Vitamin World Zygest Multi-Enzyme Review
Tier ⓘ
Tier 3 · Rank 6
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 6 within Tier 3 for Blood Pressure; 19 of 60 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
56 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
95% of 4,200
Biohacker Mentions
0 of 10
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Study, Trial or Testing Result Summary
Members Only42 human studies · 14 improved
42 human studies14 improved21 no effect213,572 people studied
This is a digestive enzyme product. Its main ingredient, the Zygest enzyme blend, has no human studies on blood pressure, and the label does not list the blend's contents or amounts. The calcium here is far below the dose that helped in studies, about 141 milligrams a day versus around 1 gram. In pregnant women, calcium lowered the risk of high blood pressure in pregnancy and of preeclampsia in large reviews [1][2], though a large trial using 2 grams daily found no benefit [3]. In people with normal blood pressure, calcium lowered blood pressure by only about 1 to 1.5 points [4][5]. In adults with high blood pressure, the top number fell by about 2.5 points, but the evidence was judged weak [6]. Phosphorus does not appear to help. A review found no consistent link between phosphorus and blood pressure [7], and a high dairy diet rich in phosphorus did not change blood pressure [8]. In one small trial, extra phosphate raised blood pressure and pulse in healthy young adults [9]. Animal and cell studies are never counted.
See all 42 studies →Hide the studies
- Across 130 trials with about 112,900 pregnant women, calcium supplements lowered the risk of preeclampsia or pregnancy-related high blood pressure (odds ratio 0.71) compared with controls.Comparative effectiveness of prophylactic strategies for preeclampsia: a network meta-analysis of randomized controlled …
- In 50 trials with about 57,800 pregnant women, calcium cut the risk of gestational high blood pressure versus placebo (odds ratio 0.55), and calcium plus a med cut it further (odds ratio 0.12).The preventive effects of different interventions on gestational hypertension: incidence and network meta-analysis.
- In 18 trials with 3,140 people with normal blood pressure, calcium supplements lowered systolic blood pressure by about 1.4 mmHg and diastolic by about 1.5 mmHg versus placebo or control, with larger effects in people under 35.Calcium supplementation for prevention of primary hypertension.
- In 18 trials with 3,140 people with normal blood pressure, calcium supplements lowered systolic blood pressure by about 1.4 mmHg and diastolic by about 1.5 mmHg versus placebo or control, with larger effects in people under 35.Calcium supplementation for prevention of primary hypertension.
- In 16 trials with 3,048 people with normal blood pressure, calcium supplements lowered systolic blood pressure by about 1.4 mmHg and diastolic by about 1 mmHg, with the largest effect at more than 1,500 mg a day.Calcium supplementation for prevention of primary hypertension.
- In 13 trials with 485 adults with high blood pressure followed 8 to 15 weeks, calcium lowered systolic pressure by 2.5 mmHg but not diastolic pressure, and the authors judged the evidence weak because of poor trial quality.Calcium supplementation for the management of primary hypertension in adults.
- A review of 14 intervention studies and 3 long-term cohort studies (about 20,000 adults) found no consistent link between phosphorus eaten in food and blood pressure, and no trial was designed to test it.Dietary phosphorus intake and blood pressure in adults: a systematic review of randomized trials and prospective observa…
- A review of calcium-rich mineral water noted that some studies showed lower blood pressure, but gave no numbers and said more research is needed.Exploring the Potential Benefits of Natural Calcium-Rich Mineral Waters for Health and Wellness: A Systematic Review.
- A review of 34 studies in pregnant women found calcium supplements were linked to less and milder gestational high blood pressure and preeclampsia, with the strongest benefit at 1.5 to 2 grams a day.Calcium Supplementation in Pregnancy: A Systematic Review of Clinical Studies.
- In 4589 healthy first-time pregnant women, 2 g of calcium daily from mid-pregnancy to delivery did not reduce preeclampsia (6.9% vs 7.3% with placebo) or change average blood pressure.Trial of calcium to prevent preeclampsia.
- In 1194 first-time pregnant women, 2 g of calcium daily from week 20 of pregnancy lowered high blood pressure disorders of pregnancy (9.8% vs 14.8% with placebo).Calcium supplementation to prevent hypertensive disorders of pregnancy.
