Thorne Heart Health Complex Review

Thorne's Heart Health Complex is a capsule supplement that combines coenzyme Q10 (CoQ10), hawthorn (Crataegus oxycantha), potassium, taurine, and magnesium. The product is described as a combination of coenzyme Q10, minerals, amino acids, and botanicals intended to benefit the heart, providing the heart muscle and blood vessels with nutrients for healthy functioning. The product is sold as 90 capsules, with a serving size of 3 capsules and 30 servings per container. The cells that make up the heart muscle have a very high metabolism and need CoQ10 as an energy-producing cofactor. The page states that numerous studies on CoQ10 have shown its benefit in cardiovascular function, and that CoQ10 also serves as an antioxidant. Thorne's formula combines CoQ10 with taurine, an amino acid that research indicates can support already normal levels of cholesterol. Taurine aids in the regulation of intracellular calcium levels, which helps protect the heart muscle and support cardiac rhythm. The flavonoid compounds in hawthorn appear to strengthen blood vessels and support cardiac function. Hawthorn has also been shown to help maintain already normal blood pressure, heart rate, and exercise capacity. The minerals magnesium and potassium are described as necessary for optimal cardiovascular function. The page notes that in a 73-subject study supplementing CoQ10 at 120 mg daily, improvements in cardiovascular function were observed after 28 days. The flavonoids in hawthorn also act as antioxidants and support artery function. Taurine is described as an essential nutrient cofactor for cardiac function and rhythm, and as the most abundant amino acid in the heart. Its support for already normal cholesterol levels is probably due to its ability to facilitate the conversion of cholesterol to bile acids. Thorne states that Heart Health Complex is formulated with the scientific rigor the brand is known for, with each ingredient carefully selected, clinically studied, and tested through multiple rounds of quality control for purity, potency, and consistency. The product is described as trusted by health-care practitioners. The page says the product has been third-party tested and certified to verify that what is in the package matches the label and contains no unsafe levels of contaminants such as heavy metals, pesticides, and microorganisms. The warnings section states the product is contraindicated in individuals with a history of hypersensitivity to any of its ingredients. Pregnant people are advised to consult a health-care practitioner before use. The page reports no known adverse interactions or contraindications at publication date. It also notes that gas, bloating, or diarrhea may occur in some individuals taking magnesium supplements, which can happen at varying amounts and resolves when the amount is reduced. The subscription option offers 10% off, with additional discounts for subscribing to multiple products, and the product is listed as HSA/FSA eligible.

Product Focus: Blood PressureAlso covers:Heart
Tier ⓘ
Tier 2 · Rank 5
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 5 within Tier 2 for Blood Pressure; 5 of 37 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
87 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
93% of 1,165
Biohacker Mentions
10 of 10
Cost per month
$14

Study, Trial or Testing Result Summary

Members Only213 human studies · 111 improved

13 of these 213 human studies gave the ingredient by drip or inhaler, not by mouth.

213 human studies111 improved68 no effect159,985 people studied

Three of the main ingredients come at or near the doses that worked in studies. Taurine, at 1800 mg a day, lowered the top blood pressure number by about 4 points and the bottom number by about 1.5 to 2.5 points in several pooled analyses of randomized trials [1][2][3]. In people with borderline high blood pressure, 1.6 grams a day for 12 weeks lowered the top number more than placebo [4]. Magnesium, at 400 mg a day, modestly lowered blood pressure by about 2 to 3 points in large pooled analyses [5][6]. The benefit showed up mainly in people with uncontrolled high blood pressure, not in people with normal pressure [7]. This dose is above the daily recommended limit, so members can take less. Coenzyme Q10, at 90 mg a day, lowered the top number by about 4.8 points across 26 trials [8], although studies in people with diabetes found no change [9]. Hawthorn, at 700 mg a day, gave mixed results: it lowered blood pressure in some trials [10] but not in others [11]. Potassium is present at only 190 mg, far below the studied dose of 30 millimoles a day. Most of its evidence comes from potassium-enriched salt [12]. Animal and cell studies are never counted.

