Thorne Vitamin D-5,000 - NSF Certified for Sport Review
Thorne Vitamin D-5,000 - NSF Certified for Sport, sold here in a 60 serving bottle of capsules, provides 5,000 IU of vitamin D3 in each capsule. The page describes the product as a way to get the vitamin D the body needs when sunlight and diet fall short. Thorne states that direct sunlight is a natural source of vitamin D, but many individuals, especially the elderly, do not get enough from sunlight or their diet. The product is presented as an easily absorbed form of vitamin D. Thorne notes that vitamin D3 is a more potent and better absorbed form than vitamin D2, which is why this formula uses D3. The listed benefits include support for healthy teeth and bones, promotion of lean muscle mass and help maintaining muscle strength, enhancement of the absorption and retention of calcium, support for healthy brain function, and promotion of cardiovascular health and immune function. The page lists groups who may benefit: people who rarely go outdoors, live in northern latitudes, or have a darker skin tone; people with limited sun exposure due to occupation, clothing, or indoor athletics; people who regularly wear sunscreen with an SPF above 8; older adults, since the risk of deficiency increases with age beginning at 50; people with chronic conditions such as bowel disease or gastric bypass that reduce fat absorption; and people who are obese. Usage is one capsule daily, swallowed with water, preferably at the same time each day, with or without food. The page says the optimal amount of vitamin D varies by person and that supplementation should be individualized, and it notes that Thorne's D-1,000 or D-5,000 can be an ideal way to maintain optimal vitamin D levels in healthy individuals. The product contains no lactose and no preservatives such as BHT, BHA, sodium benzoate, and sorbic acid, and it is free from lactose, gluten, soy, and preservatives according to the summary. The product is NSF Certified for Sport. The page explains that every batch is tested for compliance with label claims and for the absence of nearly 300 substances banned by many major athletic organizations. The FAQ says each ingredient is tested for identity, purity, and potency, including checks for heavy metals, pesticides, and harmful microbes. Warnings state that the product is contraindicated in anyone with a history of hypersensitivity to its ingredients, and that pregnant people should consult a health-care practitioner before use. The page reports no known adverse interactions or contraindications at publication date. The FAQ also discusses pairing with vitamin K2, noting that vitamin D3 and vitamin K2 work together, and that anyone taking meds should consult a health-care professional before using vitamin K containing supplements.
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Study, Trial or Testing Result Summary
Members Only13 human studies · 2 improved
This product gives vitamin D at a full dose, above the amount studied and above the daily recommended limit, so members can take less if they wish. The human evidence for bone health is mixed. A review of older adults found that 700 to 800 international units a day cut hip fractures by 26% and other non-spine fractures by 23%, while 400 units a day did not help [1]. A trial found that children whose mothers took 1,000 units a day during pregnancy had denser bones at ages 6 to 7 [2]. Other reviews disagree. A review of nine studies found no clear drop in fractures [3]. In women after menopause without thinning bones, vitamin D improved some bone turnover measures, but fewer fractures could not be confirmed [4]. In women with thinning bones, calcium plus vitamin D slightly improved pelvic bone density but not spine or hip density and did not reduce fractures, though this tested a combination with calcium [5]. In kidney transplant patients, vitamin D-like drugs, not this vitamin itself, improved bone density without fewer fractures [6]. Animal and cell studies are never counted.
See all 13 studies →Hide the studies
- In 11 trials of 43,869 postmenopausal women with osteoporosis, calcium plus vitamin D modestly improved pelvic bone density but not spine, neck of femur or total hip density, and did not reduce fractures.The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausa…
- This review of smartphone apps for osteoporosis self-management did not test vitamin D supplements and found no significant effect on vitamin D intake.Digital Health Technologies for Long-term Self-management of Osteoporosis: Systematic Review and Meta-analysis.
- In trials of older adults, 700 to 800 IU a day of vitamin D cut hip fracture risk by 26% and other nonvertebral fractures by 23%, while 400 IU a day gave no significant benefit.Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
- Across nine studies, vitamin D3 did not significantly reduce nonvertebral or vertebral fractures versus placebo or calcium alone, with only a borderline trend toward fewer falls.The effect of cholecalciferol (vitamin D3) on the risk of fall and fracture: a meta-analysis.
- In 23 trials of 1,209 kidney transplant recipients, vitamin D analogues (2 trials, 51 patients) improved lumbar spine and femoral neck bone density versus no treatment, but no trial showed fewer fractures.Interventions for preventing bone disease in kidney transplant recipients: a systematic review of randomized controlled …
- In 18 small trials of 576 children with chronic kidney disease, vitamin D preparations lowered parathyroid hormone levels, but there were few data on growth or bone deformities and no clear differences between preparations.Interventions for metabolic bone disease in children with chronic kidney disease.
