Celsius Sparkling Cola Review

CELSIUS Sparkling Cola, Sugar Free Energy Drink, 12 Fl Oz (Pack of 12) is listed on this Amazon page as a carbonated energy drink in the cola flavor. The product is sold as a pack of twelve 12 fluid ounce cans, with a unit count of 144 fluid ounces. The page lists the item form as liquid and the package type as can. The listing is sold and shipped by Amazon.com, with the brand listed as CELSIUS and the manufacturer as Celsius, Inc. The page shows a current one-time price of $19.98, or $0.14 per fluid ounce, and a Subscribe and Save option at $18.98, or $16.98 with 15 percent savings, depending on the selected delivery frequency. According to the About this item section, the drink is marketed as functional, essential energy with 200mg of caffeine, intended to help customers live fit. The page states that it is made with premium, proven ingredients and seven essential vitamins. It is labeled as having no sugar, no high fructose corn syrup, no aspartame, and no artificial flavors or colors. The listed diet types are gluten free, kosher, and vegan, and the page also describes the product as non-GMO and certified vegan. The item details list specialty features including low calorie, no artificial colors, no artificial flavors, and sugar free. The recommended uses are pre-workout and general fitness or wellness, and the specific uses listed are workout and energy boost. The product is listed with a flavored drink type of carbonated flavored drink and a liquid contents description of carbonated energy drink. The item details also list the UPC as 889392000566, the global trade identification number as 00889392000566, and the model number as FGSS1207. The best sellers rank shows the product at number one in Grocery and Gourmet Food and number one in Energy Drinks. The ingredients listed include carbonated filtered water, taurine, citric acid, caramel color, guarana seed extract, green tea extract, caffeine, calcium carbonate, phosphoric acid, ascorbic acid, sucralose, glucuronolactone, natural flavor, ginger root extract, calcium pantothenate, niacinamide, pyridoxine hydrochloride, riboflavin, chromium chelate, biotin, and cyanocobalamin. The page also lists the item as non-returnable due to food safety reasons, although damaged or defective items may be refunded or replaced through Your Orders. The product is shown with 4.6 out of 5 stars from 4,592 ratings on the page. Other CELSIUS flavors appear as separate listings on the page, including Cherry Cola, Assorted Flavor Variety, and several Fizz Free options, and the flavor selector shows Cola as the selected option.

Product Focus: EnergyAlso covers:BrainMetabolism
Tier ⓘ
Tier 4
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
62 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
90% of 37,275
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only117 human studies · 44 improved

13 of these 117 human studies gave the ingredient by drip or injection, not by mouth.

117 human studies44 improved58 no effect58,953 people studied

The main energy ingredients are in a 1.81 gram proprietary blend, and no human studies of that blend were provided, so its amounts and effects are unknown. Riboflavin is at a full dose. One trial in construction workers found less fatigue [1], but a larger trial of a nutrient mix with riboflavin found no fatigue benefit [2]. Vitamin C here is below the studied dose. It helped mainly people with low vitamin C [3], while a large trial in people who were not low found no benefit [4]. Vitamin B6 and calcium are at trace amounts compared with the doses studied [5][6]. Niacin and related vitamin B3 forms did not ease tiredness across 27 studies [7]. Vitamin B12 did not boost energy in people who were not deficient [8]. Pantothenic acid did not improve exercise performance [9], and chromium showed no stamina benefit [10]. Biotin's only human support is an uncontrolled study of a mixed product in people with fatigue after a coronavirus infection [11]. Animal and cell studies are never counted.

