NDS Nutrition Pump Fuel® ALL IN Insanity Review
Pump Fuel® ALL IN Insanity is a maximum-strength, all-in-one pre-workout powder. It is sold under the PMD Sports line from Fit Life Brands. Some listings and the name you gave carry the NDS Nutrition branding. It is the top-stimulant tier of the Pump Fuel ALL IN range. The other tiers are Caffeine Free and Medium Stim. Retailer pages say the Insanity tier has 360 mg of caffeine per serving, including 50 mg of time-release zümXR® caffeine, plus yohimbe. The Medium Stim tier has 200 mg. Each tub holds 20 servings. A serving is large, at roughly 49 g. Retail prices run from about $73 to $85. The formula combines several products that are usually bought and stacked separately. Retailer listings give these per-serving amounts: - **Creatine:** 3 g from a five-form blend. The listings name Creatine MagnaPower and Kre-Alkalyn. - **Citrulline malate:** 10 g. - **Agmatine sulfate:** 1 g. - **S7:** 50 mg, a patented blend. - **Beta-alanine:** 5 g. - **Betaine anhydrous:** 4 g. - **BCAAs:** 4 g in a 2:1:1 ratio. - **Taurine:** 1 g. - **Complex carbohydrates:** over 15 g, including Cluster Dextrin. - **Nootropic and energy ingredients:** Nitrosigine, BioPerine, and the stimulants above. I could not verify the full label from the pages I read, so check the tub's supplement facts panel before relying on these numbers. Each ingredient group works through a different mechanism: - **Pump:** Citrulline malate is converted to arginine. That raises nitric oxide, which relaxes blood vessels and increases blood flow to working muscle. Agmatine and Nitrosigine (inositol-stabilized arginine silicate) are included to support this nitric-oxide pathway. - **Strength and power:** Creatine raises phosphocreatine stores. Those stores regenerate ATP during short, heavy efforts, which supports strength, power and reps. - **Endurance:** Beta-alanine raises muscle carnosine. Carnosine buffers hydrogen ions and delays the burn of fatigue. It also causes the harmless tingling known as paresthesia. Betaine may support power output and cell hydration. - **Energy and focus:** The caffeine comes in two forms. Immediate-release caffeine acts quickly by blocking adenosine receptors. The zümXR® caffeine releases over time to extend energy and soften the crash. Yohimbe adds further stimulation. - **Fuel and recovery:** Cluster Dextrin and the other complex carbohydrates provide sustained fuel for training. The BCAAs and taurine support recovery. - **Absorption:** BioPerine (black pepper extract) is included to improve nutrient uptake. The caffeine and yohimbe make this a product for experienced, stimulant-tolerant users. The company's own Insanity copy cautions that it is for extreme, high-stimulant users only. It is not suited to people who are sensitive to stimulants, have cardiovascular conditions, or are pregnant. Anyone with a medical condition should check with a clinician first. It is also not suited to athletes subject to drug testing without a check of the label. Some blends are proprietary, and one independent reviewer criticised this about the older Insanity version.
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Study, Trial or Testing Result Summary
Members Only36 human studies · 11 improved
The label lists 49 grams of citrulline malate, but that matches the size of a full scoop of this all in one pre-workout, so the real citrulline dose is unknown. Other listed ingredients, such as Kre-Alkalyn and Nitrosigine, were not reviewed here. For citrulline malate the studies are mixed. A review of eight trials found that 6 to 8 grams taken before strength training gave about 3 more repetitions than placebo, a small benefit [1]. One trial in 41 men found a single 8 gram dose raised bench press repetitions and cut muscle soreness by 40 percent [2]. In 22 trained men, a week of daily citrulline slightly sped up a cycling test and eased muscle fatigue [3]. A small study without a placebo group found it reduced feelings of fatigue in tired men [4]. However, a review of nine trials found a single dose did not improve endurance [5], and a trial in 12 men found no gain in repetitions or in feelings of energy and fatigue [6]. No reviews were counted for this product. Animal and cell studies are never counted.
See all 36 studies →Hide the studies
- Across nine trials with 158 healthy young adults, a single dose of citrulline did not improve time to exhaustion or time to finish endurance exercise compared with a control.Effects of citrulline on endurance performance in young healthy adults: a systematic review and meta-analysis.
