Nature's Sunshine Free Amino Acids Review

Nature's Sunshine Free Amino Acids is listed on this page as a tablet supplement from the brand Nature's Sunshine. The page states that it has not yet been scored with a complete product TrustScore, and that SuppCo has insufficient data to evaluate it at this time. A Request score link is provided for users who want the product evaluated. The product is presented with a listed price of $49.95 and a price per serving of $1.67, with 30 servings per container. The serving size is 2 tablets. The page's suggested use reads: Take 2 tablets with a meal three times daily. The product page lists key active ingredients including Glycine, L-Alanine, L-Arginine, and L-Aspartic Acid. The nutrients section shows Glycine at 16mg, L-Alanine at 44mg, L-Arginine at 22mg, L-Aspartic Acid at 88mg, L-Carnitine at 100mg, and L-Cysteine at 21mg, with a link to see all 20 listed nutrients. The page describes the product as backed by ISO 17025-accredited third-party testing and NSF-certified manufacturing, while noting that product-specific testing is not currently verified by SuppCo. The inactive ingredients section lists vegetable magnesium stearate, hydrolyzed protein, silicon dioxide, cellulose, stearic acid, and silica, each with a function and a Safe rating on the page. Those functions include lubricant, emulsifier, humectant, emollient, anti-caking agent, anti-foaming agent, filler, and binder. The page also carries a standard disclaimer stating that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent any disease. No customer reviews or star ratings are shown on this page, and the product is listed as Unrated. Shoppers who want more detail on this product should review the full ingredient list and the disclaimer carefully before deciding. The page indicates that related products are loading in a separate section, but no related product details are included in the scraped text.

Product Focus: Muscle and StrengthAlso covers:MetabolismRanked among:Essential amino acids (EAA)
Tier ⓘ
Tier 4 · Rank 31
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 31 within Tier 4 for Muscle and Strength; 73 of 116 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
53 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
90% of 10
Biohacker Mentions
10 of 10
Cost per month
$450 at 3 servings

Study, Trial or Testing Result Summary

Members Only230 human studies · 111 improved

12 of these 230 human studies gave the ingredient by drip or injection, not by mouth.

230 human studies111 improved64 no effect109,280 people studied

Magnesium is the one ingredient here at or above a studied dose, and its evidence for muscle is weak. A pooled analysis of 14 trials found it did not meaningfully improve strength or power, though people low in magnesium might benefit [1]. In overweight women, 250 mg daily added no strength or lean mass [2]. Some smaller trials in low-magnesium groups or new strength trainers were positive [3][4]. L-carnitine, at 300 mg a day across three servings, is the ingredient with the best support. Even so, that is well below the 1 to 4 grams used in trials where older or ill people gained muscle [5][6]. In healthy older women, 1500 mg daily changed nothing [7]. Leucine, valine, isoleucine, lysine, arginine, cysteine and glycine are all far below the doses studied. Leucine helped mainly when paired with protein, not alone [8]. Glutamine alone did not add lean mass in athletes [9]. A blend of amino acids with carbohydrate added nothing to strength training in older men [10]. Most of the other amino acids have little or no human evidence for building muscle. Animal and cell studies are never counted.

See all 230 studies →Hide the studies

Review Totals and Summary

Members Only10 reviews · 90% positive
10 reviews · Nature's Sunshine via Caring Sunshine 10
90% positive0% neutral10% negative

Nature's Sunshine Free Amino Acids tablets have 10 ratings in total, all from one store (Caring Sunshine), and the themes below come from the written reviews that could be read on its page. That is a small number of ratings, and many of the written reviews are very short. No reviews of other forms such as gummies, capsules or powder were mentioned, so nothing had to be left out on that count. Buyers' praise is the main theme, and the feedback is overwhelmingly positive. The ratings histogram shows nine five-star ratings and one one-star rating. Several reviewers say they feel better after taking the tablets, and one says they feel much better and calls the quality and value great. Many use the words "great product" or simply say they love it, which accounts for most of the short review titles. One reviewer explains that amino acids are protein building blocks that keep the body structurally sound and support defense against various diseases, and says they love them. Another says they have been extremely satisfied with the herbs and will keep buying them, and several reviewers mention repeat purchase intent. Trust in the brand and recommendations from professionals come up repeatedly. One reviewer has used the product for around ten years and describes it as natural. Another says a doctor recommended Nature's Sunshine. A reviewer buying for a child undergoing chemotherapy reports that the pharmacy department at a children's hospital recommended these vitamins, which suggests professional confidence in the formula. Reviewers also praise the store itself. They cite fast shipping, being very happy with their purchases, and good customer service. One customer says they have bought from Caring Sunshine for close to eight years. On the complaints side, there are none about the product in the written text. The one-star rating in the histogram is not linked to any written comment on the page, so the reason for that low score cannot be determined. Several reviews consist only of a title such as "Free Amino Acids" with no body text, so they carry no detail beyond their star rating. As for who the tablets seem to suit, the feedback points to long-term users who want a natural supplement, people following a doctor's or pharmacist's recommendation, and a caregiver buying for a child in medical treatment. The reviews do not say anything about taste, tablet size or how easy the tablets are to swallow. On value, one reviewer calls it great, but no one gives price comparisons or dosing details. Overall, the picture is one of satisfaction with quality, value, outside recommendations and service, with some customers returning over many years. The caveat is that the written reviews are brief and short on specifics, and the single low rating remains unexplained.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

