PEScience Smart Mass Amazing Gourmet Chocolate Review

Smart Mass is presented by PEScience as a lean mass gainer and meal replacement, also called the Clean Weight Gainer. The page says most mass gainers are mostly sugar and maltodextrin, while Smart Mass is built around real macros, slow-digesting carbohydrates, and a whey and casein protein blend. Each serving is listed at 225 calories with 25 grams of protein, 25 grams of carbohydrate, and 5 grams of fat, and the page says it is maltodextrin free. The product is offered in Gourmet Chocolate and Gourmet Vanilla flavors, with 14 servings per bag, and is listed as gluten free and third-party tested. The Nutrition Facts panel gives a serving size of one scoop (58 g), with 7 grams of sugar, 6 grams of which come from added Palatinose sugar, and 1 gram of fiber. The page explains that the protein blend combines fast-digesting whey and slow-digesting casein, which it says suits post-workout use, bedtime, or meals. Its carbohydrates come from pea starch, isomaltulose (Palatinose) and whole oat bran, which the page presents as a slower alternative to simple sugars and maltodextrin. The formula includes a digestive enzyme blend that the page says supports digestion of protein, fats and carbohydrates, including lactose. The page states that the product contains lactose in an amount that may be tolerable for some people with lactose intolerance, and it lists milk, coconut and soy as allergens. Suggested use is one scoop mixed with 16 ounces of cold water, or with milk or a dairy-free alternative for more calories and protein. The page notes that the product contains no added fats, so users may blend in ingredients such as frozen fruit, quick oats, Greek yogurt, avocado, nut or seed butters, or olive oil. The product page describes Smart Mass as suited to people who struggle to gain weight, bodybuilders in the off season, and older adults with unintentional weight loss. It also says the product can serve as a meal replacement, and that its per serving cost is low relative to its protein content. The page includes a technical write-up by registered dietitian Gavin Van De Walle, who discusses the differences between whey and casein, the role of carbohydrate sources, and the purpose of digestive enzymes in mass gainers. The write-up cites published research on these topics. The page also notes that a packet format is used for the first batches and that tubs may come later.

Product Focus: Muscle and StrengthAlso covers:Digestion
Tier ⓘ
Tier 4 · Rank 8
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 8 within Tier 4 for Muscle and Strength; 46 of 88 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
57 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
82% of 1,736
Biohacker Mentions
9 of 10
Cost per month
$54

Study, Trial or Testing Result Summary

Members Only70 human studies · 18 improved

4 of these 70 human studies gave the ingredient by drip, not by mouth.

70 human studies18 improved38 no effect749,896 people studied

This mass gainer is mainly a milk and whey protein blend with starch and other carbohydrates, but no studies on those main ingredients were provided, so this summary covers only the added vitamins and minerals. Their amounts are not shown on the label, so it is unknown whether any reaches a studied dose. Vitamin A alone was not shown to build muscle in a review of 16 trials [1]. One small trial saw a muscle gain with a mix that included vitamin A [2]. Calcium showed no link to muscle mass or strength in a review of 45 studies [3], and did not change muscle performance in teenage girls [4]. Vitamin C, alone or with vitamin E, neither helped nor hurt lean mass or strength gains from training [5]. In some trials, vitamin C with vitamin E blunted training gains [6]. Iron helped strength in one small trial of volleyball players [7], but a larger placebo trial found no gain in muscle mass or strength [8]. Animal and cell studies are never counted.

