The Vitamin Shoppe Calcium 1000 1000 mg Review
Get 100% of your daily calcium and vitamin D in an easy to swallow soft gel form, described as a pleasant alternative to mega-sized, hard-to-swallow calcium tablets. The product is sold by The Vitamin Shoppe as a calcium supplement that supports healthy bones and teeth, with 1,000 mg of calcium and 400 IU of vitamin D. Directions state that, as a dietary supplement, adults should take two softgels daily, preferably with meals. The page lists 50 servings, an item form of softgel, a citrus flavor, and a unit count of one. Calcium is described as the most abundant mineral in the human body, helping with dozens of metabolic processes including blood clotting, muscle contraction, nerve transmission, and maintenance of normal blood pressure. The page says most people do not consume enough calcium in their daily diet, so supplementation is highly recommended. Calcium intake can come from dietary sources including dairy and non-dairy products, and calcium supplements such as calcium carbonate and calcium citrate are available as pills, chewable tablets, and liquids. The page states the product does not contain artificial colors or flavors, citrus, corn, dairy, fish, gluten, nut, preservatives, salt, starch, sugar, wheat, or yeast. Warnings advise consulting a healthcare provider before use if pregnant, nursing, taking any medication, or having a medical condition, and to keep the product out of reach. A California Proposition 65 warning notes that consuming the product can expose you to chemicals including lead. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. The item is sold by The Vitamin Shoppe and is non-returnable due to food safety reasons, though damaged or defective items may be refunded or replaced.
We don’t sell supplements. We help you make decisions and get the best price.
Lowest prices
Finding the lowest prices at the stores now. This takes a few seconds.
Products with nearly the same formula (Matched on the main ingredients)
Study, Trial or Testing Result Summary
Members Only25 human studies · 7 improved
Studies of calcium for bone health are mixed. A 2025 review of eleven trials in 43,869 women with thinning bones after menopause found that calcium plus vitamin D modestly improved pelvic bone density. It did not improve spine or hip density and did not reduce fractures [1]. In 40 women after a wrist fracture, 1 gram of calcium a day for a year did no better than placebo for thigh bone mineral [2]. In 39 older women with severe bone thinning, 1200 milligrams a day kept bone mineral stable for two years [3]. A six-year study of 698 older women found dietary calcium unrelated to bone loss [4]. Some surveys linked higher dietary calcium with denser bones, in one case only in women [5][6]. Each serving has 400 international units of vitamin D. A review of older adults found that 700 to 800 units a day cut hip fractures by 26%, while 400 units a day did not help [7]. Two servings reach 800 units. Another review of nine studies found no clear drop in fractures from vitamin D [8]. Animal and cell studies are never counted.
See all 25 studies →Hide the studies
- Across eleven trials with 43,869 postmenopausal women with osteoporosis, calcium plus vitamin D modestly improved pelvic bone density but not spine, femoral neck or total hip density, and did not reduce fractures.The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausa…
- This review of smartphone apps for osteoporosis self-management did not test vitamin D supplements and found no significant effect on vitamin D intake.Digital Health Technologies for Long-term Self-management of Osteoporosis: Systematic Review and Meta-analysis.
- In trials of older adults, 700 to 800 IU a day of vitamin D cut hip fracture risk by 26% and other nonvertebral fractures by 23%, while 400 IU a day gave no significant benefit.Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
- Across nine studies, vitamin D3 did not significantly reduce nonvertebral or vertebral fractures versus placebo or calcium alone, with only a borderline trend toward fewer falls.The effect of cholecalciferol (vitamin D3) on the risk of fall and fracture: a meta-analysis.
- In 23 trials of 1,209 kidney transplant recipients, vitamin D analogues (2 trials, 51 patients) improved lumbar spine and femoral neck bone density versus no treatment, but no trial showed fewer fractures.Interventions for preventing bone disease in kidney transplant recipients: a systematic review of randomized controlled …
- In 18 small trials of 576 children with chronic kidney disease, vitamin D preparations lowered parathyroid hormone levels, but there were few data on growth or bone deformities and no clear differences between preparations.Interventions for metabolic bone disease in children with chronic kidney disease.
