Montiff All- Basic 677 Milligrams Review
All-Basic 677 mg by Montiff is a dietary supplement providing a blend of 20 L-crystalline amino acids plus ornithine alpha-ketoglutarate (OKG) and the antioxidant alpha-lipoic acid, for everyday wellness. The product is listed on Blue Sky Vitamin as All-Basic 677 mg 200 caps by Montiff, with SKU MONT09044 and manufacturer's item number 10020. Each bottle contains 200 capsules, and the listed UPC is 683268100202. The page presents the product as a capsule supplement sold in a 200-count bottle. The product page highlights three points. First, it states that the formula provides a full spectrum of amino acids. Second, it says the product supports healthy muscles and tissues. Third, it notes that the formula provides antioxidant support. The page marks each of these claims with an asterisk, and it notes that the statements have not been evaluated by the Food and Drug Administration. Suggested use on the page is to take one to two capsules per day, a half-hour before meals, with water or fruit juice. The page advises not to take the capsules with hot fluids or dairy products, or to follow the instructions of a care professional. The page also advises consulting a healthcare provider before use, especially for people who are pregnant, nursing, taking medication, or have a medical condition. The ingredient list per 677 mg capsule includes alpha lipoic acid along with a long list of amino acids: L-Lysine HCL, L-Isoleucine, L-Glutamine, L-Tyrosine, L-Threonine, L-Alanine, L-Leucine, L-Histidine, L-Arginine HCL, L-Aspartic Acid, L-Valine, Ornithine alpha-Ketoglutarate, L-Methionine, L-Cystine, L-Glutamic Acid, Glycine, L-Phenylalanine, N-Acetyl L-Tyrosine, L-Serine, Taurine and L-Proline. Other ingredients are microcrystalline cellulose, magnesium stearate and gelatin. The page states that the product contains no starch, corn, milk, wheat, yeast, sugar, eggs, salt, artificial colors, binders, flavors, preservatives or fish derivatives. Pricing on the page shows an original price of $78.20 and a current price of $58.65, marked as a 25 percent saving. The item is listed as in stock and ready to be shipped. The page notes that most standard shipping orders arrive in one to four business days, and that orders placed before 3:00 pm CST on weekdays may ship the same day. Free shipping applies to orders over $30, and the page says shipping times are not guaranteed. The page also notes the product is not heat sensitive and carries no restrictions. No customer ratings or written reviews appear on this page, so no review statistics are available from it. The seller, Blue Sky Vitamin, lists email, Facebook, Instagram, Pinterest, X and YouTube contact channels.
Tier ⓘ
Tier 4 · Rank 1
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 1 within Tier 4 for Teeth; 2 of 4 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
35 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
– no stars shown, 5 reviews
Biohacker Mentions
10 of 10
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Study, Trial or Testing Result Summary
Members Only96 human studies · 59 improved
1 of these 96 human studies gave the ingredient by injection, not by mouth.
96 human studies59 improved22 no effect52,576 people studied
This is a blend of many amino acids plus alpha lipoic acid, and every amount is hidden in a 677 milligram blend, so no ingredient can be confirmed at a studied dose. Most tooth studies applied these ingredients in the mouth, not as a swallowed pill. Arginine toothpaste cut new cavities and eased tooth sensitivity in large trials [1][2][3], though some reviews rated the evidence weak [4][5]. A lysine mouthwash cleared a stomach bacterium from the mouth [6], and a lysine peptide mouthwash reduced plaque and bad breath [7]. A glutamine mouth rinse improved mouth hygiene in hospital patients [8]. Glycine results come from powder used in professional cleaning and were mixed [9][10]. A gel with leucine, proline, glycine and lysine was reported to speed gum healing after dental surgery, without a comparison group [11]. Taurine taken by mouth at 500 milligrams a day improved gum measures in 10 adults without a control group [12]. A multi-nutrient supplement with alpha lipoic acid helped gum treatment in two small trials [13][14]. Alpha-glucan oligosaccharide was studied only in rats [15]. Animal and cell studies are never counted.
See all 96 studies →Hide the studies
- Across ten trials with 15,546 people, arginine combined with fluoride (and a calcium compound) gave better protection against early crown and root cavities than fluoride alone or placebo, though the evidence was rated weak because of bias risks.Anti-Caries Effect of Arginine-Containing Formulations in vivo: A Systematic Review and Meta-Analysis.
- In a review of 30 studies with 10,136 people, toothpaste with 1.5% arginine plus fluoride was somewhat better at halting root cavities than regular fluoride toothpaste, but the evidence for this was rated very low.Systematic review on noninvasive treatment of root caries lesions.
- In four trials of topical drugs (including a med with arginine) applied during in-office tooth whitening, there was no reduction in tooth sensitivity compared with controls.Efficacy of topical drug application to manage in-office bleaching sensitivity: a systematic review and meta-analysis of…
- In a review of 74 trials with 5,366 people with sensitive teeth, arginine products significantly reduced tooth sensitivity over the long term, though not in the short term.Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis.
- A review of trials of arginine toothpaste found not enough reliable evidence that adding arginine prevents cavities, partly because of commercial conflicts of interest and problematic control groups.Arginine and Caries Prevention: A Systematic Review.
- In a review of 14 trials in baby teeth, an arginine-containing mint appeared to reduce cavity development, but the evidence was at high risk of bias.Effect of non-fluoride agents on the prevention of dental caries in primary dentition: A systematic review.
- A review of ten reviews, two of which covered arginine, found arginine toothpaste with a calcium base and fluoride to be promising for preventing early cavities, but more independent trials are needed.Calcium-Based Caries Preventive Agents: A Meta-evaluation of Systematic Reviews and Meta-analysis.
- A review of 33 studies on weak tooth enamel conditions found arginine pastes to be one of the effective treatments for teeth affected by molar-incisor hypomineralization.Dental hypomineralization treatment: A systematic review.
- In a review of nine trials of non-surgical treatment of implant gum disease, glycine powder air polishing reduced bleeding more than hand curette cleaning with chlorhexidine rinse.Non-surgical therapy for the management of peri-implantitis: a systematic review.
- Across five studies of people with gum disease around dental implants, glycine powder air polishing worked about as well as other cleaning at mild inflammation sites but reduced bleeding more at sites with bone-loss disease, though full healing was uncommon.Efficacy of air polishing for the non-surgical treatment of peri-implant diseases: a systematic review.
