Nutricost L-Citrulline Powder Review
Nutricost L-Citrulline Powder is a dietary supplement designed to support athletic performance, increase blood flow, and promote cardiovascular health. It provides pure L-Citrulline to help the body produce nitric oxide.
We don’t sell supplements. We help you make decisions and get the best price.
Lowest prices
We may earn a commission from some store links. How we choose.
Lowest cost per month first, in stock, at 1 serving a day. Checked Nov 8.
- VitacostLowest$21.95 a bottle$3.29/moBuy at Vitacost (opens in a new tab)
- Target$23.99 a bottle$3.60/moBuy at Target (opens in a new tab)
- AmazonPrice at AmazonCheck price at Amazon (opens in a new tab)
Also at: Nutricost · iHerb · Walmart. Some links earn us a commission; price comes first, and a commission only decides the order of prices within 2%. As an Amazon Associate we earn from qualifying purchases.
Study, Trial or Testing Result Summary
Members Only8 human studies · 7 improved
This powder gives 3 grams of citrulline per serving, which is more than the 1.5 grams that worked in the main study. In that controlled trial of 24 men with mild erection problems, 1.5 grams of citrulline daily for one month brought erection hardness back to normal in 12 men, or 50 percent, compared with 2 men, or about 8 percent, on placebo [1]. Most other studies tested citrulline mixed with other ingredients that this product does not contain, so their results may not apply directly. A 3 month trial of 164 men found a citrulline-containing mixture improved erection scores, working best alongside a daily erection drug [2]. A trial of 50 men found pine bark extract with arginine and citrulline restored erectile function within one month [3]. Two small trials of 20 men each, using lower amounts of citrulline with resveratrol and other ingredients, improved sexual function scores in men already taking erection drugs [4][5], though one found erection hardness itself did not change much [5]. In a review of men having prostate surgery, 56 percent of those who started citrulline with an erection drug before surgery regained function within a year, versus 24 percent who started after [6]. Animal and cell studies are never counted.
See all 8 studies →Hide the studies
- In 164 men with mild to moderate erectile dysfunction, a daily citrulline-containing mixture taken for 3 months improved erection scores (+4.1 points) and worked best combined with daily a med (+7.4 points vs +5.1 for a med alone).Read the study on PubMed (38731094) →
- In 50 men with moderate erectile dysfunction, one month of a combination of pine bark extract, roburins, and the amino acids arginine and citrulline restored erectile function to normal compared with placebo.Improvement of erectile function by a combination of French maritime pine bark and roburins with aminoacids.
- In 20 men (13 finished) with erectile dysfunction despite erection drugs, 800 mg citrulline plus 300 mg resveratrol daily for one month raised the sexual health score from about 8.3 to 11.0 versus placebo, though erection hardness did not change significantly.Oral L-citrulline and Transresveratrol Supplementation Improves Erectile Function in Men With Phosphodiesterase 5 Inhibi…
- In 20 men with sexual dysfunction who kept using erection drugs, a drink with 800 mg citrulline plus testofen, resveratrol and caffeine for 14 days improved desire, erection, orgasm, ejaculation and satisfaction scores versus placebo.Oral Testofen, L-Citrulline, Resveratrol, and Caffeine Supplement Drink Improves Sexual Function in Men with Phosphodies…
- In 24 men with mild erectile dysfunction, 1.5 g of citrulline daily for one month improved erection hardness to normal in 12 men (50%) versus 2 (8.3%) on placebo.Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction.
- In an uncontrolled 3-month safety pilot of middle-aged men taking 1,600 mg of L-citrulline daily with other plant ingredients, about half reported a significant improvement in erection, with only mild side effects in 5 men.Safety and efficacy of daily Revactin® in men with erectile dysfunction: a 3-month pilot study.
