Nature's Bounty Co Q-10 100 mg Review
Nature's Bounty Co Q-10 100 mg, 75 Softgels is presented as an antioxidant that supports heart health and is essential for cellular energy production. The page states that it may be especially important for people taking a med medications to take a Co Q-10 supplement, because meds can reduce Co Q-10 levels in the body. The page adds a note that Coenzyme Q-10 is not intended to serve as a replacement for a med therapy, and that a person should not discontinue taking any prescribed medications while supplementing with Coenzyme Q-10. Each serving is one softgel containing 100 mg of Q-Sorb Coenzyme Q-10, and the Daily Value is listed as not established. The container holds 75 servings. The directions say that for adults, one softgel should be taken two times daily, preferably with meals. The product is highlighted with the benefits Supports Cardiovascular Health, Clinically Studied Ingredient, and Q-Sorb. The other ingredients are Rice Bran Oil, Gelatin, and Vegetable Glycerin, and the product contains less than 2 percent of Soy Lecithin and Titanium Dioxide Color. The label is described as Non-GMO and free of artificial flavor, artificial sweetener, sugar, starch, milk, lactose, gluten, wheat, yeast, and fish, and it is sodium free. The warning advises pregnant or nursing people, anyone taking medications, or anyone with a medical condition to consult a doctor before use, to discontinue use and consult a doctor if any adverse reactions occur, and to keep the product out of reach of children. The page instructs that the bottle be stored at room temperature and not used if the seal under the cap is broken or missing. The product is manufactured by Nature's Bounty, Inc. in Bohemia, NY 11716, U.S.A. The FAQ section explains that people should follow the directions on the label, and that anyone wishing to take more than the recommended amount should consult a doctor or other healthcare professional. The page also lists related Co Q-10 options in other strengths, including 400 mg in 39 softgels and 200 mg in 45 softgels, as well as a Fish Oil product. The brand notes that it has offered its products since 1971 and that its products are tested every month.
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Study, Trial or Testing Result Summary
Members Only72 human studies · 43 improved
Each softgel gives 100 milligrams of coenzyme Q10, a full dose that matches the amounts that worked in studies. The largest review of the evidence pooled 26 randomized trials in 1,831 people with heart and metabolic conditions. It found coenzyme Q10 lowered the top blood pressure number by about 4.8 points, with the most benefit at about 100 to 200 milligrams a day [1]. An earlier pooled analysis of 17 trials in 684 people found the top number fell but the bottom number did not change [2]. In a 24-week trial of 101 people with abnormal blood fats, 120 milligrams a day lowered both numbers more than a dummy pill [3]. In a 12-week trial of 83 people whose top number alone was high, 60 milligrams twice a day lowered it by about 18 points [4]. Not every study agrees. A pooled analysis of seven trials in 356 people with diabetes found no change in blood pressure [5]. Two small trials in 50 people with high blood pressure also found no clear change [6]. Overall, the evidence leans toward a modest drop in the top number, mostly in people with heart or metabolic conditions. Animal and cell studies are never counted.
See all 72 studies →Hide the studies
- Across 26 randomized trials of 1,831 people with heart and metabolic conditions, coenzyme Q10 lowered the top blood pressure number by about 4.8 mmHg, with the biggest benefit at roughly 100-200 mg a day.Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A …
- In 16 trials of 1,364 people with acute viral heart inflammation, adding trimetazidine to coenzyme Q10 improved treatment success more than coenzyme Q10 alone over 2-12 weeks; blood pressure was not measured.Combination of trimetazidine and coenzyme Q10 for the treatment of acute viral myocarditis: a systematic review and meta…
- Across 17 randomized trials of 684 people with metabolic diseases, coenzyme Q10 significantly lowered the top blood pressure number but did not significantly change the bottom number.The Effects of Coenzyme Q10 Supplementation on Blood Pressures Among Patients with Metabolic Diseases: A Systematic Revi…
- Across 12 trials of 362 people with high blood pressure, coenzyme Q10 lowered the top number by up to about 17 mmHg and the bottom number by up to about 10 mmHg, with no significant side effects.Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials.
- In seven placebo-controlled trials of 356 people with diabetes lasting at least 12 weeks, coenzyme Q10 did not change blood pressure, though it lowered triglycerides.Effects of coenzyme Q10 supplementation on metabolic profile in diabetes: a systematic review and meta-analysis.
- In trials of people with chronic heart failure taking 60-200 mg a day for 1-6 months, coenzyme Q10 improved the heart's pumping fraction by 3.7%; blood pressure was not reported.The impact of coenzyme Q10 on systolic function in patients with chronic heart failure.