See all 117 studies →Hide the studies

Review Totals and Summary

Members Only37,275 reviews · 90% positive
37,275 reviews · Walmart 32,500 · Amazon 4,592 · Vitamin Shoppe 183
90% positive1% neutral9% negative

With about 37092 ratings across various stores, Celsius Sparkling Cola generally receives a positive reception, with 80% of reviewed experiences earning 4 or 5 stars. This indicates a strong preference for the product among a large number of consumers. **What it did for them** Many customers report that Celsius Sparkling Cola provides an effective energy boost. They appreciate that this energy is often described as smooth, without the jitters or subsequent crash associated with other energy drinks. Reviewers mention it "gets me going for the afternoon with the energy" and is "Perfect for workouts." Some users also noted benefits related to metabolism and weight management, with comments like "burns fat" and "jump starts your metabolism." The drink is frequently praised as a healthier alternative to traditional sodas and energy drinks, highlighting its "better ingredients," "low calories and no sugar," and "natural energy instead of feeling the jittery energy." **Complaints** While the product itself receives high marks, a recurring theme of dissatisfaction centers on shipping and product quality upon arrival. Customers reported issues such as "arrived with 3 cans empty," "Expired product received," and "Arrived super flat. No carbonation at all." These logistical problems led to frustration and a feeling that the purchase was "Not worth the cost if some cans are empty." The price is also a point of contention for some, who find it "a bit pricey" or "Too expensive." **Taste and Form** The taste of Celsius Sparkling Cola is a major highlight for many, often compared favorably to traditional sodas. Reviewers describe it as having a "Great taste" and an "awesome" cola flavor, with one exclaiming, "taste like I am drinking soda." It's frequently noted for being "similar to original coke but low calorie" and "tastes like cola but not too sweet." However, a few reviews mentioned issues with carbonation, with some cans arriving "super flat" or having "zero carbonation," leading to a taste described by one as "does taste like flat soda." The product is consistently sold as a sparkling liquid in cans. Reviews of other forms, such as gummies or capsules, were not included in this summary. **Value for Money** Opinions on value are mixed. While some customers find the product "a bit pricey" or "Too expensive," others implicitly accept the cost for its benefits, stating they "try to get it as often as I can!" One review even suggested it's "more affordable than most other drinks" when comparing it to other energy drink options. The perceived value often ties into the effectiveness and healthier profile of the drink. **Who it suits and who it did not** Celsius Sparkling Cola appears to be well-suited for individuals seeking a functional beverage that delivers a clean energy boost for daily activities or workouts, without the negative side effects of jitters or crashes. It appeals to those looking for a "healthy cola" alternative with "low calories and no sugar." It also seems to suit people who want a metabolism boost. Conversely, it may not suit those who are highly sensitive to price or who have experienced issues with product delivery and quality, such as flat cans or damaged packaging.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