- In a review of 13 randomized trials of implant maintenance, glycine powder air-polishing improved gum measures more than traditional cleaning with hand curettes.Long-term Implant Maintenance: A Systematic Review of Home and Professional Care Strategies in Supportive Implant Therap…
- In 6,000 children aged 6-12 brushing twice daily for 2 years, toothpaste with 1.5% arginine, calcium and fluoride gave about 17-21% fewer new decayed, missing or filled teeth than fluoride-only toothpaste, though there was no difference after 1 year.Two-year caries clinical study of the efficacy of novel dentifrices containing 1.5% arginine, an insoluble calcium compo…
- In 6,000 Chinese children aged 10-14 using toothpaste for 2 years, 8% arginine toothpaste cut new cavities by about 25-26% versus fluoride toothpaste, while 1.5% arginine toothpaste performed about the same as fluoride.Arginine Dentifrices and Childhood Caries Prevention: A Randomized Clinical Trial.
- Over two years, nearly 3,706 Thai preschool children brushing with a 1.5% arginine fluoride toothpaste in schools had 13 to 34 percent fewer cavities than control schools, with up to 41 percent fewer in the most cooperative schools.School-based intervention for improving the oral health of children in southern Thailand.
- In 343 children aged 5-9, a daily lozenge with 2% arginine and probiotics for 10-12 months led to a smaller increase in tooth decay than placebo, with no effect on plaque or gum inflammation.The effect of a lozenge combining prebiotic arginine and probiotics on caries increment in children during 10-12 months,…
- In 300 patients after brain surgery, mouth care with a 5% glutamine solution lowered rates of oral debris, mouth sores, bad breath and dryness compared with saline care, and reduced the variety of mouth bacteria.Effectiveness of Glutamine Oral Care in Reducing Oral Mucositis and Improving Oral Health After Neurosurgery: A Randomiz…
- In 297 people with sensitive teeth, 8% arginine paste and toothpaste used for 24 weeks eased sensitivity significantly more than a fluoride-free control, with 273 completing the study.Efficacy of 8% arginine on dentin hypersensitivity: A multicenter clinical trial in 273 patients over 24 weeks.
- In 288 children aged 5 to 9 with low cavity risk, a daily lozenge containing 2% arginine and probiotics for 10 to 12 months, added to fluoride toothpaste, did not significantly reduce cavities compared with placebo, although the results trended in favor of the lozenge.The efficacy of combined arginine and probiotics as an add-on to 1450 ppm fluoride toothpaste to prevent and control den…
- In 277 people (159 with stomach pain, 118 without), a mouthwash with 0.4% lysine and 0.2% glycerol monolaurate cleared oral H. pylori bacteria in about 73% of those with oral infection, versus under 11% with standard stomach treatment, and raised stomach eradication success from about 61% to 82%.Oral Helicobacter pylori, its relationship to successful eradication of gastric H. pylori and saliva culture confirmatio…
- After 29 days of twice-daily brushing in 173 adults, a toothpaste with 1.5% L-arginine and zinc cut the bacteria in the mouth by 29 to 41 percent compared with a fluoride-only toothpaste.The Effects of Two New Dual Zinc plus Arginine Dentifrices in Reducing Oral Bacteria in Multiple Locations in the Mouth:…
- In 164 adults with tooth sensitivity, an arginine toothpaste significantly reduced sensitivity from baseline by week 8, though a casein phosphopeptide product gave the greatest reduction.Home-use agents in the treatment of dentin hypersensitivity: clinical effectiveness evaluation with different measuremen…
- In 147 adults with tooth sensitivity followed for 8 weeks, an 8% arginine toothpaste reduced sensitivity from week 2 onward compared with a negative control toothpaste, and performed similarly to a calcium sodium phosphosilicate toothpaste.An Exploratory Randomised Study to Evaluate the Efficacy of an Experimental Occlusion-based Dentifrice in the Relief of …
- In a 7-day study of 150 people with sensitive teeth, a toothpaste with 8% arginine reduced tooth sensitivity more than a standard fluoride toothpaste.Comparison of clinical efficacy of three toothpastes in reducing dentin hypersensitivity.
- In 150 patients with irreversible tooth pulpitis, a single pre-treatment dose of 1,155 mg a med-arginine, taken 30 minutes before numbing injection, raised the success of the numbing injection to 78% compared with 34% for placebo, though it did not differ from plain a med.Read the study on PubMed (38850383) →
- In 135 adults with tooth sensitivity, an 8% arginine toothpaste brushed twice daily for 11 weeks relieved sensitivity more than regular fluoride toothpaste, performing about the same as a 5% calcium sodium phosphosilicate toothpaste.Exploratory randomised controlled clinical study to evaluate the comparative efficacy of two occluding toothpastes - a 5…
- In 128 adults with tooth sensitivity, an arginine toothpaste gave the fastest relief one minute after use, comparable to strontium toothpaste, but a fluoride calcium phosphosilicate toothpaste performed best over six weeks.Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensi…
- In 105 people with dental implants followed for 12 months, all cleaning methods including glycine powder air polishing prevented gum inflammation, and the air polishing group showed a small increase in pocket depth.Comparison of different maintenance strategies within supportive implant therapy for prevention of peri-implant inflamma…
- Adults who brushed for six months with a toothpaste containing 1.5% arginine plus zinc and fluoride had significantly less plaque and gum inflammation than those using a regular fluoride toothpaste.A Clinical Investigation of a Dual Zinc plus Arginine Dentifrice in Reducing Established Dental Plaque and Gingivitis Ov…
- In 100 adults with gingivitis, a stannous fluoride toothpaste containing glycine gave 33.4% fewer bleeding sites and lower plaque than a control toothpaste after 12 weeks.Rapid Antigingivitis Efficacy of a Novel Stannous Fluoride Dentrifice: Results from a 12-Week Randomized Controlled Clin…
- In 96 people with early implant gum disease, glycine-based subgingival sandblasting reduced plaque, bleeding and inflammatory markers compared with controls, though erythritol worked better over the long term.Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration an…
- In 94 adults with gum inflammation, a toothpaste with 1.5% arginine and 0.96% zinc plus a mouthwash reduced gum inflammation and plaque more than fluoride toothpaste with placebo mouthwash over six months, though the difference faded once both groups used the same toothpaste.The effect of a multicomponent oral care regimen on gingival inflammation: A randomized controlled clinical trial.
