NaturaLife Labs Organic Ashwagandha 2100 mg per Serving – Full Spectrum Root Powder and Standardized Extract (Withanolides) – 100 Capsules – Vegan – Non-GMO, Gluten-Free Review
Organic Ashwagandha 2100 mg – 100 Capsules is presented on the NaturaLife Labs store as a Best Seller and is listed at $16.95 for a one-time purchase, with a subscription option priced at $14.41 after a 15% saving and a monthly delivery frequency. The product description states that it is made with organic ashwagandha root powder and root extract for a full-spectrum supplement. Each serving provides 2,100 mg, including organic ashwagandha root powder, standardized root extract at 2.5% withanolides, and organic black pepper. The product is described as USDA Certified Organic, Non-GMO, Gluten-Free, and Vegan. The page states that it contains no fillers, magnesium stearate, dioxides, or artificial additives. It is described as manufactured in the USA in a GMP-compliant facility using globally sourced ingredients. Shipping information on the page says all orders ship via USPS First Class in 2 to 5 business days. The page shows a 4.5 rating from 50,895 Amazon customer reviews. Pay over time options are offered for orders over $35.00 through Affirm, subject to eligibility. The page also lists NaturaLife Labs contact details: support email support@naturalifelabs.com and an address at 21515 Hawthorne Blvd, Suite 200, Torrance, CA 90503. A standard disclaimer appears on the page: these statements have not been evaluated by the Food and Drug Administration, and the product is not intended to diagnose, treat, cure or prevent any disease. The page also offers a back-in-stock notification signup for when the variant is unavailable, and other NaturaLife Labs products appear in the carousels, including Organic Maca Root, Acetyl L-Carnitine, and Probiotics 70 Billion CFU. The store's category menu includes Best Sellers, General Wellness, Urinary and Digestive Health, Energy and Performance, Probiotic 3 IN 1, and Shop All. Reviewers on this page describe the product in terms of presentation, strength, and ease of swallowing, and one mentions it compared with gummy bears.
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Study, Trial or Testing Result Summary
Members Only26 human studies · 17 improved
The main ingredient, ashwagandha, has good human evidence for male hormones, but the exact amount in this product is hidden in a blend. A large review of 23 placebo-controlled trials with 1706 adults found ashwagandha raised testosterone in men by about 57 nanograms per deciliter more than placebo and lowered cortisol, without changing estradiol [1]. A second review of 20 trials also found higher testosterone and muscle strength [2]. In single trials, testosterone rose more than placebo in stressed adults [3], in overweight middle-aged men [4], in young men lifting weights taking 600 milligrams daily [5], and in men with low sexual desire, who also had better sexual function [6]. Not every trial agreed: two found testosterone rose in men but not more than on placebo. Black pepper, at 8 milligrams, has no good human evidence for male hormones. The only human study was a survey that did not give black pepper [7], and rat studies point both ways [8][9]. Iron, at 1 milligram, is well below the 12 milligrams studied, and that study gave iron together with vitamin A to boys with delayed puberty [10]. Animal and cell studies are never counted.
See all 26 studies →Hide the studies
- Across 23 placebo-controlled trials with 1706 adults, ashwagandha raised testosterone in men (about 57 ng/dl more than placebo) but not in women, and lowered cortisol, with no effect on estradiol.Hormonal Modulation with Withania somnifera: Systematic Review and Meta-Analysis of Randomized-controlled Trials.
- Across 20 randomized trials with 1249 adults, ashwagandha raised testosterone and muscle strength and improved memory and attention, but did not change body weight or body fat.Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review…
- In four small trials (mostly uncontrolled) of infertile men, 90 days of ashwagandha was linked to higher testosterone (17%), luteinizing hormone (34%) and better semen quality, but the evidence is too limited to be firm.Withania somnifera (Indian ginseng) in male infertility: An evidence-based systematic review and meta-analysis.
- A review of 32 randomized trials of herbs in men found ashwagandha root and leaf extracts, along with fenugreek, had positive effects on testosterone, though studies were small and varied.Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
- A review of 35 papers on herbs for sperm and testosterone listed ashwagandha among plants used for male reproduction, without giving specific results for it.The most important medicinal plants affecting sperm and testosterone production: a systematic review.
