Nature Made Potassium Gluconate Review

Product Focus: Blood PressureAlso covers:Heart
Tier ⓘ
Tier 4 · Rank 22
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 22 within Tier 4 for Blood Pressure; 44 of 49 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
15 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Biohacker Mentions
0 of 10

Study, Trial or Testing Result Summary

Members Only43 human studies · 17 improved
43 human studies17 improved18 no effect80,871 people studied

Potassium has fairly strong human support for lowering blood pressure, but this product gives only 90 milligrams a day, far below the 30 millimoles a day that worked in trials, so these results may not apply at this dose. Most of the evidence also comes from potassium-enriched salt substitutes rather than potassium gluconate pills. In 26 trials with about 35,000 adults, swapping regular salt for low-sodium, potassium-enriched salt lowered the top blood pressure number by about 4.8 points and the bottom number by about 2.4 points [1]. In 22 trials with 1,606 adults, eating more potassium lowered the top number by about 3.5 points, mainly in people who already had high blood pressure [2]. A review of 32 trials found the benefit was largest in people with high blood pressure and high salt intake, but weakened at higher doses [3]. A pooled analysis of 120 trials found potassium-enriched salt beat usual care, though a healthy eating plan worked best [4]. In 2,376 villagers in Peru, a potassium salt substitute cut the risk of new high blood pressure by 51% [5]. In 608 people, potassium-enriched salt lowered the top number by 2.2 to 7.2 points over a year [6]. Many smaller studies found no effect. Animal and cell studies are never counted.

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Review Totals and Summary

Members OnlyWhat buyers say

No written reviews read yet.

