Horbaach Berberine with Ceylon Cinnamon | Capsules Review

Horbaach presents Berberine with Ceylon Cinnamon in a 120 vegetarian capsule bottle. The page describes a scientifically designed formula that combines Berberine and Cinnamon, and it says the product features Ceylon Cinnamon and Berberine HCl, each in premium forms. The listed highlights state that the product is laboratory tested, that it contains no artificial flavour, and that it is free of gluten, wheat, preservatives and non-GMO ingredients. The product overview explains that Berberine is commonly extracted from the Barberry plant, while Ceylon Cinnamon, also called True Cinnamon, is described as the preferred variety of the spice. The page states that the formula combines Ceylon Cinnamon with Berberine hydrochloride from Barberry extract and that the capsules are non-GMO and gluten-free. The bottle images describe a 2000mg equivalent dosage with 120 vegetarian capsules. The product is marketed as free of gluten and wheat, soy, milk and lactose, and it is listed with a sale price of $20.39 and free shipping for continental US orders over $30. The warning states that the product is not intended for pregnant or nursing women or persons under 18, and advises consulting a doctor before use if taking medications or having a medical condition. It also notes that gastrointestinal discomfort may occur, and that the product should be stopped if adverse reactions occur. Users are told not to use the product if the seal under the cap is damaged or missing, to keep it out of reach of children, and to store it in a cool, dry place. The page lists quality badges including GMP, SOP, UL, USDA Organic and USP.

Product Focus: Blood SugarAlso covers:HormonesDigestionHeart
Tier ⓘ
Tier 2 · Rank 30
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 30 within Tier 2 for Blood Sugar; 30 of 48 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
88 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
99% of 2,291
Biohacker Mentions
9 of 10
Cost per month
$2173

Study, Trial or Testing Result Summary

Members Only90 human studies · 73 improved
90 human studies73 improved6 no effect18,621 people studied

This product gives 760 milligrams a day of a combined berberine and Ceylon cinnamon blend, but the label does not say how much of each is in it, so we cannot tell whether either reaches the doses used in studies. The berberine trials below used 1 gram a day, and the whole blend is less than that. Berberine has strong human evidence for blood sugar. Across 37 trials with 3,048 people with type 2 diabetes, it lowered fasting, after-meal and long-term blood sugar without raising the risk of low blood sugar [1]. A pooled look at 46 trials found similar drops plus better insulin resistance and cholesterol [2]. In 409 newly diagnosed adults, 12 weeks of berberine lowered long-term blood sugar more than placebo, with more stomach upset [3]. In 116 people, 1 gram a day for 3 months lowered long-term blood sugar from 7.5% to 6.6% [4]. Benefits seemed weaker after 90 days, above 2 grams a day and in people over 60 [5]. Ceylon cinnamon extract at 250 or 500 milligrams a day for four months lowered fasting and long-term blood sugar in 210 adults with type 2 diabetes [6]. A review of 45 cinnamon studies found about 62% showed a benefit, suggesting a modest effect [7]. Animal and cell studies are never counted.

See all 90 studies →Hide the studies

Review Totals and Summary

Members Only2,291 reviews · 99% positive
2,291 reviews · EBay 2,191 · Walmart 83 · Target 8 · Egypt Vitamins 2
99% positive0% neutral1% negative

