Stonehenge Health Dynamic Hair Energy for Women Add 6 Bottles Review
Hair health starts beneath the scalp, at the follicle, the living structure where every strand originates. The page explains that most people think of hair loss as a surface problem, but the real story is cellular. Hair follicles are among the most metabolically active structures in the body and need significant energy to sustain continuous hair production. When that energy falters, or when scalp hormones, nutrients, or blood flow are off, the hair cycle tips toward shedding. Dynamic Hair Energy for Women is presented as the answer to that process. At its core is the BioActive Growth MultiSystem, a targeted blend designed to support healthy mitochondria in follicle cells so they can function efficiently, generate the energy they need, and help maintain conditions for stronger, fuller-looking hair over time. The page states that the energy in the name is a description of what follicles need to thrive rather than a marketing term. The brand says most hair supplements target one or two causes of shedding, while this formula addresses four: scalp hormonal balance, cellular energy, the right nutrients, and strong blood flow. The product is described as built for women who want to feel vibrant and confident and whose hair no longer feels like their own. Key benefits listed include supporting stronger, fuller-looking hair, visibly reduced hair shedding, promoting hair growth, volume and thickness, and providing follicle nutrition. The suggested use is two capsules once daily with water, with a pro tip to take it with a meal containing healthy fat because many key nutrients are fat-soluble. The label notes a serving size of 2 capsules and 30 servings per container, with a caution not to exceed 2 capsules per day, not intended for children, and advice to consult a healthcare professional if pregnant, nursing, or taking medication. The product is manufactured in the USA, distributed by Stonehenge Health in Newport Beach, CA, and carries a 90-day money-back guarantee. Ingredient highlights include Serevelle saw palmetto, Yuth spermidine, EVNolMax tocotrienol and tocopherol complex, eggshell membrane powder, chastetree berry, horsetail, grape seed, green tea and citrus extracts, plus iron, biotin, zinc and B vitamins. A timeline suggests early changes in weeks 4 to 8 and months 2 to 3, with measurable results around months 3 to 6, and the page notes that individual results may vary.
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Study, Trial or Testing Result Summary
Members Only94 human studies · 37 improved
5 of these 94 human studies gave the ingredient by drip or injection, not by mouth.
Biotin is the one ingredient here at or above a studied dose. A 2025 randomized trial in 105 adults found that 1.25 mg of biotin daily for 90 days reduced hair fall and sped hair growth, with no side effects reported [1]. Results elsewhere are weaker: after weight-loss surgery, 1000 micrograms daily helped only 23% of women low in biotin [2]. Zinc is below the studied dose. In women with polycystic ovary syndrome, 50 mg a day reduced hair loss in 41.7% versus 12.5% on placebo [3]. This product gives 10 mg. Vitamin E is a trace amount. The trial that helped hair used 100 mg of tocotrienols [4]. The niacin studies tested creams and foams on the scalp, not pills [5]. Iron helped mainly in women who were low in iron [6]. Vitamin D studies mostly tested injections or creams [7]. No trial has shown that folate or vitamin B12 pills help hair [8][9]. Saw palmetto, chasteberry, green tea and the other extracts sit in two blends whose amounts are hidden. No studies of these blends were given. Animal and cell studies are never counted.
See all 94 studies →Hide the studies
- Pooled across 102 studies of people with patchy autoimmune hair loss and healthy controls, vitamin D deficiency was far more common in those with hair loss, but no vitamin D was given so this does not show a treatment effect.Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis.
- Across 23 studies with 3374 people with non-scarring hair loss and 7296 healthy controls, those with hair loss had lower vitamin D and more deficiency, but supplementation was not tested directly.Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
- Across 36 studies of 10,029 women, those with nonscarring hair loss had lower ferritin (iron stores) than women without hair loss, and about 21% had very low ferritin, but this did not test iron supplements directly.Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
- Across 34 papers with 4931 people, those with patchy hair loss had lower vitamin D levels and higher odds of deficiency than healthy people, but no vitamin D was tested as a treatment.Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis.
- In 18 studies of 2538 people after weight-loss surgery, 57% had hair loss, and those with lower blood folic acid levels (along with zinc and ferritin, but not iron or vitamin B12) were more likely to lose hair; no folate was given as a treatment.Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
- A pooled analysis of 87 observational studies found vitamin D deficiency was more common in people with alopecia areata, but it did not test whether taking vitamin D helps hair.Comorbidities in alopecia areata: A systematic review and meta-analysis.
- Pooled across 91 studies, people with patchy hair loss had lower blood vitamin D than healthy matched controls, but no vitamin D treatment was tested.Biomarkers in alopecia Areata: A systematic review and meta-analysis.