See all 213 studies →Hide the studies

Review Totals and Summary

Members Only1,165 reviews · 93% positive
1,165 reviews · IHerb 729 · Amazon 307 · Vitacost 69 · Thorne 33 · Walmart 26 · NHC 1
93% positive1% neutral6% negative

Thorne Heart Health Complex has about 1,165 ratings across the stores that sell it, and most buyers are happy with it. They praise the quality and the brand, and several report real changes, though a few complain about price, the subscription and the taste. This summary covers the capsules only. Reviews of other forms were left out. **What buyers say it did for them:** Some describe clear benefits. One wrote, "I have had difficulties with a racing heart, and leg cramps," and recommends it after four months. Another reported being in afib for 24 hours or more once or twice a week, then "ZERO Afib" after six weeks. Others mention more energy ("I definitely feel my energy levels up") and a smaller waistline, though that buyer was also eating well and exercising. A Vitacost reviewer says palpitations stopped. Another buyer says only "I feel like it's helping." These are individual experiences. **What they complain about:** One buyer who is 78 noticed no difference after 30 days. They concluded that ubiquinol, not the ubiquinone form of CoQ10 used here, would suit their age better. Another found the capsule taste poor. One complained of "Too much packaging". A long-time customer called the subscription program "terrible and hard to modify" but still trusts the products. Another buyer found they were doubling up because their multivitamin already covered the same ground. **Taste, smell, pill size and form:** The one comment on size is positive: "Capsules aren't huge." One reviewer found the taste of the capsule "not too great" and wondered whether a gummy version might exist. Beyond that, reviewers say little about taste, smell or swallowing. **Value for money:** Price is the main sore point, and it comes from a single reviewer. Their 500mg taurine capsules were discontinued in favor of this formula, which they call "3x as expensive" and full of ingredients they don't want. Others don't comment on price, though one likes that they "can use one product." A buyer on NHC.com liked that it combined ingredients they had been buying separately, which simplified their routine. Subscription handling is a separate cost concern raised by one reviewer. **Who it seems to suit and who it did not:** It seems to suit people who already trust Thorne and want several heart-related ingredients in one capsule, including hawthorn and CoQ10. Some long-term users say they have been satisfied for years. It suited less well: - people who only wanted a single ingredient like taurine - people who already take a multivitamin and find the overlap unnecessary - an older buyer who wanted the ubiquinol form of CoQ10 and saw no benefit in a month - people who dislike subscription programs Written feedback is thin on several pages, and some store pages show only a handful of reviews. The star ratings still lean strongly positive.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Magnesium is the main ingredient, and most of the panel recommends or uses it, with the rest staying neutral and one panelist noting it does not fix waking in the night. Sleep is the top reason, with several taking it before bed, and others cite muscle function, blood pressure, constipation relief, bone health and hydration during exercise or fasting. Forms named include glycinate and threonate, with 400 mg of threonate before bed the most common dose, while others mention 300 mg before bed, 300 to 500 mg a day as a minimum, and an electrolyte drink with sodium and potassium. Two panelists warn that labels can overstate the real magnesium dose, since the listed compound weight is not the same as the elemental amount. Potassium is a smaller ingredient in this product, and the panel mostly talks about it as an electrolyte or a mineral many people do not get enough of.