- In three placebo-controlled trials of 96 people with high blood pressure, coenzyme Q10 lowered the top number by 11 mmHg and the bottom by 7 mmHg, though the authors said the studies may be unreliable.Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension.
- In two placebo-controlled trials of 50 people with high blood pressure, coenzyme Q10 did not significantly change the top or bottom blood pressure numbers.Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension.
- Pooling eight placebo-controlled trials in people with congestive heart failure, coenzyme Q10 improved how much blood the heart pumps (stroke volume, cardiac output, ejection fraction), though not exercise work capacity; this is not a blood pressure outcome.Treatment of congestive heart failure with coenzyme Q10 illuminated by meta-analyses of clinical trials.
- Across 14 trials of 1067 mostly older men with heart disease or high blood pressure, coenzyme Q10 improved heart failure outcomes and inflammation markers, but its effects on high blood pressure were inconclusive.Coenzyme Q10 as Adjunctive Therapy for Cardiovascular Disease and Hypertension: A Systematic Review.
- Across eight published trials in high blood pressure, coenzyme Q10 lowered average systolic pressure by 16 mm Hg and diastolic pressure by 10 mm Hg, though the trials were small and varied.Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure.
- This review of recent trials in coronary heart disease found coenzyme Q10 had only less impressive effects on risk factors such as blood pressure, and did not support routine use.Recent Developments in the Role of Coenzyme Q10 for Coronary Heart Disease: a Systematic Review.
- In a randomized trial of 892 adults with hypertension, 100 mg a day of coenzyme Q10 added to standard care for 12 months was followed by fewer non-fatal heart attacks (5.4% vs 8.4%) and fewer fatal heart attacks (1.5% vs 3.1%) than standard care alone.Role of Coenzyme Q10 in Prophylaxis of Myocardial Infarction.
- In 443 healthy elderly people given selenium plus coenzyme Q10 for four years, heart-related deaths over 12 years were lower than with placebo (28.1% vs 38.7%), including in those with high blood pressure.Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A v…
- In 216 older adults with heart failure with preserved ejection fraction, 12 weeks of ubiquinol (600 mg a day) and/or d-ribose improved symptom scores, heart pumping and a heart strain blood marker, but not walking distance; blood pressure was not reported.Effects of Ubiquinol and/or D-ribose in Patients With Heart Failure With Preserved Ejection Fraction.
- In 124 patients with acute viral heart inflammation, coenzyme Q10 lowered inflammation and oxidative stress markers, and combining it with trimetazidine worked better; blood pressure was not reported.Combination Therapy With Coenzyme Q10 and Trimetazidine in Patients With Acute Viral Myocarditis.
- In 105 people with mixed high blood fats on a med, adding 200 mg a day of coenzyme Q10 to omega-3 for 3 months lowered systolic blood pressure, cholesterol and inflammation markers more than a med plus omega-3 alone.Read the study on PubMed (28541926) →
- In 101 people with abnormal blood fats, 120 mg a day of coenzyme Q10 for 24 weeks lowered systolic and diastolic blood pressure more than placebo, and also improved cholesterol and insulin resistance.Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
- In 88 adults with metabolic syndrome, taking coenzyme Q10 for 12 weeks did not change systolic or diastolic blood pressure compared with placebo.Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a rand…
- In 86 women with polycystic ovary syndrome, 8 weeks of coenzyme Q10 or vitamin E, alone or together, lowered systolic blood pressure compared with placebo, and diastolic pressure fell only with the combination.Independent and Additive Effects of Coenzyme Q10 and Vitamin E on Cardiometabolic Outcomes and Visceral Adiposity in Wom…
- In 85 people with moderate-to-severe chronic kidney disease, 200 mg of coenzyme Q10 daily for 8 weeks had no independent effect on blood pressure and increased heart rate, while omega-3 lowered blood pressure.The effects of [omega]3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: a rando…
- In 83 men and women with isolated systolic hypertension, 60 mg of coenzyme Q10 twice daily for 12 weeks lowered systolic blood pressure by an average of 17.8 mm Hg.Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension.
- In 80 people with type 2 diabetes and high cholesterol, 200 mg of coenzyme Q10 daily for 12 weeks lowered systolic blood pressure, but did not significantly improve blood flow in the forearm when taken alone.Combined effect of coenzyme Q10 and fenofibrate on forearm microcirculatory function in type 2 diabetes.