- Pooled studies showed people with patchy or female pattern hair loss had lower vitamin D levels and more deficiency than controls, but supplementation was not tested and needs further study.Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis.
- A review of 17 studies with 61332 people, mostly women, found higher vitamin D levels were linked to less hair loss, though further research is needed.Assessing the relationship between dietary factors and hair health: A systematic review.
- A review of 16 trials in 768 people with patchy hair loss (alopecia areata) found the evidence does not support taking zinc sulphate by mouth.Systemic treatments for alopecia areata: A systematic review.
- A review of 165 articles on off-label skin uses found evidence that topical vitamin D was ineffective for alopecia areata and for hair loss caused by chemotherapy.Off-label uses of topical vitamin D in dermatology: a systematic review.
- In a review of 30 studies of supplements for hair loss in people without known deficiency, vitamin D3 had only low-quality evidence suggesting it improved hair loss.Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.
- A review of 49 articles suggested vitamin D deficiency may contribute to pattern hair loss and supplements showed potential benefit, but results were not consistent and some studies found no link.Micronutrients and Androgenetic Alopecia: A Systematic Review.
- In a 3-month trial of 450 men with low sperm count, alopecia (hair loss) improved better in groups whose regimen included a vitamin E soft capsule, but vitamin E was given in every group and its effect on hair cannot be separated from the other treatments.[Treating oligospermia patients of Shen-essence deficiency syndrome by 3 different treatment programs: a clinical observ…
- In 200 men with male pattern baldness, daily 1% zinc pyrithione shampoo for 26 weeks gave a modest, sustained rise in hair count versus placebo shampoo, about half the effect of 5% minoxidil.The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
- In 105 adults (97 finished) taking 1.25 mg of plant-derived biotin daily for 90 days, hair fall dropped, hair grew faster by about 0.55 mm a day, and nails and skin elasticity improved, with no side effects reported.The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin,…
- In 83 people with hair loss, a daily multi-ingredient tablet containing iron added to usual hair-loss drugs for 12 weeks gave better photo-rated improvement than drugs alone (50% vs 23% reached a score of 2 or more); iron's separate effect was not tested.Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen i…
- In 75 people with patchy alopecia areata, adding topical vitamin D3 to microneedling gave more hair regrowth than microneedling alone, though bimatoprost worked better right after treatment.Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia ar…
- In 62 men with male pattern hair loss, a foam containing a niacin ester plus other ingredients applied twice daily for 6 months reduced the share of resting-phase hairs more than the vehicle foam, but hair density gains did not differ between groups.Reduction of telogen rate and increase of hair density in androgenetic alopecia by a cosmetic product: Results of a rand…
- In a randomized trial of 60 people with scalp alopecia areata, topical calcipotriol and narrowband UVB both improved hair loss scores and blood vitamin D3 levels after 3 months, while placebo did not.Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
- In 60 adults with patchy alopecia areata, vitamin D3 injected into the bald patches every 4 weeks for up to 3 sessions improved hair regrowth significantly more than saline injections.Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
- In a randomized trial of 60 people with localized alopecia areata, a topical vitamin D analogue combined with a potent a med worked about as well as a superpotent a med alone, with fewer side effects, while tacrolimus gave the least improvement.Comparative evaluation of the efficacy of topical tacrolimus 0.03% and topical calcipotriol 0.005% mixed with betamethas…
- In 50 people with diffuse hair loss, six weekly injections of 5 mg biotin with dexpanthenol from either of two brands reduced hair fall and increased hair density, with no placebo group for comparison.Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, dou…
- In 48 women with polycystic ovary syndrome, 50 mg of zinc daily for 8 weeks reduced hair loss compared with placebo (41.7% vs 12.5%), along with lower excess hair growth and a blood marker of oxidative damage.Effects of Zinc Supplementation on Endocrine Outcomes in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blin…
- In 40 people with pattern hair loss or shedding, a zinc and arginine lotion for 23 weeks reduced hair pulled out and improved hair growth measures compared with placebo lotion.A new combination of molecules for the treatment of androgenetic alopecia and telogen effluvium: a double-blind randomiz…
- In 38 people with hair loss, 100 mg of mixed tocotrienols (a vitamin E form) daily for 8 months raised hair count by 34.5% versus a 0.1% decrease with placebo, though hair weight did not change.Effects of tocotrienol supplementation on hair growth in human volunteers.
