Puritan's Pride Vitamin E-Oil Review

Puritan's Pride Vitamin E in an Oil Blend (Item #000810) is a vitamin E oil sold in a 2.5 fl oz oil bottle with a listed potency of 30000 IU. The page describes it as a Vegetarian Formula and as Pure Enough to Take Orally. The product page presents it as an E-Oil that customers can enjoy for its moisturizing benefits: the page states that Vitamin E Oil, in a base of vegetable oils, will nourish and protect the skin with its moisturizing action. Each serving is 5 drops (0.25 mL), and the Supplement Facts panel lists 100 IU of Vitamin E per serving, shown as 333% Daily Value, from dl-Alpha Tocopheryl Acetate. The container holds 296 servings. The directions say that for adults, five drops (0.25 mL) daily, preferably with a meal, may be taken orally or put in water, juice or food. The same directions say that as a moisturizer, the oil can be applied directly to the skin. The other ingredients listed are soybean oil, corn oil, sesame oil, wheat germ oil and lemon oil. The label states that the product contains no artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no yeast, no fish, and is sodium free. The warning section advises pregnant or nursing people, anyone taking medication, anyone planning a medical procedure, and anyone with a medical condition to consult a doctor before use. It says to discontinue use and consult a doctor if adverse reactions or skin sensitivity occur. For skin use, the label says not to apply to broken or irritated skin or areas affected by rashes, and to avoid contact with eyes. It also says not to use on children or animals, to keep out of reach of children, to store at room temperature, and not to use if the outer seal is torn or missing. Puritan's Pride, as described on the page, has been helping families for more than 50 years and says its products are tested or inspected as many as 15 times during manufacturing. The page also offers one-time purchase and subscription options, with a 20 percent discount shown on the listed price.

Tier ⓘ
Tier 4 · Rank 3
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 3 within Tier 4 for Younger-Looking Skin for Women; 34 of 43 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
50 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
91% of 94
Biohacker Mentions
5 of 10
Cost per month
$3

Study, Trial or Testing Result Summary

Members Only29 human studies · 14 improved
29 human studies14 improved11 no effect725 people studied

This product is vitamin E alone, at 45 milligrams per serving, which is above the 10 milligrams used in one supplement study. Every skin benefit found so far comes from products that mix vitamin E with other ingredients, so they do not show what vitamin E alone does. In 72 women aged 35 or older, a daily drink with collagen, vitamin C and a vitamin E complex improved skin hydration, elasticity, roughness and density over 12 weeks more than placebo [1]. In 60 women, a similar collagen drink improved facial collagen structure over 12 weeks [2]. In 50 women, a face serum with vitamin C, vitamin E and raspberry leaf extract improved elasticity, smoothness and wrinkles over 8 weeks compared with the untreated side [3]. In 39 volunteers, 10 milligrams of vitamin E taken with carotenoids and selenium for 12 weeks increased skin density and reduced roughness [4]. In postmenopausal women, a mixed supplement with vitamin E, soy isoflavones, lycopene, vitamin C and fish oil gave shallower wrinkles [5]. After laser treatment for acne scars, a serum with vitamins C and E and ferulic acid improved healing and hydration [6]. None of these studies tested vitamin E alone. Animal and cell studies are never counted.

See all 29 studies →Hide the studies

Review Totals and Summary

Members Only94 reviews · 91% positive
94 reviews · Puritan's Pride 88 · Google 6
91% positive2% neutral7% negative