- In a retrospective review of 581 men who took L-citrulline and a med around prostate removal surgery, only 2.9% developed Peyronie's disease, but return of erections did not differ between those who did and did not develop it.Potential primary prevention of Peyronie's disease post prostatectomy?-retrospective analysis of peri-operative multi-mo…
- In a retrospective review of 131 men having prostate removal surgery, 56% of those who started L-citrulline and a med two weeks before surgery regained erectile function within 12 months, compared with 24% of men who started after surgery.Efficacy of a preprostatectomy multi-modal penile rehabilitation regimen on recovery of postoperative erectile function.
Review Totals and Summary
Members Only4,224 reviews · 70% positive
Nutricost L-Citrulline Powder consistently receives strong feedback from users across various platforms, with a majority voicing positive experiences. Many reviewers highlight its perceived effectiveness, especially for those using it in their workout routines. Frequent mentions include improved circulation, enhanced endurance, and better pumps during exercise sessions. Several users on Amazon and Nutricost’s own site note that the powder is easy to mix and dissolves well in water or other liquids. Users who appreciate flavorless supplements particularly like that Nutricost L-Citrulline Powder doesn’t have a strong taste, making it easy to incorporate into various drinks without altering their flavor. Some customers also praise the product for offering good value for the price, mentioning that the serving size and quantity last a reasonable amount of time compared to competitors. While the overall sentiment is positive, there is a noticeable group of neutral reviews that reflect more middle-of-the-road impressions. Some users state that while the product is easy to use, they didn’t notice significant changes or dramatic effects after regular use. This theme appears among those who are newer to supplements or unsure what exact results to look for. A few others mention that the packaging could be improved, with occasional complaints about the included scoop either being missing or hard to find in the powder. There are also some remarks about the powder clumping slightly if not stirred or shaken well, though these don’t appear to be major deterrents. Negative feedback, while less common, focuses mainly on concerns related to taste and solubility, usually from users who are more sensitive to texture or expected a completely flavorless profile but detected a slight aftertaste. Some reviewers also express dissatisfaction with either the effectiveness or quality, especially among those who did not feel any noticeable difference in their fitness performance or overall well-being. A handful of users raise issues about potential batch inconsistencies or receiving products with damaged seals, though these experiences are relatively rare compared to the number of positive reviews. In summary, most people who purchase Nutricost L-Citrulline Powder are satisfied with its ease of use, effectiveness, and value, especially for athletic and fitness purposes. Neutral users often don’t see major changes but acknowledge the product’s simplicity and practicality. Negative reviews are infrequent and generally mention solvable issues or personal preferences. Overall, Nutricost L-Citrulline Powder is widely considered a reliable supplement for those seeking to support their exercise routines, though like any supplement, individual results and experiences vary.
Biohacker Summary
Members Only6 of 10 recommend it
Most of the panel leans toward recommending citrulline: five of the ten have it as their latest position, three are neutral, one warns, and none of the ten says outright to avoid it. The main reasons are better blood flow through more nitric oxide, a stronger pump and less fatigue during workouts, easier recovery, and help with erectile problems. Panelists mention the plain L-citrulline form and citrulline malate, and doses range from 1.5 grams a day for mild erectile problems, to 3 to 6 grams, 5 grams every morning, and 6 to 8 grams before training. It is often taken before a workout or about 30 minutes before a sauna, and it is paired with arginine, vitamin C, beetroot, protein powders, or leucine. Two panelists said they stopped, one because he noticed no real difference in blood flow and one because he had already tested most supplements, and one panelist warns it can bring on cold sores and canker sores, can affect blood pressure, and can feel too strong for some people.
See all 9 biohackers →Hide the biohackers
Dave Asprey · Citrulline · recommends
- Notes that a 2011 trial found 1.5 g of L-citrulline daily restored normal erectile function in 50% of men with mild ED, and states that it's worth knowing about for mild ED.
- Dave Asprey recommends Joy Mode, an electrolyte packet for sexual performance, to be taken one packet about 45 minutes before sex, as it contains clinical doses of L-citrulline, arginine nitrate, ginseng, and vitamin C to increase nitric oxide levels.
