NaturesPlus AgeLoss Brain Support Review

AgeLoss Brain Support is presented as a formula for maintaining mental clarity and cognitive vitality as you age. The product is described as combining herbal extracts and cognitive nutrients to help protect brain cells and support mental clarity. The page calls it a go-to formula that delivers a blend of free radical fighters, botanicals and brain-boosting nutrients to help protect the mind and support long-term brain health. The listed benefits include Brain Defense, which the page says supplies key vitamins and nutrients to help neutralize free radicals. A second benefit, the Immunity-Adjusting Botanical Blend, features the FIRST DAY Healthy Immune Response Blend with green tea, turmeric, açai and more. Cellular Health Support is described as helping to maintain healthy brain cell membranes for optimal function. The Cognitive Powerhouse Formula uses CogniPlex, which the page says delivers ginkgo biloba, R-lipoic acid and huperzine-A for memory and focus support. The product is labeled gluten-free and vegetarian. Directions state that, as a dietary supplement for adults, the user should take 2 capsules once daily. The page advises keeping the bottle tightly closed in a cool, dry place. A warning says to keep out of reach of children, and that pregnant or nursing people, or anyone taking medications, should consult a healthcare practitioner before using any herbal product. The bottle shown is 60 count and the page lists 30 servings. The page offers a one-time purchase at $51.95 or a subscribe and save option at $46.76 with a 10 percent saving. Shipping notes mention free ground shipping on orders over $50 and a 30-day satisfaction guarantee. The page also links to a Supplement Facts label and related articles on boosting memory and staying sharp as you age. The supplement facts are not reproduced in the text on this page, so the full ingredient list is not given here. Customers are not shown any written reviews or star ratings on this page.

Product Focus: Focus and MemoryAlso covers:BrainImmune system
Tier ⓘ
Tier 4 · Rank 11
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 11 within Tier 4 for Focus and Memory; 32 of 44 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
48 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
100% of 3
Biohacker Mentions
10 of 10
Cost per month
$104 at 2 servings

Study, Trial or Testing Result Summary

Members Only308 human studies · 114 improved

12 of these 308 human studies gave the ingredient by drip or injection, not by mouth.

308 human studies114 improved126 no effect331,391 people studied

Most of this formula's vitamins and minerals are below the doses used in studies. Zinc reaches a studied dose at two servings a day, but its results for thinking are mixed. A long trial in French adults found better memory with zinc plus other antioxidants [1], while a seven year trial in older adults found no change [2]. Healthy older adults improved on only one of eight memory and attention measures [3]. The 400 mg phospholipid complex has an undisclosed recipe. Some trials of other phospholipid products improved memory [4][5], but soy phosphatidylserine [6] and milk fat phospholipids [7] did not help. Two small studies of a complex antioxidant blend found memory gains [8][9]. It is not clear they tested this exact blend, and this one is only 75 mg. Vitamin C, thiamin, folate and iron are present at low or trace amounts compared with studied doses. Large trials found vitamin E [10] and vitamin B12 [11] did not improve thinking in most people. The inflammation response blend and the ginkgo-based Cogniplex blend have no human studies here. Animal and cell studies are never counted.

See all 308 studies →Hide the studies

Review Totals and Summary

Members Only3 reviews · 100% positive
3 reviews · Vitacost 2 · EBay 1
100% positive0% neutral0% negative