Buyers are very positive about Puritan's Pride Vitamin E-Oil, which carries about 88 ratings across the stores that sell it. The reviews here are all favorable, and they describe it as a versatile liquid used on skin and lips, on scars, and as a drop-dose supplement for people and pets. Only the liquid is covered below; reviews of other forms (gummies, capsules, powder) were left out. **What buyers say it did for them:** Reviewers use it mainly as a skin product. One long-time user applies it as a day moisturizer on his face and lips, and his wife now does the same. She says "It helps minimize wrinkles in the cold climate" where they live in northern Wisconsin. Another buyer found it "Great for post surgery scar!" A pet owner reports that it "promotes a soft and shiny coat" for their animals. Beyond these, one reviewer simply calls it "Everything you would want in a Vit E application." **What buyers complain about:** The reviews contain no complaints. Nothing negative is raised about the product, its quality, or its delivery. With so few detailed comments, though, problems that other buyers might run into may simply not have been mentioned. **Taste, smell, and form:** The liquid form is a selling point for one reviewer, who calls it a "Very convenient form of Vit E, especially for older people" who have trouble swallowing pills, and for pets. The same reviewer says it is "practically tasteless." On scent, the northern Wisconsin reviewer says it "smells DIVINE," which is a welcome point for something applied to the face and lips. **Value for money:** Value is mentioned only once. The reviewer who gives it to pets says only "a few drops daily" are needed to be effective, which makes it "quite economical." Nobody comments on the price itself. One buyer also praises the "fast shipment" and says the product arrived "just as described." **Who it seems to suit and who it did not:** It seems to suit people who want a simple, single-ingredient oil to use as a facial or lip moisturizer, people caring for a post-surgery scar, and anyone who finds pills hard to swallow. It also suits pet owners looking for a way to add vitamin E to an animal's diet. One long-time user has relied on it for decades, and enthusiastic wording like "BEST Vitamin E Oil AROUND" suggests strong loyalty among regular users. No one reports that it did not suit them, so there is no information here on who should avoid it. **Bottom line:** The feedback is warm and consistent, though thin on detail. If you want a liquid vitamin E for skin, scars, or easy dosing, these reviews give you good reason to try it.

Biohacker Summary

Members Only5 of 10 recommend it
5 of 10 biohackers on our panel recommend it

The panel is split on vitamin E, with no clear majority recommending it, though most of the ten spoke about it. Those in favor take it for protecting cells and skin, for hair health, or as part of a daily multivitamin or a fat soluble vitamin combination, and a few prefer mixed tocopherols or whole food forms with tocotrienols over the plain synthetic kind. Doses were rarely given; one panelist warned against 335 mg right after a workout for people under 50, and another gives his kids a small daily amount. Several raised cautions: avoiding it for a week before surgery because it can thin the blood, worse outcomes at high doses in lung cancer patients, possible prostate cancer and heart risks, blunted workout gains when combined with vitamin C, and one view that a balanced diet makes it unnecessary. No one said they had stopped taking it, but a few steered shoppers toward food sources like nuts, seeds, avocados and vegetables instead.

