Nature Made Prenatal Multi Review

Nature Made Prenatal Multi is a multivitamin and mineral supplement in tablet form. One tablet is a serving, and each container holds 90 servings. Per tablet the label lists vitamin A 770 mcg, vitamin C 85 mg, vitamin D3 25 mcg, vitamin E 15 mg, vitamin K 90 mcg, folate 1330 mcg DFE, vitamin B12 5.2 mcg, iron 27 mg, calcium 250 mg, iodine 150 mcg, magnesium 45 mg and zinc 11 mg. It also lists thiamine 1.4 mg, riboflavin 1.4 mg, niacin 18 mg, vitamin B6 1.9 mg, biotin 30 mcg and pantothenic acid 6 mg. Other ingredients include cellulose gel, modified food starch, maltodextrin, hydrogenated soybean oil, gelatin and magnesium stearate, among others. The directions printed on the label say adults take 1 tablet daily with water and a meal. Buyers most often praise the price and the amount in the bottle, and many call the tablet easy to swallow. The most common complaint is a fishy or orange smell reported by some.

Product Focus: Thyroid HealthAlso covers:HormonesDigestionRanked among:MultivitaminsMultivitamins for women
Tier ⓘ
Tier 2 · Rank 5
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 5 within Tier 2 for Thyroid Health; 5 of 58 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
86 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
93% of 13,558
Biohacker Mentions
9 of 10

Study, Trial or Testing Result Summary

Members Only235 human studies · 59 improved

4 of these 235 human studies gave the ingredient by drip or injection, not by mouth.

235 human studies59 improved129 no effect786,020 people studied

Iodine, at the full studied dose of 150 micrograms, has the clearest support for thyroid health, mainly in people who do not get enough. In iodine-poor areas, supplements in pregnancy cut childhood cretinism by about 73% [1], and daily iodine shrank goitre by about 37% [2]. Too much iodine can harm the thyroid [3]. Iron, also at a full dose, helped thyroid size and hormones in iron-deficient children and teenage girls [4][5]. Taking iron with meds weakens it, so space them about 4 hours apart. Vitamin D results are mixed: one review found lower thyroid antibodies [6], another found no clear benefit [7]. Zinc is at a full dose only at the three daily servings members are told to take. Adding zinc to meds raised thyroid hormone in a pooled review, with low certainty [8], and other trials found no change [9]. Vitamin A, vitamin C and magnesium are below the doses studied [10][11][12]. The B vitamins, vitamin E, vitamin K and calcium have no evidence of helping the thyroid [13]. Biotin can distort thyroid blood test results [14]. Animal and cell studies are never counted.

See all 235 studies →Hide the studies

Review Totals and Summary

Members Only13,558 reviews · 93% positive
13,558 reviews · Amazon 13,168 · CVS 233 · Walgreens 102 · Walmart 55
93% positive3% neutral4% negative

