Alfa Vitamins Collagen C Hydrolysate with Vitamin C Review

Collagen C Hydrolysate 3000 mg with Vitamin C 1000 mg - 30 Packets is an Alfa Vitamins product page for a collagen hydrolysate and vitamin C powder sold in individual packets. The page describes the product as collagen hydrolysate paired with vitamin C, which supports the body's normal collagen formation, and says individual powder packets mix with water or juice. The listed features are hydrolyzed collagen powder, vitamin C that supports collagen formation, and vitamin C that provides antioxidant support. The product details section adds that individual packets make the powder easy to carry and mix. The mixing directions say to pour the contents of one sachet into a glass, add 6 to 8 oz of water or juice, and mix until diluted, and to follow the complete directions on the package. The formula and package table lists collagen hydrolysate at 3,000 mg, vitamin C at 1,000 mg, and a package of 30 packets. The page states that the complete Supplement Facts, serving size, ingredients and warnings are on the package and should be checked there. The page presents two benefit topics. The first is immune function, where it says vitamin C supports the normal function of the immune system. The second is collagen formation, where it says vitamin C helps the body form collagen, a structural protein in skin and connective tissue. A learn-more link points to the NIH vitamin C consumer fact sheet. The precautions say to consult a healthcare professional before use if pregnant, breastfeeding, taking medicines or managing a medical condition, and to keep the product out of reach of children. The page lists the product as in stock and shipping in 1 to 2 business days. The one-time purchase price is $24.00, and a subscription option is shown at $20.40 per delivery with 15% savings, with delivery every 2, 4 or 8 weeks, and shipping and taxes calculated at checkout. Returns are accepted within 30 days for unused items. Alfa Vitamins describes itself as manufacturer-owned, based in Miami, Florida, and trusted since 2000, and states its products are made in its own facility in Miami. The page also says the product is made in the USA and has been quality tested.

Tier ⓘ
Tier 2 · Rank 1
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 1 within Tier 2 for Younger-Looking Skin for Women; 1 of 45 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
84 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
88% of 721
Biohacker Mentions
9 of 10
Cost per month
$18

Study, Trial or Testing Result Summary

Members Only45 human studies · 36 improved
45 human studies36 improved2 no effect8,942 people studied

Collagen hydrolysate is present at 1000 milligrams a day, a dose that worked in studies. A review pooling 26 trials with 1721 people found hydrolyzed collagen improved skin hydration and elasticity more than placebo [1]. Another review of 19 trials with people aged 20 to 70 found about 90 days of use also reduced wrinkles [2]. In 100 women aged 30 to 60, 1650 milligrams daily for 12 weeks improved hydration, wrinkling and elasticity with no side effects [3]. In 114 women aged 45 to 65, 2.5 grams daily for 8 weeks reduced eye wrinkle volume by 20 percent [4]. A caution: a 2025 review of 23 trials found the benefit disappeared in the higher-quality trials and in trials not funded by industry [5]. Vitamin C is included at 50 milligrams, but most of its skin studies used creams or serums applied directly to the skin, such as a 5 percent cream used for 6 months [6] or a cream used around the eyes for 8 weeks [7]. These do not show what a small dose taken by mouth does for wrinkles. Animal and cell studies are never counted.

See all 45 studies →Hide the studies

Review Totals and Summary

Members Only721 reviews · 88% positive
721 reviews · Amazon 704 · Walgreens 13 · Alfavitamins 4
88% positive7% neutral5% negative