- In 698 healthy adults with high-normal blood pressure, 1 g of calcium daily for 6 months did not significantly change blood pressure compared with placebo, though white women might have benefited.Lack of blood pressure effect with calcium and magnesium supplementation in adults with high-normal blood pressure. Resu…
- In 524 healthy first-time pregnant women, 2 g of calcium daily lowered preeclampsia (4.0% vs 12.0% with placebo) and blood pressure at the end of the study, though this paper was later retracted.Calcium supplementation for the prevention of pre-eclampsia.
- In 260 pregnant teenagers with low calcium intake, 2000 mg of calcium daily from 20 weeks of pregnancy until delivery cut preeclampsia to 3.2% versus 15.5% on placebo and lowered systolic blood pressure by 9.1 and diastolic by 6.0 mmHg.Calcium supplementation and the risk of preeclampsia in Ecuadorian pregnant teenagers.
- In 201 first-time pregnant women, 2 g of calcium daily from 20 weeks until delivery lowered pregnancy-induced high blood pressure to 8.24% versus 29.03% on placebo.Calcium supplementation and prevention of pregnancy induced hypertension.
- In 125 adults with mild untreated high blood pressure, 6 months of calcium (1000 mg daily), alone or combined with potassium or magnesium, did not lower blood pressure more than placebo.Combinations of potassium, calcium, and magnesium supplements in hypertension.
- In 101 fifth-grade children, 600 mg of calcium daily for 12 weeks lowered systolic blood pressure by 1.8 mm Hg versus placebo, though this was not statistically significant overall; the effect was larger in children with low calcium intake and diastolic pressure barely changed.Effect of calcium supplementation on blood pressure in children.
- In a randomized, placebo-controlled crossover trial of 70 adults (43 with hypertension, 27 without), 1000 mg of elemental calcium daily for 8 weeks did not significantly change blood lipids in the hypertensive group, and the abstract reports no blood pressure result; normotensive adults with mildly high cholesterol had a small drop in total cholesterol.Plasma lipids and hypertension: response to calcium supplementation.
- In 57 young adults, 1 g of calcium daily for 22 weeks lowered diastolic blood pressure by 5.6% in women and 9% in men compared with placebo.Reduction of blood pressure with calcium supplementation in young adults.
- In 51 adults with mild essential hypertension, 1 gram of daily oral calcium for 8 weeks lowered systolic blood pressure by up to 6 mm Hg and diastolic by up to 3 mm Hg compared with placebo.[Effect of an oral calcium supplement in the treatment of slight-to- moderate essential arterial hypertension].
- In 49 women with chronic high blood pressure, taking 2 g of calcium plus low-dose a med from mid-pregnancy until delivery did not significantly reduce preeclampsia compared with placebo.Read the study on PubMed (24728212) →
- In 42 adults with kidney disease, higher daily phosphorus intake from diet was linked with lower arterial stiffness, but this was an observational association in a post-hoc analysis of a trial, not a supplement test.Diet quality, unprocessed plant-based foods, and vascular function in adults with CKD: Secondary analysis of a pilot ran…
- In 40 postmenopausal women, a single 1 g calcium citrate dose made the systolic blood pressure drop after breakfast smaller than placebo, by 6 to 9 points over 4 to 6 hours.Acute effects of calcium supplements on blood pressure: randomised, crossover trial in postmenopausal women.
- In 30 high-risk pregnant women, 2 grams of daily calcium from 28 to 32 weeks of pregnancy reduced pre-eclampsia cases from 7 to 1 compared with placebo, but did not meaningfully change pregnancy-related high blood pressure, which was only delayed by about 3 weeks.Supplementary calcium in prevention of pre-eclampsia.
- In 27 adults with high insulin levels, eating about 5.8 dairy servings daily for 6 weeks, a diet higher in phosphorus, did not change blood pressure or arterial stiffness compared with a standard dairy intake.Lack of change in blood pressure and arterial stiffness after high dairy intake in hyperinsulinemic subjects: a cross-ov…
- Over nine months in 22 people with chronic kidney failure, a very-low-protein diet was no better than a conventional low-protein diet, and changes in blood pressure did not track changes in kidney function.Supplemented low-protein diets--are they superior in chronic renal failure?