Overall, Horbaach Berberine with Ceylon Cinnamon capsules get a mostly positive reception, with about 2,291 ratings across the stores that sell them. Most buyers are happy, though a few found little or no benefit. **What buyers say it did for them:** Most of the praise is about blood sugar. One buyer says, "it helps me keep my A1C below 6," and another reports morning readings "dropped to 100 and lower" after four months at three capsules a day. Some mention more energy within days or weeks, and one says it "took less than 3 days to work." Others take it for immune or heart support, and one new user is still waiting on a blood test to see what it does. A reviewer who tried it for two weeks says it "seems to help with digestion." **What they complain about:** Not everyone saw an effect. One buyer says the "Nature's a med" idea "didnt work for me," and another calls it "okay, not spectacular." One reviewer was sent the wrong item, potassium with iodine, by a retailer's fulfilment centre. That is an order mix-up rather than a fault in the capsules. A store summary also raises a labelling concern: the bottle lists 2,000mg of Ceylon Cinnamon but gives no amount of Berberine, even though Berberine comes first in the name. **Taste, smell, pill size and form:** The capsules are easy to take. One reviewer says they are "just as easy to swallow as others I've used," and another notes "No taste either!" A reviewer also likes that it combines two ingredients in one product. **Value for money:** Price gets favourable mentions. Reviewers say "Like the price" and "price is right on." Shipping is praised as quick, and one buyer calls it fast and free. A store summary backs this up, noting the fair price, quick delivery and free shipping. **Who it seems to suit and who it did not:** It seems to suit people who want a simple capsule to support blood sugar, and those who already know the ingredients. Several buyers are repeat users or have tried other brands. One says this is "by far the best I've tried." It suited others less, such as the buyer who expected a dramatic effect and saw none, and the one who found only mild digestive help. Some reviewers had used it only a few days and say it is too early to judge. Anyone who wants to know the exact Berberine dose may be put off by the label. Reviews of other forms of this product were left out; this summary covers the capsules only.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Most of the panel backs berberine, the main ingredient, mainly for blood sugar, with several also citing cholesterol, sleep, cravings and heart health. Doses are given as 500 mg taken with meals, one panelist cited 500 mg three times a day, and some prefer dihydroberberine or a bioavailable form. Cautions are common: one warned that taking it on an empty stomach can cause low blood sugar, headaches, dizziness and blurred vision, one advised care with other glucose lowering products, and one said he felt fine on up to 750 mg to a gram with a large carbohydrate rich meal. Two of them stopped taking it (one because it gave him headaches and carb cravings, the other when his diet changed), and a few stayed neutral or skeptical about the evidence or preferred a med. Cinnamon is the other main ingredient: several add it to coffee, oats, smoothies, pudding or a pinch in water for blood sugar and cravings, with one using half a teaspoon of Ceylon cinnamon, while one warned that it is high in oxalate.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Berberine · recommends
    • 30 Oct 2026 · recommends · YouTube ↗
      Recommends adding berberine as another natural remedy to the combination for cancer.
    • 25 Oct 2026 · recommends · Instagram ↗
      Dr. Eric Berg states that Berberine combined with a lower-carb diet may help support healthy blood sugar levels and reduce cravings over time.
    • 20 Oct 2026 · neutral · YouTube ↗
      Notes that some people add berberine, which supports healthy blood glucose and makes one insulin resistant.
    • 20 Sep 2026 · recommends · Facebook ↗
      Recommends taking berberine to block the effects of grains.
    • 20 Sep 2026 · Cinnamon · recommends · YouTube ↗
      Recommends adding a pinch of cinnamon to water daily, stating that it mimics insulin and activates insulin receptors, making cells more sensitive to insulin to help regulate blood sugar.
    • 20 Sep 2026 · Cinnamon · recommends · Facebook ↗
      Recommends consuming cinnamon to block the effects of grains.
    • 18 Sep 2026 · recommends · Instagram ↗
      Suggests incorporating anti-cancer foods like berberine to help prevent pancreatic cancer.
    • 10 Sep 2026 · Cinnamon · recommends · YouTube ↗
      Recommends taking a pinch of cinnamon with apple cider vinegar in a glass of water three times a day to stabilize blood sugar and reduce carbohydrate cravings.
    • 7 Sep 2026 · Cinnamon · neutral · Facebook ↗
