Designer Wellness Stress Support Gummies Raspberry Sweet-Tea Flavored Review
Stress Support Gummies Raspberry Sweet-Tea Flavored is a dietary supplement from Designer Wellness, sold as gummies. The page lists 30 servings per container, with a net content of 60 gummies. The serving size is one gummy. The suggested use is 2 gummies daily or as directed by a healthcare professional. Each serving provides 20 calories, 5 grams of carbohydrate (listed as sugar), 13 mg of magnesium, and 5 mg of sodium. The botanical and non-botanical ingredients listed per gummy are 100 mg of L-Theanine, 100 mg of chamomile flower extract, and 100 mg of lemon balm leaf extract. The page states that Daily Value is not established for these ingredients. The warnings state to take only as directed and not to exceed the suggested dosage. Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. The product should be kept out of the reach of children, and it should not be used if the safety seal is damaged or missing. The allergen warning states that the product contains tree nuts (coconut). It is manufactured and packaged in a facility that may also process milk, soy, wheat, egg, peanuts, tree nuts, fish, and crustacean shellfish. The product is listed in the FDA Dietary Supplement Label Database under DSLD ID 295177. The page does not show a price or customer reviews.
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Study, Trial or Testing Result Summary
Members Only125 human studies · 82 improved
13 of these 125 human studies gave the ingredient by drip or inhaler, not by mouth.
Lemon balm has the strongest support here. These gummies give 100 milligrams per gummy, which reaches the studied amount at the four servings a day members are told to take. Pooled trials found lemon balm lowered anxiety and low mood scores more than placebo, though results varied [1]. In 100 healthy adults with emotional distress, 400 milligrams daily for 3 weeks improved mood, anxiety and stress [2]. L-theanine is present at a full dose. A single 200 milligram dose lowered a saliva stress marker after a stress test [3], and 4-week trials reduced stress symptoms [4][5]. However, its stress benefit across trials was modest and relied on weaker studies [6], and a pooled analysis found no anxiety benefit over placebo [7]. Chamomile and magnesium are present only in trace amounts, well below the studied doses. Chamomile helped generalized anxiety at 1500 milligrams daily [8], and magnesium studies used about 248 milligrams or more [9]. Animal and cell studies are never counted.
See all 125 studies →Hide the studies
- Pooling 52 trials with 4049 people, antioxidant supplements including magnesium improved depression scores (small effect for magnesium) and antioxidants overall improved anxiety.Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials…
- Across 31 placebo-controlled trials with 1168 people, a single 200 mg dose of L-theanine improved attention and reaction time, but its stress-lowering effect was modest and depended on studies with a high risk of bias, and anxiety results were inconsistent.Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
- In a review of randomized trials of diet changes for depression and anxiety around pregnancy, iron, zinc and magnesium together were not better than placebo for depression symptoms.Dietary interventions for perinatal depression and anxiety: a systematic review and meta-analysis of randomized controll…
- In 11 placebo-controlled studies, L-theanine combined with caffeine moderately improved alertness and attention switching within 2 hours of a dose, with calmness and anxiety outcomes not clearly shown.Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a s…
- In a network analysis of 29 trials of herbal treatments for anxiety, L-theanine did not reduce anxiety scores more than placebo.Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
- Across 12 randomized trials, chamomile improved generalized anxiety scores and sleep quality, but showed no clear benefit for general state anxiety or insomnia severity.Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep qualit…
- Pooled randomized trials of people with anxiety or depression symptoms found lemon balm lowered anxiety and depression scores more than placebo without serious side effects, though results varied widely between studies.The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and…
- A review of 22 studies found stress-related cortisol responses were most consistent with low-ratio matcha preparations and not with isolated compounds, with low-certainty evidence overall.A CE/TA-stratified systematic review and evidence map of matcha and green tea bioactives in endocrine stress regulation:…
- A review of 14 trials in women found magnesium combined with vitamin B6 reduced premenstrual anxiety but magnesium alone had no effect, and it did not lower stress in women with painful periods.The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women:…
- A review of 18 studies in people prone to anxiety found some trials reporting less anxiety with magnesium (about half in anxious and premenstrual groups) but no effect after childbirth, and the evidence was poor in quality.The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review.
- A review of 32 articles on magnesium and mental health found mostly positive results for depression but mixed results overall, with a possible benefit in stressed patients and a need for better trials.The Role and the Effect of Magnesium in Mental Disorders: A Systematic Review.
- A review of 21 studies found green tea reduced anxiety and improved memory and attention, with the cognitive benefits seen mainly when L-theanine and caffeine were taken together.Green tea effects on cognition, mood and human brain function: A systematic review.
- A review of 9 controlled trials suggested 200 to 400 mg a day of L-theanine may reduce stress and anxiety in people under stressful conditions, though larger and longer studies are needed.The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systema…
- A review of 11 randomized trials found L-theanine reduced psychiatric symptoms more than control in people with schizophrenia, anxiety disorders and ADHD.The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review.
- A review of lab and human studies found chamomile among ten plant remedies acting on the brain's calming (GABA) pathways, with anxiety-reducing effects and good safety.GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
- A review of 100 herb trials called chamomile promising for easing anxiety or depression with fewer side effects than standard medicines, but larger trials are needed.Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance.
