Vitality For Life Unforgettables Review

Unforgettables by Vitality For Life is listed in the Dietary Supplement Label Database under DSLD ID 334759 as a Botanical with Nutrients product in tablet form. The label lists a net content of 30 tablets, with a serving size of one tablet taken once daily with food, giving 30 servings per container. The market status is shown as On Market, and the label was entered into the database on 24 July 2025. The product is classified with an intended target group of adults aged 18 to 50 years, and it is labeled as kosher and gluten free. The Supplement Facts panel lists Calcium at 150 mg (12% Daily Value) as calcium carbonate, a proprietary blend totaling 515 mg that contains bacopa leaf extract and ginkgo leaf extract, and phosphatidylserine at 100 mg sourced from sunflower seed extract. Daily Values are not established for the proprietary blend or the phosphatidylserine. The other ingredients listed are microcrystalline cellulose, cellulose gum, silicon dioxide, stearic acid, magnesium stearate, hydroxypropyl methylcellulose, calcium carbonate, polyethylene glycol, hydroxypropyl cellulose, and carnauba wax. The label statements describe the formula as supporting optimal brain health and neurotransmission support, with a proprietary blend of bacopa and ginkgo biloba intended to help maintain a healthy level of neurotransmitter activity. The phosphatidylserine content is described as supporting faster processing and recall of information. The label also says the product helps safeguard against age-related memory loss and promotes nerve health while guarding against normal nerve decline. The packaging carries a tamper-evident inner seal, with a note that the product should not be accepted if the seal is broken. Storage guidance is to keep it in a cool, dry, dark place. Precautions advise consulting a physician before use if pregnant, planning to become pregnant, nursing, under a doctor's care, taking any medications, or giving it to children under 18, and the product should be kept out of reach of children. The FDA disclaimer states that these statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent any disease. The FDA statement of identity is dietary supplement. The manufacturer is listed as Vitality for Life, with information sourced from NIH in July 2025. The page includes a label image linked to the NIH PDF, along with export options in CSV, XLSX, and JSON. No price, customer reviews, or star ratings are shown on this page.

Product Focus: Focus and MemoryAlso covers:Brain
Tier ⓘ
Tier 4 · Rank 13
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 13 within Tier 4 for Focus and Memory; 33 of 40 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
35 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
– no stars shown, 396 reviews
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only15 human studies · 9 improved
15 human studies9 improved2 no effect9,007 people studied

The best supported ingredient here is phosphatidylserine, at a full 100 mg a day. In 51 people with probable Alzheimer's disease, 300 mg a day for 12 weeks improved several thinking measures, most clearly in milder cases [1]. In 190 older adults with mild memory decline, a combination giving about 63 mg a day for 12 months improved arithmetic and short-term memory [2]. A magnesium and phosphatidylserine formula improved memory scores in 109 healthy adults within 30 days [3]. In 36 children with attention problems, 200 mg a day improved attention and short-term memory [4], though a pooled analysis of three trials in children found less inattention but no clear change in overall symptoms, with low quality evidence [5]. Calcium at 150 mg is unlikely to help: a large trial of 4,143 older women taking 1,000 mg of calcium with vitamin D for about 7.8 years found no change in dementia risk or thinking scores [6], and the one trial that reported a thinking gain tested magnesium, not calcium [7]. Bacopa and ginkgo are hidden in a proprietary blend with no amounts shown, and no study findings for them were given here. Animal and cell studies are never counted.

