Nature's Bounty Calcium With D3 Peach, Banana & Cherry Review
Nature's Bounty Calcium With D3 in Peach, Banana and Cherry flavors is a chewable gummy supplement. One serving is 3 gummies, and each container holds 30 servings. Per serving, the label prints these amounts: Calories 30, Total Carbohydrates 8 g, Vitamin D 600 IU, Calcium 600 mg, Phosphorus 290 mg, and Sodium 15 mg. The other ingredients listed are sugar, glucose syrup, pectin, citric acid, natural colors, and natural flavors. The directions printed on the label read: for adults, take three gummies daily, preferably with meals. Because the serving is three gummies and a container holds 30 servings, the daily directions on the label call for three gummies each day from one container. The gummies are made with pectin and flavored with natural flavors, and the label lists sugar and glucose syrup as the first two other ingredients. Check the label on the package in your hand for the full panel and any other printed information. As for what buyers say, the one review available describes the gummies as too thick and stuck together, so texture is the only point of feedback on record.
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Study, Trial or Testing Result Summary
Members Only57 human studies · 22 improved
1 of these 57 human studies gave the ingredient by drip, not by mouth.
Vitamin D is the main studied ingredient here, and two servings a day give a full dose. In people with type 2 diabetes, two large pooled analyses found that vitamin D modestly lowered fasting blood sugar, the long-term blood sugar marker and insulin resistance, most in people low in vitamin D [1][2]. In adults with prediabetes, vitamin D cut the risk of developing diabetes by 15% over about 3 years [3]. In pregnant women it lowered the risk of pregnancy diabetes by about 36% [4]. Not all results agree: a large trial of older adults taking 2000 units daily for about 5 years found no significant drop in diabetes risk [5], and another pooled analysis in prediabetes found no change in fasting blood sugar, though the glucose tolerance test improved [6]. Calcium is at a full dose, but most of its support comes from trials pairing it with vitamin D, such as lower fasting insulin and insulin resistance in 307 men [7] and lower fasting blood sugar in pregnant women [8][9], so its own share is unclear. Phosphorus has only two studies in a diabetes emergency, and neither showed a benefit for blood sugar [10][11]. Animal and cell studies are never counted.
See all 57 studies →Hide the studies
- Across 53 trials of 9,443 pregnant women, vitamin D supplements lowered the risk of gestational diabetes by about 36% and improved blood sugar, blood fat, inflammation and oxidative stress markers.Dietary supplementation for gestational diabetes prevention and management: a meta-analysis of randomized controlled tri…
- In 46 trials of 4,313 people with type 2 diabetes, vitamin D lowered HbA1c by 0.20 points, fasting glucose by 5 mg/dl and insulin resistance, most in people who were deficient and with high doses over a short time.What is the impact of vitamin D supplementation on glycemic control in people with type-2 diabetes: a systematic review …
- In 39 trials of 2,982 people with type 2 diabetes, vitamin D lowered fasting glucose, HbA1c by 0.30 points, insulin resistance and fasting insulin, especially with short-term high doses in deficient or overweight people.Efficacy of vitamin D supplementation on glycaemic control in type 2 diabetes: An updated systematic review and meta-ana…
- In 15 trials of 2,833 pregnant women, two trials of 219 women found no clear difference in gestational diabetes risk between vitamin D and placebo or no treatment, though the evidence was very low quality.Vitamin D supplementation for women during pregnancy.
- In 8 trials with 1,580 people with prediabetes, vitamin D did not change HbA1c, fasting glucose or insulin resistance versus placebo but improved the 2-hour glucose tolerance test result.Association between vitamin D and prediabetes: A PRISMA-compliant meta-analysis.