The store shows 708 ratings in total, though the only page summarized, Alfavitamins.com, carries just 4 of them, so the themes below come from the four written reviews that could be read on that page. Because so few written reviews were readable, this is a narrow picture and not a broad pattern. What buyers praise: All four reviewers are Verified Buyers, and all four are positive in tone. The reviews are short. Heidi B. says she loves the product and is ready to buy it again. Victoria R. says she loves it and is reordering today. Both point to customers returning for more packets. Sarah M., whose review is titled "Excellent," praises the convenient packets, saying they are easy to take on the go and effective, and she definitely recommends the product. Reyna M. titles her review "Love it!" and writes the same words, which shows general satisfaction without naming a feature, flavour, mixing experience or result. Form and convenience: The packet format is the one specific product attribute mentioned, and portability is the stated benefit. Sarah M.'s comment about taking it on the go is the only concrete detail about how the powder is used. What buyers complain about: Nothing. No reviewer on the page mentions problems with taste, mixing, texture, price, shipping or effectiveness, and there is no negative or mixed written feedback at all. Who it seems to suit: The only hint comes from the packet comment, which suggests people who want a simple, portable way to take collagen while out and about. Beyond that, the reviews don't say who the product suits. Taste and value: Neither is discussed. There is no mention of flavour, how well the powder dissolves, or whether the price feels fair. Results and duration: The reviews give no information on how long people used the product or what results they noticed, apart from Sarah M.'s single word that it is effective. Ratings: The page shows an overall rating of 4.5 based on 4 reviews. It has no star distribution histogram, so the share of positive, neutral and negative ratings can't be worked out from this page. The 708 ratings across the store can't be broken down from what was readable. Scope: Only the powder was considered, and the summary doesn't mention other forms of the product (such as gummies or capsules), so none were included. Any conclusions beyond these four reviews would need more written feedback than the page provides. In short, the readable reviews are enthusiastic, centered on enjoyment, reorder intent, easy on-the-go use and general recommendation, but they offer little detail on taste, texture, price or outcomes.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Collagen gets a mostly favorable reception: three of the ten panelists recommend it, four say they use it, two are neutral, and one has stopped taking it. People take it for skin, joints, connective tissue, muscle and gut care, and the two who cited research on skin elasticity point to 2.5 to 5 grams a day of hydrolyzed collagen peptides for at least eight weeks. Three panelists take about 10 grams in the morning for muscle, and others suggest 15 grams about an hour before a workout, sometimes with vitamin C, or before bed on rest days. One panelist cautions that collagen will not repair a damaged gut wall, one is neutral because collagen has a weaker amino acid makeup than whey for building muscle, and one says lifestyle matters more. Vitamin C is a smaller ingredient in this product, and panelists mostly recommend pairing it with collagen because the body needs it to make collagen.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Collagen · recommends
    • 31 Oct 2026 · recommends · Podcast ↗
      Recommends collagen as it is critical for healthy aging, supporting connective tissues, skin health, and cardiovascular health.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends collagen powder as an alternative to bone broth, to be put in coffee, for its benefits in building connective tissue and providing glycine for sleep.
    • 18 Oct 2026 · neutral · YouTube ↗
      Mentions that grass-fed liver is loaded with collagen.
    • 17 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Highly recommends taking natural food vitamin C, about 500 mg, at the first sign of a cold.
    • 4 Oct 2026 · recommends · YouTube ↗
      States that the body is begging for collagen if one experiences weak ligaments and tendons, joint pain, wrinkles or saggy skin, thin dry fragile hair, brittle slow growing nails, loss of muscle, increased need for longer repair after exercise, and bone loss.
    • 25 Sep 2026 · recommends · Instagram ↗
      Recommends increasing collagen intake because a lack of it can make it harder for the body to repair itself.
    • 20 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends consuming foods high in vitamin C to block the effects of grains.
    • 19 Sep 2026 · neutral · Instagram ↗
      Discusses collagen in relation to changes in joints, skin, hair, nails, and recovery, suggesting these could be signs of needing more collagen.
    • 16 Sep 2026 · uses · YouTube ↗
      Uses one scoop of collagen in their coffee every single morning, noting that the average person needs between 10 and 15 grams minimum daily for benefits like improved joints, nails, hair, gut health, and youthful skin.
    • 16 Sep 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring that collagen supplements come with vitamin C.
  • Siim Land · Collagen · recommends
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends taking Collagen 1 hour before exercise with vitamin C to support joint collagen synthesis.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Collagen for joints, skin and connective tissue, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Collagen as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 21 Sep 2026 · uses · YouTube ↗
      Takes 10 grams of collagen peptides a day, which provides 3 grams of glycine.
    • 8 Sep 2026 · neutral · X ↗
      30% of collagen is glycine, as glycine is every third amino acid in the collagen triple helix.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends marine collagen peptides, citing a study where 5g daily for 12 weeks reduced AGE levels and improved insulin sensitivity.
    • 30 Aug 2026 · neutral · Instagram ↗
      Mentions that taking 15 grams of collagen before bed has been seen to reduce the number of awakenings during the night.
    • 25 Aug 2026 · neutral · X ↗
      Notes that taking 15 grams of collagen before bed has been seen to reduce the number of awakenings during the night.
    • 21 Aug 2026 · neutral · Instagram ↗
      Mentions that glycine makes up one-third of collagen.
    • 17 Aug 2026 · recommends · X ↗
      Recommends taking Collagen one hour before exercise with a vitamin.