Across the two stores there are 3 ratings in total (2 on Vitacost and 1 on eBay), and the themes below come from the written reviews that could be read on their pages. Only three written reviews were readable in all, so everything here rests on a very small sample and should be treated that way. What buyers praise: All of the written feedback is positive. On Vitacost, a reviewer named Debbie says she and her husband feel AgeLoss Brain Support helps them think more clearly, and that this is why they appreciate it. Another Vitacost reviewer, Sunny29, has used the product for about a year and says the capsules seem to help with overall brain health and to support the immune system. On eBay, a buyer called litman55 left a short message on Apr 22, 2024: "Great item, thank you!" That review is a verified purchase of a new item sold by pricedropper2024, and the only rating on the page is a single 5-star rating. The eBay message praises the item in general terms and says nothing about the capsules' effect, taste, size or packaging. What buyers complain about: No complaints or negative experiences appear in any of the written reviews that could be read. That says little about how common problems might be, given how few reviews there are. Who it seems to suit: The Vitacost reviewers suggest it appeals to people looking for help with mental clarity and general brain health, including a couple who both take it. Sunny29 also mentions immune support as a perceived benefit. Sunny29 has been taking it long term, about a year, and plans to keep buying it through Vitacost, so there is at least one case of repeat purchase. Beyond that, the written feedback gives no detail on who else it might suit. Taste, form and ease of use: Sunny29 describes the capsules as easy to swallow with no aftertaste. This is the only comment on taste or form in the reviews. The eBay review does not mention these points. Value and seller experience: Nothing in the written reviews speaks to price or value. The eBay page also shows seller ratings and buyer comments about the store, but these relate to the seller and shipping rather than to the supplement's quality or effects, so they are not counted as product feedback here. Scope: The reviews read were about the capsules, and no reviews of other forms such as gummies or powder were included in the material, so none had to be left out. In short, the few readable reviews are warm about clearer thinking, easy swallowing, no aftertaste and continued repeat buying, but they are too few to show how customers experience the product more broadly or over time.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Zinc is the main ingredient, and all ten panelists spoke about it, with every one either recommending it or using it. Five take or back it for immune function, mood and neurotransmitters, testosterone, wound healing, gut lining and stomach problems, and a few give doses: 15 mg each morning for longevity, and 30 mg for sperm health. One panelist's pre-surgery plan (a week before and two weeks after) is flagged as a caution, and zinc carnosine is the form named for gut and ulcer support. Panelists pair zinc with vitamin C for immunity, and one says to have enough zinc before trying advanced longevity strategies. Vitamin C was the most discussed of the smaller ingredients in this product, and most who mentioned it back it for collagen and skin, though one panelist stopped their vitamin C serum over its smell.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Zinc · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
    • 30 Oct 2026 · Iron · neutral · YouTube ↗
      Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 24 Oct 2026 · recommends · YouTube ↗
      Recommends taking zinc carnosine for an ulcer or some type of gastric problem.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · recommends · YouTube ↗
      Emphasizes the importance of zinc for decreasing viral replication and recommends taking 40 to 60 mg every single day.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 21 Oct 2026 · Vitamin B1 · recommends · YouTube ↗
      States that taking Vitamin B1 might help with swollen legs and ankles.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that birth control pills deplete the body of zinc, which is needed for the brain to make serotonin.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that birth control pills deplete the body of folate, which is needed for the brain to make serotonin.
    • 19 Oct 2026 · Niacin · recommends · Podcast ↗
      States that expensive NAD+ supplements only turn into $5 niacin in the body and that research has shown niacin can actually raise NAD levels in the blood 5 to 8 times their baseline levels.
    • 18 Oct 2026 · uses · YouTube ↗
      Added zinc to his creatine product because a deficiency in zinc might make creatine not work as well.
    • 18 Oct 2026 · neutral · YouTube ↗
      Mentions that grass-fed liver is loaded with zinc.
  • Andrew Huberman · Zinc · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 19 Oct 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 14 Sep 2026 · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 17 Aug 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 20 Jul 2026 · Iron · recommends · YouTube ↗
      States that Iron is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 15 Dec 2025 · Vitamin B12 · neutral · YouTube ↗
      States that a deficiency in vitamin B12 can be terrible and lead to chronic fatigue-like syndromes, as many parts of mitochondria require B vitamins.
  • Ben Greenfield · Zinc · warns
    • 29 Oct 2026 · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 12 Oct 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as an active form of folate that the body can use directly without conversion.
    • 10 Oct 2026 · recommends · YouTube ↗
      Emphasizes that zinc sufficiency is crucial for immunity because the thymus-derived peptide thymulin, which trains lymphocytes, requires zinc to be active.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 19 Sep 2026 · recommends · YouTube ↗
      Recommends adding zinc into one's stack because it is a co-factor for enzymes involved in testosterone synthesis and sperm maturation, and zinc deficiency is a reproducible cause of low sperm count.
    • 19 Sep 2026 · neutral · Podcast ↗
      He mentions zinc as a supplement with real human data behind it for male fertility.
    • 8 Sep 2026 · neutral · X ↗
      Zinc may support both testosterone and sperm count.
    • 29 Aug 2026 · Niacin · neutral · YouTube ↗
      States that Nrf2 activators, when combined with something like niacin, may have a good effect on plaque progression.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 15 Aug 2026 · warns · YouTube ↗
      Warns that he was taking so much zinc without realizing it because it was in five different things he was taking, and he couldn't pinpoint the problem.
    • 9 Jul 2026 · recommends · YouTube ↗
      Recommends supplementing with zinc if deficient, as multiple trials show significant symptom reduction of tinnitus in zinc-deficient individuals.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
  • Thomas DeLauer · Zinc · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 3 Oct 2026 · neutral · YouTube ↗
      Mentions that more zinc could be beneficial for testosterone, but it's not working on the axis that most people need help with.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares zinc content, noting salmon has under 1mg while oysters have 74mg per 100g, a 70x difference.
    • 18 Sep 2026 · Vitamin C · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 18 Sep 2026 · Iron · neutral · Facebook ↗
      Compares iron content in spinach (2.7mg) and beef (2.6mg), but emphasizes that beef's heme iron absorbs at about 25%, while spinach's non-heme iron absorbs at 2-8%.
    • 6 Sep 2026 · recommends · Instagram ↗
      Recommends keeping zinc levels topped off because it is a critical cofactor for over 300 enzymes and is important for immune cells, testosterone, and wound healing.
    • 5 Sep 2026 · Niacin · uses · YouTube ↗
      Uses niacin as part of their detoxification protocol, taking enough to flush about half an hour before a sauna session.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends 15 mg of supplemental zinc if oysters are not realistic, but emphasizes that food source zinc is better as it comes with natural cofactors like copper and selenium.
