Thorne Omega-3 with CoQ10 Review
Product Focus: CholesterolAlso covers:Heart
Tier ⓘ
Tier 4 · Rank 7
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 7 within Tier 4 for Cholesterol; 35 of 37 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
15 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Biohacker Mentions
0 of 10
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Study, Trial or Testing Result Summary
Members OnlyHuman studies
This product combines omega-3 fatty acids with coenzyme Q10, according to the store listing. For the goal of managing cholesterol, our research did not find any human studies on these ingredients that we could use to judge whether this product helps. That does not mean the product fails. It means we have no study findings in our records to show a clear benefit or a clear lack of benefit for cholesterol at this time. The label we have is also incomplete. It lists calories but not the amounts of omega-3 fatty acids or coenzyme Q10 in each serving, so we cannot compare the dose in this product with doses used in research. There are also no counted reviews and no written reviews we could read, so we know nothing about how people using it have found it. Our biohacker panel made no statements about it either. Until human studies on these ingredients for cholesterol are added and real user feedback builds up, this product stays in the emerging group. If you are thinking about taking it for cholesterol, talk with your doctor, especially if you already take cholesterol or meds. Animal and cell studies are never counted.
Review Totals and Summary
Members OnlyWhat buyers say
No written reviews read yet.
Biohacker Summary
Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it
Omega-3 fatty acids are listed as a smaller ingredient in this product, yet nearly the whole panel spoke about them, and most of the ten recommend or use them. Panelists take them for heart health and lower triglycerides, brain function, less inflammation, slower biological aging, fertility, skin, and muscle building. They favor fish oil or oily fish such as salmon and sardines, and one says to take omega-3s with a fat-containing meal to improve absorption. Doses range from about 1 gram a day to 2 to 4 grams a day of combined EPA and DHA, and one panelist warns that most people underdose because standard capsules hold little EPA and DHA. One panelist notes the research on hard heart disease outcomes is not very strong, and several stayed neutral, but none said they stopped. Only one panelist spoke about coenzyme Q10, another smaller ingredient in this product, saying he takes 300 mg daily for mitochondria and longevity and that meds lower it.
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Dr. Eric Berg · Omega-3 Fatty Acids · recommends
- Recommends wild-caught salmon as a healthy food to eat every day, noting it contains about 2000 mg of omega-3s in just 3 ounces.
- Recommends wild salmon as it is rich in omega-3 fatty acids, which help reduce inflammation and support brain health and cognitive function, especially important as one ages.
- Recommends DHA, an omega-3 fatty acid, as a natural remedy that, along with sweet wormwood, can trigger iron into an explosion to hit cancer.
- Dr. Eric Berg mentions that sardines are packed with omega-3 fatty acids, which support brain health and metabolism.
- Mentions that wild salmon, specifically half a fillet, has 970 mg of potassium, zero carbohydrates, a good amount of magnesium, and is loaded with omega-3 fatty acids.
- Mentions that grass-fed liver has coenzyme Q10.
- Discusses what would happen if one consumed omega-3 fatty acids every day for 30 days, highlighting their benefits for brain health, heart health, and various conditions like dry eyes, dermatitis, and high blood pressure, as well as supporting calcium absorption and promoting better sleep.
- Recommends getting plenty of omega-3 fatty acids to support joint and metabolic health.
- Recommends consuming foods rich in vitamin D, including fatty fish, to boost vitamin D levels.
- Recommends fatty fish as the best type of protein for inflammation.
- Recommends fatty fish, including salmon, mackerel, and sardines, as dietary sources of vitamin D.
- Recommends that anyone with a med prescription should also take coenzyme Q10, specifically the ubiquinol form, to support heart and muscle function.
- Notes that Merck filed a patent for a med combined with coenzyme Q10, but never added it back into the formula, and that major heart organizations do not recommend taking coenzyme Q10 alongside meds.
- Recommends taking coenzyme Q10, specifically ubiquinol, to prevent the side effects of meds, especially for those experiencing muscle weakness, pain, fatigue, or exercise intolerance. He suggests a dose of 200 to 400 mg, or even up to 1200 mg a day for some individuals.
Siim Land · Omega-3 Fatty Acids · recommends
- Recommends taking omega-3s, including EPA and DHA, with a fat-containing meal to increase absorption.
- Increased his omega-3 intake to achieve a higher omega-3 index, which is associated with greater insulin sensitivity and better metabolic health markers.
- Increased his omega-3 index to 9.5% and notes that omega-3s have strong evidence for reducing elevated triglycerides.
- Mentions that EPA and DHA Omega-3s support heart and brain function and can lower triglycerides, with a higher omega-3 index associated with lower heart disease, Alzheimer's and mortality risk.