  • Thomas DeLauer · Collagen · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Says he takes collagen to take care of his gut.
    • 26 Oct 2026 · recommends · YouTube ↗
      Recommends collagen as a direct dietary source of glycine, suggesting a 15g serving of pure collagen. He advises taking it an hour before a workout for connective tissue benefits or before bed on rest days to help with sleep.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 19 Oct 2026 · recommends · YouTube ↗
      Recommends taking 15 grams of collagen an hour before working out to target connective tissue, as it has been shown to double a marker of collagen synthesis and help rebuild tendons and ligaments that are loaded harder with age.
    • 14 Oct 2026 · uses · YouTube ↗
      Always eats collagen, considering it one of the most underrated things they do for sustainability and recovery, as it supports connective tissue protein synthesis.
    • 9 Oct 2026 · neutral · YouTube ↗
      Mentions that if curling fingers are due to a collagen issue, there's a case for taking collagen peptides to help rebuild connective tissue.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 18 Sep 2026 · Vitamin C · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 8 Sep 2026 · recommends · YouTube ↗
      Recommends taking 15 grams of collagen about 30 minutes before bed, especially on rest days, for its glycine content to aid sleep onset and for connective tissue repair.
    • 6 Sep 2026 · recommends · Instagram ↗
      Recommends opting for foods rich in collagen because modern diets lack it compared to traditional nose-to-tail eating.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends 15 grams of collagen before bed, as it provides 3 grams of glycine and supports connective tissue repair, which peaks during sleep, making it a good way to get glycine for testosterone production.
    • 29 Aug 2026 · Vitamin C · neutral · Instagram ↗
      States that collagen synthesis is vitamin C dependent, in the context of glowing skin.
  • Dave Asprey · Collagen · uses
    • 27 Oct 2026 · uses · YouTube ↗
      States he made collagen into a billion-dollar industry because he needed it for his joints due to Ehlers-Danlos syndrome.
    • 24 Oct 2026 · recommends · Facebook ↗
      Recommends taking collagen for better skin health.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 10 Oct 2026 · warns · YouTube ↗
      Dave Asprey agrees with taking collagen, but warns that using bone broth and collagen to repair a compromised gut wall is like trying to rebuild a collapsed house using nothing but craft glue, as it doesn't provide the rapid high demand energy gut cells need.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 24 Sep 2026 · neutral · Podcast ↗
      Mentions Puori CP1 Pure Collagen as a sponsor, offering a discount on a subscription.
    • 20 Sep 2026 · neutral · YouTube ↗
      Notes that eating collagen can break down into amino acids and create a signaling molecule that tells the body the skin has been injured, leading to thicker skin.
    • 15 Sep 2026 · uses · YouTube ↗
      Explains that One Skin uses collagen amino acids in their formula because they are hygroscopic and help hold water, acting as natural moisturizing factors.
    • 9 Sep 2026 · stopped · YouTube ↗
      Has updated his stance on collagen, now believing there may be some benefit for certain populations in having collagen peptides, especially since they are small and get absorbed.
    • 3 Sep 2026 · neutral · Podcast ↗
      Dave and Jenny walk through the biohacking protocol that helped her son recover from autism, including collagen and hypermobility support.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends increasing collagen intake, specifically about 20 grams of collagen protein, for individuals with hypermobility, but warns against exceeding this amount due to oxalate concerns.
    • 29 Aug 2026 · warns · YouTube ↗
      Dave Asprey warns that collagen supplements have small, short-term effects on skin, mostly from industry-funded studies, and explains that the body breaks it down into amino acids, not directly targeting skin; he suggests taking cheaper protein if protein-deficient.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
    • 25 Jul 2026 · Vitamin C · neutral · Facebook ↗
      Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
  • Ben Greenfield · Collagen · recommends
    • 22 Oct 2026 · recommends · Facebook ↗
      Mentions that two separate meta-analyses found real improvement in skin elasticity when people consumed 2.5 to 5 g of collagen peptides a day for eight weeks.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 22 Oct 2026 · recommends · YouTube ↗
      Recommends 2.5 to 5 grams a day of hydrolyzed collagen peptides for at least 8 weeks to improve skin elasticity and address sagging skin.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 4 Oct 2026 · recommends · Facebook ↗
      Recommends 2.5-5 g/day of hydrolyzed collagen for at least 8 weeks, citing a meta-analysis that found real improvement in skin elasticity.
    • 27 Sep 2026 · recommends · X ↗
      Recommends starting with collagen for body remodeling.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 26 Jul 2026 · recommends · Instagram ↗
      A new meta-analysis reviewed the existing evidence on collagen supplementation and found that collagen peptides may support several aspects of health, including skin aging, osteoarthritis symptoms, fat-free mass, tendon quality, and markers of metabolic health.
    • 12 Jul 2026 · neutral · X ↗
      The latest meta-analysis on collagen backs up collagen benefits for skin aging, osteoarthritis, fat-free mass, tendon quality, and overall metabolic health, with effective doses ranging from 5 to 15g.
    • 9 Jul 2026 · recommends · YouTube ↗
      Recommends collagen for skin repair post-tattoo.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
    • 23 May 2026 · neutral · YouTube ↗
      Notes that collagen is not a complete protein, so while it can be added to things, it should not be relied upon as the sole protein source.
    • 18 Apr 2026 · recommends · YouTube ↗
      Recommends collagen peptides or essential amino acids to support the dermal matrix that anchors hair follicles, considering them important for hair health.
  • Bryan Johnson · Collagen · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 22 Jul 2026 · uses · X ↗
      Consumes collagen peptides at 4:55 am.
    • 1 Jul 2026 · uses · X ↗
      Uses collagen peptides as an ingredient in Nutty Pudding.
    • 4 May 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 2 May 2026 · uses · X ↗
      He takes 10 g of Collagen in the morning for muscle.
    • 21 Apr 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for skin health.
    • 15 Apr 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 14 Apr 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 8 Apr 2026 · uses · X ↗