Buyers rate this prenatal multivitamin well overall. It carries about 13558 ratings across the stores that sell it, and 79% of the starred reviews give 4 or 5 stars. **What buyers say it did for them:** Most praise is about how it sits with them, not about results. One buyer calls it "Easy to take, easy on the stomach." A husband writes it is "the only prenatal my wife tried that didn't make her nauseous." One long term user says they have "never been able to grow nails" and have taken it for a very long time. Another takes it while hoping to get pregnant and says, "I know they aren't hurting." A repeat buyer says it is their third pregnancy on it with no problem. **What they complain about:** The biggest complaint is smell. One person says the second bottle "smells fishy" after a fine first batch. Another says the orange and fish scent is nauseating, tied to memories of the glucose drink. Some complaints are about orders: one buyer got a different item than the one ordered, and another says a buy one get one offer sent only one bottle. One buyer cuts each tablet in half because the daily percentages on most vitamins are so high. **Taste, smell, pill size and form:** Buyers who like it call it an "easy to swallow medium sized tablet" with "no after taste." One says it tastes like most tablet multivitamins and is not as hard to swallow as expected, though they usually prefer a gel capsule. The smell is where opinions split, with some having no issue and others finding it hard to bear. **Value for money:** Price is the most repeated positive. Buyers write "Great value for your money" and "Great quantity for the price." Another says it "can't be beaten for the price and quality." **Who it seems to suit and who it did not:** It suits buyers who want a plain, low cost tablet and who have struggled with other prenatals making them queasy. It also suits those buying for a daughter or taking it before pregnancy. It did not suit people sensitive to smell, especially orange or fishy scents, or people who want smaller amounts per dose. One buyer says an OBGYN recommended it and that it is meant to be taken with folic acid and DHA.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Zinc is the main ingredient, and the panel leans toward it: eight of the ten spoke about it, with three recommending it, three using it, three staying neutral, and one warning. Reasons given include immune support, wound and tissue healing, testosterone, gut lining, longevity, and helping the body absorb vitamin C, and one panelist uses a zinc sunscreen on the skin. Forms and doses are sparse: one takes 15 mg in the morning, one pairs it with vitamin C for fall and winter, one pairs it with magnesium for sleep, and one gave a short course around surgery, though that panelist's stated amount of 30 grams a day reads as a warning, so shoppers should not copy it. One panelist named zinc carnosine for the gut, and no one said they stopped taking it. Magnesium is a smaller ingredient in this product, and many on the panel take it at night for sleep.}</br>

