Organixx Magnesium 7 Review

Organixx Magnesium 7 Complex, Sleep & Muscle Support, 60 Caps is a capsule supplement that the listing describes as a unique blend of seven forms of magnesium in one convenient daily capsule. The seven forms named on the page are glycinate, citrate, malate, taurate, chelate, aspartate, and orotate, which the listing says are designed for broad-spectrum support and easy absorption. The page states that each serving delivers all of these magnesium types in chelated forms, so that the body can most easily assimilate the mineral and send it where it needs it most. The listing presents this as 100% chelated magnesium for superior absorption. The product is positioned for relaxation and muscle function. According to the page, magnesium plays a key role in normal muscle function and relaxation, helping support muscle comfort after daily activity and a relaxed, balanced mood. A separate bullet says magnesium also contributes to healthy heart, bone, and muscle function and helps support relaxation as part of an evening wind-down routine. Usage is stated on the page: take 2 capsules with your evening meal. The item highlight reads 7-type magnesium with glycinate, Vitamin B6 and Manganese Citrate, supporting relaxation, restful sleep, muscle and heart health. The product benefits field lists magnesium capsules for sleep support, muscle recovery, with vitamin B6 and manganese citrate and glycinate. Quality claims on the page include that Magnesium 7 does not contain magnesium oxide, chloride, hydroxide, sulfate, or stearate, that it is 100% non-GMO, and that it has no stearates, fillers, additives, artificial flavors, preservatives, colors, yeast, soy, sodium, or starch. The diet type is listed as vegan, the flavor as unflavored, and the item form as capsule. The sold-by seller is Organixx, shipped from Amazon, with a unit count of 60 count and an item weight of 2.08 ounces. The listing is marked as a small business brand. Subscribe and Save pricing is offered at $34.15 with 10 percent savings, and $32.26 with 15 percent savings on repeat deliveries.

Product Focus: Stress and CalmAlso covers:BrainHormonesDigestionMuscles
Tier ⓘ
Tier 3 · Rank 1
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 1 within Tier 3 for Stress and Calm; 11 of 35 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
73 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
91% of 10,113
Biohacker Mentions
9 of 10
Cost per month
$38

Study, Trial or Testing Result Summary

Members Only53 human studies · 22 improved

5 of these 53 human studies gave the ingredient by drip, not by mouth.

53 human studies22 improved16 no effect22,533 people studied

Magnesium is the main ingredient here, at a full dose of 500 mg a day, which is more than the daily recommended limit; members can take less. The evidence that magnesium calms stress or anxiety is suggestive but weak. In 126 adults with mild to moderate depression, 248 mg a day for 6 weeks improved anxiety scores more than no treatment, but there was no placebo group [1]. In 264 stressed adults with low magnesium, 300 mg a day for 8 weeks cut stress scores by about 42 percent, again without a placebo group [2]. A placebo-controlled trial in 49 adults found 350 mg a day for 24 weeks lowered the stress hormone cortisol [3]. A pooled analysis of 52 trials found only a small effect of magnesium on depression scores [4]. Other placebo-controlled trials found no clear benefit for sleep in older adults [5] or for anxiety in women with osteoporosis [6]. Vitamin B6 is present at only 2 mg, far below the 30 mg or more used in studies, so it should not be expected to add a benefit [2][7]. Manganese has no human studies for this goal. Animal and cell studies are never counted.

See all 53 studies →Hide the studies

Review Totals and Summary

Members Only10,113 reviews · 91% positive
10,113 reviews · Amazon 3,740 · Organixx 2,537 · Shop.organixx 2,536 · Walmart 1,300
91% positive4% neutral5% negative

