Nature's Sunshine supplements, graded by the human studies
We graded 2 Nature's Sunshine products against the human studies of their ingredients, the dose on each label and what buyers say in their reviews. Each grade belongs to the product and the goal it was graded for: we do not grade how Nature's Sunshine makes, tests or sells its products, and we sell no supplements. Educational, not medical advice.
The Nature's Sunshine products we graded
Members Only2 products, strongest evidence first

What Nature's Sunshine products were graded for
Each goal links to its page, with every product graded for it
| Goal | Nature's Sunshine products |
|---|---|
| Gut Bacteria Balance | 1 |
| Muscle and Strength | 1 |
Read more
Our articles on these goals
- How to Improve Gut Health Naturally: Fiber, Foods and the Probiotic Strains With Human TrialsArticle · Sep 15, 2026
- Probiotics for Gut Health: The Complete GuideArticle · Mar 17, 2026
- Best Probiotic for Bloating: The Strains With Human Trials, and How to Choose OneArticle · Oct 27, 2026
Questions people ask
Members Only
Is Nature's Sunshine a good brand?
We grade products, not brands, and we sell none. Of the 2 Nature's Sunshine products we graded, 1 is Tier 2 (Researched) and 1 is Tier 4 (Emerging). One is top-ranked for the goal it was graded for. Each product's grade, the studies behind it and its label are on its own page.
Which Nature's Sunshine products have the strongest evidence?
By our grades: Probiotic Eleven (Tier 2, graded for gut bacteria balance); IGF-1 (Tier 4, graded for muscle and strength). A product's grade is for the goal it was graded for, at the dose on its label.
How does Reverse Age Lab grade Nature's Sunshine products?
Each product is graded for a goal on the human studies of its ingredients at the dose on its label, what buyers say in their reviews and what our panel of ten biohackers has said. The grade belongs to the product. We do not grade how Nature's Sunshine makes, tests or sells its products, and we are not affiliated with Nature's Sunshine.
Can I take Nature's Sunshine supplements with my meds?
Some supplements can interact with meds. Members have every product checked against the meds in their Health Profile before it joins their protocol.
Educational, not medical advice. Grades come from human studies on PubMed, the dose on each label, store reviews we read ourselves and our biohacker panel, and are updated as new studies arrive. Nature's Sunshine is a trademark of its owner; Reverse Age Lab is not affiliated with it and sells no supplements. How we grade →
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