- Across five trials of 306 pregnant women with gestational diabetes, vitamin D plus calcium lowered fasting blood sugar, insulin and LDL cholesterol, but did not change total cholesterol or triglycerides.Influence of vitamin D-calcium on metabolic profile for gestational diabetes: a meta-analysis of randomized controlled t…
- A pooled analysis of Iranian studies found vitamin D improved fasting glucose, HbA1c and insulin resistance in people with type 2 diabetes, while gestational diabetes showed gains only in insulin resistance.The effects of vitamin D supplementation on indices of glycemic control in Iranian diabetics: A systematic review and me…
- In 27 trials in pregnant women, vitamin D above 2000 IU a day lowered the risk of gestational diabetes by 30%, but did not change preterm birth or birth weight, and lower doses were enough to reduce preeclampsia.Vitamin D supplementation higher than 2000 IU/day compared to lower dose on maternal-fetal outcome: Systematic review an…
- In three placebo-controlled trials of adults with prediabetes, vitamin D cut the risk of developing type 2 diabetes by 15% over about 3 years and made a return to normal blood sugar 30% more likely.Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes : A Systematic Review and Meta-analysis of Individual …
- An analysis of 15 meta-analyses of trials in women with polycystic ovary syndrome found vitamin D lowered triglycerides, total and LDL cholesterol, but did not change HDL cholesterol, insulin or body mass index.Effect of vitamin D supplementation on lipid profile, and hormonal functions in polycystic ovary syndrome: An umbrella s…
- A network analysis in people with type 2 diabetes found vitamin D was best of the vitamins for lowering HbA1c, with 4,100 to 7,500 IU a day giving the biggest gain in insulin resistance.Network meta-analysis of the effects of combined exercise and vitamin intervention on insulin resistance and related ind…
- A review of 16 reviews covering 250,569 pregnant women found low vitamin D linked to more gestational diabetes, and supplementation in women who already had gestational diabetes reduced some complications in them and their babies.Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic re…
- A review of 8 cohort studies and 11 trials found higher vitamin D status linked to lower type 2 diabetes risk, but supplements did not change blood sugar in people with normal glucose or established diabetes, and improved insulin resistance in two trials of people with glucose intolerance.Vitamin D and type 2 diabetes: a systematic review.
- A systematic review of 76 studies found the evidence on vitamin D in pregnancy too inconsistent and low quality to support firm conclusions about maternal blood pressure or blood sugar outcomes.Vitamin D supplementation in pregnancy: a systematic review.
- In 22,220 older US adults followed for about 5.3 years, 2000 IU of vitamin D3 daily did not significantly reduce type 2 diabetes risk compared with placebo, though pooling with prior trials showed a modest reduction.Vitamin D supplementation vs. placebo and incident type 2 diabetes in an ancillary study of the randomized Vitamin D and…
- In the VITAL trial, baseline blood sugar markers predicted later type 2 diabetes and heart disease, and randomization to vitamin D did not change those associations.Biomarkers of glucose-insulin homeostasis and incident type 2 diabetes and cardiovascular disease: results from the Vita…
- In 307 infertile men, taking 1400 units of vitamin D3 plus 500 mg calcium daily for 150 days lowered fasting insulin and insulin resistance and raised HDL cholesterol compared with placebo.Vitamin D Supplementation Improves Fasting Insulin Levels and HDL Cholesterol in Infertile Men.
