Thorne Research Radiant Skin Complex Review

Radiant Skin Complex is a Thorne Research skin support supplement presented as a way to enhance natural aesthetic with cellular support for skin hydration and collagen integrity. The product is described as promoting smoother, softer skin with antioxidant-rich botanicals, hyaluronic acid, and eggshell nutrients that help fortify the skin barrier and reduce the appearance of fine lines and wrinkles. The page states that the product carries NSF Certified for Sport. The listed key ingredients are OVOLUX Eggshell Membrane, the eternalyoung Botanical Blend, and Hyaluronic Acid. Each serving is two capsules, and the container holds 30 servings, which the page describes as a simple once-daily, two-capsule serving. The ingredient amounts listed are 400mg of OVOLUX Eggshell Membrane, 225mg of eternalyoung Botanical Blend, and 120mg of Hyaluronic Acid. Other ingredients include a hypromellose capsule, microcrystalline cellulose, and ascorbyl palmitate. The page explains that Ovolux is a patented, sustainably sourced ingredient that extracts nutrients from eggshell membrane and that it uses unhydrolyzed eggshell, which the brand says shows enhanced bioactivity compared with hydrolyzed forms. The eternalyoung blend is described as a mix of pomegranate, sweet orange, Cistanche, and gotu kola, which the page links to antioxidant support, protection against free-radical damage, a healthy inflammatory response in the skin, and visible reduction of fine lines within about four weeks. Ovolux is described as supporting skin elasticity and firmness in as little as six weeks and as enhancing overall skin appearance after twelve weeks. The page lists benefits including reducing fine lines and wrinkles, promoting hydration, supporting elasticity and firmness, supporting even texture and tone, and helping to maintain collagen integrity. It is aimed at adults seeking alternatives or complements to topical skincare, people with early signs of skin aging, women and men who want to maintain healthy skin, perimenopausal and postmenopausal women, and people with loose skin after weight loss. The page advises pairing the product with collagen supplements such as Thorne Collagen Plus. The warnings state that the product is contraindicated for anyone with a history of hypersensitivity to its ingredients, that it contains an ingredient derived from egg, and that anyone who is pregnant, nursing, or trying to conceive should not use it. The page reports no known adverse interactions at publication date.

Tier ⓘ
Tier 3 · Rank 8
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 8 within Tier 3 for Younger-Looking Skin for Women; 29 of 40 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
67 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
81% of 85
Biohacker Mentions
9 of 10
Cost per month
$49

Study, Trial or Testing Result Summary

Members Only36 human studies · 32 improved

12 of these 36 human studies gave the ingredient by injection, not by mouth.

36 human studies32 improved2 no effect3,901 people studied

Eggshell membrane, at 400 milligrams here, has the best support. In a trial of 88 middle-aged adults, 450 milligrams a day for 12 weeks improved the look of crow's feet wrinkles by week 4 and skin tone by week 8 compared with a dummy pill [1]. Another trial found 300 milligrams a day for 57 days improved skin firmness, flexibility and elasticity more than a dummy pill or a large dose of collagen [2]. The eternalyoung blend of rosemary and grapefruit extracts, at 225 milligrams here, reduced sun-caused skin redness at 100 or 200 milligrams in one small trial of 20 adults, but wrinkles and moisture were not measured [3]. For hyaluronic acid taken by mouth, a pooled analysis of 7 trials found better skin hydration, elasticity and wrinkle depth [4]. However, one trial in 87 women found adding it to collagen gave no extra benefit [5]. Whether the 120 milligrams here matches the studied doses is unclear. Most other hyaluronic acid studies tested injected fillers or creams, which do not apply to capsules [6]. The calcium studies tested calcium injected into the skin as a filler, so they say nothing about the small 52 milligram amount in this capsule [7]. Animal and cell studies are never counted.

