Provida Labs 5-Way Metabolic Fat Fighter Review

Provida Labs 5-Way Metabolic Fat Fighter is an oral dietary supplement sold in tablets, usually as a 120-count bottle with a serving of 2 tablets. It was a companion product to the Provida Life Sciences "Food Lovers Fat Loss System." The company was founded in 2000 and sells education-based in-home fitness and weight-loss programs. The trademark was filed in 2004 and covers "vitamin and food supplements." That trademark is now cancelled, and the product appears to be discontinued. It survives mainly through resale listings and old forum threads. One reseller listing describes it as accelerating the body's natural fat-burning process "5 different ways." The marketing claims are the only source for the "five ways." I could not find an official retailer page that lists all five. The pitch fits the Food Lovers program's idea of keeping blood sugar steady so the body burns fat rather than stores it. In general, formulas of this type claim to work through five routes: 1. Supporting carbohydrate and glucose handling. 2. Supplying cofactors for energy metabolism. 3. Mildly raising thermogenesis or energy expenditure. 4. Suppressing appetite. 5. Providing antioxidant support. The label data I could find supports only part of this. Nutrition databases list per 2 tablets 300 mg calcium, 50 mg magnesium, 15 mg zinc, 1.5 mg thiamin, 1.7 mg riboflavin, 20 mg niacin, 2 mg vitamin B6 and 4 mcg vitamin B12. The B vitamins act as cofactors in converting food to cellular energy. Magnesium and zinc take part in insulin signalling and enzyme reactions. Calcium has been proposed to play a small role in fat metabolism. Another database describes the formula as containing "antioxidant-rich herbs and spices." A forum user also reported that the tablets contain caffeine, which would explain the appetite-suppressing, mildly thermogenic effect (see the Summary). This is not a drug. It has no proven fat-loss mechanism of its own, and the likely effects are modest. The vitamins and minerals correct small gaps in micronutrient intake. Any stimulant ingredient raises alertness and suppresses appetite. Carb databases list it at 0 calories, 0 g carbs, 0 g fat and 0 g protein per serving. I could not confirm the full ingredient list, the doses of the active botanicals or any clinical trial of the finished product. Any results would most likely come from the accompanying diet and exercise plan, not from the tablets. Anyone sensitive to stimulants, or taking medication, should check the label and talk to a clinician first.

Product Focus: Weight and Metabolism for WomenAlso covers:DigestionBrainHeart
Tier ⓘ
Tier 4 · Rank 2
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 2 within Tier 4 for Weight and Metabolism for Women; 16 of 20 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
41 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
100% of 1
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only283 human studies · 90 improved

1 of these 283 human studies gave the ingredient by injection, not by mouth.

283 human studies90 improved143 no effect259,451 people studied

Green tea extract, the main ingredient, reaches a studied dose at two servings a day. A review of 59 trials found it lowered body weight, body fat percentage and body mass index [1]. In 102 women with belly fat it gave a small weight loss over 12 weeks [2], and it added to the weight and fat loss from exercise in 30 overweight women [3]. Not all studies agree: a trial in 78 obese women found no benefit [4]. Chromium, also at a full dose at two servings, did no better than a dummy pill in dieting women [5] and did not lower weight in women with polycystic ovary syndrome [6]. Zinc at a full dose gave mixed results [7][8]. Guarana is well below the studied dose and was only tested inside herb blends [9]. Magnesium is also below the studied dose [10]. Calcium made little or no difference to weight [11]. The B vitamins have no good evidence for weight loss; vitamin B6 in a vitamin mix did not change weight loss in dieting women [12], and vitamin B12 did not change body fat [13]. Animal and cell studies are never counted.