Biohacker Summary

Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it

Potassium is the main ingredient here, and most of the panel recommends or uses it, with four of the ten recommending it outright and three more using it through electrolyte drinks or mineral blends. Their reasons include healthy blood pressure, muscle and heart function, hydration, fewer cramps, recovery, and less water retention. One panelist gives a daily need of 4,700 mg, and another says a smoothie of avocado and banana reaches about 5,800 mg. Several prefer getting potassium from foods like bananas and potatoes, while others take it in electrolyte drinks, potassium citrate, or in combination with sodium and magnesium, often first thing in the morning, during exercise, or during a fast. For caution, one panelist says potassium can be risky for people with kidney disease or other conditions that raise potassium levels and advises seeing a physician, and another notes that meds can flush potassium out; none of the panel reported stopping it.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Potassium · recommends
    • 29 Oct 2026 · recommends · Podcast ↗
      States that people need more potassium than any other mineral, yet most people aren’t getting enough.
    • 28 Oct 2026 · recommends · YouTube ↗
      Explains that potassium is essential for peristalsis, the pumping action through the colon, and without it, things can sit there, leading to constipation.
    • 25 Oct 2026 · neutral · YouTube ↗
      Explains that the normal requirements for potassium are 4,700 mg every single day, and that very few people get half of that amount. They describe potassium's role in the sodium potassium pump, which is essential for cellular electricity, muscle contraction, and heart function. Deficiency can lead to tiredness, muscle cramps, heart palpitations, or rising blood pressure.
    • 25 Oct 2026 · recommends · X ↗
      Recommends increasing potassium to restore balance and support healthy blood pressure.
    • 23 Oct 2026 · recommends · YouTube ↗
      States that potassium is the most important electrolyte and that most people are not getting enough of it, needing around 4,700 mg daily, or even more, to avoid issues like fatigue, muscle cramps, heart palpitations, high blood pressure, and fluid retention.
    • 23 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that potassium is essential for health, supporting healthy muscles, nerves, and heart function, but warns that getting too much, especially from supplements, can be dangerous.
    • 23 Oct 2026 · recommends · Instagram ↗
      Dr. Eric Berg states that most people are getting nowhere near enough potassium to balance the amount of sodium they’re already eating, implying a recommendation for increased potassium intake.
    • 20 Oct 2026 · neutral · YouTube ↗
      Explains that potassium relaxes blood vessels, keeps elasticity in arteries, lowers adrenaline, supports the sympathetic nervous system, protects the endothelial layer of arteries, increases nitric oxide, and keeps insulin receptors sensitive.
    • 19 Oct 2026 · uses · YouTube ↗
      Was very successful in practice using potassium for hypertension, noting that bodies need 4700 mg of potassium every single day.
    • 19 Oct 2026 · neutral · YouTube ↗
      States that low potassium can lead to constipation because potassium controls the smooth muscles of the body, affecting the contraction and relaxation of muscles in the colon.
  • Thomas DeLauer · Potassium · uses
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 100 milligram potassium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 100 mg potassium cans first thing in the morning to prime his day and help with workout performance.
    • 29 Aug 2026 · recommends · YouTube ↗
      Recommends Element's ready-to-drink sparkling electrolyte drinks as a low or zero-calorie soda replacement that provides 1,000 milligrams of sodium, 200 milligrams of potassium, and 60 milligrams of magnesium.
    • 29 Aug 2026 · uses · YouTube ↗
      Uses Element Electrolytes for about eight years, noting they contain 1000 mg sodium, 200 mg potassium, and 60 mg magnesium, and help curb appetite without adding many calories.
    • 8 Aug 2026 · uses · YouTube ↗
      Personally drinks Element's pink lemonade or sparkling drinks, which contain 1,000 mg sodium, 200 potassium, and 60 magnesium, to hydrate and feel satiated, curbing hunger without stopping the ghrelin response.
    • 30 Jul 2026 · uses · Instagram ↗
      Sometimes pivots to straight potassium supplementation when generally depleted.
    • 30 Jul 2026 · uses · YouTube ↗
      Uses Element ready-to-drinks as a perfect electrolyte blend to start his day, noting that they contain 500 mg of sodium, 100 mg of potassium, and 30 mg of magnesium, and are slightly carbonated.
    • 18 Jul 2026 · neutral · YouTube ↗
      Mentions potassium as an important electrolyte but suggests there's another layer to performance beyond just focusing on it.
    • 26 Jun 2026 · recommends · YouTube ↗
      States that potassium is important for hydration, skin repair, and fluid balance in the skin, and recommends countering sodium intake with potassium.
    • 25 Jun 2026 · uses · YouTube ↗
      Sips on LMNT Recharge cans throughout the day, especially when fasting, noting they are a new smaller can with 500 mg sodium, 100 mg potassium, and 30 mg magnesium.
  • Ben Greenfield · Potassium · uses
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 17 Aug 2026 · recommends · Instagram ↗
      Recommends Celtic Sea Salt's new electrolyte drink 'Hydrate' for replenishing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, magnesium, taurine, and potassium, with no added sugar, artificial colors, or synthetic ingredients.
