Garden of Life Dr. Formulated Advanced Omega Citrus Flavor Review
Garden of Life Dr. Formulated Advanced Omega in Citrus Flavor is a fish oil supplement sold as softgels. The softgel shell is a non-GMO PlantGel. A serving is 2 softgels, and each container holds 180 servings. Per serving, the label lists 15 calories, 1.5 g of total fat and 1.45 g of PureSeaOmega3 MSC CoC-Grade Fish Oil. The other ingredients are PureSeaOmega3, the non-GMO PlantGel softgel, flavor and rosemary extract. The printed directions read: Suggested use: Adults take 2 softgels daily with food. Buyers most often say the citrus flavor keeps fishy burps and aftertaste away and that the softgels are small and easy to swallow. A few mention the price, and one found the citrus smell too strong over time.
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Study, Trial or Testing Result Summary
Members OnlyHuman studies
We were not given any study findings that test this product's fish oil, or any other ingredient in it, for blood pressure or heart health. Because of that, this summary cannot point to research showing whether it helps with blood pressure. The label we have is incomplete. It shows only a calorie line and lists no ingredient amounts, so we cannot check whether the fish oil is given at a dose that studies have used. The store listing describes the product as a citrus-flavored fish oil sold under the name PureSeaOmega3. Buyer reviews are strongly positive overall. Most of the praise is about the lack of fishy aftertaste and the small softgels, not about blood pressure. Only 2 of the 15 written reviews we read mention heart or blood pressure goals, and neither says it helped. Until human studies on this goal are added, treat any blood pressure benefit from this product as unproven. Animal and cell studies are never counted.
Review Totals and Summary
Members Only3,296 reviews · 92% positive
Buyers rate it well overall, with about 3296 ratings across the stores that sell it, and most of the comments are warm. The praise centers on the lack of fishy aftertaste and the small, easy softgels. A few buyers had problems with the citrus flavor or with how they felt after taking it. **What buyers say it did for them:** Several people report changes they noticed over weeks. One says "My eyes aren't as dry. My skin is behaving itself." Another took it for joint pain and saw "improvements in my mobility." A reviewer who tracks blood work says it works "as tested via my Omega Index blood test." Not everyone saw the same thing: one says there was no change in joints but feels "generally less inflamed lately." **What they complain about:** The negative reviews are few but pointed. One buyer reports "Causing chest pain and heart palpitations." Another says the citrus smell "becomes overwhelming after you have taken them for a while" and that the flavor gives them indigestion and flavored burps. That person likes the brand but will not buy again because there is no unflavored version. One reviewer also calls it expensive. **Taste, smell, pill size and form:** This is the biggest theme. Many say the citrus coating hides any fish taste: "no yucky burps after taking these." Another calls the flavor "pleasant, subtle lemon" with no aftertaste. On size, buyers call the softgels small and easy to swallow, though one notes "They aren't tiny though" and describes a football-like shape. Several mention the triglyceride form, and one likes that the label lists EPA and DHA amounts. **Value for money:** Opinions split a little. One buyer calls it "Expensive but better than most." Another finds the price "reasonable too for 3 months serving." **Who it seems to suit and who it did not:** It seems to suit people who dislike fishy burps, want a small softgel, and care about third-party testing, MSC grade or NSF certification, which several reviewers mention. It suited people who want a plain omega product with no added vitamins or fillers. It did not suit a buyer who is sensitive to citrus smell or flavor, and it did not work out for the reviewer who reported chest symptoms.
Biohacker Summary
Members Only7 of 10 recommend it
Omega-3 fatty acids are a smaller ingredient in this product, but all nine panelists who spoke about them said something, and most of the panel recommends or uses them. They take them for brain and mood, inflammation, heart health and triglycerides, skin, fertility and sperm health, muscle building, and slowing aging. Several prefer getting them from fatty fish such as salmon, sardines and mackerel, or from fish oil or cod liver oil, and one said fish sources may matter more than plant ones if seed oils are in the diet. Doses mentioned were 1 gram a day for aging, 1 to 3 grams for fertility, 2 to 4 grams for triglycerides, and 4 grams for muscle building, and one panelist warned that most people underdose because standard capsules hold little EPA and DHA. One advised taking them with a meal that contains fat for better absorption, and another said the research on hard heart disease outcomes is not very strong, though nobody reported stopping.
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Dr. Mark Hyman · Omega-3 Fatty Acids · neutral
- Explains why omega-3s are important for brain, mood, and healthy aging.