- In 74 adults with type 2 diabetes and dyslipidaemia, 200 mg per day of coenzyme Q10 for 12 weeks lowered systolic blood pressure by about 6 mmHg and diastolic by about 3 mmHg compared with placebo.Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes.
- In 74 people with type 2 diabetes and diastolic heart dysfunction taking 200 mg of coenzyme Q10 daily for 6 months, 24-hour diastolic blood pressure fell compared with placebo, though heart filling did not improve.Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunct…
- In 74 adults with chronic kidney disease taking 200 mg of coenzyme Q10 daily for 8 weeks, blood pressure did not fall more than with placebo, while omega-3 fatty acids did lower it.n-3 fatty acids reduce plasma 20-hydroxyeicosatetraenoic acid and blood pressure in patients with chronic kidney disease…
- In 67 adults with chronic heart failure, a daily 320 mg coenzyme Q10 terclatrate plus creatine combination for 8 weeks raised peak oxygen uptake during exercise more than placebo.Coenzyme Q10 terclatrate and creatine in chronic heart failure: a randomized, placebo-controlled, double-blind study.
- In 65 hemodialysis patients taking 1,200 mg of coenzyme Q10 daily for 4 months, oxidative stress markers fell compared with placebo, but predialysis blood pressure did not change.Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomar…
- In 64 hypertensive adults taking compound fish oil capsules for 3 weeks, blood pressure did not change compared with corn oil, though blood flow in one heart artery improved.Effect of compound fish oil capsules on microvascular function in hypertensive individuals: a triple-blind, randomized, …
- In 60 mildly hypertensive adults, 100 mg daily of coenzyme Q10 for 12 weeks lowered inflammatory markers IL-6 and hs-CRP compared with placebo; the abstract does not report a blood pressure outcome.The Effect of Coenzyme Q10 Supplementation on Pro-Inflammatory Factors and Adiponectin in Mildly Hypertensive Patients: …
- In 60 burn patients, 300 mg a day of coenzyme Q10 for 10 days did not change blood pressure or inflammation compared with placebo, though albumin rose.Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial.
- In 59 hypertensive adults with coronary artery disease taking 60 mg of coenzyme Q10 twice daily for 8 weeks, systolic and diastolic blood pressure fell more than with a B vitamin control, along with lower lipid peroxides.Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary art…
- In 56 patients with weak heart pumping from coronary disease, 300 mg daily of coenzyme Q10 for 8 weeks improved mitochondrial function and blood vessel dilation but did not change blood pressure compared with placebo.Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemi…
- In 54 people with irregular heartbeats, a micronutrient combination containing coenzyme Q10 for 6 weeks reduced heart muscle mass and improved insulin levels compared with placebo, though extra beats were unchanged.Dietary intervention with a specific micronutrient combination for the treatment of patients with cardiac arrhythmias: t…
- In 50 patients with diastolic heart failure, 8 weeks of enalapril plus coenzyme Q10 and vitamin E lowered several hormone levels linked to heart failure, while the abstract does not report a separate effect of coenzyme Q10 alone.[The changes of PRA, ATII, ald, ET and ANP in patients with left ventricular diastolic heart failure and intervention wi…
- In 41 patients with left ventricular dysfunction undergoing bypass surgery, a supplement containing coenzyme Q10 raised heart muscle levels of coenzyme Q10 and reduced left ventricular end-diastolic volume compared with placebo.Nutritional supplementation with MyoVive repletes essential cardiac myocyte nutrients and reduces left ventricular size …
- In 39 older adults with heart failure and preserved pumping function, 4 months of coenzyme Q10 did not significantly improve heart filling measures or NT-proBNP compared with placebo.Coenzyme Q10 in the Treatment of Heart Failure with Preserved Ejection Fraction: A Prospective, Randomized, Double-Blind…
- In 38 children with idiopathic dilated cardiomyopathy, coenzyme Q10 for 6 months improved diastolic heart function more than placebo, with 10 of 17 treated children improving; the dose was not stated.Coenzyme Q10 improves diastolic function in children with idiopathic dilated cardiomyopathy.