See all 10 biohackers →Hide the biohackers
  • Ben Greenfield · Vitamin E · neutral
    • 29 Oct 2026 · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 13 Jun 2026 · neutral · X ↗
      Notes a new study indicating that vitamin E is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
    • 13 Jun 2026 · recommends · Podcast ↗
      Recommends Xtendlife's Tocotrienols Vitamin E for cardiovascular, brain, and healthy aging support, noting that research points to tocotrienols over alpha-tocopherol.
    • 22 Nov 2025 · recommends · YouTube ↗
      Recommends whole food vitamin E, explaining that typical supplements only provide alpha-tocopherol, while the whole food complex includes four tocopherols and four tocotrienols, often with selenium at the core.
    • 16 Nov 2025 · warns · Facebook ↗
      Warns against taking 335 mg of vitamin E immediately after a workout for individuals under 50, as it can dull the body's natural adaptation signal.
    • 9 Oct 2025 · warns · YouTube ↗
      Warns that taking a whole bunch of antioxidants like vitamin E after a workout can suppress the body's inflammatory response, which is necessary for benefits like mitochondrial proliferation and satellite cell generation for new muscle.
    • 7 Jun 2025 · recommends · Podcast ↗
      Recommends Hiya's best-selling children's vitamin for kids to get the full-body nourishment they need.
    • 19 Apr 2025 · recommends · YouTube ↗
      Recommends vitamin E as a powerful antioxidant for pollution, and has tripled his antioxidant intake since arriving in India.
    • 3 Apr 2025 · neutral · YouTube ↗
      Explains that vitamin E requires carrier fats for absorption, which is why it's often recommended to take fat-soluble vitamins with food, and 10X Health's microtransporters release vitamin E upon contact with dietary fats.
    • 3 Jan 2025 · recommends · YouTube ↗
      Ben Greenfield recommends the tocotrienol form of vitamin E for lung health and air pollution exposure, as it is more effective than tocopherol and difficult to get sufficient levels from food.
  • Dr. Eric Berg · Vitamin E · neutral
    • 18 Oct 2026 · neutral · YouTube ↗
      Mentions that grass-fed liver has vitamin E.
    • 10 Oct 2026 · warns · Podcast ↗
      Dr. Berg states that synthetic vitamin E may be acceptable for short-term use, but long-term use can contribute to oxidative stress.
    • 3 Oct 2026 · warns · YouTube ↗
      Warns against synthetic vitamin E (dl-alpha-tocopherol) for ongoing maintenance, citing a trial where it increased prostate cancer risk and explaining that it can become a free radical and starve out necessary protective forms of vitamin E.
    • 20 Sep 2026 · recommends · Facebook ↗
      Recommends taking vitamin E to block the effects of grains.
    • 15 Sep 2026 · neutral · Facebook ↗
      Mentions that castor oil contains vitamin E, which is crucial for maintaining skin barrier function.
    • 9 Sep 2026 · neutral · X ↗
      Discusses why tocotrienols are better than regular vitamin E.
    • 14 Aug 2026 · neutral · Facebook ↗
      Dr. Berg mentions that eggs contain Vitamin E.
    • 24 Jun 2026 · recommends · Instagram ↗
      Fat-soluble vitamins like vitamins A, D, E, and K2 are best taken with a meal, making lunchtime an ideal choice.
    • 30 May 2026 · recommends · YouTube ↗
      Recommends the tocotrienols form of vitamin E for various conditions due to their power, and suggests taking it at lunch with a meal.
    • 10 Apr 2026 · warns · Podcast ↗
      Many one-a-day vitamins are unnecessary. They often contain cheap, synthetic ingredients and fillers that do not benefit your health and may even make matters worse.
  • Dave Asprey · Vitamin E · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
    • 18 Aug 2026 · recommends · YouTube ↗
      Recommends Vitamin E as one of the most important supplements for overall health.
    • 12 Aug 2026 · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
    • 19 Jul 2026 · uses · Facebook ↗
      Includes vitamin K2 as a critical ingredient in Vitamin DAKE, stating that the body needs the right fat soluble vitamins for thousands of reactions.
    • 12 Jun 2026 · neutral · Instagram ↗
      Mentions Vitamin DAKE from Suppgrade Labs as a product that combines fat-soluble vitamins D, A, K, and E to work together.
    • 9 Dec 2025 · recommends · YouTube ↗
      Would have added natural forms of vitamin E after hitting his head.
    • 18 Jul 2025 · recommends · YouTube ↗
      Recommends stacking glutathione with vitamin E to help revive oxidized glutathione back to its reduced form.
    • 4 Jun 2025 · warns · YouTube ↗
      Warns against taking 400 IU of synthetic vitamin A (alpha tocopherol) a day, stating it's one of the worst things you can do unless taken with a full spectrum of other tocopherols and tocotrienols.
    • 6 Mar 2025 · neutral · YouTube ↗
      Describes a patient whose pain was resolved by taking Vitamin E and ubiquinol.
    • 28 Jan 2025 · neutral · YouTube ↗
      Mentions a study where topical vitamin E helped protect against hair loss in mice, and suggests it could be a next step for human trials.