See all 15 studies →Hide the studies

Review Totals and Summary

Members Only396 reviews
396 reviews · Melaleuca 396

Buyers of the Vitality For Life Unforgettables tablets are mostly positive. They credit it with more energy and sharper memory and thinking, though a couple of people saw no benefit or felt unwell on it. None of the reviews mention other forms of the product, so nothing had to be left out. **What buyers say it did for them:** Energy and mental sharpness come up most. One person says, "Definitely feel the difference I have more energy," and another reports being "more alert, more energetic, healthier looking skin, shinier hair." Many others talk about memory and thinking: "I come up with names a lot quicker!" and "It helps me think." One reviewer says it made "a very big difference to my cognitive abilities," but also takes a mushroom supplement with Lion's Mane, so the credit is shared. Another says it "helped him immensely" after her husband's stroke. Long-term users are loyal: "I've been taking these vitamins for over 15 years now, they really work!" **What they complain about:** Complaints are few. One buyer felt sick: "It made me nauseous each time I took it." Another saw no advantage over other products: "Same as any other." One person who has taken it for only two weeks says they believe it is helping but cannot yet be sure. **Taste, smell, pill size or form:** The reviews say nothing about taste, smell or the size of the tablets. The nearest comment is about how well the body takes them in: "Vitamins and minerals were easily digested and absorbed." Another buyer calls it "so readily absorbed." These are the buyers' own impressions rather than anything shown in the reviews. **Value for money:** Price is hardly discussed. One reviewer accepts paying more because they understand it "dissolves better" and is absorbed better "than cheaper brands," and they report more energy as a result. Another found nothing superior to ordinary vitamins, which suggests the extra cost is not worthwhile for everyone. **Who it seems to suit and who it did not:** Reviewers who like it include older adults who want help with memory and speed of thought. One is 79 and says "I NEED this supplement daily." A woman in her forties says it gives her the energy she needs, and a daughter says her mother feels it helps her cognitively. A stroke survivor's spouse also found it helpful. It suited people looking for a daily multivitamin with a mental-focus angle, and those who like to stay on one product for years. It did not suit the buyer who became nauseous, or the one who wanted something clearly better than a standard multivitamin. **Bottom line:** If you want a multivitamin aimed at energy and memory, most reviewers were pleased. Expect individual results to vary, and note that the reviews do not cover taste, pill size or price in any detail.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