- In 290 people with diabetes and insomnia, 2 months of magnesium, potassium or both significantly changed cortisol and melatonin levels and lowered insomnia severity compared with placebo.Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
- In 264 stressed adults with low blood magnesium, 300 mg magnesium daily for 8 weeks cut stress scores by about 42%, and adding vitamin B6 was no better overall but helped more in those with severe stress; there was no placebo group.Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A r…
- In 248 adults with cancer receiving infusion therapy, inhaling chamomile oil for a week did not significantly reduce anxiety; only ginger oil did.Efficacy of Inhaled Essential Oil Use on Selected Symptoms Affecting Quality of Life in Patients With Cancer Receiving I…
- In 183 older adults, inhaling chamomile or lavender oil for 30 nights reduced depression, anxiety and stress more than distilled water, with benefits lasting one month after.The effects of Lavender and Chamomile essential oil inhalation aromatherapy on depression, anxiety and stress in older c…
- In 182 patients with somatoform disorders, a 2-week herbal combination including lemon balm reduced anxiety and depression more than placebo, with the butterbur-containing version working best and no serious adverse events.Fixed herbal drug combination with and without butterbur (Ze 185) for the treatment of patients with somatoform disorder…
- In 159 first-time mothers in labor, Swedish massage with chamomile oil lowered anxiety and pain more than massage without oil or no massage.Investigating the effect of Swedish massage with chamomile oil on labor pain and anxiety of primiparous women: A clinica…
- In 157 adults with migraine in the emergency department, intravenous magnesium reduced pain about as much as two standard drugs, with no significant difference; this study did not test stress or calmness.MAGraine: Magnesium compared to conventional therapy for treatment of migraines.
- In 154 patients with acute coronary syndrome, inhaling chamomile oil for two nights lowered anxiety scores (5.2 points vs 1 point) plus blood pressure and heart rate more than placebo.Effects of aromatherapy with Matricaria chamomile essential oil on anxiety and hemodynamic indices in patients with acut…
- In 144 long-term a med users, magnesium aspartate compared with placebo did not significantly change the rate of stopping the drug; there were non-significant trends toward milder withdrawal and less rise in anxiety.Read the study on PubMed (9850822) →
- In 140 healthy volunteers, a daily spread with L-theanine, 5-hydroxytryptophan and GABA for 10 days improved memory, well-being and mood scores, but anxiety and depression scales did not change significantly.[Clinical evaluation of the efficacy of innovative spread of a given fatty acid composition enriched by adaptogens].
- In 126 adults with mild-to-moderate depression, 6 weeks of 248 mg magnesium daily improved depression scores by 6.0 points and anxiety scores by 4.5 points more than no treatment, with effects seen within two weeks.Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
- In 120 adults with major depression, a combination of magnesium orotate, probiotics and coenzyme Q10 for 8 weeks reduced self-rated anxiety and stress more than placebo.Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled tr…
- In 120 healthy young adults, a single 200 mg dose of L-theanine, with or without arginine, lowered the rise in a stress marker in saliva after a stress test compared with placebo.Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomi…
- In 120 nurses, inhaling chamomile-lavender essential oil over three work shifts gave lower anxiety scores (about 38) than the control group (about 56).The Effect of Music Therapy and Aromatherapy with Chamomile-Lavender Essential Oil on the Anxiety of Clinical Nurses: A …
- In 114 patients having gallbladder surgery, a magnesium sulphate injection before anaesthesia improved recovery quality scores by 8 points versus saline on the first day after surgery, mainly through better physical comfort and independence.Intravenously injected lidocaine or magnesium improves the quality of early recovery after laparoscopic cholecystectomy:…
- In 114 care home residents with Alzheimer's disease and agitation, melissa aromatherapy was no better than placebo or donepezil at 4 or 12 weeks, though all groups improved.A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitati…
- In 108 intensive care nurses, nightly chamomile-lavender oil massage for 4 weeks reduced fatigue and improved sleep quality more than placebo oil (sleep score fell from 10.41 to 4.69 vs 10.78 to 6.84).The Effect of Aromatherapy on Fatigue and Sleep Quality in Intensive Care Nurses: A Randomised Placebo-Controlled Trial.
- In 103 healthy active adults, the evening supplement containing magnesium L-threonate for two weeks did not clearly improve stress or sleep, while the morning ashwagandha and rhodiola group did.Modulating stress and sleep through a multi-compound dietary supplement: a randomized, double-blind, placebo-controlled …
- In 103 palliative care cancer patients, massage with Roman chamomile oil reduced anxiety and improved psychological symptoms and quality of life, while massage alone brought smaller changes that were not significant on most symptoms.An evaluation of aromatherapy massage in palliative care.
- In 100 adults over 51 with poor sleep, 320 mg magnesium daily for seven weeks improved sleep no more than placebo, though it lowered a blood marker of inflammation in those with high levels at the start.Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 ye…
- In 100 people doing strength-endurance training, 400 mg magnesium daily for 90 days improved heart rate variability measures of stress balance, while the control group showed no positive changes.[Long-term HRV analysis shows stress reduction by magnesium intake].