Organixx Magnesium 7 capsules get strongly positive feedback, with about 7,577 ratings across the stores that sell it. Most buyers praise it for sleep and night-time cramps, and the main drawbacks are stomach upset for a few people and price. **What buyers say it did for them:** Sleep comes up most. Buyers say they fall asleep faster and stay asleep longer. One says it is "more effective than any other natural sleep remedies," and another reports "falling asleep, faster and staying asleep longer." Night-time cramps are the next most common benefit. One reviewer who had leg cramps 2-10 times a night wrote "Since starting Mag7, they're gone!" Some also mention calmer mood and less anxiety ("lessening my anxiety"), better morning energy, more regular bowel movements, and relief from aches and joint pain. One long-term user says "I can feel the difference when I don't take it." **What buyers complain about:** The main complaint is digestive. One 1-star reviewer says it "gives me diarrhea" and could not tolerate it even after cutting the dose to one pill a day or less often. A 4-star reviewer found two capsules at once "too strong, causing diarrhea," and now takes one with breakfast and one at bedtime. Other buyers report no bowel problems at all. One reviewer wished the blend included threonate, though still recommended it as a first choice. **Taste, smell, pill size or form:** Reviewers don't say anything about taste, smell or capsule size. The page summaries note praise for the blend of several magnesium forms, and one buyer calls it "highly absorbable." **Value for money:** Price is the one recurring caveat in the store summary, which describes the product as affordable in some ways but pricey at times. One buyer who tried a free sample calls it "Worth the investment." Several describe it as a household staple they never want to run out of. **Who it seems to suit and who it did not:** It seems to suit people who want help with sleep, night-time cramps or general magnesium support, and especially people who have tried other magnesium products without success. One reviewer says they have "never had an oral magnesium product work so well," and others say none compared. Many are long-term repeat buyers, and couples often take it together. It did not suit the reviewer whose digestion could not handle it at any dose. Those with sensitive digestion may want to note that one buyer needed to split the dose. **Pages and forms left out:** The eBay page had no product ratings or written reviews, only seller feedback about shipping and packaging, so it adds nothing about the capsules. No reviews of other forms such as gummies or powder are included here.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Seven of the ten panelists recommend magnesium and the rest use it or stay neutral, so the panel leans clearly in favor. Sleep is the most common reason, along with muscle cramps and recovery, blood pressure, bone health and vitamin D function. The panel prefers glycinate for absorption and threonate for sleep and the brain, and four of them take 400 mg of threonate before bed. Others suggest 300 to 500 mg a day from food and supplements, with a few aiming higher, and some pair it with electrolytes like sodium and potassium or with vitamin D and B1. One panelist says magnesium does not fix waking up during the night, and manganese is only a smaller ingredient in this product that one panelist mentioned in passing.

