practitioner before use. It also notes that 5-MTHF is not recommended alongside a med cancer therapy because it can interfere with that treatment's anti-neoplastic activity. The page includes a comparison with Hormone Advantage and Basic Prenatal, and lists a price of $62 for one container, or $55.80 with a subscription. Subscription options and HSA or FSA eligibility are also shown.

Product Focus: Hormone Balance for WomenAlso covers:Sexual healthMetabolism
Tier ⓘ
Tier 3 · Rank 7
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 7 within Tier 3 for Hormone Balance for Women; 29 of 50 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
70 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
83% of 1,937
Biohacker Mentions
9 of 10
Cost per month
$62

Study, Trial or Testing Result Summary

Members Only65 human studies · 35 improved
65 human studies35 improved24 no effect1,932,220 people studied

The main ingredient is inositol, at a full daily amount. In women with severe premenstrual mood disorder, myo-inositol improved daily symptoms, depression and overall severity more than a dummy pill [1], but a tiny trial using a much higher dose found no benefit [2]. In women going through the menopausal transition, 4 grams a day lowered thyroid-stimulating hormone and insulin, though without a comparison group [3]. A pooled analysis in polycystic ovary syndrome found myo-inositol did not improve insulin resistance [4]. Green tea extract improved insulin, fat burning and waist size in a small trial of overweight women past menopause [5], but a larger trial found no consistent change in estrogen or testosterone [6]. Coenzyme Q10 did not change egg quality or pregnancy rates in a small fertility trial [7]. Folate here is well below the 5 milligram dose studied, and those studies were mixed for hot flushes [8][9]. Pomegranate is present only in a trace amount, far below the studied dose [10]. Wild blueberry has no human studies for this goal. Animal and cell studies are never counted.

See all 65 studies →Hide the studies

Review Totals and Summary

Members Only1,937 reviews · 83% positive
1,937 reviews · Store.mayoclinic 1,117 · Amazon 397 · Vitacost 222 · Thorne 132 · Walmart 69
83% positive5% neutral12% negative

Across the stores that sell it, Thorne Ovarian Care powder carries about 820 ratings, and most are positive. Buyers mainly praise cycle regulation and PCOS-related changes, while the taste and how the powder mixes draw the most complaints. Reviews of other forms of the product were left out; this covers the powder only. **What buyers say it did for them:** Cycle changes are the most common story. One buyer whose cycles ran 40-50 days said, "I ovulate on time and my LH levels are higher," and another with PCOS went from 39 days to 28. After a miscarriage, a buyer reported "my last 3 cycles have all been 27 days." Others describe fewer sweet cravings, better sleep, more energy and clearer skin. One said they were "down 15 lbs." One buyer reported mood swings "muted nearly completely." Two buyers reported pregnancies after using it, one after about three months of on-and-off use and one after more than two years of infertility (per a store summary). Some praise is only general, such as "Best supplement ever." **What they complain about:** The main complaint is the flavor and texture. One buyer says "it does not mix," even after five minutes with an electric whisk, and had to take it "like a shot." Another reported that the powder is "supposed to be taken twice daily," yet her wife found it too artificial and didn't finish half the bottle. One reviewer also admitted that the powder "works," despite disliking it. One store's AI summary describes mixed opinions on how well it works for menstrual cycles, but the written reviews shown don't back that up. **Taste, smell, form:** Opinions split. One buyer finds it sweet but manageable: "I do 2 scoops in my 40z Stanley and sip." Another says "I see a lot of reviews about the taste being terrible," yet drinks it with 8oz of water and chases it with something else. Other buyers on one store's page call the taste pleasant and easy to take daily, or delicious. Another finds it quite strong and suggests mixing it with something flavorless like unflavored collagen, and would prefer an unflavored version. Buyers also mention a convenient size and good packaging. **Value for money:** Reviewers don't discuss price directly. One said it is "worth it if you want to see results," and another chose it because it had the most myo-inositol and CoQ10 they could find. Another preferred a competing product that blends better with similar ingredients. **Who it seems to suit and who it didn't:** It seems to suit people with PCOS, irregular or long cycles, or those preparing to conceive. It also appeals to people coming off birth control who want a natural way to regulate their cycle, and to buyers who trust the Thorne brand. It suited people less when they were sensitive to flavor or texture. The wife in the 2-star review switched products, and the 1-star reviewer could not get it to dissolve. A few reviews were only about shipping ("Fast shipping, good packing") and say nothing about results yet.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Green tea, the main ingredient, is used by most of the panel, though only one person gives it a clear recommendation and several simply mention it. Four of them drink it for focus, calm energy, morning routine or visceral fat loss, and two others point to its catechins and EGCG for calorie burning and cell cleanup. Two of them suggest pairing it with lemon so more of the catechins survive digestion, and one rotates it with coffee every couple of days. One panelist warns that very high doses of EGCG or green tea extract could harm the liver, and another says green tea extract did not extend lifespan in animal studies. No one gave a dose in cups or milligrams beyond one person's two cups a day, and no one said they stopped using green tea. Folate, inositol, coenzyme Q10 and pomegranate are smaller ingredients in this product.