- In 100 moderately stressed adults, a single dose of magnesium with B vitamins, green tea and rhodiola raised relaxed-alert brain activity and reduced subjective stress, anxiety and mood disturbance during a social stress test versus placebo.A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects…
- In 100 chronically stressed healthy adults, a combination of magnesium, B vitamins, rhodiola and L-theanine for 28 days reduced stress scores more than placebo.Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy I…
- In 100 adults aged 18 to 45 with unsatisfying sleep, 2 g daily of magnesium L-threonate for 6 weeks improved overall cognition, reaction time, resting heart rate and heart rate variability versus placebo, but not general wellbeing or objective sleep measures.The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, doub…
- In 100 children aged six to nine having pulp therapy, inhaling chamomile aroma through a nebulizer reduced dental anxiety about as much as lavender and more than peppermint or no oil.The effects of lavender, chamomile and peppermint inhalation aromatherapy on dental anxiety in children: A randomized co…
- In 100 adolescent girls with premenstrual syndrome, 1200 mg daily of lemon balm for 3 menstrual cycles led to lower psychosomatic symptom, anxiety and sleep disorder scores than placebo.Effect of Melissa officinalis capsule on the mental health of female adolescents with premenstrual syndrome: a clinical …
- In 100 healthy adults with emotional distress or poor sleep, 400 mg daily of lemon balm extract for 3 weeks improved mood, anxiety, stress, wellbeing and quality of life scores.The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officin…
- In 96 adults with constipation-predominant irritable bowel syndrome, 1000 mg daily of a lemon balm, anise and rose formula for 4 weeks improved anxiety and depression scores compared with placebo.Effects of a traditional herbal formula containing Melissa officinalis, Pimpinella anisum, and Rosa damascena on anxiety…
- In 96 knee replacement patients, a valerian and lemon balm capsule taken from two nights before surgery cut shivering as well as clonidine, but the drop in anxiety was not statistically significant.Comparison of the Effects of a Melissa officinalis L. and Valerian Combination With Clonidine on Anxiety, Hemodynamic Ch…
- Adults with generalized anxiety who responded to 1500 mg daily chamomile extract and continued it for 26 weeks kept their symptoms lower than those switched to placebo, although relapse rates did not differ significantly.Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial.
- In 90 patients awaiting emergency orthopedic surgery, inhaled chamomile essential oil lowered anxiety and pain compared with a control group, though damask rose acted faster on anxiety.Comparison of the Effects of Aromatherapy With Damask Rose and Chamomile Essential Oil on Preoperative Pain and Anxiety …
- In 90 patients after colorectal cancer surgery, an aromatherapy massage blend containing chamomile lowered anxiety compared with a control group, but did not outperform plain massage for pain, fatigue or nausea.The effects of aromatherapy massage given to patients after colorectal cancer surgery on symptom management: A randomize…
- In 80 young adults, a single 200 mg dose of L-theanine before a virtual reality active shooter drill and mental challenge did not change saliva stress markers, heart rate or anxiety scores compared with placebo.Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality base…
- In a placebo-controlled trial of 80 breast cancer patients taking paclitaxel, 5 ml of chamomile oral solution three times a day did not reduce neuropathy or anxiety, but it improved sleep quality compared with placebo.Evaluation of the protective effect of chamomile oral solution on the incidence of neurotoxicity caused by paclitaxel in…
- In 80 patients with chronic stable angina, 3 g of lemon balm daily for 8 weeks reduced depression, anxiety, stress and sleep disturbance scores more than placebo.The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with c…
- In 76 patients in a cardiac care unit, inhaling a chamomile and bitter orange aroma for three nights lowered anxiety scores and helped heart rate recover more than in the comparison group.Effect of Citrus aurantium and chamomile aromas on anxiety and vital signs in cardiac care unit patients: A randomized c…
- In 72 healthy men, a herbal combination containing lemon balm taken for 4 days reduced self-reported anxiety during an acute stress test versus placebo, without changing the stress hormone cortisol response.Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men - An explorat…
- In 72 emergency patients with acute coronary syndrome, inhaling two drops of lemon balm oil twice for 10 minutes lowered stress and heart rate briefly versus placebo at some time points, but overall mean changes between groups did not differ significantly.Effect of aromatherapy with Melissa essential oil on stress and hemodynamic parameters in acute coronary syndrome patien…
- In 71 adults with benign heart palpitations (55 finished), 500 mg of lemon balm leaf extract twice daily for 14 days reduced palpitation episodes and the number of anxious patients more than placebo.Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of ef…
- In a randomized trial of 68 hemodialysis patients, inhaling lemon balm essential oil during dialysis three times a week for one month reduced anxiety and symptom burden more than inhaling sweet almond oil.The effectiveness of Melissa officinalis L. essential oil inhalation on anxiety and symptom burden of hemodialysis patie…
- In 66 children aged 2 to 5 having eye surgery, magnesium given through a drip during anaesthesia did not reduce confusion and agitation when waking up or pain compared with saline; 84% of the magnesium group and 79% of the control group had emergence delirium.Effect of magnesium supplementation on emergence delirium and postoperative pain in children undergoing strabismus surge…
- In 64 adults with impaired sleep taking a combination containing lemon balm, L-theanine, valerian and saffron for 6 weeks, sleep quality and sleep measures did not improve more than with placebo.Effect of a nutraceutical combination on sleep quality among people with impaired sleep: a randomised, placebo-controlle…
- In 61 adults with type 1 diabetes, a supplement containing magnesium plus saffron taken for 6 months did not differ from the same supplement without saffron except for lower triglycerides; the magnesium effect itself was not tested and diabetes distress did not differ between groups.Effect of Crocus sativus Extract Supplementation in the Metabolic Control of People with Diabetes Mellitus Type 1: A Dou…
- In 60 people with schizophrenia or schizoaffective disorder taking antipsychotics, 400 mg daily of theanine for 8 weeks reduced anxiety and positive symptoms more than placebo, and it was well tolerated.L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disord…
- In 60 adults with type 2 diabetes and depressive symptoms, 700 mg per day of lemon balm extract for 12 weeks reduced depression and anxiety scores more than a placebo flour, though sleep quality did not change.The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized d…
- Adults with mild to moderate generalized anxiety who took chamomile extract for 8 weeks had a larger drop in anxiety scores than those on placebo, though the study was small.A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for general…
- A re-analysis of a placebo-controlled chamomile trial found that adults with anxiety had greater reductions in depression scores on chamomile than on placebo, though this was an exploratory analysis.Read the study on PubMed (22894890) →
- In 52 men having robotic prostate surgery, magnesium given through a drip during surgery lowered blood pressure rises, cortisol (a stress hormone) over 24 hours, painkiller needs and later pain compared with saline.Beneficial Effects of Intravenous Magnesium Administration During Robotic Radical Prostatectomy: A Randomized Controlled…
- In 52 children with possible teeth grinding during sleep, a homeopathic lemon balm preparation given in 30-day phases reduced grinding scores more than placebo, while anxiety and sleep diary results did not change.Homeopathic medicine of Melissa officinalis combined or not with Phytolacca decandra in the treatment of possible sleep …
- In 49 overweight middle-aged adults, 350 mg of magnesium daily for 24 weeks lowered the amount of the stress hormone cortisol in 24-hour urine compared with placebo.Long-term magnesium supplementation improves glucocorticoid metabolism: A post-hoc analysis of an intervention trial.
