Kirkland Signature Fast Acting Lactase Review

Product Focus: Healthy AgingAlso covers:Digestion
Tier ⓘ
Tier 4 · Rank 15
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 15 within Tier 4 for Healthy Aging; 160 of 215 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
41 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
91% of 160
Biohacker Mentions
0 of 10

Study, Trial or Testing Result Summary

Members OnlyHuman studies

This product contains lactase, an enzyme that helps break down the milk sugar lactose. The label does not state how much lactase is in each serving, so the dose cannot be checked. For the goal of reversing aging or supporting cellular and DNA repair, we found no human studies of lactase at all. No study showed it improved aging markers, and none tested it and found no effect. There is simply no research linking this ingredient to this goal. The product has 160 counted reviews, and 91 percent of them are positive. However, no written reviews could be read, so we do not know what buyers were rating. They were most likely rating its use for milk digestion rather than any effect on aging. Our expert panel made no statements about this product. Members looking for help with aging or cell repair should know that nothing in the evidence we have supports this use. Its positive ratings do not show any benefit for this goal. Animal and cell studies are never counted.

Review Totals and Summary

Members Only160 reviews · 91% positive
160 reviews · Amazon 160
91% positive3% neutral6% negative

Extensive customer reviews and qualitative feedback are currently being aggregated for this product. Check back soon for a detailed sentiment analysis.

Biohacker Summary

Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it

Six of the ten panelists spoke about lactase, the main ingredient, and the group is mostly positive. Three of them recommend it, while the other three explain how it works without taking a side, saying it breaks down the milk sugar lactose so dairy causes less trouble. People take it because lacking the enzyme can lead to bloating, gas, pain and other dairy sensitivity symptoms. They advise taking it with a meal or just before eating milk or dairy, and one pointed to raw dairy, which still has the enzyme. No one gave a dose or a preferred form, and no one named anything to pair it with. One panelist said he usually prefers avoiding dairy over relying on enzymes, and another said needing it may call for a closer look at how the body handles milk.

See all 6 biohackers →Hide the biohackers
  • Dave Asprey · Lactase · recommends
    • 25 Dec 2025 · recommends · X ↗
      Recommends leaving Santa some enzyme support from MassZymes because 70% of adults lack the enzyme lactase to properly digest dairy.
    • 24 Dec 2025 · warns · TikTok ↗
      Warns that 70% of adults lack the enzyme lactase to properly digest dairy, leading to problems like bloating, breakouts, and autoimmune reactions.
    • 3 May 2025 · recommends · YouTube ↗
      Recommends taking lactase enzymes with dairy if one chooses to eat it, due to a high percentage of people lacking the enzyme to properly digest dairy.
    • 17 Dec 2019 · recommends · YouTube ↗
      Recommends taking lactase if one is sensitive to dairy, noting that the enzyme has been available for 40 years to solve lactose intolerance.
  • Ben Greenfield · Lactase · neutral
    • 20 Nov 2024 · neutral · TikTok ↗
      Discusses how the lactase enzyme might affect digestion.
    • 15 Nov 2024 · neutral · YouTube ↗
      Explains that lactase enzyme digests lactose sugars in dairy, making it less problematic for people sensitive to dairy.
    • 14 Sep 2019 · recommends · YouTube ↗
      Says that if someone doesn't have the gene to break down lactose, they can take lactase as a supplement to hack things.
    • 21 Jul 2018 · neutral · YouTube ↗
      Mentions lactase, which can be taken to digest lactose if one is lactose intolerant and consumes a lot of dairy.
    • Date not recorded · recommends · Website ↗
      Recommends taking a lactase enzyme before consuming milk or dairy products if one is lactose intolerant to aid digestion and prevent issues like leaky gut syndrome.
    • Date not recorded · recommends · Website ↗
      Ben states that taking a lactase enzyme can help break down lactose if one has lactose intolerance.
  • Dr. Eric Berg · Lactase · neutral
    • 29 Jun 2024 · neutral · YouTube ↗
      Explains that lactase is an enzyme that helps break down milk sugar (lactose) and is destroyed during pasteurization, but is present in raw dairy.
    • 17 Mar 2020 · neutral · YouTube ↗
      Explains that certain microbes in the small intestine can make lactase, an enzyme that helps break down milk sugar (lactose).
    • 11 Feb 2019 · neutral · Podcast ↗
      Dr. Berg explains that if someone is missing the enzyme lactase, milk sugar will be broken down by bacteria, leading to bloating and pain.
  • Peter Attia · Lactase · neutral
    • 31 Oct 2023 · neutral · YouTube ↗
      Explains that people take lactase milk because if they don't have the lactase enzyme, they can't break down lactose sugar in milk, leading to food sensitivity symptoms.
  • Dr. Mark Hyman · Lactase · recommends
    • 26 Mar 2022 · recommends · YouTube ↗
      Recommends taking a lactase enzyme replacement with a meal if you have lactose intolerance and want to consume dairy or accidentally ingest it.
    • 3 Jan 2022 · recommends · YouTube ↗
      Recommends taking a lactase enzyme replacement with a meal if one experiences bloating, distension, and gas from lactose intolerance and wishes to consume dairy.
    • 7 Nov 2021 · neutral · YouTube ↗
      Notes that lactase enzyme can help people break down dairy and tolerate it better, but typically recommends avoiding the food rather than relying on enzymes.
  • Thomas DeLauer · Lactase · neutral
    • 15 Jun 2018 · neutral · YouTube ↗
      Notes that people with lactose intolerance can usually take a lactase enzyme to help break down lactose, but this may warrant further investigation into the body's overall ability to break down milk.

RAL Summary

Members OnlyTier 4 for Healthy Aging

Tier 3 needs some study support, but no human studies of lactase for reversing aging or cellular and DNA repair were found, so the evidence is thin and supports tier 4. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.
  • No human studies on this goal for its ingredients.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Digestive system

Combine with: Combine with a healthy diet and lifestyle.

Possible side effects: No major side effects reported.

Supplement Facts

Lactase 0
Supplement Facts
Serving Size 1 Caplet(s)
Servings Per Container 180
Amount Per Serving% Daily Value
Sodium5 mg
Lactase0†
† Daily Value not established.

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Crospovidone, Magnesium Stearate, Silicon Dioxide, Colloidal.

Directions: How do you use this product? - Swallow one caplet with your first bite of dairy foods. - You may adjust the dose if necessary to two caplets with your first bite of dairy foods. - if you continue to eat dairy foods after 30-45 minutes, taking an additional caplet is recommended. How often can you use this product? - This product may be used every time you eat foods containing dairy. It can be used with every meal or snack, every day. Single serve pouches: One caplet per serving

Barcode (UPC) 096619561537 · Label source: NIH label database · Report a label change

Show entire label
The Kirkland Signature Fast Acting Lactase label, 180 Caplet(s)
Fast Acting Lactase, 180 Caplet(s)

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Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.