- In 32 young kendo athletes, 600 mg of ubiquinol daily for about 11 days during a training camp lowered diastolic blood pressure compared with placebo, but did not reduce exercise-related muscle damage.Effect of reduced coenzyme Q10 (ubiquinol) supplementation on blood pressure and muscle damage during kendo training cam…
- In 30 elderly people with heart failure, a high-dose multi-vitamin and mineral capsule that also contained coenzyme Q10 for 9 months improved heart chamber size, pumping strength and quality of life compared with placebo; the effect of coenzyme Q10 alone cannot be separated out.The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with ch…
- In 30 people with metabolic syndrome and uncontrolled blood pressure on medication, 100 mg of coenzyme Q10 twice daily for 12 weeks did not significantly lower 24-hour blood pressure compared with placebo.A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the…
- In 30 adults with heart failure with preserved ejection fraction, 100 mg of coenzyme Q10 three times daily for 30 days gave no added benefit to heart filling function compared with usual care alone.Effects of coenzyme Q10 supplementation on diastolic function in patients with heart failure with preserved ejection fra…
- In 28 hemodialysis patients randomized to 200 mg per day of coenzyme Q10 for 8 weeks versus placebo in a crossover design, diastolic heart function did not improve significantly compared with placebo.Coenzyme Q10 supplementation and diastolic heart functions in hemodialysis patients: a randomized double-blind placebo-c…
- In 26 healthy young adults, a single 50 mg dose of coenzyme Q10 caused a small, short-lived rise in systolic blood pressure compared with placebo, and had no effect on heart rhythm readings.Electrocardiographic and hemodynamic effects of coenzyme Q10 in healthy individuals: a double-blind, randomized controll…
- In 25 people with a weakened, enlarged heart, about 100 mg of coenzyme Q10 daily for 4 months did not improve heart pumping, heart size, exercise tolerance, or heart rhythm compared with placebo.Ubiquinone (coenzyme Q10) in the long-term treatment of idiopathic dilated cardiomyopathy.
- In 23 adults with heart failure, 300 mg of coenzyme Q10 daily for 4 weeks improved peak oxygen use during exercise and blood vessel function compared with placebo, without side effects.Coenzyme Q10 and exercise training in chronic heart failure.
- In 23 volunteers on a 17-day trek to Everest Base Camp, 300 mg per day of coenzyme Q10 did not prevent the loss of heart muscle mass or the change in diastolic function seen in people without it.Oral Coenzyme Q10 supplementation does not prevent cardiac alterations during a high altitude trek to everest base cAMP.
- In 21 people with heart failure, 100 mg of coenzyme Q10 three times daily for 4 weeks improved heart pumping and muscle contraction compared with placebo, and increased peak oxygen use during exercise.Coenzyme Q10 improves contractility of dysfunctional myocardium in chronic heart failure.
- In 18 adults with chronic kidney disease, 20 mg daily of a mitochondria-targeted ubiquinol for 4 weeks improved blood vessel flexibility compared with placebo, but did not lower central aortic blood pressure.Effects of a mitochondrial-targeted ubiquinol on vascular function and exercise capacity in chronic kidney disease: a ra…
- In 18 male endurance athletes, 28 days of coenzyme Q10 raised blood levels of the nutrient but did not consistently change oxygen uptake, lactate, heart rate or blood pressure during cycling tests compared with placebo.Does exogenous coenzyme Q10 affect aerobic capacity in endurance athletes?
- In patients with heart failure taking 100 mg of ubiquinone daily for 7 months, heart pump measures and symptoms improved.Role of metabolic therapy in cardiovascular disease.
- In 131 people with borderline high blood pressure, a multi-ingredient supplement including coenzyme Q10 for 3 months improved cholesterol and glucose but left blood pressure unchanged.The Effects of a New Generation of Nutraceutical Compounds on Lipid Profile and Glycaemia in Subjects with Pre-hypertens…
- In 104 people with metabolic syndrome, red yeast rice with coenzyme Q10 for 2 months lowered systolic blood pressure by 5.2 and diastolic by 4.9 mmHg versus 3.0 and 2.9 with diet alone.Effect of Monacolin K and COQ10 supplementation in hypertensive and hypercholesterolemic subjects with metabolic syndrom…
- In 66 people with mild high blood pressure and high cholesterol, a daily multi-ingredient tablet containing coenzyme Q10 for 6 months lowered 24-hour systolic blood pressure compared with diet alone; the effect of coenzyme Q10 alone could not be separated out.Nutraceuticals for Serum Lipid and Blood Pressure Control in Hypertensive and Hypercholesterolemic Subjects at Low Cardi…
- In 55 people with congestive heart failure given coenzyme Q in 1976 doses of 30 to 100 mg per day, a mild but stable benefit was seen alongside digitalis, with no significant change in heart rate or blood pressure.A clinical study of the effect of coenzyme Q on congestive heart failure.
- In heart failure patients taking standard medicines, a Pycnogenol and coenzyme Q10 combination for 12 weeks lowered systolic and diastolic blood pressure and increased treadmill walking distance more than in the control group.Investigation of Pycnogenol® in combination with coenzymeQ10 in heart failure patients (NYHA II/III).