- In 243 people with prediabetes given vitamin D and/or 500 mg calcium daily for 24 weeks, insulin secretion rose, and those low in vitamin D improved pancreatic beta-cell function with vitamin D plus calcium.Effect of Vitamin D and/or Calcium Supplementation on Pancreatic β-Cell Function in Subjects with Prediabetes: A Randomi…
- In 239 Italian adults with type 2 diabetes and low vitamin D, six months of vitamin D3 lowered fasting and after-meal glucose and HbA1c compared with placebo, and some patients needed less meds.Vitamin D3 supplementation improves glycemic control in type 2 diabetic patients: Results from an Italian clinical trial…
- In a 12-month placebo-controlled trial of 173 African-American men with prediabetes and low vitamin D, weekly high-dose vitamin D2 raised vitamin D levels but did not improve insulin sensitivity or HbA1c compared with placebo.EFFECT OF HIGH-DOSE VITAMIN D REPLETION ON GLYCEMIC CONTROL IN AFRICAN-AMERICAN MALES WITH PREDIABETES AND HYPOVITAMINOS…
- In 130 adults with type 2 diabetes on a med, vitamin D over 6 months improved HbA1c and lowered advanced oxidation protein products at 3 months with higher doses, but did not significantly change insulin resistance.The Effects of Vitamin D Supplementation on Metabolic and Oxidative Stress Markers in Patients With Type 2 Diabetes: A 6…
- In 100 adults with type 2 diabetes, drinking vitamin D-fortified yogurt twice daily for 12 weeks improved fasting glucose, HbA1c, insulin sensitivity index and blood fats compared with plain yogurt, along with markers of blood vessel lining health.Regular consumption of vitamin D-fortified yogurt drink (Doogh) improved endothelial biomarkers in subjects with type 2 …
- In 100 people with type 2 diabetes, a yogurt drink with vitamin D and calcium for 12 weeks lowered inflammation markers compared with the same drink without vitamin D (both had calcium).Improvement of vitamin D status resulted in amelioration of biomarkers of systemic inflammation in the subjects with typ…
- In 78 overweight or obese adults, taking 1,000 IU of vitamin D3 daily for 12 weeks, with or without magnesium, did not improve glucose, insulin or insulin resistance compared with placebo.Combined vitamin D and magnesium supplementation does not influence markers of bone turnover or glycemic control: A rand…
- In 60 women with gestational diabetes, 1000 mg calcium daily plus vitamin D for 6 weeks lowered caesarean rates (23% vs 63%) and newborn complications compared with placebo.Calcium plus vitamin D supplementation affects pregnancy outcomes in gestational diabetes: randomized, double-blind, pla…
- In 60 women with polycystic ovary syndrome, a combined magnesium, zinc, calcium and vitamin D supplement for 12 weeks lowered insulin, insulin resistance, triglycerides and total cholesterol compared with placebo.A Trial on The Effects of Magnesium-Zinc-Calcium-Vitamin D Co-Supplementation on Glycemic Control and Markers of Cardio-…
- In 60 women with gestational diabetes, a combined magnesium, zinc, calcium and vitamin D supplement for 6 weeks lowered inflammation and oxidative stress markers compared with placebo.The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and p…
- In 49 pregnant women at risk for pre-eclampsia, 500 mg of calcium carbonate plus 200 IU of vitamin D3 daily for 9 weeks lowered fasting blood sugar and triglycerides compared with placebo, but did not change total, HDL or LDL cholesterol.Effect of calcium-vitamin D supplementation on metabolic profiles in pregnant women at risk for pre-eclampsia: a randomi…
- In 44 people treated for diabetic ketoacidosis, sodium phosphate given by infusion (15 mmole once or three times over about 10 hours) raised blood phosphate levels but did not change how long the ketoacidosis lasted, insulin needs, blood sugar fall, or illness and death.Phosphate therapy in diabetic ketoacidosis.
- In 16 adults with type 2 diabetes and low vitamin D, 12 weeks of vitamin D3 (280 mcg daily for 2 weeks, then 140 mcg daily) raised vitamin D levels but did not improve insulin sensitivity or HbA1c compared with placebo; there were only borderline gains in insulin secretion.Effects of 12 weeks high dose vitamin D3 treatment on insulin sensitivity, beta cell function, and metabolic markers in …
- In 14 adults with type 2 diabetes on an energy-restricted diet, about 1200 mg of calcium daily from fat-free milk and other foods for 12 weeks reduced waist size, blood pressure, total and LDL cholesterol more than a lower-calcium phase.Effect of increased calcium consumption from fat-free milk in an energy-restricted diet on the metabolic syndrome and ca…
- Over 24 months, 4000 IU of vitamin D3 daily did not improve insulin sensitivity or insulin-producing cell function in overweight adults with prediabetes overall, though people starting with very low vitamin D levels (below 12 ng/mL) showed a benefit.Effects of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes.