On biotin, the main ingredient, the panel is split and lukewarm: two of ten recommend it for hair strength and hair follicle growth, four are neutral with only passing mentions, and three warn. One of the warners calls it overhyped and says enough protein is probably more useful for hair, skin and nails, while two others caution that biotin supplements can throw off blood tests for testosterone and estrogen, so they advise avoiding it before such a test. The two who recommend it point to keratin production and name eggs, almonds and salmon as food sources, and nobody gave a dose or a preferred form. Nobody said they take biotin themselves or stopped taking it, and no one paired it with anything. Vitamin C, calcium, vitamin B12 and chromium are smaller ingredients in this product, and the panel talked about them far more than about biotin, mostly praising vitamin C for collagen and immunity.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Biotin · neutral
    • 26 Sep 2026 · neutral · Facebook ↗
      States that thinning hair often indicates low biotin, which is required to produce keratin for hair, skin, and nails.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 25 Oct 2026 · Calcium · warns · YouTube ↗
      Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 19 Oct 2026 · Niacin · recommends · Podcast ↗
      States that expensive NAD+ supplements only turn into $5 niacin in the body and that research has shown niacin can actually raise NAD levels in the blood 5 to 8 times their baseline levels.
    • 17 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Highly recommends taking natural food vitamin C, about 500 mg, at the first sign of a cold.
    • 11 Oct 2026 · Niacin · recommends · YouTube ↗
      Recommends cheap flush niacin, stating that it outperforms expensive NAD supplements and even IV drips in raising NAD levels in the blood.
    • 10 Oct 2026 · Calcium · warns · Podcast ↗
      Dr. Berg includes calcium carbonate among the synthetic supplements to avoid.
    • 10 Oct 2026 · Vitamin B6 · warns · Podcast ↗
      Dr. Berg lists pyridoxine hydrochloride as a synthetic vitamin to avoid.
    • 4 Oct 2026 · Vitamin B6 · recommends · Facebook ↗
      Recommends taking the active form of vitamin B6, pyridoxal-5-phosphate (P5P), for its benefits to the nervous system, including building the myelin sheath and protecting sensory nerve integrity.
    • 4 Oct 2026 · Vitamin B6 · neutral · X ↗
      Notes that Vitamin B6 is intimately involved in the nervous system and may be behind sciatica and carpal tunnel syndrome.
    • 4 Oct 2026 · Vitamin B12 · recommends · Facebook ↗
      Recommends taking the natural form of vitamin B12, methylcobalamin, to support nerve regeneration, myelin production, and nerve growth factors.
  • Thomas DeLauer · Biotin · warns
    • 13 Jun 2026 · warns · YouTube ↗
      Thinks biotin is a little overhyped, suggesting that consuming adequate protein is probably more effective for hair, skin, and nails. He notes that some people might be deficient, especially if consuming a lot of eggs with avidin, but doesn't consider it the 'Mecca of perfect hair'.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 18 Sep 2026 · Vitamin C · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 18 Sep 2026 · Calcium · neutral · Facebook ↗
      Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
    • 5 Sep 2026 · Niacin · uses · YouTube ↗
      Uses niacin as part of their detoxification protocol, taking enough to flush about half an hour before a sauna session.
    • 29 Aug 2026 · Vitamin C · neutral · Instagram ↗
      States that collagen synthesis is vitamin C dependent, in the context of glowing skin.
    • 25 Aug 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for sleep, noting that intake in the range of 125 to 200 mg per day is associated with a lower risk of sleep disorders and sleep apnea, with the benefit plateauing beyond this range.
    • 19 Aug 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming a little bit of vitamin C, such as a couple of berries or kiwi, along with flavanol-rich cocoa to help the delicate flavanols hold up and prevent oxidation in the gut.
    • 12 Aug 2026 · Calcium · recommends · YouTube ↗
      Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
    • 8 Aug 2026 · Vitamin C · neutral · YouTube ↗
      Explains that vitamin C improves the ability of neutrophils to engulf bacterial infections, and that they have a greater ability to engulf larger infections.
  • Dave Asprey · Biotin · neutral
    • 14 Apr 2026 · neutral · TikTok ↗
      States that biotin clears out oxalates.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
    • 25 Jul 2026 · Vitamin C · neutral · Facebook ↗
      Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
    • 25 Jul 2026 · Niacin · recommends · YouTube ↗
      Recommends niacin, a form of vitamin B3, as one of the two most important raw materials for NAD+ production, found in foods like beef liver, chicken, turkey, and fish, or from supplements.
    • 16 Jul 2026 · Vitamin C · warns · YouTube ↗
      Dave Asprey recommends taking maybe a gram of vitamin C a day in divided doses, noting that plasma levels peak around 250 milligrams twice a day.
    • 14 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Qualia Vitamin C Plus, highlighting its combination of seven forms of vitamin C with 250 mg of citrus bioflavonoids, which helps with absorption and use for building collagen and a strong immune system.
    • 9 Jul 2026 · Vitamin C · warns · YouTube ↗
      Warns that taking too much vitamin C can raise oxalate levels, emphasizing that everything has risk and reward.
    • 1 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      States that Vitamin B12 is extremely important for every kind of brain function and recommends ensuring B12 levels are optimal, around 500, not just barely above normal.
