Tailwind Nutrition Endurance Fuel Review

Endurance Fuel from Tailwind Nutrition is a carbohydrate and electrolyte drink mix built for longer endurance activities. The product page describes it as a fuel that provides carbohydrates for energy along with sodium, potassium, magnesium, and calcium. You mix it with water and drink it throughout your effort. The page says it is made to be simple to use: just pour, shake, and go. The flavors are described as light and refreshing, meant to stay easy to drink mile after mile whether you are running, riding, or out on the trail. It can be used with a bottle, a hydration pack, or a soft flask. Tailwind presents the drink as smooth, stomach-friendly fuel that goes the distance with you. The page highlights three ingredient groups under the heading 3 Ingredients For Going The Distance. The first is electrolytes. Tailwind says the formula contains sodium, potassium, magnesium and calcium to speed the absorption of fuel and replace what you sweat out. The second is water. The page states that Endurance Fuel maximizes your absorption of water, more than if you were to drink water alone. The third is calories. The formula uses dextrose and sucrose, which the page says matches what the body is designed to absorb, so it enters the bloodstream quickly without challenging the digestive system or causing stomach issues. The nutrition facts shown on the page list a serving size of 27g, with 100 calories, 0g total fat, 0mg cholesterol, 310mg sodium (13% DV), 25g total carbohydrates (9% DV), 0g dietary fiber, 25g total sugars including 25g added sugars (50% DV), 0g protein, 27mg calcium (2% DV), 90mg potassium (2% DV), and 12mg magnesium (2% DV). The page notes that the drink is non-GMO, gluten free, vegan, and free of dairy and soy. Organic caffeine is included only in the caffeinated flavors, which the page marks with an asterisk. The flavor list includes Dauwaltermelon, Mandarin, Lemon, Berry, Naked (Unflavored), Grape, Raspberry (Caffeinated), and Tropical (Caffeinated). Sizes offered include 50 servings, single serving, single serving 12 pack, and 30 servings. The page directs buyers to mix it with 20 to 24 ounces (590 to 710 ml) of water. Its feature points are light clean taste, mixing clear and rinsing clean, being easy on the gut, and having no fake stuff. At the time of capture the product shows as out of stock, priced at $42.99 USD, with a note that a customer can earn rewards points on the purchase.

Product Focus: EnergyAlso covers:MusclesMetabolismHeart
Tier ⓘ
Tier 3 · Rank 5
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 5 within Tier 3 for Energy; 28 of 86 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
76 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
96% of 10,802
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only121 human studies · 63 improved

22 of these 121 human studies gave the ingredient by drip or injection, not by mouth.

121 human studies63 improved44 no effect161,694 people studied

The studies we have cover only the small mineral and vitamin amounts on this drink mix's label, not its main sugars, salt or caffeine, so they say little about how it fuels exercise. None of the studied ingredients is at a full dose. Magnesium is 12 milligrams, below the 80 milligrams that eased tiredness in adults with metabolic conditions [1]. Other magnesium trials found no change in fatigue [2]. Calcium is a trace 27 milligrams, far below the 1000 milligrams a day that eased early tiredness in women with premenstrual syndrome [3]. Calcium loading did not help runners' aerobic capacity [4]. Potassium, at 90 milligrams, has mixed and limited evidence. A drink containing potassium, taken in a set amount during recovery, helped trained runners run longer later [5], but a glucose drink did not delay fatigue in another small trial [6]. Vitamin D and iron amounts are not shown on the label. Vitamin D eased tiredness in people low in it [7] but not in a large trial of older women [8]. Iron eased tiredness in people low in iron [9]. Animal and cell studies are never counted.