- In 85 people with full-arch implant restorations, glycine powder air polishing reduced plaque around implants more than other cleaning methods, and about 80% of patients rated it highest for satisfaction.Efficacy of air-polishing devices without removal of implant-supported full-arch prostheses.
- In 83 adults followed for 12 weeks, a 1.5% arginine toothpaste increased plaque pH and arginine breakdown by bacteria, but it did not significantly change how many cavities became inactive compared with a fluoride toothpaste.Metabolic Profile of Supragingival Plaque Exposed to Arginine and Fluoride.
- In 81 adults with sensitive teeth, a stannous fluoride toothpaste gave greater relief than an 8% arginine toothpaste over three days, so the arginine toothpaste performed worse as the comparison product.Rapid desensitizing efficacy of a stannous-containing sodium fluoride dentifrice.
- In 80 adults with tooth sensitivity, an arginine and calcium carbonate toothpaste reduced pain right after one application and after three days of twice-daily brushing, with relief similar to a strontium toothpaste.A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, fo…
- In a 75-person trial, sensitivity fell in all groups, but an 8% arginine toothpaste did not clearly beat placebo and was less effective than a 5% fluorocalcium phosphosilicate toothpaste.A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpa…
- In 75 adults with gum disease, L-arginine added to professional cleaning significantly reduced deep gum pockets compared with cleaning alone after one year, though L-ornithine gave greater benefits.L-ornithine supplementation in periodontitis treatment yields greater benefits than L-arginine after one year: Part II o…
- In 74 people with gum disease undergoing periodontal treatment, 8% arginine and calcium carbonate paste and toothpaste prevented root sensitivity from developing and kept it lower for 17 weeks compared with fluoride products.Control of dentin/root sensitivity during non-surgical and surgical periodontal treatment.
- In 72 orthodontic patients, brushing with an 8% arginine toothpaste twice daily for 30 days significantly lowered Streptococcus mutans bacteria around braces, while regular fluoride toothpaste did not.Effect of 8% arginine toothpaste on Streptococcus mutans in patients undergoing fixed orthodontic treatment: randomized …
- In 62 adults having teeth whitened, a gel with a med and arginine applied beforehand made tooth sensitivity less likely and less intense than a placebo gel, without reducing whitening.Read the study on PubMed (38309571) →
- In 62 adults, a med-arginine gel applied before in-office tooth bleaching did not change whitening outcomes compared with placebo gel after 4.5 years, and the whitening showed mild rebound.In-office Bleaching After a Desensitizing Protocol: a 4.5-Year Follow-up of a Randomized Controlled Trial.
- In 60 adults with tooth sensitivity, an 8% arginine toothpaste reduced sensitivity at five minutes, one week and four weeks, but it worked about as well as a nano-hydroxyapatite toothpaste.Comparative Evaluation of Effect of Nano-hydroxyapatite and 8% Arginine Containing Toothpastes in Managing Dentin Hypers…
- In 60 people with severe gum disease, 5 seconds of glycine powder air polishing per tooth surface removed most of the plaque film below the gumline in pockets up to 3 mm deep, while untreated teeth stayed stained.Subgingival debridement efficacy of glycine powder air polishing.
- In 60 people with gum pockets treated for one month, adding glycine powder air-polishing to scaling and root planing gave no extra benefit for gum measures or bad breath.Efficacy of glycine powder air-polishing combined with scaling and root planing in the treatment of periodontitis and ha…
- In 59 people with gum inflammation around dental implants, all implants got glycine powder air polishing after cleaning; adding chlorhexidine gel gave no lasting extra benefit over cleaning alone up to 6 months, so this study does not test glycine itself.Efficacy of Xanthan-Based Chlorhexidine Gel in Peri-Implant Mucositis Treatment: A Split-Mouth Randomized Clinical Trial…
- In 52 people with gum inflammation around dental implants, adding glycine powder air polishing to ultrasonic cleaning did not help more than cleaning alone over 12 months; full resolution was reached in 16% of the glycine group and 27% of the control group.Treatment of peri-implant mucositis: Adjunctive effect of glycine powder air polishing to professional mechanical biofil…
- In 50 adults with sensitive teeth, one professional application of an 8% arginine and calcium carbonate paste reduced air-blast sensitivity by 44.7 percent, which was 24.4 percent more than a control paste.Beneficial effects of an arginine-calcium carbonate desensitizing paste for treatment of dentin hypersensitivity.
- In 50 people with deep gum pockets, glycine powder air polishing was safe, less painful and faster than scaling and root planing, but it reduced bleeding less and was not better at lowering harmful bacteria after 7 days.Subgingival plaque removal using a new air-polishing device.
- In a randomized trial of 47 people with gum-around-implant disease, glycine air-polishing gave better results than plastic curettes at 6 months, though overall treatment success stayed low.Clinical Evaluation of Three Surgical Modalities in the Treatment of Peri-Implantitis: A Randomized Controlled Clinical …
- In 46 people with dental implants, glycine powder air abrasion maintenance improved peri-implant gum health over 6 months and worked better than manual cleaning with chlorhexidine for probing depth and plaque.Air-abrasive debridement with glycine powder versus manual debridement and chlorhexidine administration for the maintena…
- In 45 patients with tooth sensitivity, an 8% arginine and calcium carbonate toothpaste significantly reduced pain over 90 days, with results similar to a peptide gel.Self-assembling peptide matrix for treatment of dentin hypersensitivity: A randomized controlled clinical trial.