See all 10 biohackers →Hide the biohackers
  • Dr. Mark Hyman · Magnesium · uses
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 16 Oct 2026 · Potassium · warns · Facebook ↗
      Warns that potassium bromate, a dough conditioner banned in the EU, UK, and Canada, is still allowed in U.S. bread.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 16 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
    • 9 Sep 2026 · uses · YouTube ↗
      Has recommended Magnesium Breakthrough from Bio Optimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from Bio Optimizers, which contains 10 bioavailable forms of magnesium, as it plays a critical role in sleep recovery, stress regulation, and muscle function, and has become part of his evening routine, especially during periods of travel, training, and higher stress.
    • 20 Aug 2026 · Potassium · neutral · YouTube ↗
      States that potassium plays a critical role in nerve signaling and muscle contraction, especially in the heart, and low levels can lead to dangerous irregular heart rhythms.
    • 28 Jul 2026 · Potassium · neutral · Facebook ↗
      Notes that meds flush out potassium.
    • 17 Jun 2026 · Potassium · recommends · TikTok ↗
      States that with potassium, water can fully cross the cell membrane and get inside where it's needed for intracellular hydration.
  • Dave Asprey · Magnesium · neutral
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 25 Sep 2026 · Taurine · neutral · Podcast ↗
      Dave Asprey explains that a 2017 study in rats found taurine pretreatment reduced several behavioral and biochemical effects of chronic unpredictable stress, but notes this does not show that taurine treats depression in humans.
    • 18 Sep 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine, a common longevity molecule, affects the sense of smell, but they do not know why it works.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 1 Sep 2026 · Coenzyme Q10 · uses · YouTube ↗
      States he takes 300 mg of Coenzyme Q10 every day for 20 years because it is necessary for mitochondria to function and is important for longevity, noting that meds lower it.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
    • 29 Aug 2026 · Taurine · uses · YouTube ↗
      Dave Asprey takes taurine, acknowledging it's cheap and safe, but notes that while mouse studies show spectacular longevity benefits, human data is currently only observational and lacks randomized longevity trials.
    • 15 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends adding 300 or 400 mg of magnesium glycinate before bed to improve deep sleep quality, support growth hormone release, and burn visceral fat while asleep.
    • 28 Jul 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the extensively researched ingredients in Kill Switch that helps with natural sleep.
  • Dr. Eric Berg · Magnesium · neutral
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 29 Oct 2026 · Potassium · recommends · Podcast ↗
      States that people need more potassium than any other mineral, yet most people aren’t getting enough.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 28 Oct 2026 · Potassium · recommends · YouTube ↗
      Explains that potassium is essential for peristalsis, the pumping action through the colon, and without it, things can sit there, leading to constipation.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Potassium · neutral · YouTube ↗
      Explains that the normal requirements for potassium are 4,700 mg every single day, and that very few people get half of that amount. They describe potassium's role in the sodium potassium pump, which is essential for cellular electricity, muscle contraction, and heart function. Deficiency can lead to tiredness, muscle cramps, heart palpitations, or rising blood pressure.
    • 25 Oct 2026 · Potassium · recommends · X ↗
      Recommends increasing potassium to restore balance and support healthy blood pressure.
    • 24 Oct 2026 · recommends · Instagram ↗
      Dr. Eric Berg suggests that magnesium could help support deeper, more restful sleep.
    • 24 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Glycinate, noting that the combination of magnesium and glycine is helpful for connective tissue, sleep, and reducing stress.
    • 23 Oct 2026 · recommends · Instagram ↗
      Recommends taking magnesium 90 minutes to 2 hours before bedtime to support better sleep.
    • 23 Oct 2026 · recommends · YouTube ↗
      Suggests that magnesium glycinate can help support the missing 'break pads' on the nervous system, which contribute to constant pain.
    • 23 Oct 2026 · Potassium · recommends · YouTube ↗
      States that potassium is the most important electrolyte and that most people are not getting enough of it, needing around 4,700 mg daily, or even more, to avoid issues like fatigue, muscle cramps, heart palpitations, high blood pressure, and fluid retention.
    • 23 Oct 2026 · Potassium · neutral · Instagram ↗
      Dr. Eric Berg states that potassium is essential for health, supporting healthy muscles, nerves, and heart function, but warns that getting too much, especially from supplements, can be dangerous.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 22 Oct 2026 · Potassium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 16 Sep 2026 · Taurine · neutral · X ↗
      Taurine on its own isn’t particularly impressive as an ergogenic aid, but when combined with caffeine, there are significant increases in power production.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 17 Aug 2026 · Potassium · recommends · Instagram ↗
      Recommends Celtic Sea Salt's new electrolyte drink 'Hydrate' for replenishing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, magnesium, taurine, and potassium, with no added sugar, artificial colors, or synthetic ingredients.
    • 15 Aug 2026 · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 13 Jun 2026 · neutral · X ↗
      Notes a new study indicating that magnesium is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
    • 18 Apr 2026 · Taurine · recommends · YouTube ↗
      Recommends taurine supplementation, especially for plant-based dieters, citing a 2023 study showing its decline with age and its potential to extend health span and restore markers of brain aging in mice, with anecdotal evidence for human brain function.
  • Dr. Rhonda Patrick · Magnesium · neutral