See all 121 studies →Hide the studies

Review Totals and Summary

Members Only10,802 reviews · 96% positive
10,802 reviews · Tailwind Nutrition 4,116 · Amazon 1,875 · Google 695
96% positive2% neutral2% negative

Buyers are very positive about Tailwind Endurance Fuel powder, which carries about 10,107 ratings across the stores. Reviewers mostly praise it for steady energy on long efforts, a light taste and easy mixing, with only small complaints about packaging and cost. **What it did for them:** Buyers describe a noticeable lift and reliable fuelling on long sessions. One mountain biker says "You can actually feel it working!" and went from almost bonking to feeling strong. Another says "I use this on every long run and it's never let me down." A long-time user says they have used it for over 13 years and "would not be able to train and compete without it." The store summaries add that people report sustained energy over multi-hour runs, rides and hikes without stomach trouble, and that it helps them avoid cramping and bonking. Most reviewers describe consistent performance across different sports and conditions. **What they complain about:** Complaints are few. The store summaries mention that a small number of reviewers raise concerns about packaging durability and the cost per use. They say the negatives concern packaging and price rather than taste or stomach comfort. None of the written reviews here include a complaint. **Taste and mixing:** Reviewers like the lighter flavor. One who wanted something "lighter, less sweet" than Skratch says "I've really been liking the taste of Tailwind." The same reviewer felt thirstier after drinking Skratch but not with Tailwind Endurance. The store summaries say it mixes easily and tastes light and refreshing, with flavors that are not overly sweet. Watermelon-lime and raspberry are named as favorites. Nothing is said about pill size, since this is a powder. **Value for money:** Cost comes up only as a minor concern. The store summaries say a few reviewers mention the cost per use. No written review gives a price comparison or says it is poor value, so there is little more to say on this point. **Who it suits:** It seems to suit endurance athletes: mountain bikers, trail runners and long-distance runners, including people who train many hours a week and use it for efforts of 4 to 8 hours. It also suits people who want calories in a drink that is less sweet, "more like Nuun, but with calories," as one reviewer puts it. The store summaries add that people value the company's service, with one reviewer praising fast shipping and another mentioning a handwritten thank-you note. As one puts it, "Awesome company, super fast shipping, and amazing products." Nobody in the reviews says it did not suit them. The store pages state that 98% of reviewers would recommend it. **Other forms:** Reviews of other forms of the product, such as gummies or capsules, were left out. This summary covers the powder only.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Vitamin D is the main ingredient here, and all ten panelists spoke about it, with most recommending it or taking it themselves. They take it for general health, immune support, muscle, brain health and longevity, and several use it mainly in fall and winter when sun is low. Doses they gave range from 5,000 units daily, taken in the morning by two of them, to at least 10,000 units in winter from one, and several suggest testing blood levels first, with targets from 40 to 100. One advises taking it with dietary fat for better absorption, and one cautions that it may not be worth taking unless you are deficient. Magnesium is a smaller ingredient in this product, and many of the panel use it, mostly for sleep.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Vitamin D · warns
    • 2 Nov 2026 · warns · Facebook ↗
      Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
    • 30 Oct 2026 · recommends · YouTube ↗
      Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
    • 30 Oct 2026 · recommends · YouTube ↗
      Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
    • 30 Oct 2026 · Iron · neutral · YouTube ↗
      Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
    • 30 Oct 2026 · Magnesium · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 29 Oct 2026 · Potassium · recommends · Podcast ↗
      States that people need more potassium than any other mineral, yet most people aren’t getting enough.
    • 28 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 28 Oct 2026 · Potassium · recommends · YouTube ↗
      Explains that potassium is essential for peristalsis, the pumping action through the colon, and without it, things can sit there, leading to constipation.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
    • 25 Oct 2026 · recommends · X ↗
      Recommends increasing vitamin D to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · Magnesium · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Potassium · neutral · YouTube ↗
      Explains that the normal requirements for potassium are 4,700 mg every single day, and that very few people get half of that amount. They describe potassium's role in the sodium potassium pump, which is essential for cellular electricity, muscle contraction, and heart function. Deficiency can lead to tiredness, muscle cramps, heart palpitations, or rising blood pressure.
  • Dave Asprey · Vitamin D · uses
    • 1 Nov 2026 · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 31 Oct 2026 · Magnesium · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 25 Oct 2026 · Magnesium · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 9 Oct 2026 · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 27 Sep 2026 · Magnesium · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · Magnesium · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
    • 5 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
    • 3 Sep 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
  • Siim Land · Vitamin D · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 25 Oct 2026 · Magnesium · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 24 Oct 2026 · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 14 Oct 2026 · Iron · neutral · Instagram ↗
      Mentions that iron is a mineral necessary for making collagen.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 7 Oct 2026 · Magnesium · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · Magnesium · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · Magnesium · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · Magnesium · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 30 Sep 2026 · Potassium · neutral · X ↗
      Lists potatoes and fruit as sources of Potassium.
    • 30 Sep 2026 · Calcium · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks vitamin D has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · neutral · X ↗
      Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
  • Ben Greenfield · Vitamin D · recommends
    • 29 Oct 2026 · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 29 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 22 Oct 2026 · Magnesium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 22 Oct 2026 · Potassium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Magnesium · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · Magnesium · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 3 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · Magnesium · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 20 Aug 2026 · uses · YouTube ↗
      Has been taking Vitamin D3 K2 for over a decade.
    • 17 Aug 2026 · Magnesium · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 17 Aug 2026 · Potassium · recommends · Instagram ↗
      Recommends Celtic Sea Salt's new electrolyte drink 'Hydrate' for replenishing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, magnesium, taurine, and potassium, with no added sugar, artificial colors, or synthetic ingredients.
    • 15 Aug 2026 · Magnesium · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
  • Dr. Mark Hyman · Vitamin D · recommends
    • 26 Oct 2026 · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 1 Nov 2026 · Magnesium · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 21 Oct 2026 · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Iron · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 16 Oct 2026 · Potassium · warns · Facebook ↗
      Warns that potassium bromate, a dough conditioner banned in the EU, UK, and Canada, is still allowed in U.S. bread.
    • 14 Oct 2026 · Magnesium · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 8 Oct 2026 · recommends · Instagram ↗
      Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
    • 7 Oct 2026 · neutral · Podcast ↗
      Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
    • 7 Oct 2026 · recommends · YouTube ↗
      States that vitamin D supplementation can help with oxidative stress.
    • 7 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 5 Oct 2026 · neutral · Podcast ↗
      Mentions vitamin D as a key nutrient for supporting immune function.
  • Thomas DeLauer · Vitamin D · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 28 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 28 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's cans which contain 100 milligram potassium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 24 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's 100 mg potassium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 20 Oct 2026 · recommends · YouTube ↗
      Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
    • 8 Oct 2026 · Magnesium · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · uses · YouTube ↗
      Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
    • 6 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 5 Oct 2026 · recommends · YouTube ↗
      Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
    • 1 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 29 Sep 2026 · uses · YouTube ↗
      Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
  • Bryan Johnson · Vitamin D · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 22 Oct 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Jul 2026 · Iron · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · Iron · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 3 Jul 2026 · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 4 May 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 2 May 2026 · Magnesium · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 21 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
  • Dr. Rhonda Patrick · Vitamin D · neutral
    • 5 Oct 2026 · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 29 Oct 2026 · Magnesium · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · Magnesium · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 30 Sep 2026 · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 29 Sep 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 28 Sep 2026 · Magnesium · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 24 Sep 2026 · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
    • 2 Sep 2026 · Magnesium · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 25 Aug 2026 · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 10 Aug 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
    • 10 Aug 2026 · Magnesium · recommends · X ↗
      Recommends considering magnesium to improve mood.
    • 28 Jul 2026 · recommends · Facebook ↗
      Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
    • 28 Jul 2026 · Magnesium · recommends · Facebook ↗
      Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
  • Andrew Huberman · Vitamin D · neutral
    • 21 Sep 2026 · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 22 Oct 2026 · Magnesium · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 7 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · Magnesium · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 27 Jul 2026 · Potassium · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 20 Jul 2026 · recommends · YouTube ↗
      States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 20 Jul 2026 · Iron · recommends · YouTube ↗
      States that Iron is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 20 Jul 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · Magnesium · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 13 Jul 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning.
    • 13 Jul 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 5,000 IU of Vitamin D3 in the morning for overall health.
  • Peter Attia · Vitamin D · uses
    • 4 Jan 2026 · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 6 Sep 2026 · Potassium · recommends · YouTube ↗
      States there is some evidence that increasing dietary potassium through potassium-rich foods like bananas and potatoes, rather than supplements, can lower blood pressure.
    • 1 Jun 2026 · Magnesium · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · Magnesium · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 16 Nov 2025 · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 15 Sep 2025 · Magnesium · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 6 Aug 2025 · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 3 Aug 2025 · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 10 Jul 2025 · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
    • 9 Jul 2025 · Magnesium · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 9 Jul 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 6 Jul 2025 · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.