    • 10 Jul 2025 · recommends · YouTube ↗
      Recommends adding potassium sulfate to a Morasco cold plunge.
    • 10 Apr 2025 · neutral · YouTube ↗
      Mentions that potassium can be helpful for blood pressure but also risky for people with kidney disease or other conditions prone to elevated potassium levels, advising consultation with a physician.
    • 11 Apr 2024 · warns · YouTube ↗
      Warns of potassium deficiency on a carnivore diet if a lot of octopus and salmon are not consumed.
    • 2 Nov 2023 · recommends · YouTube ↗
      Highlights the importance of potassium for numerous body benefits, noting that Vascanox is a good source of potassium nitrite.
    • 12 Oct 2023 · uses · YouTube ↗
      Anthony plans to do half sodium citrate and half potassium citrate to get the citrate for pH balancing and add more potassium.
    • 27 Feb 2020 · recommends · YouTube ↗
      Recommends ensuring sufficient potassium intake, along with calcium and magnesium, to balance the acid load from protein on a carnivore diet and normalize urinary pH.
    • 21 Mar 2019 · neutral · YouTube ↗
      Mentions Kali Phos (potassium phosphate) as another example of a tissue salt.
    • 27 Dec 2018 · recommends · Podcast ↗
      Suggests using potassium as a supplement for fasted workouts.
  • Dr. Mark Hyman · Potassium · warns
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that potassium bromate, a dough conditioner banned in the EU, UK, and Canada, is still allowed in U.S. bread.
    • 20 Aug 2026 · neutral · YouTube ↗
      States that potassium plays a critical role in nerve signaling and muscle contraction, especially in the heart, and low levels can lead to dangerous irregular heart rhythms.
    • 28 Jul 2026 · neutral · Facebook ↗
      Notes that meds flush out potassium.
    • 17 Jun 2026 · recommends · TikTok ↗
      States that with potassium, water can fully cross the cell membrane and get inside where it's needed for intracellular hydration.
    • 18 May 2026 · recommends · YouTube ↗
      Recommends using targeted electrolyte support, advising to look for products with meaningful amounts of sodium, potassium, and magnesium, low sugar content, and avoidance of artificial colors, flavors, and sweeteners.
    • 12 May 2026 · warns · Facebook ↗
      Warns that potassium bromate, a chemical dough conditioner, has been linked to cancer, oxidative stress, DNA damage, and reproductive harm in animal studies.
    • 26 Jan 2026 · warns · Facebook ↗
      Warns that electrolyte drinks, while marketed for hydration, are loaded with high-glycemic sugars, synthetic potassium salts, and artificial dyes that can trigger insulin resistance, blood sugar crashes, and inflammation.
    • 22 Oct 2025 · recommends · YouTube ↗
      Recommends promoting potassium enriched low sodium salts as a great life hack, stating that changing the brand of salt used at home can reduce the risk of heart attack, stroke, or early death.
    • 18 Jun 2025 · warns · YouTube ↗
      Warns that if potassium is trailing high, it's not necessarily about needing a banana, but rather a systematic marker indicating acute or chronic fatigue, overtraining, or sympathetic overdrive.
    • 2 Apr 2025 · recommends · YouTube ↗
      Notes that 96% of the US population does not meet the adequate intake for potassium, and that the ideal ratio of potassium to sodium should be 10 to 1, but it's currently the other way around. They explain that potassium plays an important role in regulating blood pressure.
  • Siim Land · Potassium · neutral
    • 30 Sep 2026 · neutral · X ↗
      Lists potatoes and fruit as sources of Potassium.
    • 31 Jul 2026 · neutral · X ↗
      Notes that bananas have potassium but there are at least 8 other foods with more potassium than bananas.
    • 31 Jul 2026 · neutral · X ↗
      States that potassium is the most abundant intracellular cation that helps to maintain intracellular fluid volume and that without it, one greatly increases the risk of hypertension, cardiovascular disease, diabetes, and stroke.
    • 29 Aug 2025 · neutral · YouTube ↗
      States that potassium lowers blood pressure.
    • 28 Mar 2025 · uses · YouTube ↗
      Travels with Upgraded Formulas' potassium, manganese, boron, and zinc, considering them fundamental minerals he is usually deficient in.
    • 5 Aug 2024 · warns · YouTube ↗
      Notes that potassium bromate is banned in the EU due to being a possible carcinogen, while it is allowed in the US as a whitening and raising agent in bread products.
    • 6 Mar 2024 · uses · YouTube ↗
      Found that adding 198 MGS of potassium to his diet within 24 hours stopped his frequent urination, which had been occurring 30 to 50 times a day.
    • 28 Sep 2022 · recommends · YouTube ↗
      Recommends potassium for muscle cramps, noting that a Carnivore diet may lack it, and suggests adding fruit or mineral waters.
    • 2 Sep 2022 · neutral · YouTube ↗
      Mentions potassium as an electrolyte needed to help with insulin sensitivity, alongside magnesium and sodium.
    • 17 Jan 2022 · neutral · YouTube ↗
      Notes Bryan Johnson uses New Salt, a low sodium, high potassium salt, but questions its necessity given Johnson's diet and low blood pressure, suggesting it may not have longevity effects unless one has actual high blood pressure.
  • Peter Attia · Potassium · recommends
    • 6 Sep 2026 · recommends · YouTube ↗
      States there is some evidence that increasing dietary potassium through potassium-rich foods like bananas and potatoes, rather than supplements, can lower blood pressure.