On calcium, the main ingredient, the panel is split and leans cautious about supplements. Three of them recommend it for bone health, with one suggesting 1,000 to 1,200 milligrams a day from calcium carbonate or calcium citrate, and another suggesting calcium citrate with a high oxalate meal. Several others prefer food such as sardines, dairy and leafy greens, and four warn that supplemental calcium may harm arteries or cause kidney stones, with one noting it does not build bones on its own. One advises stopping calcium supplements and another tries to avoid multivitamins with much calcium. Those who give pairing advice say to take it with vitamins D, A and K2, keep it at about two parts calcium to one part magnesium, and not take it together with magnesium. Phosphatidylserine is a smaller ingredient in this product, and several panelists recommend or use it for cortisol, sleep or memory.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Calcium · warns
    • 25 Oct 2026 · warns · YouTube ↗
      Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
    • 10 Oct 2026 · warns · Podcast ↗
      Dr. Berg includes calcium carbonate among the synthetic supplements to avoid.
    • 8 Oct 2026 · Phosphatidylserine · recommends · YouTube ↗
      Recommends phosphatidylserine, stating that 400 to 800 milligrams over several months can greatly help upgrade cortisol receptor sensitivity and support the nervous system.
    • 3 Oct 2026 · warns · YouTube ↗
      Warns against calcium carbonate, also known as limestone, stating that while it lowered hip fractures in a study, it also increased kidney stones and is not good for arteries, requiring the body to work hard to use it.
    • 27 Sep 2026 · neutral · X ↗
      Notes that tannins in tea bind calcium, blocking its absorption.
    • 10 Sep 2026 · neutral · Facebook ↗
      Indicates that horizontal thin white lines near the base of the nails are indicative of low calcium.
    • 4 Sep 2026 · warns · Facebook ↗
      Warns that calcium carbonate can build up in the arteries and kidneys and increase the risk of a heart attack.
    • 3 Sep 2026 · neutral · Facebook ↗
      Dr. Berg mentions that fermented dairy contains vital nutrients, including calcium.
    • 3 Sep 2026 · neutral · Instagram ↗
      States that calcium and magnesium are intrinsically linked and work in combination with vitamin D to support the body's calcium balance.
    • 17 Aug 2026 · neutral · Facebook ↗
      Explains that calcium triggers muscle contraction, while magnesium is needed to relax the muscles afterward.
    • 9 Aug 2026 · warns · YouTube ↗
      Warns that too much calcium can cause high blood pressure by causing arterial contraction.
  • Siim Land · Calcium · neutral
    • 30 Sep 2026 · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 14 Feb 2026 · recommends · TikTok ↗
      Recommends a high calcium intake for bone health.
    • 28 Dec 2025 · warns · YouTube ↗
      Places calcium supplementation in the 'bad tier' due to its association with increased cardiovascular events, recommending dairy or bones as easier ways to get calcium, though it can be useful for postmenopausal women with low bone density.
    • 6 Oct 2025 · neutral · YouTube ↗
      Mentions that eating enough calcium matters for bone density, but states that it alone won't transform bone density.
    • 8 Sep 2025 · warns · TikTok ↗
      Warns that calcium is linked to a higher risk of heart disease, though people with low calcium status and intake can take it safely.
    • 8 Sep 2025 · warns · YouTube ↗
      Warns that calcium supplements increase the risk of heart disease by raising blood calcium levels too high, leading to hypercalcemia and more calcium being stored in the arteries, and also increase the risk of arrhythmias.
    • 16 Aug 2025 · warns · YouTube ↗
      Warns against calcium supplementation for most people due to its association with increased cardiovascular events, but notes it can be useful for postmenopausal women with low bone density who don't consume dairy.
    • 16 Aug 2025 · neutral · Podcast ↗
      Discusses Calcium as a supplement.
    • 14 Jul 2025 · recommends · YouTube ↗
      Recommends consuming calcium from dairy, tofu, leafy greens, and bones, as it is a key nutrient required for ATP synthase in mitochondrial energy production.
    • 15 Mar 2024 · Phosphatidylserine · recommends · YouTube ↗
      Mentions that Phosphatidylserine comes up as a recommendation because of its effect on cortisol.
  • Thomas DeLauer · Calcium · neutral
    • 18 Sep 2026 · neutral · Facebook ↗
      Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
    • 12 Aug 2026 · recommends · YouTube ↗
      Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
    • 30 Jun 2026 · neutral · YouTube ↗
      Explains that eating sardines with their soft bones provides a serious hit of calcium, which is a perfect combination for bones and may contribute to satiety.
    • 19 Jun 2026 · neutral · YouTube ↗
      Mentions that magnesium and calcium should not be taken together as they cancel each other out.
    • 13 Jun 2026 · warns · YouTube ↗
      Tries to get multivitamins without calcium or with a low amount, as he believes supplemental calcium impacts the absorption of other vitamins and minerals and is not as beneficial as hyped. He cautions against it for most people due to the risk of coronary artery calcification.
    • 12 Jun 2026 · recommends · YouTube ↗