- In 45 people with gum disease after non-surgical treatment, an 8% arginine toothpaste reduced tooth sensitivity through week 2 of twice-daily brushing, compared with a control toothpaste.Bioactive glass and arginine dentifrices immediately relieved dentine hypersensitivity following non-surgical periodonta…
- In 42 adults with advanced gum disease, a multinutrient supplement containing alpha-lipoic acid taken for 2 months alongside gum treatment reduced pocket depth (0.75 mm vs 0.51 mm) and gum bleeding (21.9% vs 12.5%) more than placebo, while other measures did not differ significantly.Effect of a multinutrient supplement as an adjunct to nonsurgical treatment of periodontitis: A randomized placebo-contr…
- In 41 people with gum disease, adding glycine powder air-polishing to deep cleaning gave similar gum and bacterial results to deep cleaning alone over 3 months, though blood inflammation markers fell after both treatments.Clinical, inflammatory and microbiological outcomes of full-mouth scaling with adjunctive glycine powder air-polishing: …
- In 40 children with asthma or allergic rhinitis, two remineralising toothpastes used twice daily after a glycine powder cleaning significantly reduced tooth sensitivity and gum indices over 6 months; glycine itself was not separately tested.Evaluation of two different remineralising toothpastes in children with drug-controlled asthma and allergic rhinitis: a …
- In 39 adults with advanced gum disease who finished the trial, a multi-nutrient supplement containing alpha-lipoic acid taken twice daily for 8 weeks alongside gum treatment gave a larger reduction in pocket depth and bleeding than placebo, though the pocket depth difference was reported as not statistically significant in this summary.Multi-nutrients and periodontal disease - a new adjunct to improving treatment outcomes? A randomised placebo-control cl…
- In 37 people with inflamed gums around one implant, glycine powder air-polishing treatment reduced plaque, bleeding and deep pockets over 12 months compared with baseline, as did ultrasonic cleaning.Treatment of peri-implant mucositis using a glycine powder air-polishing or ultrasonic device: a randomized clinical tri…
- In 34 adults with intellectual disability, a daily arginine varnish for eight weeks reduced Streptococcus mutans bacteria, but plaque scores improved most with chlorhexidine varnish and gum inflammation did not differ between groups.Clinical and microbiological effects of chlorhexidine and arginine sustained-release varnishes in the mentally retarded.
- In 33 healthy adults, 65 micrometer glycine powder air polishing after scaling cleaned teeth about as well as the baking soda method and left less surface staining at 1, 3 and 6 months over 6 months.[Investigation of the clinical effect of 65 μm glycine powder air-polishing(GPAP) after ultrasonic scaling during subgin…
- In a 10-day study of 31 people, a 1.5% arginine toothpaste lost much more tooth enamel to acid than a 0.454% stannous fluoride toothpaste.Erosion protection efficacy of a 0.454% stannous fluoride dentifrice versus an arginine-containing dentifrice.
- In 31 patients with peri-implantitis followed for 6 months, glycine air polishing worked no differently than implantoplasty surgery for reducing bleeding, pocket depth and bone loss.Implantoplasty Versus Glycine Air Abrasion for the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial.
- In 30 people with implant-supported full-arch dentures, glycine air polishing removed more plaque than manual scaling and was as effective as sodium bicarbonate air polishing, with higher comfort scores than sodium bicarbonate.Comparison of biofilm removal using glycine air polishing versus sodium bicarbonate air polishing or hand instrumentatio…
- In 30 people with peri-implant mucositis, glycine powder air-abrasive cleaning reduced bleeding and gum pocket depth from 1 week to 3 months, more than ultrasonic cleaning, and lowered inflammatory signals while shifting the mouth bacteria toward a healthier mix.Impact of Glycine Powder Air-Abrasive Debridement on Peri-Implant Mucositis: A Randomized Control Trial of Clinical, Mic…
- In 28 adults with sensitive teeth, an 8% arginine paste plus toothpaste reduced sensitivity as well as other treatments at one month, and its effect grew over three months, though differences among treatments were not statistically significant.Treatment of Dentin Hypersensitivity Using Nano-Hydroxyapatite Pastes: A Randomized Three-Month Clinical Trial.
- In 28 patients with gum disease around implants, adding glycine powder air polishing to scraping reduced bleeding and pus more than scraping alone over 8 weeks, mainly in implants with mild gum inflammation.[Efficacy of combined application of glycine powder air-polishing in non-surgical treatment of peri-implant diseases].
- In 27 people with chronic gum disease, adding glycine powder air-polishing to deep cleaning reduced gum fluid volume more than deep cleaning with water rinsing at 3 months, with no clear difference in inflammatory markers by 6 months.Subgingival glycine powder air-polishing as an additional approach to nonsurgical periodontal therapy in subjects with u…
- In 26 people with early gum-around-implant disease, glycine powder air abrasion added to cleaning improved probing depth, bleeding and plaque over 6 months, but it was not clearly better than cleaning alone or with chlorhexidine or ozone.Efficacy of different nonsurgical treatments for peri-implantitis: a multi-arm randomized controlled clinical trial.
- In 25 people in supportive periodontal care, glycine powder air-polishing used alone left deeper gum pockets than hand scaling or ultrasonic scaling at 1, 3 and 6 months and was not superior to them.Pilot study on the clinical and microbiological effect of subgingival glycine powder air polishing using a cannula-like …
- In 25 people with moderate to mild gum-around-implant disease, subgingival glycine air polishing improved gum health measures more than conventional scaling at 6 months, though the benefit may be short-term.[Efficacy of subgingival glycine air polishing on the treatment of moderate-mild peri-implantitis].
- In 23 people in maintenance care, glycine powder air polishing worked as well as ultrasonic scaling over 12 weeks, was more comfortable, and took less time.[Clinical observation of glycine powder air-polishing during periodontal maintenance phase].
- In 22 people with chronic gum disease in maintenance care, glycine powder air-polishing improved plaque and gum scores and caused less gum tissue damage than sodium bicarbonate air-polishing or ultrasonic scaling.Efficacy of glycine powder air polishing in comparison with sodium bicarbonate air polishing and ultrasonic scaling - a …
- In a randomized trial of 22 people with early gum disease around implants, glycine air polishing and ultrasonic scaling with chlorhexidine rinse gave similar results at 2 months, though only the glycine group showed a significant drop in bleeding.[Efficacy of subgingival glycine air polishing on patients with early peri-implant diseases].
- Over 90 days in 21 people with sensitive teeth, an 8% arginine-calcium carbonate paste reduced pain by 65.4 percent, while untreated teeth got more sensitive.Comparison of low level laser and arginine-calcium carbonate alone or combination in the treatment of dentin hypersensit…
- In 21 adults with gum disease in maintenance care, 65 μm glycine powder air-polishing over 12 weeks gave similar clinical results to ultrasonic scaling and polishing paste, with no significant difference in the types of mouth bacteria found, though bleeding was reduced only with the ultrasonic method.[Preliminary study of subgingival microorganism changes after glycine powder air-polishing treatment during periodontal …
- In 16 patients with tooth sensitivity, a paste with 8% arginine, calcium carbonate and potassium nitrate reduced sensitivity over time, but it did not clearly beat a placebo paste on sensitivity, though it sealed dentine tubules better in lab tests.Evaluation and comparison of the effects of a new paste containing 8% L-Arginine and CaCO3 plus KNO3 on dentinal tubules…
- In a 4-week mouth-rinse study of 14 people with artificial enamel lesions, a 2% arginine bicarbonate rinse five times daily did not produce significantly more remineralization than water.Effects of rinsing with arginine bicarbonate and urea solutions on initial enamel lesions in situ.
