MyVitalC Review

MyVitalC is a premium dietary supplement featuring ESS60, a meticulously processed and purified form of Carbon 60 (C60), also known as fullerene. This groundbreaking molecule, recognized with a Nobel Prize in Chemistry in 1996 for its discovery in 1985, consists of 60 carbon atoms arranged in a unique hollow spherical structure, often likened to a soccer ball. MyVitalC specifically utilizes ESS60, which stands for "Elemental Safe Spheres 60 atoms," distinguishing it from industrial-grade C60 and emphasizing its suitability for human and pet consumption through a specialized purification process. The ESS60 is typically dissolved in organic extra virgin olive oil, enhancing its bioavailability as it breaks down the crystalline powder into individual molecules for better absorption within the body. The primary mechanism of action for MyVitalC's ESS60 lies in its extraordinary antioxidant capabilities. Unlike conventional antioxidants that neutralize free radicals on a one-to-one basis and become inert, ESS60 possesses a unique cage-like structure that allows it to repeatedly absorb and neutralize multiple free radicals without depleting its structural integrity. This makes it an exceptionally potent "nano antioxidant," reportedly over 170 times more effective than Vitamin C. This potent free-radical scavenging property is crucial in combating oxidative stress, a major contributor to cellular damage, inflammation, aging, and various chronic diseases. At a cellular level, ESS60 is believed to interact with mitochondria, the powerhouses of cells, where it participates in ATP processes, the basis of cellular energy transfer. The "Buffering Oxidative Stress System" (BOSS) theory suggests that ESS60 can hold onto up to six negatively charged reactive oxygen species, preventing them from causing damage until the mitochondria can replenish their natural antioxidant defenses like glutathione and melatonin. This action helps to protect neural cells, improve energy production, and support overall cognitive function. Furthermore, ESS60's anti-inflammatory properties are thought to reduce inflammation by fighting off harmful substances that cause swelling and irritation, which can alleviate pain and stiffness associated with conditions like arthritis. It also supports gut health by neutralizing free radicals directly within the gastrointestinal lumen, protecting the intestinal mucosal barrier, and reducing inflammatory signaling pathways, thereby contributing to a balanced gut microbiome and potentially influencing the gut-brain axis. The brand also highlights its potential to enhance immune system function by increasing the production of white blood cells and cytokines, and even showing some probiotic properties.

Product Focus: Healthy AgingAlso covers:SkinMuscles and jointsBrain
Tier ⓘ
Tier 4 · Rank 29
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 29 within Tier 4 for Healthy Aging; 174 of 215 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
35 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
– no stars shown, 2 reviews
Biohacker Mentions
10 of 10
Cost per month
$55

Study, Trial or Testing Result Summary

Members Only81 human studies · 49 improved

7 of these 81 human studies gave the ingredient by drip, not by mouth.

81 human studies49 improved18 no effect56,358 people studied

None of the four studied ingredients in this product has a stated amount; each is hidden in a blend, so we cannot tell whether any reaches the dose used in studies. The main ingredient, fullerene, has never been tested in people for aging or cell repair. In animals, a modified form extended lifespan in mice lacking an antioxidant enzyme [1], a water-soluble form reduced brain damage after a stroke-like blockage in gerbils [2], and a water-soluble form partly protected rat kidneys [3]. Vitamin D has the strongest human evidence. Two thousand units daily for four years slowed shortening of the protective caps on chromosomes in older adults [4], and a small trial found it raised the enzyme that maintains those caps [5]. Vitamin C improved some skin and oxidative stress markers in trials, often alongside other ingredients [6][7], but one small trial in dialysis patients suggested harm. Vitamin E results are mixed. It lowered oxidative damage in an uncontrolled study [8], but it did not change DNA damage in older men [9] and increased oxidative damage in triathletes [10]. Animal and cell studies are never counted.