- In 48 healthy adults, a single 200 mg dose of theanine did not significantly change mood, anxiety or alertness compared with placebo, though it did lower the blood pressure rise caused by caffeine and slowed reaction time on one task.Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and tog…
- In 46 adults with generalized anxiety disorder taking meds, 450-900 mg of L-theanine daily for 8 weeks did not reduce anxiety more than placebo, though it improved sleep satisfaction scores.L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled t…
- In 44 postmenopausal women with osteoporosis given zoledronate with or without 200 mg of oral magnesium daily for 3 months, magnesium did not significantly change pain, anxiety, depression or sleep quality 1 year later.Quantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
- In 43 stressed adults (35 analysed), a combination herbal supplement with magnesium and chromium for 15 days improved mood, trait anxiety and working memory under stress versus placebo.Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A r…
- In 40 people with schizophrenia or schizoaffective disorder taking 400 mg daily of theanine for 8 weeks, changes in blood BDNF and cortisol-to-DHEAS ratio were linked to symptom improvement, though this was an association analysis.Serum levels of brain-derived neurotrophic factor and cortisol to sulfate of dehydroepiandrosterone molar ratio associat…
- In 40 people with schizophrenia taking antipsychotics, 400 mg daily of L-theanine plus 50 mg pregnenolone for 8 weeks reduced negative symptoms and anxiety compared with placebo.Add-On Pregnenolone with L-Theanine to Antipsychotic Therapy Relieves Negative and Anxiety Symptoms of Schizophrenia: An…
- In 39 adults, drinking test matcha with a high theanine content lowered anxiety compared with placebo matcha, and the study notes that caffeine can counteract theanine's effect.Stress-Reducing Function of Matcha Green Tea in Animal Experiments and Clinical Trials.
- In 39 working adults with poor sleep, a 4-week RLX2 supplement containing L-theanine improved sleep quality scores compared with placebo, though the L-theanine dose was not stated.Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-C…
- In 38 women taking 200 mg magnesium oxide daily for two menstrual cycles, there was no effect in the first month, but in the second month fluid retention symptoms fell more than with placebo; anxiety was not reported as improved.Magnesium supplementation alleviates premenstrual symptoms of fluid retention.
- In 38 older adults in nursing homes, 20-minute aromatherapy massages with lavender, chamomile and rosemary oils three times a week for about seven weeks lowered anxiety and depression scores more than routine care alone.Effect of Aromatherapy Massage on Depression and Anxiety of Elderly Adults: a Randomized Controlled Trial.
- In 35 people with sleep problems, a magnesium (200 mg) plus melatonin coffee pod for 4 weeks improved sleep measures and anger-hostility scores more than placebo, though average sleep quality stayed poor.The effects of melatonin and magnesium in a novel supplement delivery system on sleep scores, body composition and metab…
- In 34 healthy adults aged 18-40, a single L-theanine drink reduced self-reported stress from a multitasking mental task compared with placebo, measured one hour after dosing.Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-…
- In 30 older adults with cognitive decline, two months of a combined nutraceutical containing L-theanine improved memory test scores and perceived stress compared with placebo; the L-theanine dose was not stated.Short-Term Impact of a Combined Nutraceutical on Cognitive Function, Perceived Stress and Depression in Young Elderly wi…
- In a 4-week placebo-controlled trial of 30 healthy adults taking 200 mg per day, L-theanine improved stress-related symptoms, sleep quality, and verbal fluency and executive function compared with placebo.Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized …
- In 30 healthy adults with moderate stress, 400 mg daily of theanine for 28 days reduced perceived stress and improved reaction time on a Stroop test, with some sleep changes, compared with placebo.Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Rando…
- In 24 women having hysterectomy, intravenous magnesium around surgery reduced meds needs but postoperative anxiety scores were similar to placebo.Magnesium infusion reduces perioperative pain.
- In 24 healthy volunteers, a single 600 mg dose of a lemon balm and valerian combination reduced anxiety during a laboratory stress task, but the highest dose of 1800 mg increased anxiety and all doses worsened some task performance.Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress.
- In 22 women with fibromyalgia, a Mediterranean diet enriched with 60 mg magnesium and 60 mg tryptophan for 16 weeks reduced trait anxiety, mood disturbance, eating disorder scores and body image dissatisfaction versus standard diet, but did not improve sleep.Psychological and Sleep Effects of Tryptophan and Magnesium-Enriched Mediterranean Diet in Women with Fibromyalgia.
- In 20 pharmacy students, 200 mg of theanine twice daily during a stressful practice period lowered self-rated stress and a stress-linked salivary enzyme compared with placebo.Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activ…
- In 20 pharmacy students over 10 days, drinking low-caffeine green tea providing about 15 mg of theanine daily lowered subjective stress and blunted the rise in a salivary stress marker compared with placebo tea.Anti-stress Effect of Green Tea with Lowered Caffeine on Humans: A Pilot Study.