RAL Summary

Members OnlyTier 3 for Energy

Tier 3 rests on strong reviews, with 96% of 10802 reviews positive. Study support is thin, because the evidence covers only trace minerals at doses below those that worked in studies [1][3].

  • Vitamin D: amount hidden in a blend
  • Calcium: trace amount
  • Iron: amount hidden in a blend
  • Magnesium: below the dose that worked in studies

Where the evidence disagrees: 44 of the 121 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Muscular system, Metabolic system, Cardiovascular system

Combine with: If you use this product for endurance training, pair it with a separate cellular-health stack for the anti-aging goal. Options include NAD+ precursors such as nicotinamide riboside or NMN to support cellular energy metabolism and sirtuin activity; trans-resveratrol or pterostilbene with a fat source for better absorption; CoQ10 (ubiquinol) and PQQ for mitochondrial support; alpha-lipoic acid and N-acetylcysteine or glutathione to bolster antioxidant defenses; omega-3 fatty acids (EPA/DHA) to reduce inflammation; and vitamin D3/K2, magnesium, and folate/B12 (methylated) for DNA methylation and repair pathways. Spermidine, fisetin, and quercetin are also studied for autophagy and senescence support. For endurance sessions, adding magnesium, potassium, and a small amount of protein or amino acids can improve recovery. Consult a healthcare provider before starting new supplements, especially if you have blood pressure or blood sugar concerns, since this product contains sodium and fast-acting carbohydrates.

Possible side effects: No major side effects reported. One large diet trial linked a low-salt, high-potassium diet to more fatigue, but that is far beyond this product's amount.

Supplement Facts

Vitamin D 0 mcg · Calcium 27 mg · Potassium 90 mg
Supplement Facts
Serving Size 1 scoop (27g)
Servings Per Container 50
Amount Per Serving% Daily Value
Total Fat0 g
Saturated Fat0 g
Trans Fat0 g
Cholesterol0 mg
Sodium310 mg
Total Carbohydrate25 g
Dietary Fiber0 g
Total Sugars25 g
Added Sugars25 g
Protein0 g
Vitamin D0 mcg
Calcium27 mg
Potassium90 mg
Iron0 mg
Magnesium12 mg

Other ingredients: Dextrose (Glucose)*, Cane Sugar*, Citric Acid, Sodium Citrate, Sea Salt, Potassium Chloride, Organic Mandarin Orange Flavor, Calcium Carbonate, Magnesium Oxide. *Non-GMO.

Directions: Mix 2–3 scoops with 20–24oz (590–710ml) water per hour for longer efforts, or 1–2 scoops per hour for shorter ones. Adjust to taste and energy needs. Sip often and enjoy the journey.

Barcode (UPC) 850039211386 · Label source: Reverseagelab · Report a label change

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Our articles on this subject

Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.