  • Dr. Mark Hyman · Vitamin E · neutral
    • 31 Aug 2026 · neutral · YouTube ↗
      Notes that patients who were very malnourished had extremely low vitamin E.
    • 18 Apr 2026 · neutral · Facebook ↗
      Lists Vitamin E as important for cell protection and anti-aging.
    • 1 Apr 2026 · warns · YouTube ↗
      Recommends avoiding Vitamin E for at least a week before surgery because it can thin the blood.
    • 8 Oct 2025 · neutral · YouTube ↗
      Notes that Vitamin E levels are low in Parkinson's patients.
    • 2 Apr 2025 · recommends · YouTube ↗
      Mentions that people are not getting enough vitamin E, which is found in foods like avocados, nuts, and whole grains.
    • 4 Oct 2024 · neutral · YouTube ↗
      Mentions that vitamin E itself is anti-cancer.
    • 27 Sep 2024 · neutral · YouTube ↗
      Dr. Hyman reports that 84% of the population is deficient in vitamin E, attributing this to a lack of whole grains in the diet.
    • 25 Sep 2024 · warns · YouTube ↗
      Notes that traditional medicine might give patients with fatty liver disease vitamin E, but often the wrong kind, and many will advise against it.
    • 30 Aug 2024 · uses · YouTube ↗
      States that Vitamin E is important as an antioxidant, helping with skin healing, repair, and moisturization, and his favorite is Metagenics E Complex, which contains a mixture of tocopherols.
    • 23 Aug 2024 · recommends · YouTube ↗
      Recommends vitamin E, found in almonds, spinach, olive oil, sunflower seeds, hazelnuts, and avocados, as a great antioxidant.
  • Dr. Rhonda Patrick · Vitamin E · neutral
    • 25 Aug 2026 · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 5 Feb 2026 · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 9 Jan 2026 · neutral · Facebook ↗
      Notes that ~60% of Americans are low in vitamin E.
    • 9 Sep 2025 · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
    • 4 Sep 2025 · neutral · Facebook ↗
      Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory.
    • 11 Aug 2025 · uses · X ↗
      Currently takes the Pure Encapsulations O.N.E Multivitamin.
    • 1 Aug 2025 · neutral · Facebook ↗
      Natural sources of linoleic acid (like nuts, meat, etc.) usually include protective antioxidants (vitamin E) that limit harmful effects.
    • 28 Jul 2025 · warns · Facebook ↗
      Warns that more than 80% of people have low vitamin E levels, unknowingly increasing their risk of heart disease, and even slightly low intake raises oxidized LDL by 8% or more, elevating cardiovascular disease risk.
    • 28 Apr 2025 · warns · YouTube ↗
      Rarely recommends or doses vitamin E due to concerns about its potential to blunt exercise adaptations, especially when combined with vitamin C.
    • 3 Jul 2024 · warns · YouTube ↗
      Reports that alcohol use disorder is associated with a 14-58% greater prevalence of deficiencies in vitamin E.
  • Thomas DeLauer · Vitamin E · neutral
    • 25 Aug 2026 · neutral · YouTube ↗
      Mentions a causal link found between vitamin E and waking up in the middle of the night.
    • 29 Jul 2026 · recommends · YouTube ↗
      Recommends using a multivitamin to ensure adequate micronutrient intake, especially when wholesome food is less available.
    • 9 Jul 2026 · warns · YouTube ↗
      Advises checking multivitamins because many contain 100, 200, or 300% of the daily value of selenium, which can contribute to excessive intake.
    • 26 Jun 2026 · recommends · YouTube ↗
      Recommends vitamin E for protecting skin cell membranes, reducing oxidative stress, and preventing lipid damage, especially for those with high stress and low dietary intake.
    • 6 Jun 2026 · recommends · YouTube ↗
      Recommends taking a multivitamin to ensure adequate intake of important cofactors like B vitamins, magnesium, iron, and zinc, which are essential for the signaling system to be operational.
    • 21 May 2026 · recommends · YouTube ↗
      Recommends Vitamin E for hair graying, as part of a nutrient-dense diet to combat oxidative stress.
    • 20 Apr 2026 · recommends · YouTube ↗
      Mentions vitamin E to a certain degree as a cofactor to support the reversal of hair graying.
    • 10 Apr 2026 · recommends · YouTube ↗
      Recommends a multivitamin stack, specifically Fyhealth, for those who are fasting, as it helps ensure adequate nutrition when calorie and food intake are reduced.
    • 14 Mar 2026 · warns · YouTube ↗
      Warns against synthetic multivitamins, arguing that they are an attempt to be smarter than nature by combining isolated nutrients in proportions not found naturally, and that a whole food approach is superior.
    • 22 Feb 2026 · recommends · YouTube ↗
      Recommends Hiya multivitamins for kids, describing them as monk fruit sweetened chewable vitamins that provide essential vitamins and minerals children might miss in their diet.
  • Siim Land · Vitamin E · neutral
    • 27 Jul 2026 · neutral · YouTube ↗