- Suggests L-citrulline as an amino acid to consider for performance, noting that guys who work out like it.
- Has tried citrulline over the years but did not notice a significant difference in blood flow.
- Dave Asprey says that the case for citrulline is non-existent.
- Warns that taking excess L-arginine or L-citrulline would likely have a limited impact on N.O. production.
Siim Land · Citrulline · neutral
- States that L-citrulline can raise arginine availability and support the conventional enzymatic pathway for nitric oxide production, which does not depend on mouth bacteria.
- Places Citrulline in the 'good' tier because this amino acid helps with nitric oxide production, thereby improving blood flow.
- Suggests that citrulline, taken before a workout to increase blood flow, might also promote some of the benefits from the sauna.
- Used to take citrulline in the past but no longer does, as he has already tested most supplements.
- Places Citrulline in the 'good tier' because this amino acid helps with nitric oxide production and blood flow.
- Discusses Citrulline as a supplement.
- Notes that citrulline is popular in evidence-based circles but lacks compelling research support.
- Mentions that one could supplement citrulline directly for better workout performance.
- Recommends Citrulline before workouts to promote blood flow, which leads to better workouts and physical performance.
- Notes that citrulline helps with the pump.
Thomas DeLauer · Citrulline · recommends
- Explains that citrulline, found in watermelon, is converted to arginine, which feeds nitric oxide synthase, amplifying one of the contraction signals that drives glucose into muscle cells, and also helps clear ammonia during exercise, preserving muscle function and accelerating recovery.
- Highlights L-citrulline, found richly in watermelon, as an amino acid that feeds into nitric oxide, improving performance, recovery, and reducing muscle soreness by clearing metabolic waste and supporting the urea cycle.
- Recommends L-citrulline as it converts to arginine, a precursor to nitric oxide, is calorie-free, doesn't break a fast, and increases plasma nitrite levels.
- Believes there is a lot of benefit to pump products like citrulline for hypertrophy training.
- Mentions citrulline malate as an honorable mention for building muscle, noting it has evidence behind it.
- Recommends Citrulline Malate to increase blood flow, comparing its effects to Arginine.
- Recommends L-Citrulline to improve tissue quality and enhance power output during workouts.
- Recommends L-Citrulline for enhancing tissue quality and muscle performance.
- Includes citrulline in his tier two supplements, noting good evidence for performance, especially at a dose of 6 grams of citrulline malate.
- Notes that watermelon contains citrulline, which increases blood flow, contributing to its powerful hydration effect.
Ben Greenfield · Citrulline · recommends
- Recommends taking citrulline, a pre-workout that vasodilates, about 30 minutes before a sauna session to induce more sweating and aid in detoxification.
- Recommends L-citrulline, typically 3 to 6 grams, as an aid for sexual performance and to combat erectile dysfunction.
- Dave Pascoe mixes up a concoction of different protein powders, leucine, and L-citrulline as a pre-workout drink.
- Mentions citrulline as a supplement that can increase blood flow for pre-workout.
- Will explore L-citrulline as a natural libido enhancer.
- Ben Greenfield recommends L-citrulline, an amino acid found in products like JOYMODE, for boosting nitric oxide production, improving blood flow to genital tissues, and enhancing sexual performance and satisfaction.
- Mixes L-citrulline into a concoction of protein powders before his workout.
- Has used JOYMODE, a sexual performance booster containing arginine, citrulline, and vitamin C, and finds it works pretty well, though it can be a central nervous system stimulant if taken too close to bedtime.
- Ben likes it when he takes a pre-workout like citrulline and gets a wonderful rush in energy and blood flow.
- Ben says his secret weapon for withstanding the cold is a higher dose niacin or niacinamide, combined with a blood flow precursor like arginine or citrulline, and T2 thyroid hormone.