See all 10 biohackers →Hide the biohackers
  • Siim Land · Green Tea · recommends
    • 31 Oct 2026 · recommends · Instagram ↗
      States that green tea is very effective for visceral fat loss due to its polyphenol content.
    • 27 Oct 2026 · uses · Instagram ↗
      Personally drinks 2 cups of green tea a day and made it one of the small changes while reducing his visceral fat.
    • 19 Oct 2026 · neutral · YouTube ↗
      Mentions that green tea's EGCG has stimulated autophagy in cultured liver cells and mouse experiments by increasing AMPK.
    • 11 Oct 2026 · uses · YouTube ↗
      Consumed more polyphenol-rich foods, including green tea, to reduce visceral fat.
    • 30 Sep 2026 · uses · YouTube ↗
      Mentions that he drank green tea, which targets visceral fat, as one of the things he did to reduce visceral fat.
    • 26 Sep 2026 · uses · X ↗
      Drinks 1-3 cups of green tea a day, noting that there are multiple lines of evidence suggesting it improves various health markers and may have longevity benefits.
    • 26 Sep 2026 · recommends · X ↗
      States that green tea is one of the healthiest beverages in the world, improving cardiovascular disease risk factors, heart health, metabolic health markers, targeting all hallmarks of aging, reducing visceral fat, and being associated with lower mortality.
    • 25 Sep 2026 · uses · YouTube ↗
      When dropping his visceral fat, Siim Land drank around one to three cups of green tea per day, usually in the morning and before exercise, and believes it contributed to visceral fat loss.
    • 19 Aug 2026 · Inositol · neutral · X ↗
      States that Inositol has been shown to improve blood sugar and insulin sensitivity.
    • 19 Aug 2026 · Inositol · neutral · X ↗
      States that Inositol has a key role in glucose metabolism and that grapefruit is one of the richest sources of it.
    • 30 Jul 2026 · uses · Instagram ↗
      Drank 2–3 cups of green tea per day to reduce visceral fat.
    • 28 Jul 2026 · uses · X ↗
      Reduced visceral fat by adding 2 cups of green tea per day.
    • 20 Jul 2026 · Inositol · uses · X ↗
      He takes 900 mg of Inositol before bed for sleep.
    • 29 Jun 2026 · Inositol · uses · X ↗
      He takes 900 mg of inositol before bed for sleep.
  • Thomas DeLauer · Green Tea · uses
    • 30 Oct 2026 · uses · YouTube ↗
      Now rotates green tea with coffee, having green tea for two days, then coffee for two days, to maintain energy and benefit from different antioxidant profiles. He previously focused too much on green tea and neglected coffee.
    • 29 Oct 2026 · uses · YouTube ↗
      Combines MCT oil with matcha green tea in a cognitive cocktail, finding that green tea provides more mental benefits than coffee for focus and calm energy.
    • 16 Oct 2026 · recommends · Facebook ↗
      Explains that green tea's catechin benefits often diminish in the intestines, with less than 20% surviving digestion, but adding citrus can reclaim these benefits by about 5x.
    • 16 Oct 2026 · recommends · Facebook ↗
      Recommends adding citrus, specifically lemon, to green tea to reclaim the benefits of catechins, as it can leave 80% of them intact.
    • 11 Oct 2026 · Pomegranate · recommends · YouTube ↗
      Recommends consuming pomegranates consistently, even daily, to develop the gut bacteria, specifically Akkermansia, that can extract Urolithin A from them.
    • 11 Sep 2026 · recommends · YouTube ↗
      Recommends sipping green tea while walking fasted in the morning to help extend the fat oxidation window.
    • 31 Aug 2026 · recommends · YouTube ↗
      Recommends one to three small cups of green tea, ideally in the morning, as consistent consumption over two to three weeks increases BDNF due to EGCG.
    • 20 Aug 2026 · Pomegranate · recommends · Instagram ↗
      Recommends pomegranate for lung health, noting that ellagitannins provide airway antioxidant defense.
    • 15 Aug 2026 · recommends · YouTube ↗
      Recommends switching to a good quality green tea first thing in the morning because it is lower in caffeine and contains theanine, which has a cortisol-blunting effect, balancing out the stimulation.
    • 12 Aug 2026 · Pomegranate · recommends · YouTube ↗
      Recommends pomegranates to support specific bacteria that produce butyrate.
    • 11 Aug 2026 · recommends · Instagram ↗
      Recommends green tea, mentioning its EGCG content.
    • 10 Aug 2026 · uses · Instagram ↗