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Iodine · recommends
    • 8 Nov 2026 · recommends · Facebook ↗
      Recommends using povidone-iodine daily with a small bandage for skin tags and warts, stating it may help deactivate the virus behind these growths.
    • 8 Nov 2026 · Vitamin D · neutral · Facebook ↗
      Lists Vitamin D as an ingredient found in sardines.
    • 8 Nov 2026 · Vitamin B12 · neutral · Facebook ↗
      Mentions that one can of sardines provides 348% of the daily Vitamin B12.
    • 8 Nov 2026 · Calcium · neutral · Facebook ↗
      States that one can of sardines contains 382 mg of calcium.
    • 8 Nov 2026 · Vitamin A · neutral · Facebook ↗
      Mentions that the body relies on healthy fats to absorb essential vitamins like A, D, E, and K, which help support skin health, moisture, and normal cell function.
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends iodine as a trace mineral, noting that modern farming practices deplete it from the soil, leading to low levels in crops.
    • 7 Nov 2026 · recommends · Instagram ↗
      Dr. Eric Berg states that 80% of the body's iodine is concentrated in the thyroid, but other tissues like breast tissue, reproductive organs, and stomach also rely on iodine to function properly, emphasizing the importance of getting enough iodine even with a normally functioning thyroid.
    • 7 Nov 2026 · uses · YouTube ↗
      Introduces his new product, Plant-based Iodine Icelandic Sea Kelp, which he uses and recommends taking one vegetable capsule delivering 200 micrograms of plant-based iodine in the morning.
    • 7 Nov 2026 · Zinc · recommends · Facebook ↗
      Recommends zinc as a trace mineral, noting that modern farming practices deplete it from the soil, leading to low levels in crops.
    • 7 Nov 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D3 because it's nearly impossible to get enough from food and most people don't get enough sun, advising to aim for blood levels of at least 50 to 80 ng/mL.
    • 7 Nov 2026 · Vitamin D · neutral · Instagram ↗
      Dr. Berg states that when nutrients like vitamin D are too low, fatigue and weakness can follow.
    • 7 Nov 2026 · Vitamin B12 · neutral · Instagram ↗
      Dr. Berg states that when nutrients like vitamin B12 are too low, fatigue and weakness can follow.
    • 7 Nov 2026 · Calcium · warns · Facebook ↗
      Warns against calcium supplements, citing studies that link them to a higher risk of heart attack, especially in postmenopausal women, and suggests getting calcium from dairy instead.
    • 7 Nov 2026 · Vitamin A · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
  • Dr. Rhonda Patrick · Zinc · neutral
    • 6 Nov 2026 · neutral · Instagram ↗
      Mentions that getting too little zinc may play a role in declining testosterone levels, and that zinc helps the body make testosterone.
    • 8 Nov 2026 · Vitamin D · neutral · Instagram ↗
      Notes that vitamin D from sunlight, food, or supplements needs to undergo conversions in the liver and kidneys to become its active hormone form, calcitriol.
    • 8 Nov 2026 · Magnesium · recommends · Instagram ↗
      Explains that magnesium helps the body activate and metabolize vitamin D, and that magnesium intake has been associated with lower odds of vitamin D deficiency and insufficiency.
    • 6 Nov 2026 · Magnesium · neutral · Instagram ↗
      Mentions that getting too little magnesium may play a role in declining testosterone levels.
    • 4 Nov 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D supplementation has been associated with a 40% lower dementia risk, and low levels are linked to a 50 to 80% higher risk.
    • 3 Nov 2026 · Magnesium · recommends · X ↗
      Recommends getting enough magnesium, around 300–400 mg daily from diet and supplements, as it is an essential cofactor for vitamin D metabolism. Magnesium glycinate is a good form.
    • 1 Nov 2026 · Magnesium · neutral · YouTube ↗
      Mentions magnesium as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 1 Nov 2026 · Vitamin K · neutral · YouTube ↗
      Mentions vitamin K as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 1 Nov 2026 · Folate · neutral · YouTube ↗
      Mentions folate as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 31 Oct 2026 · Magnesium · neutral · YouTube ↗
      Explains that magnesium helps control blood pressure by boosting the production of substances that relax blood vessels and improve cardiovascular health, citing a meta-analysis that found magnesium supplementation at an average dose of 368 mg per day notably lowers both systolic and diastolic blood pressure.
    • 29 Oct 2026 · Magnesium · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 28 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting adequate vitamin D, noting that people taking vitamin D supplements have a 40% lower risk of dementia, while those with lower vitamin D have a 50-80% higher risk.
    • 16 Oct 2026 · Magnesium · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 5 Oct 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
  • Andrew Huberman · Zinc · neutral
    • 5 Nov 2026 · neutral · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 4 Nov 2026 · Magnesium · recommends · Instagram ↗
      Notes that Les Spellman's team includes 'Magnesium timed right' as part of their game plan to optimize recovery in unfavorable conditions.
    • 29 Oct 2026 · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 22 Oct 2026 · Magnesium · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 19 Oct 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 21 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 14 Sep 2026 · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 7 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
  • Ben Greenfield · Zinc · warns
    • 29 Oct 2026 · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Vitamin E · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 29 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 22 Oct 2026 · Magnesium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 21 Oct 2026 · Vitamin A · neutral · Instagram ↗
      Notes that Vitamin A is a fat-soluble vitamin that supports healthy skin cell turnover.
    • 15 Oct 2026 · Iodine · recommends · YouTube ↗
      Recommends taking sufficient iodine to ensure free T3 levels are right, which is important for the reverse calcium transport system.
    • 15 Oct 2026 · Magnesium · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · Magnesium · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Vitamin K · neutral · Facebook ↗
      Discusses vitamin K2, specifically the menaquinone forms, as crucial for arterial health and notes that it breaks down into MK-4 and MK-7.
  • Dr. Mark Hyman · Zinc · neutral
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that zinc is important for the body's repair crew, helping to heal damaged tissue, and a deficiency can lead to cuts and wounds taking longer to heal.
    • 4 Nov 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium breakthrough advanced ten from Biooptimizers, which is their most complete magnesium formula with 10 bioavailable forms and 550 milligrams of elemental magnesium, designed to support restful restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 4 Nov 2026 · Vitamin D · uses · YouTube ↗
