Advanced Trichology Collagen Gut Renewal Review

Advanced Trichology Collagen Gut Renewal is a powder supplement that you mix into a drink. One serving is 1 scoop (7.98 g), and each container holds 30 servings. Per serving the label lists Partially Hydrolyzed Guar Gum 3000 mg, Bovine Collagen Peptides 2500 mg, Magnesium 500 mg and Vitamin C 30 mg. It also shows 20 calories, 3 g total carbohydrate, 2.5 g dietary fiber and 2 g protein. The only other ingredient listed is maltodextrin. The directions printed on the label say to mix 1 scoop (7.98 g) into 8 to 12 oz of water or another beverage once daily. For a sensitive stomach, the label says to start with half a scoop for 7 to 14 days. Buyers who have commented say the powder did not dissolve for them and they could still taste it, and one planned to try it in a smoothie next time.

Product Focus: Digestion and Bloating
Tier ⓘ
Tier 4 · Rank 10
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 10 within Tier 4 for Digestion and Bloating; 44 of 56 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
41 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
75% of 2
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only65 human studies · 30 improved
65 human studies30 improved25 no effect362,121 people studied

The two main ingredients have the best support. Partially hydrolyzed guar gum is at a full dose when taken twice a day as directed. In 108 adults with irritable bowel syndrome, 6 grams a day for 12 weeks eased bloating and gas more than placebo, though other symptoms did not change [1]. In 188 adults it improved pain and bowel habits and was better tolerated than wheat bran [2]. In children it reduced bowel symptoms more than placebo [3]. One trial in constipated women using a mix with inulin found no benefit over placebo [4]. Magnesium is at a full dose, above the daily recommended limit, so members can take less. Magnesium-rich water relieved constipation in women [5] and made stools softer and more frequent in healthy adults [6]. Magnesium oxide helped constipated children [7], and a review found moderate evidence for magnesium salts in chronic constipation [8]. Collagen peptides are well below the studied dose of 20 grams. The only study was small, had no placebo and most participants did not finish [9]. Vitamin C has not been tested alone for gas, bloating or irregularity, and studies of people with irritable bowel syndrome found no link with symptoms [10]. Animal and cell studies are never counted.

See all 65 studies →Hide the studies

Review Totals and Summary

Members Only2 reviews · 75% positive
2 reviews · Advancedtrichology 2
75% positive0% neutral25% negative

Ratings across the stores that sell it total about 2, and the one written comment is about how the powder mixes, so the overall picture is thin. **Taste, smell and form:** The only theme in the feedback is how the powder behaves in a drink. The buyer says "It doesn’t desolve. I can still taste the powder." The same buyer plans to stir it into a smoothie next time instead. There is no feedback on what buyers say it did for them, on complaints beyond the mixing, on value for money, or on who it suits or did not suit, so those themes are left out.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Magnesium is the main ingredient, and most of the panel recommends or uses it, with seven recommending it, three using it, and one staying neutral. Sleep is the top reason, and several take 400 mg of the threonate form before bed, while others favor glycinate for its absorption, sleep, and muscle relaxation. Other reasons include muscle cramps, blood pressure, bone health, vitamin D function, recovery, and keeping electrolytes up, with daily amounts of 300 to 500 mg suggested as a minimum by two of them. A few pair it with electrolyte drinks or potassium, and one looks at it alongside protein, while one panelist said it does not fix waking during the night, and no one reported stopping it. Vitamin C is a smaller ingredient in this product, and the panel mostly links it to collagen support.