      Recommends getting calcium from dairy sources like milk, yogurt, kefir, and cheese in the morning to support neurotransmitter synchronization crucial for deep and REM sleep, noting that low dietary calcium is linked to insomnia.
    • 10 Jun 2026 · Phosphatidylserine · recommends · YouTube ↗
      Recommends phosphatidylserine as a runner-up for stress and cortisol reduction, explaining it directly blunts the cortisol response, especially post-exercise, and helps regulate the hypothalamic-pituitary-adrenal axis.
    • 20 May 2026 · warns · YouTube ↗
      Warns that calcium competes with magnesium for the same absorption channels, advising to separate magnesium intake from calcium supplements or dairy by at least an hour or two.
    • 2 May 2026 · recommends · YouTube ↗
      Recommends providing the body with adequate dietary calcium, not a calcium supplement, to ensure a clean, strong spark for efficient insulin release.
    • 10 Apr 2026 · warns · YouTube ↗
      Warns that calcium and magnesium should not be taken together as they cancel each other out, though some products use delayed absorption to mitigate this.
    • 22 Mar 2026 · warns · YouTube ↗
      Warns that most people consume too much calcium relative to magnesium, which can disrupt the balance needed for proper bodily function, comparing it to an electrical circuit.
    • 21 Mar 2026 · Phosphatidylserine · recommends · YouTube ↗
      Recommends 400 mg of phosphatidylserine daily, noting that studies show it normalizes the HPA axis and cortisol response in chronically stressed individuals, addressing cortisol resistance.
    • 24 Nov 2025 · Phosphatidylserine · recommends · YouTube ↗
      Recommends 100 to 300 mg of phosphatidylserine as an 'emergency switch' to blunt cortisol on highly stressful days, noting that it normalizes the cortisol response to stress but should not be used consistently.
    • 7 Nov 2025 · Phosphatidylserine · recommends · YouTube ↗
      Recommends 100 to 300 milligrams of Phosphatidylserine as a temporary break on cortisol, helping to calm the body and blunt cortisol rhythms during stressful days.
  • Dr. Mark Hyman · Calcium · recommends
    • 20 Aug 2026 · recommends · YouTube ↗
      Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
    • 17 Jun 2026 · neutral · YouTube ↗
      States that green leafy vegetables are great sources of calcium.
    • 3 Nov 2025 · neutral · Podcast ↗
      Notes that calcium needs are lower than advertised and that stress, soda, and excess sugar can drive calcium loss.
    • 17 Sep 2025 · warns · YouTube ↗
      Does not prescribe calcium supplements at all, teaching people to get it from whole foods instead, because calcium supplements don't work for building bones or preventing fractures, and it's bone quality, not density, that matters.
    • 14 May 2025 · warns · YouTube ↗
      Warns that acid blockers inhibit calcium absorption.
    • 2 Apr 2025 · recommends · YouTube ↗
      Lists calcium as another important nutrient that people can be tested for and measured.
    • 12 Mar 2025 · warns · YouTube ↗
      States that high doses of calcium supplementation in the elderly were not really impacting bone density, as osteopenic patients still became osteoporotic.
    • 5 Feb 2025 · Phosphatidylserine · recommends · YouTube ↗
      Mentions that phosphatidylserine has good data, though not specifically for sleep, and suggests a dose of 300 to 400 milligrams.
    • 29 Nov 2024 · warns · YouTube ↗
      Warns that meds (meds) impair the absorption of calcium, which increases the risk of hip fractures and osteoporosis.
    • 15 Nov 2024 · recommends · YouTube ↗
      Recommends calcium citrate, about 600 milligrams a day, for bone health, noting that much can also be obtained from diet through leafy greens, sesame seeds, tahini, and chia seeds.
    • 27 Sep 2024 · warns · YouTube ↗
      Dr. Hyman notes that while calcium deficiency is not common in terms of blood levels, insufficient intake can lead to osteoporosis as the body pulls calcium from bones. He advises caution with calcium supplementation due to potential heart issues.
    • 31 Jul 2024 · Phosphatidylserine · neutral · YouTube ↗
      Mentions that phosphatidylserine also helps the brain.
    • 3 Apr 2024 · Phosphatidylserine · uses · YouTube ↗
      Took phosphatidylserine, which has been shown to reduce cortisol.
    • 20 Dec 2023 · Phosphatidylserine · neutral · YouTube ↗
      Highlights Phosphatidylserine, a phospholipid integral to brain cell membranes, as being shown to improve memory, learning, and cognitive function.
  • Dr. Rhonda Patrick · Calcium · neutral
    • 29 Jun 2026 · neutral · Facebook ↗
      Mentions that kale delivers calcium, a micronutrient many diets fall short on.
    • 15 May 2026 · Phosphatidylserine · uses · Instagram ↗
      Rhonda takes 300 mg of Phosphatidylserine before bed for sleep.
    • 9 Jan 2026 · neutral · Facebook ↗
      Notes additional gaps in calcium.
    • 3 Jul 2024 · warns · YouTube ↗
      Reports that alcohol use disorder is associated with a 20-50% greater prevalence of Calcium deficiency.
    • 27 Dec 2023 · Phosphatidylserine · uses · YouTube ↗
      Uses phosphatidylserine only when jet lagging or time zone hopping.
    • 9 Oct 2015 · neutral · YouTube ↗
      Around 38% doesn't meet the requirement for calcium.
    • 11 Feb 2015 · uses · YouTube ↗