- In children with load-induced heart dysfunction, coenzyme Q10 at 3.0 to 3.4 mg per kg daily for 7 days restored normal diastolic (heart relaxation) patterns under stress.Recovery of load-induced left ventricular diastolic dysfunction by coenzyme Q10: echocardiographic study.
- In 30 children with load-induced heart contractility depression, coenzyme Q10 therapy restored a normal heart pumping response to stress (Frank-Starling mechanism).Recovery of the Frank-Starling mechanism by coenzyme Q10 in patients with load-induced contractility depression.
- In a double-blind crossover study of 19 adults with chronic heart muscle disease, 18 reported better activity tolerance with coenzyme Q10 replacement, alongside significant gains in stroke volume and ejection fraction; the dose and duration were not stated.Effective treatment with coenzyme Q10 of patients with chronic myocardial disease.
- In 17 people with congestive heart failure, 30 mg of coenzyme Q10 daily for 6 weeks did not produce a measurable change in heart pumping function, while taurine at 3 g daily did.Usefulness of taurine in chronic congestive heart failure and its prospective application.
- In 424 adults with various heart diseases followed for about 18 months on average, coenzyme Q10 at an average of 242 mg daily was linked to heart function gains, with most patients improving by at least one heart failure class, and no placebo group.Usefulness of coenzyme Q10 in clinical cardiology: a long-term study.
- In 115 people with fatigue, chest pain, or irregular heartbeat and stiff heart muscle, coenzyme Q10 replacement was followed by lower blood pressure in 80% of those with high readings and better heart filling in all patients with follow-up scans, though the study had no placebo group and did not state dose or duration.Isolated diastolic dysfunction of the myocardium and its response to CoQ10 treatment.
- In 30 people with very high triglycerides, 150 mg daily of coenzyme Q10 for 6 weeks lowered blood pressure during fenofibrate treatment in one group and during fish-oil treatment in the other group, with no change in the control group on the other treatments.Possible role of ubiquinone in the treatment of massive hypertriglyceridemia resistant to PUFA and fibrates.
- In 26 adults with high blood pressure, 50 mg of coenzyme Q10 taken twice daily for 10 weeks lowered average systolic blood pressure from about 164 to about 147 mmHg and diastolic from about 98 to about 86 mmHg, with no control group.Coenzyme Q10 in essential hypertension.
- In an open-label study of 17 adults with congestive cardiomyopathy, coenzyme Q10 for 4 months improved functional class by about 20% and heart failure score by 27%, with no placebo group; the dose was not stated.The clinical and hemodynamic effects of coenzyme Q10 in congestive cardiomyopathy.
- In 15 children with dilated cardiomyopathy, 9 months of coenzyme Q10 at about 3.1 mg per kg per day added to usual heart drugs was followed by better heart failure class, but the improvement was not significant after multiple-comparison adjustment and there was no placebo group.The effect of coenzyme Q10 on idiopathic chronic dilated cardiomyopathy in children.
- In 1,191 people with ischemic heart failure, blood coenzyme Q10 levels were not an independent predictor of outcomes, and a med did not worsen outcomes in those with low levels.Read the study on PubMed (20883926) →
- In 109 adults with high blood pressure, an average of 225 mg of coenzyme Q10 daily added to their usual medicines was followed by significantly lower blood pressure and some patients were able to reduce their meds, though there was no control group.Treatment of essential hypertension with coenzyme Q10.
- In 20 children with a genetic coenzyme Q10 deficiency kidney disease, coenzyme Q10 plus a med lowered protein in the urine in five patients, and blood pressure fell over 6 to 12 months after kidney transplant.COQ8B nephropathy: Early detection and optimal treatment.
- In 11 people with moderate to severe heart failure taking standard drugs, 60 mg a day of coenzyme Q10 for about 8 months was followed by better symptoms, better quality of life, and smaller heart chamber measurements.[Efficacy of ubidecarenone in the treatment of patients with cardiac insufficiency].
- In 5 adults with essential hypertension given coenzyme Q10 for 3 to 5 months, blood pressure fell, with the largest drop in one 74-year-old man.Bioenergetics in clinical medicine. VIII. Adminstration of coenzyme Q10 to patients with essential hypertension.