    • 16 Jun 2026 · Calcium · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
    • 14 Jun 2026 · Vitamin C · recommends · Podcast ↗
      Recommends Vitamin C as the real biological fix for deep focus issues, explaining how the brain hoards it at levels 100 times higher than blood and how to bypass the blood-brain barrier.
    • 12 Jun 2026 · Calcium · neutral · Instagram ↗
      Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
    • 12 Jun 2026 · Calcium · neutral · X ↗
      Notes that people take calcium for their bones.
  • Andrew Huberman · Biotin · neutral
    • 13 Apr 2026 · neutral · Podcast ↗
      Mentions biotin.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 15 Dec 2025 · Vitamin B12 · neutral · YouTube ↗
      States that a deficiency in vitamin B12 can be terrible and lead to chronic fatigue-like syndromes, as many parts of mitochondria require B vitamins.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
    • 16 Jun 2025 · Vitamin C · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
    • 28 Apr 2025 · Vitamin C · uses · YouTube ↗
      Started taking AG1 in 2012 and still takes it every single day to ensure he meets his quota for daily vitamins and minerals and to support gut health, which is critical for proper brain function, immune system, and neurotransmitter production.
    • 3 Feb 2025 · Vitamin C · uses · YouTube ↗
      Has been taking AG1 daily since 2012 because it is the highest quality and most complete foundational nutritional supplement, ensuring he gets all necessary vitamins, minerals, and micronutrients for daily health.
    • 18 Nov 2024 · Vitamin C · uses · YouTube ↗
      Has been drinking AG1 since 2012, finding it difficult to get enough vitamins, minerals, micronutrients, and adaptogens from diet alone. He finds that taking AG1 daily improves all aspects of his health, including physical and mental health, performance, recovery from exercise, and immune system strength, and also notices more mental clarity and energy.
    • 14 Oct 2024 · Vitamin C · recommends · YouTube ↗
      Recommends AG1 as the highest quality and most complete foundational nutritional supplement, containing vitamins, minerals, probiotics, prebiotics, and adaptogens to cover dietary gaps and support a demanding life.
    • 7 Oct 2024 · Vitamin B12 · recommends · YouTube ↗
      Recommends taking methyl B12 as part of methylated B vitamins to lower homocysteine levels and reduce cardiovascular risk.
    • 7 Oct 2024 · Vitamin B2 · neutral · YouTube ↗
      Mentions that Riboflavin (Vitamin B2) hits cytochrome 2 in the mitochondrial electron transport chain, contributing to energy production.
    • 12 Aug 2024 · Vitamin C · uses · YouTube ↗
      States that AG1 is the highest quality and most complete foundational nutritional supplement available, containing vitamins, minerals, probiotics, prebiotics, and adaptogens, and that he has been taking it daily since 2012, often twice a day, to bolster his energy, immune system, and gut microbiome.
    • 2 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Huberman mentions that vitamin C seems to help with the absorption or utilization of collagen protein.
  • Siim Land · Biotin · neutral
    • 8 Nov 2025 · neutral · YouTube ↗
      Siim Land's company has published papers and filed patents for improvement in mitochondria in the skin using their core mitochondrial approach and other things like biotin.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 30 Sep 2026 · Calcium · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 14 Aug 2026 · Calcium · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
    • 26 Jul 2026 · Chromium · recommends · X ↗
      Recommends chromium as a mineral that can lead to better body composition.
    • 9 Jul 2026 · Vitamin C · neutral · YouTube ↗
      Mentions vitamin C in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
    • 4 Jul 2026 · Vitamin C · uses · YouTube ↗
      Was found to be vitamin C deficient by True Health and Mayo Clinic tests, and now addresses this by eating one extra kiwi fruit daily.
    • 27 Jun 2026 · Chromium · uses · YouTube ↗
      Would take chromium for pre-diabetes.
  • Dr. Rhonda Patrick · Biotin · warns
    • 9 Sep 2025 · warns · YouTube ↗
      Advises avoiding biotin-containing supplements before a testosterone blood test as they can cross-detect with estrogens and confound results.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 29 Jun 2026 · Calcium · neutral · Facebook ↗
      Mentions that kale delivers calcium, a micronutrient many diets fall short on.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 9 Jan 2026 · Vitamin C · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 9 Jan 2026 · Calcium · neutral · Facebook ↗
      Notes additional gaps in calcium.
    • 29 Dec 2025 · Vitamin C · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 8 Oct 2025 · Vitamin B12 · warns · Facebook ↗
      Warns that Vitamin B12 enhances light's melatonin-suppressing effects and should be avoided too close to bedtime.
    • 9 Sep 2025 · Vitamin C · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
    • 4 Sep 2025 · Vitamin C · neutral · Facebook ↗
      Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory.
    • 11 Aug 2025 · Vitamin C · uses · X ↗
      Currently takes the Pure Encapsulations O.N.E Multivitamin.
    • 26 Jun 2025 · Vitamin C · uses · Facebook ↗
      Rhonda's current supplement routine includes Vitamin C.
  • Peter Attia · Biotin · warns
    • 11 May 2025 · warns · YouTube ↗
      Warns that biotin, found in many supplements, can completely obscure findings and render a non-LCMS test for estradiol and testosterone irrelevant due to interference with ELISA-based assays.
    • 9 Jul 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 6 Jul 2025 · Calcium · neutral · YouTube ↗
      Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 29 Jun 2025 · Niacin · uses · YouTube ↗
      Peter Attia's AVIA Skincare vitamin C serum also contains niacinamide, which is useful to apply to the skin right after washing.
    • 22 Oct 2024 · Calcium · recommends · YouTube ↗
      Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
    • 21 Oct 2024 · Calcium · recommends · YouTube ↗
      Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
    • 9 Sep 2024 · Vitamin B12 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as B12, can be a cause of hair loss in women.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
    • 26 Feb 2024 · warns · YouTube ↗
      Advises that if taking a biotin supplement, one should discontinue it for at least a few days, if not a week, before a blood test, as it can dramatically skew thyroid values.
    • 9 Oct 2023 · warns · YouTube ↗
      Warns that certain things, like biotin, should not be taken before a blood test because they can mess up readings.
    • 30 Jan 2023 · Niacin · stopped · YouTube ↗
      Used to prescribe niacin to many patients, primarily to raise HDL, lower APO B, triglycerides, LDL, and LP(a), but stopped after clinical trials showed minimal or disappointing effects on reducing cardiovascular events.
  • Ben Greenfield · Biotin · recommends
    • 22 Feb 2025 · recommends · YouTube ↗
      Recommends biotin (Vitamin B7) for supporting keratin production and strengthening hair, noting it can be found in eggs, almonds, and salmon.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Chromium · neutral · YouTube ↗
      Mentions chromium as a secondary ingredient in blood sugar control products, along with vanadium and bittermelon extract.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 29 Aug 2026 · Niacin · neutral · YouTube ↗
      States that Nrf2 activators, when combined with something like niacin, may have a good effect on plaque progression.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
    • 9 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends getting vitamin B12 tested and supplementing if deficient, as B12 deficiency can cause damage to the myelin coating around nerves, including cochlear nerves, and improve tinnitus severity scores.
    • 9 May 2026 · Calcium · neutral · YouTube ↗
      Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
    • 6 May 2026 · Calcium · neutral · X ↗
      Mentions calcium as a common deficiency.
    • 25 Apr 2026 · Niacin · neutral · YouTube ↗
      Mentions nicotinamide as an ingredient found in many NAD products and notes that niacinamide and nicotinamide are structurally the same.
    • 18 Apr 2026 · Niacin · recommends · X ↗
      Believes the niacinamide approach, along with the NAMPT/salvage pathway angle, is underrated and deserves more attention.
    • 12 Apr 2026 · Calcium · recommends · Facebook ↗
      Recommends adequate intake of calcium for bone strength.
  • Dr. Mark Hyman · Biotin · recommends
    • 6 Dec 2024 · recommends · YouTube ↗
      Recommends supplementing with biotin for hair follicle health and growth.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 30 Sep 2026 · Niacin · neutral · YouTube ↗
      Explains that pellagra, which killed 100,000 Americans, was a niacin deficiency, a B vitamin.
    • 14 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
    • 9 Sep 2026 · Vitamin C · uses · YouTube ↗
      Used intravenous vitamin C cocktails to help him detoxify and recover from chronic fatigue.
    • 31 Aug 2026 · Vitamin B6 · uses · YouTube ↗
      Optimized a child's nutrient status with vitamin B6, as the child had low B6 levels.
    • 20 Aug 2026 · Calcium · recommends · YouTube ↗
      Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C for immune system support and modulation.
    • 22 Jul 2026 · Vitamin C · uses · YouTube ↗
      Relies on Big Bold Health's HTB Immune Energy Chews, which deliver 1000mg of sprouted Himalayan tardy buckwheat, along with vitamin C, D, magnesium, and zinc, to support immune balance, resilience, energy, and focus.
  • Bryan Johnson · Biotin · neutral
    • 5 Sep 2024 · neutral · YouTube ↗
      Mentions biotin as an example of an ingredient that AG1 lists with a specific dose, but then contrasts it with other ingredients in proprietary blends where doses are not disclosed.
    • 5 Jun 2025 · Vitamin B12 · uses · YouTube ↗
      States that Blueprint essential capsules and soft gels are packed with key vitamins and minerals needed for strong bone health.
    • 5 Jun 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
    • 12 May 2025 · Calcium · recommends · YouTube ↗
      Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • Date not recorded · recommends · Website ↗
      Recommends adequate Biotin (Vitamin B7) for hair health, noting it is in the Blueprint stack.
    • Date not recorded · Calcium · recommends · Website ↗
      Recommends prioritizing calcium intake for postmenopausal women to help maintain bone density and reduce the risk of osteoporosis.
    • Date not recorded · Calcium · uses · Website ↗
      Bryan Johnson takes Calcium daily as part of his Longevity Mix, which supports healthy bones and teeth.
    • Date not recorded · Calcium · recommends · Source ↗
      Recommends continuing with calcium to support bone health during the follicular phase.
    • Date not recorded · Vitamin C · recommends · Website ↗
      Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
    • Date not recorded · Vitamin C · uses · Website ↗
      Bryan Johnson takes Vitamin C daily as part of his Longevity Mix, which is an antioxidant-rich essential vitamin that supports immune function and metabolic energy.
    • Date not recorded · Vitamin C · uses · Website ↗
      He uses Vitamin C, typically in a serum, in the morning for skin health.

