Thorne Vitamin D3 Review
THORNE Vitamin D3 with a Metered Dispenser is a liquid vitamin D supplement marketed as vegan, offering plant-based vitamin D3 that the page says supports healthy teeth and bones by enhancing the absorption of calcium, and supports immune function and cardiovascular health. The page lists the product at 4,000 IU of vitamin D per serving, packaged as 1 fluid ounce (30 mL) with 30 servings in the container. The product is presented as a liquid with a bulb-dropper top that measures doses of both 2,000 and 4,000 IUs of vitamin D, and the page states that the drops can be mixed with food or beverages, which the seller describes as enabling customizable supplementation. The page explains that vitamin D3, which it identifies as cholecalciferol, is described as more potent and better absorbed than vitamin D2, also called ergocalciferol, and says research shows vitamin D3 is more effective at raising overall vitamin D levels. The page makes these structure and function style statements, which are marked with an asterisk on the page. The brand highlights its testing process, saying its laboratories conduct four rounds of testing on every product, starting with analysis of the purity of raw materials and extending to confirming the shelf life of finished formulas. Thorne is described on the page as trusted by more than 100 professional sports teams. The page also states that Thorne is the number one most recommended clinical brand by consumers and health-care practitioners, based on a 2026 independent survey of US supplement consumers and health-care practitioners. The listing is sold by Pattern and shipped by Walmart, with a single listed price of 24.00 US dollars, a one-time purchase option, and a subscription option. Shipping is listed as free with an estimated arrival date shown on the page. The Walmart page includes sections titled About this item, Product details, Specifications, Indications, Directions, Warranty, and Ingredients, but the text of those sections is not included in the scraped content, so details such as the full ingredient list, directions for use, and warranty terms cannot be confirmed from this page. Free holiday returns are also mentioned on the listing.
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Study, Trial or Testing Result Summary
Members OnlyHuman studies
No ingredient findings were provided for this product and this goal, so no study results on bone health can be reported here. The label as recorded lists only medium chain triglyceride oil, which is the carrier oil the drops are made in. It does not show the amount of vitamin D3 per serving. The store listing names the same oil plus mixed tocopherols, a form of vitamin E commonly used to keep oils fresh. Neither the oil nor the tocopherols were linked to any human study on bone health in the material given. Without the vitamin D3 dose on the label and without studies tied to this goal, members cannot judge from this record whether the product contains a studied amount of its main ingredient. Buyer ratings are very positive, but ratings alone do not show an effect on bone health. The written comments that could be read describe ease of use and personal impressions, such as hair and nail growth or mood in winter, rather than bone outcomes. Anyone taking it for bone health should check the vitamin D3 amount on the bottle and discuss blood levels with a doctor. Animal and cell studies are never counted.
Review Totals and Summary
Members Only719 reviews · 100% positive
Overall, Thorne Vitamin D3 liquid drops get a very positive response, with about 10 ratings across the stores and every starred review giving 4 or 5. The sample is small, and the store summary notes that the written praise on the Walmart page comes from reviews labeled as incentivized, so the enthusiasm should be read with that in mind. No other forms (gummies, capsules, powder) appear here, so nothing has been left out on that count. **What buyers say it did for them:** The most detailed report credits the drops with faster, thicker hair growth and very hard nails that grow quickly: "my hair grows so fast and has gotten thicker." One long-term user takes it through winter and says it works "on keeping a good attitude in bad weather." Others have not yet seen results. One is waiting for a checkup to see whether it corrects a vitamin D deficiency, and another says they are "still waiting on results." These are personal accounts, not confirmed outcomes. **What buyers complain about:** There are essentially no complaints. The only practical issue is that the drip can be too slow. One reviewer's fix is to tuck the bottle under an arm for a few minutes to warm it, after which the drops come out more quickly. The store summary notes that no review raises complaints about price, packaging, or side effects. **Taste, smell, and form:** Reviewers like the dropper format. One says it is "easy to use and measure," and another says it is "Easy to take and easy to swallow." A third welcomes "no more huge pills." On taste, one buyer calls it "pretty much tasteless" and contrasts it with a previous brand of drops they found "yucky." Smell is not mentioned. **Value for money:** Price is not discussed in the reviews or the store summary, so there is nothing to report on value either way. **Who it seems to suit and who it did not:** It seems to suit people who dislike swallowing large pills and want a dose they can measure with a dropper. It also appeals to buyers who trust the Thorne brand: "A quality product you can trust." Several came to it on professional advice. One reviewer's cardiologist recommended it, and another says a doctor prescribed it for their son to support his immune system. It has also been used for a suspected vitamin D deficiency and as a seasonal winter supplement. No reviewer says it did not suit them, though a few have not yet judged its effect. Anyone bothered by slow dropper flow may need the warming trick.