- In a review of 52 studies of testosterone boosters, most failed to raise testosterone, but ashwagandha was judged possibly effective for healthy men.Do "testosterone boosters" really increase serum total testosterone? A systematic review.
- In 102 boys aged about 14 to 15 with short stature and delayed puberty, 6 months of 12 mg daily iron plus weekly vitamin A sped growth (9.3 vs 4.0 cm per year) compared with no treatment and brought on puberty within 12 months, similar to hormone therapy.Vitamin A and iron supplementation is as efficient as hormonal therapy in constitutionally delayed children.
- In 84 recreationally active adults taking 300 mg daily for 90 days, strength and endurance improved more than placebo; testosterone rose in men (121 ng/dL) but the change was not different from placebo.Efficacy and safety of a sustained release ashwagandha root extract capsules on muscle strength and cardiorespiratory en…
- In 60 stressed adults taking 240 mg daily for 60 days, testosterone rose in men over time but not significantly more than placebo, while cortisol and DHEA-S fell more than placebo.An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A…
- In 60 stressed, anxious adults given 60 mg or 120 mg of ashwagandha extract for 60 days, testosterone rose 22% and 33% versus 4% in males on placebo, and morning cortisol fell by about two thirds.Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects…
- In 57 young men doing resistance training, 600 mg a day of ashwagandha root extract for 8 weeks led to greater testosterone increase (96.2 vs 18.0 ng/dL), muscle strength and size, and fat loss than placebo.Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled tria…
- In 57 overweight men aged 40-70 with mild fatigue, 8 weeks of ashwagandha extract (21 mg withanolide glycosides daily) raised DHEA-S 18% and testosterone 14.7% more than placebo, with no difference in cortisol, estradiol, fatigue or vigor.A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagand…
- In 50 men with low sexual desire, 600 mg a day of ashwagandha root extract for 8 weeks raised testosterone and sexual function scores more than placebo, while prolactin did not change.Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult ma…
- In 40 healthy adults aged 50-70 given 400 mg a day of ashwagandha root extract for 180 days, testosterone rose 15.7% in the men, thyroid hormones were unchanged, and the extract was well tolerated.Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blin…
- In overweight adults aged 40-75 with stress and fatigue, 400 mg a day of ashwagandha extract for 12 weeks raised free testosterone and luteinizing hormone in men compared with placebo, and reduced fatigue, but did not reduce stress more than placebo.Exploring the efficacy and safety of a novel standardized ashwagandha (Withania somnifera) root extract (Witholytin®) in…
- In a cross-sectional study of 773 adults in Germany, piperine, a marker of black pepper intake, was among the metabolites linked to androgen levels, but the study did not test black pepper supplementation and found no hormone benefit.Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabe…
- In 191 adults aged 18 to 65 taking ashwagandha root extract for 12 months, testosterone rose and cortisol fell, with few mild side effects and no control group.Safety of 12-Months Administration of Ashwagandha ( Withania somnifera ) Standardized Root Extract in Healthy Adults: A …
- In 97 people with transfusion-dependent beta-thalassaemia, two-thirds had at least one hormone disorder, and low sex hormone levels were most common and linked to genotype; higher blood iron levels were tied to thyroid and parathyroid problems, but iron was not given as a supplement in this study.Incidence of endocrine complications and clinical disease severity related to genotype analysis and iron overload in pat…
- In male rats, 200 mg/kg of black pepper alone over 28 or 56 days changed testosterone and semen measures compared with controls, but the abstract does not state the direction of the change for black pepper alone.A Comparative study on the effects of Yaji (Suya Meat sauce) and its spice constituents on the male reproductive profile…
- In gerbils exposed to bisphenol A, piperine at 20 mg/kg combined with curcumin reduced prostate inflammation and abnormal cell changes; hormone levels were not reported.Protective effect of the association of curcumin with piperine on prostatic lesions: New perspectives on BPA-induced car…
- In mice given a toxic chemotherapy drug, piperine at 10 mg/kg for 8 days reduced testicular damage, oxidative stress and cell death.Piperine mitigates oxidative stress, inflammation, and apoptosis in the testicular damage induced by cyclophosphamide in…
- In hyperlipidemic male rats, piperine at 40 mg/kg for 10 weeks raised testosterone and thyroid hormone levels toward normal and lowered lipids and insulin.Piperine, an active principle from Piper nigrum, modulates hormonal and apo lipoprotein profiles in hyperlipidemic rats.