- In patients whose heart filling worsened on a med, coenzyme Q10 supplementation improved diastolic heart function measured by echocardiography.Read the study on PubMed (15541254) →
Review Totals and Summary
Members Only575 reviews · 93% positive
Buyers are largely happy with Nature's Bounty Co Q-10 100 mg softgels, which carry about 575 ratings across the stores that sell them. Most written feedback is positive, with a few clear complaints. This summary covers the softgels only. **What buyers say it did for them:** Many describe steadier energy and better stamina, and some mention workouts. One says, "more steady energy during the day and better recovery after workouts." Others take it for heart reassurance: "It gives me peace of mind about my heart." One calls it "A must for cholesterol management." The Walgreens page adds that people taking meds speak well of it. One reviewer says it stopped their a med-related muscle pain, and another says their doctor recommended it to prevent pain from meds. **What they complain about:** Complaints are few but notable. One reviewer had trouble after taking it: "severe cramps and diarrhea" about an hour after one softgel with food, and they won't buy it again. Another said they never received the supplement. On the Walgreens page, one buyer was surprised to find another supplement included in the product and might return it, while admitting they should have read the information more closely. Another was disappointed they could not buy it in a store and had to order it. **Taste, smell, size and form:** This is a strong point. Reviewers describe small, smooth softgels that are easy to swallow: "Tiny pill thats easy to swallow." Several note no unpleasant aftertaste: "don't have any weird aftertaste." One says there is "no harsh smell when you open" the bottle, and another says it "dissolves easily." The Walgreens summary also notes the softgels are small and easy to swallow. **Value for money:** Price comes up often. One reviewer says, "a good price for an expensive supplement," and another calls it "a great value for the size." On the Walgreens page, value was the most common theme, with several people calling it a good deal given how costly CoQ10 is. One says the 100 mg strength is hard to find from other brands, which keeps them loyal. Reviewers also praised delivery and freshness on that page. **Who it suits and who it didn't:** It seems to suit older adults and people who want a daily heart or energy supplement. One reviewer says, "A must have for us aging folks," and a 72-year-old says they feel really good. People on meds, and those whose doctors recommended CoQ10, also report good experiences. Several say they always rebuy it, and some say they trust the brand's purity and consistency. One buyer wishes they had bought the 200 mg strength instead, though they think 100 mg is probably fine for others. It did not suit the reviewer who had stomach cramps and diarrhea, who also prefers clear vegetarian capsules to softgels so the product's color can be seen. Anyone who checks labels closely should read the ingredient information first, given the buyer surprised by an added supplement.
Biohacker Summary
Members Only7 of 10 recommend it
Eight of the ten panelists spoke about coenzyme Q10, and the group leans positive: four of them say they take it or recommend it, mainly to support the mitochondria, which make the body's energy, and to help with fatigue, heart health and oxidative stress. Doses named range from 100 to 400 mg a day, with 300 mg a day mentioned twice and one panelist suggesting up to 1200 mg for some people, and one advises taking it with a fatty meal, ideally dinner. Three of them point to the ubiquinol form or to forms that absorb better, and one says standard versions are poorly absorbed. Several say meds can lower the body's coenzyme Q10, which is a reason a few take it, though one says good data is lacking that it prevents muscle symptoms from meds, and another says there is no real evidence it extends lifespan. One panelist tried it as part of an energy program and appears to have stopped, and it is also paired with omega-3 and with PQQ by others.
See all 9 biohackers →Hide the biohackers
Dr. Eric Berg · Coenzyme Q10 · neutral
- Mentions that grass-fed liver has coenzyme Q10.
- Recommends that anyone with a med prescription should also take coenzyme Q10, specifically the ubiquinol form, to support heart and muscle function.
- Notes that Merck filed a patent for a med combined with coenzyme Q10, but never added it back into the formula, and that major heart organizations do not recommend taking coenzyme Q10 alongside meds.
- Recommends taking coenzyme Q10, specifically ubiquinol, to prevent the side effects of meds, especially for those experiencing muscle weakness, pain, fatigue, or exercise intolerance. He suggests a dose of 200 to 400 mg, or even up to 1200 mg a day for some individuals.
- Mentions that coenzyme Q10 supports the heart and mitochondria as a powerful antioxidant, and meds deplete its production.
- States that coenzyme Q10 has been known to help people with fibromyalgia feel better.
- Recommends Coenzyme Q10, especially for those on meds, as it's a key nutrient for energy in the mitochondria and works with vitamin E and selenium, and suggests taking it at lunch with a meal.
- Recommends coenzyme Q10 as a remedy for long COVID.
- Mentions that meds block coenzyme Q10 and refers to another video where he discusses it.
- Dr. Berg highlights coenzyme Q10 as a key essential nutrient for mitochondria in the heart, and recommends taking it if on meds, as meds deplete this nutrient.