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 12 Oct 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine depletion is a concern raised in long-term animal studies regarding Beta Alanine, though not observed in human trials, and notes that one can supplement with taurine, which is a beneficial compound.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 10 Aug 2026 · neutral · Facebook ↗
      States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
    • 10 Aug 2026 · recommends · X ↗
      Recommends considering magnesium to improve mood.
    • 28 Jul 2026 · recommends · Facebook ↗
      Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
    • 29 Jun 2026 · neutral · Facebook ↗
      Mentions that kale delivers magnesium, a micronutrient many diets fall short on.
    • 26 Jun 2026 · recommends · Facebook ↗
      Recommends Magnesium, stating it is a cofactor for over 300 biological processes, including DNA repair, energy production, and sleep regulation.
    • 23 Jun 2026 · Potassium · recommends · Facebook ↗
      Recommends getting enough potassium, noting that most people get too much sodium and not enough potassium.
    • 28 Apr 2025 · Taurine · neutral · YouTube ↗
      States that they do not use taurine for performance, acknowledging its benefits for mitochondrial health and longevity, as suggested by Bruce Ames, but finding performance literature mixed.
    • 29 May 2024 · Potassium · recommends · YouTube ↗
      States that maintaining a high potassium intake is important for hypertension.
  • Thomas DeLauer · Magnesium · uses
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 28 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's cans which contain 100 milligram potassium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 24 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's 100 mg potassium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 22 Oct 2026 · Taurine · recommends · YouTube ↗
      Recommends taurine, stating it raises the stress threshold, acts as a GABA and glycine receptor modulator, and protects neurons from stress, ultimately lowering cortisol release.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 25 Sep 2026 · neutral · Facebook ↗
      Mentions that magnesium in pumpkin seeds relaxes bronchial smooth muscle.
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares magnesium content, stating bananas have 32mg and pumpkin seeds have 156mg per ounce, a 5x difference.
    • 1 Sep 2026 · recommends · Instagram ↗
      Recommends Magnesium glycinate, stating that 200-400mg elemental helps with sleep as glycine cools the body and magnesium calms.
    • 29 Aug 2026 · neutral · Instagram ↗
      Notes that magnesium sits on the NMDA receptor and regulates excitatory transmission, in the context of feeling stressed.
    • 29 Aug 2026 · Potassium · recommends · YouTube ↗
      Recommends Element's ready-to-drink sparkling electrolyte drinks as a low or zero-calorie soda replacement that provides 1,000 milligrams of sodium, 200 milligrams of potassium, and 60 milligrams of magnesium.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 9 Oct 2026 · Taurine · neutral · Instagram ↗
      States that taurine supports normal muscle, nerve, and heart function, and supplement trials suggest benefits for some metabolic markers, exercise performance and blood pressure.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 7 Oct 2026 · Taurine · recommends · Instagram ↗
      Recommends Taurine for blood pressure and metabolic health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 6 Oct 2026 · Taurine · neutral · X ↗
      Lists Taurine as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 30 Sep 2026 · Potassium · neutral · X ↗
      Lists potatoes and fruit as sources of Potassium.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · Taurine · recommends · Instagram ↗
      Thinks taurine has some of the strongest evidence and is worth considering.
    • 4 Sep 2026 · Taurine · recommends · X ↗
      Recommends taurine for older people to support mitochondrial function and metabolic health.
    • 17 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
  • Andrew Huberman · Magnesium · neutral
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 27 Jul 2026 · Potassium · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 13 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 6 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 6 Jul 2026 · Coenzyme Q10 · uses · YouTube ↗
      Personally takes Omega-3 and Coenzyme Q10 every day, noting they are known to support cardiovascular health, cellular health and energy, and brain health.
    • 22 Jun 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 18 Jun 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 8 Jun 2026 · Coenzyme Q10 · uses · YouTube ↗
      Personally takes coenzyme Q10 every day, noting it supports cardiovascular health, cellular health, energy, and brain health.
    • 18 May 2026 · Potassium · uses · YouTube ↗
      Uses Element, which contains potassium in the correct ratios, to ensure proper hydration and electrolyte intake for brain and body function.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 6 Sep 2026 · Potassium · recommends · YouTube ↗
      States there is some evidence that increasing dietary potassium through potassium-rich foods like bananas and potatoes, rather than supplements, can lower blood pressure.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 15 Nov 2024 · Taurine · neutral · YouTube ↗
      Mentions that taurine supplementation in mice and other species appears to prolong life, referencing V.J. Adav's work, but notes that it is unclear if the same applies to humans.
    • 19 Aug 2024 · Taurine · neutral · YouTube ↗
      Mentions that taurine supplementation in mice and some other species appears to prolong life in VJ Addev's work, but it's unclear if the same applies to humans.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
    • 20 May 2024 · uses · YouTube ↗
      Takes magnesium as a straightforward supplement.
    • 28 Feb 2024 · neutral · YouTube ↗
      Mentions that magnesium intake is often super low and impactful on testosterone levels.
    • 11 Dec 2023 · uses · Facebook ↗
      Discusses the important roles of magnesium in the body, how to determine if one might be deficient, the prevalence of magnesium deficiency, and its potential cognitive benefits.
    • 25 Jun 2023 · Taurine · neutral · Facebook ↗
      A new study set off a media storm over taurine’s potential in delaying aging and extending lifespan, which is great news if you’re a mouse.