- Recommends Omega-3s for triglycerides and cardiovascular health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
- Recommends choosing an omega-3 supplement from a brand that uses independent third-party testing and publishes a recent certificate of analysis, verifying EPA and DHA amounts, and testing for heavy metals, contaminants, and oxidation markers.
- Lists Omega-3s as one of 15 supplements backed by human studies.
- Explains that omega-3s can alter mitochondrial membranes and have broader cardiometabolic effects, making mitochondria more responsive to cellular signaling and oxidative stress from exercise, but they don't increase maximal mitochondrial respiration.
- Notes that 75% of people aren't meeting the daily recommendation for omega-3s and that Japanese people eat 2-3x more omega-3s per day than Americans or Europeans, which reflects in their higher omega-3 index.
- Thinks omega-3s have some of the strongest evidence and are worth considering.
- Describes Coenzyme Q10 as a mitochondrial supportive supplement that may increase energy production, but notes there isn't actual lifespan or longevity evidence for it.
- Takes 300 milligrams of Coenzyme Q10 daily as a supplement, noting it helps with energy production, fat oxidization, heart health, and longevity.
Andrew Huberman · Omega-3 Fatty Acids · recommends
- AG1 is giving away a free bottle of omega-3 coenzyme Q10 with your first subscription.
- Mentions that AG1 is giving away a free bottle of Omega-3 co-enzyme Q10 with the first subscription to AG1 Pro.
- Discusses Omega-3 Fatty Acids and EPA.
- Mentions that AG1 is offering a free bottle of Omega-3 co-enzyme Q10 with a first subscription to AG1 Pro.
- Recommends a free bottle of Omega-3 co-enzyme Q10 with the first AG1 Pro subscription.
- Mentions Omega-3s in the context of the microbiome and processed foods.
- Recommends Omega-3 co-enzyme Q10, which is offered as a free bottle with the first AG1 Pro subscription.
- States that getting 1 to 3 grams of EPA essential fatty acid per day can improve mood and cognitive function, supporting focus and concentration.
- Discusses Omega-3 Fatty Acids.
- Discusses omega-3s, artificial sweeteners, fructose, and fats.
- Personally takes Omega-3 and Coenzyme Q10 every day, noting they are known to support cardiovascular health, cellular health and energy, and brain health.
- Personally takes coenzyme Q10 every day, noting it supports cardiovascular health, cellular health, energy, and brain health.
- Discusses a study where probiotics, magnesium orotate, and coenzyme Q10 showed a short-term improvement in symptoms of major depression.
- Discusses Coenzyme Q10 as a fertility supplement.
Thomas DeLauer · Omega-3 Fatty Acids · recommends
- Recommends fish oil supplements as an omega-3 source for gut health, as they help reduce inflammatory signaling while tissue repairs.
- Recommends high-dose omega-3s, specifically 2 to four grams of combined EPA and DHA daily, to lower hepatic fat output and improve chylomicron clearance, which helps with non-fasting triglycerides.
- Recommends omega-3s, specifically 4 grams a day, to boost the muscle building response by making muscle cell membranes work better for the mTor switch to fire, and specifically mentions Pury for their clean, third-party tested omega-3s.
- Recommends consuming more omega-3s to help balance the mitochondrial membrane, as it will absorb more omega-3s instead of omega-6s.
- Recommends consuming more omega-3s to drive down inflammation.
- Recommends omega-3s, stating that a meta-analysis found 1,000 mg significantly reduced liver fat by shutting down inflammatory signals that promote fat storage, and advises looking for a triglycerol form for better absorption and to avoid oxidation.
- Recommends fatty fish like salmon and sardines, aiming for two to three servings per week, especially around a workout, because their omega-3s, particularly DHA, increase BDNF expression.
- Considers omega-3s a fundamental for brain protection, recommending both dietary sources and supplementation for EPA and DHA, as they produce pro-resolving mediators to limit inflammation.
- Recommends timing omega-3 intake around workouts because they directly help build and keep muscle by making muscle more responsive to growth signals and fighting anabolic resistance as one ages.
- Notes that Scandinavians consume fatty fish multiple times a week as part of their diet, contributing to their long lifespan and healthspan.
- States that coenzyme Q10 is one of his favorite compounds for the mitochondria, and it is found in sardines.
- Recommends getting coenzyme Q10 from good quality red meat and organ meat, or through supplementation, to act as an electron catcher in the mitochondria, optimizing energy production and reducing oxidative stress.
- Recommends utilizing coenzyme Q10 to support mitochondrial function and the electron transport chain, making hydration more effective.
- Recommends coenzyme Q10 as a runner-up for energy and mitochondrial function, explaining it's an electron carrier in the mitochondrial chain that focuses on the last complex, creating a bigger net to catch electrons and reduce oxidative stress.