See all 70 studies →Hide the studies

Review Totals and Summary

Members Only1,736 reviews · 82% positive
1,736 reviews · Amazon 1,395 · PEScience 341
82% positive7% neutral11% negative

Buyers rate this powder very highly: about 1,736 ratings across the stores, and the written feedback is almost all praise. The written comments are few, so treat the themes below as a small sample. **What buyers say it did for them:** Several people describe real progress with weight and muscle. One says "I've felt muscle being built and seen weight being gained." Another calls it "Helping me get to my goal weight!" and has bought it four or five times. One reviewer bought it for her mother after knee replacement surgery, when the mother was struggling to eat enough to keep her weight up and support recovery. **What they complain about:** There is almost nothing. The one criticism is package size: a buyer wishes it "would come in a 10lb bag again like it used too." Another reviewer notes that other brands have more calories, though she still found this one had the best macro and nutrient profile. No written review complains about taste, texture, mixing or side effects. Reviewers also don't discuss digestive problems, aftertaste or lactose, so those points are simply not covered. **Taste, mixing and feel:** Taste is the most common theme. One reviewer says "Great taste not like the chalky mass gainers other companies have." The mother in the knee-surgery story loves the taste, and the formula "mixes well." One buyer says it is "so clean, doesnt leave me bloated." The chocolate flavor gets a direct mention from a reviewer who "really enjoyed the chocolate taste." Her husband, who normally only drinks vanilla shakes, also loved it. Some people drink it as a shake, and one stirs it into oats for breakfast. The store Q&A adds that the digestive enzymes are plant-derived and that it is gluten free. **Value for money:** Reviewers do not discuss price or cost per serving, so there is nothing to report on value. The only related points are the wish for the larger 10lb bag and the remark that competitors offer more calories. One buyer also liked the free samples added to her box. **Who it seems to suit:** It suits people who want to gain weight without a heavy or chalky shake. Reviewers include a competitive bodybuilder's mother who needed calories during recovery, people working toward a goal weight, and repeat buyers who call it "By far greatest mass gainer ive ever had." The balance of protein, carbohydrate and fat is praised, and the page summaries say it fits people who want calories without a dirty bulk. **Who it may not suit:** Anyone who wants the highest calorie count per serving may find other brands offer more. Anyone who wants a large bulk bag may be disappointed that the 10lb size is no longer sold. Beyond those two points, no group of buyers reported being let down. Only the powder is covered here. No reviews of other forms such as gummies or capsules were included.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