- In 100 Tunisian adults with type 2 diabetes and low vitamin D, three months of vitamin D supplementation raised vitamin D levels but did not significantly improve blood sugar control or insulin resistance.Influence of vitamin D supplementation on glycemic control in type 2 diabetics.
- In a small case-control study of 18 people with type 2 diabetes, lower vitamin D was linked to more microvascular complications such as nerve, eye, and kidney damage.Vitamin D levels and microvascular complications in type 2 diabetes.
- In 11 people with diabetes and 11 without, taking 3 g of calcium lactate with a glucose drink raised insulin release only in those with diabetes, while intravenous calcium had no effect.Insulin secretion after oral calcium load.
- In 8 adults, a high calcium and vitamin D breakfast did not change blood sugar or insulin responses after a later lunch compared with a low-calcium breakfast.Second meal effects of dietary calcium and vitamin D.
- In 2309 dialysis patients with high phosphate, calcium carbonate binders produced no significant difference in cardiovascular events compared with lanthanum carbonate over a median of about 3 years.Effect of Treating Hyperphosphatemia With Lanthanum Carbonate vs Calcium Carbonate on Cardiovascular Events in Patients …
- In 50 people with Cushing's disease who were low in vitamin D, a single large vitamin D3 dose followed by six weeks of treatment improved insulin sensitivity and raised vitamin D levels, compared with their own starting values.Vitamin D Deficiency in Cushing's Disease: Before and After Its Supplementation.
- In 43 dialysis patients with type 2 diabetes, calcium carbonate binders allowed more aortic calcification over 12 months than lanthanum carbonate, mainly in patients with mild calcification at baseline.Evaluation of aortic calcification with lanthanum carbonate vs. calcium-based phosphate binders in maintenance hemodialy…
- A genetic analysis of over 10,000 people in China found no causal link between genetically higher vitamin D levels and type 2 diabetes, prediabetes, or blood sugar measures.Vitamin D, prediabetes and type 2 diabetes: bidirectional Mendelian randomization analysis.
- In a large survey of Hispanic and Latino adults without diabetes, those eating the most vitamin D from food had lower insulin resistance, but their two-hour blood sugar after a glucose drink was higher, and HbA1c showed no link.Vitamin D, Calcium, Magnesium, and Potassium Consumption and Markers of Glucose Metabolism in the Hispanic Community Hea…
- In a national survey of 9939 US adults, those with diabetes ate about 7% more calcium than those without, but overall diets of the two groups did not differ substantially.Dietary intake of adults with and without diabetes: results from NHANES 2013-2016.
- In a Chinese cohort of 5,543 adults followed for about 3.9 years, lower blood vitamin D was not linked to a higher risk of developing type 2 diabetes.25-Hydroxyvitamin D and Incidence of Type 2 Diabetes from a Chinese Cohort Study.
- In a large prospective cohort of pregnant women, those who ate more calcium before and early in pregnancy had a lower risk of gestational diabetes, with women in the top three intake quartiles (about 795 mg per day or more) about 42 percent less likely to develop it than women in the lowest quartile.Risk of gestational diabetes mellitus in relation to maternal dietary calcium intake.
- In 2,160 people in Tehran, higher blood vitamin D levels were linked to lower insulin resistance and better blood sugar measures, though this study did not test supplements.The association of vitamin D levels and insulin resistance.
- In 912 people from western India, low vitamin D was not associated with HbA1c or insulin resistance in either people with type 2 diabetes or non-diabetic controls.Does vitamin D play a significant role in type 2 diabetes?