Dave Asprey · Omega-3 Fatty Acids · recommends
- Suggests that omega-3s may help slow aging and support cellular repair.
- Recommends omega-3s, noting that 1 gram a day slowed epigenetic aging by up to 4 months in a randomized trial of people over 70.
- States he takes 300 mg of Coenzyme Q10 every day for 20 years because it is necessary for mitochondria to function and is important for longevity, noting that meds lower it.
- Dave Asprey recommends Omega-3, citing a randomized trial showing 1g a day slowed epigenetic aging in older adults, but warns that most people underdose due to low EPA and DHA content in standard capsules.
- A review of 41 human studies testing interventions against newer-generation epigenetic clocks found favorable changes for exercise, caloric restriction, omega-3s, plant-rich diets, multivitamins, a med, pitavastatin, and ketamine.
- Recommends getting nutrients like omega-3s from real food or Vision 101 for eyesight.
- Recommends adding omega-3 fats to improve how neurons absorb and use nutrients like vitamin C.
- Recommends coenzyme Q10 (CoQ10) to support mitochondria, as it helps generate energy and fights oxidative stress.
- States that Fatty15 supports cells better than omega-3s or fish oil, but he uses both.
- Notes that Inuit people consumed very high levels of omega-3s, specifically EPA and DHA, which contributed to their health on a whale blubber diet.
- Lists Omega-3s as a nutrient that forms the structure and different parts of the brain.
- Uses both C15 and omega-3s, noting that C15 supports cells better than omega-3s or fish oil with three times more benefits.
- Mentions that there are methylation genes for Coenzyme Q10 that convert it to ubiquinol.
- Suggests taking Coenzyme Q10 to optimize mitochondria.
Dr. Rhonda Patrick · Omega-3 Fatty Acids · neutral
- Mentions that EPA is an omega-3 examined in mortality analysis and found primarily in seafood.
- States that Omega-3 fatty acids are very important for sperm health.
- Omega-3s may help slow biological aging, with added benefits when combined with vitamin D and strength training. In a 3-year randomized trial of healthy, mostly active older adults, omega-3 alone slowed several DNA-based aging clocks.
- Recommends regular intake of omega-3 rich seafood and supplementation with omega-3 fatty acids if it's appropriate for one's lifestyle, as they are beneficial for the heart by resolving inflammation and preserving membrane fluidity.
- Notes that a 100 mg per day increase in omega-3 fatty acids was associated with lowering the risk of Alzheimer's disease and cognitive decline by 10%, and that it takes about two grams a day to get to a high omega-3 index if one has a low index.
- Practical habits to help keep chronic inflammation in check include getting enough omega-3s.
- States that Omega-3s, specifically EPA and DHA, may be the most potent naturally occurring dietary compounds for reducing inflammation, and that about 2 g/day of combined EPA and DHA can raise a low omega-3 index.
- Recommends fatty fish as a source of healthy fats for muscle gain.
- Mentions that an omega-3 supplement might not be working, and one would not know without taking the Omega-3 index test.
- Recommends considering omega-3s to improve mood.
- A daily dose of coenzyme Q10 reduces blood pressure by about 4mmHg systolic and 3mmHg diastolic in people with type 2 diabetes, potentially lowering cardiovascular risk.
Dr. Mark Hyman · Omega-3 Fatty Acids · neutral
- Mentions omega-3 fats as existing biomarkers that play a role in mental health, which Function Health includes in their measurements.
- Mentions that omega-3s are anti-inflammatory and helpful.
- Tries to supplement with omega-3s for psoriasis and considers them the one clearly clinically effective skin nutrient for skin, hair, and nails.
- Emphasizes the importance of focusing on omega-3s, noting that a national crisis of omega-3 deficiency exists and that low omega-3 levels are a significant problem, more so than omega-6s.
- Consumes omega-3 fats through salmon at dinner.
- Notes that omega-3s are important nutrients for brain performance and aging, and that many people have gaps in these nutrients.
- Recommends omega-3 fats from wild fish, seafood, and certain nuts and seeds to fight inflammation.
- Mentions omega-3 fats as something that might be helpful for gut repair.
- Used omega-3 fats as part of a protocol to rebuild the gut microbiome and heal the gut of a nine-year-old girl with severe behavioral issues.
- States that omega-3 fats from fatty fish, flax, and walnuts help balance inflammatory pathways, but no supplement can replace daily signals from sleep, nutrition, exercise, stress management, and metabolic health.
- Mentions that coenzyme Q10 is important in mitochondrial function and can be a factor in migraines.
- Tried coenzyme Q10 as part of a meticulous effort to address energy and metabolism issues, but implies they no longer use it as they were looking for an easier solution.
- Included coenzyme Q10 in a mitochondrial rejuvenation program to support mitochondrial function.