Biohacker Summary
Members Only8 of 10 recommend it
Vitamin D is labeled a smaller ingredient in this product in every statement, yet the whole panel of ten spoke about it, and almost all of them recommend it or use it. Their reasons include immune support, brain and mood, bone health, muscle, and general health or longevity, and several say to get blood levels tested, with targets ranging from 40 up to 100 nanograms per milliliter. Doses vary widely: four panelists take or cite 5,000 IU of D3 in the morning, while one recommends at least 10,000 IU daily in winter and another names about 8,895 IU as the real need. Many pair it with vitamin K2, magnesium, or dietary fat for absorption, and one takes it in fall and winter when sun is limited. The main caution is from one panelist who says there is no point supplementing unless you are deficient, though he adds that most people probably are; no one reported stopping. Vitamin E is also a smaller ingredient in this product, and the two panelists who mentioned it gave daily use for kids and a neutral note on bleeding.
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Dr. Eric Berg · Vitamin D · warns
- Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
- Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
- Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
- Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
- Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
- Recommends increasing vitamin D to restore balance and support healthy blood pressure.
- States that a lack of vitamin D can potentially cause achy bones or crashing mood.
- States that vitamin D is intimately involved in the immune system and recommends taking at least 10,000 IUs each day.
- States that taking high doses of vitamin D3 for 14 days can improve mood, sleep, low back pain, skin issues, and blood pressure, as well as act as a natural anti-inflammatory and reduce susceptibility to sickness.
- Mentions that grass-fed liver has vitamin D.
- Mentions that grass-fed liver has vitamin E.
- Dr. Berg states that synthetic vitamin E may be acceptable for short-term use, but long-term use can contribute to oxidative stress.
- Warns against synthetic vitamin E (dl-alpha-tocopherol) for ongoing maintenance, citing a trial where it increased prostate cancer risk and explaining that it can become a free radical and starve out necessary protective forms of vitamin E.
- Recommends taking vitamin E to block the effects of grains.
Dave Asprey · Vitamin D · uses
- Takes Vitamin DAKE from Suppgrade Labs.
- Suggests that vitamin D supports brain health, muscle function, and focus.
- Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
- States that currently, he is only taking vitamin C and vitamin D.
- Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
- Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
- States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
- Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
- Recommends Vitamin D as one of the most important supplements for overall health.
- Recommends Vitamin E as one of the most important supplements for overall health.
- Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
- Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
- Mentions taking vitamin D in the morning, comparing it to the daily dosing of testosterone.
- Includes vitamin K2 as a critical ingredient in Vitamin DAKE, stating that the body needs the right fat soluble vitamins for thousands of reactions.
Siim Land · Vitamin D · recommends
- Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
- Recommends taking Vitamin D with fat for better absorption.
- States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
- Thinks vitamin D has some of the strongest evidence and is worth considering.
- Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
- Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
- Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
- Recommends taking Vitamin D in the morning or at lunch with fat.
- Notes that Boron improves vitamin D.
- Recommends Vitamin D because microglia contain Vitamin D receptors, and Vitamin D helps keep the immune system properly regulated, with low levels associated with greater neuroinflammation and a higher risk of autoimmune conditions.
- Notes that oral vitamin E and C supplementation has been noted to increase the dose of UVB radiation from the sun needed to cause redness of the skin, suggesting increased resilience against sun damage. He also mentions a trial where a combination of slow-release vitamin C and vitamin E decreased the progression of carotid atherosclerosis in men.
- Mentions vitamin E in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
- States that the biggest evidence for multivitamin is that it improves cognition and enhances episodic memory in elderly people, who tend to have worse diets and are more likely to be deficient.
- Created Microvitamin, a supplement that bundled all the supplements he was taking, to help fund his a med trial.
Ben Greenfield · Vitamin E · neutral
- Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
- Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
- Mentions vitamin D as part of a bare-minimum protocol.
- Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
- Has been taking Vitamin D3 K2 for over a decade.
- Notes that sunlight influences more than just vitamin D production.
- Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
- Recommends getting enough vitamin D for blood pressure management.
- Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
- Notes a new study indicating that vitamin E is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
- Recommends Xtendlife's Tocotrienols Vitamin E for cardiovascular, brain, and healthy aging support, noting that research points to tocotrienols over alpha-tocopherol.
- Recommends using hormone building blocks like vitamin D for hormone optimization.
- Notes that vitamin D deficiency is the most common deficiency.
- Recommends whole food vitamin E, explaining that typical supplements only provide alpha-tocopherol, while the whole food complex includes four tocopherols and four tocotrienols, often with selenium at the core.
Dr. Mark Hyman · Vitamin D · recommends
- Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
- Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Notes that vitamin D plays a role in immune function.
- Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
- Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
- States that vitamin D supplementation can help with oxidative stress.
- Mentions vitamin D as a key nutrient for supporting immune function.
- States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
- Notes that rickets, which causes terrible bone deformities, is caused by vitamin D deficiency.
- Notes that vitamin D is an important nutrient for brain performance and aging, and that many people have gaps in these nutrients.
- Notes that patients who were very malnourished had extremely low vitamin E.
- Lists Vitamin E as important for cell protection and anti-aging.
- Recommends avoiding Vitamin E for at least a week before surgery because it can thin the blood.