- Eats Zetopia's Atlantic salmon for Omega-3s and Vitamin D, especially in winter, noting that one serving provides as much EPA and DHA as two standard fish oil capsules.
- Mentions omega-3 fats as existing biomarkers that play a role in mental health, which Function Health includes in their measurements.
- Mentions that omega-3s are anti-inflammatory and helpful.
- Tries to supplement with omega-3s for psoriasis and considers them the one clearly clinically effective skin nutrient for skin, hair, and nails.
- Emphasizes the importance of focusing on omega-3s, noting that a national crisis of omega-3 deficiency exists and that low omega-3 levels are a significant problem, more so than omega-6s.
- Consumes omega-3 fats through salmon at dinner.
- Notes that omega-3s are important nutrients for brain performance and aging, and that many people have gaps in these nutrients.
- Recommends omega-3 fats from wild fish, seafood, and certain nuts and seeds to fight inflammation.
- Mentions omega-3 fats as something that might be helpful for gut repair.
Dr. Eric Berg · Omega-3 Fatty Acids · neutral
- Notes that one can of sardines contains 900 mg of omega-3s (EPA and DHA).
- Recommends Omega-3s from fish oil or cod liver oil to improve the omega-6 to omega-3 ratio, which should be around 2:1 or 1:1 but is often 10:1 or 20:1 for most people.
- Suggests that taking cod liver oil can help with flaky skin around the nose or forehead, which usually means too much omega-6 fat relative to omega-3 fat.
- Recommends fatty fish like salmon, sardines, and mackerel, which are high in omega-3 fatty acids (EPA and DHA) that reduce liver inflammation and prevent scarring.
- Recommends wild-caught salmon as a healthy food to eat every day, noting it contains about 2000 mg of omega-3s in just 3 ounces.
- Recommends wild salmon as it is rich in omega-3 fatty acids, which help reduce inflammation and support brain health and cognitive function, especially important as one ages.
- Recommends DHA, an omega-3 fatty acid, as a natural remedy that, along with sweet wormwood, can trigger iron into an explosion to hit cancer.
- Dr. Eric Berg mentions that sardines are packed with omega-3 fatty acids, which support brain health and metabolism.
- Mentions that wild salmon, specifically half a fillet, has 970 mg of potassium, zero carbohydrates, a good amount of magnesium, and is loaded with omega-3 fatty acids.
- Discusses what would happen if one consumed omega-3 fatty acids every day for 30 days, highlighting their benefits for brain health, heart health, and various conditions like dry eyes, dermatitis, and high blood pressure, as well as supporting calcium absorption and promoting better sleep.
Thomas DeLauer · Omega-3 Fatty Acids · recommends
- Recommends eating more omega-3s to turn over cell membranes more quickly.
- Recommends fish oil supplements as an omega-3 source for gut health, as they help reduce inflammatory signaling while tissue repairs.
- Recommends high-dose omega-3s, specifically 2 to four grams of combined EPA and DHA daily, to lower hepatic fat output and improve chylomicron clearance, which helps with non-fasting triglycerides.
- Recommends omega-3s, specifically 4 grams a day, to boost the muscle building response by making muscle cell membranes work better for the mTor switch to fire, and specifically mentions Pury for their clean, third-party tested omega-3s.
- Recommends consuming more omega-3s to help balance the mitochondrial membrane, as it will absorb more omega-3s instead of omega-6s.
- Recommends consuming more omega-3s to drive down inflammation.
- Recommends omega-3s, stating that a meta-analysis found 1,000 mg significantly reduced liver fat by shutting down inflammatory signals that promote fat storage, and advises looking for a triglycerol form for better absorption and to avoid oxidation.
- Recommends fatty fish like salmon and sardines, aiming for two to three servings per week, especially around a workout, because their omega-3s, particularly DHA, increase BDNF expression.
- Considers omega-3s a fundamental for brain protection, recommending both dietary sources and supplementation for EPA and DHA, as they produce pro-resolving mediators to limit inflammation.
- Recommends timing omega-3 intake around workouts because they directly help build and keep muscle by making muscle more responsive to growth signals and fighting anabolic resistance as one ages.
Dr. Rhonda Patrick · Omega-3 Fatty Acids · neutral
- Notes that Omega-3s (EPA and DHA) are important for neuronal membranes, brain function, and resolving inflammation, and higher levels are associated with lower dementia risk.