See all 36 studies →Hide the studies

Review Totals and Summary

Members Only85 reviews · 81% positive
85 reviews · Thefeed 25 · Covenanthealthproducts 25 · IHerb 17 · Thorne 15 · Amazon 3
81% positive3% neutral16% negative

**Overall:** Across the stores the product carries about 35 ratings. The written feedback is mostly positive and centers on skin appearance, though the ratings are more mixed than the comments, and the reasons for the lower ones aren't visible. **What buyers say it did for them:** Most say they saw a change in their skin, often described as a glow. Timing ranges from one week to three months. One buyer writes, "I noticed the results after a week and my skin is glowing!" Another says the difference is "Not just on my face, but all over." A third says, "I notice a difference in my skin texture and appearance." One also mentions a difference in hair, and another credits it with helping their joints and general health. **Mixed or lukewarm experiences:** Some buyers are more tentative. One has taken it for a month and says, "I don't notice anything drastic but my skin feels nice." A second-bottle buyer says, "I'm not sure if it's helping," and plans to keep taking it anyway. The store page shows lower star ratings (three at 3 stars or below) but no text explaining them, so the reasons for those are unknown. No written review complains of side effects, aftertaste, capsule size or price. **Taste, smell, pill size, form:** Taste gets one positive mention: "Love the taste and the way it helps my health." Another reviewer says the company's products are always good in "quality, dosage and size," a general remark about the brand rather than this product alone. Nobody reports problems with swallowing the capsules. Reviews of other forms of the product were left out, and this summary covers the capsules only. **Value for money:** Nobody comments on price, so there is nothing in the feedback to say whether it is good value. Repeat purchase is the only hint: one buyer is on a second bottle, and another says they will use it regularly. **Who it seems to suit and who it did not:** It seems to suit people who already trust Thorne and are looking for a skin-focused supplement, and who are willing to take it for a few weeks to a few months. One reviewer calls Thorne "one of my favorite company of vitamins." Those hoping for dramatic results may be disappointed, since some buyers describe only subtle effects or are unsure of any effect. The feedback doesn't identify any group for whom it clearly failed, and the unexplained lower star ratings leave that question open. **Bottom line:** Buyers who report results mostly describe a nicer, glowier look to the skin, sometimes within a week and sometimes taking longer. A few are unsure it does anything. The written feedback raises no concerns about taste, size or side effects, but it also doesn't speak to price.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Only one panelist spoke about eggshell membrane, the main ingredient, and he recommends it, noting that a collagen product contains it and that it has been shown to support joint function. No one else on the panel addressed it, so there is little to go on for forms, doses or pairings. Calcium, a smaller ingredient in this product, drew the most comment: several recommend it for bone health, one suggests 1,000 to 1,200 milligrams a day from food and supplements, and others prefer getting it from foods like sardines and leafy greens. Two of them warn against supplemental calcium, one citing kidney stones and one citing hardening of the arteries, and one keeps multivitamins low in calcium. Hyaluronic acid, also a smaller ingredient in this product, is mostly recommended for skin hydration, with one panelist taking 300 milligrams a day for joints.