- In 13 adults with periodontitis, a mouthwash containing hyaluronic acid, hydrogen peroxide and glycine used twice daily for 7 days shifted the mouth bacteria and fungi toward a healthier profile, with lower levels of a yeast-type fungus.Cross-kingdom dynamics of the subgingival bacteriome and mycobiome: A pilot study on the effects of a novel HA-H₂O₂-Glyc…
- In 12 people wearing plaque devices for 6 weeks, an 8% arginine toothpaste significantly reduced acid production by plaque bacteria without changing plaque metabolic activity, live-to-dead bacteria ratio, or total biofilm mass.Effect of toothpaste containing arginine on dental plaque-A randomized controlled in situ study.
- In 12 adults, an arginine fluoride toothpaste protected enamel from decay in a lab-style mouth-device test about as well as a regular fluoride toothpaste, though it lowered sticky bacterial film.In situ Effect of Arginine-Containing Dentifrice on Plaque Composition and on Enamel Demineralization under Distinct Car…
- In an 8-week in situ study of 12 people, a fluoride toothpaste with 1.5% arginine and calcium carbonate reduced root caries-like lesion area more than a standard fluoride toothpaste, though less than high-fluoride toothpastes.Root caries lesions inhibition and repair using commercial high-fluoride toothpastes with or without tri-calcium phospha…
- In 10 adults with cavity-prone mouths, arginine rinsing reduced the acid drop in plaque after sugar and reduced the sticky carbohydrate matrix of the plaque compared with placebo.Arginine modulates the pH, microbial composition, and matrix architecture of biofilms from caries-active patients.
- In 10 people with deep gum pockets, glycine powder air-polishing caused less damage to the gum lining than sodium bicarbonate air-polishing or hand instruments, with the gum tissue intact after 14 days.Effect of glycine powder air-polishing on the gingiva.
- In a small study of 6 people wearing dental splints with implant samples, glycine powder airflow combined with taurolidine removed the most plaque from implant surfaces and was quicker than plastic curettes.Taurolidine as an effective and biocompatible additive for plaque-removing techniques on implant surfaces.
- In a randomized, double-blind trial, a mouthwash containing a poly-lysine peptide blend and domiphen cut bad breath gas levels and plaque more than the control mouthwash over 7 days, and it was found to be safe.Efficacy of a mouthwash containing ε-poly-L-lysine, funme peptides and domiphen in reducing halitosis and supragingival …
- In lab and 10-day mouth tests, an arginine and sodium monofluorophosphate toothpaste protected tooth enamel from acid erosion less well than a stabilized stannous fluoride toothpaste.Erosion protection benefits of stabilized SnF2 dentifrice versus an arginine-sodium monofluorophosphate dentifrice: resu…
- In 56 patients having a tooth pulled under acupuncture, the 18 who took 4 grams of D-phenylalanine 30 minutes beforehand had a 35% greater rate of excellent or good pain relief than the 38 on placebo (14 of 18 rated excellent or good).Studies on the enhanced effect of acupuncture analgesia and acupuncture anesthesia by D-phenylalanine (2nd report)--sche…
- In a split-mouth study of 15 people with full-arch implant restorations, glycine air polishing reduced plaque more than saline cotton-pellet cleaning at 3 months, but it did not reduce harmful bacteria more than the control.Antimicrobial Activity of Glycine Air Polishing: A Clinical Split- Mouth Study on Full-Arch Implant-Supported Rehabilita…
- In a small split-mouth pilot of 8 adults, a single application of an 8% arginine toothpaste reduced cervical tooth sensitivity by 30 days compared with baseline, though it was not better than the other toothpastes tested.Effectiveness of Three Desensitizing Dentifrices on Cervical Dentin Hypersensitivity: A Pilot Clinical Trial.
- In 10 adults with chronic gum disease, taking 500 mg of taurine once daily for 15 days was followed by significant reductions in blood and gum tissue markers of cell damage from oxidative stress, and significant improvement in gum health measures, though there was no control group.Evaluation of the efficacy of taurine as an antioxidant in the management of patients with chronic periodontitis.
- In a retrospective study of 527 people in periodontal maintenance over a median of about 5 years, adding glycine powder air polishing below the gumline did not improve results compared with mechanical cleaning alone, and furcation (tooth root area) status showed a trend toward worsening.Retrospective analysis of the long-term effect of subgingival air polishing in supportive periodontal therapy.
- In 30 people with early gum inflammation around implants, adding glycine powder air-polishing to professional cleaning reduced pocket depth more than professional cleaning alone over 6 months.Adjunctive glycine powder air-polishing for the treatment of peri-implant mucositis: an observational clinical trial.
- In a lab study of dental plaque from 29 children, plaque from children with severe early tooth decay used less phenylalanine than plaque from children without cavities, which may mean phenylalanine could slow decay; no one was given phenylalanine as a supplement.Carbon source utilization patterns in dental plaque and microbial responses to sucrose, lactose, and phenylalanine consu…
- In a case series of 9 people with 14 implants with mild gum-around-implant disease, glycine air-polishing followed by platelet-rich fibrin irrigation improved probing depth and attachment levels and gained bone over 6 months, though no implant was considered fully treated and there was no control group.A prospective evaluation of subgingival irrigation with i-PRF following non-surgical treatment of peri-implantitis.
- In three volunteers, alanine was more abundant in mature dental plaque biofilms than in newly formed biofilms, and caries lesions progressed or arrested with shifts in bacterial populations; no alanine supplement was given, so this does not show that alanine improves tooth health.The bacterial microbiome and metabolome in caries progression and arrest.
- A gel containing leucine with three other amino acids and hyaluronate sped healing of gum tissue after tooth extraction, laser surgery and dental implant placement, with no post-operative infections reported, though the abstract gives no participant numbers or control group.Accelerated wound healing of oral soft tissues and angiogenic effect induced by a pool of aminoacids combined to sodium …
- In an animal study of six dogs, a chitosan film with taurine placed in tooth-bone defects showed more cell changes and faster early healing than chitosan film alone at day 7, but this was not tested in people.Chitosan film enriched with an antioxidant agent, taurine, in fenestration defects.