      Would want green tea for its EGCG, which is a good antioxidant, especially for managing stress.
    • 4 Aug 2026 · recommends · Instagram ↗
      Recommends green tea as an alternative to pre-workouts, highlighting caffeine as the key ingredient.
    • 2 Aug 2026 · Pomegranate · uses · Instagram ↗
      Rates pomegranate arils as a 9.5, mentioning that punicalagins are converted into urolithin A by the gut, providing a super cool overall benefit.
  • Dr. Eric Berg · Green Tea · neutral
    • 17 Oct 2026 · neutral · Instagram ↗
      Suggests pairing green tea with lemon for better absorption.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that birth control pills deplete the body of folate, which is needed for the brain to make serotonin.
    • 18 Oct 2026 · Coenzyme Q10 · neutral · YouTube ↗
      Mentions that grass-fed liver has coenzyme Q10.
    • 2 Oct 2026 · Coenzyme Q10 · recommends · YouTube ↗
      Recommends that anyone with a med prescription should also take coenzyme Q10, specifically the ubiquinol form, to support heart and muscle function.
    • 30 Sep 2026 · Pomegranate · recommends · YouTube ↗
      Recommends pomegranate seeds as a top food to help increase nitric oxide.
    • 18 Sep 2026 · recommends · Instagram ↗
      Suggests incorporating anti-cancer foods like green tea to help prevent pancreatic cancer.
    • 12 Sep 2026 · Pomegranate · recommends · YouTube ↗
      Recommends consuming pomegranate seeds to increase nitric oxide.
    • 10 Sep 2026 · recommends · X ↗
      Recommends replacing coffee with green tea.
    • 10 Sep 2026 · Coenzyme Q10 · neutral · Facebook ↗
      Notes that Merck filed a patent for a med combined with coenzyme Q10, but never added it back into the formula, and that major heart organizations do not recommend taking coenzyme Q10 alongside meds.
    • 10 Sep 2026 · Pomegranate · recommends · YouTube ↗
      Recommends pomegranate seeds as a potent heart healer, especially for decreasing the risk of plaque, supercharging nitric oxide, and helping to reduce blood pressure.
    • 7 Sep 2026 · neutral · Facebook ↗
      Mentions green tea as an ingredient that can bring something different to the table for liver health.
    • 5 Sep 2026 · Coenzyme Q10 · recommends · YouTube ↗
      Recommends taking coenzyme Q10, specifically ubiquinol, to prevent the side effects of meds, especially for those experiencing muscle weakness, pain, fatigue, or exercise intolerance. He suggests a dose of 200 to 400 mg, or even up to 1200 mg a day for some individuals.
    • 3 Sep 2026 · Folate · neutral · Facebook ↗
      Dr. Berg mentions that fermented dairy contains vital nutrients, including folate.
    • 25 Aug 2026 · recommends · Facebook ↗
      Recommends replacing coffee with green tea as a step towards improving energy levels and brain functioning.
  • Dr. Mark Hyman · Green Tea · neutral
    • 30 Sep 2026 · neutral · YouTube ↗
      Mentions that EGCG from green tea activates thermogenesis, contributing to calorie burning.
    • 23 Oct 2026 · Inositol · recommends · Facebook ↗
      Lists inositol as a supplement that helps balance neurotransmitters and can help lower anxiety or depression symptoms.
    • 21 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
    • 31 Aug 2026 · Folate · uses · YouTube ↗
      Optimized a child's nutrient status with folate, as the child had low folate levels and was not eating greens.
    • 29 Jul 2026 · uses · YouTube ↗
      States he was using green tea to stimulate the NRF2 pathway and open up detox.
    • 28 Jul 2026 · Folate · neutral · Facebook ↗
      Notes that a med depletes folate.
    • 22 Jul 2026 · Folate · recommends · YouTube ↗
      States that folate is a nutritional deficiency that impacts mental health.
    • 20 Jul 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 8 Jul 2026 · Folate · uses · YouTube ↗
      Recounts giving a patient with MCI high-dose methylfolate, along with B12 shots and B6, which completely cured her MCI.
    • 29 Jun 2026 · Folate · recommends · Facebook ↗
      Recommends folate with vitamin B6 and B12 as supplements with strong evidence for PMS.
    • 24 Jun 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 3 Jun 2026 · Folate · recommends · YouTube ↗
      Explains that folate metabolism is very involved in neurotransmitter function and mood, and that folate can be a treatment for some cases of depression, especially for those with MTHFR genetic variants.