See all 283 studies →Hide the studies

Review Totals and Summary

Members Only1 reviews · 100% positive
1 reviews · Google Shopping 1
100% positive0% neutral0% negative

Customer feedback on this product is sparse, dated and often tied to the Food Lovers diet it was bundled with. It is not a large pool of verified reviews. The most consistent complaint is about billing, not the tablets. One Ripoff Report author ordered the Food Lovers Diet from a TV commercial and found a bottle of 120 capsules in the package. That customer was then charged $59.95 for an automatic shipment they say they never agreed to. The same customer was angry that the "true price" was only $14.95 for 120 capsules. They also said the company agreed to cancel future shipments only after a partial refund. Related complaints describe the company continuing to ship after customers refused the upsell, and several call the practice deceptive. Reviews of the product itself are mixed and mostly lukewarm. In one forum thread, a user said the pills contain caffeine and curb her hunger. She found that unhelpful because the diet plan requires eating regularly, and she said her coffee already did that job. Other posters were sceptical and dropped the supplement. One said she opted out after reading reviews on WebMD and complained that past supplements had only cost her money. Several said they got what they needed from food, a multivitamin and vitamin D, and felt more active from following the meal plan alone. Broader commentary on the program is similar. A diet-review site says online reports suggest the diet does not work for most people. It adds that people who paired it with another Provida product reported initial weight loss followed by regain once they stopped. The same site notes that the company has many negative reviews, and some reviewers call it a scam. There is little praise for the tablets. Nobody I found reports dramatic fat loss, and there are no recurring comments on taste, pill size or digestive effects. Resale listings are mostly expired stock offered at deep discounts. One seller listed a bottle at $10 and said it retails for $50. A label-quality rating site gave it 83, but that score reflects ingredient disclosure, not efficacy or customer experience. Overall, buyers appreciate the idea of a simple add-on to a meal plan. They are disappointed by the lack of noticeable results, annoyed by the stimulant-driven appetite suppression and angry about aggressive auto-ship billing.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

The panel's statements cover only smaller ingredients in this product, and magnesium drew the most attention, with all ten panelists speaking on it or on zinc. Most of the panel recommends or uses magnesium, mainly for sleep, and also for blood pressure, muscle recovery, stress and workout performance. Preferred forms are glycinate and threonate, with doses of 300 mg, 400 mg, and 400 to 500 mg a day mentioned, and one panelist warned that labels can overstate how much real magnesium is in a supplement, while another said it does not fix waking at night. Magnesium was paired with vitamin D3 and K2 and with electrolytes. Zinc, a smaller ingredient in this product, was recommended or used by several panelists for testosterone, gut lining, immune support with vitamin C, and wound healing, with one taking 15 mg in the morning.