  • Dave Asprey · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 3 Sep 2026 · recommends · YouTube ↗
      Emphasizes the importance of having enough zinc before trying advanced longevity strategies like peptides.
    • 1 Sep 2026 · recommends · YouTube ↗
      Suggests that zinc has better safety and protective data than meds for reducing cardio respiratory risk.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
    • 5 Aug 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as a better option than folic acid.
    • 25 Jul 2026 · Vitamin C · neutral · Facebook ↗
      Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
    • 25 Jul 2026 · Niacin · recommends · YouTube ↗
      Recommends niacin, a form of vitamin B3, as one of the two most important raw materials for NAD+ production, found in foods like beef liver, chicken, turkey, and fish, or from supplements.
    • 16 Jul 2026 · Vitamin C · warns · YouTube ↗
      Dave Asprey recommends taking maybe a gram of vitamin C a day in divided doses, noting that plasma levels peak around 250 milligrams twice a day.
    • 14 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Qualia Vitamin C Plus, highlighting its combination of seven forms of vitamin C with 250 mg of citrus bioflavonoids, which helps with absorption and use for building collagen and a strong immune system.
    • 9 Jul 2026 · Vitamin C · warns · YouTube ↗
      Warns that taking too much vitamin C can raise oxalate levels, emphasizing that everything has risk and reward.
    • 1 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      States that Vitamin B12 is extremely important for every kind of brain function and recommends ensuring B12 levels are optimal, around 500, not just barely above normal.
  • Dr. Mark Hyman · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
    • 21 Oct 2026 · Iron · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · recommends · YouTube ↗
      Recommends ensuring adequate zinc intake on a regular basis for immune support, noting some data on zinc lozenges for early cold.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 30 Sep 2026 · Niacin · neutral · YouTube ↗
      Explains that pellagra, which killed 100,000 Americans, was a niacin deficiency, a B vitamin.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with zinc.
    • 14 Sep 2026 · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in zinc, such as pumpkin seeds and oysters, to reduce inflammation.
  • Dr. Rhonda Patrick · Zinc · recommends
    • 29 Sep 2026 · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 28 Sep 2026 · Folate · recommends · YouTube ↗
      Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 21 Aug 2026 · neutral · Instagram ↗
      Discusses findings from a meta-analysis on zinc supplementation, noting it improved insulin resistance, inflammation, and oxidative stress in people with diabetes or prediabetes, and explains its biological role in the pancreas.
    • 5 Jun 2026 · recommends · Instagram ↗
      Recommends nutrients like zinc for men to prioritize sperm mitochondrial health.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 4 May 2026 · Iron · uses · YouTube ↗
      Recently found out he needed to get on an iron supplement and noticed he gets less sore in his training after taking it.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 22 Jan 2026 · Iron · recommends · YouTube ↗
      Advises that menstruating women should ensure they are getting enough iron.
    • 9 Jan 2026 · Vitamin C · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 29 Dec 2025 · Vitamin C · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 17 Dec 2025 · recommends · Instagram ↗
      Recommends Zinc, stating it is a critical mineral required for testosterone production and that supplementation corrects deficiency-related low testosterone.
  • Siim Land · Zinc · recommends
    • 5 Aug 2026 · recommends · YouTube ↗
      States that deficiencies in nutrients such as zinc can impair normal immune regulation.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 14 Oct 2026 · Iron · neutral · Instagram ↗
      Mentions that iron is a mineral necessary for making collagen.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 3 Sep 2026 · Iron · warns · YouTube ↗
      States that excess iron promotes oxidative stress and inflammation, which increases heart disease risk.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
    • 9 Jul 2026 · Vitamin C · neutral · YouTube ↗
      Mentions vitamin C in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
    • 4 Jul 2026 · Vitamin C · uses · YouTube ↗
      Was found to be vitamin C deficient by True Health and Mayo Clinic tests, and now addresses this by eating one extra kiwi fruit daily.
    • 12 Jun 2026 · neutral · YouTube ↗
      Explains that zinc raises testosterone only if zinc status or testosterone levels are low, and can reduce the duration and severity of colds and flu, and lower blood sugar and lipids if zinc status is low.
    • 12 Jun 2026 · Vitamin C · recommends · YouTube ↗
      States that the biggest evidence for multivitamin is that it improves cognition and enhances episodic memory in elderly people, who tend to have worse diets and are more likely to be deficient.
  • Bryan Johnson · Zinc · uses
    • 4 May 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 8 Jul 2026 · Iron · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · Iron · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 14 Apr 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning.
    • 2 Apr 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 5 Jun 2025 · Vitamin B12 · uses · YouTube ↗
      States that Blueprint essential capsules and soft gels are packed with key vitamins and minerals needed for strong bone health.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 16 Dec 2023 · uses · YouTube ↗
      Bryan Johnson's baseline measurements showed low zinc, which was easy to fix by adjusting her protocol and supplements.
    • 26 Sep 2023 · Iron · uses · YouTube ↗
      Takes 10 milligrams of heme iron to get his iron levels up, as they are borderline.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • Date not recorded · recommends · Website ↗
      Recommends adequate Zinc for hair health, noting it is in the Blueprint stack.
    • Date not recorded · Iron · recommends · Website ↗
      Recommends adequate Iron for hair health, noting it is in the Blueprint stack.
    • Date not recorded · Vitamin C · recommends · Website ↗
      Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
  • Peter Attia · Zinc · recommends
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 29 Jun 2025 · Niacin · uses · YouTube ↗
      Peter Attia's AVIA Skincare vitamin C serum also contains niacinamide, which is useful to apply to the skin right after washing.
    • 8 Jun 2025 · Iron · recommends · YouTube ↗
      Recommends iron supplements for women of reproductive age who are iron deficient.
    • 9 Sep 2024 · Iron · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as iron, can be a cause of hair loss in women.
    • 9 Sep 2024 · Vitamin B12 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as B12, can be a cause of hair loss in women.
    • 6 Sep 2024 · neutral · YouTube ↗
      Discusses the AREDS formula, which initially included C and beta-carotene with zinc and copper, and later replaced beta-carotene with lutein and zeaxanthin, showing it could delay or reduce the conversion of mild to severe macular degeneration.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
    • 19 Aug 2024 · Folate · recommends · YouTube ↗
      Highlights folate supplementation as a significant practical progress in nutrition science, which has radically reduced spinabifida.
    • 8 Apr 2024 · Iron · neutral · X ↗
      Delves into the crucial yet often overlooked topic of iron and iron deficiency.
    • 8 Apr 2024 · Iron · neutral · YouTube ↗
      Explains that humans consume about 10 to 20 milligrams of iron per day, absorbing roughly 10% of that, which is 1 to 2 milligrams per day, perfectly offsetting the 1 to 2 milligrams lost daily.
    • 8 Apr 2024 · Iron · recommends · Podcast ↗
      Peter emphasizes the importance of consuming an adequate amount of iron daily to prevent deficiency.