- Notes that Vitamin E levels are low in Parkinson's patients.
Thomas DeLauer · Vitamin D · uses
- Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
- Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
- Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
- Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
- Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
- Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
- Recommends getting vitamin D, suggesting it can be obtained while walking.
- States that vitamin D is best obtained from the sun, but getting it from food definitely helps, and notes its role as a hormone influencing many cells.
- Recommends D3, suggesting a dose of 2000-4000 IU, and notes that MK-7 slowed bone loss over three years.
- Mentions a causal link found between vitamin E and waking up in the middle of the night.
- Recommends vitamin D, especially for Hashimoto's, explaining that it drives T reg expansion to suppress autoimmune responses that attack the thyroid, and notes that vitamin D and selenium deficiencies often co-occur.
- Recommends using a multivitamin to ensure adequate micronutrient intake, especially when wholesome food is less available.
- Advises checking multivitamins because many contain 100, 200, or 300% of the daily value of selenium, which can contribute to excessive intake.
- Recommends vitamin E for protecting skin cell membranes, reducing oxidative stress, and preventing lipid damage, especially for those with high stress and low dietary intake.
Bryan Johnson · Vitamin D · uses
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
- Takes 5000 IU of Vitamin D3 in the morning for longevity.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Recommends adequate Vitamin E for hair health, noting it is in the Blueprint stack.
- Uses Vitamin E at 10 IU/ML in his custom topical hair formulation.
Dr. Rhonda Patrick · Vitamin D · neutral
- Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
- Mentions that vitamin D also plays a role in maintaining muscle mass.
- Recommends ensuring adequate vitamin D intake for men's sperm health.
- Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
- Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
- Recommends Vitamin D, explaining that it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity.
- Combining omega-3s with vitamin D and exercise has an additive effect, translating to ~3 months of slowed biological aging.
- The effect got stronger when omega-3 was combined with vitamin D and resistance training, with the full stack delaying phenotypic aging by about 3.8 months.
- Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
- Notes that ~60% of Americans are low in vitamin E.
- Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
Andrew Huberman · Vitamin D · neutral
- Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
- Takes 5000 IU of Vitamin D3 in the morning.
- He takes 5,000 IU of Vitamin D3 in the morning for overall health.
- Takes 5000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 every day for longevity.
- Takes a multivitamin every day for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Warns that high-dose supplementation of Vitamin E, when given to lung cancer patients, led to worse outcomes than control subjects, highlighting that it's not the same as ingesting it in food.
- Recommends Vitamin E as part of the AREDS2 supplementation for slowing the progression of dry macular degeneration.
- Mentions evidence suggesting that a combination of vitamin C and vitamin E can blunt hypertrophic adaptations because they are anti-inflammatory antioxidants.
Peter Attia · Vitamin D · uses
- Lists vitamin D as one of her staple supplements.
- Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
- States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
- Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
- In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
- Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
- Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
- Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
- Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
- Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
- Notes that there are some downsides to Vitamin E, including cardiovascular longitudinal risk and prostate cancer, and that discussions are needed with patients, especially those with diabetes or cirrhosis, due to studies indicating increased all-cause mortality depending on the dose.
- Discusses research where medium chain triglycerides were used during high-intensity exercise to spare glycogen and improve performance, but almost everyone experienced diarrhea.
- Peter Attia, involved in the American Urological Association Peyronie's guidelines, stated that vitamin E is not indicated for Peyronie's disease and should not be given.
- States that American Urological Association guidelines advise against giving vitamin E for Peyronie's disease as it is not indicated.
RAL Summary
Members OnlyTier 4 for Bone Health
Tier 3 requires some study support, but no human studies were given for this goal, and the label lists only the carrier oil, not vitamin D3 itself, so the evidence is thin and supports tier 4. So it is graded Tier 4, lower than the rules alone gave.
- Emerging: not enough evidence to rank higher yet.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Skeletal system
Combine with: For its primary bone health role, pair vitamin D3 with vitamin K2 (MK-7) to help direct calcium into bone rather than soft tissue, and with magnesium (glycinate or citrate), which is needed to activate vitamin D. Calcium from diet or a supplement can be added if intake is low. If the goal is blood sugar support, stack it with evidence-backed options such as berberine, chromium picolinate, alpha-lipoic acid, or Ceylon cinnamon, and consider omega-3 fish oil for cardiovascular and triglyceride support. Check 25-hydroxyvitamin D levels to guide dosing, and consult a healthcare provider, especially if taking diabetes or heart medications.
Possible side effects: No major side effects reported.
Supplement Facts
Vitamin D 100 mcg
| Calories | 10 | |
| Total Fat | 1 g | |
| Saturated Fat | 1 g | |
| Vitamin D | 100 mcg |
Other ingredients: Medium Chain Triglyceride Oil, Mixed Tocopherols.
Directions: Take ½-1 dropperful daily or as recommended by your health-care practitioner.
Label source: Reverseagelab · Report a label change
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Our articles on this subject
- Peter Attia's Supplement List: What He Takes and What the Trials SayArticle · Sep 20, 2026
Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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