Dave Asprey · Coenzyme Q10 · uses
- States he takes 300 mg of Coenzyme Q10 every day for 20 years because it is necessary for mitochondria to function and is important for longevity, noting that meds lower it.
- Recommends coenzyme Q10 (CoQ10) to support mitochondria, as it helps generate energy and fights oxidative stress.
- Mentions that there are methylation genes for Coenzyme Q10 that convert it to ubiquinol.
- Suggests taking Coenzyme Q10 to optimize mitochondria.
- Mentions Coenzyme Q10 as something that can change blood viscosity, alongside sunlight and earthing.
- Includes Coenzyme Q10 as a helpful addition to a med protocol.
- Used to give his dog coenzyme Q10 for mitochondrial function.
- Dave Asprey mentions Coenzyme Q10 as something one might take to boost ATP production.
- Dave Asprey mentions that Coenzyme Q10 is a big deal for a lot of people regarding energy.
- Mentions Coenzyme Q10 as one of the micronutrients that can help protect the glycocalyx.
Andrew Huberman · Coenzyme Q10 · uses
- Personally takes Omega-3 and Coenzyme Q10 every day, noting they are known to support cardiovascular health, cellular health and energy, and brain health.
- Personally takes coenzyme Q10 every day, noting it supports cardiovascular health, cellular health, energy, and brain health.
- Discusses a study where probiotics, magnesium orotate, and coenzyme Q10 showed a short-term improvement in symptoms of major depression.
- Discusses Coenzyme Q10 as a fertility supplement.
- Recommends Coenzyme Q10 at 100 to 400 milligrams per day, taken with a meal containing fat, ideally dinner, to improve sperm quality by supporting mitochondrial health, which is vital for sperm formation and fertilization.
- States that coenzyme Q10 should be taken with food.
- Mentions Coenzyme Q10 as a tool for fertility.
- Andrew Huberman says he personally takes AG1's new Omega-3 Coenzyme Q10 product every day, noting that Omega-3 and Coenzyme Q10 are known to support cardiovascular health, cellular health, energy, and brain health.
- Andrew Huberman notes that some papers suggest coenzyme Q10 might be beneficial for egg quality.
Thomas DeLauer · Coenzyme Q10 · uses
- States that coenzyme Q10 is one of his favorite compounds for the mitochondria, and it is found in sardines.
- Recommends getting coenzyme Q10 from good quality red meat and organ meat, or through supplementation, to act as an electron catcher in the mitochondria, optimizing energy production and reducing oxidative stress.
- Recommends utilizing coenzyme Q10 to support mitochondrial function and the electron transport chain, making hydration more effective.
- Recommends coenzyme Q10 as a runner-up for energy and mitochondrial function, explaining it's an electron carrier in the mitochondrial chain that focuses on the last complex, creating a bigger net to catch electrons and reduce oxidative stress.
- Recommends Coenzyme Q10 for fatigue, stating it's essential for electron transport, ATP regeneration, and reducing oxidative stress, and can be found in organ meats, fatty fish, pistachios, and sesame seeds.
- Mentions Coenzyme Q10 as a micronutrient essential for the complex biological workings of metabolism in the mitochondria.
- Recommends 300-600mg of Coenzyme Q10 for those intermittent fasting or on low carb, to help utilize fuel better, support heart health, and strengthen mitochondrial function by improving the proton gradient.
- Recommends Coenzyme Q10 for people who are fasting or on a ketogenic diet, explaining that it helps fuel the electron transport chain, leading to more efficient energy processing and increased energy during OMAD and the eating period.
- Recommends 300 to 600 milligrams of Coenzyme Q10 during the eating period to help the electron transport chain and utilize food for energy.
- Notes that Coenzyme Q10 is good for mitochondrial health and energy, and there's growing evidence linking it to nitric oxide production, suggesting a supplement if one doesn't get enough from meat.
Dr. Mark Hyman · Coenzyme Q10 · recommends
- Mentions that coenzyme Q10 is important in mitochondrial function and can be a factor in migraines.
- Tried coenzyme Q10 as part of a meticulous effort to address energy and metabolism issues, but implies they no longer use it as they were looking for an easier solution.
- Included coenzyme Q10 in a mitochondrial rejuvenation program to support mitochondrial function.
- States that mitochondria need coenzyme Q10 and that PQQ has been shown to work very well with it.
- States that coenzyme Q10 can be very helpful if fatigue is a significant problem, and is a mitochondrial support for energy recovery.