      Notes that oral vitamin E and C supplementation has been noted to increase the dose of UVB radiation from the sun needed to cause redness of the skin, suggesting increased resilience against sun damage. He also mentions a trial where a combination of slow-release vitamin C and vitamin E decreased the progression of carotid atherosclerosis in men.
    • 9 Jul 2026 · neutral · YouTube ↗
      Mentions vitamin E in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
    • 12 Jun 2026 · recommends · YouTube ↗
      States that the biggest evidence for multivitamin is that it improves cognition and enhances episodic memory in elderly people, who tend to have worse diets and are more likely to be deficient.
    • 24 Apr 2026 · uses · YouTube ↗
      Created Microvitamin, a supplement that bundled all the supplements he was taking, to help fund his a med trial.
    • 12 Feb 2026 · recommends · Instagram ↗
      Recommends Vitamin E from vegetables, fruits, nuts, and seeds for skin protection.
    • 24 Jan 2026 · warns · YouTube ↗
      Mentions that years back, a European study revealed risk factors of vitamin E that only showed up with a sufficiently large study.
    • 28 Dec 2025 · neutral · YouTube ↗
      Places multivitamins in the 'good' tier, noting that while formulations vary and they don't reduce mortality risk, clinical trials show they can help with cognitive function in elderly people, though generally healthy individuals may not gain much.
    • 13 Dec 2025 · warns · YouTube ↗
      Warns against taking vitamin E around training because it can interfere with muscle growth.
    • 8 Nov 2025 · warns · YouTube ↗
      Warns that taking vitamin E and vitamin C together can eliminate the adaptive benefits of exercise, especially in sedentary individuals doing exercise training, because it blunts the upregulation of mitochondrial biogenesis.
    • 31 Oct 2025 · neutral · YouTube ↗
      Mentions that Vitamin E technically lengthens telomeres, but also notes that low vitamin D is linked to cancers, highlighting the complexity of health optimization.
  • Andrew Huberman · Vitamin E · uses
    • 17 Jun 2026 · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 24 Feb 2025 · warns · YouTube ↗
      Warns that high-dose supplementation of Vitamin E, when given to lung cancer patients, led to worse outcomes than control subjects, highlighting that it's not the same as ingesting it in food.
    • 26 Jun 2023 · recommends · YouTube ↗
      Recommends Vitamin E as part of the AREDS2 supplementation for slowing the progression of dry macular degeneration.
    • 15 Feb 2023 · warns · YouTube ↗
      Mentions evidence suggesting that a combination of vitamin C and vitamin E can blunt hypertrophic adaptations because they are anti-inflammatory antioxidants.
    • 11 Apr 2022 · recommends · YouTube ↗
      Recommends Vitamin E, especially mixed tocopherols, to help with high prolactin levels.
    • Date not recorded · warns · Website ↗
      Andrew Huberman does not take vitamin E because it spiked his prostate-specific antigen, which he was told is a known effect among urologists.
    • Date not recorded · uses · Website ↗
      Takes a foundational supplement as a source of vitamin A, in addition to food sources.
  • Peter Attia · Vitamin E · warns
    • 20 May 2024 · warns · YouTube ↗
      Notes that there are some downsides to Vitamin E, including cardiovascular longitudinal risk and prostate cancer, and that discussions are needed with patients, especially those with diabetes or cirrhosis, due to studies indicating increased all-cause mortality depending on the dose.
    • 2 Jul 2023 · warns · YouTube ↗
      Peter Attia, involved in the American Urological Association Peyronie's guidelines, stated that vitamin E is not indicated for Peyronie's disease and should not be given.
    • 26 Jun 2023 · warns · YouTube ↗
      States that American Urological Association guidelines advise against giving vitamin E for Peyronie's disease as it is not indicated.
    • 6 Feb 2020 · neutral · YouTube ↗
      Suggests that taking vitamin E would almost assuredly not be required if one eats a balanced diet.
    • 13 Jan 2020 · warns · YouTube ↗
      Notes that Vitamin E acetate, generally regarded as safe for ingestion, is not safe when heated to a vapor or steam, linking it to the dangers of vaping.
    • 6 Jan 2020 · warns · YouTube ↗
      Mentions a lung cancer trial where patients taking vitamin E did worse, and this can be recapitulated in mice.
    • 22 Dec 2019 · neutral · YouTube ↗
      Notes that vitamin C works better for collagen synthesis when combined with vitamin E.
    • Date not recorded · neutral · Website ↗
      Discusses that while observational studies link vitamin E to cognitive health, clinical trials show no effect on dementia risk, suggesting it might act synergistically with other dietary components.
  • Bryan Johnson · Vitamin E · recommends
    • Date not recorded · recommends · Website ↗
      Recommends adequate Vitamin E for hair health, noting it is in the Blueprint stack.
    • Date not recorded · uses · Website ↗
      Uses Vitamin E at 10 IU/ML in his custom topical hair formulation.