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Customer feedback is sparse. Across the retailer sites I checked, I found only about four distinct reviews, and they are mostly old (2011–2015). Some other retailers show no reviews at all. The themes are consistent but should be read with that small sample in mind. Long-term users are the most positive. One reviewer says they have used these amino acids for years and calls them the best quality they have found. Another calls it the most complete amino acid product they have used. This suggests people value the breadth of the 20-amino-acid profile and the perceived quality. A third buyer simply says the 500-capsule bottle works well and that they noticed a difference from their previous routine. That comment is vague about what changed. The most specific feedback is about cosmetic benefits. One user took three capsules in the morning and three before bed. She says results took a long time, about 6–8 months. After that her nails grew in stronger and smoother, and she thinks the wait was worthwhile. So the theme is real but slow benefit, which fits the proline and collagen-related claims. Patience seems to be part of the experience. One reviewer says a plastic surgeon recommended the product to make up for amino acids missing from their diet. That points to use in recovery or nutritional-support settings, in line with the manufacturer's positioning. I found no complaints in the sources I checked. There was nothing about capsule size, taste, digestive upset or price, and no negative reviews. The absence of criticism mostly reflects how few reviews exist. It is not strong evidence that the product is trouble-free. Buyers who want to know about side effects, capsule size or value will not find that information in the reviews. They should rely on the label and on advice from a healthcare provider.
Biohacker Summary
Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it
This product is an amino acid blend, and every ingredient in it is a smaller ingredient, so the panel has no single main ingredient to rank. Glycine drew the most attention: most of the panel recommends or uses it, mainly for sleep, with 2 grams before bed the common dose, while one panelist takes 10 grams a day for blood sugar and another pairs it with NAC for antioxidant support. Leucine is backed by several panelists for muscle building, with doses of 2 to 4 grams per meal or 8 to 9 grams a day, and taurine gets mostly positive or neutral views, with one noting the human evidence is still thin. Tyrosine is used by two panelists for focus, at 500 to 1,000 milligrams early in the day, often with alpha GPC and coffee, though one statement records that panelist as having stopped. Glutamine is taken or recommended for gut repair and immune support, and lysine and threonine each got only a passing mention from one panelist.
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Siim Land · Glycine · recommends
- Suggests that a higher glycine to methionine ratio appears to preferentially target visceral fat and improve insulin sensitivity.
- Recommends pairing NAC with glycine to support antioxidant activity in your sleep.
- Believes glycine is the best longevity supplement and encourages viewers to learn more about its longevity benefits.
- States that Glycine can be a useful addition for some people for sleep.
- Increased his glycine supplementation to 10g a day, noting that it balances methionine and improves blood sugar and glycation.
- Personally uses glycine for its health benefits, including glutathione, blood sugar glycation, and potentially sleep, and notes that it appears to have some autophagy benefits by increasing autophagy through its role in methionine metabolism.
- Recommends keeping methionine intake slightly lower to support autophagy.
- Notes that glycine is one of the most important building blocks for collagen synthesis, making up 30% of collagen, and that 12g of glycine a day is needed for collagen turnover.
- Increased his glycine intake as part of an experimental amino acid strategy.
- Retweeted a study stating that 3 g of glycine before bed helped people fall asleep faster and reach deep sleep sooner.
- Lowered his methionine intake as part of an amino acid strategy.
- Takes around 3 to 5 grams of glycine before bed, often mixed with chamomile tea, as human trials have found it can improve subjective sleep quality and shorten the time to fall asleep and enter deep sleep.
- States that taurine supports normal muscle, nerve, and heart function, and supplement trials suggest benefits for some metabolic markers, exercise performance and blood pressure.
- Recommends Taurine for blood pressure and metabolic health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
Ben Greenfield · Leucine · recommends
- Describes leucine as the 'ignition' that turns on the signal for muscle protein synthesis, and that a sufficient dose is needed to hit the dose response and then have other essential amino acids to maintain the signal.
- Taurine on its own isn’t particularly impressive as an ergogenic aid, but when combined with caffeine, there are significant increases in power production.
- States that leucine is the primary trigger for muscle protein synthesis and recommends an essential amino acid blend with about 40% leucine for maximum stimulation.
- Mentions Dr. James Di Nicolantonio's claim that glycine, at 5 to 6 grams, can help protect cell membranes against damage from oxidized oils, citing rodent studies.
- Recommends taurine supplementation, especially for plant-based dieters, citing a 2023 study showing its decline with age and its potential to extend health span and restore markers of brain aging in mice, with anecdotal evidence for human brain function.
- Recommends pulsing with compounds like leucine for maintaining and building muscle and maximizing muscle protein synthesis.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- He takes 2 grams of Glycine before bed for sleep.
- A new study found that lowering methionine in the diet of mice significantly increased calorie burning and weight loss, matching the metabolic effects of cold exposure.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- He takes 2 grams of Glycine before bed for sleep.
- He takes 2 grams of Glycine before bed for sleep.
Thomas DeLauer · Glycine · neutral
- Explains that glycine is critical for collagen synthesis, which supports the intestinal wall, and deficiency can slow down the repair process.
- States that glutamine is the primary fuel source for intestinal cells, and its availability is crucial for the integrity of the gut barrier.
- Explains that the body needs roughly 10g more of glycine per day than a typical modern diet provides, and that this deficit can lead to issues with creatine production, connective tissue repair, and sleep. He recommends increasing glycine intake.
- Recommends taurine, stating it raises the stress threshold, acts as a GABA and glycine receptor modulator, and protects neurons from stress, ultimately lowering cortisol release.
- Identifies leucine as the primary trigger for the mtorc1 pathway, which is the master switch for muscle protein synthesis, and recommends 2 to 3 grams per meal for those under 40, and 3 to 4 grams for those over 40.
- Recommends supplementing with glutamine for a calming effect, especially when experiencing high stress, injury, illness, or increased training volume, as it acts as a precursor to GABA and helps the body produce more of it.
- Shifts towards glycine when cutting to keep their nervous system calm through the deficit.
- Loads up on extra glutamine during muscle building phases.
- Explains that glycine is a critical amino acid for glutathione production, and the body often has a significant shortage of it, with creatine synthesis consuming a large amount of available glycine.
- Recommends glycine, either from supplements or food sources like bone broth, collagen peptides, and chicken skin, to help build up glutathione.