- Highlights omega-3 fatty acids as important for cell membranes, neurons, supporting brain cells, the blood-brain barrier, and regulating inflammation, which can contribute to memory problems.
- Mentions that EPA is an omega-3 examined in mortality analysis and found primarily in seafood.
- States that Omega-3 fatty acids are very important for sperm health.
- Omega-3s may help slow biological aging, with added benefits when combined with vitamin D and strength training. In a 3-year randomized trial of healthy, mostly active older adults, omega-3 alone slowed several DNA-based aging clocks.
- Recommends regular intake of omega-3 rich seafood and supplementation with omega-3 fatty acids if it's appropriate for one's lifestyle, as they are beneficial for the heart by resolving inflammation and preserving membrane fluidity.
- Notes that a 100 mg per day increase in omega-3 fatty acids was associated with lowering the risk of Alzheimer's disease and cognitive decline by 10%, and that it takes about two grams a day to get to a high omega-3 index if one has a low index.
- Practical habits to help keep chronic inflammation in check include getting enough omega-3s.
- States that Omega-3s, specifically EPA and DHA, may be the most potent naturally occurring dietary compounds for reducing inflammation, and that about 2 g/day of combined EPA and DHA can raise a low omega-3 index.
- Recommends fatty fish as a source of healthy fats for muscle gain.
Andrew Huberman · Omega-3 Fatty Acids · recommends
- Mentions that AG1 is giving away a free bottle of omega-3 co-enzyme Q10 with the first subscription to AG1 Pro.
- AG1 is giving away a free bottle of omega-3 coenzyme Q10 with your first subscription.
- Mentions that AG1 is giving away a free bottle of Omega-3 co-enzyme Q10 with the first subscription to AG1 Pro.
- Discusses Omega-3 Fatty Acids and EPA.
- Mentions that AG1 is offering a free bottle of Omega-3 co-enzyme Q10 with a first subscription to AG1 Pro.
- Recommends a free bottle of Omega-3 co-enzyme Q10 with the first AG1 Pro subscription.
- Mentions Omega-3s in the context of the microbiome and processed foods.
- Recommends Omega-3 co-enzyme Q10, which is offered as a free bottle with the first AG1 Pro subscription.
- States that getting 1 to 3 grams of EPA essential fatty acid per day can improve mood and cognitive function, supporting focus and concentration.
- Discusses Omega-3 Fatty Acids.
Siim Land · Omega-3 Fatty Acids · recommends
- Recommends taking omega-3s, including EPA and DHA, with a fat-containing meal to increase absorption.
- Increased his omega-3 intake to achieve a higher omega-3 index, which is associated with greater insulin sensitivity and better metabolic health markers.
- Increased his omega-3 index to 9.5% and notes that omega-3s have strong evidence for reducing elevated triglycerides.
- Mentions that EPA and DHA Omega-3s support heart and brain function and can lower triglycerides, with a higher omega-3 index associated with lower heart disease, Alzheimer's and mortality risk.
- Recommends Omega-3s for triglycerides and cardiovascular health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
- Recommends choosing an omega-3 supplement from a brand that uses independent third-party testing and publishes a recent certificate of analysis, verifying EPA and DHA amounts, and testing for heavy metals, contaminants, and oxidation markers.
- Lists Omega-3s as one of 15 supplements backed by human studies.
- Explains that omega-3s can alter mitochondrial membranes and have broader cardiometabolic effects, making mitochondria more responsive to cellular signaling and oxidative stress from exercise, but they don't increase maximal mitochondrial respiration.
- Notes that 75% of people aren't meeting the daily recommendation for omega-3s and that Japanese people eat 2-3x more omega-3s per day than Americans or Europeans, which reflects in their higher omega-3 index.
- Thinks omega-3s have some of the strongest evidence and are worth considering.
Dave Asprey · Omega-3 Fatty Acids · recommends
- Suggests that omega-3s may help slow aging and support cellular repair.
- Recommends omega-3s, noting that 1 gram a day slowed epigenetic aging by up to 4 months in a randomized trial of people over 70.
- Dave Asprey recommends Omega-3, citing a randomized trial showing 1g a day slowed epigenetic aging in older adults, but warns that most people underdose due to low EPA and DHA content in standard capsules.
- A review of 41 human studies testing interventions against newer-generation epigenetic clocks found favorable changes for exercise, caloric restriction, omega-3s, plant-rich diets, multivitamins, a med, pitavastatin, and ketamine.
- Recommends getting nutrients like omega-3s from real food or Vision 101 for eyesight.