      Takes 10 grams of collagen in the morning for muscle.
    • 7 Apr 2026 · uses · X ↗
      He takes 10 grams of Collagen in the morning for muscle.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • Date not recorded · Vitamin C · recommends · Website ↗
      Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
  • Dr. Mark Hyman · Collagen · neutral
    • 7 Oct 2026 · neutral · Podcast ↗
      Dr. Hyman mentions collagen supplements in the context of skin aging.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · recommends · YouTube ↗
      Is on 'team collagen' and believes there's enough data to support collagen consumption, noting that it sends signals to help the body build better collagen, though lifestyle factors are more important.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · uses · YouTube ↗
      Adds Peak's marine collagen to his routine for a powerful longevity ritual, supporting skin elasticity, hydration, hair, nails, and whole body vitality.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 14 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
    • 9 Sep 2026 · Vitamin C · uses · YouTube ↗
      Used intravenous vitamin C cocktails to help him detoxify and recover from chronic fatigue.
    • 19 Aug 2026 · uses · YouTube ↗
      Adds Peak's Carrera Marine Collagen to their morning ritual for a powerful longevity ritual, supporting skin elasticity, hydration, hair, nails, and whole body vitality.
    • 17 Aug 2026 · neutral · YouTube ↗
      States that collagen powder may modestly improve elasticity and hydration of the skin.
    • 17 Aug 2026 · neutral · Podcast ↗
      Notes that most people focus on collagen powders for skin aging, but healthy skin is built inside the body.
  • Andrew Huberman · Collagen · uses
    • 7 Aug 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 20 Jul 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 13 Jul 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 6 Jul 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for skin health.
    • 22 Jun 2026 · uses · X ↗
      Takes 10 grams of collagen in the morning for muscle.
    • 17 Jun 2026 · uses · X ↗
      Takes 10-20 grams of Collagen every day for muscle.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 6 Jun 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for muscle.
    • 22 May 2026 · uses · X ↗
      He takes 10 grams of Collagen in the morning for muscle.
    • 11 May 2026 · uses · X ↗
      Takes 10 grams of Collagen in the morning for skin health.
    • 4 May 2026 · uses · X ↗
      He takes 10 grams of Collagen in the morning for skin health.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
    • 16 Jun 2025 · Vitamin C · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
  • Dr. Rhonda Patrick · Collagen · stopped
    • 5 Aug 2025 · stopped · Podcast ↗
      Is no longer taking collagen.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 9 Jan 2026 · Vitamin C · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 29 Dec 2025 · Vitamin C · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 9 Sep 2025 · Vitamin C · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
    • 4 Sep 2025 · Vitamin C · neutral · Facebook ↗
      Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory.
    • 11 Aug 2025 · Vitamin C · uses · X ↗
      Currently takes the Pure Encapsulations O.N.E Multivitamin.
    • 3 Jul 2025 · uses · Facebook ↗
      Uses Hydrolyzed Collagen Peptides as a source of glycine and proline to support connective tissue and skin health.
    • 26 Jun 2025 · Vitamin C · uses · Facebook ↗
      Rhonda's current supplement routine includes Vitamin C.
    • 28 Apr 2025 · recommends · YouTube ↗
      Dr. Rhonda Patrick, who was previously unconvinced, now recommends hydrolyzed collagen powder prophylactically for connective tissue and ligaments, especially if someone has a soft tissue injury history, to be taken 30 to 60 minutes pre-exercise with 50 milligrams of vitamin C.
    • 22 Apr 2025 · neutral · Podcast ↗
      Discusses whether collagen can actually strengthen tendons.
  • Peter Attia · Collagen · neutral
    • 20 Jun 2024 · neutral · YouTube ↗
      Explains that collagen has a much lower quality amino acid composition than whey and tends to be rich in only a handful of amino acids like glycine and proline, making it less effective for muscle protein synthesis.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
    • 3 Jun 2024 · warns · YouTube ↗
      Advises that collagen protein is not a very complete protein and suggests supplementing it with something else if consumed, despite his wife's preference for it.
    • 28 Apr 2024 · warns · YouTube ↗
      Says that based on current data, there is no benefit in myofibrillar or muscle connective tissue protein synthesis using collagen versus whey or casein, especially in exercising individuals. He warns that using collagen as a sole supplemental protein source compromises myofibrillar muscle protein synthesis due to its poor amino acid balance.
    • 22 Apr 2024 · warns · YouTube ↗
      States that as a scientist, he hasn't seen evidence that collagen leads to greater connective tissue protein synthesis rates in muscle, but if he were recovering from a hip or knee injury, he would take a protein supplement with some collagen to ensure enough glycine and proline for ligaments, tendons, bone, and cartilage.
    • 7 Mar 2022 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C deficiency is associated with an elevated risk of cataract, supplementation to supranormal levels has been conclusively shown not to protect against cataract formation.
    • 24 Jan 2022 · Vitamin C · neutral · YouTube ↗
      Mentions that a survey of doctors showed they recommend Vitamin C for COVID-19, but notes there is no real evidence behind it.
    • 26 Oct 2020 · recommends · YouTube ↗
      Recommends collagen supplements, in either pill or powder form, for hair, skin, nails, bones, and for putting on and maintaining healthy muscle, as it's difficult to get enough from diet alone.
    • 19 Oct 2020 · Vitamin C · warns · YouTube ↗
      Expresses skepticism about 'panacea treatments' for cancer, specifically mentioning a 'twenty thousand dollars of vitamin C' treatment, implying it's an example of something he's 'squirrely' about due to cost and unproven claims.
    • 10 Aug 2020 · Vitamin C · recommends · YouTube ↗
      Asks if vitamin C matters for immune function, suggesting a need for a definitive study.
    • 12 Mar 2020 · Vitamin C · warns · YouTube ↗
      Warns against the "total nonsense" of taking excessive amounts of vitamin C, especially in specific forms like liposomal vitamin C, for immunity, stating that it is idiotic and potentially dangerous to think it will offer immunity.