      Cinnamon may be a more powerful combination with apple cider vinegar than you think, as both have been studied for their potential role in supporting healthy blood sugar levels.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends taking berberine, stating it is very beneficial for type 2 diabetes.
    • 3 Sep 2026 · neutral · X ↗
      Dr. Eric Berg states that berberine may support blood sugar, but it should not be treated as an equivalent substitute for other treatments.
    • 3 Sep 2026 · Cinnamon · neutral · X ↗
      Dr. Eric Berg states that cinnamon may support blood sugar, but it should not be treated as an equivalent substitute for other treatments.
    • 2 Sep 2026 · recommends · Facebook ↗
      Lists berberine as an epigenetic factor that may help with cancer prevention.
    • 23 Aug 2026 · recommends · YouTube ↗
      Recommends berberine as a natural version of a med, citing powerful research that shows it makes the body more sensitive to insulin and has fewer side effects than a med.
  • Dr. Mark Hyman · Cinnamon · recommends
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends adding cinnamon to coffee as a way to enjoy fall flavors without the high sugar content.
    • 21 Jul 2026 · uses · Instagram ↗
      Dr. Mark Hyman designed 'The World's Smartest Smoothie' using organic ingredients, including Organic Cinnamon.
    • 20 Jul 2026 · Berberine · uses · X ↗
      Takes 500 mg of Berberine with meals for blood sugar control.
    • 5 Jun 2026 · uses · YouTube ↗
      Adds a little bit of cinnamon to his overnight oats, noting that it helps blood sugar.
    • 11 Apr 2026 · uses · Facebook ↗
      Includes cinnamon in their smoothie to help with blood sugar balance.
    • 25 Sep 2024 · Berberine · recommends · YouTube ↗
      Recommends berberine to help with insulin resistance.
    • 26 Jul 2024 · Berberine · recommends · YouTube ↗
      Mentions that berberine may be helpful for people with insulin resistance and that he uses it in his practice.
    • 7 Jun 2024 · recommends · YouTube ↗
      Notes that herbs can be helpful for mobilizing toxins, specifically mentioning dandelion root, ginger, cardamon, and cinnamon.
    • 3 May 2024 · uses · YouTube ↗
      Mentions using cinnamon for blood sugar.
    • 17 Apr 2024 · recommends · YouTube ↗
      Recommends taking cinnamon as a natural way to increase GLP-1.
    • 17 Apr 2024 · Berberine · recommends · YouTube ↗
      Recommends taking berberine as a natural way to increase GLP-1.
    • 18 Mar 2024 · recommends · YouTube ↗
      States that cinnamon has been shown to help with insulin resistance and can be added to food or taken as a capsule.
    • 18 Mar 2024 · Berberine · recommends · YouTube ↗
      Used an herbal regimen that included berberine as part of a combination product to treat a patient's dysbiosis and yeast overgrowth.
    • 21 Feb 2024 · neutral · YouTube ↗
      Notes that cinnamon increases IL-10.
  • Thomas DeLauer · Berberine · neutral
    • 25 Oct 2026 · neutral · YouTube ↗
      Mentions dihydroberberine as a component that can be used to optimize and support the AMPK pathway, helping to tune it up and have a higher baseline.
    • 24 Oct 2026 · uses · YouTube ↗
      Has found berberine to be very helpful for some of his patients who are night snackers, especially those with a sweet tooth.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends berberine if one is going to have fruit later in the day, as it specifically restores the AMPK-driven fat suppression.
    • 26 Sep 2026 · recommends · YouTube ↗
      Recommends Dihydroberberine to improve mitochondrial performance and turn up the AMPK dial.
    • 1 Sep 2026 · recommends · Instagram ↗
      Recommends Berberine, stating that 500mg taken three times with meals has shown comparable results to a med in dropping HbA1c and fasting glucose.
    • 20 Aug 2026 · Cinnamon · recommends · Instagram ↗
      Recommends Ceylon cinnamon for pancreas health, describing it as an insulin mimetic that eases beta cell load.
    • 15 Aug 2026 · Cinnamon · recommends · YouTube ↗
      Recommends adding cinnamon to morning coffee to improve insulin sensitivity and stop insulin resistance from progressing.
    • 9 Aug 2026 · Cinnamon · recommends · YouTube ↗
      Recommends adding cinnamon to coffee, tea, or meals, stating that it contains a compound that mimics insulin in the body, allowing glucose to enter cells without needing a lot of food.
    • 8 Aug 2026 · Cinnamon · recommends · YouTube ↗
      Recommends adding a little bit of cinnamon to coffee, as it acts as an insulin mimetic, helping cells take up glucose more efficiently, keeping insulin low, extending the ghrelin window, and allowing for more fat burning.
    • 7 Aug 2026 · Cinnamon · recommends · YouTube ↗