See all 10 biohackers →Hide the biohackers
  • Dr. Mark Hyman · Magnesium · uses
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 7 Oct 2026 · Zinc · uses · YouTube ↗
      Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
    • 5 Oct 2026 · Zinc · recommends · YouTube ↗
      Recommends ensuring adequate zinc intake on a regular basis for immune support, noting some data on zinc lozenges for early cold.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 30 Sep 2026 · Niacin · neutral · YouTube ↗
      Explains that pellagra, which killed 100,000 Americans, was a niacin deficiency, a B vitamin.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 22 Sep 2026 · Zinc · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with zinc.
    • 16 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
    • 14 Sep 2026 · Zinc · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in zinc, such as pumpkin seeds and oysters, to reduce inflammation.
    • 9 Sep 2026 · uses · YouTube ↗
      Has recommended Magnesium Breakthrough from Bio Optimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
  • Dave Asprey · Magnesium · neutral
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 7 Oct 2026 · Zinc · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 3 Sep 2026 · Zinc · recommends · YouTube ↗
      Emphasizes the importance of having enough zinc before trying advanced longevity strategies like peptides.
    • 1 Sep 2026 · Zinc · recommends · YouTube ↗
      Suggests that zinc has better safety and protective data than meds for reducing cardio respiratory risk.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
    • 15 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends adding 300 or 400 mg of magnesium glycinate before bed to improve deep sleep quality, support growth hormone release, and burn visceral fat while asleep.
    • 28 Jul 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 25 Jul 2026 · Niacin · recommends · YouTube ↗
      Recommends niacin, a form of vitamin B3, as one of the two most important raw materials for NAD+ production, found in foods like beef liver, chicken, turkey, and fish, or from supplements.
  • Dr. Eric Berg · Zinc · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
    • 30 Oct 2026 · Magnesium · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 25 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · Magnesium · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Calcium · warns · YouTube ↗
      Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
    • 24 Oct 2026 · recommends · YouTube ↗
      Recommends taking zinc carnosine for an ulcer or some type of gastric problem.
    • 24 Oct 2026 · Magnesium · recommends · Instagram ↗
      Dr. Eric Berg suggests that magnesium could help support deeper, more restful sleep.
    • 24 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Glycinate, noting that the combination of magnesium and glycine is helpful for connective tissue, sleep, and reducing stress.
    • 23 Oct 2026 · recommends · YouTube ↗
      Emphasizes the importance of zinc for decreasing viral replication and recommends taking 40 to 60 mg every single day.
    • 23 Oct 2026 · Magnesium · recommends · Instagram ↗
      Recommends taking magnesium 90 minutes to 2 hours before bedtime to support better sleep.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Suggests that magnesium glycinate can help support the missing 'break pads' on the nervous system, which contribute to constant pain.
    • 22 Oct 2026 · Magnesium · recommends · Podcast ↗
      Taking 400 mg of magnesium glycinate daily may also help support brain health during menopause.
    • 21 Oct 2026 · Magnesium · warns · YouTube ↗
      Warns against magnesium oxide because it is poorly absorbed, with only about 4% absorption, and can cause diarrhea, despite being commonly used in research and supplements due to its low cost.
  • Andrew Huberman · Zinc · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 22 Oct 2026 · Magnesium · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 19 Oct 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 14 Sep 2026 · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 17 Aug 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 7 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · Magnesium · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Zinc · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Chromium · neutral · YouTube ↗
      Mentions chromium as a secondary ingredient in blood sugar control products, along with vanadium and bittermelon extract.
    • 10 Oct 2026 · Zinc · recommends · YouTube ↗
      Emphasizes that zinc sufficiency is crucial for immunity because the thymus-derived peptide thymulin, which trains lymphocytes, requires zinc to be active.
    • 19 Sep 2026 · Zinc · recommends · YouTube ↗
      Recommends adding zinc into one's stack because it is a co-factor for enzymes involved in testosterone synthesis and sperm maturation, and zinc deficiency is a reproducible cause of low sperm count.
    • 19 Sep 2026 · Zinc · neutral · Podcast ↗
      He mentions zinc as a supplement with real human data behind it for male fertility.
    • 8 Sep 2026 · Zinc · neutral · X ↗
      Zinc may support both testosterone and sperm count.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 29 Aug 2026 · Niacin · neutral · YouTube ↗
      States that Nrf2 activators, when combined with something like niacin, may have a good effect on plaque progression.
    • 25 Aug 2026 · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
  • Dr. Rhonda Patrick · Magnesium · neutral
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 29 Sep 2026 · Zinc · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 28 Sep 2026 · Zinc · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 21 Aug 2026 · Zinc · neutral · Instagram ↗
      Discusses findings from a meta-analysis on zinc supplementation, noting it improved insulin resistance, inflammation, and oxidative stress in people with diabetes or prediabetes, and explains its biological role in the pancreas.
    • 10 Aug 2026 · neutral · Facebook ↗
      States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
    • 10 Aug 2026 · recommends · X ↗
      Recommends considering magnesium to improve mood.
    • 28 Jul 2026 · recommends · Facebook ↗
      Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
    • 29 Jun 2026 · neutral · Facebook ↗
      Mentions that kale delivers magnesium, a micronutrient many diets fall short on.
    • 29 Jun 2026 · Calcium · neutral · Facebook ↗
      Mentions that kale delivers calcium, a micronutrient many diets fall short on.
    • 26 Jun 2026 · recommends · Facebook ↗
      Recommends Magnesium, stating it is a cofactor for over 300 biological processes, including DNA repair, energy production, and sleep regulation.
  • Thomas DeLauer · Magnesium · uses
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 23 Oct 2026 · Zinc · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 8 Oct 2026 · Zinc · recommends · Facebook ↗
      Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 3 Oct 2026 · Zinc · neutral · YouTube ↗
      Mentions that more zinc could be beneficial for testosterone, but it's not working on the axis that most people need help with.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 25 Sep 2026 · neutral · Facebook ↗
      Mentions that magnesium in pumpkin seeds relaxes bronchial smooth muscle.
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares magnesium content, stating bananas have 32mg and pumpkin seeds have 156mg per ounce, a 5x difference.
    • 18 Sep 2026 · Zinc · neutral · Facebook ↗
      Compares zinc content, noting salmon has under 1mg while oysters have 74mg per 100g, a 70x difference.
    • 18 Sep 2026 · Calcium · neutral · Facebook ↗
      Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 30 Sep 2026 · Calcium · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 17 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 14 Aug 2026 · Calcium · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 10 Aug 2026 · recommends · YouTube ↗
      Notes that magnesium is important for activating thiamine into its more biologically active form, and a magnesium deficiency can impair blood sugar regulation even with adequate thiamine intake.
    • 5 Aug 2026 · Zinc · recommends · YouTube ↗
      States that deficiencies in nutrients such as zinc can impair normal immune regulation.
    • 26 Jul 2026 · Chromium · recommends · X ↗
      Recommends chromium as a mineral that can lead to better body composition.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 4 May 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 14 Apr 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
    • 2 Apr 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 5 Jun 2025 · Vitamin B12 · uses · YouTube ↗
      States that Blueprint essential capsules and soft gels are packed with key vitamins and minerals needed for strong bone health.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 4 Jan 2026 · Zinc · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 9 Jul 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 6 Jul 2025 · Calcium · neutral · YouTube ↗
      Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
    • 29 Jun 2025 · Niacin · uses · YouTube ↗
      Peter Attia's AVIA Skincare vitamin C serum also contains niacinamide, which is useful to apply to the skin right after washing.
    • 22 Oct 2024 · Calcium · recommends · YouTube ↗
      Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
    • 21 Oct 2024 · Calcium · recommends · YouTube ↗
      Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
    • 9 Sep 2024 · Vitamin B12 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as B12, can be a cause of hair loss in women.
    • 6 Sep 2024 · Zinc · neutral · YouTube ↗
      Discusses the AREDS formula, which initially included C and beta-carotene with zinc and copper, and later replaced beta-carotene with lutein and zeaxanthin, showing it could delay or reduce the conversion of mild to severe macular degeneration.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.