- States that mitochondria need coenzyme Q10 and that PQQ has been shown to work very well with it.
Ben Greenfield · Omega-3 Fatty Acids · neutral
- Notes that omega-3s have solid research behind them for fertility.
- Recommends omega-3 fatty acids, specifically EPA and DHA, at 1 to 3 grams per day for better sperm morphology and motility, noting that sperm membranes are rich in polyunsaturated fatty acids.
- Recommends getting Omega-3 from oily fish such as sardines, anchovies, mackerel, herring, and salmon with skin.
- Discusses why fatty fish or fish oil may matter more than plant-based omega-3s if seed oils are in one's diet.
- Says that omega-3 fatty acids are a great way to feed the system and help with stress.
- Recommends testing for and replenishing omega-3 fatty acids if levels are low, as they can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
- Recommends including EPA from fatty fish or fish oil in one's diet, especially if seed oils are present in the diet.
- Notes that B vitamins and Omega-3s work as a pair to support the brain, but not independently.
- Notes that the DO-Health study showed omega-3 had good effects, and it's a supplement people commonly take.
- Mentions that omega-3, vitamin D, and exercise all had good effects in the DO-Health study.
- Discusses Coenzyme Q10 as an ingredient that MitoQ uses in a mitochondria-directed form, noting that standard CoQ10 rarely achieves movement past the cell membrane and into mitochondria.
- Discusses Coenzyme Q10 (CoQ10) in the context of MitoQ Pure being an upgraded form of it.
- Is currently using CoQ10 because any type of a med, including natural ones like red yeast rice extract, can deplete the body's coenzyme Q10 levels, affecting mitochondrial health.
- Is a big proponent of crystal-free coenzyme Q10, explaining that most CoQ10 products have poor absorption due to crystallization, and recommends Pharma Nord's patented process for keeping CoQ10 in solution, which achieves three to ten times higher plasma levels.
Peter Attia · Omega-3 Fatty Acids · neutral
- Peter and Michael explore the benefits of omega-3 fatty acids for cardiovascular trials and the challenge of delivering DHA to the brain.
- Mentions that some trials showing a benefit to PUFA were confounded by the inclusion of omega-3s, and argues that the literature on omega-3s is not super strong for decreasing hard cardiovascular disease endpoints.
- Took big doses of omega-3 postpartum to help maintain when she wasn't sitting down to eat full meals.
- Mentions consuming fatty fish, specifically sardines, as part of their diet, noting their high fat and protein content.
- Peter discusses how omega-3s from fish oil impact inflammation, heart health, and brain function, as well as the strengths and limitations of current research.
- Mentions the importance of DHA omega-3 fatty acids for neuronal membranes, which are concentrated in synapses and crucial for communication between neurons.
- Highlights the importance of DHA omega-3 fatty acids for neuronal membranes and communication between neurons, as they are concentrated in synapses.
- Discusses the mfsd2a transporter, which is specific to DHA in phospholipid form, and its role in blood-brain barrier integrity, noting that animal studies show disruption of this transporter causes significant breakdown of the blood-brain barrier and loss of omega-3 in the brain.
- Notes there isn't good data that Coenzyme Q10 prevents a med Associated muscle symptoms, but doesn't object if patients want to take it because it makes them feel better about taking a med.
- States that there is a very strong clinical impression that high doses of omega-3s help with dry eye, primarily from an anti-inflammatory standpoint.
- Recommends omega-3 fatty acids, specifically DHA and EPA, for brain protection, especially for individuals with the APOE4 gene, stating that they require higher doses.
Bryan Johnson · Omega-3 Fatty Acids · recommends
- Recommends Omega 3 fatty acids as a supplement for skin health, noting they are in the Blueprint stack.
- During menopause, Bryan Johnson recommends ensuring adequate omega-3s for brain health.
RAL Summary
Members OnlyTier 4 for Cholesterol
It is rated emerging because we found no human studies on its ingredients for cholesterol and it has no reviews, so the evidence is too thin to rank it higher.
- Emerging: not enough evidence to rank higher yet.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system
Possible side effects: No major side effects reported.
Supplement Facts
Total Omega-3 Fatty Acids 700 mg · Coenzyme Q10 30 mg
Supplement Facts
Serving Size 1 Gelcap(s)
Servings Per Container 90
Amount Per Serving% Daily Value
| Calories | 10 | |
| Total Fat | 1.5 g | |
| Total Omega-3 Fatty Acids | 700 mg | † |
| Coenzyme Q10 | 30 mg | † |
† Daily Value not established.
Other ingredients: Bovine Gelatin, Water, Purified, Glycerin, Vitamin E.
Directions: Suggested Use: Take 1 gelcap two to three times daily or as recommended by your health-care practitioner.
Barcode (UPC) 693749616030 · Label source: NIH label database · Report a label change
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Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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