      Recommends cinnamon for insulin resistance, explaining that it contains a polyphenol that mimics insulin and activates the insulin receptor directly, and also drives up AMPK.
    • 3 Aug 2026 · Cinnamon · recommends · YouTube ↗
      Recommends adding half to 1 teaspoon of cinnamon to water along with a meal, as its polyphenols enhance insulin receptor signaling, requiring less insulin for the same glucose load.
    • 28 Jun 2026 · Cinnamon · recommends · YouTube ↗
      Recommends consuming cinnamon in water 30 minutes before breaking a fast to help with metabolic transition, improve glucose tolerance, enhance glucose uptake, and reduce blood glucose response to carbohydrates.
    • 20 Jun 2026 · recommends · YouTube ↗
      Would start taking berberine because it helps with high glucose.
    • 20 Jun 2026 · Cinnamon · recommends · YouTube ↗
      Would use cinnamon whenever possible, as it acts as an insulin mimetic, helping glucose enter the bloodstream and reducing the need for insulin production, thereby increasing insulin sensitivity.
  • Siim Land · Berberine · recommends
    • 19 Oct 2026 · recommends · YouTube ↗
      Recommends berberine as a herbal supplement that increases fat metabolism, lowers mTor and blood sugar, making it a good combination for increased autophagy, and notes that meta-analyses show it reduces blood sugar, promotes weight loss, and decreases cholesterol.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Berberine for blood sugar and cholesterol, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Berberine as one of 15 supplements backed by human studies.
    • 28 Sep 2026 · warns · YouTube ↗
      Advises caution when using berberine with glycine, as it is a glucose-lowering medication.
    • 28 Aug 2026 · warns · YouTube ↗
      Is skeptical about most supplements, including berberine, because he doesn't see any evidence to back up their claims, which are often based on personal testimonials.
    • 7 Aug 2026 · neutral · YouTube ↗
      Mentions berberine as a compound that can increase autophagy, but notes it doesn't come close to exercise in effectiveness.
    • 4 Jul 2026 · Cinnamon · uses · YouTube ↗
      Includes cinnamon powder in their supplement stack.
    • 29 Jun 2026 · uses · X ↗
      He takes 500 mg of berberine with meals for blood sugar control.
    • 27 Jun 2026 · uses · YouTube ↗
      Would take berberine for pre-diabetes.
    • 12 Jun 2026 · warns · YouTube ↗
      Advises caution with berberine due to its antibacterial effects and potential to change the microbiome, especially if one doesn't have gut problems.
    • 6 Mar 2026 · neutral · YouTube ↗
      States that berberine also showed a lifespan extension in their hands.
    • 31 Oct 2025 · Cinnamon · warns · YouTube ↗
      Warns that cinnamon, a glucose disposal agent, is an MAO inhibitor and can make him feel 'revved up' or 'overly wired' due to his slow MAO gene.
    • 1 Apr 2024 · Cinnamon · uses · YouTube ↗
      Always has a cup of cinnamon ginger cardamom tea in the morning as a nice way to wake up.
    • 5 Dec 2023 · Cinnamon · recommends · YouTube ↗
      Mentions cinnamon as one of the glucose disposal agents that can help lower blood sugar response.
  • Dr. Rhonda Patrick · Berberine · neutral
    • 18 Oct 2026 · neutral · Instagram ↗
      Notes that berberine is a promising compound for cardiovascular health, with potential benefits spanning lipid metabolism, artery health, and the gut microbiome.
    • 18 Oct 2026 · neutral · X ↗
      Notes that berberine lowers LDL cholesterol in randomized trials and is interested in its connection to ApoB, artery plaque, and the gut microbiome.
    • 19 Aug 2026 · neutral · X ↗
      Notes that berberine has been on their radar for glucose control for years, and a new study on a biooptimized form of berberine showed reductions in fasting glucose, improved glucose tolerance, and an increase in fasting.
    • 1 May 2026 · recommends · Facebook ↗
      Recommends berberine for atherosclerosis, noting it has a more compelling evidence base, showing reduction in plaque formation and improvement in LDL, HbA1c, and glucose regulation.
    • 26 Aug 2025 · recommends · Facebook ↗
      Recommends Berberine for optimizing blood glucose, noting that meta-analyses show it reduces fasting glucose and HbA1c in people with type 2 diabetes.
    • 26 Aug 2025 · neutral · X ↗
      Notes that Berberine may not have the same inhibitory effect on muscular hypertrophy and strength gains as a med, but there are currently no studies to support or refute this.
    • 5 Aug 2025 · neutral · Podcast ↗
      Discusses ideal dosing for berberine.
    • 17 Jul 2025 · neutral · Facebook ↗
      Notes that berberine is also effective for blood glucose regulation, similar to apple cider vinegar.
    • 15 Jul 2025 · recommends · YouTube ↗
      States that berberine is undoubtedly effective for improving insulin sensitivity.
