SuperSmart Polypodium Leucotomos Extract 1000 mg Review
SuperSmart offers a Polypodium Leucotomos Extract supplement, also known as PLE, which the page describes as a type of fern extract found in the American tropics and sub-tropics. The product is presented as a natural supplement extracted from the leaves and standardized to 1000 mg per day with a 4:1 ratio, which the listing states is equivalent to 4000 mg per day. The page's feature list identifies the product as non-GMO, gluten free, and vegetarian friendly. It states that the brand offers quality supplements for women and men, though it describes the product as difficult to find elsewhere. Directions on the page say to take 2 capsules a day. The listing states that each vegetarian capsule contains 500 mg of Polypodium leucotomos 4:1 leaf extract. The other ingredients are listed as acacia gum and white rice flour. The bottle is listed as containing 90 vegetarian capsules, and the comparison table on the page classifies the form as capsules, with unflavored flavour and polypodium leucotomos as the primary ingredient. The brand states it has been operating since 1992 and says it wants customers to be fully satisfied, inviting questions by phone or message at any hour, described as 24/7. The seller is listed as SuperSmart, a Pro Seller, and the product is fulfilled by Walmart with free 90-day returns. The current price shown is 20.00 dollars, with a one-time purchase option and a subscription option at the same price. Delivery is shown as arriving tomorrow to the Sacramento area, while pickup availability is listed as check nearby. The page includes product detail, indications, directions, warranty, and ingredients sections, though the scraped text shows only headers for those sections without their full content. The product's average rating is shown as 4.7 out of 5 from 19 ratings, with 12 written reviews. Customers reviewing this supplement describe daily morning use, sun-related expectations, and value. The listing makes no independent clinical claims beyond its own feature text. Buyers comparing this product should check the label and the stated 4:1 extract ratio against their own needs and should consult a health professional before use.
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Study, Trial or Testing Result Summary
Members Only5 human studies · 4 improved
This product gives 1000 milligrams a day of Polypodium leucotomos fern extract, above the 480 milligrams used in the main skin trial. In 40 healthy adults, 480 milligrams a day for 12 weeks was followed by better skin hydration and elasticity and less water loss through the skin, both with the extract alone and with a fern and pomegranate mix, with no difference between them; there was no placebo group, so the effect cannot be clearly credited to the extract [1]. In 40 people with dark facial patches already using a lightening cream and sunscreen, the oral extract sped up improvement at 8 and 12 weeks compared with placebo, but both groups ended up similar [2]. A small study of 20 women with no comparison group found a sunscreen containing the extract reduced dark patches by about 44 percent, but it did not measure wrinkles, elasticity or hydration [3]. In 10 adults, the oral extract reduced sun-related burning [4]. A review of 21 studies found sun-protective and calming effects with a good safety record, but it did not report wrinkle, elasticity or hydration results [5]. No study measured wrinkles directly. Animal and cell studies are never counted.
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- A review of 21 studies, including 11 randomized trials, found oral fern extract had sun-protective and immune-calming effects across several skin conditions, with a good safety profile, but it did not report wrinkle, elasticity or hydration results.The Utility of Oral Polypodium Leucotomos Extract for Dermatologic Diseases: A Systematic Review.
- In 40 healthy adults given 480 mg a day for 3 months, skin hydration and elasticity improved and water loss through the skin fell with both the fern extract alone and the fern-pomegranate mix, with no difference between them.Comparative effects of a fixed Polypodium leucotomos/Pomegranate combination versus Polypodium leucotomos alone on skin …
- In 40 people with melasma using hydroquinone cream and sunscreen, 12 weeks of oral fern extract lowered melasma scores faster than placebo at 8 and 12 weeks, but both groups improved similarly by the end and skin pigment and redness did not differ.Double-blind, Placebo-controlled Trial to Evaluate the Effectiveness of Polypodium Leucotomos Extract in the Treatment o…
- In a 12-week uncontrolled pilot of 20 women, a daily sunscreen containing Polypodium leucotomos extract reduced melasma severity by about 44% from baseline, with the improvement holding at 24 weeks; the study had no control group and did not measure wrinkles, elasticity, or hydration.A 50+ Sunscreen Containing Polypodium Leucotomos Extract, Ellagic Acid, and Niacinamide in Facial Melasma and Photoaging…
- In 10 healthy adults, oral fern extract at 7.5 mg per kg reduced skin burning and later pigmentation from a light-sensitizing UVA treatment and protected skin cells, but it did not test wrinkles, elasticity or hydration.Orally administered Polypodium leucotomos extract decreases psoralen-UVA-induced phototoxicity, pigmentation, and damage…
Review Totals and Summary
Members Only366 reviews · 88% positive