- In a randomized trial of breast cancer patients receiving chemotherapy, pretreatment with topical calcipotriol did not reduce chemotherapy-related hair loss compared with vehicle.'Atrophic telogen effluvium' from cytotoxic drugs and a randomized controlled trial to investigate the possible protecti…
- In men and women with self-perceived hair thinning, a scalp shampoo and leave-on regimen containing niacinamide and other ingredients used for 24 weeks reduced hair shedding and increased total hair count compared with a placebo shampoo.Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24-week randomized, double-bli…
- In 116 premenopausal female blood donors with iron deficiency but no anaemia, 16 weeks of iron supplements raised ferritin from 7.12 to 25.2 ng/ml and resolved symptoms including hair loss, compared with retrospective controls; hair loss was one of several symptoms, not the main goal.A pilot iron substitution programme in female blood donors with iron deficiency without anaemia.
- In 60 women with female pattern hair loss, topical niacin derivatives applied for 6 months increased hair fullness on blinded photo analysis more than placebo.A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia.
- In 46 women with diffuse hair loss, daily vitamin B6 injections for 20 to 30 days improved hair condition in a number of women and reduced hair loss, especially the telogenic (resting-phase) type, while calcium pantothenate showed no clear benefit.[Evaluation of vitamin B6 and calcium pantothenate effectiveness on hair growth from clinical and trichographic aspects …
- Women with temporary diffuse hair loss took a multi-nutrient supplement containing folic acid for 180 days and had significant improvement in hair loss, volume, density, shine and strength, but folic acid was not tested on its own and there was no placebo group.Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
- In an open-label study of 1000 adults with pattern hair loss, a micronutrient serum containing niacinamide applied monthly for six months was associated with significant improvements in hair density and hair growth, with no major side effects reported; the study had no control group and the niacinamide dose was not stated.The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males an…
- In 1,000 women with polycystic ovary syndrome and thinning hair, a monthly niacinamide-containing scalp serum given without a control group increased terminal hair counts and hair shaft thickness and reduced fine vellus hair over 6 months.Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label,…
- In 112 people with light diffuse hair loss taking a supplement containing biotin for 12 weeks, hair loss fell by 59% and hair density rose, with 90% of participants perceiving better hair growth and appearance, in an open-label study without a control group.Effectiveness, Tolerability, and Acceptance of a Food Supplement in the Management of Non-Illness-Related Hair Loss and …
- In a single-group trial of 101 breast cancer patients, a daily scalp lotion containing a zinc complex did not prevent chemotherapy-induced hair loss, though hair may have recovered somewhat sooner.The utility of DHL-HisZnNa, a novel antioxidant, against anticancer agent-induced alopecia in breast cancer patients: a …
- In a 12-week retrospective study of 48 people with mild-to-moderate alopecia areata, twice-daily topical calcipotriol produced a total response in 69.2% of patients, with significant reduction in hair loss scores.Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study.
- In 35 women with iron deficiency anemia, 8 weeks of oral ferrous sulfate improved hair loss in 84.2% of those with the symptom, and resolved restless legs and cheilitis.Iron Deficiency in Menstruating Adult Women: Much More than Anemia.
- In a clinic series of 18,918 Asian men with male pattern hair loss treated with a combination that included niacin, digital photos showed improvement after 6 to 12 months, with 96% and 80% of patients reporting satisfaction; the study had no control group and combined several treatments.Androgenetic Alopecia Treatment in Asian Men.
- Among 3028 people with telogen effluvium, 4.4% had low folate, and folate was not tested as a treatment for hair loss.Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 pa…
- In a large retrospective review of 2851 women with telogen effluvium, folic acid deficiency was rare (8 people, 0.6%), and the authors emphasized ferritin and iron deficiency instead; this was not a supplement trial.Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
- In a rural Indian clinic of 1,992 people, recurrent scalp hair loss was one of several signs of vitamin B12 deficiency, and adding vitamin powder to food raised blood levels, but the abstract does not report hair improving.Diagnostic Signs and Symptoms of Cyanocobalamin Deficiency at Rural Setting in India: Novel Method of Supplementation.
- In 973 patients with telogen effluvium, vitamin B12 levels showed no significant relationship with the anagen hair ratio measured by digital phototrichogram.Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Corre…
- Children with alopecia areata had lower vitamin B12 levels (233.5 vs 356.7 pg/mL) than matched healthy controls, and low B12 was an independent risk factor.Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
- In 554 non-anemic French menstruating women, low iron stores (ferritin 20 or less) were linked to recent hair loss, with about twice the odds of reporting it.Non-anemic iron deficiency: correlations between symptoms and iron status parameters.