See all 81 studies →Hide the studies

Review Totals and Summary

Members Only2 reviews
2 reviews · Facebook 2

Customer feedback for MyVitalC consistently highlights several qualitative themes, painting a picture of a supplement that users perceive as having a broad range of positive impacts on their well-being. A frequently praised benefit is a significant improvement in sleep quality. Many customers report experiencing deeper, more restful sleep, leading to feelings of being refreshed upon waking and increased energy levels throughout the day. This enhanced sleep is often linked to a subsequent boost in daytime energy and vitality, with users noting they feel more energetic and can sustain activity for longer periods. Another prominent theme revolves around cognitive enhancement. Users frequently mention improved mental clarity, focus, and acuity, making it easier to concentrate on tasks and maintain productivity. Some individuals even describe feeling like they have regained the mental sharpness of their younger years. The anti-inflammatory properties of MyVitalC also receive considerable positive attention, with customers reporting noticeable relief from pain and stiffness, particularly those suffering from conditions like arthritis. One testimonial specifically details the return of usability to hands previously swollen with arthritis. Beyond these core benefits, customers often express a general sense of improved overall well-being and a feeling of "feeling better" after incorporating MyVitalC into their routine. Some users have observed positive changes in their physical appearance, such as improved skin quality and even the disappearance of gray hairs or enhanced hair growth. The product's perceived impact on longevity is also a strong motivator for many, with the 2012 rat study often cited as a reason for their belief in its long-term benefits. Furthermore, the product's use of organic extra virgin olive oil as a carrier is generally well-received, and the ease of consumption, often taken as small shots, is appreciated. While the price point is acknowledged as an investment, many customers deem it worthwhile due to the perceived benefits. There are also instances of users reporting positive effects on their pets, such as improved energy and health in older animals. Some customers specifically commend MyVitalC for being the original formulation from SES Research Inc., emphasizing their trust in the company's manufacturing background and the quality of their ESS60.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

