Microbe Formulas Inflamma Calm Review

Microbe Formulas Inflamma Calm is a plant-based dietary supplement. It comes as 120 capsules of 1,054 mg each. The retailer copy describes a combination of 11 plant-based "inflammation tamers" designed to help soothe chronic inflammation and return the body to an optimal state. Microbe Formulas is a US brand that sells detox-oriented "protocol" products. A 2023 Trustpilot review says the company has since rebranded as Cellcore. Inflamma Calm sits in the brand's foundational detox protocol as a support product for the body's anti-inflammatory pathways. **What it contains.** The listing names Pomegranate Extract as the first ingredient. The retailer pages I could read were cut off after that, so I can't confirm the other ten botanicals or their doses. Check the supplement-facts panel on the bottle or the official site before buying. **How it is meant to work.** 1. **Antioxidant and anti-inflammatory support.** The brand says the plant extracts can help nurture cells, support detoxification and support energy levels, while supporting the body's natural anti-inflammatory response. Polyphenol-rich botanicals like pomegranate are generally studied for neutralizing reactive oxygen species and modulating inflammatory signaling, such as NF-κB and COX-2 pathways. This is general plant pharmacology. The brand has not published product-specific clinical trials that I could find. 2. **Organ and mitochondrial support.** The Amazon listing says the extracts support liver, kidney and mitochondrial function. The aim is to help the body process and clear the byproducts that drive inflammatory load. 3. **BioActive Carbon delivery.** The brand's proprietary carbon is said to protect the ingredients and maximize their delivery and potency. The brand also says it directs each capsule's ingredients so they go where they're needed in the body. Independent evidence for this targeting claim is limited. **Dosing and use.** The brand recommends one capsule twice daily, or two capsules twice daily for people needing extra support. The brand describes the formula as gentle on sensitive systems, so users can raise the dose as needed. Pricing is typically around $39.95. **Caveats.** This is a dietary supplement. It is not intended to diagnose, treat or cure disease. Anyone who is pregnant, on meds or other medication, or managing a chronic condition should talk to a clinician first.

Product Focus: Joints and Mobility
Tier ⓘ
Tier 4 · Rank 1
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 1 within Tier 4 for Joints and Mobility; 47 of 70 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
43 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
95% of 293
Biohacker Mentions
0 of 10

Study, Trial or Testing Result Summary

Members OnlyHuman studies

No human studies on this goal were found for its ingredients. Animal and cell studies are never counted.

Review Totals and Summary

Members Only293 reviews · 95% positive
293 reviews · Google Shopping 293
95% positive0% neutral5% negative

I could not find a body of verified customer feedback specific to Inflamma Calm, so I can't give a reliable theme summary for the product itself. ReviewMeta's analysis shows "no reviews found" for the Inflamma Calm listing on Amazon. One price-tracking site lists only a single review. A Nigerian retailer page reports 26 reviews with a high approval percentage, but I could not read their text. Feedback on the Microbe Formulas brand shows a few themes, and they may not carry over to this product. - **Positive:** Supportive reviewers praise the brand's gentle, low-side-effect approach and its knowledgeable guidance on detox protocols. A blogger describes feeling a real change within about a week of starting the first-step supplements and fewer symptoms over a year. Joint pain, bloating, and brain fog were among her starting symptoms. - **Mixed results:** A commenter on a Formula 1 review said she and her husband were on the complete kit. He noticed no difference, and she was still battling Lyme disease. - **Product consistency:** One Amazon reviewer of a sister product complained that the label and listing did not match the bottle's ingredients. They said a reformulation added an ingredient they react badly to, though the company accepted a full refund. - **Customer service:** Trustpilot reviewers (four reviews, roughly 2.5 out of 5) report unanswered emails, delayed refunds, and wiped loyalty points after the Cellcore rebrand. One international buyer said an order to the UK never arrived. The sample is tiny. Overall, the brand draws praise for gentle, natural formulations, while the most critical comments focus on customer service, refunds and labeling accuracy. Treat Inflamma Calm results as unverified until more product-specific reviews are available.

Biohacker Summary

Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it

Our biohacker panel has not discussed this product’s ingredients yet.

RAL Summary

Members OnlyTier 4 for Joints and Mobility

So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.
  • No human studies on this goal for its ingredients.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Combine with: For joint comfort, pair it with glucosamine sulfate, chondroitin, and UC-II undenatured collagen for cartilage support, plus omega-3 fish oil (EPA/DHA) for complementary anti-inflammatory action. Add black pepper extract (piperine) or a phytosome form of curcumin if the turmeric is not already highly bioavailable, and consider MSM and vitamin D3 with K2 for connective tissue and bone support. If the user still wants healthy-aging support, add NMN or NR with TMG, resveratrol or pterostilbene, and PQQ or urolithin A, which target mitochondrial function, sirtuin activity, and cellular repair more directly. Check with a healthcare provider first, especially for anyone on meds, since turmeric, Boswellia, and omega-3s can affect bleeding risk.

Possible side effects: No major side effects reported.

Supplement Facts

Proprietary Blend 1054 mg
Supplement Facts
Serving Size 2 Capsule(s)
Servings Per Container 60
Amount Per Serving% Daily Value
Proprietary Blend1,054 mg†
† Daily Value not established.

Other ingredients: HPMC.

Directions: Directions: Take 2 capsules twice daily or as otherwise directed by a healthcare practitioner.

Barcode (UPC) 788000132586 · Label source: NIH label database · Report a label change

Show entire label

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Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.