- Lung cancer patients given 400 mcg folic acid daily with vitamin B12 shots before pemetrexed chemotherapy had hair loss rates similar to those not given the vitamins. Hair loss was a side effect of chemotherapy, not a treatment goal.Efficacies and adverse reactions of modified vitamin supplement programs before pemetrexed chemotherapy as a second-line…
- In a retrospective review of 210 people with female or male pattern hair loss compared with 210 matched healthy people, iron stores (serum ferritin) were lower in the hair loss patients, especially premenopausal women, suggesting iron may play a role in hair loss.Iron plays a certain role in patterned hair loss.
- In a 3-year follow-up of 313 people after weight-loss surgery, hair loss was the most common nutritional symptom, but the abstract reports no hair outcome tied to vitamin B12 supplementation.Pragmatic strategy for vitamin and micronutrient supplementation after metabolic and bariatric surgery.
- In 261 patients followed for 6 months after bariatric surgery, vitamin B12 rose with routine supplementation but showed no consistent link to hair loss, while low iron was the strongest predictor.Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Vers…
- In newborn screening of 246 infants with biotinidase deficiency in Ontario, two children who stopped biotin developed hair loss, along with abnormal gait, skin rashes and developmental delay.Biotinidase deficiency: Spectrum of molecular, enzymatic and clinical information from newborn screening Ontario, Canada…
- Women with hair loss had lower vitamin B12 levels (185.5 vs 258.3 pg/mL) than 100 healthy controls, though this study did not test B12 supplementation.Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormon…
- Serum folate and vitamin B12 levels were similar in 91 people with diffuse hair loss and 74 healthy controls. Folate was measured, not supplemented.The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-…
- Among 156 women who had sleeve gastrectomy, 1000 mcg of biotin daily for 3 months gave little benefit: only 5 of 22 women with biotin deficiency (23%) reported a clear reduction in hair loss, with no significant difference compared with those without deficiency.Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements.
- Folate levels were similar in 68 people with scarring alopecia and 68 healthy controls; folate was measured, not supplemented.Micronutrient levels and thyroid functions in scarring alopecias: Do they play a role in disease pathogenesis?
- Blood folate, vitamin B12 and homocysteine levels were no different between 75 people with alopecia areata and 54 controls; folate was measured, not supplemented.Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in alopecia areata patients.
- In 125 women with androgenetic hair loss, vitamin B12 was abnormal in only 5 percent of women, and B12 was not part of the treatment studied.[Hormonal diagnosis in so-called androgenetic alopecia in the female].
- In 113 people with hair loss after COVID-19, 20.4 percent had vitamin B12 deficiency, but the study did not test whether B12 treatment improved hair.Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
- Blood folate levels were similar in 54 people with diffuse hair loss and 55 healthy people, while ferritin and vitamin D were lower in the hair loss group; folate was not supplemented.Serum ferritin and vitamin D levels should be evaluated in patients with diffuse hair loss prior to treatment.
- In 108 women with diffuse hair loss, folic acid levels were within normal limits and did not relate to hair density or hair-shedding measures. Folate was measured, not supplemented.Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, fe…
- In a retrospective study of 100 people with alopecia areata, folic acid deficiency was one of several factors linked to more hair-loss flare-ups, though the study did not test folate supplements.Evaluating the Effect of the Demographic, Trichoscopic and Laboratory Characteristics on The Recurrence of Alopecia Area…
- In a study of 100 women with non-scarring hair loss, average ferritin (iron store) levels were lower than in the control group (20.47 versus 27.87), with a statistically significant difference; this publication is marked as retracted.The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women.
- In a cross-sectional study of 50 men with male-pattern hair loss compared with 25 healthy men, all of the patients had low folic acid, along with low vitamins B12, D and E; the amount of hair loss did not track with these levels, and no supplement was given.A Cross-sectional Study of Plasma Trace Elements and Vitamins Content in Androgenetic Alopecia in Men.
- In children on valproic acid, hair loss and skin rash improved after daily oral biotin 10 mg, which was given as a supplement to patients with low biotinidase activity.Low serum biotinidase activity in children with valproic acid monotherapy.
- Blood vitamin E levels were not different between 37 people with alopecia and 34 healthy controls, although beta-carotene was lower and lipid peroxidation higher in the alopecia group.Antioxidants and lipid peroxidation status in the blood of patients with alopecia.
- Serum folate levels were no different in 31 people with telogen hair loss and scalp pain than in 30 people with the same hair loss but no pain. Folate was measured, not supplemented.Evaluation of Anxiety and Levels of Serum B12, Folate, TSH, Ferritin, and Zinc in Telogen Alopecia Patients with Trichod…
- People with alopecia areata had lower red blood cell folate than healthy controls, and lower levels went with more extensive hair loss; folate was measured, not supplemented.Evaluation of Serum Homocysteine, High-Sensitivity CRP, and RBC Folate in Patients with Alopecia Areata.