The panel leans toward recommending or using vitamin D, with seven or eight of the ten speaking about it, and several also speak about vitamin C, so the product's two main ingredients get mixed but mostly positive reviews. For vitamin D, people take it for immune support, mood, brain health, bone health, muscle, and male fertility, and three of them say they take 5,000 IU of the D3 form each morning for general health or longevity. One panelist said most people are deficient and another said it only makes sense if you are deficient, one pairs it with K2 for calcium handling, and one warns against the synthetic ergocalciferol form. For vitamin C, two recommend it, one for detox and inflammation support and one to help the body reuse glutathione, while others point to its role in collagen and skin, and one says the best dose is unclear and very high doses might blunt some of the benefits of exercise. One panelist takes only vitamin C and vitamin D, and no one said they stopped taking either.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Vitamin D · neutral
    • 8 Nov 2026 · neutral · Facebook ↗
      Lists Vitamin D as an ingredient found in sardines.
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends Vitamin D3 because it's nearly impossible to get enough from food and most people don't get enough sun, advising to aim for blood levels of at least 50 to 80 ng/mL.
    • 7 Nov 2026 · neutral · Instagram ↗
      Dr. Berg states that when nutrients like vitamin D are too low, fatigue and weakness can follow.
    • 7 Nov 2026 · Vitamin E · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
    • 7 Nov 2026 · Vitamin C · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
    • 6 Nov 2026 · recommends · Podcast ↗
      Recommends focusing on vitamin D3 to support stronger bones if a neck hump is associated with osteoporosis.
    • 6 Nov 2026 · recommends · YouTube ↗
      Recommends a minimum of 10,000 IU of vitamin D per day to support natural killer cells.
    • 6 Nov 2026 · Vitamin C · neutral · Instagram ↗
      Mentions that bleeding or swollen gums point to vitamin C deficiency, and sugar competes with it directly, reducing absorption.
    • 5 Nov 2026 · recommends · Podcast ↗
      Suggests that increasing vitamin D3 may help address the underlying problem of bruxism.
    • 2 Nov 2026 · warns · Facebook ↗
      Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
    • 1 Nov 2026 · neutral · YouTube ↗
      States that magnesium is needed to absorb vitamin D.
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
    • 30 Oct 2026 · recommends · YouTube ↗
      Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
  • Dr. Rhonda Patrick · Vitamin D · neutral
    • 8 Nov 2026 · neutral · Instagram ↗
      Notes that vitamin D from sunlight, food, or supplements needs to undergo conversions in the liver and kidneys to become its active hormone form, calcitriol.
    • 4 Nov 2026 · neutral · Instagram ↗
      States that Vitamin D supplementation has been associated with a 40% lower dementia risk, and low levels are linked to a 50 to 80% higher risk.
    • 28 Oct 2026 · recommends · YouTube ↗
      Recommends getting adequate vitamin D, noting that people taking vitamin D supplements have a 40% lower risk of dementia, while those with lower vitamin D have a 50-80% higher risk.
    • 5 Oct 2026 · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 30 Sep 2026 · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 24 Sep 2026 · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
    • 25 Aug 2026 · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin E · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 28 Jul 2026 · recommends · Facebook ↗
      Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
    • 22 Jul 2026 · neutral · YouTube ↗
      Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
  • Thomas DeLauer · Vitamin C · recommends
    • 6 Nov 2026 · recommends · YouTube ↗
      Recommends whole food vitamin C, found in kiwi fruit, citrus, and bell peppers, to help clear uric acid by competing at kidney transporters, preventing reabsorption.
    • 5 Nov 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking Vitamin D3 in the morning, between 6:00 and 10:00 a.m., to align with the body's natural metabolic activation phase and sunlight-triggered vitamin D production.
    • 26 Oct 2026 · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 23 Oct 2026 · Vitamin D · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 20 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
    • 8 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
    • 6 Oct 2026 · Vitamin D · uses · YouTube ↗
      Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
    • 5 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
    • 4 Oct 2026 · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 29 Sep 2026 · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 29 Sep 2026 · Vitamin D · uses · YouTube ↗
      Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 11 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting vitamin D, suggesting it can be obtained while walking.
  • Dr. Mark Hyman · Vitamin D · uses
    • 4 Nov 2026 · uses · YouTube ↗
      Consumes Zetopia's Atlantic salmon to get Vitamin D, particularly in the winter months, as it is one of the few foods that provides both Omega-3s and Vitamin D.
    • 29 Oct 2026 · neutral · YouTube ↗
      Mentions that the body makes vitamin D from sunlight exposure, and a deficiency can hinder calcium absorption, which is crucial for strong bones.
    • 26 Oct 2026 · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 8 Oct 2026 · recommends · Instagram ↗
      Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
    • 7 Oct 2026 · neutral · Podcast ↗
      Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
    • 7 Oct 2026 · recommends · YouTube ↗
      States that vitamin D supplementation can help with oxidative stress.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · neutral · Podcast ↗
      Mentions vitamin D as a key nutrient for supporting immune function.
    • 5 Oct 2026 · recommends · YouTube ↗
      States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
  • Dave Asprey · Vitamin C · neutral
    • 3 Nov 2026 · neutral · YouTube ↗
      Recounts a doctor telling him in his 20s that vitamin C would kill him.
    • 1 Nov 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 25 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 24 Oct 2026 · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 9 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin D · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin E · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
    • 5 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
    • 3 Sep 2026 · Vitamin D · recommends · YouTube ↗
      States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
    • 29 Aug 2026 · Vitamin D · recommends · YouTube ↗
      Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
    • 24 Aug 2026 · ESS60 · recommends · Facebook ↗
      Recommends ESS60, a purified form of C60 suspended in olive oil, as an antioxidant that continuously neutralizes free radicals.
    • 18 Aug 2026 · Vitamin D · recommends · YouTube ↗
      Recommends Vitamin D as one of the most important supplements for overall health.
    • 18 Aug 2026 · Vitamin E · recommends · YouTube ↗
      Recommends Vitamin E as one of the most important supplements for overall health.
  • Siim Land · Vitamin D · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 24 Oct 2026 · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks vitamin D has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · neutral · X ↗
      Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 26 Aug 2026 · recommends · Instagram ↗
      Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
    • 23 Aug 2026 · neutral · X ↗
      Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
    • 17 Aug 2026 · recommends · X ↗
      Recommends taking Vitamin D in the morning or at lunch with fat.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron improves vitamin D.
    • 5 Aug 2026 · recommends · YouTube ↗
      Recommends Vitamin D because microglia contain Vitamin D receptors, and Vitamin D helps keep the immune system properly regulated, with low levels associated with greater neuroinflammation and a higher risk of autoimmune conditions.
  • Ben Greenfield · Vitamin E · neutral
    • 29 Oct 2026 · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 29 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 20 Aug 2026 · Vitamin D · uses · YouTube ↗
      Has been taking Vitamin D3 K2 for over a decade.
    • 8 Aug 2026 · Vitamin D · neutral · Instagram ↗
      Notes that sunlight influences more than just vitamin D production.
    • 8 Aug 2026 · Vitamin D · recommends · YouTube ↗
      Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
    • 18 Jul 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting enough vitamin D for blood pressure management.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
    • 9 Jul 2026 · Vitamin D · recommends · YouTube ↗
      Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
  • Bryan Johnson · Vitamin D · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 3 Jul 2026 · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 2 May 2026 · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 21 Apr 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 14 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 8 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 7 Apr 2026 · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
  • Andrew Huberman · Vitamin D · neutral
    • 21 Sep 2026 · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 7 Aug 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 20 Jul 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 20 Jul 2026 · recommends · YouTube ↗
      States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 13 Jul 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning.
    • 12 Jul 2026 · uses · X ↗
      He takes 5,000 IU of Vitamin D3 in the morning for overall health.
    • 6 Jul 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning.
    • 22 Jun 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for general health.
    • 17 Jun 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 every day for longevity.
    • 17 Jun 2026 · Vitamin E · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 6 Jun 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
  • Peter Attia · Vitamin D · uses
    • 4 Jan 2026 · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 16 Nov 2025 · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 6 Aug 2025 · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 3 Aug 2025 · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 10 Jul 2025 · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
    • 6 Jul 2025 · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 8 Jun 2025 · recommends · YouTube ↗
      Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
    • 17 Mar 2025 · neutral · Instagram ↗
      Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.