- In 20 middle-aged adults, 7 days of low-caffeine green tea (which keeps more theanine) lowered a salivary stress marker and improved sleep quality compared with standard green tea.Reduced Stress and Improved Sleep Quality Caused by Green Tea Are Associated with a Reduced Caffeine Content.
- In 20 healthy young adults, a single 600 mg dose of standardised lemon balm extract improved sustained attention, but higher doses reduced alertness and some memory measures while calmness rose at the lowest dose.Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm).
- In 20 healthy young adults, a single 1600 mg dose of dried lemon balm leaf improved memory and increased calmness, while lower doses slowed some timed memory and visual processing tasks.Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemo…
- In 18 healthy volunteers, a single 600 mg dose of standardised lemon balm extract increased self-rated calmness and reduced alertness during a laboratory stress task compared with placebo.Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm).
- In 16 healthy volunteers, a single 200 mg dose of L-theanine did not reduce anticipatory anxiety under experimentally induced anxiety, though it showed some relaxing effect at rest.Read the study on PubMed (15378679) →
- In 16 healthy volunteers, sucking a lozenge containing lemon balm with lavender, hops and oat increased brain wave patterns linked to relaxation compared with placebo, though this was an electrical measure rather than a clinical outcome.Effects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activity of volun…
- In 14 adults under mental stress, L-theanine blunted the blood pressure rise in high-responders and reduced tension-anxiety mood scores compared with placebo; the dose was not stated.Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses.
- In a placebo-controlled study of 12 adults given a mental arithmetic stress task, L-theanine reduced heart rate and salivary immunoglobulin A responses to stress compared with placebo.L-Theanine reduces psychological and physiological stress responses.
- In 12 elite wrestlers, 3 mg/kg of L-theanine combined with caffeine improved performance and reduced anxiety compared with placebo, while L-theanine alone was not reported to show a clear anxiety benefit.Performance-enhancing effects of caffeine and L-Theanine among Iranian elite wrestlers: a focus on cognitive and specifi…
- In nine children with autism, a high L-theanine tea showed only sporadic improvements in balance and sleep, while a high GABA tea gave more consistent gains; the L-theanine dose was not stated.A double-blind, placebo-controlled, randomised-designed GABA tea study in children diagnosed with autism spectrum condit…
- In stressed adults with low magnesium, 8 weeks of 300 mg magnesium daily, with or without vitamin B6, significantly improved anxiety, depression and quality of life scores from baseline, mostly in the first 4 weeks; there was no placebo group.Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post…
- In fibromyalgia patients given 100 mg magnesium daily for 1 month, overall stress scores did not differ from placebo, but those with mild or moderate stress improved significantly and pain also decreased.Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinica…
- In a crossover study of moderately stressed healthy adults, a single 200 mg dose of theanine increased frontal alpha brain wave activity and lowered salivary cortisol more than placebo after a stress task.A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWav…
- In an 8-week placebo-controlled trial, a combined walnut peptide and theanine supplement improved self-reported sleep quality and sleep duration in adults with sleep disturbance; the theanine dose alone was not reported.Walnut peptide and theanine combination ameliorates sleep disorders: a multi-species study including a human trial.
- In an eight-week open-label phase of a chamomile extract trial for generalized anxiety disorder, patients who expected the treatment to work had greater reductions in anxiety scores and more clinical responses, while those with higher side-effect expectations reported more side effects.Specific expectancies are associated with symptomatic outcomes and side effect burden in a trial of chamomile extract fo…
- In two double-blind placebo-controlled crossover studies of healthy young adults, a standardized lemon balm drink or yoghurt generally improved mood and/or cognitive performance, though some doses showed behavioral costs and effects varied by food type.Anti-stress effects of lemon balm-containing foods.
- In a double-blind, placebo-controlled crossover study, 87% of people taking a lemon balm phytosome extract reported better sleep quality compared with 30% on placebo, and their insomnia scores dropped significantly.Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, a…
- In 105 burn patients, three bedtime massages with lavender and chamomile oil over one week reduced anxiety and improved sleep quality compared with the control groups.The effect of aromatherapy massage with lavender and chamomile oil on anxiety and sleep quality of patients with burns.
- In 80 patients with alcoholic delirium, adding magnesium sulfate to standard sedation shortened delirium to 3.4 days versus 5.4 days with standard care alone, and combining it with dexmedetomidine (a sedative) shortened it further to 1.1 days; this was not a study of stress or calmness in healthy people.Use of a combination of dexmedetomidine and magnesium sulfate as a multimodal approach to the treatment of alcoholic del…
- In 60 people after open-heart surgery, 500 mg magnesium daily for five days led to lower anxiety and depression and better sleep quality than routine care alone.Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart sur…
- In a quasi-experimental study of 59 women aged 65 and older, aromatherapy massage with lavender, Roman chamomile and sandalwood oils reduced itching and stress compared with a sandalwood-only control massage, with no adverse effects.Aromatherapy Massage for Relief of Pruritus and Stress in Older Women.
- In 36 people shown stressful film clips, a single 200 mg dose of L-theanine sharpened one type of visual attention and altered another, while counteracting the effects of caffeine when taken together.Caffeine and theanine exert opposite effects on attention under emotional arousal.
- In a small controlled study of 36 Korean elderly women, 20-minute aromatherapy massages with chamomile and other oils, three times a week for about seven weeks, improved anxiety and self-esteem compared with the control group.Effects of aromatherapy massage on anxiety and self-esteem in korean elderly women: a pilot study.
- In 18 college archers given L-theanine or a placebo before a competition, the L-theanine group reported lower pre-competition anxiety and lower saliva stress markers at some time points.Effects of supplement L-theanine on cognitive anxiety, salivary alpha-amylase, and cortisol in archery competition.