- After bariatric surgery in adolescents, 12 of 61 had temporary hair loss and 5 had folate deficiency.Excellent Short- and Medium-term Result of Bariatric Surgery in Adolescence. A Single Center Study.
- People with alopecia areata, psoriasis or vitiligo had significantly lower blood and tissue vitamin E and PON1 levels than 15 healthy controls.The antioxidant role of paraoxonase 1 and vitamin E in three autoimmune diseases.
- People with alopecia areata had significantly lower serum vitamin E than 30 healthy controls, and this level did not differ by disease severity.Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and…
- In a case-control study of 60 women, those with diffuse hair shedding had much lower ferritin (about 16 vs 60 ng/mL) than women without hair loss, and low ferritin at 30 or below was strongly tied to hair shedding.Iron status in diffuse telogen hair loss among women.
- In 50 people who had weight-loss sleeve surgery, 56% developed hair loss within 6 months, and those with hair loss had lower folic acid levels afterward (about 8 ng/ml lower on average); this was not a supplement trial.Hair Loss After Laparoscopic Sleeve Gastrectomy.
- In 49 patients with advanced cancer given a med, pretreatment serum folic acid did not predict drug tolerance. Hair loss occurred in 4 patients as a drug side effect, and folate was not given as a treatment.Read the study on PubMed (4256007) →
- In 48 men with male-pattern hair loss treated for 4 months with topical minoxidil plus vitamin and mineral corrections, folic acid levels did not separate responders from non-responders. Only zinc levels differed between the groups.Plasma Zinc Levels in Males with Androgenetic Alopecia as Possible Predictors of the Subsequent Conservative Therapy's E…
- Infants fed only hydrolysate formula, which contained little biotin, had low blood biotin, and one of them developed hair loss linked to biotin deficiency.Low serum biotin in Japanese children fed with hydrolysate formula.
- In a review of 25 children with short anagen syndrome, a condition where hair does not grow long, biotin alone or with topical minoxidil was reported to be an effective treatment.Short anagen syndrome: A case series and algorithm for diagnosis.
- Patients taking a med (median 20 mg weekly) with folate supplementation sometimes had hair thinning as a side effect; folate itself was not studied for hair.Read the study on PubMed (11567968) →
- In 14 children with methylmalonic acidemia treated with vitamin B12 and carnitine, the abstract reports general improvement but does not report hair outcomes specifically.[Diagnosis and treatment of methylmalonic acidemia in 14 cases].
- In five men with male pattern hair loss, a topical solution containing 0.2% biotin along with minoxidil and a med was judged successful for all five over 6 months, with moderately thicker hair and higher hair density in photographs.Read the study on PubMed (32023218) →
- In a study of children taking valproic acid, three girls who lost hair had their hair loss disappear within about 3 months of taking 10 mg of biotin daily.Serum biotinidase activity in children treated with valproic acid and carbamazepine.
- Three children with valproic acid-related hair loss and normal blood biotin levels had their alopecia resolve within 3 months of taking 10 mg of oral biotin daily.The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity.
- A genetic analysis (Mendelian randomization) of large Finnish populations suggested that higher alpha-tocopherol levels are linked to lower risk of androgenetic and alopecia areata; this is association evidence, not a supplement trial.Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mende…
- In women taking cyproterone acetate with ethinyl oestradiol for androgen-related hair thinning, serum vitamin B12 fell over 6 months, while serum folic acid and red-cell folate stayed within the normal range. Folate was not given as a supplement.Reduced serum vitamin B12 levels during oral cyproterone-acetate and ethinyl-oestradiol therapy in women with diffuse an…
- In a retrospective review of people with telogen effluvium (a type of temporary hair shedding), the authors highlighted vitamin D, ferritin and zinc deficiencies as common, and did not report folate as a notable finding.Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study.
- In a family study of people with partial biotinidase deficiency, one child who was not initially given biotin developed hair loss, hypotonia and a skin rash, and these resolved after biotin therapy; the abstract does not give the dose or duration.Partial biotinidase deficiency: clinical and biochemical features.
- In primary care patients with alopecia, adding an automatic ferritin test found iron deficiency in about 28% of women, but the study did not test whether iron treatment improved hair.Alopecia and Iron Deficiency: An Interventional Pilot Study in Primary Care to Improve the Request of Ferritin.