On L-carnitine, the main ingredient, nine of the ten panelists spoke, and they are split: four recommend it, three are neutral, one warns and one stopped taking it. Those who recommend it point to fertility and sperm quality, with one citing oral doses of 500 or 750 milligrams a day, while another suggests it for workouts to help move fat into cells and burn it, especially fasted before training. The neutral voices describe how it helps mitochondria make energy, and one notes it can be depleted. The caution is that one panelist warns against injecting it because of contamination risks, and another stopped because it converts to TMAO, a heart disease risk factor, and he saw no clear benefit for muscle or fat burning. Magnesium, glycine and leucine are smaller ingredients in this product, and the panel mostly takes magnesium and glycine at bedtime for sleep.

See all 10 biohackers →Hide the biohackers
  • Ben Greenfield · L-Carnitine · recommends
    • 19 Sep 2026 · recommends · YouTube ↗
      Recommends L-carnitine for male fertility, explaining that it helps shuttle fatty acids into mitochondria, assisting with beta-oxidation, and its concentration in sperm correlates with sperm motility.
    • 29 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Leucine · recommends · YouTube ↗
      Describes leucine as the 'ignition' that turns on the signal for muscle protein synthesis, and that a sufficient dose is needed to hit the dose response and then have other essential amino acids to maintain the signal.
    • 22 Oct 2026 · Magnesium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · Magnesium · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · Magnesium · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 19 Sep 2026 · neutral · Podcast ↗
      He mentions L-carnitine as a supplement with real human data behind it for male fertility.
    • 8 Sep 2026 · recommends · X ↗
      Recommends L-carnitine at 1-3 grams per day for at least 30 days pre-conception to improve mitochondrial function tied to sperm quality.
    • 3 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · Magnesium · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · Magnesium · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 15 Aug 2026 · Magnesium · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · Magnesium · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 9 Jul 2026 · Leucine · recommends · YouTube ↗
      States that leucine is the primary trigger for muscle protein synthesis and recommends an essential amino acid blend with about 40% leucine for maximum stimulation.
  • Dr. Rhonda Patrick · L-Carnitine · neutral
    • 7 Sep 2026 · neutral · YouTube ↗
      Discusses L-carnitine's role as a transporter for fatty acids into mitochondria for energy, its role in detoxifying metabolites, and its involvement in stabilizing cell membranes and ketone production. They mention studies showing it helps increase muscle mass and improve cognitive function in women, and meta-analyses showing reductions in body weight, waist size, and body fat in overweight and obese individuals.
    • 29 Oct 2026 · Magnesium · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · Magnesium · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 30 Sep 2026 · Leucine · recommends · YouTube ↗
      Notes that foods high in leucine are going to really support muscle protein synthesis.
    • 29 Sep 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · Magnesium · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 2 Sep 2026 · Magnesium · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 10 Aug 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
    • 10 Aug 2026 · Magnesium · recommends · X ↗
      Recommends considering magnesium to improve mood.
    • 31 Jul 2026 · Glutamine · uses · TikTok ↗
      Supplements with glutamine.
    • 28 Jul 2026 · Magnesium · recommends · Facebook ↗
      Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
    • 14 Jul 2026 · Glutamine · uses · X ↗
      Always packs Glutamine when traveling, taking a baseline of 5 g/day and increasing to 15-20 g/day when sleep-deprived or exposed to illness, as it is an important fuel source for immune function.
    • 29 Jun 2026 · Magnesium · neutral · Facebook ↗
      Mentions that kale delivers magnesium, a micronutrient many diets fall short on.
    • 26 Jun 2026 · Magnesium · recommends · Facebook ↗
      Recommends Magnesium, stating it is a cofactor for over 300 biological processes, including DNA repair, energy production, and sleep regulation.
  • Andrew Huberman · L-Carnitine · recommends
    • 27 Jul 2026 · recommends · YouTube ↗
      Andrew Huberman, based on discussions with fertility doctors, recommends L-carnitine for patients trying to increase fertility, egg quality, or sperm quality, noting it can be taken orally in higher dosages like 500 or 750 milligrams a day, or via injectable form.
    • 22 Oct 2026 · Magnesium · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 7 Aug 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 6 Aug 2026 · Tryptophan · recommends · Podcast ↗
      Recommends tryptophan-rich foods to improve serotonin and mood.
    • 6 Aug 2026 · Tryptophan · recommends · YouTube ↗
      Notes that tryptophan is an amino acid precursor to serotonin synthesis and that many foods enriched in tryptophan can lead to net increases in serotonin, impacting feelings of well-being.
    • 27 Jul 2026 · Magnesium · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · Magnesium · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 20 Jul 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 13 Jul 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 13 Jul 2026 · Glycine · uses · X ↗
      Takes 2 grams of Double Wood Glycine before bed for sleep.
    • 12 Jul 2026 · Magnesium · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 12 Jul 2026 · Glycine · uses · X ↗
      He takes 2 grams of Glycine before bed for sleep.
  • Dave Asprey · L-Carnitine · recommends
    • 16 Dec 2025 · recommends · YouTube ↗