- In 20 adults with untreated mild to moderate high blood pressure, 2 grams of daily calcium for 12 weeks did not lower blood pressure compared with placebo.Effect of oral calcium supplementation on blood pressure in patients with previously untreated hypertension: a randomise…
- In 20 healthy young adults with normal kidney function, 11 weeks of extra phosphate raised 24-hour systolic blood pressure by about 4 mm Hg, diastolic by about 3 mm Hg and pulse rate by about 4 beats per minute compared with a low-phosphate group, so blood pressure got worse.A Controlled Increase in Dietary Phosphate Elevates BP in Healthy Human Subjects.
- In an 18-person double-blind crossover trial, 1600 mg of elemental calcium daily for one month did not lower blood pressure in adults with mild to moderate untreated hypertension compared with placebo.Does oral calcium supplementation lower high blood pressure? A double blind study.
- In 8 people with insulin-dependent diabetes and early kidney damage, a three-week low-protein diet supplemented with phosphate lowered urine albumin but did not change arterial blood pressure.Effect of protein restriction in insulin dependent diabetics at risk of nephropathy.
- In a randomized trial of pharmacist involvement in dialysis care, blood phosphorus fell, but blood pressure changes were minimal.Randomized Trial of Pharmacist Integration in Haemodialysis Teams: Effects on Phosphorus Control and Patient Outcomes.
- In 400 pregnant women, 375 mg of calcium plus 1,200 IU of vitamin D daily from 20-24 weeks lowered blood pressure in women without toxaemia, but toxaemia rates (6% versus 9%) did not differ significantly.Effect of calcium and vitamin D supplementation on toxaemia of pregnancy.
- In 50 free-living volunteers, 1,150 mg of daily dietary calcium from dairy for 6 months lowered systolic blood pressure compared with an orange juice control, though the result was not strongly significant and diastolic blood pressure did not change.Dietary calcium. A method of lowering blood pressure.
- In 45 adults aged 50 or older given one sodium phosphate enema, blood pressure and pulse were recorded, but the main finding was transient high blood phosphate, with no blood pressure benefit reported.Serum electrolyte shifts following administration of sodium phosphates enema.
- In 1098 older adults, dietary calcium was linked to better bone density, and this study did not report a calcium link to blood pressure.Dietary intake, blood pressure and osteoporosis.
- In a random sample of 976 people in Cape Peninsula, hypertensive adults had lower calcium intakes than normotensive adults, but this cross-sectional survey did not test calcium supplementation and so cannot show that calcium lowers blood pressure.Hypertension in the coloured population of the Cape Peninsula.
- In 973 African American adults, higher dietary phosphorus was not linked to higher blood pressure or hypertension, though some measures were linked to lower diastolic pressure.Dietary Phosphorus and Ambulatory Blood Pressure in African Americans: The Jackson Heart Study.
- In 662 children with high cholesterol, higher dietary calcium intake was linked to lower blood pressure over 3 years, but this observational study cannot prove cause.Nutrient intake and blood pressure in the Dietary Intervention Study in Children.
- A descriptive survey of 167 free-living elderly Greeks found high blood pressure to be common and calcium intake above half of the US recommended allowance, but it did not test any calcium supplement or report a blood pressure effect of calcium.Nutrition status of the elderly in Anogia, Crete, Greece.
- In a German and Swiss study of 128 children with X-linked hypophosphatemia, blood pressure was higher than in healthy children and tracked with body weight (BMI), with no difference between burosumab and phosphate-supplement treatment.Office Blood Pressure and Obesity in Children with X-Linked Hypophosphatemia.
- In 70 peritoneal dialysis patients followed for at least 3 years, high serum phosphorus and high-sensitivity CRP were independent risk factors for new coronary artery calcification; this study looked at phosphorus levels in the blood, not supplemented phosphorus, and did not measure blood pressure as an outcome.Hyperphosphatemia and hs-CRP Initiate the Coronary Artery Calcification in Peritoneal Dialysis Patients.