The product has no main ingredient with panel statements, so the panel's comments are all about smaller ingredients in this product. Vitamin C drew the most attention: most of the panel recommend it, mainly to support collagen for skin, joints and connective tissue, with one suggesting it be taken with collagen about an hour before a workout and another naming 500 mg to 1 g as a dose, while one cautioned that high doses might blunt the benefits of exercise. Calcium was backed by two of them for bone health, one giving 1,000 to 1,200 milligrams a day, though another warned that calcium alone cannot fix bone loss. Iron got mixed views: one said it is among the best supported nutrients for thinking and memory, another warned that too much raises harmful aging cells, and one said he stopped after years of supplements failed to raise his levels. Vitamin A was mostly mentioned neutrally, with one recommending the real animal form for people who cannot convert plant sources.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Iron · neutral
    • 30 Oct 2026 · neutral · YouTube ↗
      Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 25 Oct 2026 · Calcium · warns · YouTube ↗
      Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 24 Oct 2026 · Vitamin A · neutral · YouTube ↗
      Notes that low vitamin A can lead to dry eyes, dry mouth, and night vision issues.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 18 Oct 2026 · neutral · YouTube ↗
      Mentions that grass-fed liver has heme iron, the most bioavailable form of iron that prevents anemia.
    • 18 Oct 2026 · Vitamin A · neutral · YouTube ↗
      Mentions that grass-fed liver has the active form of vitamin A, called retinol, which is important for eyes, thyroid, immune system, and skin.
    • 17 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Highly recommends taking natural food vitamin C, about 500 mg, at the first sign of a cold.
    • 10 Oct 2026 · warns · Podcast ↗
      Dr. Berg warns that too much iron can be damaging to the body and advises focusing on food sources to avoid overconsumption.
    • 10 Oct 2026 · Calcium · warns · Podcast ↗
      Dr. Berg includes calcium carbonate among the synthetic supplements to avoid.
    • 10 Oct 2026 · Vitamin A · warns · Podcast ↗
      Dr. Berg warns that synthetic vitamin A can cause problems, including competing with vitamin D, increasing the risk of birth defects during pregnancy, and increasing the risk of bone fractures, recommending food sources like egg yolks and cod liver oil instead.
    • 3 Oct 2026 · warns · YouTube ↗
      Warns that too much iron, especially the ferrous sulfate or fumarate type found in many supplements, is corrosive and oxidizing, can mess with the liver, and create inflammation, noting that males have no natural way to excrete excess iron.
  • Ben Greenfield · Vitamin C · recommends
    • 29 Oct 2026 · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 21 Oct 2026 · Vitamin A · neutral · Instagram ↗
      Notes that Vitamin A is a fat-soluble vitamin that supports healthy skin cell turnover.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 24 Sep 2026 · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 25 Aug 2026 · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 9 Jul 2026 · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
    • 9 Jul 2026 · Iron · recommends · YouTube ↗
      Recommends testing for and replenishing iron if levels are low, as it can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
    • 29 May 2026 · Iron · neutral · Facebook ↗
      Notes that one can eat iron-rich foods or supplement with iron, but still feel exhausted if iron is not the missing piece, emphasizing that focusing on a single mineral in isolation can support a number on a lab test rather than the system itself.
    • 9 May 2026 · Calcium · neutral · YouTube ↗
      Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
    • 6 May 2026 · Iron · neutral · X ↗
      Mentions iron as a common deficiency.
    • 6 May 2026 · Calcium · neutral · X ↗
      Mentions calcium as a common deficiency.
    • 16 Apr 2026 · Iron · recommends · YouTube ↗
      Recommends a nutritious diet including iron, as it is critical for brain development.
    • 12 Apr 2026 · Calcium · recommends · Facebook ↗
      Recommends adequate intake of calcium for bone strength.
    • 12 Mar 2026 · Vitamin A · recommends · YouTube ↗
      Recommends vitamin A derivatives like retinol for targeting wrinkles and laxity, as they work deeper without aggravating the surface.
  • Siim Land · Vitamin C · recommends
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 14 Oct 2026 · Iron · neutral · Instagram ↗
      Mentions that iron is a mineral necessary for making collagen.
    • 30 Sep 2026 · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 30 Sep 2026 · Calcium · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 30 Sep 2026 · Vitamin A · neutral · X ↗
      Lists liver and carrots as sources of Vitamin A.
    • 6 Sep 2026 · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 3 Sep 2026 · Iron · warns · YouTube ↗
      States that excess iron promotes oxidative stress and inflammation, which increases heart disease risk.
    • 14 Aug 2026 · Calcium · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 27 Jul 2026 · neutral · X ↗
      Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
    • 27 Jul 2026 · neutral · X ↗
      States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
    • 27 Jul 2026 · recommends · YouTube ↗
      States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
    • 9 Jul 2026 · neutral · YouTube ↗
      Mentions vitamin C in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