**Overall:** Buyers are very positive about the SuperSmart Polypodium Leucotomos Extract 1000 mg capsules, which carry about 306 ratings across the stores. Most of the praise is about sun-related skin protection, though many reviews are short and light on detail. **What buyers say it did for them:** The most common theme is help with sun exposure. One buyer says it "really prevents sunburn," describing being out all day in flip flops with no sunscreen: "My feet turned red, but they did not burn." A long-term user whose dermatologist recommended it reports only one possible cancer spot in the last 3 years, after 29 lesions in 10 years. Another reports "it has helped my skin from vitiligo." One buyer takes it for blue light from monitors, and one says it works fast on pain, which is unusual and not explained. Others just say "I love it. It works." **What they complain about:** There are no complaints in the reviews or store summaries. Nobody mentions taste, size, shipping or side effects. The lack of complaints is partly because many reviews are brief. One reviewer is candid that there is "no way I can discern" whether it protects the skin from UV, even though they take it every morning before gardening. The Walmart page histogram shows one one-star and one four-star rating among mostly fives, but no text explains them. **Taste, smell, pill size or form:** Nothing is said about these. The store summaries confirm that the pages carry no comments on capsule size, swallowing, taste, or number of capsules per bottle. Only the capsules are covered here, and any reviews of other forms were left out. **Value for money:** Two buyers raise price. One says "The price and quality is great." The dermatologist-recommended user found the brand much cheaper than the recommended one, with "no unhealthy ingredients." That is the clearest value point in the feedback. **Who it seems to suit and who it did not:** It seems to suit people who spend time in the sun, such as gardeners and those outdoors all day, and people whose dermatologist suggested a Polypodium supplement. Some also take it for screen time or skin conditions, though those claims come from single reviewers. Even enthusiastic buyers keep up other protection: one still wears sunscreen, and another uses a parasol or natural sunscreen when UV is 3 or higher. No one reports that it did not suit them, but the SuperSmart page notes it offers little detail on dosage tolerance, long-term use or comparisons with other products. The overall tone is positive but thin on specifics.
Biohacker Summary
Members Only3 of 10 recommend it
Only one of the ten panelists spoke about Polypodium leucotomos, the main ingredient in this product, so there is very little to go on. That person recommends it and describes it as a fern from South America with strong antioxidant properties. They take it to support skin from within and help skin resist damage from free radicals. They mention it as one ingredient in a summer skin supplement, but give no dose, preferred form, or caution, and no one on the panel said they stopped using it.
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Ben Greenfield · Polypodium leucotomos · recommends
- Recommends polypodium leukotamos, a fern from South America, as an ingredient in the Summer Ready supplement that has powerful antioxidant properties to support skin from within and strengthen its ability to resist free radical damage.
RAL Summary
Members OnlyTier 3 for Younger-Looking Skin for Women
Only one study measured skin hydration or elasticity, and it compared the fern extract with a fern and pomegranate mix and had no placebo group, so it does not clearly show improvement for this goal; the other studies counted as improvements looked at dark patches or sunburn. So it is graded Tier 3, lower than the rules alone gave.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Skin, Immune system
Combine with: To strengthen skin photoprotection and anti-photoaging, pair Polypodium leucotomos with oral antioxidants such as astaxanthin (4-12 mg), lycopene, or lutein/zeaxanthin, and with vitamin C and vitamin E, which work synergistically against UV oxidative stress. Collagen peptides (2.5-10 g) with vitamin C support skin structure and elasticity, while hyaluronic acid supports hydration. Nicotinamide (vitamin B3, 500 mg once or twice daily) has good evidence for supporting skin DNA repair after UV exposure and is the most relevant addition for the cellular repair goal. If broader cellular and DNA support is wanted, consider NAD+ precursors (NMN or NR), resveratrol or pterostilbene, and omega-3 fatty acids. Topical broad-spectrum sunscreen should remain the foundation of UV protection, and a clinician should be consulted for anyone with a history of skin cancer, on immunosuppressants, or who is pregnant.
Possible side effects: Studies report a good safety profile, and no side effects are mentioned in the reviews.
Supplement Facts
Polypodium leucotomos Leaf Extract 1000 mg
| Polypodium leucotomos Leaf Extract | 1,000 mg | † |
Other ingredients: Acacia Gum, White Rice Flour.
Directions: Directions: Adults. Take one to two capsules daily in the morning 30 minutes prior sun exposure.
Barcode (UPC) 05453003825494 · Label source: NIH label database · Report a label change
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More younger-looking skin for women products
Members OnlyThe highest ranked for the same goal
Graded November 7, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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