- A review of 19 calcium supplement trials found most showed no significant blood pressure effect, and pooled estimates suggested only a small reduction of about 1.8 mmHg in systolic pressure, so the authors called the evidence suggestive but not conclusive.Calcium and blood pressure. An epidemiologic perspective.
Review Totals and Summary
Members Only4,200 reviews · 95% positive
4,200 reviews · Google Shopping 4,200
95% positive0% neutral5% negative
Extensive customer reviews and qualitative feedback are currently being aggregated for this product. Check back soon for a detailed sentiment analysis.
Biohacker Summary
Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it
The main ingredient here is calcium, with phosphorus listed alongside it, and the panel is split on calcium in supplement form. Most of the panel backs getting enough calcium for bone health, with a few giving doses of 1,000 to 1,200 milligrams a day, but four of them warn against supplements and prefer food such as sardines, dairy or leafy greens, citing heart risk or weak results for bones. Those who are open to supplements name calcium citrate or calcium carbonate, though one calls carbonate the worst source, and one takes a calcium and magnesium pill. Others advise pairing calcium with vitamin D, vitamin A and K2, and keeping about two parts calcium to one part magnesium, while one says the two should not be taken together; one person told people to stop calcium supplements. Only two of the ten spoke about phosphorus, and both treated it as a bone-building mineral that works with calcium.
See all 10 biohackers →Hide the biohackers
Dr. Eric Berg · Phosphorus · neutral
- Lists phosphorus as an ingredient found in sardines.
- States that one can of sardines contains 382 mg of calcium.
- Warns against calcium supplements, citing studies that link them to a higher risk of heart attack, especially in postmenopausal women, and suggests getting calcium from dairy instead.
- Recommends focusing on calcium to support stronger bones if a neck hump is associated with osteoporosis.
- Warns against calcium carbonate, calling it limestone and the worst source of calcium, stating it takes 12 steps to be converted in the body and is like eating rocks.
- Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
- Dr. Berg includes calcium carbonate among the synthetic supplements to avoid.
- Warns against calcium carbonate, also known as limestone, stating that while it lowered hip fractures in a study, it also increased kidney stones and is not good for arteries, requiring the body to work hard to use it.
- Notes that tannins in tea bind calcium, blocking its absorption.
- Indicates that horizontal thin white lines near the base of the nails are indicative of low calcium.
- Warns that calcium carbonate can build up in the arteries and kidneys and increase the risk of a heart attack.
- Recommends increasing phosphorus for best kidney health.
- Warns that the damaging phosphorus is found in junk food like Coke, as it is absorbed 100%, unlike phosphorus from other foods.
- Notes that Parmigiano Reggiano contains a high amount of phosphorus for bones.
Siim Land · Calcium · neutral
- Lists dairy and sardines as sources of Calcium.
- Notes that Boron reduces calcium/magnesium loss.
- Recommends a high calcium intake for bone health.
- Places calcium supplementation in the 'bad tier' due to its association with increased cardiovascular events, recommending dairy or bones as easier ways to get calcium, though it can be useful for postmenopausal women with low bone density.
- Mentions that eating enough calcium matters for bone density, but states that it alone won't transform bone density.
- Warns that calcium is linked to a higher risk of heart disease, though people with low calcium status and intake can take it safely.
- Warns that calcium supplements increase the risk of heart disease by raising blood calcium levels too high, leading to hypercalcemia and more calcium being stored in the arteries, and also increase the risk of arrhythmias.
- Warns against calcium supplementation for most people due to its association with increased cardiovascular events, but notes it can be useful for postmenopausal women with low bone density who don't consume dairy.
- Discusses Calcium as a supplement.
- Recommends consuming calcium from dairy, tofu, leafy greens, and bones, as it is a key nutrient required for ATP synthase in mitochondrial energy production.
- Warns that a diet too high in phosphorus, especially in the absence of sufficient magnesium, can damage kidneys and lead to kidney disease.
- Attributes an improvement in his kidney function to a reduction in phosphorus intake, which in excess can negatively affect kidney function.
- Warns that phosphorus in excess is bad.
- Warns that consuming too much phosphorus can accelerate the decline in kidney function, promote vascular calcification, heart disease, and increase the risk of mortality in both healthy and sick people.