- Recommends taking 2 to 3 grams of glycine tonight to help fall asleep.
- Recommends glutamine as one of the things that support the gut lining.
- Explains that leucine is important for muscle, with beef, whey, milk, and sardines clearing the 2-3g leucine threshold per meal, and that the threshold increases with age.
- States that leucine is what flips the switch for muscle protein synthesis, and that adding leucine and essential amino acids to a small dose of whey can match the effect of a full 25-gram dose of protein.
Andrew Huberman · Tyrosine · neutral
- Mentions Tyrosine as a precursor to dopamine.
- Discusses L-Tyrosine as a neuromodulator for cognitive enhancement and focus.
- He recommends 500 mg to 1,000 mg of L-tyrosine, an amino acid precursor to dopamine, taken alone or in conjunction with alpha GPC, to increase focus without stimulant-based alertness.
- Uses 500 milligrams of L-Tyrosine in capsule form, often combined with Alpha-GPC and coffee, early in the day before workouts or concentrated mental work to increase dopamine transmission for concentration and focus.
- Discusses L-Tyrosine and its relation to dopamine, also mentioning combining tools.
- Takes 2 grams of Glycine before bed for sleep.
- Discusses L-Tyrosine as a supplement that can increase dopamine.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 500 mg of L-Tyrosine in the morning for focus.
- Takes 2 grams of Double Wood Glycine before bed for sleep.
- He takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Suggests that adding free leucine, perhaps one gram in a capsule with a normal meal, can significantly boost protein synthetic response, especially for plant-based individuals.
- Takes 2 grams of glycine before bed for sleep.
Dr. Eric Berg · Glycine · recommends
- Recommends Glycine as a cofactor, especially for collagen.
- Recommends L-lysine because it competes with L-arginine, which the virus needs to reproduce, thus blocking the virus from getting arginine and starving it off.
- The amino acid leucine is important for muscle growth, but getting sufficient protein is just as essential for maintaining muscle mass.
- Mentions that animal protein provides leucine, an amino acid beneficial for muscle building.
- Recommends getting enough leucine, a key amino acid for muscle growth, to help prevent and correct muscle loss.
- Recommends taking glutamine or consuming foods high in glutamine to block the effects of grains.
- Glycine is classified as a non-essential amino acid because the body can make it, but many people are still deficient. It plays a critical role in red blood cell health, DNA and RNA production, bile salts, and glutathione, and is vital for the immune system and quality sleep.
- States that glycine is a powerful anti-aging secret that most people don't know about, and that many people are deficient despite it being a non-essential amino acid.
- Explains that glycine is essential for bile production, glutathione production, and immune function, and that consuming high-quality collagen can help increase glycine intake rather than taking a separate supplement.
- States that glutamine is an important amino acid for colon cells and is essential for intestinal permeability, greatly supporting the gut and benefiting inflammatory conditions.
- Dr. Berg states that a chronic deficiency in glycine could be the cause of joint aches, difficulty sleeping, and gut health issues, as it is essential for building collagen.
- Dr. Berg states that most glycine in the diet comes from collagen.
- Explains that leucine is an essential amino acid that signals muscles to grow, and its requirements increase with age, making it important for maintaining muscle after menopause.
- Used to take 3 grams of glycine before bed as a remedy to help with sleep, but now prefers magnesium glycinate to get both benefits.
Bryan Johnson · Glycine · uses
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- He takes 2 g of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of glycine before bed for sleep.
- He takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Bryan Johnson takes Taurine daily as part of his Longevity Mix, which supports heart health, provides antioxidant protection, and supports immune health.
Dr. Rhonda Patrick · Taurine · neutral
- Mentions that taurine depletion is a concern raised in long-term animal studies regarding Beta Alanine, though not observed in human trials, and notes that one can supplement with taurine, which is a beneficial compound.
- Notes that foods high in leucine are going to really support muscle protein synthesis.
- Supplements with glutamine.
- Always packs Glutamine when traveling, taking a baseline of 5 g/day and increasing to 15-20 g/day when sleep-deprived or exposed to illness, as it is an important fuel source for immune function.
- Rhonda takes 2 grams of Glycine before bed for sleep.
- Recommends glycine as a better option for a sleep-promoting supplement.
- Warns that Glutamine has stimulating properties that increase arousal, interfering with sleep onset, and should be avoided too close to bedtime.
- Recommends Glycine as a sleep supplement that promotes relaxation and reduces nighttime awakenings, offering meaningful improvements to sleep quality.
- Warns against taking glutamine at night for sleep because it is activating and can cause insomnia, citing examples of athletes who experienced this.
- Notes that glycine seems to promote inhibitory effects and suggests that if someone is taking amino acids at night for recovery, one with extra glycine would be better.
- Uses glycine, taken about 30-60 minutes before bed, as it may improve subjective sleep quality due to its nervous system effects.
- Uses 5 grams of L-Glutamine to support gut-immune axis integrity and may reduce infection risk during travel.
- Says L-Glutamine has been added to their supplement stack recently, convinced by Dr. Rhonda Patrick on its benefits.
- Rhonda's current supplement routine includes Glutamine.
Dave Asprey · Tyrosine · recommends
- Dave explains how L-tyrosine gives your brain the raw materials to make focus chemicals, and mentions the dose and timing that work.
- Dave Asprey explains that a 2017 study in rats found taurine pretreatment reduced several behavioral and biochemical effects of chronic unpredictable stress, but notes this does not show that taurine treats depression in humans.
- Mentions that taurine, a common longevity molecule, affects the sense of smell, but they do not know why it works.
- Recommends GlyNAC (glycine and NAC together) as very affordable amino acids that he would bet his coffee on if he had to choose just one thing for longevity, as they help the body make glutathione, the master antioxidant.
- Dave Asprey takes taurine, acknowledging it's cheap and safe, but notes that while mouse studies show spectacular longevity benefits, human data is currently only observational and lacks randomized longevity trials.
- Uses L-Tyrosine, an amino acid, to provide the brain with raw ingredients to make dopamine and norepinephrine, which activate the focus switch. He takes 500 mg every morning and advises starting with that dose and working up if needed, ideally on an empty stomach.
- Dave discusses safe upper limits for glycine before it starts working against you, mentioning oxalate crystal and Parkinson's-like risks of overdoing it.
- Dave Asprey warns that taking too much glycine, such as 10-30 grams a day, can lead to the formation of razor-sharp calcium oxalate crystals, similar to eating high-oxalate foods, and can contribute to diseases of aging.