    • 15 May 2026 · Pomegranate · neutral · YouTube ↗
      Mentions that pomegranate juice has been known for a long time to be healthy and confer health benefits, but the mechanism was not clear until ellagitannins and their metabolism into urolithin A by the microbiome were discovered.
  • Andrew Huberman · Green Tea · uses
    • 28 Sep 2026 · uses · YouTube ↗
      Drinks green tea and believes it has very positive cognitive benefits in terms of focus.
    • 22 Oct 2026 · Inositol · neutral · Podcast ↗
      Discusses Myo-Inositol as a tool for middle-of-the-night waking.
    • 6 Aug 2026 · Inositol · neutral · Podcast ↗
      Discusses Myo-inositol as a supplement that can impact serotonin.
    • 6 Aug 2026 · Inositol · uses · YouTube ↗
      Has been taking 900 mg of myo-inositol every third night or so to test its ability to improve sleep, finding the depth and quality of sleep to be remarkable.
    • 20 Jul 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 16 Jul 2026 · Inositol · neutral · Podcast ↗
      Mentions inositol as a nutraceutical that can be used for bipolar disorder.
    • 16 Jul 2026 · Inositol · uses · YouTube ↗
      Personally takes 900 mg of myo-inositol every third night or so to improve sleep and for its anti-anxiety effect during the day, but not for bipolar disorder.
    • 13 Jul 2026 · uses · X ↗
      Uses Athletic Greens AG1 in the morning for gut health.
    • 9 Jul 2026 · Inositol · neutral · Podcast ↗
      Mentions Inositol as a nutraceutical for OCD.
    • 9 Jul 2026 · Inositol · recommends · YouTube ↗
      Highlights myoinositol, stating that 900 milligrams or higher dosages can improve sleep and reduce anxiety, and suggests more systematic exploration of nutraceuticals like inositol for OCD treatment, especially in combination with behavioral therapies.
    • 6 Jul 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 6 Jul 2026 · Coenzyme Q10 · uses · YouTube ↗
      Personally takes Omega-3 and Coenzyme Q10 every day, noting they are known to support cardiovascular health, cellular health and energy, and brain health.
    • 8 Jun 2026 · Coenzyme Q10 · uses · YouTube ↗
      Personally takes coenzyme Q10 every day, noting it supports cardiovascular health, cellular health, energy, and brain health.
    • 13 Apr 2026 · Inositol · recommends · YouTube ↗
      Mentions inositol for PCOS, stating it decreases insulin resistance and offers a huge benefit.
  • Dave Asprey · Green Tea · warns
    • 9 Sep 2026 · warns · YouTube ↗
      Warns that very high doses of EGCG or green tea extract could cause harm to the liver.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 12 Oct 2026 · Pomegranate · stopped · Facebook ↗
      Would have to eat a ridiculous pile of pomegranates every day to get enough Urolithin A, and they are not doing that.
    • 1 Sep 2026 · Coenzyme Q10 · uses · YouTube ↗
      States he takes 300 mg of Coenzyme Q10 every day for 20 years because it is necessary for mitochondria to function and is important for longevity, noting that meds lower it.
    • 5 Aug 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as a better option than folic acid.
    • 18 Jul 2026 · Pomegranate · neutral · YouTube ↗
      Notes that pomegranates contain compounds that gut bacteria convert into urolithin A, which activates mitophagy through a unique biological pathway.
    • 11 Jun 2026 · Folate · recommends · YouTube ↗
      Dave Asprey notes that 80% of their clients have a problem absorbing certain forms of folate, and when the exact form of folate or folinic acid is dialed in, clients experience shifts, with the brain waking up as one of the first improvements.
    • 21 May 2026 · Pomegranate · warns · Podcast ↗
      Dave notes that eating pomegranates or taking cheap pomegranate extract does not work for most people to produce urolithin A.
    • 21 May 2026 · Pomegranate · warns · YouTube ↗
      Dave Asprey used to eat pomegranates from his backyard tree but would get sore joints because pomegranate seeds have a lot of oxalates and sugar.
    • 16 May 2026 · Coenzyme Q10 · recommends · YouTube ↗
      Recommends coenzyme Q10 (CoQ10) to support mitochondria, as it helps generate energy and fights oxidative stress.
    • 16 May 2026 · Inositol · uses · X ↗
      He takes 900 mg of Inositol before bed for sleep.
    • 5 May 2026 · neutral · YouTube ↗
      Mentions green tea as a source of EGCG but notes it also contains oxalates.