    • 26 Oct 2020 · recommends · YouTube ↗
      Notes that evolutionary ancestors consumed much more potassium than modern humans and suggests adding it back to the diet, ideally through whole foods.
    • 31 Dec 2019 · uses · YouTube ↗
      Mentions taking magnesium and potassium in addition to salt for minerals and electrolytes.
  • Andrew Huberman · Potassium · uses
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 18 May 2026 · uses · YouTube ↗
      Uses Element, which contains potassium in the correct ratios, to ensure proper hydration and electrolyte intake for brain and body function.
    • 26 Mar 2026 · neutral · Podcast ↗
      Mentions potassium as an electrolyte.
    • 12 Jan 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, drinking it first thing in the morning and during physical exercise.
    • 22 Dec 2025 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure he is hydrated and has sufficient electrolytes. He drinks it first thing in the morning and during physical exercise, especially on hot days.
    • 10 Nov 2025 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium but no sugar, to ensure adequate hydration and electrolytes, especially when waking up and during exercise.
    • 27 Oct 2025 · uses · YouTube ↗
      Uses LMNT, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes for brain and body function, especially when starting his day fast or during physical exercise.
    • 25 Aug 2025 · uses · YouTube ↗
      Uses Element, which contains potassium, for proper hydration and electrolyte balance.
    • 9 Jun 2025 · uses · YouTube ↗
      Ensures adequate intake of sodium, magnesium, and potassium, which are vital electrolytes for the functioning of all body cells, especially neurons, by drinking Element.
    • 26 May 2025 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium, to ensure adequate hydration and electrolytes for optimal brain and body function, especially when waking up and during physical exercise.
  • Dr. Rhonda Patrick · Potassium · recommends
    • 23 Jun 2026 · recommends · Facebook ↗
      Recommends getting enough potassium, noting that most people get too much sodium and not enough potassium.
    • 29 May 2024 · recommends · YouTube ↗
      States that maintaining a high potassium intake is important for hypertension.
    • 11 Feb 2015 · recommends · YouTube ↗
      Recommends getting enough potassium from veggies, bananas, and fruit because the body cares about the sodium-potassium ratio.
    • 6 Jan 2015 · uses · YouTube ↗
      Dr. Patrick states that her smoothie, containing avocado and banana, has around 5,800 milligrams of potassium, which meets the adequate intake requirement for maintaining normal blood pressure and decreasing the risk of kidney stones.
    • Date not recorded · neutral · Website ↗
      Dr. Rhonda Patrick states that eating more potassium, not less sodium, is the key to healthy blood pressure.
  • Dave Asprey · Potassium · recommends
    • 7 Feb 2026 · recommends · YouTube ↗
      Recommends having more potassium during a fast to increase mineral intake.
    • 6 Jan 2026 · recommends · YouTube ↗
      States that people who are salt-sensitive hypertensives usually need more potassium.
    • 1 Jan 2026 · neutral · Podcast ↗
      Explains why electrolytes, especially sodium, potassium, and magnesium, are foundational for recovery.
    • 1 Jan 2026 · recommends · YouTube ↗
      States that potassium is a really important electrolyte for everyone, but the demand is significantly higher for people with nervous system, immune system, and endocrine system dysregulation.
    • 30 Dec 2025 · recommends · YouTube ↗
      Recommends using potassium citrate, if tolerated, to raise urinary citrate and block crystal formation.
    • 4 Dec 2025 · neutral · YouTube ↗
      Notes that the potassium in the Vineia blood flow hydration product is from coconut water.
    • 26 Aug 2025 · neutral · YouTube ↗
      Mentions that atrial fibrillation has to do with mineral status, including potassium.
    • 7 Aug 2025 · uses · YouTube ↗
      Takes a lot of potassium.
    • 5 Aug 2025 · recommends · YouTube ↗
      Recommends lots of potassium citrate to help remove oxalates from the body.
    • 26 Jun 2025 · uses · YouTube ↗
      Dave Asprey, who is salt-sensitive, balances out sodium intake with potassium, taking potassium citrate capsules from Designs for Health and carrying them all the time.
  • Bryan Johnson · Potassium · recommends
    • Date not recorded · recommends · Website ↗
      Recommends potassium during the luteal phase to help reduce water retention and bloating.

RAL Summary

Members OnlyTier 4 for Blood Pressure

Potassium lowers blood pressure in several large reviews of trials, mostly through salt substitutes at much higher amounts than this 90 milligram product, and with no reviews counted the evidence for this product stays emerging.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 18 of the 43 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Cardiovascular system

Possible side effects: No major side effects reported; salt substitute trials found little change in high blood potassium.

Supplement Facts

Potassium 90 mg
Supplement Facts
Serving Size 1 Tablet(s)
Servings Per Container 100
Amount Per Serving% Daily Value
Potassium90 mg

Other ingredients: Cellulose Gel, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Silicon Dioxide.

Directions: Suggested use: Adults, take 1 tablet daily with water and a meal.

Barcode (UPC) 031604013585 · Label source: NIH label database · Report a label change

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Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.