- Recommends Coenzyme Q10 for better mitochondrial function, lower inflammation, improved insulin sensitivity, and blood sugar, especially for those taking meds or experiencing age-related decline in CoQ10 production.
- Takes Coenzyme Q10, believing it affects the mitochondria and the aging process, even without full scientific confirmation.
- Mentions that coenzyme Q10 was part of the mitochondrial therapy that helped a child with autism improve, and later states it is a key component of mitochondrial supplementation.
- Recommends coenzyme Q10 for mitochondrial repair, stating that high doses of 200 to 400 milligrams a day are needed, spread out with food.
- Recommends Coenzyme Q10 for mitochondrial function, especially for fatigue and heart problems, at doses of 200 to 400 milligrams a day, spread out as 100 milligrams three or four times a day with food, noting its safety and effectiveness for conditions like migraine headaches.
Ben Greenfield · Coenzyme Q10 · neutral
- Discusses Coenzyme Q10 as an ingredient that MitoQ uses in a mitochondria-directed form, noting that standard CoQ10 rarely achieves movement past the cell membrane and into mitochondria.
- Discusses Coenzyme Q10 (CoQ10) in the context of MitoQ Pure being an upgraded form of it.
- Is currently using CoQ10 because any type of a med, including natural ones like red yeast rice extract, can deplete the body's coenzyme Q10 levels, affecting mitochondrial health.
- Is a big proponent of crystal-free coenzyme Q10, explaining that most CoQ10 products have poor absorption due to crystallization, and recommends Pharma Nord's patented process for keeping CoQ10 in solution, which achieves three to ten times higher plasma levels.
- Recommends coenzyme Q10 for lung repair, highlighting its importance for mitochondrial and cardiopulmonary function, especially for those exposed to pollution or who have smoked.
- Takes coenzyme Q10 in the morning for heart disease.
- Is currently using CoQ10 because meds, whether prescription or natural like red yeast rice extract, can strip the body of coenzyme Q10 levels.
- Suggests it is smart to include Coenzyme Q10 for reducing fatigue, referencing a systematic review and meta-analysis.
- Believes Coenzyme Q10 is probably beneficial for 80-year-olds with cardiac issues, but not great for most people, as they are not deficient in it when aging starts around 30-35.
- Recommends a stack of Coenzyme Q10, MitoQ, and PQQ for mitochondrial support, noting that supplements stacking all three are available on Amazon.
Siim Land · Coenzyme Q10 · neutral
- Describes Coenzyme Q10 as a mitochondrial supportive supplement that may increase energy production, but notes there isn't actual lifespan or longevity evidence for it.
- Takes 300 milligrams of Coenzyme Q10 daily as a supplement, noting it helps with energy production, fat oxidization, heart health, and longevity.
Peter Attia · Coenzyme Q10 · neutral
- Notes there isn't good data that Coenzyme Q10 prevents a med Associated muscle symptoms, but doesn't object if patients want to take it because it makes them feel better about taking a med.
Dr. Rhonda Patrick · Coenzyme Q10 · neutral
- A daily dose of coenzyme Q10 reduces blood pressure by about 4mmHg systolic and 3mmHg diastolic in people with type 2 diabetes, potentially lowering cardiovascular risk.
RAL Summary
Members OnlyTier 3 for Blood Pressure
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Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system, Metabolic system
Combine with: For heart support, CoQ10 pairs well with magnesium (glycinate or taurate) for blood pressure and rhythm, omega-3 fish oil (EPA/DHA) for triglycerides and vascular health, and L-carnitine for mitochondrial fatty-acid transport. Take CoQ10 with a fat-containing meal to improve absorption of this fat-soluble compound. If you take a med, CoQ10 may help offset depletion. If aging and DNA repair remain your goal, consider adding an NAD+ precursor (NMN or nicotinamide riboside), PQQ for mitochondrial biogenesis, resveratrol or pterostilbene for sirtuin support, and vitamin D3/K2 and a B-complex (folate, B12) for DNA methylation and repair. Consult a healthcare provider first, especially if you take meds like a med or meds, as CoQ10 can interact with them.
Possible side effects: No major side effects were reported in the studies given. The review summary mentions one buyer who had severe cramps and diarrhea after a softgel.
Supplement Facts
Q-Sorb Coenzyme Q-10 100 mg
| Q-Sorb Coenzyme Q-10 | 100 mg | † |
Other ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Contains <2% of.
Directions: Directions: For adults, take one (1) softgel two times daily, preferably with meals.
Barcode (UPC) 074312048869 · Label source: NIH label database · Report a label change
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Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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