- Recommends adding omega-3 fats to improve how neurons absorb and use nutrients like vitamin C.
- States that Fatty15 supports cells better than omega-3s or fish oil, but he uses both.
- Notes that Inuit people consumed very high levels of omega-3s, specifically EPA and DHA, which contributed to their health on a whale blubber diet.
- Lists Omega-3s as a nutrient that forms the structure and different parts of the brain.
- Uses both C15 and omega-3s, noting that C15 supports cells better than omega-3s or fish oil with three times more benefits.
Ben Greenfield · Omega-3 Fatty Acids · neutral
- Notes that omega-3s have solid research behind them for fertility.
- Recommends omega-3 fatty acids, specifically EPA and DHA, at 1 to 3 grams per day for better sperm morphology and motility, noting that sperm membranes are rich in polyunsaturated fatty acids.
- Recommends getting Omega-3 from oily fish such as sardines, anchovies, mackerel, herring, and salmon with skin.
- Discusses why fatty fish or fish oil may matter more than plant-based omega-3s if seed oils are in one's diet.
- Says that omega-3 fatty acids are a great way to feed the system and help with stress.
- Recommends testing for and replenishing omega-3 fatty acids if levels are low, as they can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
- Recommends including EPA from fatty fish or fish oil in one's diet, especially if seed oils are present in the diet.
- Notes that B vitamins and Omega-3s work as a pair to support the brain, but not independently.
- Notes that the DO-Health study showed omega-3 had good effects, and it's a supplement people commonly take.
- Mentions that omega-3, vitamin D, and exercise all had good effects in the DO-Health study.
Peter Attia · Omega-3 Fatty Acids · neutral
- Peter and Michael explore the benefits of omega-3 fatty acids for cardiovascular trials and the challenge of delivering DHA to the brain.
- Mentions that some trials showing a benefit to PUFA were confounded by the inclusion of omega-3s, and argues that the literature on omega-3s is not super strong for decreasing hard cardiovascular disease endpoints.
- Took big doses of omega-3 postpartum to help maintain when she wasn't sitting down to eat full meals.
- Mentions consuming fatty fish, specifically sardines, as part of their diet, noting their high fat and protein content.
- Peter discusses how omega-3s from fish oil impact inflammation, heart health, and brain function, as well as the strengths and limitations of current research.
- Mentions the importance of DHA omega-3 fatty acids for neuronal membranes, which are concentrated in synapses and crucial for communication between neurons.
- Highlights the importance of DHA omega-3 fatty acids for neuronal membranes and communication between neurons, as they are concentrated in synapses.
- Discusses the mfsd2a transporter, which is specific to DHA in phospholipid form, and its role in blood-brain barrier integrity, noting that animal studies show disruption of this transporter causes significant breakdown of the blood-brain barrier and loss of omega-3 in the brain.
- States that there is a very strong clinical impression that high doses of omega-3s help with dry eye, primarily from an anti-inflammatory standpoint.
- Recommends omega-3 fatty acids, specifically DHA and EPA, for brain protection, especially for individuals with the APOE4 gene, stating that they require higher doses.
Bryan Johnson · Omega-3 Fatty Acids · uses
- Lists Omega-3 as a customer favorite.
- Recommends Omega 3 fatty acids as a supplement for skin health, noting they are in the Blueprint stack.
- During menopause, Bryan Johnson recommends ensuring adequate omega-3s for brain health.
RAL Summary
Members OnlyTier 4 for Blood Pressure
Tier 3 needs some study support, but no human studies on blood pressure were given for this fish oil, so the evidence is thin and supports only tier 4. So it is graded Tier 4, lower than the rules alone gave.
- Emerging: not enough evidence to rank higher yet.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system
Possible side effects: One buyer reported chest pain and heart palpitations. Another reported indigestion and citrus-flavored burps from the flavoring.
Supplement Facts
PureSeaOmega3 MSC CoC-Grade Fish Oil 1.45 g
| Calories | 15 | |
| Total Fat | 1.5 g | |
| PureSeaOmega3 MSC CoC-Grade Fish Oil | 1.45 g | † |
Other ingredients: PureSeaOmega3, non-GMO PlantGel softgel, Flavor, Rosemary extract.
Directions: Suggested use: Adults take 2 softgels daily with food.
Barcode (UPC) 658010124638 · Label source: NIH label database · Report a label change
Other sizes and barcodes: 60 Softgel(s), UPC 6 58010 12461 4 (on market)
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Graded November 11, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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