Dr. Rhonda Patrick · Citrulline · neutral
- Supplements like beetroot juice or citrulline can help close that gap, providing both systemic and cerebral benefits through enhanced vascular function.
- Recommends citrulline as a blood flow enhancer that boosts nitric oxide, opens up blood vessels, and can improve how one feels during endurance or high-rep sessions, also sharpening mental clarity.
- Discusses citrulline as a blood flow enhancer that can improve performance, noting it has a very pronounced stimulant effect and can cause a physical pump, but can be too powerful for some people.
- Discusses whether nitric oxide boosters like beetroot, citrulline, and arginine work.
- States that citrulline may have some benefits for fatigue resistance, especially at a dose of 6 grams.
Dr. Mark Hyman · Citrulline · neutral
- Mentions that athletic cocktails include amino acids like citrulline to help with recovery and improve physical performance.
- States that his arginine powder also contains citrulline, which he takes every single morning.
- Has been taking a powder formulation that includes citrulline, along with arginine and vitamin C, since July 2003. He takes 5 grams every morning for heart health.
- Has been taking Niteworks, a powder containing 5 grams of arginine, citrulline, and vitamin C, every morning since July 2003 for heart health.
Peter Attia · Citrulline · recommends
- Recommends citrulline malate, stating it increases blood nitrate levels more than arginine due to better bioavailability, and can enhance performance and potentially stimulate mtor for hypertrophy.
- Recommends citrulline malate or citrulline specifically, noting it increases blood nitrate levels more than arginine and is included in his pre-workout product, with a recommended dose of 6 to 8 grams.
Andrew Huberman · Citrulline · warns
- Andrew Huberman warns that L-citrulline can cause vicious cold sores and canker sores, and not everyone tolerates it well.
- Mentions a new meta-analysis showing that citrulline malate can reduce fatigue, increase time to fatigue, and may have small recovery benefits.
- Notes that a med works similarly to citrulline or other pump products in pre-workout supplements.
- Notes that citrulline can improve performance for long bouts of exercise due to vasodilation, but warns that it can increase the likelihood of herpes cold sore outbreaks.
- Suggests L-Citrulline is better for increasing Arginine than Arginine itself, and cautions about its effect on blood pressure.
- Notes a caution about Arginine and Citrulline in relation to cold sores.
- Mentions L-Citrulline as a supplement for improving sexual and urological health.
- Non-stimulant pre-workout alternatives, such as citrulline, can enhance performance by increasing vasodilation without the downsides of stimulants.
Dr. Eric Berg · Citrulline · recommends
- Recommends citrulline, an amino acid precursor for nitric oxide, to help increase nitric oxide and improve erectile dysfunction.
RAL Summary
Members OnlyTier 3 for Sexual Health for Men
Placed in this tier because 70 percent of its 4234 reviews are positive and human studies support citrulline, including a controlled trial where 1.5 grams daily restored normal erection hardness in half of men with mild erection problems [1].
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system, Reproductive system
Combine with: Not compulsory. Can be taken with water or added to pre-workout drinks.
Possible side effects: No major side effects reported.
Supplement Facts
L-Citrulline 3 g
| L-Citrulline | 3 g | † |
Other ingredients: Other ingredients: None.
Directions: SUGGESTED USE: As a dietary supplement, mix 1 scoop daily with 6-10 oz of water or as directed by your healthcare professional.
Barcode (UPC) 810014679327 · Label source: Amazon · Report a label change
Show entire label
More sexual health for men products
Members OnlyThe highest ranked for the same goal
Read more
Our articles on this subject
- How to Lower Blood Pressure NaturallyArticle · Jun 27, 2026
- Layne Norton's Supplement Stack, Reviewed: The Three-Item Core, What He Refuses to Take, and What the Evidence SupportsArticle · Oct 2, 2026
Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
Privacy policyConsumer health dataAffiliate disclosureTermsDo Not Sell or Share My Personal InformationCookie settings