      States that L-Carnitine shows changes happening in fertility.
    • 31 Oct 2026 · Magnesium · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · Magnesium · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 27 Sep 2026 · Magnesium · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · Magnesium · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 5 Sep 2026 · Glycine · recommends · YouTube ↗
      Recommends GlyNAC (glycine and NAC together) as very affordable amino acids that he would bet his coffee on if he had to choose just one thing for longevity, as they help the body make glutathione, the master antioxidant.
    • 3 Sep 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 29 Aug 2026 · Magnesium · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
    • 15 Aug 2026 · Magnesium · recommends · YouTube ↗
      Dave Asprey recommends adding 300 or 400 mg of magnesium glycinate before bed to improve deep sleep quality, support growth hormone release, and burn visceral fat while asleep.
    • 28 Jul 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 25 Jul 2026 · Tryptophan · recommends · YouTube ↗
      Recommends tryptophan, an amino acid from high-quality complete animal protein sources like turkey, as a raw material for NAD+ production.
    • 16 Jul 2026 · Glycine · warns · Podcast ↗
      Dave discusses safe upper limits for glycine before it starts working against you, mentioning oxalate crystal and Parkinson's-like risks of overdoing it.
  • Dr. Mark Hyman · L-Carnitine · neutral
    • 25 Jun 2025 · neutral · YouTube ↗
      Mentions that supplementing with L-carnitine can make mitochondria more efficient.
    • 1 Nov 2026 · Magnesium · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 21 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · Magnesium · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 30 Sep 2026 · Magnesium · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 22 Sep 2026 · Magnesium · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 16 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
    • 9 Sep 2026 · Magnesium · uses · YouTube ↗
      Has recommended Magnesium Breakthrough from Bio Optimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 2 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from Bio Optimizers, which contains 10 bioavailable forms of magnesium, as it plays a critical role in sleep recovery, stress regulation, and muscle function, and has become part of his evening routine, especially during periods of travel, training, and higher stress.
    • 2 Sep 2026 · Glutamine · neutral · YouTube ↗
      Mentions glutamine as something that might be helpful for gut repair.
    • 10 Aug 2026 · Leucine · recommends · YouTube ↗
      Dr. Mark Hyman, agreeing with the guest, highlights leucine as a primary amino acid important for muscle protein synthesis.
    • 7 Aug 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
  • Thomas DeLauer · L-Carnitine · recommends
    • 6 Jun 2025 · recommends · YouTube ↗
      Recommends L-carnitine, especially if working out, to help shuttle fat into the cell better and improve fat oxidation, particularly in a fasted state before a workout.
    • 28 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 27 Oct 2026 · Glycine · neutral · YouTube ↗
      Explains that glycine is critical for collagen synthesis, which supports the intestinal wall, and deficiency can slow down the repair process.
    • 27 Oct 2026 · Glutamine · neutral · YouTube ↗
      States that glutamine is the primary fuel source for intestinal cells, and its availability is crucial for the integrity of the gut barrier.
    • 26 Oct 2026 · Glycine · recommends · YouTube ↗
      Explains that the body needs roughly 10g more of glycine per day than a typical modern diet provides, and that this deficit can lead to issues with creatine production, connective tissue repair, and sleep. He recommends increasing glycine intake.
    • 24 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 19 Oct 2026 · Leucine · recommends · YouTube ↗
      Identifies leucine as the primary trigger for the mtorc1 pathway, which is the master switch for muscle protein synthesis, and recommends 2 to 3 grams per meal for those under 40, and 3 to 4 grams for those over 40.
    • 16 Oct 2026 · Glutamine · recommends · YouTube ↗
      Recommends supplementing with glutamine for a calming effect, especially when experiencing high stress, injury, illness, or increased training volume, as it acts as a precursor to GABA and helps the body produce more of it.
    • 14 Oct 2026 · Glycine · uses · YouTube ↗
      Shifts towards glycine when cutting to keep their nervous system calm through the deficit.
    • 14 Oct 2026 · Glutamine · uses · YouTube ↗
      Loads up on extra glutamine during muscle building phases.
    • 12 Oct 2026 · Glycine · neutral · YouTube ↗
      Explains that glycine is a critical amino acid for glutathione production, and the body often has a significant shortage of it, with creatine synthesis consuming a large amount of available glycine.
    • 8 Oct 2026 · Magnesium · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
  • Dr. Eric Berg · L-Carnitine · neutral
    • 31 May 2024 · neutral · YouTube ↗
      Mentions L-carnitine as another nutrient that can be depleted, similar to co-enzyme Q10.
    • 30 Oct 2026 · Magnesium · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 25 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · Magnesium · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
    • 24 Oct 2026 · Magnesium · recommends · Instagram ↗
      Dr. Eric Berg suggests that magnesium could help support deeper, more restful sleep.
    • 24 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Glycinate, noting that the combination of magnesium and glycine is helpful for connective tissue, sleep, and reducing stress.
    • 24 Oct 2026 · Glycine · recommends · YouTube ↗
      Recommends Glycine as a cofactor, especially for collagen.
    • 23 Oct 2026 · Magnesium · recommends · Instagram ↗