- Across eight trials with 137 people, 6-8 g of citrulline malate taken 40-60 minutes before strength training gave about 3 more repetitions (6.4%) than placebo, a small benefit.Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analy…
- In three studies of foods rich in citrulline within a larger review of 118 studies, no effect on endurance exercise performance was found.Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systema…
- In 41 men, a single 8 g dose of citrulline malate increased bench press repetitions (up to 52.9% more in the last set) and reduced muscle soreness by 40% compared with placebo.Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
- In 32 trained triathletes taking 3 g a day for 9 weeks, citrulline combined with beetroot extract improved Cooper test distance and cortisol balance versus placebo, while citrulline alone did not improve distance and muscle damage markers did not change.Long-Term Combined Effects of Citrulline and Nitrate-Rich Beetroot Extract Supplementation on Recovery Status in Trained…
- In 30 trained male cyclists, 7 days of a blend with 6 g citrulline raised peak power by 11% and time to fatigue by 36% versus placebo, but finish time and average power did not improve.Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise per…
- In 30 basketball players, a single dose of a pre-workout containing 6 g citrulline malate improved jumping, agility and repeated sprint power versus placebo, but not sprinting or aerobic performance.The Effect of Acute Pre-Workout Supplement Ingestion on Basketball-Specific Performance of Well-Trained Athletes.
- In 28 active young men, a single 8 g dose of citrulline malate did not improve cycling time to exhaustion or a 30-second sprint test compared with placebo.Acute citrulline-malate supplementation is ineffective during aerobic cycling and subsequent anaerobic performance in re…
- In 25 trained young men, eight days of 2 g L-citrulline plus 200 mg glutathione raised blood flow 30 minutes after hard running and raised blood citrulline and arginine versus placebo, but the abstract reports no clear gain in run time to exhaustion.The effects of L-Citrulline and Glutathione on Endurance performance in young adult trained males.
- In 24 healthy adults aged 60-70, one month of a drink with 6 g citrulline and 520 mg nitrate lowered blood pressure and raised maximal cycling power by 5.2% versus placebo, with no change in knee extension performance.Effect of chronic nitrate and citrulline supplementation on vascular function and exercise performance in older individu…
- In 24 healthy young adults doing two months of exercise training, a drink with 6 g citrulline and 520 mg nitrate gave a larger gain in knee muscle strength than placebo but no extra gain in maximal aerobic performance.Synergetic Effect of NO Precursor Supplementation and Exercise Training.
- In 22 healthy adults, a single 6 g dose of citrulline taken 1 or 2 hours before exercise did not improve repetitions, time to exhaustion, or aerobic measures compared with placebo.The effect of l-citrulline and watermelon juice supplementation on anaerobic and aerobic exercise performance.
- In 22 trained men, 2.4 g of L-citrulline daily for 7 days plus a dose before the test cut 4-km cycling time by 1.5% versus placebo and eased feelings of muscle fatigue.Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomize…
- In 22 active handball players, 4 weeks of taking citrulline malate (1 g three times daily) during intense training was linked to a larger drop in blood lactate after exercise than placebo, which the authors suggest may help delay fatigue.The Effect of Citrulline/Malate on Blood Lactate Levels in Intensive Exercise.
- In 20 elite rowers, one week of 6 g citrulline plus beetroot extract improved lactate clearance and peak power in a performance test compared with placebo, but other rowing measures did not improve.Impact of a short-term nitrate and citrulline co-supplementation on sport performance in elite rowers: a randomized, dou…
- In 20 healthy moderately active adults, 100 mg/kg per day of L-citrulline for 10 days did not lengthen time to exhaustion compared with placebo.Ergogenic effects of a 10-day L-citrulline supplementation on time to exhaustion and cardiorespiratory and metabolic res…
- In 18 recreationally trained men, citrulline malate taken for 7 days did not change quadriceps muscle power, torque, fatigue rate, or heart rate compared with placebo.Acute and Chronic Citrulline Malate Supplementation on Muscle Contractile Properties and Fatigue Rate of the Quadriceps.
- In 18 elite soccer players, a single 3 g or 6 g dose of citrulline malate did not change physical performance, fatigue, or recovery during a soccer-specific test compared with placebo.The Effect of a Single Dose of Citrulline on the Physical Performance of Soccer-Specific Exercise in Adult Elite Soccer …
- In 16 trained young swimmers, a single dose of citrulline, arginine, and branched-chain amino acids before a high-intensity swim set made them swim faster than placebo.The Effect of Branched-Chain Amino Acids, Citrulline, and Arginine on High-Intensity Interval Performance in Young Swimm…
- In 15 healthy men, a single drink of beetroot juice with 6 grams of citrulline improved blood flow after a blockage but did not change the number of knee extensions to exhaustion compared with placebo.Effects of acute nitric oxide precursor intake on peripheral and central fatigue during knee extensions in healthy men.