      Consumes Zetopia's Atlantic salmon to get Vitamin D, particularly in the winter months, as it is one of the few foods that provides both Omega-3s and Vitamin D.
    • 1 Nov 2026 · Magnesium · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 29 Oct 2026 · Magnesium · neutral · YouTube ↗
      Explains that a lack of magnesium can cause muscles and nerves to malfunction, resulting in muscle weakness, twitching, and cramps.
    • 29 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions that the body makes vitamin D from sunlight exposure, and a deficiency can hinder calcium absorption, which is crucial for strong bones.
    • 29 Oct 2026 · Iron · neutral · YouTube ↗
      States that iron helps red blood cells carry oxygen, and a deficiency can make one feel like they are running on low power mode.
    • 26 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 21 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Iron · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
  • Thomas DeLauer · Zinc · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 6 Nov 2026 · Vitamin C · recommends · YouTube ↗
      Recommends whole food vitamin C, found in kiwi fruit, citrus, and bell peppers, to help clear uric acid by competing at kidney transporters, preventing reabsorption.
    • 5 Nov 2026 · Magnesium · recommends · YouTube ↗
      Recommends taking magnesium glycinate and threonate at night to act as a brake on the nervous system, block excitatory signaling, help wind down, and support serotonin and melatonin production for better sleep.
    • 5 Nov 2026 · Vitamin K · recommends · YouTube ↗
      Recommends taking Vitamin K2 with Vitamin D3 in the morning, along with morning fats, to ensure calcium is directed to the bones and not deposited in arteries or soft tissue.
    • 5 Nov 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking Vitamin D3 in the morning, between 6:00 and 10:00 a.m., to align with the body's natural metabolic activation phase and sunlight-triggered vitamin D production.
    • 4 Nov 2026 · Magnesium · neutral · YouTube ↗
      Mentions that magnesium glycinate also helps a lot with sleep.
    • 2 Nov 2026 · Magnesium · neutral · YouTube ↗
      Mentions that restless leg syndrome is often treated with magnesium, but states that the sensation is actually coming from three other issues.
    • 2 Nov 2026 · Iron · recommends · YouTube ↗
      Recommends giving any iron intervention a couple of months before deciding if it works, and suggests increasing heme iron through red meat or liver intake.
    • 28 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 24 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 23 Oct 2026 · Vitamin D · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
  • Dave Asprey · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 7 Nov 2026 · Vitamin K · recommends · YouTube ↗
      Explains that Vitamin K2 acts as a traffic cop for calcium, waving it into bones and away from arteries, and that grass-fed butter is one of the only foods with a real amount of K2.
    • 3 Nov 2026 · Magnesium · uses · Instagram ↗
      Looks at magnesium alongside protein to keep muscle for the long run.
    • 3 Nov 2026 · Magnesium · recommends · YouTube ↗
      Suggests adding magnesium to help keep potassium in the system longer, as they work hand in hand.
    • 3 Nov 2026 · Biotin · warns · YouTube ↗
      Mentions that most places put in extra biotin for hair growth, suggesting it's not always necessary or beneficial.
    • 3 Nov 2026 · Vitamin C · neutral · YouTube ↗
      Recounts a doctor telling him in his 20s that vitamin C would kill him.
    • 1 Nov 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 31 Oct 2026 · Magnesium · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · Magnesium · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 25 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 9 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
  • Siim Land · Zinc · recommends
    • 5 Aug 2026 · recommends · YouTube ↗
      States that deficiencies in nutrients such as zinc can impair normal immune regulation.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 25 Oct 2026 · Magnesium · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 24 Oct 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 14 Oct 2026 · Iron · neutral · Instagram ↗
      Mentions that iron is a mineral necessary for making collagen.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 9 Oct 2026 · Vitamin K · neutral · Instagram ↗
      Notes that Vitamin K2 helps activate proteins involved in bone mineralization and calcium regulation.
    • 8 Oct 2026 · Vitamin K · neutral · YouTube ↗
      Mentions that prunes contain vitamin K, which is a factor in their ability to help with bone density.
    • 7 Oct 2026 · Magnesium · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 7 Oct 2026 · Vitamin K · recommends · Instagram ↗
      Recommends Vitamin K2 for bone health and calcium metabolism, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · Magnesium · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
  • Bryan Johnson · Zinc · uses
    • 4 May 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 22 Oct 2026 · Vitamin K · uses · X ↗
      Takes 90 mcg of Vitamin K2 in the morning for general health.
    • 22 Oct 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 22 Oct 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Jul 2026 · Iron · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · Iron · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 3 Jul 2026 · Vitamin D · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · Vitamin K · uses · X ↗
      Takes 100 mcg of Vitamin K2 in the morning for longevity.
    • 4 May 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 4 May 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · Vitamin K · uses · X ↗
      He takes 100 mcg of Vitamin K2 in the morning for general health.
    • 2 May 2026 · Vitamin D · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
  • Peter Attia · Zinc · recommends
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 1 Jun 2026 · Magnesium · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · Magnesium · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 4 Jan 2026 · Vitamin D · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 17 Nov 2025 · Iodine · warns · Podcast ↗
      Discusses the dangers of supplementing with high levels of iodine.
    • 16 Nov 2025 · Iodine · warns · YouTube ↗
      Warns that high-dose iodine supplementation carries a risk of autoimmune thyroid disease, citing increased incidence in Japan due to higher dietary iodine intake.
    • 16 Nov 2025 · Vitamin D · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 15 Sep 2025 · Magnesium · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 6 Aug 2025 · Vitamin D · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 6 Aug 2025 · Vitamin A · neutral · YouTube ↗
      Notes that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin A for male mice.
    • 3 Aug 2025 · Vitamin D · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · Vitamin D · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 20 Jul 2025 · Vitamin A · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin A for male mice.
    • 10 Jul 2025 · Vitamin D · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.