    • 26 Apr 2026 · Pomegranate · warns · Podcast ↗
      Discusses the massive problem with trying to get Urolithin A from pomegranates, as only 30% of people have the right gut bacteria to even make it.
    • 17 Apr 2026 · Pomegranate · neutral · X ↗
      Mentions that one would need six cups of pomegranate juice a day to hit the minimum effective dose of Urolithin A.
  • Ben Greenfield · Green Tea · uses
    • 20 Aug 2026 · uses · YouTube ↗
      Drinks green tea in the morning as part of her quiet time.
    • 15 Oct 2026 · Pomegranate · neutral · YouTube ↗
      Questions the efficacy of pomegranate extract for plaque melting, asking how an enzyme can get through stomach acid and if the gut bacteria can utilize its chemical trash to make K.
    • 12 Oct 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as an active form of folate that the body can use directly without conversion.
    • 21 Sep 2026 · Inositol · neutral · Facebook ↗
      Notes that inositol has solid research behind it for fertility.
    • 19 Sep 2026 · Inositol · recommends · YouTube ↗
      Recommends Inositol at 1 to 5 grams per day for women, noting its involvement in FSH signaling and citing trials showing fewer immature oocytes and more high-quality embryos in women undergoing IVF.
    • 19 Sep 2026 · Inositol · neutral · Podcast ↗
      He discusses inositol for female fertility.
    • 9 Sep 2026 · Inositol · neutral · X ↗
      Myo-inositol has the same insulin-sensitivity mechanism as in men and is tied to egg quality.
    • 8 Sep 2026 · Inositol · neutral · X ↗
      Mentions Inositol with a dose of 1-5 grams/day.
    • 30 Jul 2026 · Pomegranate · neutral · YouTube ↗
      Mentions pomegranates as a food that increases angiogenesis, as outlined in Dr. William Lee's book 'Eat to Beat Disease'.
    • 9 Jul 2026 · Folate · recommends · YouTube ↗
      Recommends bioavailable folate, not synthetic folic acid, as folate deficiencies seem to impact hearing health in older individuals.
    • 4 Jun 2026 · Pomegranate · neutral · YouTube ↗
      Notes that 1,000 mg of urolithin A is equivalent to juicing 60 pomegranates, which would also result in a lot of sugar.
    • 25 Apr 2026 · uses · YouTube ↗
      States that Nuchido Time Plus includes green tea extract for its high level of EGCG, which inhibits the methylating enzyme NNMT, ensuring nicotinamide is recycled rather than excreted.
    • 18 Apr 2026 · Folate · recommends · YouTube ↗
      Recommends introducing methylfolate into the diet to address high homocysteine levels.
    • 26 Mar 2026 · recommends · YouTube ↗
      Suggests that one could do a carnivore diet and still have a cup of green tea in the morning to introduce hormetic stressors.
  • Bryan Johnson · Green Tea · uses
    • 7 Mar 2026 · uses · X ↗
      Takes Athletic Greens AG1 in the morning for gut health.
    • 1 Jul 2026 · Pomegranate · uses · X ↗
      Uses pomegranate juice as an ingredient in Nutty Pudding.
    • 4 May 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 15 Apr 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 8 Apr 2026 · Inositol · uses · X ↗
      Takes 900 mg of inositol before bed for sleep.
    • 31 Mar 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 20 Mar 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 10 Mar 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 7 Mar 2026 · Inositol · uses · X ↗
      Takes 900 mg of Inositol before bed for sleep.
    • 16 Oct 2025 · Pomegranate · uses · YouTube ↗
      Uses pomegranate seeds because they have unique polyphenols that protect cholesterol from oxidation, which improves blood flow.
    • 23 Dec 2023 · Pomegranate · uses · YouTube ↗
      Finishes his Nutty Pudding with 60 mL of pomegranate juice for antioxidants and heart health.
    • 27 Jul 2023 · Pomegranate · uses · YouTube ↗
      Includes pomegranate juice in his Nutty Pudding, which he consumes an hour after his Super Veggie.
    • 26 Jun 2023 · Pomegranate · uses · YouTube ↗
      Has pomegranate seeds in his fridge.
    • 25 Jan 2023 · Pomegranate · uses · YouTube ↗
      Includes pomegranate juice in his 'Nutty Pudding' as part of his fat profile for the third meal of the day.
  • Peter Attia · Green Tea · neutral
    • 8 Feb 2021 · neutral · YouTube ↗
      Explains that green tea extract was tested due to popular reputation and traditional medicine claims, but it did not extend the lifespan of animals in their studies.