- In diabetic male rats, black pepper fruit extract at 122.5 mg/kg for 8 days improved erection, libido and Leydig cell count, and 245 mg/kg improved sperm count and motility.Fruit Extract of Black Pepper (Piper Nigrum L.) Ameliorates Male Reproductive Dysfunction in Alloxan-Induced Diabetic Ra…
- In diabetic male rats, black pepper fruit extract at 122.5 mg/kg for 8 days improved erection and libido, and 245 mg/kg raised intratesticular testosterone and sperm concentration.Effects of Black Pepper (Piper nigrum L.) Fruit Extract on Sexual Function, Hormonal Parameters, Sperm Parameters, Testi…
- In male rats, piperine at 10 mg/kg given with a med for 28 days caused reproductive toxicity, with more oxidative stress and lower antioxidant enzymes in the testes.Read the study on PubMed (40246250) →
- In male rats, piperine at 10 mg/kg daily for 30 days lowered intratesticular testosterone and damaged testis tissue, although blood testosterone stayed normal.Effects of piperine on testis of albino rats.
Review Totals and Summary
Members Only53,230 reviews · 88% positive
This NaturaLife Labs Organic Ashwagandha product, available in capsule form, has garnered approximately 50895 ratings across various stores, with customer feedback being largely positive. Reviewers frequently praise its effectiveness and value. **What it did for them** Many customers report significant positive effects from taking these ashwagandha capsules. Users mention improved focus, with one stating it "helps me to keep focus on my work and to study." A common theme is better sleep and reduced stress; one reviewer experienced "sleeping amazingly and my cortisol levels were lower," also noting "My face is less puffy." Another found it "helped quite a bit with stress, also libido," leading to better rest and sleep. Some consider it an essential supplement they "can't live without it." **Complaints** Concerns are limited among the visible feedback. The primary hesitation raised by reviewers relates to the size of the capsules for swallowing. Additionally, one customer noted that the effects were still being evaluated in the short term, reporting "So far no effects" but not as a negative outcome, rather an ongoing assessment. No explicitly negative reviews were found among the visible entries. **Pill Size and Form** The product is sold as capsules. Customers generally find the capsule size manageable, with one reviewer stating it is "ok to swallow this size of tablet" with water or juice. The presentation of the capsules is also favored, with one customer noting it has "much better presentation than the gummy bears" (other forms of this product, such as gummies, are not the focus of this summary). **Value for Money** The product is frequently highlighted for its good value. Reviewers describe the price as "great" and "OK for this product," especially considering the perceived strength and effectiveness. The overall sentiment is that the product offers good value for its cost. **Who it suits and who it did not** This ashwagandha appears to suit individuals seeking support for stress, sleep issues like insomnia, and those looking to improve focus. Customers with high cortisol levels or seeking libido support have also reported positive outcomes. There is no clear indication from the feedback of specific groups for whom the product did not work or was unsuitable, beyond the general observation that effects may take time to manifest for some users.
Biohacker Summary
Members Only9 of 10 recommend it
The panel's main ingredient here is black pepper, and nine of the ten panelists spoke about it, with opinion leaning positive. Four of them recommend or use it, mainly paired with turmeric or curcumin, because its active compound helps the body absorb curcumin and slows its breakdown; one of them adds it to eggs and another to turmeric tea. Three give cautions: one says many people are sensitive to it, one says to avoid pepper extract if androgen hormone levels are low or the body responds poorly to them, and one stopped using the extract after hearing about its downsides. Two stayed neutral, with one only noting it is high in oxalates. Ashwagandha is a smaller ingredient in this product, and the panel mostly likes it for stress, sleep and cortisol, though one advises a two week break after two weeks of use.
See all 10 biohackers →Hide the biohackers
Dr. Eric Berg · Black Pepper · recommends
- Dr. Eric Berg recommends pairing black pepper with turmeric to improve curcumin absorption.
- Warns against iron supplements, suggesting instead to get iron from red meat or liver.
- Dr. Berg states that when nutrients like iron are too low, fatigue and weakness can follow.
- Does not recommend taking iron supplements or cooking in iron skillets because the body has no mechanism of getting rid of iron unless one donates blood or is a menstruating female.
- Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
- Mentions that grass-fed liver has heme iron, the most bioavailable form of iron that prevents anemia.
- Notes that black pepper aids in the absorption of Curcumin.
- Dr. Eric Berg recommends adding black pepper to eggs to support satiety, antioxidant potential, cardiovascular, and liver health.
- Dr. Berg warns that too much iron can be damaging to the body and advises focusing on food sources to avoid overconsumption.
- Recommends ashwagandha, suggesting 250 milligrams per day over time to increase stress tolerance and help the cortisol receptor.
- Warns that too much iron, especially the ferrous sulfate or fumarate type found in many supplements, is corrosive and oxidizing, can mess with the liver, and create inflammation, noting that males have no natural way to excrete excess iron.
- Notes that tannins in tea bind iron, blocking its absorption.
- Mentions that vertical ridges on nails could indicate an iron deficiency.
- Discusses iron deficiency and the concern of excess iron accumulation in the body, noting that iron comes from naturally iron-rich foods and can be added to processed foods and supplements.
Dr. Mark Hyman · Black Pepper · recommends
- Recommends seasoning turmeric with black pepper to help the body absorb more nutrients.
- States that iron helps red blood cells carry oxygen, and a deficiency can make one feel like they are running on low power mode.
- Lists ashwagandha as an herb that can help lower anxiety or depression symptoms.
- Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Notes that a woman patient had very low iron.
- States that they get the whole picture when it comes to iron, looking at ferritin, iron reserves, iron in the blood, iron saturation, and iron binding capacity to spot problems before full-blown anemia.
- Mentions iron as an example of a common nutritional deficiency.
- Notes that many Americans are deficient in iron, which affects mood and brain function.
- Notes that black pepper, along with gentle heat, improves the absorption of curcumin in Paleovalley's turmeric complex.
- Recommends testing Iron as a biomarker before training for fitness.
- States that low iron, specifically a ferritin level less than 45, is a big hidden cause of insomnia, affecting up to half the population.
- Notes that there was a recent study on ashwagandha for sperm health, indicating it's an evolving area of research.
- Mentions that they check iron levels as part of evaluating mental illness biomarkers.
- Recommends carefully looking at iron, thyroid, and cortisol levels as they all play a role in affecting cognitive function and mental health.
Thomas DeLauer · Black Pepper · recommends
- Recommends taking black pepper with curcumin to increase its bioavailability, as curcumin gets metabolized before it can do anything without it.
- Recommends giving any iron intervention a couple of months before deciding if it works, and suggests increasing heme iron through red meat or liver intake.
- Recommends ashwagandha extract, noting a study where 57 overweight men over 40 saw a 14.7% increase in testosterone and an 18% increase in DHEA over 16 weeks, suggesting it removes the cortisol block suppressing the entire hormonal cascade.
- Compares iron content in spinach (2.7mg) and beef (2.6mg), but emphasizes that beef's heme iron absorbs at about 25%, while spinach's non-heme iron absorbs at 2-8%.
- Mentions ashwagandha as part of a full testosterone protocol, supporting production through different pathways.
- Recommends iron from meat, specifically red meat and beef liver, stating that it is a crucial part of the mechanistic triad for thyroid hormone function and is iron-dependent for iodine incorporation into thyroid hormone.
- Recommends mixing curcumin with black pepper (piperine) for general inflammation, as piperine inhibits the breakdown of curcumin, increasing its bioavailability by up to 2,000%.
- Notes that iron is essential for delivering oxygen to muscles and the brain, making it an important cofactor for signals to reach their targets.
- Recommends assessing iron along with selenium and iodine for optimal thyroid function, suggesting red meat as a source of iron.
- Recommends getting heme iron from real food sources like organ meats, red meats, or pumpkin seeds, and warns against iron supplements due to potential oxidation and issues with copper levels.
- Warns against overdoing iron supplementation unless truly needed, especially if ferritin levels are high, as ferroptosis is iron-dependent and excess iron can increase ferroptotic risk.
- Recommends black pepper with turmeric because its piperine blocks liver clearance, allowing curcumin to absorb and shut down inflammatory response.
- Recommends ashwagandha, noting it modulates the HPA axis and dropped cortisol by approximately 23% in 60 days, but advises cycling it, especially if feeling emotionally numb.