See all 10 biohackers →Hide the biohackers
  • Siim Land · Eggshell Membrane · recommends
    • 18 Jun 2024 · recommends · YouTube ↗
      Highlights that Nordic Kodo collagen has eggshell membrane, which has been shown to support joint function.
    • 30 Sep 2026 · Calcium · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 14 Aug 2026 · Calcium · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 28 Jul 2026 · Hyaluronic Acid · neutral · Instagram ↗
      Notes that red light therapy increases hyaluronic acid in the skin, which supports skin elasticity.
    • 27 Jul 2026 · Hyaluronic Acid · neutral · YouTube ↗
      Notes that the addition of 30 mg of hyaluronic acid provided some small additional benefits for skin health when combined with vitamin C and hydrolyzed collagen.
    • 12 Jun 2026 · Hyaluronic Acid · neutral · YouTube ↗
      Notes that there are a few clinical trials on hyaluronic acid reducing skin wrinkles and dryness, but a smaller amount of studies compared to collagen.
    • 30 May 2026 · Hyaluronic Acid · neutral · Instagram ↗
      States that red light therapy increases hyaluronic acid in the skin, which supports skin elasticity.
    • 28 Apr 2026 · Hyaluronic Acid · neutral · Instagram ↗
      States that red light therapy increases hyaluronic acid in the skin, which supports skin elasticity.
    • 14 Feb 2026 · Calcium · recommends · TikTok ↗
      Recommends a high calcium intake for bone health.
    • 28 Dec 2025 · Calcium · warns · YouTube ↗
      Places calcium supplementation in the 'bad tier' due to its association with increased cardiovascular events, recommending dairy or bones as easier ways to get calcium, though it can be useful for postmenopausal women with low bone density.
    • 28 Dec 2025 · Hyaluronic Acid · warns · YouTube ↗
      States that topical hyaluronic acid lacks evidence for skin benefits because it doesn't get absorbed well, although some newer products have modified molecular structures to improve absorption.
    • 13 Dec 2025 · Hyaluronic Acid · uses · YouTube ↗
      Includes hyaluronic acid in his 'all out' supplement stack.
    • 11 Dec 2025 · Hyaluronic Acid · recommends · YouTube ↗
      Recommends hyaluronic acid for skin anti-aging, noting it helps with skin hydration.
    • 6 Oct 2025 · Calcium · neutral · YouTube ↗
      Mentions that eating enough calcium matters for bone density, but states that it alone won't transform bone density.
  • Dr. Mark Hyman · Hyaluronic Acid · recommends
    • 28 Oct 2026 · recommends · YouTube ↗
      Likes working with Pique for healthy skin, specifically their Radiant Skin Duo, which combines BT Fountain (electrolytes, ceramides, hyaluronic acid) and Sun Goddess Matcha (antioxidants, L-theanine) to support hydration and skin barrier from the inside.
    • 7 Oct 2026 · recommends · YouTube ↗
      Mentions hyaluronic acid as a nice hydrating ingredient.
    • 20 Aug 2026 · Calcium · recommends · YouTube ↗
      Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
    • 17 Jun 2026 · Calcium · neutral · YouTube ↗
      States that green leafy vegetables are great sources of calcium.
    • 3 Nov 2025 · Calcium · neutral · Podcast ↗
      Notes that calcium needs are lower than advertised and that stress, soda, and excess sugar can drive calcium loss.
    • 17 Sep 2025 · Calcium · warns · YouTube ↗
      Does not prescribe calcium supplements at all, teaching people to get it from whole foods instead, because calcium supplements don't work for building bones or preventing fractures, and it's bone quality, not density, that matters.
    • 14 May 2025 · Calcium · warns · YouTube ↗
      Warns that acid blockers inhibit calcium absorption.
    • 2 Apr 2025 · Calcium · recommends · YouTube ↗
      Lists calcium as another important nutrient that people can be tested for and measured.
    • 12 Mar 2025 · Calcium · warns · YouTube ↗
      States that high doses of calcium supplementation in the elderly were not really impacting bone density, as osteopenic patients still became osteoporotic.
    • 29 Nov 2024 · Calcium · warns · YouTube ↗
      Warns that meds (meds) impair the absorption of calcium, which increases the risk of hip fractures and osteoporosis.
    • 15 Nov 2024 · Calcium · recommends · YouTube ↗
      Recommends calcium citrate, about 600 milligrams a day, for bone health, noting that much can also be obtained from diet through leafy greens, sesame seeds, tahini, and chia seeds.
    • 27 Sep 2024 · Calcium · warns · YouTube ↗
      Dr. Hyman notes that while calcium deficiency is not common in terms of blood levels, insufficient intake can lead to osteoporosis as the body pulls calcium from bones. He advises caution with calcium supplementation due to potential heart issues.
    • 8 Jun 2020 · neutral · YouTube ↗
      Dr. Hyman mentions hyaluronic acid as a lubricant used in traditional orthopedic treatments for osteoarthritis.
  • Dr. Eric Berg · Calcium · warns