RAL Summary

Members OnlyTier 2 for Blood Pressure

Taurine, magnesium and coenzyme Q10 are at studied doses, and pooled analyses of randomized trials show modest drops in blood pressure for each. With 93% of 1175 reviews positive, this supports tier 2. The potassium cited by the rules is far below its studied dose, so it adds little.

Where the evidence disagrees: 68 of the 213 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Cardiovascular system

Combine with: Omega-3 (EPA/DHA) and CoQ10 have modest, supportive evidence for healthy blood pressure, with CoQ10 showing small systolic and diastolic reductions in some meta-analyses and omega-3s showing modest effects at higher doses. To strengthen blood pressure support, consider pairing with magnesium (glycinate or taurate, 200-400 mg), which helps relax vascular smooth muscle, and potassium-rich foods or a modest potassium supplement if approved by a clinician, since potassium counterbalances sodium. Aged garlic extract, beetroot or nitrate-based nitric oxide support, and hibiscus extract have clinical data for vasodilation and blood pressure. Taurine and L-citrulline or L-arginine may further support nitric oxide production. Vitamin K2 and vitamin D3 support vascular and arterial health. Pair with a low-sodium, DASH-style diet, regular exercise, and consult a doctor first if you take meds, meds, or meds, as omega-3s, CoQ10, garlic, and hibiscus can add to their effects or interact.

Possible side effects: No major side effects reported. One reviewer disliked the taste of the capsule.

Supplement Facts

Magnesium 200 mg · Potassium 95 mg · Taurine 900 mg
Supplement Facts
Serving Size 3 Capsule(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Magnesium200 mg
Potassium95 mg
Taurine900 mg†
Hawthorn Flowering Tops Extract350 mg†
Coenzyme Q-1045 mg†
† Daily Value not established.

Other ingredients: Hypromellose, Calcium Laurate.

Directions: Suggested Use: Take 3 capsules one to two times daily or as recommended by your health-care practitioner.

Barcode (UPC) 693749713029 · Label source: NIH label database · Report a label change

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Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.