RAL Summary

Members OnlyTier 4 for Healthy Aging

Emerging tier because every studied ingredient is hidden in a blend with no stated amount, and the main ingredient, fullerene, has only animal and laboratory evidence [1]. Vitamin D has good human trials for aging markers, but at doses that cannot be confirmed here [4].

  • Emerging: not enough evidence to rank higher yet.
  • C60 (fullerene): amount hidden in a blend
  • Vitamin D: amount hidden in a blend
  • Vitamin C: amount hidden in a blend
  • Vitamin E: amount hidden in a blend

Where the evidence disagrees: 18 of the 81 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Cellular and DNA health, Skin, Musculoskeletal system, Nervous system

Combine with: To enhance the anti-aging and cellular repair benefits of C60, consider combining it with other potent antioxidants and compounds that support cellular health and longevity pathways. Alpha-lipoic acid and CoQ10 can further bolster mitochondrial function and antioxidant defenses. NAD+ precursors like NMN or NR are excellent for supporting cellular energy and DNA repair mechanisms. Resveratrol or Fisetin can activate sirtuins, which are crucial for cellular longevity. Additionally, Omega-3 fatty acids can support overall cellular membrane integrity and reduce inflammation, complementing C60's protective effects.

Possible side effects: High-dose vitamin E increased oxidative damage and inflammation during exercise in athletes, and vitamin E with vitamin C blocked insulin sensitivity gains from exercise. One small trial suggested vitamin C may cause harm in dialysis patients.

Supplement Facts

Sugar 0 g · ESS60 ~ 80mg/100ml 0 · Vitamin D 0
Supplement Facts
Serving Size 1 tsp (5ml)
Servings Per Container 24
Amount Per Serving% Daily Value
Calories40
Calories from Fat40
Total Fat4.6 g7.3%
Saturated Fat890 mg4%
Trans Fat0 g
Cholesterol0 mg
Sodium0 mg
Total Carbohydrate0 g
Dietary Fiber0 g
Sugar0 g†
Protein0 g
ESS60 (C60) ~ 80mg/100ml†
Vitamin D0
Vitamin C0
Vitamin E0
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.

Other ingredients: Extra Virgin Olive Oil, ESS60™.

Label source: Amazon · Report a label change

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Graded October 24, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.