    • 25 Oct 2026 · warns · YouTube ↗
      Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
    • 10 Oct 2026 · warns · Podcast ↗
      Dr. Berg includes calcium carbonate among the synthetic supplements to avoid.
    • 3 Oct 2026 · warns · YouTube ↗
      Warns against calcium carbonate, also known as limestone, stating that while it lowered hip fractures in a study, it also increased kidney stones and is not good for arteries, requiring the body to work hard to use it.
    • 27 Sep 2026 · neutral · X ↗
      Notes that tannins in tea bind calcium, blocking its absorption.
    • 10 Sep 2026 · neutral · Facebook ↗
      Indicates that horizontal thin white lines near the base of the nails are indicative of low calcium.
    • 4 Sep 2026 · warns · Facebook ↗
      Warns that calcium carbonate can build up in the arteries and kidneys and increase the risk of a heart attack.
    • 3 Sep 2026 · neutral · Facebook ↗
      Dr. Berg mentions that fermented dairy contains vital nutrients, including calcium.
    • 3 Sep 2026 · neutral · Instagram ↗
      States that calcium and magnesium are intrinsically linked and work in combination with vitamin D to support the body's calcium balance.
    • 17 Aug 2026 · neutral · Facebook ↗
      Explains that calcium triggers muscle contraction, while magnesium is needed to relax the muscles afterward.
    • 9 Aug 2026 · warns · YouTube ↗
      Warns that too much calcium can cause high blood pressure by causing arterial contraction.
    • 11 Apr 2026 · Hyaluronic Acid · warns · YouTube ↗
      Notes that hyaluronic acid, while a natural remedy for skin hydration, only works on a superficial layer and does not address the root cause of facial aging, which involves muscles and bones.
    • Date not recorded · Hyaluronic Acid · recommends · Website ↗
      Dr. Berg recommends prioritizing foods rich in hyaluronic acid or those that support its production, such as bone broth, organ meats, chicken skin, nuts, seeds, or snow mushrooms, to add moisture and boost skin hydration.
  • Bryan Johnson · Hyaluronic Acid · recommends
    • 6 Oct 2026 · recommends · YouTube ↗
      Considers hyaluronic acid essential for their routine, stating it retains moisture, giving the skin extra firmness and texture, and helps counteract the decrease in levels that occurs with age, leading to dehydrated skin.
    • 28 Aug 2025 · uses · YouTube ↗
      Uses hyaluronic acid as part of his nighttime skincare routine.
    • 5 Jun 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
    • 12 May 2025 · Calcium · recommends · YouTube ↗
      Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
    • 21 Jun 2023 · uses · YouTube ↗
      Takes 300 milligrams of hyaluronic acid a day for joint health.
    • Date not recorded · Calcium · recommends · Website ↗
      Recommends prioritizing calcium intake for postmenopausal women to help maintain bone density and reduce the risk of osteoporosis.
    • Date not recorded · Calcium · uses · Website ↗
      Bryan Johnson takes Calcium daily as part of his Longevity Mix, which supports healthy bones and teeth.
    • Date not recorded · Calcium · recommends · Source ↗
      Recommends continuing with calcium to support bone health during the follicular phase.
  • Thomas DeLauer · Calcium · neutral
    • 18 Sep 2026 · neutral · Facebook ↗
      Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
    • 12 Aug 2026 · recommends · YouTube ↗
      Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
    • 30 Jun 2026 · neutral · YouTube ↗
      Explains that eating sardines with their soft bones provides a serious hit of calcium, which is a perfect combination for bones and may contribute to satiety.
    • 19 Jun 2026 · neutral · YouTube ↗
      Mentions that magnesium and calcium should not be taken together as they cancel each other out.
    • 13 Jun 2026 · warns · YouTube ↗
      Tries to get multivitamins without calcium or with a low amount, as he believes supplemental calcium impacts the absorption of other vitamins and minerals and is not as beneficial as hyped. He cautions against it for most people due to the risk of coronary artery calcification.
    • 12 Jun 2026 · recommends · YouTube ↗
      Recommends getting calcium from dairy sources like milk, yogurt, kefir, and cheese in the morning to support neurotransmitter synchronization crucial for deep and REM sleep, noting that low dietary calcium is linked to insomnia.
    • 20 May 2026 · warns · YouTube ↗
      Warns that calcium competes with magnesium for the same absorption channels, advising to separate magnesium intake from calcium supplements or dairy by at least an hour or two.
    • 2 May 2026 · recommends · YouTube ↗
      Recommends providing the body with adequate dietary calcium, not a calcium supplement, to ensure a clean, strong spark for efficient insulin release.
    • 10 Apr 2026 · warns · YouTube ↗