- One small trial of 39 people with sickle cell disease found vitamin D3 for six weeks raised blood vitamin D and reduced pain days versus placebo, but no bone outcomes were reported and the evidence was low quality.Vitamin D supplementation for sickle cell disease.
- In a review of 25 observational studies of healthy men aged 50 or older, evidence linking calcium intake to bone density or bone loss was inconsistent or weak.Risk factors for low BMD in healthy men age 50 years or older: a systematic review.
- In nine trials of postmenopausal women without osteoporosis, vitamin D with or without calcium improved vitamin D status and some bone turnover measures, but only one study showed fewer fractures, so a fracture benefit could not be confirmed.Supplementation of vitamin D isolated or calcium-associated with bone remodeling and fracture risk in postmenopausal wom…
- In 500 elderly women with Alzheimer disease who all took 1000 IU of vitamin D2 plus calcium, adding risedronate for 18 months raised bone density 4.1% and cut hip fracture risk compared with placebo, but vitamin D itself was not tested alone and the paper was retracted.The prevention of hip fracture with risedronate and ergocalciferol plus calcium supplementation in elderly women with Al…
- Children whose mothers took 1000 IU of vitamin D3 daily during pregnancy had higher whole-body bone mineral content and density at ages 6-7 than children whose mothers took placebo.Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled…
- In 242 elderly men with Parkinson disease who all took 1000 IU of vitamin D2, adding risedronate for 2 years raised bone density, but vitamin D was not compared against placebo and the paper was retracted.Risedronate and ergocalciferol prevent hip fracture in elderly men with Parkinson disease.
- In 39 older women with severe osteoporosis, 1200 mg of calcium daily with or without 25-hydroxyvitamin D for two years kept bone mineral content stable in both groups, with improved bone mineralization rate in both groups.Histomorphometric effects of calcium or calcium plus 25-hydroxyvitamin D3 therapy in senile osteoporosis.
- In 40 postmenopausal women with wrist fracture, 1 g of calcium daily for one year had no significant effect on femur bone mineral content compared with placebo.Bone mineral content in women with Colles' fracture: effect of calcium supplementation.
- In 2904 US adults aged 60 and over, higher dietary calcium was linked with higher lumbar bone density, but this link held in women and not in men.Association between Dietary Calcium Intake and Bone Mineral Density in Older Adults.
- In 1479 elderly Japanese men, greater milk intake was linked with higher hip and femoral neck bone density and lower bone turnover, though this link weakened after accounting for calcium intake.Greater milk intake is associated with lower bone turnover, higher bone density, and higher bone microarchitecture index…
- In 1098 adults aged 65 and over, higher dietary calcium intake was linked with higher bone density at the hip and spine, while higher urinary sodium was linked with lower bone density.Dietary intake, blood pressure and osteoporosis.
- In 698 placebo-group women over 65 with osteopenia, averaging 886 mg of dietary calcium a day over 6 years, calcium intake was unrelated to bone loss at any site.Dietary Calcium Intake and Bone Loss Over 6 Years in Osteopenic Postmenopausal Women.
- In a survey of 452 women in Alaska, dietary calcium intake was low (about 306 mg a day on average), but the survey did not test calcium supplements, so it shows no effect of calcium on bone.Risk factors for osteoporosis in Alaska Native women: a cross-sectional survey.
- In Tuscany, Italy, most people who broke a hip from 2011 to 2015 were not taking vitamin D supplements, and only 30-35% were on cholecalciferol one year after the fracture; no bone outcome was measured against a comparison group.The use of cholecalciferol in patients with hip fracture.
- Among 173 adults aged 35 to 50, about a quarter had osteopenia; bone density correlated with exercise in women and in the opposite direction in men, and no calcium-specific result was reported.Bone Mineral Density Among Men and Women Aged 35 to 50 Years.