- In 30 people with alopecia areata and 31 healthy controls, blood iron was higher in the alopecia group, and the authors concluded that prescribing iron is fruitless for this condition while low zinc and manganese were linked to it.Alopecia Areata Different View; Heavy Metals.
- In 20 cancer patients given doxorubicin chemotherapy, high-dose alpha-tocopherol (vitamin E) did not prevent hair loss; 90% had severe hair loss and 10% moderate.High-dose alpha-tocopherol as a preventive of doxorubicin-induced alopecia.
- A leave-on product containing niacinamide with other ingredients increased the thickness of individual scalp hairs by 2 to 5 micrometers in laboratory testing, which the authors suggest may help thinning hair.A novel cosmetic approach to treat thinning hair.
- A topical adenosine complex containing 2% niacinamide increased hair thickness by 10.32% and hair density by 6.20% after about 4 months in people with male or female pattern hair loss, and minoxidil produced smaller gains in the same study.Hair Thickness Growth Effect of Adenosine Complex in Male-/Female-Patterned Hair Loss via Inhibition of Androgen Recepto…
- A product combining nicotinamide and related forms with a green tea compound increased hair density and growth over 24 weeks in men and women, and in lab tests it boosted energy production in hair-related cells; the abstract gives no participant count or control group.Hair growth enhancement via mitochondrial activation by Mito-activator complex.
- In people with zinc deficiency skin disease, hair changes and hair loss can occur, and severe cases were treated with intravenous or high-dose oral zinc, but the abstract reports no measured hair outcome after treatment.[Zinc deficiency dermatoses. Etiology, clinical aspects and treatment].
- In newborn mice, skin lotion containing ferrous ferric chloride stimulated skin cell growth and hair growth and markedly reduced alopecia hair loss.Ferrous ferric chloride stimulates the skin cell function and hair growth in mice.
- In a mouse study, pups nursed by mothers with low iron delivery in milk developed anemia and hair loss on the trunk, which recovered after weaning; giving the mothers iron by injection improved their pups' anemia and development.Maternal intestinal HIF-2α is necessary for sensing iron demands of lactation in mice.
- In mice, iron nanoparticles made from a Blumea eriantha plant extract pushed hair follicles into the growth phase, though less effectively than the minoxidil control.In vivo and in vitro hair growth-promoting effect of silver and iron nanoparticles synthesized via Blumea eriantha DC pl…
Review Totals and Summary
Members Only111 reviews · 87% positive
The store shows 60 ratings in total, and the themes below come from the written reviews that could be read on its page. Those reviews cover the capsules; no other forms of the product were mentioned, so none had to be left out. The written feedback is overwhelmingly positive, and the most common theme is less shedding. Several reviewers say they noticed less hair in the shower, in their brush and on the floor after a few weeks to a few months of use. They also say their hair feels thicker and healthier. Regrowth is the second big theme. Some buyers with thinning at the part or a bald spot report new growth. One reviewer says a bald spot on the left front of the head was covered after about two months. Another describes new growth where hair had been thinning at the part. One reviewer uploaded before and after photos showing the change around the part. One reviewer had shedding caused by an estrogen blocker after breast cancer treatment. She reports new, healthier hair that now grows lower than her waist. She also mentions stronger nails and healthier skin as added bonuses. Several reviewers were skeptical at first because they had already tried over-the-counter foams and biotin supplements. They say about 90 days of use showed clear results. In general, reviewers report that results took one to three months to appear and came gradually rather than immediately. Anyone expecting a quick change should keep that timeline in mind. Some buyers praise the product as a natural alternative to prescribed medication. A few say a spouse or partner liked it too. Overall, reviewers have a sense that the supplement works for many women. The one caution comes from a store reply to the breast cancer reviewer. Stonehenge Health advises speaking with an oncologist first, because chasteberry is generally avoided by women with a history of breast cancer unless approved. It suggests the men's product instead. This is the only safety point raised in the written feedback, and it matters for anyone with a similar medical history. Few complaints about taste, size or side effects appear in the visible reviews, and the summaries give no detail on value or price. Only the first set of written feedback is shown on the page, so it does not give a full range of critical opinions. The lack of complaints should therefore be read with some care. As for who it seems to suit, the reviewers are mostly women dealing with shedding, thinning at the part or small bald spots. They include women whose shedding followed medical treatment, and people who had not got results from foams or biotin. The product also appeals to those wanting a natural option rather than a prescription. Women with a history of breast cancer should get approval from their oncologist before taking it. In short, the written themes are less shedding, new growth, thicker-looking hair and gradual results over one to three months, with the chasteberry caution as the single safety flag.