      Warns that calcium and magnesium should not be taken together as they cancel each other out, though some products use delayed absorption to mitigate this.
    • 22 Mar 2026 · warns · YouTube ↗
      Warns that most people consume too much calcium relative to magnesium, which can disrupt the balance needed for proper bodily function, comparing it to an electrical circuit.
    • 12 May 2020 · Hyaluronic Acid · recommends · YouTube ↗
      Recommends supplementing with hyaluronic acid, noting its role in collagen formation by providing an elastic component and drawing water for supple, smooth, and flexible skin and hair.
    • 29 May 2019 · Hyaluronic Acid · recommends · YouTube ↗
      Explains that hyaluronic acid draws moisture into the collagen matrix, making it flexible and functional, and recommends it for supporting collagen production.
  • Dave Asprey · Hyaluronic Acid · recommends
    • 28 Jul 2026 · recommends · YouTube ↗
      Explains that hyaluronic acid is gradually laid down through access points in the shaft for girth enhancement, using six syringes of filler per treatment. He notes that the body slowly absorbs it, and men usually need a top-off every 18 months to maintain their goal girth.
    • 16 Jun 2026 · neutral · YouTube ↗
      States that he hardly ever uses a moisturizer and doesn't believe topical hyaluronic acid is necessary to make skin look good if it's not dry.
    • 16 Jun 2026 · Calcium · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
    • 12 Jun 2026 · Calcium · neutral · Instagram ↗
      Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
    • 12 Jun 2026 · Calcium · neutral · X ↗
      Notes that people take calcium for their bones.
    • 14 May 2026 · Calcium · warns · YouTube ↗
      Warns that taking calcium without vitamin D, A, and K2 can lead to calcium going into tissues, causing bone spurs and other issues, and recommends a two-to-one ratio of calcium to magnesium.
    • 30 Dec 2025 · Calcium · recommends · YouTube ↗
      Recommends taking calcium citrate during a high oxalate meal to bind the oxalate in the gut.
    • 21 Oct 2025 · Calcium · neutral · YouTube ↗
      Notes that people often take calcium for bone health.
    • 5 Aug 2025 · Calcium · warns · YouTube ↗
      Believes calcium supplements are overrated, as most people need more vitamin K2 and vitamin D instead.
    • 10 Jul 2025 · recommends · YouTube ↗
      Advises looking into rehydrating skin with hyaluronic acid eventually.
    • 2 Aug 2024 · Calcium · recommends · YouTube ↗
      Advises taking iron and calcium separately because they will bind together.
    • 16 May 2024 · uses · YouTube ↗
      Uses hyaluronic acid in his osteoarthritis patients, especially before regenerative procedures, to get cells into a better state by blocking inflammation.
    • 22 Apr 2024 · Calcium · uses · YouTube ↗
      Takes extra calcium to help deal with the burden when eating chocolate or anything with higher levels of oxalates.
    • 25 Jan 2024 · Calcium · neutral · YouTube ↗
      Discusses calcium citrate as a counter to oxalate crystals, specifically when consumed through dairy, but questions if it's the primary form of calcium in dairy.
  • Dr. Rhonda Patrick · Calcium · neutral
    • 29 Jun 2026 · neutral · Facebook ↗
      Mentions that kale delivers calcium, a micronutrient many diets fall short on.
    • 9 Jan 2026 · neutral · Facebook ↗
      Notes additional gaps in calcium.
    • 3 Jul 2024 · warns · YouTube ↗
      Reports that alcohol use disorder is associated with a 20-50% greater prevalence of Calcium deficiency.
    • 9 Oct 2015 · neutral · YouTube ↗
      Around 38% doesn't meet the requirement for calcium.
    • 11 Feb 2015 · uses · YouTube ↗
      Takes a calcium-magnesium pill because he believes people tend to be short of both and that the body cares about the ratio of these similar molecules.
    • Date not recorded · recommends · Website ↗
      States that 1,000 milligrams of calcium per day is the recommended intake for bone density, and supplementation is an option if this requirement is not met.
    • Date not recorded · uses · Website ↗
      Takes a calcium, vitamin K2, and vitamin D combination supplement in the morning, providing about 600 mg of calcium and another 1,000 IUs of vitamin D.
    • Date not recorded · neutral · Website ↗
      Dr. Rhonda Patrick discusses calcium needs.
    • Date not recorded · Hyaluronic Acid · neutral · Website ↗
      Dr. Rhonda Patrick explores oral hyaluronic acid.
  • Ben Greenfield · Hyaluronic Acid · uses
    • 11 Jun 2026 · uses · YouTube ↗
      Combined hyaluronic acid with exosomes and did a full facial.
    • 21 May 2026 · recommends · YouTube ↗
      Recommends a hyaluronic acid serum after applying hypochlorous acid because hypochlorous acid can be drying, and hyaluronic acid is a hydrating molecule that works well with it.
    • 9 May 2026 · Calcium · neutral · YouTube ↗
      Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
    • 6 May 2026 · Calcium · neutral · X ↗
      Mentions calcium as a common deficiency.
    • 12 Apr 2026 · Calcium · recommends · Facebook ↗
      Recommends adequate intake of calcium for bone strength.
    • 13 Feb 2026 · Calcium · uses · YouTube ↗
      Is using calcium chloride mixed with PRP before injecting for the P-shot.
    • 31 Jan 2026 · neutral · YouTube ↗
      Mentions that hyaluronic acid is involved in the Wing Lift protocol.
    • 22 Nov 2025 · Calcium · stopped · YouTube ↗
      Advises people to stop taking calcium supplements as part of the Root Cause Protocol.
    • 21 Aug 2025 · Calcium · warns · Facebook ↗
      Warns that in high doses, calcium without the right cofactors can raise cardiovascular risk by contributing to arterial calcification instead of bone strength, and may increase the risk of osteoporosis.
    • 3 Apr 2025 · Calcium · warns · YouTube ↗
      Explains that 10X separates calcium and zinc into different micro beads, releasing them at different rates and locations in the digestive tract to prevent competition and optimize absorption.
    • 31 Jan 2025 · recommends · YouTube ↗
      Recommends using hyaluronic acid after sun exposure to maintain overall skin health.
    • 26 Dec 2024 · Calcium · neutral · TikTok ↗
      Covers calcium as a key supplement for kids.
    • 27 Apr 2024 · warns · YouTube ↗
      Ben's guest, Dr. Cameron Chestnut, warns that hyaluronic acid fillers are often misused and misunderstood, as they last for decades rather than months, leading to problematic gel collection and migration.
    • 11 Apr 2024 · Calcium · warns · YouTube ↗
      Warns of calcium deficiency on a carnivore diet, as there is not an appreciable amount in meat, and recommends eating fish with bones or taking a calcium supplement or bone mineral matrix.
  • Peter Attia · Calcium · recommends
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 6 Jul 2025 · neutral · YouTube ↗
      Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
    • 22 Oct 2024 · recommends · YouTube ↗
      Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
    • 21 Oct 2024 · recommends · YouTube ↗
      Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
    • 1 Aug 2023 · Hyaluronic Acid · neutral · YouTube ↗
      Notes that hyaluronic acid injections are doing better than cortisone for joint pain, and that combining hyaluronic acid with PRP seems more effective than other treatments, though not astronomically so.
    • 31 Jul 2023 · Hyaluronic Acid · neutral · YouTube ↗
      Mentions that hyaluronic acid injections are another treatment option that performs better than cortisone over a year.
    • 30 Jul 2023 · Hyaluronic Acid · uses · YouTube ↗
      Says he would give hyaluronic acid in the hip, even though it's not FDA approved for that application, as it can be used off-label and some studies suggest it can help.
    • 18 Jul 2022 · neutral · YouTube ↗
      Notes that bone is 50 to 70 percent mineral, with calcium being the predominant mineral, and virtually all of the body's calcium is contained within bone.
    • 26 Oct 2020 · recommends · YouTube ↗
      Recommends getting about a gram of calcium a day from organic bone meal, which provides calcium hydroxyapatite, the form humans are meant to consume.
    • 12 Jan 2020 · neutral · YouTube ↗
      Suggests that calcium is one of the other signals involved in regulating mitochondrial number, beyond AMPK activation.
    • 7 Jan 2020 · warns · YouTube ↗
      States that in postmenopausal women not on estrogen, calcium and vitamin D have no protective effect against hip fracture because the problem is not the shell of the bone, which is fed by calcium and vitamin D, but the internal girder network.
    • 22 Dec 2019 · Hyaluronic Acid · neutral · YouTube ↗
      Peter Atia discusses hyaluronic acid fillers, noting they are a constituent of skin, very safe, biocompatible, and reversible with an enzyme.
    • Date not recorded · neutral · Website ↗
      Notes that compelling evidence links calcium to reduced risk of osteoporosis, which can impact mortality from specific causes.
  • Andrew Huberman · Hyaluronic Acid · neutral
    • 1 Jul 2024 · neutral · Instagram ↗
      Reviews data on ingesting or topically applying hyaluronic acid to improve skin's youthfulness and appearance, including reducing wrinkles, sagging, and pore size.
    • 1 Jul 2024 · recommends · YouTube ↗
      Explains that hyaluronic acid is a natural component of the skin that holds water, providing a plump and moist look characteristic of youthful skin, and mentions dermatologists suggest supplementation or topical application.
    • 6 Mar 2023 · Calcium · neutral · Podcast ↗
      Discusses "hard water" and the role of magnesium and calcium in cardiovascular health.
    • Date not recorded · Calcium · recommends · Website ↗
      Adequate intake of calcium is vital for bone health.