Thomas DeLauer · Calcium · neutral
- Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
- Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
- Explains that eating sardines with their soft bones provides a serious hit of calcium, which is a perfect combination for bones and may contribute to satiety.
- Mentions that magnesium and calcium should not be taken together as they cancel each other out.
- Tries to get multivitamins without calcium or with a low amount, as he believes supplemental calcium impacts the absorption of other vitamins and minerals and is not as beneficial as hyped. He cautions against it for most people due to the risk of coronary artery calcification.
- Recommends getting calcium from dairy sources like milk, yogurt, kefir, and cheese in the morning to support neurotransmitter synchronization crucial for deep and REM sleep, noting that low dietary calcium is linked to insomnia.
- Warns that calcium competes with magnesium for the same absorption channels, advising to separate magnesium intake from calcium supplements or dairy by at least an hour or two.
- Recommends providing the body with adequate dietary calcium, not a calcium supplement, to ensure a clean, strong spark for efficient insulin release.
- Warns that calcium and magnesium should not be taken together as they cancel each other out, though some products use delayed absorption to mitigate this.
- Warns that most people consume too much calcium relative to magnesium, which can disrupt the balance needed for proper bodily function, comparing it to an electrical circuit.
- States that phosphorus is extremely rich in turkey and is a critical cofactor for anabolism and protein synthesis, which is imperative at the end of a fast to rebuild or protect muscle tissue.
- Explains that phosphorus is exceptionally high in turkey and is important for proper protein synthesis after a longer fast, as phosphorus levels tend to decline.
- Recommends restoring phosphorus levels after fasting, which can be obtained from pork jerky.
- Suggests adding phosphorus with the break fast meal if one is really trying to keep electrolytes balanced.
Dr. Mark Hyman · Calcium · recommends
- Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
- States that green leafy vegetables are great sources of calcium.
- Notes that calcium needs are lower than advertised and that stress, soda, and excess sugar can drive calcium loss.
- Does not prescribe calcium supplements at all, teaching people to get it from whole foods instead, because calcium supplements don't work for building bones or preventing fractures, and it's bone quality, not density, that matters.
- Warns that acid blockers inhibit calcium absorption.
- Lists calcium as another important nutrient that people can be tested for and measured.
- States that high doses of calcium supplementation in the elderly were not really impacting bone density, as osteopenic patients still became osteoporotic.
- Warns that meds (meds) impair the absorption of calcium, which increases the risk of hip fractures and osteoporosis.
- Recommends calcium citrate, about 600 milligrams a day, for bone health, noting that much can also be obtained from diet through leafy greens, sesame seeds, tahini, and chia seeds.
- Dr. Hyman notes that while calcium deficiency is not common in terms of blood levels, insufficient intake can lead to osteoporosis as the body pulls calcium from bones. He advises caution with calcium supplementation due to potential heart issues.
- States that phosphorus is less of an issue for most people because it's in food.
Dr. Rhonda Patrick · Calcium · neutral
- Mentions that kale delivers calcium, a micronutrient many diets fall short on.
- Notes additional gaps in calcium.
- Reports that alcohol use disorder is associated with a 20-50% greater prevalence of Calcium deficiency.
- Around 38% doesn't meet the requirement for calcium.
- Takes a calcium-magnesium pill because he believes people tend to be short of both and that the body cares about the ratio of these similar molecules.
- States that 1,000 milligrams of calcium per day is the recommended intake for bone density, and supplementation is an option if this requirement is not met.
- Takes a calcium, vitamin K2, and vitamin D combination supplement in the morning, providing about 600 mg of calcium and another 1,000 IUs of vitamin D.
- Dr. Rhonda Patrick discusses calcium needs.
Dave Asprey · Calcium · neutral
- Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
- Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
- Notes that people take calcium for their bones.
- Warns that taking calcium without vitamin D, A, and K2 can lead to calcium going into tissues, causing bone spurs and other issues, and recommends a two-to-one ratio of calcium to magnesium.
- Recommends taking calcium citrate during a high oxalate meal to bind the oxalate in the gut.
- Notes that people often take calcium for bone health.