Biohacker Summary
Members Only10 of 10 recommend it
The panel is split on biotin, the main ingredient: two of the ten recommend it, for keratin production and stronger hair and for hair follicle health and growth, and one of them points to eggs, almonds and salmon as food sources. Three others warn, and the cautions are different ones: one says biotin is a little overhyped and that enough protein is probably more useful for hair, skin and nails, while two say biotin can interfere with blood tests for testosterone and estrogen, so it should be avoided before those tests. The remaining five are neutral and only mention it, for example saying it helps clear oxalates, is low in some people, or is listed with a clear dose on some labels. Nobody gave a dose or a preferred form of biotin, and nobody said they stopped taking it. Vitamin D is a smaller ingredient in this product and drew the most support of the others, mostly from panelists who recommend getting enough of it.
See all 10 biohackers →Hide the biohackers
Dr. Eric Berg · Biotin · neutral
- States that thinning hair often indicates low biotin, which is required to produce keratin for hair, skin, and nails.
- Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
- Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
- Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
- Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
- Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
- Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
- Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
- Recommends increasing vitamin D to restore balance and support healthy blood pressure.
- States that a lack of vitamin D can potentially cause achy bones or crashing mood.
- Recommends taking zinc carnosine for an ulcer or some type of gastric problem.
- States that vitamin D is intimately involved in the immune system and recommends taking at least 10,000 IUs each day.
- Emphasizes the importance of zinc for decreasing viral replication and recommends taking 40 to 60 mg every single day.
- States that taking high doses of vitamin D3 for 14 days can improve mood, sleep, low back pain, skin issues, and blood pressure, as well as act as a natural anti-inflammatory and reduce susceptibility to sickness.
Thomas DeLauer · Biotin · warns
- Thinks biotin is a little overhyped, suggesting that consuming adequate protein is probably more effective for hair, skin, and nails. He notes that some people might be deficient, especially if consuming a lot of eggs with avidin, but doesn't consider it the 'Mecca of perfect hair'.
- Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
- Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
- Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
- Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
- Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
- Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
- Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
- Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
- Mentions that more zinc could be beneficial for testosterone, but it's not working on the axis that most people need help with.
- Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
- Compares zinc content, noting salmon has under 1mg while oysters have 74mg per 100g, a 70x difference.
- Compares iron content in spinach (2.7mg) and beef (2.6mg), but emphasizes that beef's heme iron absorbs at about 25%, while spinach's non-heme iron absorbs at 2-8%.
- Recommends getting vitamin D, suggesting it can be obtained while walking.
Dave Asprey · Biotin · neutral
- States that biotin clears out oxalates.
- Takes Vitamin DAKE from Suppgrade Labs.
- Suggests that vitamin D supports brain health, muscle function, and focus.
- States that folate can affect how the body responds to a supplement.
- Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
- States that currently, he is only taking vitamin C and vitamin D.
- Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
- Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
- Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
- States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
- Emphasizes the importance of having enough zinc before trying advanced longevity strategies like peptides.
- Suggests that zinc has better safety and protective data than meds for reducing cardio respiratory risk.
- Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
- Recommends Vitamin D as one of the most important supplements for overall health.
Andrew Huberman · Biotin · neutral
- Mentions biotin.
- Zinc carnosine to support and improve the lining of your gut.
- Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
- States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
- Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
- States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
- States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
- Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
- Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
- AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
- States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
- Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
Siim Land · Biotin · neutral
- Siim Land's company has published papers and filed patents for improvement in mitochondria in the skin using their core mitochondrial approach and other things like biotin.
- Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
- Recommends taking Vitamin D with fat for better absorption.
- States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
- Mentions that iron is a mineral necessary for making collagen.
- Thinks vitamin D has some of the strongest evidence and is worth considering.
- Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
- States that excess iron promotes oxidative stress and inflammation, which increases heart disease risk.
- Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
- Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
- Recommends taking Vitamin D in the morning or at lunch with fat.
- Notes that Boron improves vitamin D.
- Recommends Vitamin D because microglia contain Vitamin D receptors, and Vitamin D helps keep the immune system properly regulated, with low levels associated with greater neuroinflammation and a higher risk of autoimmune conditions.
- States that deficiencies in nutrients such as zinc can impair normal immune regulation.
Dr. Rhonda Patrick · Biotin · warns
- Advises avoiding biotin-containing supplements before a testosterone blood test as they can cross-detect with estrogens and confound results.
- Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
- Mentions that vitamin D also plays a role in maintaining muscle mass.
- Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
- Recommends ensuring adequate vitamin D intake for men's sperm health.
- Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
- Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
- Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Discusses findings from a meta-analysis on zinc supplementation, noting it improved insulin resistance, inflammation, and oxidative stress in people with diabetes or prediabetes, and explains its biological role in the pancreas.
- Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
- Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
- Recommends Vitamin D, explaining that it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity.
Peter Attia · Biotin · warns
- Warns that biotin, found in many supplements, can completely obscure findings and render a non-LCMS test for estradiol and testosterone irrelevant due to interference with ELISA-based assays.
- Lists vitamin D as one of her staple supplements.
- Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
- Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
- States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
- Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
- In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
- Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
- Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
- Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
- Peter Attia's AVIA Skincare vitamin C serum also contains niacinamide, which is useful to apply to the skin right after washing.
- Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
- Recommends iron supplements for women of reproductive age who are iron deficient.
- Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
Ben Greenfield · Biotin · recommends
- Recommends biotin (Vitamin B7) for supporting keratin production and strengthening hair, noting it can be found in eggs, almonds, and salmon.
- Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
- Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
- Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
- Mentions vitamin D as part of a bare-minimum protocol.
- Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
- Recommends methylfolate as an active form of folate that the body can use directly without conversion.
- Emphasizes that zinc sufficiency is crucial for immunity because the thymus-derived peptide thymulin, which trains lymphocytes, requires zinc to be active.
- Recommends adding zinc into one's stack because it is a co-factor for enzymes involved in testosterone synthesis and sperm maturation, and zinc deficiency is a reproducible cause of low sperm count.
- He mentions zinc as a supplement with real human data behind it for male fertility.
- Zinc may support both testosterone and sperm count.
- States that Nrf2 activators, when combined with something like niacin, may have a good effect on plaque progression.
- Has been taking Vitamin D3 K2 for over a decade.
- Warns that he was taking so much zinc without realizing it because it was in five different things he was taking, and he couldn't pinpoint the problem.
Dr. Mark Hyman · Biotin · recommends
- Recommends supplementing with biotin for hair follicle health and growth.
- Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
- Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
- Notes that vitamin D plays a role in immune function.
- Notes that some people may need a little bit extra folate with a supplement.
- Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
- Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
- States that vitamin D supplementation can help with oxidative stress.
- Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
- Mentions vitamin D as a key nutrient for supporting immune function.
- States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
- Recommends ensuring adequate zinc intake on a regular basis for immune support, noting some data on zinc lozenges for early cold.
Bryan Johnson · Biotin · neutral
- Mentions biotin as an example of an ingredient that AG1 lists with a specific dose, but then contrasts it with other ingredients in proprietary blends where doses are not disclosed.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
- Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
- Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
- Takes 5000 IU of Vitamin D3 in the morning for longevity.
- Takes 15 mg of Zinc in the morning for longevity.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Takes 15 mg of Zinc in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning.
RAL Summary
Members OnlyTier 2 for Hair Growth
A randomized trial found that biotin, at a lower dose than this product's 2500 mcg, reduced hair fall and sped growth [1], and 87% of 111 reviews are positive. The rules cited niacin, but those studies used niacin on the scalp, not by mouth, so the biotin trial is what supports this tier.
Where the evidence disagrees: 51 of the 94 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Skin, hair and nails, Endocrine system, Blood
Combine with: For hair support, pair it with collagen peptides, vitamin C (needed for collagen synthesis), iron if ferritin is low (confirm with a blood test), zinc, and omega-3 fatty acids for scalp health. If mood support is also a goal, add a separate mood-focused product, such as omega-3 EPA/DHA, vitamin D (if deficient), magnesium glycinate, saffron extract, or a B-complex with methylfolate. Talk to a healthcare provider before combining these with meds or other medications, especially 5-HTP, St. John's wort or SAMe, which can interact.
Possible side effects: The biotin trial reported no side effects. The company advises women with a history of breast cancer to ask their oncologist before use, because the product contains chasteberry. It also contains egg.
Supplement Facts
Vitamin D3 15 mcg · Vitamin E 0.77 mg · Niacin 15 mg
| Vitamin D3 | 15 mcg | |
| Vitamin E | 0.77 mg | |
| Niacin | 15 mg | |
| Vitamin B6 | 1.7 mg | |
| Folate | 400 mcg DFE | |
| Vitamin B12 | 10 mcg | |
| Biotin | 2,500 mcg | |
| Iron | 8 mg | |
| Zinc | 10 mg | |
| BioActive Growth MultiSystem | 0 | † |
| FollicleFlow BioComplex | 0 | † |
Other ingredients: Vegetable Capsule (Hypromellose).
Directions: Take 2 Capsules Daily With Water
Label source: Reverseagelab · Report a label change
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Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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