RAL Summary

Members OnlyTier 3 for Younger-Looking Skin for Women

Tier 3 fits: 95 reviews with 81% positive, and human studies give some support, mainly from eggshell membrane at a full dose and a pooled analysis of oral hyaluronic acid trials. The 15 of 17 hyaluronic acid count is inflated by injection and cream studies, but the tier still holds.

Where the evidence disagrees: 2 of the 36 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Skin

Combine with: Thorne Radiant Skin Complex is a skin-focused formula (typically combining ingredients such as collagen peptides, hyaluronic acid, vitamin C, antioxidants like astaxanthin or lutein, and skin-supporting nutrients), so it aligns well with goals for wrinkles, elasticity and hydration. Note that the ingredient list was not itemized, so exact doses are assumed from the product's positioning. To enhance results, consider stacking with additional vitamin C (500 to 1,000 mg daily) to support collagen synthesis, and omega-3 fatty acids (EPA/DHA, 1 to 2 g daily) to support the skin barrier and reduce inflammation. Ceramides or phytoceramides (30 to 350 mg) can improve moisture retention, while a broad-spectrum antioxidant such as astaxanthin (4 to 12 mg) or a vitamin E complex may help protect against UV-related oxidative damage. Zinc and biotin can support skin renewal and hair and nails. Pair with daily sunscreen, a topical retinoid, adequate water intake, and sleep, since these have the strongest evidence for visible anti-aging. Check with a clinician if pregnant, on meds, or taking medications before adding new supplements.

Possible side effects: No major side effects reported.

Supplement Facts

Calcium 52 mg · OVOLUX™† Eggshell Membrane 400 mg · eternalyoung®†† Botanical Blend 225 mg
Supplement Facts
Serving Size Two Capsules
Servings Per Container 30
Amount Per Serving% Daily Value
Calcium52 mg
Sodium10 mg
OVOLUX™† Eggshell Membrane400 mg†
eternalyoung®†† Botanical Blend225 mg†
Hyaluronic Acid120 mg†
† Daily Value not established.

Other ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Ascorbyl Palmitate.

Directions: Suggested Use: Take 2 capsules daily or as recommended by your health-care practitioner.

Barcode (UPC) 693749016007 · Label source: Reverseagelab · Report a label change

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Members OnlyThe highest ranked for the same goal

Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.