    • 4 Jul 2026 · uses · YouTube ↗
      Was found to be vitamin C deficient by True Health and Mayo Clinic tests, and now addresses this by eating one extra kiwi fruit daily.
  • Thomas DeLauer · Vitamin C · recommends
    • 26 Oct 2026 · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 4 Oct 2026 · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 29 Sep 2026 · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 18 Sep 2026 · Iron · neutral · Facebook ↗
      Compares iron content in spinach (2.7mg) and beef (2.6mg), but emphasizes that beef's heme iron absorbs at about 25%, while spinach's non-heme iron absorbs at 2-8%.
    • 18 Sep 2026 · Calcium · neutral · Facebook ↗
      Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
    • 29 Aug 2026 · neutral · Instagram ↗
      States that collagen synthesis is vitamin C dependent, in the context of glowing skin.
    • 25 Aug 2026 · recommends · YouTube ↗
      Recommends Vitamin C for sleep, noting that intake in the range of 125 to 200 mg per day is associated with a lower risk of sleep disorders and sleep apnea, with the benefit plateauing beyond this range.
    • 24 Aug 2026 · Iron · recommends · YouTube ↗
      Recommends iron from meat, specifically red meat and beef liver, stating that it is a crucial part of the mechanistic triad for thyroid hormone function and is iron-dependent for iodine incorporation into thyroid hormone.
    • 19 Aug 2026 · recommends · YouTube ↗
      Recommends consuming a little bit of vitamin C, such as a couple of berries or kiwi, along with flavanol-rich cocoa to help the delicate flavanols hold up and prevent oxidation in the gut.
    • 12 Aug 2026 · Calcium · recommends · YouTube ↗
      Recommends getting calcium, along with vitamin D, zinc, and magnesium, from foods like sardines, as they are important for inflammatory pathways in the gut.
    • 12 Aug 2026 · Vitamin A · recommends · YouTube ↗
      Recommends vitamin A, obtainable from eggs, dairy, and liver, as a raw material for goblet cells to produce mucus.
    • 8 Aug 2026 · neutral · YouTube ↗
      Explains that vitamin C improves the ability of neutrophils to engulf bacterial infections, and that they have a greater ability to engulf larger infections.
  • Dave Asprey · Vitamin C · recommends
    • 24 Oct 2026 · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 7 Oct 2026 · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 3 Sep 2026 · Vitamin A · recommends · YouTube ↗
      Recommends real vitamin A for people on the spectrum, noting that many cannot convert plant vitamin A and need the good stuff he includes in his Vitam DAKNE product.
    • 14 Aug 2026 · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
    • 12 Aug 2026 · Vitamin A · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
    • 25 Jul 2026 · neutral · Facebook ↗
      Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
    • 19 Jul 2026 · Vitamin A · uses · Facebook ↗
      Includes vitamin K2 as a critical ingredient in Vitamin DAKE, stating that the body needs the right fat soluble vitamins for thousands of reactions.
    • 16 Jul 2026 · warns · YouTube ↗
      Dave Asprey recommends taking maybe a gram of vitamin C a day in divided doses, noting that plasma levels peak around 250 milligrams twice a day.
    • 14 Jul 2026 · recommends · YouTube ↗
      Recommends Qualia Vitamin C Plus, highlighting its combination of seven forms of vitamin C with 250 mg of citrus bioflavonoids, which helps with absorption and use for building collagen and a strong immune system.
    • 9 Jul 2026 · warns · YouTube ↗
      Warns that taking too much vitamin C can raise oxalate levels, emphasizing that everything has risk and reward.
    • 24 Jun 2026 · Iron · warns · X ↗
      Warns that if a doctor diagnoses anemia, one should not assume they just need more iron, as low hemoglobin doesn't always mean low iron and the issue can sometimes be how well the body is using iron.
    • 16 Jun 2026 · Iron · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for iron, which is associated with impaired recovery.
    • 16 Jun 2026 · Calcium · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
    • 14 Jun 2026 · recommends · Podcast ↗
      Recommends Vitamin C as the real biological fix for deep focus issues, explaining how the brain hoards it at levels 100 times higher than blood and how to bypass the blood-brain barrier.
  • Dr. Mark Hyman · Iron · neutral
    • 21 Oct 2026 · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 19 Oct 2026 · Vitamin A · neutral · YouTube ↗
      Mentions that vitamin A levels can be looked at to get a deep sense of what's happening with nutrient levels.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · Vitamin A · recommends · YouTube ↗
      Recommends taking 50,000 units of vitamin A for three to five days right at the onset of symptoms if one feels they might be getting sick.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · Vitamin A · neutral · YouTube ↗
      Notes that night blindness is caused by vitamin A deficiency.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 14 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
    • 9 Sep 2026 · Vitamin C · uses · YouTube ↗
      Used intravenous vitamin C cocktails to help him detoxify and recover from chronic fatigue.
    • 2 Sep 2026 · Vitamin A · neutral · YouTube ↗
      Mentions vitamin A as something that might be helpful for gut repair.
    • 31 Aug 2026 · neutral · YouTube ↗
      Notes that a woman patient had very low iron.
  • Dr. Rhonda Patrick · Vitamin C · neutral
    • 25 Aug 2026 · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin A · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 29 Jun 2026 · Calcium · neutral · Facebook ↗