    • 27 Dec 2023 · neutral · YouTube ↗
      Discusses berberine, noting it is a mitochondrial toxin and an analog of a med, and mentions a systematic review suggesting it was beneficial in lowering LDL cholesterol and reducing a med myopathy.
  • Dave Asprey · Berberine · recommends
    • 1 Sep 2026 · recommends · YouTube ↗
      Recommends berberine as a good alternative to a med for longevity, citing its similar pathway effects without the downsides and its positive impact on the microbiome.
    • 29 Aug 2026 · neutral · YouTube ↗
      Dave Asprey discusses berberine as a plant compound that genuinely lowers blood glucose, comparable to a med in some trials, but notes its poor absorption and lack of lifespan data, classifying it as a glucose drug, not a longevity drug.
    • 4 Jun 2026 · recommends · Podcast ↗
      Notes that berberine supports sleep optimization, ketosis, and blocks a cancer growth pathway most drugs cannot touch.
    • 9 Apr 2026 · Cinnamon · warns · YouTube ↗
      Warns that cinnamon is high in oxalate.
    • 9 Oct 2025 · neutral · YouTube ↗
      Prefers a med over berberine, stating there is more data for a med, though berberine might be useful for diabetics.
    • 4 Sep 2025 · recommends · Podcast ↗
      Dave Asprey and his guests reveal how berberine can improve metabolism, regulate dopamine, and protect the brain, and can rival meds.
    • 4 Sep 2025 · neutral · YouTube ↗
      Mentions that GL Perfect contains bioavailable berberine, which is 250 times more bioavailable than normal.
    • 17 Jul 2025 · uses · YouTube ↗
      Takes berberine when he eats carbs to help manage blood sugar levels.
    • 6 Mar 2025 · neutral · YouTube ↗
      Notes that Intellx DNA provides information on what doses of berberine, such as two grams, were used in studies to improve blood sugars, emphasizing that a small amount won't have the same effect as a larger dose.
    • 3 Dec 2024 · uses · YouTube ↗
      Mentions needing 72 milligrams of Berberine as part of personalized supplements.
    • 22 Sep 2024 · warns · YouTube ↗
      States that berberine has anti-parasite qualities and he takes it nearly constantly, but warns that it is not without risk, as he experienced abnormally low heart rate and blood pressure on two occasions, which he attributes to berberine.
    • 11 Apr 2024 · Cinnamon · recommends · YouTube ↗
      Suggests trying cinnamon extract for controlling blood sugar.
    • 25 Sep 2020 · Cinnamon · uses · YouTube ↗
      Says he pounds cinnamon or cinnamon extracts when he eats sugar to blunt the insulin spike.
  • Andrew Huberman · Berberine · uses
    • 13 Jul 2026 · uses · X ↗
      Takes 500 mg of berberine with meals to help with blood glucose.
    • 2 Jul 2026 · stopped · YouTube ↗
      Dr. Huberman states he will skip berberine because it gives him brutal headaches, makes him crave carbohydrates, and drops his blood sugar.
    • 30 Apr 2026 · neutral · Podcast ↗
      Discusses berberine and other potent molecules for regulating blood glucose.
    • 30 Apr 2026 · warns · YouTube ↗
      Warns that berberine is a serious step and one should talk to their doctor about it, as taking it on an empty stomach can cause hypoglycemia, brutal headaches, dizziness, and impaired vision; however, when taken with a large, carbohydrate-rich meal, he felt fine on up to 750 mg or a gram.
    • 30 Apr 2026 · Cinnamon · recommends · Podcast ↗
      Recommends cinnamon as a tool to reduce blood sugar cravings.
    • 30 Apr 2026 · Cinnamon · warns · YouTube ↗
      Warns that cinnamon contains a med, which can be toxic at high levels, so one should not ingest more than about a teaspoon to a teaspoon and a half per day to avoid exceeding the problematic threshold.
    • 28 Aug 2025 · neutral · Podcast ↗
      Mentions the use of fasting-related supplements, including berberine.
    • 28 Aug 2025 · warns · YouTube ↗
      Huberman warns that if you take berberine without ingesting carbohydrates, many people, including himself, experience a splitting headache due to becoming hypoglycemic, as it is a glucose clearing agent.
    • 3 Apr 2025 · recommends · Podcast ↗
      States that berberine can further support fat loss and discusses its impact on insulin.
    • 3 Apr 2025 · neutral · YouTube ↗
      Mentions berberine as a compound, derived from a plant, that is in growing use for reducing blood glucose and is very potent at doing so.
    • 13 Nov 2023 · warns · YouTube ↗
      Warns that berberine can decrease testosterone levels, and that people often take it for blood sugar or longevity without considering this side effect.
    • 31 Oct 2023 · warns · YouTube ↗
      Huberman does not take berberine because it gives him brutal headaches, which he attributes to its effect of lowering blood glucose.
    • 21 Mar 2022 · Cinnamon · recommends · Podcast ↗