- In 116 obese pre- and post-menopausal women, daily calcium and vitamin D intake was low, especially among premenopausal women with osteoporosis, but the study did not test whether calcium improved bone.Dietary Pattern and Bone Health in Pre and Post-menopausal Obese Women.
- In 52 Parkinson's patients compared with 52 matched controls, lower bone density was seen, and insufficient calcium intake was among the factors related to low bone density.Prevalence and risk factors of osteoporosis in patients with Parkinson's disease.
- In 70 people taking meds, a dedicated bone clinic found many with bone loss; early results showed bone density rose 3 to 5 percent with drug and lifestyle measures, including calcium and/or vitamin D in 44 people.Read the study on PubMed (10678299) →
- In 42 Iranian adults with hemophilia, low bone density was very common, and only cigarette smoking was significantly linked to it, not calcium intake.Bone mineral density in hemophilia patients.
Review Totals and Summary
Members Only51 reviews · 62% positive
Customers on the iHerb listing, which includes reviewers from several countries, mostly praise how easy the softgels are to swallow. A US reviewer said they usually hate calcium tablets because the flat edges make them hard to swallow, and found these a great alternative. Another reviewer called them an excellent substitute for hard calcium tablets. A third said the softgels are easier to take than solid calcium. People with swallowing difficulty or pill fatigue seem to value this most. Reviewers also like the strength and convenience of the product. They liked getting 1,000 mg of calcium in a simple daily routine. Several described the quality and ingredients as consistently good. One reviewer in Korea who takes it during pregnancy and at age 40 for bone health said they are happy with the quality and that it leaves no unpleasant taste. Another reviewer said the size is just right for regular use and for travel, and called the packaging convenient and easy to store. Some reviewers took it for specific health needs, for example a patient with a thyroid condition who said it makes up for a calcium deficiency. Overall, people trust it as a dependable bone-health basic. I found few complaints in the reviews I read. The sample was small, with only a few dozen ratings, and many reviews were marked as rewarded or incentivized. That can skew sentiment positive, so the lack of criticism should be treated with caution. The one practical point that comes from the product itself, not from reviewers, is that a full dose is two softgels, so some users may need to take more than one pill a day. Calcium supplements can also cause constipation or bloating in some people, but I did not see reviewers raise this. In short, customers like the smooth, easy-to-swallow format, the dose, the quality and the convenience. There is little criticism, but the evidence is limited and may be biased.
Biohacker Summary
Members Only8 of 10 recommend it
Vitamin D is listed as the main ingredient here, and nearly the whole panel spoke about it, with most recommending it or taking it themselves. They take it for immune health, brain and mood, bone strength, muscle, and general health or longevity, and several say most people are deficient and should have their blood levels checked. Doses vary: three panelists take 5000 IU of D3 in the morning, one suggests at least 10,000 IU daily in winter, and another points to about 8,895 IU as the real need. Preferred forms are D3, sometimes with K2, and they pair it with magnesium and K2 or with dietary fat for better absorption, while one panelist says it adds little unless you are deficient. Calcium, a smaller ingredient in this product, got only one passing mention, listing dairy and sardines as food sources.
See all 10 biohackers →Hide the biohackers
Dr. Eric Berg · Vitamin D · warns
- Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
- Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
- Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
- Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
- Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
- Recommends increasing vitamin D to restore balance and support healthy blood pressure.
- Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
- States that a lack of vitamin D can potentially cause achy bones or crashing mood.
- States that vitamin D is intimately involved in the immune system and recommends taking at least 10,000 IUs each day.
- States that taking high doses of vitamin D3 for 14 days can improve mood, sleep, low back pain, skin issues, and blood pressure, as well as act as a natural anti-inflammatory and reduce susceptibility to sickness.
- Mentions that grass-fed liver has vitamin D.
- Dr. Berg includes calcium carbonate among the synthetic supplements to avoid.
- Warns against calcium carbonate, also known as limestone, stating that while it lowered hip fractures in a study, it also increased kidney stones and is not good for arteries, requiring the body to work hard to use it.