RAL Summary

Members OnlyTier 4 for Focus and Memory

Zinc has some human study support for thinking, but results are mixed, most other ingredients are underdosed or in undisclosed blends, and only 3 reviews exist, so evidence is thin [1][2].

Take 2 servings a day (4 capsules) to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 126 of the 308 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system, Immune system

Combine with: If the goal is vision, pair or replace this with an eye-specific formula that provides lutein (10 mg) and zeaxanthin (2 mg) for macular pigment support, plus astaxanthin for eye strain and oxidative stress. Omega-3 DHA/EPA fish oil helps with dry eye and retinal health, and zinc with copper, vitamin C and vitamin E (AREDS2-style) supports long-term macular health. Bilberry or black currant anthocyanins may help with night vision and eye fatigue. If you still want cognitive support, this product can be taken alongside those eye nutrients, and omega-3 DHA benefits both brain and eye health. Consult a healthcare provider before combining supplements, especially if you take meds, since ginkgo and fish oil can affect bleeding.

Possible side effects: No major side effects reported.

Supplement Facts

Vitamin C 20 mg · Thiamin 0.28 mg · Niacin 4 mg NE
Supplement Facts
Serving Size 2 Capsule(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Vitamin C20 mg
Thiamin0.28 mg
Niacin4 mg NE
Folate83 mcg DFE
Vitamin B1212 mcg
Pantothenic Acid1.5 mg
Iron3.5 mg
Zinc2.5 mg
AgeLoss Phospholipid Complex400 mg†
First Day Healthy Inflammation Response Blend210 mg†
Rejuvabolic Full Spectrum Antioxidant Blend75 mg†
AgeLoss Tocotrienol/Tocopherol Complex70 mg†
Cogniplex70 mg†
† Daily Value not established.

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica, Organic Gold Standard Potentiating Nutrients.

Directions: Directions: As a dietary supplement for adults, take 2 capsules once daily.

Barcode (UPC) 097467080119 · Label source: NIH label database · Report a label change

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Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.