- In an open-label study with no control group, about 58 percent of adults with moderate to severe generalized anxiety responded after up to 8 weeks of 1500 mg daily chamomile extract.Short-term open-label chamomile (Matricaria chamomilla L.) therapy of moderate to severe generalized anxiety disorder.
- In 179 adults with anxiety disorder, 1500 mg of chamomile extract daily for 8 weeks reduced anxiety, and those who also had depression showed a larger drop in depression scores.Read the study on PubMed (31808709) →
- In 45 adults with anxiety, those whose symptoms improved on chamomile extract showed rising morning cortisol levels, though the study had no placebo group.An exploratory study of salivary cortisol changes during chamomile extract therapy of moderate to severe generalized anx…
- In 34 children with Tourette syndrome and anxiety, an L-theanine and vitamin B6 supplement reduced tics and anxiety more than psychoeducation alone in an open-label trial, though both groups improved and placebo-controlled trials are still needed.Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disor…
- In an open-label study of 20 adults with major depression, 250 mg of L-theanine daily added to their medication for 8 weeks was linked to lower depression, anxiety and sleep scores and better attention and memory tests, though there was no placebo group.Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
- In nine healthy men, 14 days of magnesium aspartate led to lower cortisol levels during an hour of exercise and the usual exercise rise in cortisol and aldosterone was not seen.Plasma aldosterone, cortisol and electrolyte concentrations in physical exercise after magnesium supplementation.
- In a large observational study of 8058 women in labour, aromatherapy including chamomile was associated with reduced anxiety, fear and pain, with chamomile and clary sage judged effective for pain, and only mild side effects reported.The use of aromatherapy in intrapartum midwifery practice an observational study.
- In a retrospective review of 3,252 hospitalized psychiatric patients, those prescribed a herbal combination containing lemon balm had significantly fewer a med prescriptions than matched controls, with comparable clinical effectiveness.Read the study on PubMed (31985131) →
- In a survey of 1,388 older adults, higher dietary magnesium intake was linked to less cognitive decline, including among those with impaired sense of smell; stress or calmness was not measured.The effect of dietary magnesium intake on cognitive decline related to olfactory impairment in older adults: a cross-sec…
- In 141 middle-aged adults, those with better diets had higher magnesium intake and better attention scores, and higher diet scores went with fewer mood problems and lower perceived stress, but the two diet groups did not differ significantly on mood or stress.Self-Reported Diet Quality Differentiates Nutrient Intake, Blood Nutrient Status, Mood, and Cognition: Implications for …
- In 111 critically ill children in an intensive care unit, a gentle massage with a 1% blend of lavender, chamomile and neroli oils was followed by lower distress and lower heart rate and anxiety scores, though pain and oxygen levels did not change clearly.Aromatherapy massage seems effective in critically ill children: an observational before-after study.
- In a survey of 73 Brazilian nursing students, chamomile was among the most-used plants for calming and anxiety, and users reported symptom improvement, though stress differed between groups and symptoms were more common among plant users.Depressive symptoms, anxiety, stress, and the use of medicinal plants by nursing students.
- In 49 patients with long-term low parathyroid hormone after surgery, calcium and magnesium supplement use affected symptom scores in a dose-dependent way, but the abstract ties the rise in depression and anxiety scores to calcitriol, not magnesium.The Influence of Conventional Treatment on Symptoms and Complaints in Patients With Chronic Postsurgical Hypoparathyroid…
- In a survey of psychiatric outpatients in Serbia, many used chamomile tea to relieve anxiety and psychotic symptoms, and some reported side effects when combining herbs with prescribed psychiatric medicines.An epidemiological study on herbal product self-medication practice among psychotic outpatients from Serbia: A cross-sec…
- In people with dementia and insomnia, massage with single essential oils changed some sleep-related body chemicals in different ways, and a blend containing chamomile, lavender and valerian raised one serotonin-related marker the most.Differences in Neurotransmitters Level as Biomarker on Sleep Effects in Dementia Patients with Insomnia after Essential …
Review Totals and Summary
Members OnlyWhat buyers say
**Overall picture:** The feedback supplied does not describe Designer Wellness Stress Support Gummies Raspberry Sweet-Tea. Nearly all of it is enthusiastic praise for a different product, "Golden Canna Farms CBD Gummies," and it reads like promotional posts for a free-trial offer. It tells you very little about the gummies you are considering. **What buyers say it did for them:** The glowing claims are all about the Golden Canna Farms product, so they should not be credited to this one. Those writers describe relief from anxiety, aches and energy loss, with lines like "the product is a miracle worker" and "all my chronic pain has vanished!" Some claim to have stopped other medications, which is an extraordinary claim that nothing here supports. Other posts are vague, such as "worked for me!" and "crazy results to far," and do not name any benefit tied to Designer Wellness. **What they complain about:** No complaints appear anywhere in the material. Nobody mentions side effects, a failed result or a bad experience. The absence of criticism is itself a warning sign, since the posts read as uniformly promotional and some refer to "free samples" and signing up for a "trial." **Taste, smell, pill size or form:** Nothing is said about raspberry sweet-tea flavor, scent, texture or gummy size. Anyone wanting to know whether it tastes good will find no answer here. **Value for money:** The only price-related remarks concern free samples and trial offers for the other product, such as "Nice of her to give out these free samples too!" Nothing speaks to the cost, serving count or worth of the Designer Wellness gummies. I left out no other product forms, because none appear, but any capsule or powder feedback would have been excluded anyway. **Who it seems to suit and who it did not:** The reviews give no usable guidance on this. Writers mention anxiety, depression, aging aches and fatigue, but only in connection with the other brand. One writer says they have "tried everything" and nothing helped, which is not evidence about this product. Nobody describes who it did not suit. **Bottom line:** I would not base a buying decision on this feedback. To judge the Designer Wellness gummies, look for reviews that name the product, describe the flavor and say how long the writer used it.