      Suggests cinnamon as a tool to reduce sugar cravings and spikes.
    • 21 Mar 2022 · Cinnamon · recommends · YouTube ↗
      States that cinnamon can adjust the rate of glucose entry into the bloodstream, possibly by slowing gastric emptying, and recommends sprinkling it on food or putting it in a beverage to blunt blood glucose increases, but warns about coumarin toxicity at high levels.
  • Ben Greenfield · Berberine · recommends
    • 13 Jun 2026 · recommends · YouTube ↗
      States that berberine is great for sleep, upregulating serotonin and dopamine, and that their bioavailable berberine product is taken by 75% of users for sleep, even though it was created for blood glucose management.
    • 23 May 2026 · Cinnamon · recommends · YouTube ↗
      Recommends cinnamon, noting it is a bark and not a seed, for use on the AIP diet.
    • 14 Mar 2026 · uses · TikTok ↗
      Now uses berberine as a natural strategy instead of a med and as a natural insulin-sensitizer.
    • 14 Mar 2026 · recommends · Podcast ↗
      Offers berberine as a natural alternative for better blood sugar control.
    • 14 Mar 2026 · recommends · YouTube ↗
      Recommends berberine or dihydroberberine as a powerful insulin sensitizing agent and a good alternative to a med, noting its comparable hemoglobin A1c reductions in some type 2 diabetes trials.
    • 14 Mar 2026 · Cinnamon · uses · TikTok ↗
      Now uses Ceylon cinnamon as a natural strategy instead of a med and as a natural insulin-sensitizer.
    • 14 Mar 2026 · Cinnamon · recommends · Podcast ↗
      Offers cinnamon as a natural alternative for better blood sugar control.
    • 14 Mar 2026 · Cinnamon · recommends · YouTube ↗
      Recommends Ceylon cinnamon at around 2g a day for modest fasting glucose improvements, suggesting its use in a morning smoothie, yogurt, or trail mix.
    • 26 Jan 2026 · neutral · Facebook ↗
      Berberine was mentioned in a study as a biofilm disruptor that can improve microbial access and affect outcomes in SIBO and methane-dominant cases.
    • 14 Dec 2025 · Cinnamon · recommends · Facebook ↗
      Recommends the Boundless Bar Cinnamon Roll flavor and provides a keto frosting recipe to pair with it.
    • 8 Nov 2025 · Cinnamon · uses · YouTube ↗
      He adds a little bit of cinnamon to his nightly protein smoothie.
    • 24 Oct 2025 · uses · Facebook ↗
      Uses Dihydroberberine as part of the Neuro Regenerate product to protect mitochondria, stabilize energy, and sustain cognitive output.
    • 6 Oct 2025 · Cinnamon · uses · Instagram ↗
      Ben Greenfield's Cinnamon Roll Boundless Bar contains ground cinnamon as an ingredient.
    • 18 Aug 2025 · recommends · Facebook ↗
      Recommends Dihydroberberine as a powerful antioxidant in Neuro Regenerate to support mitochondria and fuel clean, crash-free mental energy.
  • Peter Attia · Cinnamon · uses
    • 7 Dec 2025 · uses · YouTube ↗
      Uses cinnamon in his keto mousse in the evening.
    • 6 Jun 2024 · uses · YouTube ↗
      Puts a little bit of cinnamon on air-popped popcorn.
    • 11 Sep 2023 · Berberine · stopped · YouTube ↗
      Used to take berberine, which he called "poor man's a med," to buffer blood glucose and feel less sick after ingesting large amounts of calories on a cheat day, but stopped when he no longer followed the Slow Carb Diet.
    • 14 Feb 2020 · Berberine · uses · YouTube ↗
      Uses berberine in clinical practice as a weak inhibitor of the enzyme PCSK9, which can help a subset of patients who overexpress PCSK9 and have high LDL cholesterol.
    • 26 Jan 2020 · Berberine · recommends · YouTube ↗
      Suggests Thorne as the brand for berberine when recommending it to patients.
    • 23 Jan 2020 · Berberine · uses · YouTube ↗
      Uses berberine in clinical practice as a weak inhibitor of the enzyme PCSK9, which can help lower LDL cholesterol in a subset of people who overexpress PCSK9.
    • 29 Oct 2018 · Berberine · recommends · YouTube ↗
      Uses berberine in clinical practice because it is a weak inhibitor of the enzyme PCSK9, which degrades LDL receptors. He finds it effective for a subset of patients who overexpress PCSK9 and have high LDL, and he will prescribe it to see if it helps without prior testing.
    • 29 Oct 2018 · Berberine · neutral · Podcast ↗
      Shares insights about berberine.
    • Date not recorded · Berberine · stopped · Website ↗
      Used to take Berberine for longevity but stopped because he didn't see enough evidence.
  • Bryan Johnson · Cinnamon · uses
    • 23 Dec 2023 · uses · YouTube ↗
      Uses half a teaspoon of Ceylon cinnamon in his Nutty Pudding for blood sugar, liver, and pancreas health.
    • 27 Jul 2023 · uses · YouTube ↗
      Includes cinnamon in his Green Giant drink, which he consumes first thing in the morning.
    • Date not recorded · uses · Website ↗
      Bryan Johnson uses ½ tsp of ceylon cinnamon in his Nutty Pudding.