- Recommends good quality heme iron from food sources like liver and beef for preventing insulin resistance and type 2 diabetes, supporting glucose control, and energy regulation, but warns against iron supplements.
Ben Greenfield · Black Pepper · warns
- Advises watching out for black pepper, as it is eliminated in core AIP and many people are surprisingly sensitive to it.
- Ashwagandha, taken as 120–1,000 mg for at least 6 weeks, with most studies providing a dose of 400–600 mg/d, can lower cortisol levels, improve sleep quality, and enhance cognitive resilience for athletes during challenging phases consisting of high-volume resistance training.
- Recommends testing for and replenishing iron if levels are low, as it can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
- Notes that ashwagandha is an ingredient in MTE.
- Mentions Ashwagandha as a supplement people cycle through when still sleeping poorly, suggesting it might not be addressing the true sleep problem.
- Notes that one can eat iron-rich foods or supplement with iron, but still feel exhausted if iron is not the missing piece, emphasizing that focusing on a single mineral in isolation can support a number on a lab test rather than the system itself.
- Notes that ashwagandha is a nightshade herb, but it is taken as a supplement and not used for cooking.
- Mentions iron as a common deficiency.
- Recommends a nutritious diet including iron, as it is critical for brain development.
- Notes that the guidelines mention iron supplementation for infancy and early childhood.
- Recommends combining black pepper with Triphala and Himalayan pink salt as a powder to brush with, as it is astringent, drives up inflammation and infection in the gums, is refreshing, and prevents plaque.
- States that Ashwagandha helps regulate stress response and steady the nervous system, influencing biological systems tied to sleep quality.
- Has found that adaptogens like ashwagandha, taken about half an hour before using the Shift Wave, seem to enhance its effects on tuning up the nervous system. He also found it helped him and his co-founder achieve slower respiratory heart rate coherence.
- Started thinking about getting more heme-based iron in his diet after a podcast about reasons people feel fatigue.
Dave Asprey · Black Pepper · stopped
- Dave Asprey used to research black pepper extract but changed his mind about its use after a discussion with Christian DPO, who highlighted its downsides.
- Dave Asprey notes that ashwagandha, when taken as a real standardized extract at a real dose, genuinely lowers cortisol and shows effects on stress and sleep quality in randomized trials, but lacks polysomnography data.
- Dave Asprey discusses ashwagandha as part of an adaptogen trio that works together for stress response and human performance.
- Mentions ashwagandha as an adaptogen in MTE that helps blunt the cortisol spike.
- Warns that if a doctor diagnoses anemia, one should not assume they just need more iron, as low hemoglobin doesn't always mean low iron and the issue can sometimes be how well the body is using iron.
- Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for iron, which is associated with impaired recovery.
- Advises against ashwagandha for low cortisol, stating that salt and water are needed instead.
- Warns that ashwagandha can raise testosterone in women, causing irritability, and therefore needs to be cycled.
- Dave Asprey mentions ashwagandha as a supplement and cofactor that supports thyroid activation.
- Recommends ashwagandha as a cofactor that can help thyroid function, especially with conversion issues.
- Recommends ensuring iron levels are good as it is a cofactor that can help thyroid function, especially with conversion issues.
- Dave Asprey lists ashwagandha as part of a supplement stack that supports healthy hormone levels.
- Discusses ashwagandha as a common adaptogenic herb used by biohackers to deal with stress, noting it was banned in Denmark and can cause anhidonia and reduced ability to reach orgasm at higher doses.
- Egg yolks, particularly raw egg yolks, fatty cuts of meat, choline sources like that, making sure there's enough iron and a lot of the micro minerals, trace minerals, things like that. Those would be really important for bone marrow because mineral deficiencies are going to block that at the start.
Andrew Huberman · Black Pepper · warns
- Recommends avoiding bioavailable curcuminoids like black pepper extract if someone's DHT is already low or if they have somewhat insensitive androgen receptors.
- States that Iron is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
- He shares science-based tools for modulating aggression, including supplementation with ashwagandha.
- Warns that while ashwagandha is a potent inhibitor of cortisol, chronic supplementation for longer than two weeks can disrupt other hormone and neurotransmitter pathways, so it should be used with a two-week break after two weeks of use.