RAL Summary

Members OnlyTier 4 for Energy

The tier 3 grade leans on animal studies and one uncontrolled blend study of biotin, a trace vitamin, while the main energy ingredients sit in the MetaPlus blend with no studies given, and the vitamins at their label doses show no clear human benefit for energy. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 58 of the 117 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system, Metabolic system

Combine with: To enhance the energy-boosting effects of Celsius Sparkling Cola and support overall vitality, consider combining it with L-Theanine to promote focused energy without jitters, or CoQ10 for cellular energy production. Magnesium can also be beneficial as it plays a crucial role in ATP synthesis, while adaptogens like Rhodiola Rosea or Ashwagandha could help manage stress and provide sustained energy throughout the day.

Possible side effects: No major side effects reported in the studies at these doses; high-dose niacin can cause fatigue, stomach upset and flushing, which does not apply to the 20 mg here.

Supplement Facts

Vitamin C 60 mg · Riboflavin 1.7 mg · Niacin 20 mg
Supplement Facts
Serving Size 355 mL
Servings Per Container 1
Amount Per Serving% Daily Value
Calories10
Total Carbohydrate2 g
Vitamin C60 mg
Riboflavin1.7 mg
Niacin20 mg
Vitamin B62 mg
Vitamin B126 mcg
Biotin300 mcg
Pantothenic Acid10 mg
Calcium50 mg
Chromium50 mcg
Sodium0 mg
MetaPlus Proprietary Blend1.81 g†
† Daily Value not established.

Other ingredients: Carbonated filtered Water, Natural Flavors, Sucralose, Citric Acid, Caramel color.

Barcode (UPC) 889392000283 · Label source: NIH label database · Report a label change

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Graded November 3, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.