- Notes that tannins in tea bind calcium, blocking its absorption.
Dave Asprey · Vitamin D · uses
- Takes Vitamin DAKE from Suppgrade Labs.
- Suggests that vitamin D supports brain health, muscle function, and focus.
- Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
- States that currently, he is only taking vitamin C and vitamin D.
- Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
- States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
- Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
- Recommends Vitamin D as one of the most important supplements for overall health.
- Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
- Mentions taking vitamin D in the morning, comparing it to the daily dosing of testosterone.
- Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
- Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
- Notes that people take calcium for their bones.
- Warns that taking calcium without vitamin D, A, and K2 can lead to calcium going into tissues, causing bone spurs and other issues, and recommends a two-to-one ratio of calcium to magnesium.
Siim Land · Vitamin D · recommends
- Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
- Recommends taking Vitamin D with fat for better absorption.
- States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
- Lists dairy and sardines as sources of Calcium.
- Thinks vitamin D has some of the strongest evidence and is worth considering.
- Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
- Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
- Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
- Recommends taking Vitamin D in the morning or at lunch with fat.
- Notes that Boron improves vitamin D.
- Notes that Boron reduces calcium/magnesium loss.
- Recommends Vitamin D because microglia contain Vitamin D receptors, and Vitamin D helps keep the immune system properly regulated, with low levels associated with greater neuroinflammation and a higher risk of autoimmune conditions.
- Recommends a high calcium intake for bone health.
- Places calcium supplementation in the 'bad tier' due to its association with increased cardiovascular events, recommending dairy or bones as easier ways to get calcium, though it can be useful for postmenopausal women with low bone density.
Ben Greenfield · Vitamin D · recommends
- Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
- Mentions vitamin D as part of a bare-minimum protocol.
- Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
- Has been taking Vitamin D3 K2 for over a decade.
- Notes that sunlight influences more than just vitamin D production.
- Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
- Recommends getting enough vitamin D for blood pressure management.
- Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
- Recommends using hormone building blocks like vitamin D for hormone optimization.
- Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
- Notes that vitamin D deficiency is the most common deficiency.
- Mentions calcium as a common deficiency.
- Recommends adequate intake of calcium for bone strength.
- Is using calcium chloride mixed with PRP before injecting for the P-shot.
Dr. Mark Hyman · Vitamin D · recommends
- Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
- Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
- Notes that vitamin D plays a role in immune function.
- Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
- Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
- States that vitamin D supplementation can help with oxidative stress.
- Mentions vitamin D as a key nutrient for supporting immune function.
- States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
- Notes that rickets, which causes terrible bone deformities, is caused by vitamin D deficiency.
- Notes that vitamin D is an important nutrient for brain performance and aging, and that many people have gaps in these nutrients.
- Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
- States that green leafy vegetables are great sources of calcium.
- Notes that calcium needs are lower than advertised and that stress, soda, and excess sugar can drive calcium loss.
- Does not prescribe calcium supplements at all, teaching people to get it from whole foods instead, because calcium supplements don't work for building bones or preventing fractures, and it's bone quality, not density, that matters.
Thomas DeLauer · Vitamin D · uses
- Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
- Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
- Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
- Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
- Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
- Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
- Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
- Recommends getting vitamin D, suggesting it can be obtained while walking.
- States that vitamin D is best obtained from the sun, but getting it from food definitely helps, and notes its role as a hormone influencing many cells.
- Recommends D3, suggesting a dose of 2000-4000 IU, and notes that MK-7 slowed bone loss over three years.
- Recommends vitamin D, especially for Hashimoto's, explaining that it drives T reg expansion to suppress autoimmune responses that attack the thyroid, and notes that vitamin D and selenium deficiencies often co-occur.
- Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
- Explains that eating sardines with their soft bones provides a serious hit of calcium, which is a perfect combination for bones and may contribute to satiety.
- Mentions that magnesium and calcium should not be taken together as they cancel each other out.