- In a case-control study of 756 people undergoing colonoscopy, those with colorectal adenomas had lower calcium intake than those without, but the study's main finding concerned insulin and glucose levels, not calcium supplementation or blood sugar outcomes.Insulin resistance, apoptosis, and colorectal adenoma risk.
- In pregnant South African women, vitamin D levels did not change between visits, while some vitamin D metabolites were linked to blood sugar and insulin measures in mixed directions.Longitudinal changes in vitamin D and its metabolites in pregnant South Africans.
- In 235 people with type 2 diabetes, low vitamin D levels were not linked to diabetic eye damage or its severity.Is there any correlation between vitamin D insufficiency and diabetic retinopathy?
- In 234 young Indian military recruits, higher vitamin D was linked to lower fasting blood glucose, but not to insulin resistance, cholesterol, or triglycerides.Vitamin D, body mass composition and metabolic risk factors in healthy young Indians.
- In 227 obese Mexican children and adolescents, those with low vitamin D had higher fasting insulin and insulin resistance than those with sufficient levels.Vitamin D status and its relation to insulin resistance in a Mexican pediatric population.
- In 180 middle-aged adults, low vitamin D was linked to higher odds of type 2 diabetes, but higher vitamin D levels were also associated with higher blood sugar and insulin resistance measures, so the pattern was inconsistent.Association of vitamin D deficiency with insulin resistance in middle-aged type 2 diabetics.
- In 174 adults with prediabetes or normal glucose tolerance, higher levels of vitamin D binding protein were linked to nerve control of the heart and body fat, but this study did not test any vitamin D supplement.Vitamin D binding protein is related to cardiac autonomic function and metabolic status in prediabetes.
- In 170 people with severe obesity awaiting bariatric surgery, calcium intake was not significantly different from recommended levels only in women aged 51 to 70, while many had impaired glucose metabolism, and the study did not test whether calcium improved blood sugar or heart health.Dietary Intakes and Biochemical Parameters of Morbidly Obese Patients Prior to Bariatric Surgery.
- In 127 women with recurrent pregnancy loss, vitamin D levels were not significantly linked to insulin levels or insulin resistance, although women with higher insulin resistance had lower vitamin D.Glucose/insulin metabolism and vitamin D in women with recurrent pregnancy loss.
- In 52 episodes of diabetic ketoacidosis treated with slow intravenous insulin, most patients also received potassium phosphate, but the study had no comparison group and reported no complications, so it cannot show whether the phosphate itself helped.Low-dose intravenous insulin in the treatment of diabetic ketoacidosis.
- In rats fed a high-sugar diet, vitamin D3 lowered blood glucose and improved insulin release during a glucose load, and lab work suggests this works by calming inflammation in insulin-producing cells.Vitamin D protects against high glucose-induced pancreatic β-cell dysfunction via AMPK-NLRP3 inflammasome pathway.
Review Totals and Summary
Members Only1,069 reviews · 94% positive
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Biohacker Summary
Members Only10 of 10 recommend it
Vitamin D is the main ingredient, and the panel leans clearly in favor: most of the ten recommend it or take it themselves, and the rest are neutral with no one speaking against it. They take it because most people are low on it, since sun and food rarely give enough, and they link it to brain and mood, muscle, immune function, bones and long term health. Vitamin D3 is the form named most often, with three of them giving 5000 IU in the morning, and several say to take it with dietary fat for better absorption, while one pairs it with K2 and has done so for over a decade. Several aim for blood levels well above the normal range, with targets ranging from 40 up to 100 ng/mL, and one says it is only worth taking if you are actually low. Calcium and phosphorus were mentioned only in passing as food nutrients and are smaller ingredients in this product.
See all 10 biohackers →Hide the biohackers
Dr. Eric Berg · Vitamin D · neutral
- Lists Vitamin D as an ingredient found in sardines.
- Lists phosphorus as an ingredient found in sardines.
- States that one can of sardines contains 382 mg of calcium.