- Asks what happens if you put glutamine in the skin, suggesting that manipulating amino acids in the skin and elsewhere is a fertile ground for more research.
- Mentions taurine as one of the ingredients in the Ageless Cocktail, which is designed for longevity.
- Recommends taking 2 grams of glycine to level out blood sugar.
- Dave Asprey explains why taurine remains popular in energy drinks and pre-workouts despite limited scientific evidence, what dosages and activity types future research should test, and why a reality check on a billion-dollar supplement category is exactly the kind of truth biohackers need.
- He takes 2 grams of Glycine before bed for sleep.
- Mentions that some drivers might use tyrosine to balance some of the caffeine.
Dr. Mark Hyman · Glutamine · neutral
- Mentions glutamine as something that might be helpful for gut repair.
- Dr. Mark Hyman, agreeing with the guest, highlights leucine as a primary amino acid important for muscle protein synthesis.
- Takes 2 grams of Glycine before bed for sleep.
- Recommends L-glutamine to help with gut barrier repair and healing leaky gut.
- Takes 2 grams of Glycine before bed for sleep.
- Takes 2 grams of Glycine before bed for sleep.
- Recommends glutamine to help repair the gut lining.
- Takes 2 grams of Glycine before bed for sleep.
- Recommends glycine, an amino acid often lacking in modern diets, for its potential role in overall health.
- Recommends supplementing with glycine, an amino acid often not obtained enough, which may have a role in overall health.
- Takes 2 grams of glycine before bed for sleep.
- Takes 2 grams of glycine before bed for sleep.
- Notes that Paleo Valley's bone broth protein is rich in glycine, an amino acid we often don't get enough of, and that glycine may have a role in overall health.
- Recommends glycine, an amino acid, for supporting sleep quality by helping to lower core body temperature and promote deeper, more restorative sleep.
Peter Attia · Glycine · neutral
- Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
- Mentions that threonine is important for mucin production in the gut.
- States that leucine is critical for muscle protein synthesis and recommends around 8 or 9 grams a day for optimal muscle health.
- Recommends two to three grams of leucine a day for muscle health, with optimal health probably around eight or nine grams.
- Mentions that they also see positive effects of glycine, among other things.
- Mentions that taurine supplementation in mice and other species appears to prolong life, referencing V.J. Adav's work, but notes that it is unclear if the same applies to humans.
- Recounts a story where a vegan doctor chastised him for suggesting ingesting five grams of leucine during a workout due to its negative effect on mTOR and potential link to cancer, which Peter Attia found amusing.
- Mentions that taurine supplementation in mice and some other species appears to prolong life in VJ Addev's work, but it's unclear if the same applies to humans.
- Mentions that collagen tends to be rich in glycine, among other amino acids.
- Warns that there is no benefit to supplementing leucine specifically if one is already consuming enough high-quality protein, and notes that leucine tastes horrible.
- Notes that many plant-derived proteins are low in methionine, and some meat alternatives are fortified with it.
- Mentions that estimations suggest two to three grams of Leucine in a meal will induce a rapid increase in circulating Leucine, stimulating muscle protein synthesis.
- Highlights that leucine content is an important factor in the anabolic response, and adding free leucine to casein can increase its anabolic effect.
- Recommends focusing on getting enough methionine, especially for plant-based patients, to ensure adequate amino acid intake for muscle protein synthesis.
RAL Summary
Members OnlyTier 4 for Teeth
Tier 4 because the supporting studies mostly used toothpastes, rinses or gels rather than a swallowed supplement, every ingredient amount is hidden in a blend, and no reviews were counted.
- Emerging: not enough evidence to rank higher yet.
- L-Lysine: amount hidden in a blend
- L-Glutamine: amount hidden in a blend
- L-Arginine: amount hidden in a blend
- Alpha-Glucan Oligosaccharide: amount hidden in a blend
- L-Phenylalanine: amount hidden in a blend
- Taurine: amount hidden in a blend
- Alpha Lipoic Acid: amount hidden in a blend
Where the evidence disagrees: 22 of the 96 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Oral health, Musculoskeletal system, Digestive system
Combine with: Because the ingredients are unidentified, build a tooth-supportive stack from proven components. Calcium (citrate or microcrystalline hydroxyapatite) with vitamin D3 supports enamel and dentin mineralization. Vitamin K2 (MK-7) helps direct calcium to bone and teeth. Magnesium supports mineral balance. Vitamin C and CoQ10 support gum and connective tissue health, and xylitol or a nano-hydroxyapatite toothpaste helps reduce cavity-causing bacteria and remineralize enamel. Pair these with good oral hygiene, fluoride as advised by your dentist, and regular dental checkups. Check with a healthcare provider before combining supplements, especially if you take medications.
Possible side effects: No major side effects reported.
Supplement Facts
Proprietary Blend 677 mg · L-Lysine 0 · L-Isoleucine 0
Supplement Facts
Serving Size 1 Capsule(s)
Servings Per Container 200
Amount Per Serving% Daily Value
| Proprietary Blend | 677 mg | † |
| L-Lysine | 0 | † |
| L-Isoleucine | 0 | † |
| L-Glutamine | 0 | † |
| L-Tyrosine | 0 | † |
| L-Threonine | 0 | † |
| L-Alanine | 0 | † |
| L-Leucine | 0 | † |
| L-Histidine | 0 | † |
| L-Arginine | 0 | † |
| L-Aspartic Acid | 0 | † |
| L-Valine | 0 | † |
| Ornithine-{alpha}-Ketoglutarate | 0 | † |
| L-Methionine | 0 | † |
| Alpha-Glucan Oligosaccharide | 0 | † |
| L-Glutamic Acid | 0 | † |
| Glycine | 0 | † |
| L-Phenylalanine | 0 | † |
| N-Acetyl-L-Tyrosine | 0 | † |
| L-Serine | 0 | † |
| Taurine | 0 | † |
| L-Proline | 0 | † |
| Alpha Lipoic Acid | 0 | † |
† Daily Value not established.
Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate.
Directions: Directions: As a dietary supplement, take one to two capsules daily, or as recommended by a health care professional. To be used as a dietary supplement in a normal food program. It is recommended that this product be taken with vitamins and minerals.
Barcode (UPC) 683268100202 · Label source: NIH label database · Report a label change
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Graded November 7, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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