- One small trial of 39 people with sickle cell disease found vitamin D3 for six weeks raised blood vitamin D and reduced pain days versus placebo, but no bone outcomes were reported and the evidence was low quality.Vitamin D supplementation for sickle cell disease.
- In nine trials of postmenopausal women without osteoporosis, vitamin D raised blood vitamin D and improved some bone remodeling measures, but only one study found fewer fractures, so a fracture benefit could not be confirmed.Supplementation of vitamin D isolated or calcium-associated with bone remodeling and fracture risk in postmenopausal wom…
- In 500 elderly women with Alzheimer disease who all took 1000 IU of vitamin D2 plus calcium, adding risedronate for 18 months raised bone density 4.1% and cut hip fracture risk compared with placebo, but vitamin D itself was not tested alone and the paper was retracted.The prevention of hip fracture with risedronate and ergocalciferol plus calcium supplementation in elderly women with Al…
- Children whose mothers took 1000 IU of vitamin D3 daily during pregnancy had higher whole-body bone mineral content and density at ages 6-7 than children whose mothers took placebo.Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled…
- In 242 elderly men with Parkinson disease who all took 1000 IU of vitamin D2, adding risedronate for 2 years raised bone density, but vitamin D was not compared against placebo and the paper was retracted.Risedronate and ergocalciferol prevent hip fracture in elderly men with Parkinson disease.
- In Tuscany, Italy, most people who broke a hip from 2011 to 2015 were not taking vitamin D supplements, and only 30-35% were on cholecalciferol one year after the fracture; no bone outcome was measured against a comparison group.The use of cholecalciferol in patients with hip fracture.
- In a 2-year cross-sectional study of 116 pre- and post-menopausal obese and non-obese women, daily vitamin D and calcium intake was low and osteoporosis was less common in obese women, though blood vitamin D levels were within normal range.Dietary Pattern and Bone Health in Pre and Post-menopausal Obese Women.
Review Totals and Summary
Members Only1,420 reviews · 95% positive
Across the two stores, this Thorne Vitamin D-5,000 (NSF Certified for Sport) has 1,420 ratings, and the themes below come from the written reviews that could be read on their pages, which amounted to about five short reviews plus an AI-generated overview that appears on each page. Nothing about other product forms came up, so there was nothing to leave out on that front; this is all about the capsules. The strongest theme is quality and trust. Several reviewers call it a quality product they can trust, and one calls it excellent. Another says they are very satisfied with the vitamins they bought and plan to stay a customer. Short comments such as "Great product" and "Amazing product" also appear, without further detail. The page overviews echo this, saying customers value the product's quality and the brand behind it. Effectiveness and tolerability come up as well. The overviews describe the capsules as highly effective and well tolerated. One long-term user has taken it for years during the winter months and says it works well for keeping a good attitude in bad weather. The overviews likewise say customers credit it with improving mood and energy levels. So mood support, especially when sunlight is scarce, is a recurring idea. On form, customers describe the capsules as small and easy to swallow. The overviews also point to features buyers value: the NSF Certified for Sport status, and the absence of lactose and preservatives. Taste is not mentioned, which fits a capsule. Price and value were not discussed in the summaries. As for who it suits, it seems to appeal to people who want a trusted, tested supplement, including athletes or others who care about the NSF Certified for Sport testing. It also suits people who take vitamin D seasonally in winter, and people dealing with a known low vitamin D level. One reviewer is taking it while being monitored for a vitamin D deficiency and says they will know more after their next checkup. Another is pleased and waiting on that same kind of checkup to see whether the deficiency is being corrected. Those are ongoing situations, not finished results, so they should not be read as proof that it corrects a deficiency. On the negative side, there is essentially nothing to report. None of the written reviews that could be read contains a complaint, including about taste, size, or side effects. The lower star ratings shown in the rating histogram are not explained by any readable text, so the reasons behind any lower scores are unknown. The reviews shown are verified purchases. Overall, the readable feedback is warm and consistent: trust in the brand, small and easy-to-swallow capsules, perceived effectiveness, mood and energy support, and confidence in the certification and clean ingredient list. The written sample is only a handful of comments set against 1,420 ratings, so it indicates tone rather than a complete picture of every buyer's experience.
Biohacker Summary
Members Only8 of 10 recommend it
Vitamin D is the main ingredient here, and nearly the whole panel backs it: most of the ten recommend it or take it themselves, while a few stay neutral. People take it for immune support, brain and mood, bone health, muscle, and general health or longevity, and several lean on it in fall and winter when sun exposure is low. Four panelists take 5,000 IU of vitamin D3 in the morning, one suggests 10,000 IU or more for some goals, and the D3 form is the one mentioned most often. Pairing advice is consistent: take it with dietary fat for better absorption, and add vitamin K2 and magnesium for bone and calcium support. Several advise testing blood levels first, and one says supplementing mainly makes sense if you are deficient, while one warns that the official daily intake is set too low; no one reported stopping it.