      Recommends taking magnesium 90 minutes to 2 hours before bedtime to support better sleep.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Suggests that magnesium glycinate can help support the missing 'break pads' on the nervous system, which contribute to constant pain.
    • 23 Oct 2026 · L-Lysine · recommends · YouTube ↗
      Recommends L-lysine because it competes with L-arginine, which the virus needs to reproduce, thus blocking the virus from getting arginine and starving it off.
    • 22 Oct 2026 · Magnesium · recommends · Podcast ↗
      Taking 400 mg of magnesium glycinate daily may also help support brain health during menopause.
    • 22 Oct 2026 · Leucine · recommends · Podcast ↗
      The amino acid leucine is important for muscle growth, but getting sufficient protein is just as essential for maintaining muscle mass.
    • 21 Oct 2026 · Magnesium · warns · YouTube ↗
      Warns against magnesium oxide because it is poorly absorbed, with only about 4% absorption, and can cause diarrhea, despite being commonly used in research and supplements due to its low cost.
  • Peter Attia · L-Carnitine · warns
    • 3 Mar 2024 · warns · YouTube ↗
      Discusses L-carnitine, noting that people inject it for fat loss and to get more out of testosterone input, but warns against injecting it due to potential contamination from homebrewing or even compounding pharmacies, which have had issues leading to deaths.
    • 1 Jun 2026 · Magnesium · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 1 Jun 2026 · Glycine · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · Magnesium · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 26 Sep 2025 · Threonine · neutral · YouTube ↗
      Mentions that threonine is important for mucin production in the gut.
    • 26 Sep 2025 · Leucine · recommends · YouTube ↗
      States that leucine is critical for muscle protein synthesis and recommends around 8 or 9 grams a day for optimal muscle health.
    • 21 Sep 2025 · Leucine · recommends · YouTube ↗
      Recommends two to three grams of leucine a day for muscle health, with optimal health probably around eight or nine grams.
    • 15 Sep 2025 · Magnesium · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 20 Jul 2025 · Glycine · neutral · YouTube ↗
      Mentions that they also see positive effects of glycine, among other things.
    • 9 Jul 2025 · Magnesium · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · Magnesium · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 30 Aug 2024 · Leucine · neutral · YouTube ↗
      Recounts a story where a vegan doctor chastised him for suggesting ingesting five grams of leucine during a workout due to its negative effect on mTOR and potential link to cancer, which Peter Attia found amusing.
    • 7 Jul 2024 · Magnesium · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · Magnesium · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
  • Siim Land · L-Carnitine · stopped
    • 12 Apr 2023 · stopped · YouTube ↗
      Stopped taking L-Carnitine because it converts to TMAO, a cardiovascular disease risk factor, and he hasn't noticed significant benefits for muscle growth or fat oxidation, preferring not to gamble with the risk given his family history of cardiovascular disease.
    • 31 Oct 2026 · Glycine · recommends · Instagram ↗
      Suggests that a higher glycine to methionine ratio appears to preferentially target visceral fat and improve insulin sensitivity.
    • 29 Oct 2026 · Glycine · recommends · Instagram ↗
      Recommends pairing NAC with glycine to support antioxidant activity in your sleep.
    • 26 Oct 2026 · Glycine · recommends · YouTube ↗
      Believes glycine is the best longevity supplement and encourages viewers to learn more about its longevity benefits.
    • 25 Oct 2026 · Glycine · recommends · Instagram ↗
      States that Glycine can be a useful addition for some people for sleep.
    • 25 Oct 2026 · Magnesium · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 21 Oct 2026 · Glycine · uses · YouTube ↗
      Increased his glycine supplementation to 10g a day, noting that it balances methionine and improves blood sugar and glycation.
    • 19 Oct 2026 · Glycine · uses · YouTube ↗
      Personally uses glycine for its health benefits, including glutathione, blood sugar glycation, and potentially sleep, and notes that it appears to have some autophagy benefits by increasing autophagy through its role in methionine metabolism.
    • 19 Oct 2026 · Methionine · recommends · YouTube ↗
      Recommends keeping methionine intake slightly lower to support autophagy.
    • 14 Oct 2026 · Glycine · neutral · Instagram ↗
      Notes that glycine is one of the most important building blocks for collagen synthesis, making up 30% of collagen, and that 12g of glycine a day is needed for collagen turnover.
    • 13 Oct 2026 · Glycine · uses · Instagram ↗
      Increased his glycine intake as part of an experimental amino acid strategy.
    • 13 Oct 2026 · Glycine · neutral · X ↗
      Retweeted a study stating that 3 g of glycine before bed helped people fall asleep faster and reach deep sleep sooner.
    • 13 Oct 2026 · Methionine · uses · Instagram ↗
      Lowered his methionine intake as part of an amino acid strategy.
    • 12 Oct 2026 · Glycine · uses · YouTube ↗
      Takes around 3 to 5 grams of glycine before bed, often mixed with chamomile tea, as human trials have found it can improve subjective sleep quality and shorten the time to fall asleep and enter deep sleep.
  • Bryan Johnson · Glycine · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 22 Oct 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 15 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 4 May 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 2 g of Glycine before bed for sleep.
    • 2 May 2026 · Magnesium · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 21 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 15 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 14 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.