      Takes a calcium-magnesium pill because he believes people tend to be short of both and that the body cares about the ratio of these similar molecules.
    • 29 Sep 2014 · Phosphatidylserine · recommends · YouTube ↗
      Dr. Patrick notes that krill oil is a great source of phosphatidylserine, which accumulates in mitochondrial and cell membranes and has been shown to decrease in concentration with age, playing a role in neurodegenerative diseases like Parkinson's and Alzheimer's.
    • Date not recorded · recommends · Website ↗
      States that 1,000 milligrams of calcium per day is the recommended intake for bone density, and supplementation is an option if this requirement is not met.
    • Date not recorded · uses · Website ↗
      Takes a calcium, vitamin K2, and vitamin D combination supplement in the morning, providing about 600 mg of calcium and another 1,000 IUs of vitamin D.
    • Date not recorded · neutral · Website ↗
      Dr. Rhonda Patrick discusses calcium needs.
    • Date not recorded · Phosphatidylserine · uses · Website ↗
      He reserves melatonin and phosphatidylserine for jet lag.
    • Date not recorded · Phosphatidylserine · neutral · Website ↗
      She mentions that Peter Attia takes 400 milligrams of phosphatidylserine from Jarrow when he travels.
  • Dave Asprey · Calcium · neutral
    • 16 Jun 2026 · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
    • 12 Jun 2026 · neutral · Instagram ↗
      Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
    • 12 Jun 2026 · neutral · X ↗
      Notes that people take calcium for their bones.
    • 14 May 2026 · warns · YouTube ↗
      Warns that taking calcium without vitamin D, A, and K2 can lead to calcium going into tissues, causing bone spurs and other issues, and recommends a two-to-one ratio of calcium to magnesium.
    • 30 Dec 2025 · recommends · YouTube ↗
      Recommends taking calcium citrate during a high oxalate meal to bind the oxalate in the gut.
    • 21 Oct 2025 · neutral · YouTube ↗
      Notes that people often take calcium for bone health.
    • 5 Aug 2025 · warns · YouTube ↗
      Believes calcium supplements are overrated, as most people need more vitamin K2 and vitamin D instead.
    • 12 Jul 2025 · Phosphatidylserine · recommends · YouTube ↗
      Identifies phosphatidylserine as one of the four best ingredients to reverse brain fog, noting that most people don't get enough of it.
    • 6 May 2025 · Phosphatidylserine · uses · YouTube ↗
      Says that phosphatidylserine or phosphatidylcholine would be life-changing for his mitochondrial lipids.
    • 2 Aug 2024 · recommends · YouTube ↗
      Advises taking iron and calcium separately because they will bind together.
    • 22 Apr 2024 · uses · YouTube ↗
      Takes extra calcium to help deal with the burden when eating chocolate or anything with higher levels of oxalates.
    • 25 Jan 2024 · neutral · YouTube ↗
      Discusses calcium citrate as a counter to oxalate crystals, specifically when consumed through dairy, but questions if it's the primary form of calcium in dairy.
  • Ben Greenfield · Calcium · neutral
    • 9 May 2026 · neutral · YouTube ↗
      Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
    • 6 May 2026 · neutral · X ↗
      Mentions calcium as a common deficiency.
    • 12 Apr 2026 · recommends · Facebook ↗
      Recommends adequate intake of calcium for bone strength.
    • 13 Feb 2026 · uses · YouTube ↗
      Is using calcium chloride mixed with PRP before injecting for the P-shot.
    • 22 Nov 2025 · stopped · YouTube ↗
      Advises people to stop taking calcium supplements as part of the Root Cause Protocol.
    • 21 Aug 2025 · warns · Facebook ↗
      Warns that in high doses, calcium without the right cofactors can raise cardiovascular risk by contributing to arterial calcification instead of bone strength, and may increase the risk of osteoporosis.
    • 3 Apr 2025 · warns · YouTube ↗
      Explains that 10X separates calcium and zinc into different micro beads, releasing them at different rates and locations in the digestive tract to prevent competition and optimize absorption.
    • 26 Dec 2024 · neutral · TikTok ↗
      Covers calcium as a key supplement for kids.
    • 26 Dec 2024 · Phosphatidylserine · recommends · YouTube ↗
      Recommends phosphatidylserine at 100 to 300 milligrams per day for improved memory, attention, and cognitive performance, especially in older people, and also for controlling cortisol when taken at night if stressed.
    • 11 Apr 2024 · warns · YouTube ↗
      Warns of calcium deficiency on a carnivore diet, as there is not an appreciable amount in meat, and recommends eating fish with bones or taking a calcium supplement or bone mineral matrix.
    • 6 Apr 2024 · Phosphatidylserine · recommends · YouTube ↗
      Recommends phosphatidylserine to be taken at night, in doses of 100 to 300 milligrams, to make the pituitary more sensitive to cortisol and lower nighttime cortisol over time.
    • 15 Jun 2023 · Phosphatidylserine · recommends · YouTube ↗
      Recommends phosphatidylserine as a supplement to use whilst traveling.
    • 17 Oct 2020 · warns · YouTube ↗
      Notes that excess calcium intake can contribute to calcium buildup in the arteries.
    • 28 Dec 2019 · Phosphatidylserine · recommends · Podcast ↗
      Recommends phosphatidylserine for modulating cortisol.
  • Peter Attia · Calcium · recommends
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 1 Jun 2026 · Phosphatidylserine · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 6 Jul 2025 · neutral · YouTube ↗
      Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
    • 22 Oct 2024 · recommends · YouTube ↗
      Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
    • 21 Oct 2024 · recommends · YouTube ↗
      Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
    • 26 Feb 2024 · Phosphatidylserine · neutral · YouTube ↗
      Mentions phosphatidylserine as something that can help with sleep in the setting of chronic stress and hypercortisolemia.
    • 24 Oct 2023 · Phosphatidylserine · uses · YouTube ↗
      Occasionally takes 400 mg of Jarrow's phosphatidylserine gel caps for travel, particularly on long flights to overcome significant time zone changes.
    • 23 Oct 2023 · Phosphatidylserine · uses · YouTube ↗
      Occasionally takes Jarrow's phosphatidylserine gel caps, typically 400 mg, for travel to help overcome significant time zone changes.
    • 28 May 2023 · Phosphatidylserine · uses · YouTube ↗
      Uses 400 to 600 milligrams of phosphatidylserine in the evening to suppress cortisol production and facilitate sleep, especially when dealing with jet lag or time zone changes.
    • 18 Jul 2022 · neutral · YouTube ↗
      Notes that bone is 50 to 70 percent mineral, with calcium being the predominant mineral, and virtually all of the body's calcium is contained within bone.
    • 26 Oct 2020 · recommends · YouTube ↗
      Recommends getting about a gram of calcium a day from organic bone meal, which provides calcium hydroxyapatite, the form humans are meant to consume.
    • 12 Jan 2020 · neutral · YouTube ↗
      Suggests that calcium is one of the other signals involved in regulating mitochondrial number, beyond AMPK activation.
    • 9 Jan 2020 · Phosphatidylserine · recommends · YouTube ↗
      Says that slamming yourself with 600 mg of phosphatidylserine really seems to move the needle in terms of both glucose and cortisol response.
    • 7 Jan 2020 · warns · YouTube ↗
      States that in postmenopausal women not on estrogen, calcium and vitamin D have no protective effect against hip fracture because the problem is not the shell of the bone, which is fed by calcium and vitamin D, but the internal girder network.
  • Bryan Johnson · Calcium · recommends
    • 5 Jun 2025 · recommends · YouTube ↗
      Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
    • 12 May 2025 · recommends · YouTube ↗
      Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
    • Date not recorded · recommends · Website ↗
      Recommends prioritizing calcium intake for postmenopausal women to help maintain bone density and reduce the risk of osteoporosis.
    • Date not recorded · uses · Website ↗
      Bryan Johnson takes Calcium daily as part of his Longevity Mix, which supports healthy bones and teeth.
    • Date not recorded · recommends · Source ↗
      Recommends continuing with calcium to support bone health during the follicular phase.
  • Andrew Huberman · Calcium · neutral
    • 6 Mar 2023 · neutral · Podcast ↗
      Discusses "hard water" and the role of magnesium and calcium in cardiovascular health.
    • 16 Apr 2026 · Phosphatidylserine · neutral · YouTube ↗
      Mentions that Phosphatidylserine can enhance learning and memory, and advises taking it late in or immediately after a learning episode for optimal results.
    • 11 Sep 2025 · Phosphatidylserine · recommends · Podcast ↗
      He highlights specific nutrients, including phosphatidylserine, and discusses their recommended doses and dietary sources for brain structure, function and long-term cognitive health.
    • 31 Jul 2025 · Phosphatidylserine · neutral · Podcast ↗
      Mentions Phosphatidylserine in the context of attention effects.
    • 8 May 2024 · Phosphatidylserine · recommends · YouTube ↗
      Recommends Phosphatidylserine, stating it has been reliably demonstrated to tamp down the cortisol response, which can be helpful for insomnia patients whose cortisol spikes as they try to fall asleep.
    • 30 Jan 2023 · Phosphatidylserine · warns · YouTube ↗
      States that Phosphatidylserine (PS) is super effective at reducing cortisol, with 400 mg being more effective than 800 mg in trials, and recommends taking it in the morning if cortisol peaks high then, or at night if cortisol is high at night.
    • 12 Dec 2022 · Phosphatidylserine · recommends · YouTube ↗
      Huberman suggests that acetylcholine precursors like phosphatidylserine are better ways to optimize nicotinic receptor activity.
    • 14 Nov 2022 · Phosphatidylserine · uses · YouTube ↗
      Mentions that Thesis uses high-quality ingredients like phosphatidylserine, which he has discussed before and uses himself.
    • 5 Sep 2022 · Phosphatidylserine · neutral · YouTube ↗
      Mentions Phosphatidylserine as an example of a compound that can be researched on examine.com to find information about its effects.
    • 16 May 2022 · Phosphatidylserine · stopped · YouTube ↗
      Used to take phosphatidylserine before sitting down to learn information or a physical skill, but now realizes this is not optimal for enhancing learning and memory.
    • 11 Apr 2022 · Phosphatidylserine · neutral · YouTube ↗
      Mentions that Thesis uses high-quality ingredients like phosphatidylserine, which he has discussed on the podcast before.
    • Date not recorded · recommends · Website ↗
      Adequate intake of calcium is vital for bone health.