See all 10 biohackers →Hide the biohackers
Dr. Eric Berg · Vitamin D · warns
- Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
- Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
- Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
- Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
- Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
- Recommends increasing vitamin D to restore balance and support healthy blood pressure.
- States that a lack of vitamin D can potentially cause achy bones or crashing mood.
- States that vitamin D is intimately involved in the immune system and recommends taking at least 10,000 IUs each day.
- States that taking high doses of vitamin D3 for 14 days can improve mood, sleep, low back pain, skin issues, and blood pressure, as well as act as a natural anti-inflammatory and reduce susceptibility to sickness.
- Mentions that grass-fed liver has vitamin D.
- Mentions that grass-fed liver has vitamin E.
- Dr. Berg states that synthetic vitamin E may be acceptable for short-term use, but long-term use can contribute to oxidative stress.
- Warns against synthetic vitamin E (dl-alpha-tocopherol) for ongoing maintenance, citing a trial where it increased prostate cancer risk and explaining that it can become a free radical and starve out necessary protective forms of vitamin E.
- Recommends taking vitamin E to block the effects of grains.
Dave Asprey · Vitamin D · uses
- Takes Vitamin DAKE from Suppgrade Labs.
- Suggests that vitamin D supports brain health, muscle function, and focus.
- Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
- States that currently, he is only taking vitamin C and vitamin D.
- Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
- Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
- States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
- Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
- Recommends Vitamin D as one of the most important supplements for overall health.
- Recommends Vitamin E as one of the most important supplements for overall health.
- Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
- Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
- Mentions taking vitamin D in the morning, comparing it to the daily dosing of testosterone.
- Includes vitamin K2 as a critical ingredient in Vitamin DAKE, stating that the body needs the right fat soluble vitamins for thousands of reactions.
Siim Land · Vitamin D · recommends
- Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
- Recommends taking Vitamin D with fat for better absorption.
- States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
- Thinks vitamin D has some of the strongest evidence and is worth considering.
- Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
- Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
- Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
- Recommends taking Vitamin D in the morning or at lunch with fat.
- Notes that Boron improves vitamin D.
- Recommends Vitamin D because microglia contain Vitamin D receptors, and Vitamin D helps keep the immune system properly regulated, with low levels associated with greater neuroinflammation and a higher risk of autoimmune conditions.
- Notes that oral vitamin E and C supplementation has been noted to increase the dose of UVB radiation from the sun needed to cause redness of the skin, suggesting increased resilience against sun damage. He also mentions a trial where a combination of slow-release vitamin C and vitamin E decreased the progression of carotid atherosclerosis in men.
- Mentions vitamin E in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
- States that the biggest evidence for multivitamin is that it improves cognition and enhances episodic memory in elderly people, who tend to have worse diets and are more likely to be deficient.
- Created Microvitamin, a supplement that bundled all the supplements he was taking, to help fund his a med trial.
Ben Greenfield · Vitamin E · neutral
- Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
- Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
- Mentions vitamin D as part of a bare-minimum protocol.
- Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
- Has been taking Vitamin D3 K2 for over a decade.
- Notes that sunlight influences more than just vitamin D production.
- Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
- Recommends getting enough vitamin D for blood pressure management.
- Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
- Notes a new study indicating that vitamin E is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
- Recommends Xtendlife's Tocotrienols Vitamin E for cardiovascular, brain, and healthy aging support, noting that research points to tocotrienols over alpha-tocopherol.
- Recommends using hormone building blocks like vitamin D for hormone optimization.
- Notes that vitamin D deficiency is the most common deficiency.
- Recommends whole food vitamin E, explaining that typical supplements only provide alpha-tocopherol, while the whole food complex includes four tocopherols and four tocotrienols, often with selenium at the core.
Dr. Mark Hyman · Vitamin D · recommends
- Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
- Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Notes that vitamin D plays a role in immune function.
- Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
- Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
- States that vitamin D supplementation can help with oxidative stress.
- Mentions vitamin D as a key nutrient for supporting immune function.
- States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
- Notes that rickets, which causes terrible bone deformities, is caused by vitamin D deficiency.
- Notes that vitamin D is an important nutrient for brain performance and aging, and that many people have gaps in these nutrients.
- Notes that patients who were very malnourished had extremely low vitamin E.
- Lists Vitamin E as important for cell protection and anti-aging.
- Recommends avoiding Vitamin E for at least a week before surgery because it can thin the blood.
- Notes that Vitamin E levels are low in Parkinson's patients.
Thomas DeLauer · Vitamin D · uses
- Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
- Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
- Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
- Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
- Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
- Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
- Recommends getting vitamin D, suggesting it can be obtained while walking.