RAL Summary

Members OnlyTier 4 for Muscle and Strength

L-carnitine has supportive human trials, but this product gives it below the studied doses and most other ingredients are trace or unproven. With only 10 ratings, the evidence stays emerging.

Take 3 servings a day (6 tablets) to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 64 of the 230 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Muscular system, Metabolic system

Combine with: For its primary purpose of muscle building and recovery, pair it with creatine monohydrate, vitamin D3, magnesium, and omega-3 fatty acids, along with adequate dietary protein. If the goal is blood flow, add L-arginine or L-citrulline (nitric oxide precursors), beetroot extract (dietary nitrates), omega-3 fish oil, and CoQ10 for vascular and cardiac support. Nattokinase, vitamin K2, and magnesium can also support healthy circulation. Consult a healthcare provider before combining these if you take meds or meds.

Possible side effects: No major side effects reported in the studies given. Note that the listing says it contains whey protein from milk.

Supplement Facts

Magnesium 106 mg · L-Glutamine 140 mg · L-Carnitine 100 mg
Supplement Facts
Serving Size 2 Tablet(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Magnesium106 mg
L-Glutamine140 mg†
L-Carnitine100 mg†
L-Leucine100 mg†
L-Lysine90 mg†
L-Aspartic Acid88 mg†
L-Valine70 mg†
L-Isoleucine56 mg†
L-Phenylalanine56 mg†
L-Threonine56 mg†
L-Proline45 mg†
L-Alanine44 mg†
L-Serine41 mg†
L-Tyrosine30 mg†
L-Methionine29 mg†
L-Arginine22 mg†
L-Cysteine21 mg†
Glycine16 mg†
L-Histidine16 mg†
L-Tryptophan14 mg†
† Daily Value not established.

Other ingredients: Hydrolyzed Whey Protein, Cellulose, Stearic Acid, Silicon Dioxide, Vegetable Magnesium Stearate.

Directions: Recommended Use: Take 2 tablets witha meal three times daily.

Barcode (UPC) 099904036642 · Label source: NIH label database · Report a label change

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Our articles on this subject

Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.