RAL Summary

Members OnlyTier 2 for Thyroid Health

Iodine at the full studied dose clearly improves thyroid health in people low in iodine, zinc at three servings adds some pooled trial support, and 93% of 13,568 reviews are positive, which meets tier 2.

Take 3 servings a day (3 tablets) to match the dose that worked in the studies.

Where the evidence disagrees: 129 of the 235 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Endocrine system, Digestive system, Blood

Combine with: Selenium is often paired with iodine because both act on the same pathway: selenium based enzymes help convert thyroid hormone that is built with iodine. L-tyrosine is often paired with iodine because the body joins the two to make thyroid hormone. Copper is often paired with zinc because steady zinc intake can use copper up, so the two are commonly kept in balance.

Possible side effects: Iron and magnesium reduce meds absorption when taken at the same time, too much iodine can harm the thyroid, and biotin can distort thyroid blood tests. Some buyers found the fishy or orange smell nauseating, though many say it is easy on the stomach.

Supplement Facts

Vitamin A 770 mcg · Vitamin C 85 mg · Vitamin D3 25 mcg
Supplement Facts
Serving Size 1 Tablet(s)
Servings Per Container 90
Amount Per Serving% Daily Value
Vitamin A770 mcg
Vitamin C85 mg
Vitamin D325 mcg
Vitamin E15 mg
Vitamin K90 mcg
Thiamine1.4 mg
Riboflavin1.4 mg
Niacin18 mg
Vitamin B61.9 mg
Folate1,330 mcg DFE
Vitamin B125.2 mcg
Biotin30 mcg
Pantothenic Acid6 mg
Calcium250 mg
Iron27 mg
Iodine150 mcg
Magnesium45 mg
Zinc11 mg

Other ingredients: Cellulose Gel, modified Food Starch, Maltodextrin, hydrogenated Soybean Oil, Dibasic Calcium Phosphate, Croscarmellose Sodium, Hypromellose, Silicon Dioxide, Magnesium Stearate, Gelatin, Polyethylene Glycol.

Directions: 1 One Tablet per day Suggested Use: Adults, take 1 tablet daily with water and a meal.

Barcode (UPC) 031604014995 · Label source: NIH label database · Report a label change

Other sizes and barcodes: 250 Tablet(s), UPC 0 31604 01435 3 (on market); 300 Premium Tablet(s), UPC 0 31604 01736 1 (off market)

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The Nature Made Prenatal Multi label, 90 Tablet(s)
Prenatal Multi, 90 Tablet(s)

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Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.