RAL Summary

Members OnlyTier 4 for Focus and Memory

The review summary describes a multivitamin that buyers say they have taken for years and that is 'easily digested and absorbed', while no written reviews of this product could be read and zero reviews were counted, so these reviews are not of this memory formula. Its reviews are set aside, so it is graded on its studies alone. Human studies support Calcium (1 of 3 human studies showed an improvement), but there are not yet enough reviews to confirm it (0).

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 2 of the 15 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system

Combine with: For memory and cognitive support, consider pairing with omega-3 fish oil (DHA/EPA) for neuronal membrane health, phosphatidylserine or citicoline for acetylcholine and cell signaling support, and B-complex vitamins (B6, folate, B12) to help regulate homocysteine. Bacopa monnieri or lion's mane can add support for memory and nerve growth factor. If blood pressure support is the actual goal, use a separate product with magnesium, potassium, CoQ10, or beet root, and consult a healthcare provider, especially if taking antihypertensive medication.

Possible side effects: No major side effects reported in the studies given; no reviews of this product could be read.

Supplement Facts

Calcium 150 mg · Proprietary Blend 515 mg · Phosphatidylserine 100 mg
Supplement Facts
Serving Size 1 Tablet(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Calcium150 mg
Proprietary Blend515 mg†
Phosphatidylserine100 mg†
† Daily Value not established.

Other ingredients: Microcrystalline Cellulose, Cellulose Gum, Silicon Dioxide, Stearic Acid, Magnesium Stearate, Hydroxypropyl Methylcellulose, Calcium Carbonate, Polyethylene Glycol, Hydroxypropyl Cellulose, Carnauba Wax.

Directions: PM Directions: Take one tablet daily with food.

Label source: NIH label database · Report a label change

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Our articles on this subject

Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.