RAL Summary

Members OnlyTier 2 for Blood Sugar

Many large human trials and pooled analyses show berberine and Ceylon cinnamon lower blood sugar [1][6], and 99% of 2,291 reviews are positive, which meets tier 2. The exact amount of each ingredient is hidden in the blend.

Where the evidence disagrees: 6 of the 90 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Endocrine system, Digestive system, Cardiovascular system

Combine with: Berberine with Ceylon Cinnamon pairs well with other nutrients that support glucose metabolism and insulin sensitivity. Alpha-lipoic acid (R-ALA) and chromium picolinate or chromium polynicotinate can enhance insulin signaling and glucose uptake. Magnesium glycinate or citrate helps because low magnesium is linked to impaired insulin function. Alpha-lipoic acid, bitter melon, or gymnema sylvestre can add complementary support for post-meal glucose response. Omega-3 fish oil and soluble fiber such as psyllium or glucomannan help blunt glucose spikes and support healthy lipids. Take berberine with meals to limit GI upset. Consult a healthcare provider before combining it with meds, since additive glucose lowering may occur, and avoid it during pregnancy or when taking drugs metabolized by CYP enzymes without medical guidance.

Possible side effects: Berberine caused more stomach upset than placebo in trials; cinnamon had few side effects in studies. Reviews do not report major side effects.

Supplement Facts

Berberine Ceylon Cinnamon Complex 380 mg · Total Equivalent** 2000 mg · Berberine HCl 0
Supplement Facts
Serving Size 1 Vegetarian Capsule
Servings Per Container 120
Amount Per Serving% Daily Value
Berberine Ceylon Cinnamon Complex380 mg†
Total Equivalent**2,000 mg†
Berberine HCl (from Barberry Extract)0†
Ceylon Cinnamon 10:1 Extract (Cinnamomum verum) (bark)0†
† Daily Value not established.

Other ingredients: Vegetarian Capsule, Rice Powder, Vegetable Magnesium Stearate, Silica.

Directions: DIRECTIONS: For adults, take one (1) vegetarian capsule one to two times daily, preferably with meals.

Label source: Horbaach · Report a label change

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Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.