      Mentions that kale delivers calcium, a micronutrient many diets fall short on.
    • 5 Jun 2026 · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 4 May 2026 · Iron · uses · YouTube ↗
      Recently found out he needed to get on an iron supplement and noticed he gets less sore in his training after taking it.
    • 5 Feb 2026 · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 5 Feb 2026 · Vitamin A · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 22 Jan 2026 · Iron · recommends · YouTube ↗
      Advises that menstruating women should ensure they are getting enough iron.
    • 9 Jan 2026 · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 9 Jan 2026 · Calcium · neutral · Facebook ↗
      Notes additional gaps in calcium.
    • 29 Dec 2025 · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 9 Sep 2025 · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
    • 9 Sep 2025 · Vitamin A · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
  • Andrew Huberman · Iron · recommends
    • 20 Jul 2026 · recommends · YouTube ↗
      States that Iron is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 17 Jun 2026 · Vitamin A · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 30 Oct 2025 · warns · YouTube ↗
      Warns that excess iron will increase the number of senescent cells in the body, which accumulate as people get older and cause inflammation and cancer. He notes that people who are healthy and have a fairly vegetarian diet often have slightly low iron levels but super amounts of energy.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
    • 16 Jun 2025 · Vitamin C · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
    • 16 Jun 2025 · Vitamin A · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
    • 28 Apr 2025 · Vitamin C · uses · YouTube ↗
      Started taking AG1 in 2012 and still takes it every single day to ensure he meets his quota for daily vitamins and minerals and to support gut health, which is critical for proper brain function, immune system, and neurotransmitter production.
    • 24 Apr 2025 · Vitamin A · recommends · Podcast ↗
      Highlights Vitamin A as essential for vision and recommends it for supporting vision.
    • 24 Apr 2025 · Vitamin A · neutral · YouTube ↗
      Mentions that the process of converting light into electrical signals in the retina requires vitamin A, a fat-soluble vitamin, and carotenoids, which is why carrots are said to help vision.
    • 14 Apr 2025 · neutral · YouTube ↗
      Notes that about 50% of the population is iron deficient.
    • 31 Mar 2025 · neutral · Instagram ↗
      Mentions that the podcast will review the role of iron in treating depression.
    • 31 Mar 2025 · warns · YouTube ↗
      States that B12, folate, and iron are essential to mitochondrial function and if deficient, mitochondria will not function properly, which is consistent with the mitochondrial theory of neuropsychiatric disorders.
  • Bryan Johnson · Iron · stopped
    • 8 Jul 2026 · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 5 Jun 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
    • 12 May 2025 · Calcium · recommends · YouTube ↗
      Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 26 Sep 2023 · uses · YouTube ↗
      Takes 10 milligrams of heme iron to get his iron levels up, as they are borderline.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • Date not recorded · recommends · Website ↗
      Recommends adequate Iron for hair health, noting it is in the Blueprint stack.
    • Date not recorded · recommends · Source ↗
      Recommends supplementing with iron for brain health for both the mother and the baby during pregnancy.
    • Date not recorded · Calcium · recommends · Website ↗
      Recommends prioritizing calcium intake for postmenopausal women to help maintain bone density and reduce the risk of osteoporosis.
    • Date not recorded · Calcium · uses · Website ↗
      Bryan Johnson takes Calcium daily as part of his Longevity Mix, which supports healthy bones and teeth.
    • Date not recorded · Calcium · recommends · Source ↗
      Recommends continuing with calcium to support bone health during the follicular phase.
    • Date not recorded · Vitamin C · recommends · Website ↗
      Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
  • Peter Attia · Vitamin A · neutral
    • 6 Aug 2025 · neutral · YouTube ↗
      Notes that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin A for male mice.
    • 20 Jul 2025 · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin A for male mice.
    • 9 Jul 2025 · Calcium · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 6 Jul 2025 · Calcium · neutral · YouTube ↗
      Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 8 Jun 2025 · Iron · recommends · YouTube ↗
      Recommends iron supplements for women of reproductive age who are iron deficient.
    • 1 Jun 2025 · neutral · YouTube ↗
      Mentions that a lot of the profound transformation of a cell into a sperm, specifically the making of a tail, is vitamin A driven.
    • 22 Oct 2024 · Calcium · recommends · YouTube ↗
      Recommends calcium for bone health, stating that teenagers probably need about 1000 milligrams a day.
    • 21 Oct 2024 · Calcium · recommends · YouTube ↗
      Discusses bone acting as a reservoir for calcium and how resorption and formation release calcium into the blood when needed.
    • 9 Sep 2024 · Iron · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as iron, can be a cause of hair loss in women.
    • 6 Sep 2024 · neutral · YouTube ↗
      Notes that antioxidants like vitamins A, C, and E have been looked at for cataract formation but have shown no effect.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.