- In 14 healthy older men taking 6 g of citrulline daily for seven days, breathing muscle strength, lung function, and breathing muscle oxygenation did not improve compared with placebo, although exhaled nitric oxide rose.Short-Term L-Citrulline Supplementation Does Not Affect Inspiratory Muscle Oxygenation and Respiratory Performance in Ol…
- In 12 taekwondo athletes, a combined amino acid drink taken after the second of three simulated matches helped them keep their reaction times compared with placebo, which declined with placebo.Branched-chain amino acids, arginine, citrulline alleviate central fatigue after 3 simulated matches in taekwondo athlet…
- In 12 recreationally trained adults, a single 8 g dose of citrulline malate before a high-intensity jump and squat circuit did not reduce fatigue or improve peak power or torque compared with placebo.The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants.
- In 12 recreationally trained men, a single 8 g dose of citrulline malate taken 40 minutes before bench press work did not increase total repetitions, muscle swelling, or feelings of energy and fatigue compared with placebo.Acute Effect of Citrulline Malate Supplementation on Upper-Body Resistance Exercise Performance in Recreationally Resist…
- In 12 trained endurance athletes, drinks containing L-citrulline and arginine taken 60 and 30 minutes before cycling to exhaustion did not change time to exhaustion, power output, or lactate compared with placebo water.Effect of different sports drink compositions on endurance performance and substrate oxidation: a randomized, double-bli…
- In 10 healthy men taking 6 g of citrulline daily for seven days, oxygen uptake responded faster during hard cycling and total work in a performance test rose compared with placebo.l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
- In 10 well-trained men, a single 12 gram dose of citrulline malate taken one hour before repeated sprints and a time-to-exhaustion cycling test did not improve performance or acid-base balance compared with placebo.Acute Citrulline-Malate Supplementation and High-Intensity Cycling Performance.
- In 10 healthy university students, a single dose of L-citrulline before maximal cycling did not speed blood lactate clearance, reduce exercise oxygen cost, or extend time to exhaustion compared with placebo.The Effects of L-Citrulline on Blood-Lactate Removal Kinetics Following Maximal-Effort Exercise.
- In a placebo-controlled trial of 9 male tennis players, a single dose of citrulline, arginine and branched-chain amino acids taken one hour before a simulated match kept their hitting accuracy and direction control higher after the match than placebo.Prevention of perceptual-motor decline by branched-chain amino acids, arginine, citrulline after tennis match.
- In 9 untrained young men, a single 6 g dose of citrulline malate before resistance exercise did not change maximum repetitions or muscle recovery over 72 hours compared with placebo.Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men.
- In 9 trained male cyclists, 7 days of 6 g daily L-citrulline produced a 5.2% faster 40 km time trial than maltodextrin placebo, a trend that did not reach statistical significance (p = 0.08), and did not prevent fatigue in a repeated sprint task.One Week of L-Citrulline Supplementation Improves Performance in Trained Cyclists.
- In a placebo-controlled crossover study in people, citrulline malate was reported to speed the liver's ammonia clearance and help the kidneys retain bicarbonate, which the authors linked to less fatigue.Activity of citrulline malate on acid-base balance and blood ammonia and amino acid levels. Study in the animal and in m…
- In 17 healthy young adults, 3 g of L-citrulline taken 3 hours before a treadmill test shortened time to exhaustion compared with placebo, and 9 g over 24 hours also was tested.L-citrulline reduces time to exhaustion and insulin response to a graded exercise test.
- In 12 healthy men, a single 6 g dose of citrulline raised exhaled nitric oxide but did not improve breathing muscle performance or breathing muscle oxygenation compared with placebo.Acute L-Citrulline Supplementation Increases Nitric Oxide Bioavailability but Not Inspiratory Muscle Oxygenation and Res…
- In 18 men complaining of fatigue, 6 g per day of citrulline malate for 15 days reduced the sensation of fatigue and increased the rate of aerobic energy production in exercising forearm muscle compared with before supplementation; no placebo group was used.Citrulline/malate promotes aerobic energy production in human exercising muscle.