- Recommends Vitamin D3 because it's nearly impossible to get enough from food and most people don't get enough sun, advising to aim for blood levels of at least 50 to 80 ng/mL.
- Dr. Berg states that when nutrients like vitamin D are too low, fatigue and weakness can follow.
- Warns against calcium supplements, citing studies that link them to a higher risk of heart attack, especially in postmenopausal women, and suggests getting calcium from dairy instead.
- Recommends focusing on vitamin D3 to support stronger bones if a neck hump is associated with osteoporosis.
- Recommends a minimum of 10,000 IU of vitamin D per day to support natural killer cells.
- Recommends focusing on calcium to support stronger bones if a neck hump is associated with osteoporosis.
- Suggests that increasing vitamin D3 may help address the underlying problem of bruxism.
- Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
- States that magnesium is needed to absorb vitamin D.
- Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
- Warns against calcium carbonate, calling it limestone and the worst source of calcium, stating it takes 12 steps to be converted in the body and is like eating rocks.
Dr. Rhonda Patrick · Vitamin D · neutral
- Notes that vitamin D from sunlight, food, or supplements needs to undergo conversions in the liver and kidneys to become its active hormone form, calcitriol.
- States that Vitamin D supplementation has been associated with a 40% lower dementia risk, and low levels are linked to a 50 to 80% higher risk.
- Recommends getting adequate vitamin D, noting that people taking vitamin D supplements have a 40% lower risk of dementia, while those with lower vitamin D have a 50-80% higher risk.
- Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
- Mentions that vitamin D also plays a role in maintaining muscle mass.
- Recommends ensuring adequate vitamin D intake for men's sperm health.
- Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
- Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
- Mentions that kale delivers calcium, a micronutrient many diets fall short on.
- Notes additional gaps in calcium.
- Reports that alcohol use disorder is associated with a 20-50% greater prevalence of Calcium deficiency.
Thomas DeLauer · Vitamin D · recommends
- Recommends taking Vitamin D3 in the morning, between 6:00 and 10:00 a.m., to align with the body's natural metabolic activation phase and sunlight-triggered vitamin D production.
- Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
- Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
- Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
- Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
- Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
- Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
- Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
- Recommends getting vitamin D, suggesting it can be obtained while walking.
- States that vitamin D is best obtained from the sun, but getting it from food definitely helps, and notes its role as a hormone influencing many cells.
- Recommends D3, suggesting a dose of 2000-4000 IU, and notes that MK-7 slowed bone loss over three years.
- Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
- Explains that eating sardines with their soft bones provides a serious hit of calcium, which is a perfect combination for bones and may contribute to satiety.
- Mentions that magnesium and calcium should not be taken together as they cancel each other out.
Dr. Mark Hyman · Vitamin D · uses
- Consumes Zetopia's Atlantic salmon to get Vitamin D, particularly in the winter months, as it is one of the few foods that provides both Omega-3s and Vitamin D.
- Mentions that the body makes vitamin D from sunlight exposure, and a deficiency can hinder calcium absorption, which is crucial for strong bones.
- Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
- Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Notes that vitamin D plays a role in immune function.
- Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
- Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
- States that vitamin D supplementation can help with oxidative stress.
- Mentions vitamin D as a key nutrient for supporting immune function.
- States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
- Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
- States that green leafy vegetables are great sources of calcium.
- Notes that calcium needs are lower than advertised and that stress, soda, and excess sugar can drive calcium loss.
- Does not prescribe calcium supplements at all, teaching people to get it from whole foods instead, because calcium supplements don't work for building bones or preventing fractures, and it's bone quality, not density, that matters.
Dave Asprey · Vitamin D · uses
- Takes Vitamin DAKE from Suppgrade Labs.
- Suggests that vitamin D supports brain health, muscle function, and focus.
- Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
- States that currently, he is only taking vitamin C and vitamin D.
- Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
- States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
- Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
- Recommends Vitamin D as one of the most important supplements for overall health.
- Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
- Mentions taking vitamin D in the morning, comparing it to the daily dosing of testosterone.
- Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
- Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
- Notes that people take calcium for their bones.
- Warns that taking calcium without vitamin D, A, and K2 can lead to calcium going into tissues, causing bone spurs and other issues, and recommends a two-to-one ratio of calcium to magnesium.
Siim Land · Vitamin D · recommends
- Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
- Recommends taking Vitamin D with fat for better absorption.
- States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
- Lists dairy and sardines as sources of Calcium.
- Thinks vitamin D has some of the strongest evidence and is worth considering.
- Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
- Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
- Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
- Recommends taking Vitamin D in the morning or at lunch with fat.
- Notes that Boron improves vitamin D.
- Notes that Boron reduces calcium/magnesium loss.
- Recommends Vitamin D because microglia contain Vitamin D receptors, and Vitamin D helps keep the immune system properly regulated, with low levels associated with greater neuroinflammation and a higher risk of autoimmune conditions.
- Recommends a high calcium intake for bone health.
- Places calcium supplementation in the 'bad tier' due to its association with increased cardiovascular events, recommending dairy or bones as easier ways to get calcium, though it can be useful for postmenopausal women with low bone density.
Ben Greenfield · Vitamin D · recommends
- Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
- Mentions vitamin D as part of a bare-minimum protocol.
- Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
- Has been taking Vitamin D3 K2 for over a decade.
- Notes that sunlight influences more than just vitamin D production.
- Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
- Recommends getting enough vitamin D for blood pressure management.
- Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
- Recommends using hormone building blocks like vitamin D for hormone optimization.
- Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
- Notes that vitamin D deficiency is the most common deficiency.
- Mentions calcium as a common deficiency.
- Recommends adequate intake of calcium for bone strength.
- Is using calcium chloride mixed with PRP before injecting for the P-shot.
Bryan Johnson · Vitamin D · uses
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
- Takes 5000 IU of Vitamin D3 in the morning for longevity.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Recommends phosphorus as a mineral that, along with calcium, magnesium, and boron, is deposited to fortify the bone structure.
- Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
- Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
Andrew Huberman · Vitamin D · neutral
- Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
- Takes 5000 IU of Vitamin D3 in the morning.
- He takes 5,000 IU of Vitamin D3 in the morning for overall health.
- Takes 5000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 every day for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Discusses "hard water" and the role of magnesium and calcium in cardiovascular health.
Peter Attia · Vitamin D · uses
- Lists vitamin D as one of her staple supplements.
- Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
- States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
- Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
- In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
- Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
- Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
- Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
- Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
- Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
- Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
- Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
- Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
- Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
RAL Summary
Members OnlyTier 2 for Blood Sugar
Several large pooled analyses show vitamin D modestly improves blood sugar and insulin resistance, especially in people low in vitamin D [1][2], and 94% of 1079 reviews are positive.
Take 2 servings a day (6 gummies) to match the dose that worked in the studies.
Where the evidence disagrees: 24 of the 57 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Endocrine system, Metabolic system, Skeletal system
Possible side effects: No major side effects reported.
Supplement Facts
Total Carbohydrates 8 g · Vitamin D 600 IU · Calcium 600 mg
| Calories | 30 | |
| Total Carbohydrates | 8 g | |
| Vitamin D | 600 IU | |
| Calcium | 600 mg | |
| Phosphorus | 290 mg | |
| Sodium | 15 mg |
Other ingredients: Sugar, Glucose Syrup, Pectin, Citric Acid, Natural Colors, Natural Flavors.
Directions: DIRECTIONS: For adults, take three (3) gummies daily, preferably with meals.
Barcode (UPC) 074312503719 · Label source: NIH label database · Report a label change
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Our articles on this subject
- How to Lower Blood Sugar Naturally: A Comprehensive GuideArticle · Sep 9, 2026
- Vitamin D2 vs D3: Which Form Raises Your Vitamin D More?Article · Oct 31, 2026
Graded November 11, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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