See all 10 biohackers →Hide the biohackers
  • Dr. Rhonda Patrick · Magnesium · recommends
    • 8 Nov 2026 · recommends · Instagram ↗
      Explains that magnesium helps the body activate and metabolize vitamin D, and that magnesium intake has been associated with lower odds of vitamin D deficiency and insufficiency.
    • 6 Nov 2026 · neutral · Instagram ↗
      Mentions that getting too little magnesium may play a role in declining testosterone levels.
    • 3 Nov 2026 · recommends · X ↗
      Recommends getting enough magnesium, around 300–400 mg daily from diet and supplements, as it is an essential cofactor for vitamin D metabolism. Magnesium glycinate is a good form.
    • 1 Nov 2026 · neutral · YouTube ↗
      Mentions magnesium as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 31 Oct 2026 · neutral · YouTube ↗
      Explains that magnesium helps control blood pressure by boosting the production of substances that relax blood vessels and improve cardiovascular health, citing a meta-analysis that found magnesium supplementation at an average dose of 368 mg per day notably lowers both systolic and diastolic blood pressure.
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 19 Mar 2015 · Vitamin B6 · recommends · YouTube ↗
      Dr. Patrick states that people with a specific gene polymorphism in the NPF3 gene, which affects vitamin B6 levels, may need to increase their dietary intake of B6 and/or supplement with vitamin B6.
    • 22 Jun 2014 · Vitamin B6 · recommends · YouTube ↗
      Vitamin B6 can suppress the production of Advanced Glycation End products.
    • Date not recorded · Vitamin B6 · neutral · Website ↗
      Dr. Rhonda Patrick explores high-dose vitamin B6.
    • Date not recorded · Vitamin B6 · neutral · Website ↗
      Notes that very high doses of vitamin B6 can overcome a specific mutation in the ornithine aminotransferase enzyme, preventing progressive blindness.
  • Dr. Eric Berg · Magnesium · recommends
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends Magnesium glycinate, noting its high absorption rate compared to magnesium oxide, and its support for energy, sleep, muscle relaxation, and vitamin D function.
    • 7 Nov 2026 · neutral · Instagram ↗
      Dr. Berg states that when nutrients like magnesium are too low, fatigue and weakness can follow.
    • 6 Nov 2026 · recommends · Podcast ↗
      Recommends focusing on magnesium to support stronger bones if a neck hump is associated with osteoporosis.
    • 6 Nov 2026 · neutral · Instagram ↗
      Explains that leg and calf cramps are most often caused by low magnesium, with leafy greens being a top source.
    • 6 Nov 2026 · recommends · YouTube ↗
      States that magnesium is a cofactor that allows B1 to work more efficiently.
    • 4 Nov 2026 · recommends · YouTube ↗
      States that magnesium is the most important mineral for energy production, as one cannot make energy without it.
    • 1 Nov 2026 · neutral · YouTube ↗
      Magnesium is involved in 300 to 600 enzyme reactions, acts as a biological brake pedal, is the master controller over calcium, and is involved in making ATP, the energy currency of the body. It takes energy to go to sleep, and magnesium is required for relaxation and good sleep. Magnesium also helps balance cortisol levels and calm you.
    • 1 Nov 2026 · Vitamin B6 · neutral · YouTube ↗
      States that vitamin B6 is needed to absorb magnesium.
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 10 Oct 2026 · Vitamin B6 · warns · Podcast ↗
      Dr. Berg lists pyridoxine hydrochloride as a synthetic vitamin to avoid.
    • 4 Oct 2026 · Vitamin B6 · recommends · Facebook ↗
      Recommends taking the active form of vitamin B6, pyridoxal-5-phosphate (P5P), for its benefits to the nervous system, including building the myelin sheath and protecting sensory nerve integrity.
    • 4 Oct 2026 · Vitamin B6 · neutral · X ↗
      Notes that Vitamin B6 is intimately involved in the nervous system and may be behind sciatica and carpal tunnel syndrome.
  • Thomas DeLauer · Magnesium · recommends
    • 5 Nov 2026 · recommends · YouTube ↗
      Recommends taking magnesium glycinate and threonate at night to act as a brake on the nervous system, block excitatory signaling, help wind down, and support serotonin and melatonin production for better sleep.
    • 4 Nov 2026 · neutral · YouTube ↗
      Mentions that magnesium glycinate also helps a lot with sleep.
    • 2 Nov 2026 · neutral · YouTube ↗
      Mentions that restless leg syndrome is often treated with magnesium, but states that the sensation is actually coming from three other issues.
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 25 Sep 2026 · neutral · Facebook ↗
      Mentions that magnesium in pumpkin seeds relaxes bronchial smooth muscle.
    • 20 May 2026 · Vitamin B6 · recommends · YouTube ↗
      Recommends ensuring adequate vitamin B6 intake, as it is a required cofactor for cells to use absorbed magnesium and improves central nervous system relaxation when combined with magnesium.
    • 7 May 2026 · Vitamin B6 · recommends · YouTube ↗
      Recommends vitamin B6 to support GABA production and find balance for mental clarity.
    • 27 Feb 2026 · Manganese · neutral · YouTube ↗
      States that a small serving of maple syrup contains 125% of the daily value of manganese.
    • 25 Feb 2026 · Vitamin B6 · neutral · YouTube ↗
      Mentions B12 as a critical B vitamin for reducing homocysteine.
  • Andrew Huberman · Magnesium · recommends
    • 4 Nov 2026 · recommends · Instagram ↗
      Notes that Les Spellman's team includes 'Magnesium timed right' as part of their game plan to optimize recovery in unfavorable conditions.
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 13 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 6 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 22 Jun 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 29 Jul 2024 · Vitamin B6 · warns · YouTube ↗
      Does not supplement B6 due to evidence that overs-supplementing vitamin B, especially B6, is problematic because of peripheral nerve damage.
    • 12 Jun 2023 · Vitamin B6 · neutral · YouTube ↗
      Notes that some people are exploring the use of P5P, a metabolite of vitamin B6 known to suppress prolactin, as a way to buffer the post-MDMA crash, though there are no human data yet.
    • 11 Apr 2022 · Vitamin B6 · recommends · YouTube ↗
      Recommends P5P, which is vitamin B6, as a dopamine agonist to help with low drive and motivation.
    • 12 Apr 2021 · Vitamin B6 · neutral · YouTube ↗
      Described how some people take vitamin B6 to reduce prolactin levels and thereby reduce the duration of the refractory period, but he is not suggesting anyone do this.
  • Dr. Mark Hyman · Magnesium · recommends
    • 4 Nov 2026 · recommends · YouTube ↗
      Recommends magnesium breakthrough advanced ten from Biooptimizers, which is their most complete magnesium formula with 10 bioavailable forms and 550 milligrams of elemental magnesium, designed to support restful restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that a lack of magnesium can cause muscles and nerves to malfunction, resulting in muscle weakness, twitching, and cramps.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 16 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
    • 31 Aug 2026 · Vitamin B6 · uses · YouTube ↗
      Optimized a child's nutrient status with vitamin B6, as the child had low B6 levels.
    • 29 Jun 2026 · Vitamin B6 · recommends · Facebook ↗
      Recommends vitamin B6 with folate and B12 as supplements with strong evidence for PMS.
    • 3 Jun 2026 · Vitamin B6 · neutral · YouTube ↗
      Believes that if functional testing is done to replete deficiencies like vitamin D and B12 before someone stops their medication, withdrawal symptoms can be completely eliminated.
    • 15 Nov 2024 · Vitamin B6 · recommends · YouTube ↗
      States that Vitamin B6, at 50 to 100, is important for estrogen metabolism.
  • Dave Asprey · Magnesium · uses
    • 3 Nov 2026 · uses · Instagram ↗
      Looks at magnesium alongside protein to keep muscle for the long run.
    • 6 Nov 2026 · Manganese · neutral · X ↗
      Mentions that algae provides manganese.
    • 3 Nov 2026 · recommends · YouTube ↗
      Suggests adding magnesium to help keep potassium in the system longer, as they work hand in hand.
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 3 Sep 2026 · Manganese · recommends · YouTube ↗
      Emphasizes the importance of having enough manganese before trying advanced longevity strategies like peptides.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
    • 1 Jan 2026 · Vitamin B6 · neutral · YouTube ↗
      Mentions Vitamin B6 as playing a role in methylation pathways.
    • 25 Sep 2025 · Manganese · recommends · YouTube ↗
      Explains that manganese is crucial for the proper function of SOD in the mitochondria, and without it, SOD will grab iron and become pro-inflammatory. Algae has the highest concentration of manganese.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 15 Aug 2026 · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 13 Jun 2026 · neutral · X ↗
      Notes a new study indicating that magnesium is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
    • 19 Jul 2025 · Vitamin B6 · recommends · YouTube ↗
      Recommends Vitamin B6 for the conversion of tryptophan to serotonin and then melatonin in the pineal gland.
    • 26 Dec 2024 · Manganese · neutral · TikTok ↗
      Discusses new research on how the body can absorb manganese straight from the air through the lungs.
    • 26 Dec 2024 · Manganese · warns · YouTube ↗
      He mentions that manganese is an essential nutrient, but too much of it can harm the brain, citing welders who get harmful levels of manganese buildup from breathing it in.
    • 24 Aug 2023 · Vitamin B6 · neutral · YouTube ↗
      Lists vitamin B6 as a vitamin that, when combined with others, has a neuroprotective effect on the brain.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 17 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 10 Aug 2026 · recommends · YouTube ↗
      Notes that magnesium is important for activating thiamine into its more biologically active form, and a magnesium deficiency can impair blood sugar regulation even with adequate thiamine intake.
    • 28 Mar 2025 · Manganese · uses · YouTube ↗
      Travels with Upgraded Formulas' potassium, manganese, boron, and zinc, considering them fundamental minerals he is usually deficient in.
    • 29 Nov 2024 · Vitamin B6 · neutral · YouTube ↗
      Mentions that insufficient vitamin B6 can raise prolactin levels.
    • 28 Sep 2024 · Vitamin B6 · recommends · YouTube ↗
      Recommends B12 for vegans, noting it is a standard vitamin found in animal products.
    • 13 Aug 2023 · Vitamin B6 · uses · YouTube ↗
      Is experimenting with serine plus vitamin B6 to impact homocysteine levels, a mechanistic hypothesis he is testing.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
    • 20 May 2024 · uses · YouTube ↗
      Takes magnesium as a straightforward supplement.
    • 28 Feb 2024 · neutral · YouTube ↗
      Mentions that magnesium intake is often super low and impactful on testosterone levels.
    • 11 Dec 2023 · uses · Facebook ↗
      Discusses the important roles of magnesium in the body, how to determine if one might be deficient, the prevalence of magnesium deficiency, and its potential cognitive benefits.