RAL Summary

Members OnlyTier 4 for Weight and Metabolism for Women

Human studies support Vitamin B6 (10 of 19 human studies showed an improvement), but there are not yet enough reviews to confirm it (1). The final check notes: The tier rests on vitamin B6, a trace nutrient at 2 mg whose positive studies are mostly weight gain in underweight people or much higher doses, rather than the main ingredient, green tea extract; with only one review the evidence still supports tier 4.

Take 2 servings a day (4 tablets) to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 143 of the 283 human studies found no effect.

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Members OnlyBody systems · Combine with · Possible side effects

Body systems: Metabolic system, Digestive system, Nervous system, Cardiovascular system

Combine with: For its actual weight management purpose, pair it with fiber such as glucomannan or psyllium for satiety, magnesium for energy metabolism and blood sugar support, and omega-3 fish oil for metabolic health. Berberine or chromium may help support healthy glucose handling. Take it with food and stay hydrated to limit stomach irritation. For fast heartburn relief, use a separate dedicated option such as calcium carbonate antacid, alginate (sodium alginate) raft formulas, or magnesium hydroxide, taken apart from the fat burner. Consult a healthcare provider if heartburn is frequent or persistent.

Possible side effects: The caffeine from green tea and guarana can curb appetite, and guarana raised blood pressure in one study. In a trial of a guarana and ephedra product, 23% of users quit, possibly from side effects.

Supplement Facts

Vitamin B1 1.5 mg · Vitamin B2 1.7 mg · Niacin 20 mg
Supplement Facts
Serving Size 2 Tablet(s)
Amount Per Serving% Daily Value
Vitamin B11.5 mg
Vitamin B21.7 mg
Niacin20 mg
Vitamin B62 mg
Vitamin B124 mcg
Calcium300 mg
Magnesium50 mg
Zinc15 mg
Chromium100 mcg
Green Tea extract204 mg†
Guarana extract63.75 mg†
† Daily Value not established.

Label source: NIH label database · Report a label change

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Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.