    • 19 Aug 2024 · Folate · recommends · YouTube ↗
      Highlights folate supplementation as a significant practical progress in nutrition science, which has radically reduced spinabifida.
    • 24 Oct 2023 · Folate · uses · YouTube ↗
      Takes Jarrow methylfolate to keep homocysteine levels below nine, taking the lower of two available strengths once a day.
    • 23 Oct 2023 · Folate · uses · YouTube ↗
      Takes Jarrow methylfolate, a methylated version, once a day at the lower of two strengths, to keep homocysteine levels below nine.
    • 28 Aug 2023 · Folate · neutral · YouTube ↗
      Mentions that in a mouse model for obesity, the amount of folate given to the mother mouse during pregnancy affects the epigenetics of her offspring, leading to changes in coat color and obesity.
    • 5 Jun 2023 · Folate · uses · YouTube ↗
      Personally takes methylfolate to help get homocysteine into the desired zone and prefers the Jarrow brand.
    • 7 Nov 2022 · Coenzyme Q10 · neutral · YouTube ↗
      Notes there isn't good data that Coenzyme Q10 prevents a med Associated muscle symptoms, but doesn't object if patients want to take it because it makes them feel better about taking a med.
    • 18 Jan 2020 · Folate · uses · YouTube ↗
      Takes methyl folate as a supplement.
    • 7 Jan 2020 · Folate · neutral · YouTube ↗
      Considers 400 micrograms of methylfolate in a typical supplement to be reasonable and more than sufficient, but notes that if it doesn't fix homocysteine, the deficit lies elsewhere.
    • 31 Dec 2019 · Folate · uses · YouTube ↗
      Uses and vouches for Jarrow's combined lozenge of methylfolate and methyl B12, stating they choose specific supplements because they know they work and are verified by blood tests.
  • Dr. Rhonda Patrick · Green Tea · neutral
    • 4 Sep 2013 · neutral · YouTube ↗
      Dr. Patrick mentions that catechins and polyphenols are found in things like green tea, dark chocolate, turmeric, blueberries, and other purple pigmented fruits and vegetables, as well as red wine.
    • 28 Sep 2026 · Folate · recommends · YouTube ↗
      Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
    • 14 Sep 2026 · Pomegranate · neutral · YouTube ↗
      Explains that pomegranate contains polyphenols called ellagitannins, which gut bacteria convert into Urolithin A, but there's significant individual variation in how much Urolithin A people actually produce from eating it.
    • 7 Nov 2025 · Pomegranate · neutral · Facebook ↗
      Some people produce urolithin A after eating pomegranates and walnuts, but others need to supplement directly.
    • 2 Sep 2025 · Inositol · uses · Instagram ↗
      Has found myo-inositol helps calm "mental chatter" before bed, although it is not strongly evidenced as a sleep aid.
    • 20 Aug 2025 · Folate · neutral · Instagram ↗
      Notes that dark leafy greens are a great source of folate.
    • 5 Aug 2025 · Inositol · uses · Podcast ↗
      Discusses why and how much myo-inositol they took.
    • 26 Jun 2025 · Inositol · uses · Facebook ↗
      Rhonda's current supplement routine includes Myo-inositol.
    • 27 Dec 2023 · Folate · recommends · YouTube ↗
      States that for his mother, who is homozygous for MTHFR, methyl folate along with a high dose B supplement is necessary to prevent her homocysteine and blood pressure from going high.
    • 30 May 2016 · Folate · neutral · YouTube ↗
      Dr. Patrick mentions that her smoothie is rich in folate, which is required for producing thymine and prevents DNA strand breaks.
    • 11 Aug 2015 · Folate · uses · YouTube ↗
      Has experimented with L-methylfolate in the past to lower homocysteine, as he is a poor methylator.
    • 19 Mar 2015 · Folate · recommends · YouTube ↗
      Dr. Patrick states that studies have shown supplementing with 5-methyltetrahydrofolate can successfully circumvent some shortcomings of MTHFR gene polymorphisms and lower homocysteine levels.
    • 6 Jan 2015 · Folate · uses · YouTube ↗
      Dr. Patrick states that her smoothie, containing spinach, has around 480 micrograms of folate, which is essential for the incorporation of thymine into DNA and is very important in regulating epigenetics.
    • 1 Feb 2014 · Folate · recommends · YouTube ↗
      Dr. Patrick states that adequate levels of folate have been shown to prevent cancer, and conversely, inadequate levels can damage DNA, which is known to cause cancer.