RAL Summary

Members OnlyTier 4 for Younger-Looking Skin for Women

Every study counted as an improvement tested vitamin E mixed with collagen, vitamin C, carotenoids, selenium or other ingredients, not vitamin E alone, while vitamin E on its own showed no benefit, so the evidence for this single-ingredient oil is thin. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 11 of the 29 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Skin

Combine with: For skin and antioxidant support, vitamin E pairs well with vitamin C, which helps regenerate oxidized vitamin E, along with collagen peptides, hyaluronic acid, and astaxanthin or other carotenoids. Selenium and mixed tocopherols/tocotrienols can add complementary antioxidant coverage. If bone health is still your main goal, use a separate bone-specific stack: calcium (citrate or hydroxyapatite), vitamin D3, vitamin K2 (MK-7), magnesium, and optionally boron and collagen. Avoid high-dose vitamin E (above about 400 IU daily) alongside meds or high-dose vitamin K antagonists without medical guidance.

Possible side effects: A vitamin C and E face serum caused mild tingling and tightness in one study. Reviews raised no complaints.

Supplement Facts

Vitamin E 45 mg
Supplement Facts
Serving Size 0.1 mL
Servings Per Container 750
Amount Per Serving% Daily Value
Vitamin E45 mg

Directions: Directions: For adults, take two (2) drops (0.1 mL) daily, preferably with a meal. May be taken orally or put in water, juice or food. As a moisturizer, apply directly to your skin.

Barcode (UPC) 025077027910 · Label source: NIH label database · Report a label change

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Our articles on this subject

Graded November 7, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.