- Believes calcium supplements are overrated, as most people need more vitamin K2 and vitamin D instead.
- Advises taking iron and calcium separately because they will bind together.
- Takes extra calcium to help deal with the burden when eating chocolate or anything with higher levels of oxalates.
- Discusses calcium citrate as a counter to oxalate crystals, specifically when consumed through dairy, but questions if it's the primary form of calcium in dairy.
Ben Greenfield · Calcium · neutral
- Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
- Mentions calcium as a common deficiency.
- Recommends adequate intake of calcium for bone strength.
- Is using calcium chloride mixed with PRP before injecting for the P-shot.
- Advises people to stop taking calcium supplements as part of the Root Cause Protocol.
- Warns that in high doses, calcium without the right cofactors can raise cardiovascular risk by contributing to arterial calcification instead of bone strength, and may increase the risk of osteoporosis.
- Explains that 10X separates calcium and zinc into different micro beads, releasing them at different rates and locations in the digestive tract to prevent competition and optimize absorption.
- Covers calcium as a key supplement for kids.
- Warns of calcium deficiency on a carnivore diet, as there is not an appreciable amount in meat, and recommends eating fish with bones or taking a calcium supplement or bone mineral matrix.
- Notes that excess calcium intake can contribute to calcium buildup in the arteries.
- Ben recommends taking phosphorus between meals.
Peter Attia · Calcium · recommends
- Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
- Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
- Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
- Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
- Notes that bone is 50 to 70 percent mineral, with calcium being the predominant mineral, and virtually all of the body's calcium is contained within bone.
- Recommends getting about a gram of calcium a day from organic bone meal, which provides calcium hydroxyapatite, the form humans are meant to consume.
- Suggests that calcium is one of the other signals involved in regulating mitochondrial number, beyond AMPK activation.
- States that in postmenopausal women not on estrogen, calcium and vitamin D have no protective effect against hip fracture because the problem is not the shell of the bone, which is fed by calcium and vitamin D, but the internal girder network.
- Notes that compelling evidence links calcium to reduced risk of osteoporosis, which can impact mortality from specific causes.
Bryan Johnson · Phosphorus · recommends
- Recommends phosphorus as a mineral that, along with calcium, magnesium, and boron, is deposited to fortify the bone structure.
- Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
- Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
- Recommends calcium at 1,200 mg daily for women during the follicular phase, depending on dietary intake.
- Recommends prioritizing calcium intake for postmenopausal women to help maintain bone density and reduce the risk of osteoporosis.
- Bryan Johnson takes Calcium daily as part of his Longevity Mix, which supports healthy bones and teeth.
Andrew Huberman · Calcium · neutral
- Discusses "hard water" and the role of magnesium and calcium in cardiovascular health.
- Adequate intake of calcium is vital for bone health.
RAL Summary
Members OnlyTier 3 for Blood Pressure
It sits in tier 3 because of its many reviews, 95 percent of them positive, while study support for blood pressure is thin: calcium is well below the studied dose, phosphorus showed no benefit [7], and the enzyme blend has no human studies.
- Calcium: below the dose that worked in studies
Where the evidence disagrees: 21 of the 42 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system, Cardiovascular system
Combine with: Combine with a healthy diet and lifestyle.
Possible side effects: In one small trial, extra phosphate raised blood pressure and pulse in healthy young adults. No other major side effects were reported.
Supplement Facts
Calcium 141 mg · Phosphorus 109 mg · Zygest Blend 425 mg
Supplement Facts
Serving Size 2 Tablet(s)
Servings Per Container 50
Amount Per Serving% Daily Value
| Calcium | 141 mg | |
| Phosphorus | 109 mg | |
| Zygest Blend | 425 mg | † |
† Daily Value not established.
Other ingredients: Dicalcium Phosphate, Vegetable Cellulose, Stearic Acid, Contains Less Than 2% of.
Directions: DIRECTIONS: For adults, take two (2) tablets before or after meals.
Barcode (UPC) 766443103325 · Label source: NIH label database · Report a label change
Other sizes and barcodes: 200 Easy To Swallow Coated Tablet(s), UPC 7 66443 12554 9 (not checked yet)
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Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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