See all 10 biohackers →Hide the biohackers
  • Dr. Rhonda Patrick · Magnesium · recommends
    • 8 Nov 2026 · recommends · Instagram ↗
      Explains that magnesium helps the body activate and metabolize vitamin D, and that magnesium intake has been associated with lower odds of vitamin D deficiency and insufficiency.
    • 6 Nov 2026 · neutral · Instagram ↗
      Mentions that getting too little magnesium may play a role in declining testosterone levels.
    • 3 Nov 2026 · recommends · X ↗
      Recommends getting enough magnesium, around 300–400 mg daily from diet and supplements, as it is an essential cofactor for vitamin D metabolism. Magnesium glycinate is a good form.
    • 1 Nov 2026 · neutral · YouTube ↗
      Mentions magnesium as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 31 Oct 2026 · neutral · YouTube ↗
      Explains that magnesium helps control blood pressure by boosting the production of substances that relax blood vessels and improve cardiovascular health, citing a meta-analysis that found magnesium supplementation at an average dose of 368 mg per day notably lowers both systolic and diastolic blood pressure.
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
  • Dr. Eric Berg · Magnesium · recommends
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends Magnesium glycinate, noting its high absorption rate compared to magnesium oxide, and its support for energy, sleep, muscle relaxation, and vitamin D function.
    • 7 Nov 2026 · neutral · Instagram ↗
      Dr. Berg states that when nutrients like magnesium are too low, fatigue and weakness can follow.
    • 7 Nov 2026 · Vitamin C · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
    • 6 Nov 2026 · recommends · Podcast ↗
      Recommends focusing on magnesium to support stronger bones if a neck hump is associated with osteoporosis.
    • 6 Nov 2026 · neutral · Instagram ↗
      Explains that leg and calf cramps are most often caused by low magnesium, with leafy greens being a top source.
    • 6 Nov 2026 · recommends · YouTube ↗
      States that magnesium is a cofactor that allows B1 to work more efficiently.
    • 6 Nov 2026 · Vitamin C · neutral · Instagram ↗
      Mentions that bleeding or swollen gums point to vitamin C deficiency, and sugar competes with it directly, reducing absorption.
    • 4 Nov 2026 · recommends · YouTube ↗
      States that magnesium is the most important mineral for energy production, as one cannot make energy without it.
    • 1 Nov 2026 · neutral · YouTube ↗
      Magnesium is involved in 300 to 600 enzyme reactions, acts as a biological brake pedal, is the master controller over calcium, and is involved in making ATP, the energy currency of the body. It takes energy to go to sleep, and magnesium is required for relaxation and good sleep. Magnesium also helps balance cortisol levels and calm you.
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
  • Thomas DeLauer · Magnesium · recommends
    • 5 Nov 2026 · recommends · YouTube ↗
      Recommends taking magnesium glycinate and threonate at night to act as a brake on the nervous system, block excitatory signaling, help wind down, and support serotonin and melatonin production for better sleep.
    • 6 Nov 2026 · Vitamin C · recommends · YouTube ↗
      Recommends whole food vitamin C, found in kiwi fruit, citrus, and bell peppers, to help clear uric acid by competing at kidney transporters, preventing reabsorption.
    • 4 Nov 2026 · neutral · YouTube ↗
      Mentions that magnesium glycinate also helps a lot with sleep.
    • 2 Nov 2026 · neutral · YouTube ↗
      Mentions that restless leg syndrome is often treated with magnesium, but states that the sensation is actually coming from three other issues.
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
  • Andrew Huberman · Magnesium · recommends
    • 4 Nov 2026 · recommends · Instagram ↗
      Notes that Les Spellman's team includes 'Magnesium timed right' as part of their game plan to optimize recovery in unfavorable conditions.
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 13 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 6 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 22 Jun 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
    • 16 Jun 2025 · Vitamin C · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
  • Dr. Mark Hyman · Magnesium · recommends
    • 4 Nov 2026 · recommends · YouTube ↗
      Recommends magnesium breakthrough advanced ten from Biooptimizers, which is their most complete magnesium formula with 10 bioavailable forms and 550 milligrams of elemental magnesium, designed to support restful restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that a lack of magnesium can cause muscles and nerves to malfunction, resulting in muscle weakness, twitching, and cramps.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
  • Dave Asprey · Magnesium · uses
    • 3 Nov 2026 · uses · Instagram ↗
      Looks at magnesium alongside protein to keep muscle for the long run.
    • 3 Nov 2026 · recommends · YouTube ↗
      Suggests adding magnesium to help keep potassium in the system longer, as they work hand in hand.
    • 3 Nov 2026 · Vitamin C · neutral · YouTube ↗
      Recounts a doctor telling him in his 20s that vitamin C would kill him.
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 17 Aug 2026 · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 15 Aug 2026 · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 17 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 10 Aug 2026 · recommends · YouTube ↗
      Notes that magnesium is important for activating thiamine into its more biologically active form, and a magnesium deficiency can impair blood sugar regulation even with adequate thiamine intake.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • Date not recorded · Vitamin C · recommends · Website ↗
      Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
    • 20 May 2024 · uses · YouTube ↗
      Takes magnesium as a straightforward supplement.
    • 28 Feb 2024 · neutral · YouTube ↗
      Mentions that magnesium intake is often super low and impactful on testosterone levels.
    • 11 Dec 2023 · uses · Facebook ↗
      Discusses the important roles of magnesium in the body, how to determine if one might be deficient, the prevalence of magnesium deficiency, and its potential cognitive benefits.

RAL Summary

Members OnlyTier 4 for Digestion and Bloating

Controlled trials support partially hydrolyzed guar gum and magnesium for bloating and irregularity, but with only 12 reviews there is not yet enough buyer feedback to rank it higher than emerging.

Take 2 servings a day (2 scoops) to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 25 of the 65 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Digestive system

Combine with: Ginger is often paired with fiber blends like this because the two act on different parts of the gut, ginger on the stomach and fiber lower down. Probiotic strains such as Lactobacillus are often paired with fiber because the fiber serves as their food. L-glutamine is often paired with collagen peptides because both supply amino acids the gut lining uses. Zinc is often paired with glutamine because both feed into gut lining upkeep.

Possible side effects: High doses of magnesium can cause diarrhea and abdominal pain, and laxative studies noted bloating and cramping. The one buyer comment says the powder does not dissolve well and can be tasted.

Supplement Facts

Vitamin C 30 mg · Magnesium 500 mg · Partially Hydrolyzed Guar Gum 3000 mg
Supplement Facts
Serving Size 1 Scoop (7.98 g)
Servings Per Container 30
Amount Per Serving% Daily Value
Calories20
Total Carbohydrate3 g
Dietary Fiber2.5 g
Protein2 g
Vitamin C30 mg
Magnesium500 mg
Partially Hydrolyzed Guar Gum3,000 mg†
Bovine Collagen Peptides2,500 mg†
† Daily Value not established.

Other ingredients: Maltodextrin.

Directions: Mix 1 scoop (7.98g) into 8–12oz of water or beverage once daily. If you have a sensitive stomach, start with ½ scoop for 7–14 days.

Barcode (UPC) 199874385846 · Label source: Reverseagelab · Report a label change

Show entire label
The Advanced Trichology Collagen Gut Renewal label, 239g (8.43 oz)
Collagen Gut Renewal, 239g (8.43 oz)

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Our articles on this subject

Graded November 15, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.