RAL Summary

Members OnlyTier 3 for Stress and Calm

Tier 3 because over 10,000 reviews are 91 percent positive, while study support for magnesium easing stress is only modest, with some trials lacking a placebo and others finding no effect [1][3][5].

  • Vitamin B6: trace amount

Where the evidence disagrees: 16 of the 53 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system, Endocrine system, Digestive system, Muscular system

Combine with: For its intended purpose of relaxation, stress and sleep support, magnesium pairs well with L-theanine, ashwagandha, glycine, vitamin B6 (P5P) and vitamin D3/K2, which aid magnesium utilization and calm the nervous system. For fast heartburn relief, look instead to a true antacid such as calcium carbonate or magnesium hydroxide, or to alginate-based products (sodium alginate), which form a protective raft over stomach contents. For longer-term support, consider DGL licorice, zinc-carnosine, aloe vera juice or slippery elm. Check with a healthcare provider if heartburn is frequent or persistent, since magnesium can interact with some medications and acid reducers.

Possible side effects: Some buyers report diarrhea or stomach upset, sometimes eased by splitting the dose. Studies reported no major side effects.

Supplement Facts

Vitamin B6 2 mg · Elemental Magnesium 500 mg · Manganese 1 mg
Supplement Facts
Serving Size 2 Capsule(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Vitamin B62 mg
Elemental Magnesium500 mg†
Manganese1 mg
† Daily Value not established.

Other ingredients: Cellulose, Plant, Nu-Mag.

Directions: Suggest use: Take 2 capsules with your evening meal.

Barcode (UPC) 851335007871 · Label source: NIH label database · Report a label change

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Graded November 11, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.