RAL Summary

Members OnlyTier 2 for Younger-Looking Skin for Women

Collagen hydrolysate at a full 1000 milligram dose improved skin hydration, elasticity and wrinkles across several pooled reviews, the largest with 1721 people [1], and 88 percent of 721 reviews are positive.

Where the evidence disagrees: 2 of the 45 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Skin, Connective tissue

Combine with: Hydrolyzed collagen peptides paired with vitamin C is a well-founded skin-support combination, since vitamin C is an essential cofactor for collagen synthesis (prolyl and lysyl hydroxylase) and also acts as an antioxidant. To strengthen skin hydration and elasticity, consider stacking with hyaluronic acid (oral, 120-240 mg daily) for moisture retention, and ceramides or phytoceramides (30-350 mg) to support the skin barrier. Astaxanthin (4-12 mg) and other antioxidants such as vitamin E or polyphenols (grape seed extract, green tea) can help protect against UV and oxidative damage. Biotin, zinc and silica (or horsetail) support skin, hair and nails and connective tissue, while omega-3 fatty acids (EPA/DHA) help reduce inflammation and support skin lipids. For best results, take collagen consistently daily for 8-12 weeks, and pair it with daily broad-spectrum sunscreen and adequate protein intake.

Possible side effects: No major side effects reported; one collagen trial reported no side effects and vitamin C skin products had few side effects.

Supplement Facts

Vitamin C 50 mg · Collagen Hydrolysate 1000 mg
Supplement Facts
Serving Size 3 Capsule(s)
Servings Per Container 120
Amount Per Serving% Daily Value
Vitamin C50 mg
Collagen Hydrolysate1,000 mg†
† Daily Value not established.

Other ingredients: Dicalcium Phosphate, Gelatin, Magnesium Stearate.

Directions: Directions: Adults - Take three (3) capsules daily, as a dietary supplement, preferably on a empty stomach 30 minutes before meals.

Barcode (UPC) 676194176427 · Label source: NIH label database · Report a label change

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More younger-looking skin for women products

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Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.