Bryan Johnson · Vitamin D · uses
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
- Takes 5000 IU of Vitamin D3 in the morning for longevity.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning.
- He takes 5000 IU of Vitamin D3 in the morning for general health.
- Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
- Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
- Recommends prioritizing calcium intake for postmenopausal women to help maintain bone density and reduce the risk of osteoporosis.
- Bryan Johnson takes Calcium daily as part of his Longevity Mix, which supports healthy bones and teeth.
Dr. Rhonda Patrick · Vitamin D · neutral
- Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
- Mentions that vitamin D also plays a role in maintaining muscle mass.
- Recommends ensuring adequate vitamin D intake for men's sperm health.
- Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
- Lutein and zeaxanthin can also be obtained from certain multivitamins.
- Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
- Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
- Mentions that kale delivers calcium, a micronutrient many diets fall short on.
- Recommends Vitamin D, explaining that it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity.
- Combining omega-3s with vitamin D and exercise has an additive effect, translating to ~3 months of slowed biological aging.
- The effect got stronger when omega-3 was combined with vitamin D and resistance training, with the full stack delaying phenotypic aging by about 3.8 months.
- Notes additional gaps in calcium.
- Reports that alcohol use disorder is associated with a 20-50% greater prevalence of Calcium deficiency.
- Around 38% doesn't meet the requirement for calcium.
Andrew Huberman · Vitamin D · neutral
- Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
- Takes 5,000 IU of Vitamin D3 in the morning for longevity.
- Takes 5000 IU of Vitamin D3 in the morning for general health.
- States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
- Takes 5000 IU of Vitamin D3 in the morning.
- He takes 5,000 IU of Vitamin D3 in the morning for overall health.
- Takes 5000 IU of Vitamin D3 in the morning.
- Takes 5,000 IU of Vitamin D3 in the morning for general health.
- Takes 5000 IU of Vitamin D3 every day for longevity.
- Takes 5,000 IU of Vitamin D3 in the morning.
- Discusses "hard water" and the role of magnesium and calcium in cardiovascular health.
- Adequate intake of calcium is vital for bone health.
Peter Attia · Vitamin D · uses
- Lists vitamin D as one of her staple supplements.
- Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
- States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
- Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
- In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
- Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
- Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
- Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
- Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
- Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
- Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
- Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
- Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
- Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
RAL Summary
Members OnlyTier 4 for Bone Health
Tier 4 because the calcium and vitamin D studies are mixed, with modest gains in pelvic density but no fracture benefit [1]. Also, only 63% of 51 reviews are positive, below the two thirds needed for a higher tier.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 10 of the 25 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Skeletal system
Combine with: For bone health, pair calcium with vitamin D3 to improve absorption, vitamin K2 (MK-7) to help direct calcium into bone rather than soft tissue, and magnesium to support bone mineralization and muscle function. Take calcium in divided doses of 500 mg or less for best absorption, and with food if using calcium carbonate. If blood pressure support is the real goal, consider magnesium, potassium from food, CoQ10, omega-3 fish oil, or beetroot nitrate, and consult a healthcare provider, especially if you take meds.
Possible side effects: No major side effects reported.
Supplement Facts
Calcium 1000 mg · Vitamin D 400 IU
| Calcium | 1,000 mg | |
| Vitamin D | 400 IU |
Other ingredients: Gelatin, Soybean Oil, Water, Glycerin, Titanium Dioxide, Soy Lecithin, Beeswax.
Directions: DIRECTIONS: As a dietary supplement, take two (2) softgels daily, preferably with meals.
Barcode (UPC) 766536014163 · Label source: NIH label database · Report a label change
Show entire label
More bone health products
Members OnlyThe highest ranked for the same goal
Read more
Our articles on this subject
- What Supplements and Vitamins Should Not Be Taken TogetherArticle · Sep 7, 2026
- When Is the Best Time to Take Vitamins and Supplements?Article · Jun 15, 2026
Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
Privacy policyConsumer health dataTermsDo Not Sell or Share My Personal InformationCookie settings