- Warns that excess iron will increase the number of senescent cells in the body, which accumulate as people get older and cause inflammation and cancer. He notes that people who are healthy and have a fairly vegetarian diet often have slightly low iron levels but super amounts of energy.
- Recommends Ashwagandha as a supplement to reduce cortisol.
- Notes that about 50% of the population is iron deficient.
- Mentions that the podcast will review the role of iron in treating depression.
- States that B12, folate, and iron are essential to mitochondrial function and if deficient, mitochondria will not function properly, which is consistent with the mitochondrial theory of neuropsychiatric disorders.
- Explains how to optimize hormone levels through supplements such as ashwagandha.
- Mentions ashwagandha as a potent commercial compound in supplement form that can be used to reduce chronic stress, especially late in the day, by significantly decreasing cortisol.
- Discusses Ashwagandha as a supplement to better manage stress.
- Uses ashwagandha when feeling particularly stressful to lower anxiety and cortisol, but does not take it year-round or on a regular basis.
- Takes ashwagandha for sleep.
Bryan Johnson · Black Pepper · uses
- Adds black pepper to turmeric because a compound in pepper called piperine boosts the power of turmeric by slowing the breakdown of curcumin in the gut and liver, making its antioxidant, anti-inflammatory, and metabolic benefits last longer.
- Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
- Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
- Drinks his Blueprint longevity mix with additional morning supplements, including ashwagandha.
- States that Blueprint Ashwagandha can be used to stabilize mood.
- Mentions that Ashwagandha is included in the LA Longevity Mix, which condenses his 100 daily pills into a drink.
- Mentions ashwagandha as a potential therapy that could positively influence sperm health.
- Takes 10 milligrams of heme iron to get his iron levels up, as they are borderline.
- Mentions ashwagandha as an ingredient in his 'bag of goodies', indicating he uses it.
- Takes ashwagandha for anti-anxiety, improved cortisol management, improved sleep, and increased testosterone.
- Recommends adequate Iron for hair health, noting it is in the Blueprint stack.
- Recommends supplementing with iron for brain health for both the mother and the baby during pregnancy.
- Recommends ashwagandha at 300 to 600 mg daily to support stress resilience and overall well-being during the luteal phase for women.
- Ashwagandha + Rhodiola is part of the Blueprint protocol for energy and stress support.
Siim Land · Black Pepper · neutral
- Lists black pepper as an herb or spice that is high in oxalates.
- Mentions that iron is a mineral necessary for making collagen.
- Recommends Ashwagandha for stress, sleep and performance, based primarily on human research, especially randomized controlled trials showing measurable benefits.
- Lists Ashwagandha as one of 15 supplements backed by human studies.
- Notes that Ashwagandha is one of several supplements with human evidence.
- States that excess iron promotes oxidative stress and inflammation, which increases heart disease risk.
- States that ashwagandha, unless contaminated, is not going to raise liver enzymes.
- Stopped taking ashwagandha because it immediately caused a mouth sore.
- States that ashwagandha consistently reduces stress and anxiety in randomized controlled trials.
- States that Ashwagandha helps with testosterone primarily in stressed out or poor sleeping people.
- States that ashwagandha has strong evidence for increasing testosterone, mostly in stressed or infertile men.
- Notes that iron deficiency is found in children with premature graying of hair and that some people get gray hair due to iron deficiency.
- Recommends ensuring sufficient iron intake, especially during pregnancy and early life, to prevent mental developmental and cognitive issues.
- States his iron level is 103 micrograms per deciliter, which he considers a good result, and advises that men should aim for lower iron levels to reduce the risk of heart disease and aging.
Dr. Rhonda Patrick · Black Pepper · recommends
- Adds black pepper to her turmeric tea because the piperine in it stops enzymes in the liver from clearing out polyphenols, thus extending their half-life.
- Recently found out he needed to get on an iron supplement and noticed he gets less sore in his training after taking it.
- Advises that menstruating women should ensure they are getting enough iron.
- Recommends Ashwagandha supplementation, specifically standardized for withanolides (KSM-66 at 5% or Sensoril at 10%), to indirectly boost testosterone by reducing cortisol levels, and also to improve anxiety, stress resilience, and sleep quality.