- In 18 recreationally resistance trained men and women, a single 8 gram dose of L-citrulline taken one hour before lifting did not change the number of bench press repetitions, lifting power, or muscle oxygen levels compared with placebo.Acute Effect of L-Citrulline Supplementation on Resistance Exercise Performance and Muscle Oxygenation in Recreationally…
Review Totals and Summary
Members Only1 reviews
I found few reviews of the ALL IN version itself. Most feedback is for the closely related Ultra Pump Fuel Insanity, so the themes below come from both. Customers most often praise the energy. Many describe it as strong but smooth, with only mild jitters and no hard caffeine crash afterwards. One long-term user said the energy lasts through the day without a crash. The pump is the other frequent compliment. Buyers call it "insane" and tie it to better workouts. One reviewer said it helps them push for personal records. Reviewers also like the all-in-one design. One said that because it combines ingredients you would normally stack with a pre-workout, the cost balances out. Another said they save it for competition prep and peak training phases. Flavor gets mostly positive comments. Cherry Slush, Strawberry Slam and Tropical Orange Mango are the named favorites, and people say it tastes good with no aftertaste. Mixability is split. Some reviewers say it mixes easily. Others say it does not mix well, and one mentioned powder sliding down undissolved. That is likely because of the roughly 49 g serving, which is large. Some users also notice the tingling from beta-alanine, though they call it mild. The main complaint is price. Reviewers call it very expensive even when they rate it highly. Some say it is worth the money. Others say the cost per scoop is hard to justify when cheaper pre-workouts are available. A critical blogger who tried the older Insanity formula rated its taste and performance below average and called it overpriced. A different reviewer said the pump was strong but the focus ingredients were weaker than in rival products. A minority of buyers were disappointed in the stimulation. One called the stimulant "meh" despite a good pump. Another said a batch seemed weaker than the version they bought at GNC. Another called it one of the worst pre-workouts they had used. Some buyers suggest buying in store because prices are lower there than online. Overall, the feedback praises the pump, the clean-feeling energy and the flavor. It criticises the high price, the bulky serving that is sometimes hard to mix, and uneven perceived potency.
Biohacker Summary
Members Only10 of 10 recommend it
Our biohacker panel has not discussed this product’s ingredients yet.
RAL Summary
Members OnlyTier 4 for Energy
The citrulline malate studies are mixed rather than showing it fails, with a small strength benefit, no endurance benefit and weak fatigue findings, and the label's 49 g figure looks like the whole scoop rather than the citrulline dose. So it is graded Tier 4, as the studies disagree.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 18 of the 36 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Muscular system, Cardiovascular system, Nervous system
Combine with: For its intended energy and performance use, this product pairs well with creatine monohydrate for strength and power, L-citrulline or citrulline malate for pumps and blood flow, and electrolytes (sodium, potassium, magnesium) for hydration during training. L-theanine can smooth out the jittery edge of caffeine, and a protein or BCAA/EAA supplement supports recovery after training. If occasional heartburn is the real concern, look for a separate product designed for fast relief, such as calcium carbonate or magnesium/aluminum hydroxide antacids, or an alginate (sodium alginate) formula that forms a protective raft. Avoid taking caffeinated pre-workouts on an empty stomach or close to bedtime if you are prone to reflux, and consider talking to a healthcare provider if heartburn is frequent.
Possible side effects: No major side effects were reported in the studies. Reviewers mention mild jitters and a mild tingling sensation, which they link to beta-alanine.
Supplement Facts
Vitamin B6 3 mg · Vitamin B12 30 mcg · Choline 200 mg
| Calories | 160 | |
| Total Carbohydrate | 15 g | |
| Vitamin B6 | 3 mg | |
| Vitamin B12 | 30 mcg | |
| Choline | 200 mg | |
| Calcium | 35 mg | |
| Magnesium | 80 mg | |
| Sodium | 90 mg | |
| Potassium | 160 mg | |
| PUMP FUEL ALL IN Blend | 45,880 mg | † |
| Beta|pH Blend | 9,000 mg | † |
| Amino 2:1:1 Blend | 5,000 mg | † |
| Neuro|Focus Blend | 1,450 mg | † |
| Energy|TR Blend | 375 mg | † |
| Glyco|Load Blend | 15,100 mg | † |
| Uptake Compound | 5 mg | † |
Other ingredients: Natural & Artificial Flavor, Potassium Citrate, Sodium Citrate, Sucralose, Calcium Silicate, Vegetable Juice Color (Beet), Acesulfame Potassium, Sunflower Lecithin.
Directions: Mix 1 scoop with 20 fl. oz. of cold water (adjust to desired taste) and consume 30 minutes prior to workout. For best results take on an empty stomach. Limit use to no more than 1 serving (1 scoop) in a 24-hour period. To be used as part of a physical conditioning program.
Barcode (UPC) 811020912170 · Label source: Reverseagelab · Report a label change
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Graded November 10, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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