- States that vitamin D is best obtained from the sun, but getting it from food definitely helps, and notes its role as a hormone influencing many cells.
- Recommends D3, suggesting a dose of 2000-4000 IU, and notes that MK-7 slowed bone loss over three years.
- Mentions a causal link found between vitamin E and waking up in the middle of the night.
- Recommends vitamin D, especially for Hashimoto's, explaining that it drives T reg expansion to suppress autoimmune responses that attack the thyroid, and notes that vitamin D and selenium deficiencies often co-occur.
- Recommends using a multivitamin to ensure adequate micronutrient intake, especially when wholesome food is less available.
- Advises checking multivitamins because many contain 100, 200, or 300% of the daily value of selenium, which can contribute to excessive intake.
- Recommends vitamin E for protecting skin cell membranes, reducing oxidative stress, and preventing lipid damage, especially for those with high stress and low dietary intake.
Bryan Johnson · Vitamin D · uses
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
- Takes 5000 IU of Vitamin D3 in the morning for longevity.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Recommends adequate Vitamin E for hair health, noting it is in the Blueprint stack.
- Uses Vitamin E at 10 IU/ML in his custom topical hair formulation.
Dr. Rhonda Patrick · Vitamin D · neutral
- Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
- Mentions that vitamin D also plays a role in maintaining muscle mass.
- Recommends ensuring adequate vitamin D intake for men's sperm health.
- Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
- Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
- Recommends Vitamin D, explaining that it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity.
- Combining omega-3s with vitamin D and exercise has an additive effect, translating to ~3 months of slowed biological aging.
- The effect got stronger when omega-3 was combined with vitamin D and resistance training, with the full stack delaying phenotypic aging by about 3.8 months.
- Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
- Notes that ~60% of Americans are low in vitamin E.
- Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
Andrew Huberman · Vitamin D · neutral
- Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
- Takes 5000 IU of Vitamin D3 in the morning.
- He takes 5,000 IU of Vitamin D3 in the morning for overall health.
- Takes 5000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 every day for longevity.
- Takes a multivitamin every day for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Warns that high-dose supplementation of Vitamin E, when given to lung cancer patients, led to worse outcomes than control subjects, highlighting that it's not the same as ingesting it in food.
- Recommends Vitamin E as part of the AREDS2 supplementation for slowing the progression of dry macular degeneration.
- Mentions evidence suggesting that a combination of vitamin C and vitamin E can blunt hypertrophic adaptations because they are anti-inflammatory antioxidants.
Peter Attia · Vitamin D · uses
- Lists vitamin D as one of her staple supplements.
- Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
- States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
- Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
- In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
- Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
- Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
- Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
- Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
- Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
- Notes that there are some downsides to Vitamin E, including cardiovascular longitudinal risk and prostate cancer, and that discussions are needed with patients, especially those with diabetes or cirrhosis, due to studies indicating increased all-cause mortality depending on the dose.
- Peter Attia, involved in the American Urological Association Peyronie's guidelines, stated that vitamin E is not indicated for Peyronie's disease and should not be given.
- States that American Urological Association guidelines advise against giving vitamin E for Peyronie's disease as it is not indicated.
- Suggests that taking vitamin E would almost assuredly not be required if one eats a balanced diet.
RAL Summary
Members OnlyTier 4 for Bone Health
The studies given are mixed rather than showing vitamin D does not work: one review found fewer hip and other fractures at 700 to 800 units a day and one trial found denser bones in children, while other reviews found no fracture benefit, and two studies tested calcium combinations or vitamin D-like drugs rather than this vitamin alone. So it is graded Tier 4, as the studies disagree.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 3 of the 13 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Skeletal system, Endocrine system
Combine with: For bone health, pair vitamin D3 with vitamin K2 (MK-7) to help direct calcium into bone rather than soft tissue, magnesium (glycinate or citrate) which is needed to activate vitamin D, and dietary or supplemental calcium if intake is low. Take it with a meal containing fat for better absorption. If your real goal is blood sugar support, consider adding evidence-backed ingredients such as berberine, chromium picolinate, alpha-lipoic acid, or Ceylon cinnamon, and consider omega-3 fish oil for cardiovascular support. Check your 25-hydroxyvitamin D level with your clinician to avoid excess dosing, and consult a healthcare provider before combining supplements with meds.
Possible side effects: No major side effects reported. The dose is above the daily recommended limit, so members may choose to take less.
Supplement Facts
Vitamin D 125 mcg
| Vitamin D | 125 mcg |
Other ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide, Vitamin E Succinate.
Directions: Take 1 capsule daily or as recommended by your health-care practitioner.
Label source: Reverseagelab · Report a label change
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Our articles on this subject
- Peter Attia's Supplement List: What He Takes and What the Trials SayArticle · Sep 20, 2026
Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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