- Recommends ashwagandha, specifically patented extracts like Sensoril or KSM66 standardized to sufficient quantities of withanolides, for its indirect effect on testosterone by suppressing cortisol and stress response, which can be beneficial for anxious individuals and improve sleep.
- Warns that iron is not an innocuous supplement and should not be taken aggressively without proper testing, as it can be complicated and has significant downsides if levels are not understood.
- Is very bullish on Ashwagandha, citing meta-analyses showing improved lean mass, strength, sleep, and stress management. He notes it also raises testosterone but not enough to explain the lean mass changes.
- Discusses ashwagandha.
- Uses ashwagandha as a supplement to help with sleep.
- Dr. Patrick explains that breast milk is incredibly low in iron, and by six months, infants can develop iron deficiency anemia, so pediatricians recommend introducing iron-rich complementary foods at that time.
- Rhonda discusses Dr. Lithgow's work on how excess dietary iron affects protein homeostasis in worms, noting that increased iron levels in the diet accelerated aging and the accumulation of insoluble proteins.
- Dr. Patrick takes some iron during menstruation.
- Increased iron levels in the brain worsen cognitive test performance by as much as 10% in older adults, a phenomenon linked to brain atrophy and decline in memory and attention.
- Iron plays a central role in health across the lifespan. It forms the core of hemoglobin, the molecule in red blood cells...
Peter Attia · Ashwagandha · neutral
- Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
- Finds ashwagandha a little bit helpful for sleep, though notes it may not be for everyone.
- Finds ashwagandha "a little bit helpful" for sleep, but notes that it may not be for everyone.
- Recommends iron supplements for women of reproductive age who are iron deficient.
- Finds ashwagandha a little bit helpful for sleep, but notes it may not be for everyone.
- States that the data for ashwagandha are weak.
- Discusses the current evidence for ashwagandha's effects on sleep, stress, and anxiety.
- Mentions ashwagandha as an evergreen shrub historically used in traditional Indian medicine for indications such as sleep, stress, and immune health.
- Notes that deficiencies in certain vitamins and minerals, such as iron, can be a cause of hair loss in women.
- Delves into the crucial yet often overlooked topic of iron and iron deficiency.
- Explains that humans consume about 10 to 20 milligrams of iron per day, absorbing roughly 10% of that, which is 1 to 2 milligrams per day, perfectly offsetting the 1 to 2 milligrams lost daily.
- Peter emphasizes the importance of consuming an adequate amount of iron daily to prevent deficiency.
- Mentions ashwagandha as something that can help with sleep in the setting of chronic stress and hypercortisolemia.
- Takes 600 mg of Solgar ashwagandha at night, having recently switched to this brand and returned to taking it after a previous hiatus.
RAL Summary
Members OnlyTier 3 for Hormone Balance for Men
88% of its 53230 reviews are positive and animal studies support Black Pepper.
Where the evidence disagrees: 6 of the 26 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Endocrine system, Reproductive system, Nervous system, Muscular system
Combine with: To enhance the benefits of Ashwagandha for male libido, consider combining it with supplements that further support testosterone production, blood flow, and overall sexual health. Fenugreek and Tongkat Ali are known to synergistically boost testosterone levels. L-Arginine or L-Citrulline can improve nitric oxide production, supporting healthy blood flow essential for erectile function. Additionally, Maca root is often used to enhance libido and sexual vitality, while Panax Ginseng can contribute to energy and sexual performance.
Possible side effects: No major side effects reported in the studies given. Some reviewers found the capsules large to swallow.
Supplement Facts
Total Carbohydrates 2 g · Iron 1 mg · Total Blend 2100 mg
| Calories | 10 | |
| Total Carbohydrates | 2 g | 1% |
| Iron | 1 mg | 6% |
| Total Blend | 2,100 mg | † |
| Organic Ashwagandha (Withania somnifera) (Root) Powder, Organic Ashwagandha (Withania somnifera) (Root) Extract (2.5% Withanolides) | 0 | † |
| Organic Black Pepper (Piper nigrum) (Fruit) (Extract) | 8 mg | † |
Other ingredients: Organic Pullulan (Capsule).
Directions: SUGGESTED USE: As a dietary supplement, take three (3) capsules daily, with meals or as directed by a healthcare practitioner.
Label source: Naturalifelabs · Report a label change
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