RAL Summary

Members OnlyTier 3 for Hormone Balance for Women

The tier rests on green tea, but its largest positive trial tested green tea catechins combined with indole-3-carbinol, not green tea alone, and the larger green tea extract trials found no change in sex hormones. So it is graded Tier 3, lower than the rules alone gave.

Where the evidence disagrees: 24 of the 65 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Reproductive system, Endocrine system, Metabolic system

Combine with: For women using this product for its intended ovarian and hormonal purpose, complementary supplements include vitamin D3, folate (methylfolate), omega-3 fish oil, magnesium, and chromium or berberine for additional insulin and metabolic support. Zinc and selenium can support reproductive and antioxidant pathways, and CoQ10 may support egg and mitochondrial health. If digestive sensitivity is also a concern, consider separately adding a targeted gut-support option such as a multi-strain probiotic, peppermint oil capsules, digestive enzymes, or partially hydrolyzed guar gum, and take NAC/inositol with food to minimize GI discomfort.

Possible side effects: No major side effects reported in the studies; buyers mainly complain about the taste and that the powder does not mix well.

Supplement Facts

Includes 0 g Added Sugars 0 · Folate 667 mcg DFE · 40:1 Inositol Blend 2050 mg
Supplement Facts
Serving Size One Scoop (3.7 g)
Servings Per Container 60
Amount Per Serving% Daily Value
Calories11
Total Carbohydrate2 g
Total Sugars1 g
Includes 0 g Added Sugars
Folate667 mcg DFE
40:1 Inositol Blend2,050 mg†
Coenzyme Q10 Phytosome††150 mg†
Wild Blueberry Complex50 mg†
Green Tea extract (leaf)50 mg†
Pomegranate extract (whole fruit)25 mg†
† Daily Value not established.

Other ingredients: Flavor, Medium Chain Triglyceride Oil, Citric Acid, Rebaudioside A (from stevia).

Directions: Mix 1 scoop with at least 8 ounces of water two times daily or as recommended by your health-care practitioner.

Label source: Reverseagelab · Report a label change

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Our articles on this subject

Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.