RAL Summary

Members OnlyTier 4 for Muscle and Strength

The study support behind this grade comes only from trace vitamins and minerals with hidden amounts, not from the protein and carbohydrate that make up this mass gainer, and those trace nutrient studies mostly show no muscle benefit. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.
  • Vitamin A: amount hidden in a blend

Where the evidence disagrees: 38 of the 70 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Muscular system, Digestive system

Combine with: Smart Mass is a mass-gainer style product that pairs whey protein with maltodextrin carbohydrates to supply protein and calories for muscle growth. Creatine monohydrate (3-5 g daily) is the best-supported addition for strength and lean mass gains. Add a source of leucine or EAAs around workouts to strengthen muscle protein synthesis, especially if total daily protein is low. Vitamin D3 with K2 and magnesium support muscle function, recovery, and hormonal health. Omega-3 fish oil helps manage exercise-related inflammation, and a digestive enzyme or probiotic may help if the high-calorie shake causes bloating. Pair the product with progressive resistance training, adequate sleep, and a total daily protein intake of roughly 1.6-2.2 g/kg of body weight for best results.

Possible side effects: No major side effects reported. One buyer said it did not cause bloating.

Supplement Facts

Total Carbohydrates 60 g · Vitamin A 0 · Calcium 0
Supplement Facts
Serving Size 124 Gram(s)
Servings Per Container 28
Amount Per Serving% Daily Value
Calories440
Total Fat3 g
Cholesterol50 mg
Sodium460 mg
Total Carbohydrates60 g
Protein40 g
Vitamin A0
Calcium0
Vitamin C0
Iron0

Other ingredients: Carb10, Milk Protein isolate, Whey Protein concentrate, whole Oat bran, Palatinose, Natural and Artificial flavor, Alkalized Cocoa powder, Salt, Guar Gum, Sucralose, Acesulfame Potassium, Amylase, Protease, Protease, Alpha Galactosidase, Glucoamylase, Lactase, Protease, Invertase, Lipase, Acid Maltase, Peptidase.

Directions: Directions: Mix one scoop of Smart Mass with 16 oz cold water. Amount of water can be adjusted to meet your taste preference. To increase your protein intake per serving or to achieve a richer taste, use non-fat or low fat milk, or a milk substitute. Consume enough protein to meet your daily protein requirement through a combination of high protein foods and protein supplements.

Barcode (UPC) 040232661136 · Label source: NIH label database · Report a label change

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Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.