Biohacker Summary
Members Only10 of 10 recommend it
Lemon balm, the main ingredient, drew a mostly favorable but thin response: four of the ten panelists recommend it, one is neutral, and the other five did not speak about it. Those who recommend it value it for helping the body relax and for a calming, sedative-like effect, and one says it works well when quitting coffee. One also recommends it for preventing recurrent cold sores. The forms they mention are tea, often with mint and sage, or paired with chamomile, and no one gave a dose. The neutral voice notes there is little long-term research on lemon balm for sleep and anxiety, that results are hard to repeat because products vary, and that no one follows people after they stop. Magnesium is a smaller ingredient in this product, and most of the panel takes or recommends it for sleep, with several using 400 milligrams of the threonate form before bed, though one cautions that evidence for sleep is not consistent.
See all 10 biohackers →Hide the biohackers
Dr. Mark Hyman · Lemon Balm · recommends
- Recommends lemon balm as an ingredient in Besper that helps the body relax.
- Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
- Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
- Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
- Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
- Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
- Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
- Recommends correcting nutrient deficiencies with magnesium.
- Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
- Has recommended Magnesium Breakthrough from Bio Optimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
- Recommends Magnesium Breakthrough Advance 10 from Bio Optimizers, which contains 10 bioavailable forms of magnesium, as it plays a critical role in sleep recovery, stress regulation, and muscle function, and has become part of his evening routine, especially during periods of travel, training, and higher stress.
- Mentions that ingredients like lemon balm in Vesper help the body relax.
- Recommends adaptogenic herbs like ashwagandha, particularly at night, rhodiola, lemon balm, and catclaw for stress relief.
- Recommends lemon balm as an herbal supplement for deep sleep and relaxation, especially for those who are tired, wired, and stressed.
Siim Land · Lemon Balm · neutral
- Notes that there isn't much long-term research on substances like lemon balm for sleep and anxiety, and replication is a problem due to varying product formulations. He also points out a lack of follow-up on people after they discontinue supplementation.
- States that Magnesium can be a useful addition for some people for sleep.
- Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
- Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
- Lists Magnesium as one of 15 supplements backed by human studies.
- States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
- Lists seafood and pumpkin seeds as sources of Magnesium.
- Thinks magnesium has some of the strongest evidence and is worth considering.
- Mentions getting a 'glycine + chamomile tea buzz too hard', implying a connection to sleep or relaxation.
- Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
- Notes that Boron reduces calcium/magnesium loss.
- Notes that magnesium is important for activating thiamine into its more biologically active form, and a magnesium deficiency can impair blood sugar regulation even with adequate thiamine intake.
- Recommends having chamomile tea in the evening as it has autophagy-regulating effects and is part of his perfect evening tea.
- Warns that chamomile is ludicrous for people with severe mental health challenges, as it's not potent enough, but might be interesting for those with very low-grade anxiety.
Dr. Eric Berg · Lemon Balm · recommends
- Recommends lemon balm tea as it works well when quitting coffee.
- Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
- Notes that magnesium could also be a factor in preventing muscle cramps.
- Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
- Recommends increasing magnesium to restore balance and support healthy blood pressure.
- Dr. Eric Berg suggests that magnesium could help support deeper, more restful sleep.
- Recommends Magnesium Glycinate, noting that the combination of magnesium and glycine is helpful for connective tissue, sleep, and reducing stress.
- Recommends taking magnesium 90 minutes to 2 hours before bedtime to support better sleep.
- Suggests that magnesium glycinate can help support the missing 'break pads' on the nervous system, which contribute to constant pain.
- Taking 400 mg of magnesium glycinate daily may also help support brain health during menopause.
- Warns against magnesium oxide because it is poorly absorbed, with only about 4% absorption, and can cause diarrhea, despite being commonly used in research and supplements due to its low cost.
- Dr. Eric Berg recommends Chamomile Tea to help reduce kidney and gallstones.
- Recommends adding lemon balm tea in the morning as another awesome thing when transitioning off coffee.
- Recommends lemon balm tea as one of the best weight loss drinks, noting it contains rosmarinic acid which increases GABA.
Thomas DeLauer · Lemon Balm · recommends
- Recommends chamomile and lemon balm as hugely beneficial for a sedative-like effect that can make one feel calmer, especially if tart cherry juice is avoided due to sugar content.
- Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
- Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
- Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
- Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
- Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
- Recommends taking some magnesium glycinate tonight to help calm down and sleep.
- Mentions that magnesium in pumpkin seeds relaxes bronchial smooth muscle.
- Compares magnesium content, stating bananas have 32mg and pumpkin seeds have 156mg per ounce, a 5x difference.
- Recommends Magnesium glycinate, stating that 200-400mg elemental helps with sleep as glycine cools the body and magnesium calms.
- Notes that magnesium sits on the NMDA receptor and regulates excitatory transmission, in the context of feeling stressed.
- Recommends a simple bag of chamomile tea in a nighttime drink, noting it acts as a sedative to help fall asleep.
- Recommends chamomile and lemon balm as hugely beneficial for a sedative-like effect that can make one feel calmer, especially if tart cherry juice is avoided due to sugar content.
- Recommends chamomile in supplement form for sleep, noting its potent, tranquilizer-like effect that binds to Gaba A, helping people wind down and relax a few hours before bed.
Dave Asprey · Lemon Balm · recommends
- Recommends using lemon balm to aggressively prevent recurrent cold sores.
- Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
- Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
- States that magnesium can affect how the body responds to a supplement.
- Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
- Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
- Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
- Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
- Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
- Dave Asprey recommends adding 300 or 400 mg of magnesium glycinate before bed to improve deep sleep quality, support growth hormone release, and burn visceral fat while asleep.
- Mentions magnesium glycinate as one of the extensively researched ingredients in Kill Switch that helps with natural sleep.
- Recommends using lemon balm to aggressively prevent recurrent cold sores associated with herpes simplex 1, especially for those at risk of Alzheimer's.
Ben Greenfield · Lemon Balm · recommends
- Ben recommends lemon balm as an ideal herb for making tea, especially when combined with hot water, mint, and sage. He considers mint and lemon balm to be the two quintessential herbal medicines for tea.
- Uses magnesium during surgery because it is neuroprotective.
- Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
- Mentions magnesium as part of a bare-minimum protocol.
- Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
- Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
- Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
- Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
- Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
- Recommends taking magnesium as a co-factor to increase vitamin D absorption.
- Notes a new study indicating that magnesium is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
- Suggests using chamomile as a compound to help shut down hardwired dopamine firing pathways for those with ruminating thoughts at night.
- Ben Greenfield recommends chamomile as an herbal supplement for insomnia.
- If Ben Greenfield wakes up in the wee hours, he uses lemon balm to increase his gamma amino butyric acid (GABA) production.
Dr. Rhonda Patrick · Magnesium · neutral
- Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
- Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
- Mentions magnesium as an important nutrient component for testosterone.
- Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
- States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
- States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
- Recommends considering magnesium to improve mood.
- Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
- Mentions that kale delivers magnesium, a micronutrient many diets fall short on.
- Recommends Magnesium, stating it is a cofactor for over 300 biological processes, including DNA repair, energy production, and sleep regulation.
- Recommends Chamomile as a sleep supplement that promotes relaxation and reduces nighttime awakenings, offering meaningful improvements to sleep quality.
- Mentions chamomile as one of the calming things that can be helpful for people who need a little bit of calming and relaxation to promote sleep, even if it doesn't technically do anything on the sleep side.
- Recommends drinking chamomile tea at night before bed for sleep quality, as it is rich in apigenin and has some evidence to support its benefits.
Andrew Huberman · Magnesium · neutral
- Discusses Magnesium Threonate as a tool for falling asleep.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
- Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
- He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
- Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of magnesium L-threonate before bed for sleep.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Mentions chamomile extract as one of the clinically supported ingredients that can help you fall asleep, stay asleep, and wake up feeling more refreshed, and he has worked with AG1 to create a product that includes it.
- Mentions Chamomile extract as a clinically supported ingredient that can help people fall asleep, stay asleep, and wake up feeling more refreshed.
- States that chamomile extract is a clinically supported ingredient that can help one fall asleep, stay asleep, and wake up feeling more refreshed.
- Mentions chamomile extract as one of several clinically supported ingredients that can help people fall asleep, stay asleep, and wake up feeling more refreshed.
Bryan Johnson · Magnesium · uses
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of magnesium L-threonate before bed for sleep.
- He takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of magnesium threonate before bed for sleep.
Peter Attia · Magnesium · neutral
- Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
- Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
- Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
- Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
- Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
- Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
- Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
- Takes magnesium as a straightforward supplement.
- Mentions that magnesium intake is often super low and impactful on testosterone levels.
- Discusses the important roles of magnesium in the body, how to determine if one might be deficient, the prevalence of magnesium deficiency, and its potential cognitive benefits.
RAL Summary
Members OnlyTier 4 for Stress and Calm
The review feedback describes a different product, Golden Canna Farms CBD Gummies, in apparently promotional posts, so it says nothing about these Designer Wellness gummies and has been set aside. Its reviews are set aside, so it is graded on its studies alone. Human studies support Lemon Balm (17 of 24 human studies showed an improvement), but there are not yet enough reviews to confirm it (0).
Take 4 servings a day (8 gummies) to match the dose that worked in the studies.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 17 of the 125 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Nervous system
Combine with: To strengthen the stress and calmness benefits, pair this with magnesium glycinate for nervous system relaxation and muscle tension, and with rhodiola or a B-complex for resilience to stress and fatigue. Taking glycine or a little extra L-theanine in the evening can support winding down and sleep quality. If your real goal is better blood flow, add L-citrulline or beetroot extract for nitric oxide production, and consider omega-3 fish oil, CoQ10, or nattokinase for broader cardiovascular support. Check with a healthcare provider first if you take blood pressure, blood thinning, thyroid, or sedative medications, because ashwagandha can interact with them.
Possible side effects: Lemon balm trials reported no serious side effects. No side effects were reported for this product.
Supplement Facts
Total Carbohydrates 5 g · Magnesium 13 mg · L-Theanine 100 mg
| Calories | 20 | |
| Total Carbohydrates | 5 g | |
| Magnesium | 13 mg | |
| Sodium | 5 mg | |
| L-Theanine | 100 mg | † |
| Chamomile flower extract | 100 mg | † |
| Lemon Balm leaf extract | 100 mg | † |
Other ingredients: Tapioca Syrup, Cane Sugar, Water, Citric Acid, Coconut Oil, Carnauba Wax, Fruit and Vegetable Juice, Natural Flavors, Pectin, Sodium Citrate.
Directions: Suggested Use: 2 gummies daily or as directed by a healthcare professional.
Barcode (UPC) 844334012731 · Label source: NIH label database · Report a label change
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- Supplements for Stress and Anxiety Relief: What the Evidence SupportsArticle · Oct 26, 2026
- The Four Pillars of Good Health: Diet, Exercise, Sleep and StressArticle · Mar 17, 2026
Graded November 7, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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